LOCUS       c00087_gnlPro..        14811 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKHBJOCE_87.
ACCESSION   c00087_gnlPro..
VERSION     c00087_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 09:38:47
            Original ID  :: gnl|Prokka|JKHBJOCE_87
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14811
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..576)
                     /locus_tag="ctg87_1"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIE"
     protocluster    1..14811
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[572:4811]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      573..4811
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14811
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14811
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(573..1133)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg87_2"
                     /sec_met_domain="ALS_ss_C (E-value: 7.3e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(1166..2917)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg87_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-47, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAKRPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(3009..4811)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg87_4"
                     /sec_met_domain="ILVD_EDD (E-value: 6.6e-219, bitscore:
                     717.3, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKRLFEDAAKLIVANAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             5302..5874
                     /locus_tag="ctg87_5"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDVVVMDMNHPLAGCDLNFTGEVVESRPATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             complement(5982..7259)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg87_6"
                     /sec_met_domain="SDH_alpha (E-value: 1.8e-62, bitscore:
                     201.0, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETERRQIIALVKSEVIPAIGCTEPIAVALCVAKAAEVLNKRPE
                     KITVLLSANILKNAMGVGIPGTGMIGLPIAVALGALIGKSAYQLEVLKESTPDAVEAGK
                     RFIEEKRIHISLKNDMEEKLYIEVCCEADTDKATAIIAGGHTCFTYITRNGDILLDKQI
                     ASCIEEEDVLDLTLRKVYDFAMTTPLDDIRFILETARLNKAAAERSFEGDYGHGLGKIL
                     RGTYEHKVMGDSVFSHILSYTSGACDARMAGAMIPVMSNSGSGNQGISATLPVLIYAEE
                     NGKSEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGTYEQVAY
                     AVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAIMAMENRCVTSVEGIIDEDVDQS
                     IRNLTKIGSKGMNETDKLVLEIMTSK"
     CDS             complement(7379..8572)
                     /locus_tag="ctg87_7"
                     /transl_table=11
                     /translation="MKKNLFYLFALICSMSLFTACSDDDDDKVVCPVPQTEFTVATGLN
                     LTYNGGSMLGKKVTFTPDASDATKATLVLAGNLDLSGILTREAASGSFGAGVFPGSPVV
                     TLPVTLNIQGDECSFSGTSETDYCTFDYAGKVTASSLKLDLTNVALKNSALSGTTWVPT
                     PLNSDYTEEPIHLIWESNKNVEVMPGWELPIQTILTLALRMPLIDAGGDDKVNVEDMLC
