LOCUS       c00118_gnlPro..        15977 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KLMIHPGK_118.
ACCESSION   c00118_gnlPro..
VERSION     c00118_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 10:25:04
            Original ID  :: gnl|Prokka|KLMIHPGK_118
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15977
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..66)
                     /locus_tag="ctg118_1"
                     /transl_table=11
                     /translation="MCLRWKHYLTGTFVLSDGVSQT"
     protocluster    1..15977
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5177:8735](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5178..8735
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..15977
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15977
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(180..284)
                     /locus_tag="ctg118_2"
                     /transl_table=11
                     /translation="MKYILFITMDLAVYPFLLLIYIVKCIFDKIQPAH"
     CDS             637..1503
                     /locus_tag="ctg118_3"
                     /transl_table=11
                     /translation="VLVLAASPSFVSCGGQRPVRFGVVTDLHYSRREPYGTRYFPQTMD
                     KLKEAMEVFNSSNLDFVIEMGDLKDQDNVSQREQTITYLDEIENVFQSFRGPVYHVLGN
                     HDMDSISKDDFLQHTSNQGDADKKAYYSFAFDNIKFIVLDANYNLDGTPYDKGNFDWTK
                     AYIPKDQIDWLKKELKGNNKPVIIFIHQLLDRFSDISKSLCVSNADEIVPLLEENGNVL
                     AVFQGHHHAGHYSFRNNIHYWTMKGMIEGNLPDNNSFAVVEIDTQNNIHIDGFYNCEDK
                     DLNRFTV"
     CDS             complement(1726..2676)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_4"
                     /sec_met_domain="MTHFR (E-value: 2.9e-64, bitscore: 207.1,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKY
                     INITSHHSEYIYKTLPDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDE
                     TEYALIDLNFLGVYDLLLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGST
                     FEANETPFSYGMACYPEKHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVE
                     RCRAEGIDVPIIPGIKPVVFKNQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEW
                     CIQQCKDLIAHGVPSLHFYTMMATDSVYKVAKEVY"
     CDS             2760..3779
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_5"
                     /sec_met_domain="Aminotran_4 (E-value: 1.3e-32, bitscore:
                     103.4, seeds: 70, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENMNWSDLAFGYMKTDYNVRCYYRDGKWGELEVSSSEIINIHMA
                     ATCLHYGQESFEGLKAFKGKDGRIRVFRMDENGKRMQASSRGIKMAELPVEMFEEAVRK
                     VVKLNERFVPPYESGAALYIRPLMIGLGAQVGVKPAPEYMFMVFVTPVGPYFKGGFKPS
                     KVCIMREYDRAAPYGTGTIKVGGNYAASLVAGEIAHEKGYAAVLYLDPKEKKYLDECGP
                     ANFFGIRGNSYITPQSHSILPSITNKSLQQLAEDMGLTVERRPVPFEEIATFDEAAECG
                     TAAVIAPISQIDDLDENKSYVIAKDGKPGPVCEKLYNKLRGIQYGDEPDTYGWVTVIE"
     CDS             3967..5145
                     /locus_tag="ctg118_6"
                     /transl_table=11
                     /translation="VEAFFKTHKYLVEHLHAPVRRGLMDEIDWNDRLIGIKGSRGVGKT
                     TFLLDYAREHFGADNKECLYINLNHFYFTERTLVDFASEFRAKGGKVLLIDQVFKYSGW
                     SKELRYCYDNFEDLKIIFSGSSVMRLKEENPDLSGKVVSYNLRGFSFREFLNLMSGNSF
                     PAYTFEEIIGNHQEIAKNICSVAKPMAYFQDYLHHGFYPFFLEKRNFSENLLKTMNMML
                     EVDVLYIKQIEQSYLPKLRKLLYLLAISAPCTPNVSQLSKEIETSRATVMNYIKYLTDA
                     RLMNMLYPVGESFPKKPSTVYMYNSNLMYPIRPMEVNVQAVRESFFYNQLLKDNTLNEG
                     MKNAHFLVNGKYNFRIEESMKVKNNPDLYYAVDKVEVGEENMIPLWLFGFLY"
     CDS             5178..8735
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_7"