                     SVLHDITLGADGNISASYVDAAQGGTSVVKTPANVAQYVVLSDTQMKVYLNLDAIIANV
                     KRLGSSTKAIDMSEILSQAVTSLLPLVTDGVPLTYEKNEGKLKAYLNTDLLLPLMKNIV
                     APLFSDEEFVNMLIEAMKADPDFGSMAGMAEGMLKGLPEIINETTRLEVGLNLTAAK"
     CDS             8947..10023
                     /locus_tag="ctg87_8"
                     /transl_table=11
                     /translation="MFNSFGNILRLTSFGESHGKGVGGVIDGFPAGIVIDMDFVQAELD
                     RRRPGQSRITTARKEGDKVEFLSGIFEGKSTGCPIGFIVWNQNQHSDDYNNLKEVYRPS
                     HADYTYKVKYGIRDHRGGGRSSARETISRVVAGALAKLALKQLGIHITAYTSQVGPIRL
                     EENYTAYDLDLIETNPVRCPDPAKAKEMEELIFKIKGEGDTIGGVVTCVVKGCPIGLGQ
                     PVFGKLHAALGAAMLSINAAKAFEYGDGFKGLKQKGSEQNDVFYNNNGRIETRTNHSGG
                     IQGGISNGQDIYFRVAFKPVATVLMEQHTVNIDGVDTTLKARGRHDPCVLPRAVPIVEA
                     MTAMTLLDYYLIDRTTQL"
     CDS             10033..11388
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg87_9"
                     /sec_met_domain="Peptidase_M20 (E-value: 2e-37, bitscore:
                     118.5, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKKYITENEPKMLEDLFSLIRIPSISAKPEHHDDMLACAERWA
                     QLLLEAGADEALVMPSKGNPIVFGQKIVDPDAKTVLVYAHYDVMPAEPLELWKSDPFEP
                     EIRDEHIWARGADDDKGQSFIQVKAFEYLVRNELLQTNVKFIFEGEEEIGSPSLESFCQ
                     EHKELLKADVILVSDTSMLGADLPSLTTGLRGLAYWEIEVTGPNRDLHSGHFGGAVANP
                     INVLCQIISQVTDAEGRITVPGFYDDVEEVPQTERDMIARIPFDEEKYKKAIHVKALFG
                     EKGYSTLERNSCRPSFDVCGIWGGYTGEGSKTVLPSKAYAKVSCRLVPHQDHHKISRLF
                     ADYILDIAPDSVQVKVTPMHGGQGYVCPITLPAYQAAEKGFEKAFGKKPLAVRRGGSIP
                     IISTFEQVLGIKTVLMGFGLESNAIHSPNENIPLDIFRKGIEAVVEFYLNYK"
     CDS             11404..12483
                     /locus_tag="ctg87_10"
                     /transl_table=11
                     /translation="MKDFQIQAIGLMSGTSLDGLDVCCCTFRQQAGKWSFHIDCAKGYS
                     YPDAMKQILGTGAQTMSALEFITFHSSYGKFLGERVNEFMQEFGVHPDIIASHGHTIFH
                     EPQKRIMYQIGDGAAIAAETRIPTVSDFRRLDIMLGGQGAPLVPIGDRLLFADYDFCLN
                     IGGFSNISFEQDGRRIAFDISPVNYVINHYCRQIGLEFDRDGEIARQGNICQELLDELN
                     GMDFYHQSGPKSLGREWVETLVYPMLERYGLSMENMLRTFYEHAAWQISRIITARPLPD
                     GNGKLLITGGGAFNKFLIERIDALCPCEIVIPSRQIIEYKEALIFAFLGALYMADTPGC
                     LASVTGATTDNIGGMLFKI"
     CDS             12498..13052
                     /locus_tag="ctg87_11"
                     /transl_table=11
                     /translation="MEKSKDTWTVLSSEYLHRAPWLTVRKDHVVLPNGNHIPSYYILEY
                     PNWVNTIAITRDGQFVFIRQYRHGIQETSYELCAGVCEEEDGSPMVSAQRELLEETGYG
                     NGVWKEFMQISPNPSTHTNITYCFLATDVEKISEQQLEDTENLTVHLLSLQEVKELLQQ
                     GSIRQALMAAPLWKYMAERII"
ORIGIN
        1 ctctatcggg aacaaatcaa gaatgtgttc tatgtaacgg atgctgttca catgcccgtt
       61 aatgtcaata tcactgtatt tggctaccaa agcagcaacc ggttcctttg aggccacctt
      121 tatccgcgaa ggtttttcta tcgggcaagg ctcatcgcaa acataatcta caatgctgcc
      181 actatgaaga gccagcaaat ctgccggctt acgggtattc atgctaatca tcgcccaaac
      241 ggaacgtgca tacccaatct tcttaccctc cttatcgatg atagcgaaat tacggtctgt
      301 aaaaaggcga tagacattct ccacccaagt ctgaatggag aaatcttcgt actgataagg
      361 catttcatcc agttcgacag ccagacggga caatacccaa gtataattgt cctcgtttag
      421 agtcgcgatg ccaaaaccgc ggtcgctggc atggaaaccc gcacaattca acaaatggtt
      481 gcccaatact cccattgtca gccgtccggt aaagtcgaca tgaaacggtt cggcaacaaa
      541 cttgtaggta cctattttat tgttctcgct catcatgatt cctggtgttt actttgacga
      601 tattttgctt cacggtccgc cagatattca ttgacacgct caaagcagct ggtcgtaatg
      661 gctacgcgac ccgaacggac gaactgaagt acgcaatcca actggcgcaa ctcctcataa
      721 agattggtta tttcctcact catgccattc ttctcaacaa tggcaaatac agcattcacc
      781 tccacaatac gggcattgta cttacggatt actttggaca cctccggttt ttcttccagc
      841 gtaggggtcg ttattttata aagggcaatc tcgtgctgat agatttcatc atccgtgaaa
      901 taatgggctt gcagcacatc tattttcttg gtaatctgct tggtcacctt ttcaatggta
      961 tccttatccg tccaagcggt aatggtatat ttatgtaccc ccttgatgga ggaggccgat
     1021 acattcaaac tctcgatgtt tatctgccgg cgggtaaaca cagccgtcac ctgattcagc
     1081 aaaccggcaa agttttccga atgaacaatg attgtatata gttttttatc catagataga
     1141 gtaaattctt taatttcgca tgacttcagc attccaacaa catctgattg accgaaccgc
     1201 ccggaggtgt catcggcatt acatttcctt cttcctccac acaagcttcg agcaggaacg
     1261 gtccgtcagt cgctatcatc tcgtcaatcg cttttgccag ctcctcgcgg gtcattaccc
     1321 tgcgtgcagg aatatcatat gccgaagcaa tcttcatata atccggattc atcatcggag
     1381 taaacgaata acgacgattg aagaacatcg cctgccattg acgaacattg cccaagaagt
     1441 tattgttcaa cagaatcatc ttcaccggag ccttttgttc catgatggta cccagttcct
     1501 gcaggttcat ctgcaagccg ccgtctccca tgaatacgca taccgtgcgg tccggacgtc
     1561 caaaagtggc accgatagct gccggaaggc cgaagcccat agtacccagg ccaccggaag
     1621 taacaatgct acgttccttg ctgtatttga aataacgggc ggacatcatc tgattctggc
     1681 cgacatcagt caccaatatc gcctcgttat gggtagcctc actcacagca cgcaccacct
     1741 cacccatgct tagcgctttt cctgccggat gtaattccgg acggattacc ttttcctctt
     1801 ccacttcctc gtattgccgg aaactgtcaa tccattcctg atggttggcg ggttccagca
     1861 attgggtaac ggcagccagt gtctctttgc aatctcccag gacagcaaca tcagtcttta
     1921 cattcttatc tatttcggca gggtcaatat caaagtggat aatcttcgcc tgcttggcat
     1981 atgtttccaa tttacccgtc acacggtcat caaagcgcat gcctacggcg ataaggacat
     2041 cacatttatt ggtattgata ttgggcccca ggttaccgtg cataccaagc attcctttgt
     2101 tcaacggatg gttcgtaggt aatgcggaaa gtcccaataa agtgcatccg gcaggcattc
     2161 cggctttctc aatgaaagca cgaagctctt gctgggcttc tcccagctcc acgccttgtc
     2221 caaccagcac caaaggccgt ttcgcaccat ttattaattc agcagccttc cgtatggcct
     2281 ccggctccat ttcgggaacg ggaagatagc tacggacata gtccacctta gtaggcgcat
     2341 attctgtttt ctccacttgg gcgtttttag caaaatccag cacgaccggt cccggacgtc
     2401 cgctctttgc cacatagaaa gcacgtgcca ctgcccaggc cacatcttct gcacgacgaa
     2461 tctggtaact ccatttcgtg ataggctgag taatgcctac caagtccact tcctgaaatg
     2521 catccgtacc caagaagttc gtccctacct ggccggcaat gacaacgata ggcgtactgt
     2581 caatcatggc atctgcaatg cccgtgatag tattggtagc acccggtcca ctggtaacca
     2641 gacaaacgcc aacctcgcct gatacacgtg caaagccttg tgccgcatgg gttgctcctt