                     /sec_met_domain="PFOR_II (E-value: 9.9e-20, bitscore: 60.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.7e-83, bitscore: 268.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 3.9e-32, bitscore: 101.7,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.6e-13, bitscore:
                     39.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 5.3e-13, bitscore: 39.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.8e-08, bitscore: 21.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.4e-05, bitscore: 14.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1e-24, bitscore: 76.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFLTCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVMVQEMQSEGGAAGAVHGSLQAGALTSTYTASQGLLLMIPNMYKIAG
                     ELLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFVNFFDGFRTSHEIQKIEALENDDLAPLIDQKALAEFRARALNPEKPEARGMAE
                     NPDHFFQHRESSNKYYEAVPAIVEEYMNEISKLTGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLTAQGEKVGLVSVHLYRPFSAKHFLAAVPKTAKRIAVLDRTKEPGATGE
                     PLYLDVKDCFYGQADAPVIVGGRYGLGSKDTTPAQILAVYENLALPMPKNQFTLGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKYCQAYFSYDS
                     KKSGGFTCSHLRFGDHPIRSTYLVNTPNFVACHVQAYLRMYDVTRGLRENGTFLLNTVW
                     NGEELAKHLPNKVKRYFAQKNITVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DLAIEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYTQLTVDPDWANLPDDEVVANNDP
                     AFINEVVRPINAQDGDLLKVSAFEGIEDGTWHQGTAKYEKRGVAAFVPVWEPDNCIQCN
                     KCAYVCPHASIRPFVLDAAEQAAAPFNNSLKATGKQFEGMQFRIQVDVLDCLGCGNCAD
                     VCPGNPKKGGKALKMAALETQLDEAPNWDFCAEKVTTKQHLVDIKANVKNSQFATPLFE
                     FSGACSGCGETPYVKLVTQLFGDREMVANATGCSSIYSGSVPSTPYTTNDKGQGPAWAN
                     SLFEDFCEFGLGMELANEKMRARLTNAMNEIIAADNAPAEAKEVLKAWVENQNDADKTK
                     ELAPQVLAIAEEGITHGCPLSAQIKELSHFLVKRSQWIIGGDGASYDIGYGGLDHVIAS
                     GKNVNILVLDTEVYSNTGGQSSKATPVGAIAKFAASGKRIRKKDLGLMATTYGYVYVAQ
                     IAMGADQAQTLKAIREAEAYDGPSLIIAYAPCINHGLKKGMGKSQQEEADAVACGYWHL
                     WRYNPALEEEGKNPFTLDSKEPDWSKFQDFLKGEVRFASLTKQFPAEAAQLFQAAEDNA
                     KWRLNNYKRLAKQQWGVEE"
     CDS             8845..9501
                     /locus_tag="ctg118_8"
                     /transl_table=11
                     /translation="MAKNKSKQNQFQLLSPEKYIRLKARNLPIEVCYVSDDWKDERGAV
                     AEVIVVRRHAGGNYTFGVYVVDTLCLGVKHSVYRFNVPPDEYDDFVERTATDCGIKISY
                     NEAHNFIYGAIAFAEEFGIKPDKSFALTQYILEEDTEEIPLIEYKYGRGGRPHLVAETS
                     LEASKYIPILEESTGGDFGLEILEDRDVFDDDEFDDEFDDDEFDDEYDEEDNKTM"
     CDS             complement(9681..10715)
                     /locus_tag="ctg118_9"
                     /transl_table=11
                     /translation="MEYRQLGGSGLYVPVLCLGTATFGGTNGFEGWGHTQVDEARRMIN
                     LCLDAGVNLFDTADAYSDGLSETILGKAVEGLRNKLLISTKATFNLNPEGRNAMGSSRF
                     HLIEACEASLKRLNTDHIDIYHMHGFDANTPVEETLRALDDLITAGKIRYIACSNFSGW
                     HLMKALSVSERYGWSRYVAQQVHYSLLNREFEWELMPLGIDQKVGSIIWSPLSAGRLGG
                     RYRRNNPIPADGRVARGGSPIPDEATSYERLYNIMDVLDEIAEETGHSVAQCALNWLLQ
                     RPTVSSLIIGASTEEQLKQNLEAVGWNLTPEQVKRLDNASQVTPIYPYWHQAQFPFLNA
                     QIQF"
     CDS             10825..11601
                     /locus_tag="ctg118_10"
                     /transl_table=11
                     /translation="MVKAIFFDIDGTLVSFKTHEVPRSTIDALDILRKKGIKVFIATGR
                     HYSSINNLGDLKFDGYVTLNGGYCFAGEDKVIYKHSIPDRDIDALIRYLETEESFPCAF
                     VQEKEIFMNYKDETVEEIFNMLNFPEPPIRPLSEMKGKTVYQLVSFFTAEQEKKIMSIL
                     SHCESTRWNPLFTDVVPAGSSKRIGIDKMLEYFKIPLKECMAFGDGGNDIAMLQHAGIG
                     VAMGNADDDVKQYADYVTDSVDEDGIFKALKFHNII"
     CDS             11655..12197