     2701 gttcatgacg aaccaagatg tggttcaatt ccttccgatg gtcgtataag gcatcgaata
     2761 ccggcatgat gctccctccc ggataaccga aaatagtctt tactccctga tgctccagag
     2821 agcgcatcaa tgcttctgcg cctgttatta gagcctcacc ccgaccctct ccttgggaga
     2881 gggaggaaaa gttactcttt ttattattat cagccatact ttatctattc attatattta
     2941 aaagctcaat agtagcttga aaaatttgtt tcattctctc ctcccctcgc tttcggaaag
     3001 gggggctttt aatcaatcag cctcacagcc cctttgtcag cggaactcac catactggca
     3061 tatgctttca atgctttgga gacttcacgg ttgcgggtta ccggagtcat agggcgtgct
     3121 gcaagctctt catccgtcaa cttcacattg atagaacggt tcggtatatc aatttcgata
     3181 atgtccccat ccttaatctt gccgatatta ccaccggcag ccgcttcggg agaaacatgt
     3241 ccgatactta gtccggaagt accgccacta aaacgcccgt cggtaatcaa tgcacactcc
     3301 ttacccagat ggcgggattt gatataagaa gtaggataaa gcatctcttg catacccggt
     3361 ccacctttcg gcccttcgtg agtgatgacg acgacgtctc cactgaccac ctttccaccc
     3421 agaataccgt cacaagccgc atcttgtgag tcgaagactt tcgctggccc cgtaaatttc
     3481 cagatactct cgtctacacc ggcagtcttg acaacgcaac cgtcctgagc tatatttccc
     3541 ttcaaaaccg ccagaccgcc atccttgctg tatgcatgtt ccaaatcacg gatacaacca
     3601 gtcgcacggt ccgtatcgag ttccttataa gacgcatttt gtgagccgag taccagattg
     3661 aactttccgg ctgccgcact ggagtatttc ttgattgcct ctttacatac attagagctg
     3721 gtaatactat accggtcgat tgcctctgcc aacgtcattc catccacacg gcggacattc
     3781 gtatcgacca atccgccctt ggcaagctca tccatgatgg caatgatgcc accggcacgg
     3841 ttaacgtctt gtacatgata cttttgggta ttgggagcta ccttgcataa gcagggggtc
     3901 ttgcgagaga gcatgtcaat gtcgtccatc ttaaaatccg ctccggcttc gtgagccaca
     3961 gccaacaaat gaagtactgt attagtggaa ccgcccatcg caatatccag cgtcatggca
     4021 ttcaaaaatg cctcgcgagt agcaatactg cgcgggagta cactctcatc cccttcttca
     4081 taatatctaa aggcattcgc tacaatcaac ttagctgcat cctcaaacag tctcttgcga
     4141 ttttcgtgag tggctacaat cgtgccgtta ccgggcagtg ccaatccaat cgcttcattc
     4201 aggcaattca tggaattagc ggtaaacatg cctgagcagc atccgcaagt ggggcaggca
     4261 tgttgctcaa tctgtgccac ctctttatcg cccacacttt catcagcaga tttaatcata
     4321 gcatcaatca aatccaaatg ttgtccgttc cattccccgg cttccatcgg accgcctgaa
     4381 acaaacacag tcggtatatt cagcctcata gccgccatca acatccccgg agtaatcttg
     4441 tcacagttac tgatgcaaac catagcatcc gccttatggg catttaccat atactccaca
     4501 ctatcggcaa tgatatctct tgaaggcagg gaataaagca taccgtcgtg tcccatagcg
     4561 ataccgtcgt caatggcaat cgtattgaac tccgcagcaa aacaccccag cttttcaatc
     4621 tcttccttta caaactggcc tatttcgtgc aggtgtacat gtccggggac gaattgtgta
     4681 aatgaattga ctatagcgat aatgggctta cccatctgtt ccttcttcat accattcgcc
     4741 gtccacaatg cacgggctcc cgccatgcgg cgaccttgtg tgctgaacga gctgcgtaac
     4801 tgatgcttca ttttcaaatc tccttttaat gaaaaagcct ctcccactat agtgagaaag
     4861 gcttaataaa ttatcttcta acgtacgaat acatacataa cctttctcac gctcttgatg
     4921 ccaccaccac gacgcgaata atatgcagga ctgccaggtt aatagatgta tgtaaattca
     4981 taacttaatt cttctttttt gtttcaaacg tgctgcaaag gtaagggctt ttttataatc
     5041 tccaaacaaa ttgaagaaaa aaataagata aatatgaata atcgtaagaa aaaatcgccc
     5101 taaaatccta ttttatcact taacagttct aaatagaacc attcagacag ccaatgtaaa
     5161 tgtattgcca atcattgaaa ccatttaata atctgaaaat taccaaaggc tctctacatc
     5221 ccgaaacaaa taattcgtat ctttgtctct tcaaatactc aaaaaaacag tatttactaa
     5281 ttaaataaag atagaaaatt aatggaaaca gtagaaaaca agtacatcac cgtagcatat
     5341 aagctgtact caatcgaaaa cggagaaaaa gatttcgaag aagaagcacc cgtagagcat
     5401 cctttccagt ttatctcagg tctgggaatg acactcgaac cttttgaagc ccagataaaa
     5461 gacttgcaga taggcgataa attcgacttt accattccgg catcagaagc ttatggtgaa
     5521 tatgacgacg accatgtcat tgacctcccc aaagaaatct tcatgataga aggagaattc
     5581 gacagcgacc gtgtagtgga aggcgctgtc atccccttga tgacttctga aggtcaacgc
     5641 atcaatggaa gtgtagtaga agtaaaggaa gacgtagttg taatggacat gaatcatcca
     5701 ctcgcaggtt gtgatttgaa ctttaccgga gaagtggtgg aaagccgccc ggccacgaac
     5761 gaagagcttg ctgaagttgc ccgtatgatg ggtggcggtt gtggtagctg cggttgtggt
     5821 gactgtggcg acggatgcgg cgaccatgaa tgtggaggcg gatgctgcca ctaaagaatt
     5881 aaaaattaaa gaattaaaaa ttaaagaatc agactacaca gtattaagca tgccgcatgg
     5941 taattcttta atttttaatt ctttaatttt caaattctat attatttact tgtcattatc
     6001 tccaatacca atttatcagt ttcattcatt cctttagaac cgatttttgt cagattacgg
     6061 atactttgat ccacatcctc atcaataata ccttctacgg aagtcacaca acggttttcc
     6121 atggccatga tggctgaaag cactgcggtt gaaactccgg tggttacttt caatgcacaa
     6181 ctgggcttgg caccatcaca aatcattccg gtaagattgg caatcatgtt ctgtacagca
     6241 tatgccacct gttcataagt tcctcccatt agccaagtta taccgcaact ggaacccgta
     6301 gcagcaacca cacaaccgca taaggcagat aagcgtccca aactctgctt gatataaatt
     6361 accgtcaaat ggctcaacat caaggcgcgt atcaattctt cctccgattt tccgttttct
     6421 tcggcataaa tcaaaaccgg caacgtagcg gatatacctt gattaccgct tcctgaatta
     6481 ctcatgaccg gaatcatagc tcctgccata cgggcatcgc aggcaccgga agtataagaa
     6541 agaatatggg aaaaaacact atcccccata accttgtgct cataagtacc gcgaaggatt
     6601 tttcccagac catgtccgta atcaccctca aaagaacgtt ctgcagccgc cttattcaga
     6661 cgggccgttt caaggataaa acggatgtcg tctaatgggg ttgtcatggc gaagtcatac
     6721 actttgcgta aagtcaagtc caatacatcc tcctcttcga tacaagaggc aatttgtttg
     6781 tccaataaga tgtcaccgtt gcgcgttata taagtaaagc aagtatgccc accggcaata
     6841 atagctgttg ccttgtccgt atcagcttca caacatactt ctatataaag cttctcttcc
     6901 atatcgtttt ttaaagatat atgaatgcgc ttttcttcta tgaaacgctt tcctgcctcc
     6961 actgcatcag gagtactttc tttcaaaacc tccaattgat atgccgactt acctattaag
     7021 gcgccaagcg ccacagcaat cggtaatcca atcatccccg tacctggaat acccactccc
     7081 attgcatttt tcagaatatt ggcactcagc aatacagtta tcttttcggg acgcttattc
     7141 agcacttccg cagcctttgc tacacacaat gccacagcta taggttctgt acaaccaatg
     7201 gcaggaatta cttcagattt aaccaaagca ataatctgtc gtctttccgt ttctgtcata
     7261 tcatttctac aatttgatta tttatcatgc aaatgtagga aaaaacaaac aaaaatccct
     7321 cctctataac ctgaaaatca ggagacaaag gagggaaaat tccatatcga aaaaaaagtt
     7381 atttagcggc agtcaagttc aaaccaactt ccaaacgagt tgtttcatta attatttcag
     7441 gtaaaccctt caacatacct tctgccatac cggccatact tccaaaatca ggatcagctt
     7501 tcattgcttc gataagcata ttcacaaact cctcatccga gaataaagga gcaactatat