                     /locus_tag="ctg118_11"
                     /transl_table=11
                     /translation="MIDELLEYNRGFVDKKGYEKFITNKYPDKKIAIVSCMDTRLIELL
                     PAALGIKNGDVKIIKNAGAIISHPFGSVIRSLMVAIYELGVVEIMIIGHSDCGAQHMDS
                     DEMIEAMKKRGIPAERIDMIRYCGIDFKYWLRGFDSTECSVKDTVEQVRNHPLIPTDIT
                     VRGFVINSVTGELTEVE"
     CDS             12387..12545
                     /locus_tag="ctg118_12"
                     /transl_table=11
                     /translation="MMTSRNEENLRTLAMLRYQADRYQSMRNGTMSQRVNAEIRRLLEE
                     MGANAKN"
     CDS             12759..13757
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_13"
                     /sec_met_domain="Peptidase_M20 (E-value: 5.6e-12, bitscore:
                     35.7, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTGLFVASVMLSTTLWAQSPVEKGLNTINKENAEAYIGFLASD
                     ELEGREAGFQGGRIAAEYIVSNLKTMGIAPLNESYYQPFEAYNKERQKRGRFQVHPDSI
                     AQLKQGVHQKLSMRNILGKIEGKNPNEYVIIGAHYDHLGFDPMLDGDQIYNGADDNASG
                     VSAVLQVAKAFLASGEQPQRTVIFAFWDGEEKGLLGSEYFVQNCPFLKDIKGYLNYDMI
                     GRNSNEVVPEQVDYFYTEANKAFGDWLKNDIKKYNLNLKPIYHPWDKPVGGSDNGSFAK
                     RGIPIIWYHTNGHPDYHMPGDHVEKINWDKIVDITKASFLNMWNLANEKKY"
     CDS             complement(13824..14366)
                     /locus_tag="ctg118_14"
                     /transl_table=11
                     /translation="MKSINVILYWVIVMVIGLSACGDDDEKTIPAHTEEEKIWIADNQK
                     YFQEKKEDVEDDGQLLYQRLVVDEDTLLYRVLETSQIDSFPKIDADVKVSMLGVIPVSQ
                     TVIVGNKDGNPIDQTLKLDSPNLIKGLAALLPKIRKGERVDAIIPYQLGYGDRNYSNPY
                     IPLCSTLQFTFTVKSFD"
     CDS             complement(14473..15975)
                     /locus_tag="ctg118_15"
                     /transl_table=11
                     /translation="IVRPWDGWSGTPFNEFIFTQTCTNYSKELSGMKLLYADMTEEEQE
                     QNKVYMLCSDIIRSYAFQRATDLYDDMPYSEAGGAFQELFYPKYDTQEEIYMNIMETLK
                     NAAAELSEYQFQTDAQESKFSSVDILCNGDLDKWIRMANSLRLRMAMRLCHVKPDAALS
                     TIKELIAENRMLTEYSHDLGFEEQDKTHAFELTFFRGLDERGYESGAPATIIEDIMNYE
                     YQPGDENGITRHDFDPRLYAMFQPDIHGRYIGLPLTIEEAEAELPNYYTEKELTDMYNF
                     NDVVTNPWNPERIPTMYNRRTYFNFDMKFPVMGSTETNLLLAEAAVRWPGELGNIDVKS
                     CIKKAIDASTRFYYNVNKTMSYNESSLPSILYVQAKAKAPELDEDHLADYEELAANKFA
                     SLTSTKDKLKFIFDQKFCHMNIMNPYEIYNEARRLVKDFDGELPFVSTPNVVFQERMFY
                     PSSELTNNGDNFAKVAHKNTYDTPVWWTGRTTPAENHNGNAL"
ORIGIN
        1 ggtttgggaa actccatcgc ttaagacaaa agtccctgta agataatgtt tccagcgaag
       61 acacattata agaagcaatt aaaaaggcct ttttataaat ccatgtaaat tataccgaat
      121 gaattttgtc aggatgttca ttcggtataa tttgttttta agttcttttg tattgaaaat
      181 cagtgagctg gttgtatctt atcaaagatg cattttacta tataaattag tagcagaaaa
      241 ggatatactg ccagatccat agtaatgaat agtatgtatt tcatttcttt tttcttttaa
      301 attccacctg taagacagaa atatttcaaa aacccctatc ggcctgacag atttttttgt
      361 atttgtatga aaagaagatg agcaaaggct ctaaaaagat gcatctgggt ttgaaattgg
      421 ggtaatttaa caaataagct tttttcggga gattgaaaat ttgttctcaa ctcatcctaa
      481 atccgggatg gtagatatat tgacttttta ttattaatat tgtaagccaa tgctgatagc
      541 ctgctacatc cggcaggtta ccggcatgac tctataacct atgaaatttt taatatgatg
      601 aacagacgct tatttttaaa aaaggcatgc ggaggggtgt tggtcctggc agcttctcct
      661 tcatttgtat cctgtggtgg acaacggcct gtccggtttg gggttgttac cgatctgcat
      721 tattcgcggc gggaacctta tgggacccgt tatttccctc agacaatgga taagttgaaa
      781 gaggccatgg aggtcttcaa ctcttccaat ctggattttg tgatcgaaat gggcgatctg
      841 aaggatcagg ataacgtctc tcagcgggaa cagacaatta cttatctgga tgaaatagaa
      901 aacgtctttc aatcgttccg gggaccggtt tatcatgtcc tgggaaatca tgatatggat
      961 agcatctcca aagacgattt cctgcaacat acctccaatc agggggatgc cgacaagaaa