     7561 ttttcatcaa aggcaataac aaatccgtat tcaaataagc ctttaattta ccttcgttct
     7621 tttcgtaagt caaaggcaca ccgtcagtta ccaaaggaag caaagacgta acagcctgag
     7681 acaagatttc actcatatcg atagccttgg tagaactgcc cagacgtttt acattggcga
     7741 tgatagcatc cagattcaaa tataccttca tttgggtatc actgagaacc acatattgtg
     7801 caacattcgc aggagtctta acaacagagg tacctccctg agcggcatca acataagaag
     7861 cagaaatatt accgtcagca cccaaagtaa tatcatgcaa cacactacac aacatatcct
     7921 ctacattcac tttatcatca ccacctgcgt caattaaagg catacgaaga gctaacgtca
     7981 aaattgtttg aatcggtagc tcccagccag gcattacctc tacattctta ttggattccc
     8041 aaatcaaatg aatcggttct tccgtataat cagaattaag gggtgtagga acccaagttg
     8101 ttccggataa agcggaattt ttcaatgcga cattagttaa atctaatttc aaggaagaag
     8161 cagtaacctt tcctgcatag tcaaaagtac aataatcggt ctcacttgtg ccggaaaacg
     8221 aacattcatc accttgtata ttcaaagtaa ccggaagggt tacaaccgga gaaccaggga
     8281 atacgcctgc accaaaagaa ccggaagccg cttcacgtgt aagaataccg gaaagatcca
     8341 aattgccagc caataccaaa gtagccttgg ttgcatcaga agcatccgga gtaaaagtta
     8401 ctttctttcc caacattgat ccaccgttat aagtcaagtt caaacctgtt gcaactgtaa
     8461 actctgtttg cggcacagga catactacct tgtcatcgtc atcatcacta caagccgtga
     8521 ataaactcat tgaacagatc aatgcaaata aataaaataa attctttttc atactttttt
     8581 gagtacttgt ttagttaata aaaagcttcc caagggagct attaatttcc cattttaaat
     8641 caaaggtgca aagtaacact ttttaaggtt acagtacaag gtcttttcta aaaaataaat
     8701 gttccttttt tcatcattac gagtgaaatt cggatgcaga tttcataaag agtaagccat
     8761 ttttataaag aacaagccat tgaccaaact ctggcaaagg caggcaactt tatgcggaaa
     8821 agacttttta tcttatttcc ttaaacgttt tatgaaaaaa agttgttatc tttataaagt
     8881 caaaagcatt tcttataaag cgtattggca cattaacctc atatataaac ctttaaagca
     8941 tttgatatgt tcaactcatt tggaaatatt ctccgtctta ccagttttgg ggaatcgcac
     9001 ggtaagggtg tgggaggagt gatagacgga ttccctgcag gaatagtcat tgatatggat
     9061 ttcgtccagg cagagctcga ccgacgccgc cccggacagt cacgtatcac taccgcccgg
     9121 aaagaaggtg ataaagtgga gttcctctcc ggcatcttcg aaggaaaatc cacaggctgc
     9181 cccataggat tcattgtatg gaaccaaaac caacattctg acgattacaa taatctgaaa
     9241 gaagtctacc gaccgtcaca tgccgactat acttataaag tgaaatatgg catccgcgac
     9301 caccgcggag gtggacgttc atcagcccgt gaaacaatct cgcgtgtagt agcgggtgcc
     9361 ctggccaaat tggcgctgaa gcagctgggt atacacatca cggcgtacac ttcacaagta
     9421 ggtcctatcc gccttgaaga aaattatacc gcatacgacc tcgacctgat agagaccaat
     9481 ccggtccgct gccccgaccc ggcgaaggca aaagaaatgg aagaactcat cttcaagata
     9541 aagggagaag gagataccat cggaggagtg gtgacttgtg tcgtcaaagg atgccccatc
     9601 ggactgggac aacccgtatt cggcaagctc catgcagcac ttggagcagc catgctcagc
     9661 atcaatgcag caaaagcatt cgagtatgga gacggtttca agggattaaa gcagaaaggc
     9721 tcggagcaga atgatgtgtt ctacaacaat aacggacgta tcgagacccg caccaatcat
     9781 tcgggcggta tacaaggtgg aatcagtaac gggcaagaca tctatttccg tgtagccttc
     9841 aaacccgtgg caaccgtact gatggagcaa cacaccgtga acattgacgg tgtagacacc
     9901 accctgaaag cccgaggacg ccatgacccg tgcgtattgc cacgcgcagt acccatcgtg