     1021 gcttattatt catttgcctt tgataatata aaattcatag tcctggatgc gaattacaat
     1081 ttggacggta caccgtatga taaaggtaat tttgactgga caaaggcata tattcctaaa
     1141 gaccagatag actggttgaa aaaagaattg aaaggaaata acaaaccggt catcattttt
     1201 atccatcagt tgttagaccg cttctccgat atcagtaaat cgctttgtgt aagtaatgcg
     1261 gacgaaatag ttcctctgtt ggaagaaaat gggaatgtgc tagctgtatt ccagggacat
     1321 catcatgcgg gacattacag tttccgtaat aatatccact actggacaat gaaagggatg
     1381 atagaaggaa accttcccga taacaacagt tttgctgttg tggagatcga tacgcagaat
     1441 aatattcata tcgatggttt ctataattgt gaagataagg atttgaatcg cttcacggtg
     1501 taaagttatt cagttgatct gcgtaaagca atctaatgtt ttttcagaca gaggtaggtc
     1561 taaataaatt tagaggtagg tgtaaattga attagaggta cgtctaaatt catttacacc
     1621 tacctctaat ttataagaca tagtaatgtt ctccggattt agtcagtatt acgcttttta
     1681 tccaatccgt tgtctcctgg caatcgatta gttccatcaa cgattttaat atacttcttt
     1741 tgccacttta taaacactat ccgtagccat cattgtataa aaatgcaggc tggggacacc
     1801 gtgggcgatc aggtctttgc attgctggat gcaccattcc acgccaaccg cttttacttc
     1861 atcatcattt ttgcatttgc gcaattcggc tgcaaacggt tcgggaatgt ctgagcggaa
     1921 tattttaggt aatacggtca gctggttttt aaagacaacc ggcttgatgc ctgggatgat
     1981 cgggacatcg ataccttcgg cacggcagcg ttccacaaat gaataatatt tttcattatc
     2041 gaaaaacatc tgggtaacca gatagtcggc accgtttttt actttctctt tcagataaaa
     2101 aatatccgat tccatattcg gtgcttcctc atgtttttcc ggatagcaag ccataccgta
     2161 tgagaacggt gtttcgtttg cttcgaatgt ggaaccgtct acggcaatac ctttattgaa
     2221 attgtttacc tgttcctgaa ggtcagtcgc atgttcgtga tataaatccg tattttgtcc
     2281 ggcttccagt gtttttacat caccacgcaa cagcagcagg tcgtaaactc ccaggaaatt
     2341 aagatcgatc aacgcatatt ccgtttcatc ttttgtaaat cccttacata taatatgtgg
     2401 aactgccgga ataccatatt tgttctggat ggcagaagca atggcaaccg aacccgggcg
     2461 cttgcggatg ttcactttct ggaagctgcc gtcgggcaag gtcttataga tatattcgct
     2521 atggtgagaa gttatattaa tgtatttagg gtcgaattct ttcagtttat caatcacatt
     2581 atataccttc tgtatgctgt tccctttcag aggaggtaga atttcaaatg aaaaagcagt
     2641 cgttttactg ccgttgatca gatcaataac tttcatattt taattatttt tgctgcaaaa
     2701 gtaacaatta tcatccgaaa tagcttactt ttgcgctcat aatctaatta cgacaagata
     2761 tggaaaatat gaattggtct gatctggcat tcggttatat gaagacagac tacaatgtac
     2821 ggtgttacta tcgtgatggt aagtggggtg aattggaagt tagctcttct gaaattatca
     2881 atattcacat ggcagctact tgcctccatt acggacagga gtcgtttgaa ggtttgaaag
     2941 cattcaaggg aaaagacggt agaatccgtg tgttccgtat ggatgaaaac ggcaaacgta
     3001 tgcaagcttc cagccggggc atcaagatgg ctgaacttcc tgtggaaatg tttgaagaag
     3061 cagtccgtaa agttgtgaag ttgaacgagc gttttgttcc tccctatgag agtggagcag
     3121 cattatatat ccgcccgctg atgatcggtt tgggtgcgca ggtgggcgta aaaccggctc
     3181 ccgaatatat gtttatggta ttcgtaaccc cggtaggacc ttatttcaaa ggtggtttca
     3241 aaccgtcaaa ggtttgtatc atgcgtgaat acgaccgtgc tgcgccttat gggactggga
     3301 cgatcaaagt cggtggtaat tatgcagcca gcctggtagc cggagaaata gcgcatgaaa
     3361 aggggtatgc cgccgtattg tatctggacc cgaaagaaaa gaaatatctg gacgaatgcg
     3421 gtcctgccaa cttcttcggt attcgtggaa acagttacat cactccgcag tctcattcta
     3481 ttctgccgtc tatcactaac aagagtttgc agcagctggc tgaagatatg ggactgacgg
     3541 ttgaacgtcg tcctgttcct tttgaagaaa tagctacatt cgatgaagca gcagaatgcg
     3601 gaacagctgc cgttatcgcc ccgatttcac agattgatga tttggatgaa aataaatcat
     3661 acgtgatagc caaggacggt aaacccggac ctgtttgcga aaaactatat aacaaactgc
     3721 gtggcatcca atacggtgac gaacctgata catacggttg ggttacggta attgaataat
     3781 cagataaaag atgttgacag ttaatgtttt tagataaacc ggaagcatta actgccaact
     3841 ctaaattctc aaacgtcaat acgctttgcc aactttggat tgccaactga aaataaaatt
     3901 gctatctcgg tattgcaaag ttgaggatat tttctatctt tgcggtctat atagtaagac
     3961 agtcaggtgg aagcattctt taaaacacat aaataccttg tagaacattt gcatgcaccg
     4021 gtacgccggg ggctgatgga tgagattgat tggaatgacc ggttgatcgg gatcaaaggc
     4081 tctcgtggag tagggaaaac tacttttttg ctggattatg cccgcgaaca ttttggtgct
     4141 gataataaag agtgcctgta tataaatctg aatcactttt attttacgga acgtacgctg
     4201 gtcgactttg cttctgagtt cagggcaaaa ggagggaagg tgttgttgat tgaccaggtt
     4261 ttcaaatatt ccggatggtc gaaagagtta cgttattgtt atgataattt tgaagatctg
     4321 aagattatct tttccggttc gtcagtgatg aggttgaaag aggaaaatcc ggatctctca
     4381 ggtaaagttg tttcatataa tttgcgtggt ttttctttcc gagagttttt gaatctgatg
     4441 tcgggaaaca gttttccggc ttatacgttt gaagaaataa tcgggaacca tcaggagatt
     4501 gcgaagaata tttgttcggt agccaaaccg atggcttatt ttcaggatta tttgcatcat
     4561 ggtttttatc cgttcttcct ggagaaacgc aatttctcag agaacctgtt gaagacaatg
     4621 aatatgatgc tggaggtaga tgtcttgtac atcaagcaaa tcgagcaaag ttatctgccc
     4681 aaactccgca aactgttgta tctgctggct atcagcgcac cgtgtacgcc gaatgtcagt
     4741 cagttgagca aagaaataga aacgtcacgg gctacagtga tgaattatat aaaatatctg
     4801 accgatgccc gtttaatgaa tatgttatat ccggtaggcg aatcgtttcc gaaaaaacca
     4861 tctaccgtgt atatgtacaa ttcgaatctg atgtacccca tccgtccgat ggaggtaaat
     4921 gtgcaggctg tgcgcgaatc ttttttctat aaccagcttt tgaaagacaa tacgctaaat
     4981 gagggaatga agaacgcaca ctttttggta aacggaaagt ataatttcag gatagaggaa
     5041 agtatgaaag taaaaaacaa tcccgattta tactatgctg tagacaaggt cgaagtagga
     5101 gaagagaata tgatcccgct ttggctgttt ggctttttat actaagaaat tcttttaaat
     5161 actaatagta aaagtctatg acaaaacaga agaaattttt gacctgtgat ggtaaccagg
     5221 ctgctgctca tatttcatat atgttcagcg aagtagccgc tatctacccc atcactccgt
     5281 cgtctacaat ggcagaatat gtagacgaat gggctgccgc cggacgtaag aacattttcg
     5341 gcgaaactgt tatggtacag gaaatgcaat cagaaggtgg tgctgcaggt gcagttcacg
     5401 gttctttgca ggctggtgcc ctgacttcaa cttacacggc ttctcaggga ttgttgctga
     5461 tgatccctaa catgtacaag attgccggtg agttgcttcc ttgcgtattc catgtatctg
     5521 cccgtacact ggcatctcat gccttgtgta tcttcggcga tcatcaggat gttatgtctg
     5581 ctcgtcagac tggtttcgca atgttggcag aaggttctgt tcaggaagtt atggacttgg
     5641 cgggtgtagc tcacctggct actatcaagt ctcgcgttcc tttcgtgaac ttcttcgacg
     5701 gtttccgtac atctcacgaa atccagaaga tcgaagctct ggaaaatgat gacctggctc
     5761 cgctgatcga ccagaaggcg ttggctgaat tccgtgcacg tgctttgaat ccggaaaaac
     5821 cggaagctcg cggtatggct gaaaacccgg atcacttctt ccagcacaga gaatcttcaa
     5881 acaaatacta tgaagcagtt cctgctatcg tagaagaata tatgaacgaa atctccaaac
     5941 tcacaggccg taaatatggt ttgttcgatt actacggagc agaagatgca gaacgcgtga
     6001 ttatcgcaat gggttctgta accgaagctg cccgcgaagc tatcgaccac ctgactgctc
     6061 agggtgaaaa agtaggtttg gtttctgttc atttgtatcg tccgttctct gctaagcact
     6121 tcctggcagc tgttcctaag actgcaaaac gtatcgcagt tcttgacaga acaaaagaac
     6181 cgggtgcaac tggcgaacct ttgtatctgg atgtaaaaga ctgtttctac ggacaggctg
     6241 acgctccggt tatcgtgggt ggccgttatg gtctgggttc taaagatact actccggcac
     6301 agattcttgc cgtttacgaa aatctggcat tgccgatgcc gaagaatcag ttcacactgg
     6361 gtatcgtaga cgatgttaca ttcacttctc ttcctcagaa agaagaaatc gctttgggcg
     6421 gtgaaggtat gttcgaagct aaattctacg gattaggtgc tgacggtacg gtgggtgcta
     6481 acaagaactc tgtaaagatt attggtgaca atacagacaa atattgccag gcatacttct
     6541 cttacgactc taagaagtcc ggtggtttca cttgttctca cctgcgtttc ggagatcatc
     6601 cgattcgttc tacttatttg gtaaatactc cgaacttcgt tgcttgtcac gttcaggctt
     6661 atctgcgtat gtacgatgtt actcgcggtt tgcgtgaaaa tggtacattc ctgctgaaca
     6721 ctgtatggaa tggtgaagag ttggctaaac acctgccgaa caaggtaaaa cgttatttcg
     6781 ctcagaaaaa tattactgtt tactatatca atgcaacaca gattgctttg gaaattggtt
     6841 tgggtaaccg taccaataca atccttcagt ctgcattctt ccgcatcaca ggtgtaattc
     6901 ctgttgatct ggctatcgaa cagatgaaga aattcatcgt gaagtcttac ggaaagaagg
     6961 gtgaagatgt agttaacaag aactatgctg ctgtcgatcg tggtggcgaa tatactcaac
     7021 tgacagttga tccggactgg gctaacctgc cggacgatga agttgtagca aacaacgatc
     7081 ctgctttcat caacgaagta gttcgtccta tcaatgctca ggatggtgac ttgctgaaag
     7141 tttctgcatt cgaaggtatc gaagacggta catggcatca gggaacagct aaatatgaaa
     7201 aacgtggtgt agccgctttc gttcctgttt gggaaccgga taactgtatc cagtgtaaca
     7261 agtgtgcata tgtttgtcct cacgcttcta tccgtccgtt cgtgttggat gctgctgaac
     7321 aggctgctgc tccgttcaat aactctttga aagcaacagg taaacaattc gaaggaatgc
     7381 agttccgtat tcaggtagac gttcttgact gtctgggttg tggtaactgt gccgatgttt
     7441 gtccgggtaa tccgaagaag ggtggtaaag cgcttaagat ggctgctttg gaaactcaat
     7501 tggatgaagc tccgaactgg gatttctgtg ctgaaaaggt gacaacaaaa caacatttgg
     7561 ttgacatcaa ggctaacgtg aagaactctc agtttgcaac tccgttgttt gagttctccg
     7621 gtgcttgctc cggttgtggt gaaactccgt acgtgaagtt ggtaactcag ctgttcggtg
     7681 accgtgaaat ggtagctaac gcaacaggtt gttcttctat ctattcaggt tcagtacctt
     7741 ctactcctta tacaacaaat gataagggtc agggtccggc ttgggctaac tcattgttcg
     7801 aagacttctg cgaattcggt ctgggtatgg aattggctaa cgaaaagatg cgtgcacgcc
     7861 tgacaaatgc gatgaacgaa attatcgctg ccgacaatgc tcctgctgaa gctaaggaag
     7921 ttctgaaggc ttgggttgaa aatcagaatg atgccgataa gacaaaagaa ctggctcctc
     7981 aggtattggc tattgctgaa gaaggtatca ctcacgggtg tccgcttagc gcacagatca
     8041 aggagctttc tcacttcctg gtaaaacgtt cacagtggat tatcggtggt gacggtgctt
     8101 cttacgatat cggttacggt ggtcttgacc atgtaattgc ttcaggtaag aacgttaaca
     8161 tcctggtatt ggatactgaa gtttattcaa atacgggagg ccagtcttct aaagctactc
     8221 cggtaggtgc aatcgctaag tttgctgctt ccggtaagag aatccgcaag aaagacctgg
     8281 gtctgatggc tacaacttac ggttatgttt atgttgctca gatcgcaatg ggtgccgacc
     8341 aggctcagac attgaaagcg atccgcgaag ctgaagctta tgatggtcct tcattgatca
     8401 ttgcttacgc tccttgtatc aaccacggtt tgaagaaggg tatgggtaag agccagcagg
     8461 aagaagctga tgcagtagca tgtggttact ggcatttgtg gcgttacaac ccggctttgg
     8521 aagaagaagg caagaatccg ttcactttgg atagcaaaga accggattgg agcaaattcc
     8581 aggacttcct gaagggtgaa gtacgtttcg catctctgac aaaacaattc ccggccgaag
     8641 ccgctcaatt gttccaggct gccgaagaca acgctaagtg gagacttaac aactacaagc
     8701 gtttggctaa acagcagtgg ggtgttgaag aataattgat tatttgatca tctaaatagt
     8761 aaaacggaat cttcgaaaga gggttccgtt tttttgtata agccaaataa atcgtacctt
     8821 tagcgaaact aaacaaacaa gcaaatggcg aaaaataaaa gcaagcagaa tcagtttcag
     8881 ttactctctc ctgaaaagta tattcgtttg aaagctagaa atttaccgat agaggtgtgt
     8941 tatgtttccg atgactggaa agatgaaaga ggggctgtag cggaagtgat cgtagttcgt
     9001 cgtcatgccg gtggaaatta tacattcgga gtttacgtcg tagatacgtt gtgtctggga
     9061 gtgaaacatt ctgtatatag gtttaatgtg ccaccggatg agtatgacga ttttgttgaa
     9121 agaacggcaa ctgattgcgg tattaaaatc agttataatg aagctcataa ttttatttat
     9181 ggggctatag cgtttgccga agagttcggg atcaaaccgg ataagagttt tgccttgacg
     9241 caatatatac tggaagagga tacggaagag attcctttga ttgaatataa atatgggaga
     9301 ggtggccgcc ctcacctggt tgccgaaact tctcttgagg caagtaaata tatccctata
     9361 ctggaagaat ccacaggcgg cgatttcggt cttgagatat tggaagatcg tgatgtgttt
     9421 gatgatgatg aattcgacga cgaattcgat gatgacgaat ttgatgatga atatgacgag
     9481 gaggataata agacaatgta agaatattac aataataata tagagggaat tggttcagtt
     9541 tttgtcaaaa gtgaactatc ctgtccccgt gcttgacacg gggccgcaag agaactggcg
     9601 gtatcaaaag atattatagg aaacggtctg tgcctttgtg atcccgtgtc aagcacggga
     9661 acgggatagc tcaattcttt ctaaaattga atctgtgcat tcaaaaacgg gaattgtgcc
     9721 tggtgccaat atggataaat aggggtgacc tggctggcat tatccagtct ttttacctgt
     9781 tccggtgtca ggttccagcc gacagcctcc agattctgtt ttaattgttc ttctgtgctg
     9841 gccccgatta tcaggctgga aacagttggg cgttgcagta accagttcag cgcacattgt
     9901 gctaccgaat gtcctgtctc ttctgctatt tcatccaata catccattat attatataaa
     9961 cgttcatagg aagtagcttc atcggggata ggacttccgc cgcgagccac acgtccgtcg
    10021 gccggtatcg gattgttgcg ccggtatctt ccgcccagac gtcctgctga aagaggactc
    10081 cagatgatgg aacctacctt ctgatcgatt ccgagcggca ttaattccca ttcaaactcc
    10141 ctgttgagca aagaataatg aacctgctgt gccacataac gactccagcc atagcgttcg
    10201 gagacagaca aagccttcat cagatgccat ccggagaaat tagaacaagc gatataccgt
    10261 atttttccgg cagtgatcag atcatccaga gcgcgaagcg tttcttctac cggcgtattg
    10321 gcgtcaaatc catgcatatg ataaatatca atatgatcgg tattcagccg tttcaggctg
    10381 gcttcgcagg cctcgatgag gtggaagcgg gaagaaccca tagcgttgcg tccttccgga
    10441 ttcaggttga atgtggcttt ggtcgatatc aacagtttat ttctcagtcc ttcaacagct
    10501 tttcccaata tcgtttcaga aagtccgtct gaatatgcgt cagcggtgtc gaacaggttt
    10561 acacccgcat cgagacaaag gtttatcatg cgtctggctt cgtccacttg ggtatgtccc
    10621 catccttcga aaccgtttgt acctccaaaa gtagcagtcc ctaaacaaag cacgggtaca
    10681 taaagtcccg atcctcctaa ttgtctgtat tccatagctt acctattaaa ttgttattaa
    10741 gatcttactt acaaaggtat ataaaaatcc gcatgtgttt atttattctt atctttgtat
    10801 caaatttagg ttattagaaa aagtatggtt aaggcaattt tcttcgatat agacgggacg
    10861 ttggtcagtt ttaagacaca tgaagtaccc cgctctacca ttgacgcatt ggatatctta
    10921 cggaagaaag gtattaaagt ttttatagca acaggtcgtc attacagttc catcaacaat
    10981 ctgggagatt taaaatttga cggatatgtt acactgaacg gtggatattg ttttgccgga
    11041 gaagacaaag tgatctataa acacagcatt cccgacaggg atatcgatgc attgatccgc
    11101 tatttggaaa ctgaagagtc tttcccctgt gcttttgtcc aggaaaaaga aatctttatg
    11161 aattataagg atgaaacagt ggaagaaatt tttaatatgc tgaattttcc ggagccgcct
    11221 atccgtcctc tgagtgaaat gaagggaaag acggtctacc agttagtctc attttttact
    11281 gccgaacagg agaaaaagat catgtctatc ttatcccatt gcgaatccac tcgctggaat
    11341 ccgttgttta ccgatgtggt acctgccggg agcagcaagc ggatcggtat tgataaaatg
    11401 ctggaatact ttaagatacc attaaaagaa tgtatggctt tcggtgatgg cggtaatgat
    11461 atagccatgc ttcagcatgc cgggatcggg gttgctatgg ggaatgctga cgacgacgta
    11521 aaacaatatg cggattatgt aaccgattct gttgatgagg acgggatatt caaagccttg
    11581 aaattccaca acattattta aaccagtgtt gttatttata tagctagtgt tattattaaa
    11641 agaaagacag actcatgata gacgaattac ttgaatacaa ccggggattt gtagataaga
    11701 aaggatatga aaagtttata acgaataagt atcccgataa aaagattgcc atcgtatcct
    11761 gtatggatac tcgtctgata gaattgcttc ctgccgcatt gggcataaag aatggcgacg
    11821 tgaaaatcat aaagaatgcc ggtgcaatca tttcacatcc gttcggcagt gtgatacgca
    11881 gtctgatggt cgctatttat gaactgggag tggtcgagat catgatcatt ggtcattctg
    11941 attgtggtgc ccagcatatg gacagcgacg agatgatcga agcaatgaag aaacggggta
    12001 ttcccgctga gcgaatcgat atgatccgtt actgcggaat cgattttaaa tactggcttc
    12061 gtgggtttga ctcgacagaa tgctcagtaa aagatacagt cgaacaagtt cgcaaccacc
    12121 cgttgattcc taccgatatt acggttagag gctttgtaat taattcagtt acaggtgaat
    12181 tgaccgaagt ggagtaggga ggttatcttc tgaaaatcta tttctataga ttaaataaat
    12241 gtaaagatag aaataattta tatgttttat agcatagttt tggaaaaagt gcttatcttt
    12301 gcactgtaaa caaaaagaaa agattaaggt ttaggttaat tattaacgag tcttccaagc
    12361 gtgggagaca taaaaaagta aagattatga tgacaagtag aaatgaagaa aatcttcgta
    12421 ctttagcgat gttgcgttat caggctgatc gttatcagtc aatgagaaat ggtacaatga
    12481 gtcagcgagt aaatgctgaa atccgtcgcc tgttggaaga aatgggcgct aacgcaaaga
    12541 attaaataaa aagattagta tattagatgt tttctcttca ccaatgtctt ttttaagact
    12601 ggtgagagac aaaaagatgg gcattcgaca ctggaggatc agtgaagatt agcctttttt
    12661 tattttattg tccttacaat tcttcaattt atcttctatc tttgtgatcg gaagctgaaa
    12721 ctaagtattt ccgataattt gtaaaacaca atcatacaat gaaaagaaca ggtttatttg
    12781 tagcatccgt catgctatct accacccttt gggcacagtc gcctgtagaa aaaggactga
    12841 acactatcaa taaggaaaat gcggaagcct atatcggttt cttggccagt gacgaactgg
    12901 aagggcgtga agccggtttc cagggaggac ggattgctgc cgagtatatc gtctccaacc
    12961 tgaagacaat gggcatcgct cccttgaatg agtcttatta ccaacctttc gaggcttata
    13021 ataaggaacg ccagaagagg ggacgttttc aggtgcatcc tgattcgatc gcccaactga
    13081 agcaaggcgt acatcagaag ttatccatgc gtaatatcct gggaaagata gaagggaaga
    13141 atccgaatga atatgttatc atcggagcac actacgatca cctgggtttc gatccgatgc
    13201 tggacggtga tcagatctat aacggggcag atgataatgc ttcgggcgta tcggctgtcc
    13261 ttcaggttgc aaaagcattc ctggcttccg gtgagcaacc gcaacgtacg gtaatctttg
    13321 ctttctggga cggtgaagaa aaaggattgc taggctctga atattttgtg cagaactgtc
    13381 cgttcctgaa agatataaag ggatatttga attatgatat gatcggccgc aattcgaacg
    13441 aagtggttcc cgagcaggtc gattatttct atacggaagc aaacaaggct tttggtgact
    13501 ggctgaagaa tgatatcaag aaatacaatc tgaacctgaa accgatttat cacccctggg
    13561 acaagccggt aggagggagt gacaacggct cttttgccaa acgtggtatt cccattatct
    13621 ggtatcacac caacggtcat ccggactacc atatgccggg cgaccatgtc gaaaagatca
    13681 actgggataa gatcgtagat attacaaaag cctctttcct gaatatgtgg aacttggcga
    13741 atgagaagaa atattagtgt tgaatataaa aaggagagga tctttcaatt tttgaagtga
    13801 aacaacctct cctttttaaa agcttaatca aaacttttta cagtaaaagt aaactgcaac
    13861 gttgagcata atggaatata cggattggag taattacgat ccccatatcc caactgataa
    13921 ggaattatag catccaccct ttctccttta cggattttcg gcaaaagagc agccaggccc
    13981 ttaatcagat tcggactgtc caattttaaa gtctgatcta tcggattacc atctttatta
    14041 cctacgataa ccgtttggga aaccggaatt actcctaaca tagaaacttt tacatcagca
    14101 tctatcttag ggaaagaatc tatttgactc gtttccagta cacgatacaa aagcgtatct
    14161 tcatccacga ctaatcgctg atacagcaat tgtccgtcat cctctacatc ttcctttttt
    14221 tcctgaaaat atttctggtt atcggcaatc catattttct cctcttctgt atgagccggt
    14281 atcgtctttt catcgtcatc accacaagcc gataggccga tcaccatcac tattacccaa
    14341 tacaggatca cattaatcga tttcattttt actcattttg ttaaattatg cagtacattt
    14401 tatagtgaat aaaggctgtc gaaaaagttt ctcgacagcc tttgtgttta tgtagcatta
    14461 agctaatgtt tattacaatg cattaccatt atggttttct gcaggagttg tacgtcctgt
    14521 ccaccaaact ggtgtgtcgt atgtattttt atgagcaact tttgcaaagt tatcaccgtt
    14581 gttagtcaac tcgctggacg gatagaacat acgttcctgg aataccacat taggagtgga
    14641 gacaaacggc agttctccgt cgaagtcttt taccaaacga cgagcttcgt tgtaaatttc
    14701 atacggattc atgatattca tgtggcagaa cttctggtcg aaaatgaatt tcagtttatc
    14761 ttttgttgag gtcaaactag caaacttgtt agcagctagt tcttcataat cagccagatg
    14821 atcttcgtcc aattccggag ctttagcctt tgcctgaaca tacagaatac tcggcagaga
    14881 agattcatta taactcattg ttttattcac attatagtag aaacgagtag aagcatcaat
    14941 ggccttctta atacagcttt taacatcgat attacctaac tcgcccggcc aacgtacagc
    15001 ggcttcagcc aataacaagt ttgtttctgt tgaacccatt accggaaatt tcatatcgaa
    15061 attgaagtaa gtacgacggt tatacattgt aggaatacgt tccggattcc atggattagt
    15121 aaccacatca ttaaaattat acatatcagt caattccttt tctgtataat agttaggaag
    15181 ttccgcttca gcttcttcta ttgttaatgg caaaccaata tagcgtccgt ggatatccgg
    15241 ttggaacatg gcatacaaac gtgggtcaaa atcgtgacga gtgataccat tttcatcacc
    15301 tggctgatat tcataattca tgatatcttc aatgatcgtt gccggtgcac ctgattcata
    15361 tccacgttca tccaaaccac ggaagaatgt cagttcgaag gcatgtgttt tatcctgttc
    15421 ttcaaaacca agatcatgtg aatattctgt caacatgcgg ttttcggcaa tcaactcttt
    15481 aatagtcgaa agagctgcat ccggtttcac atggcagaga cgcattgcca tacgcaaacg
    15541 taaagaatta gccatacgaa tccatttgtc caaatcaccg ttacacaaaa tatctacaga
    15601 agagaatttt gactcttgtg catctgtttg aaattgatat tcacttaatt cagcagccgc
    15661 atttttcaga gtttccatga tattcatgta aatctcttct tgtgtatcat atttaggata
    15721 aaacagttct tggaaagcac ctccggcttc tgaataaggc atatcatcgt ataagtctgt
    15781 tgcacgttgg aatgcataag aacggataat atcactacaa agcatataca ctttgttttg
    15841 ttcttgctct tcttctgtca tgtcggcata caacaatttc atgccactga gttctttgct
    15901 gtaattggta caagtctgtg tgaatataaa ctcattaaac ggagtacctg accagccatc
    15961 ccatggacgg acaatcg
//