     9961 gaagcaatga cagcaatgac attgttggat tattacctga ttgacagaac aacacaacta
    10021 taatattcac ccatggaaat aaagaaatac atcaccgaga acgagcctaa aatgctggaa
    10081 gacttgttca gcctcattcg cattccaagc atcagtgcca aacccgagca tcacgacgat
    10141 atgcttgcct gcgccgaacg ctgggcacag ttgctgctcg aagccggagc ggatgaagcc
    10201 ctcgtaatgc cctccaaagg taacccgatt gtttttggac agaaaatcgt agacccggac
    10261 gccaagaccg tattggtata tgcccactac gacgtgatgc cagccgaacc tctcgaactt
    10321 tggaaaagcg acccctttga accggaaata cgcgacgaac atatctgggc acgtggtgct
    10381 gatgatgaca aagggcaatc tttcatacaa gtgaaagcgt ttgaatacct cgtacgcaac
    10441 gaactgctgc aaaccaacgt aaaattcatc ttcgaaggag aagaagaaat cggctcgccc
    10501 agcctggaaa gcttctgcca ggagcacaaa gagttgctga aagcagacgt cattctggtt
    10561 tcggacacca gcatgcttgg tgcagacctg ccttcactga ccaccggact gcgcggactg
    10621 gcctattggg aaatagaagt gaccggcccc aaccgcgacc tacacagcgg tcacttcggc
    10681 ggtgctgttg ccaaccccat caatgtactt tgccagataa tcagccaagt gacggacgca
    10741 gagggacgta tcaccgtacc gggcttctat gacgatgtgg aagaagttcc ccaaaccgag
    10801 cgcgacatga tagcccgcat tcctttcgac gaagagaaat acaaaaaggc tatccatgta
    10861 aaagcacttt tcggagagaa aggttacagt acgctggaac gtaacagttg ccgtccgtct
    10921 ttcgacgtat gcggcatctg gggcggatat acgggtgaag ggtccaagac cgtgctccca
    10981 tccaaggcat acgccaaggt atcctgccgg ttggttcccc accaggacca ccacaagata
    11041 tcccggctct ttgccgacta cattctggac atagcgccgg attcagtaca ggtaaaagtc
    11101 actccgatgc atggaggcca aggatatgta tgtcccatca ccctacccgc ctaccaagcc
    11161 gccgaaaaag gttttgaaaa agcttttgga aagaaaccgc tggcagtgcg tcggggtgga
    11221 agtatcccca tcatctccac tttcgagcaa gtactgggca tcaaaaccgt tctgatgggc
    11281 ttcgggctcg aatccaacgc catccactca cctaatgaga atataccgtt ggacatcttc
    11341 cgtaaaggaa tagaagctgt tgtcgaattc tacctcaatt ataaataaaa caagaaaatc
    11401 aggatgaaag acttccaaat tcaagccatc ggcctgatgt ccggcacttc ccttgacggg
    11461 ctggacgtat gttgttgcac tttccggcag caagccggaa aatggtcttt ccacatagac
    11521 tgtgcaaaag gctatagcta ccccgacgcc atgaagcaga tattgggtac cggtgcacag
    11581 acaatgagtg ctttggagtt catcactttc cacagctcct atggaaagtt tctcggtgaa
    11641 cgtgtcaacg agttcatgca agaatttgga gtccaccccg atattatcgc ctcccacggg
    11701 cataccatct tccatgagcc tcaaaagaga atcatgtacc aaataggtga cggagccgcc
    11761 attgccgctg aaacccgtat acctaccgtt tcggatttcc ggcggctgga catcatgctg
    11821 ggtgggcagg gcgctccact cgtacctatt ggcgaccggt tgctttttgc cgactacgac
    11881 ttctgtttga atatcggcgg tttctccaac atctcattcg agcaggacgg gcggcgcatc
    11941 gcttttgaca tcagtccggt gaattacgtc atcaaccatt actgccggca aataggattg
    12001 gaatttgacc gtgacggcga gatagcacgg caaggcaaca tctgccaaga actgctggac
    12061 gaactgaacg gaatggattt ctaccatcag tccggaccga agtcattggg acgggagtgg
    12121 gtggaaacgc tggtatatcc catgctcgag cgttatggct tgagtatgga gaatatgcta
    12181 cgtacctttt acgagcatgc cgcctggcaa atatcacgca tcatcaccgc ccgccccttg
    12241 cccgatggta acggaaaact gctgattacc ggcggaggtg cattcaacaa gttcctcata
    12301 gaacgtatcg acgccttgtg tccgtgtgaa atcgtgattc ccagccggca aatcatagaa
    12361 tacaaggaag ccctaatctt tgctttcctg ggtgccctct atatggcgga cacacccgga
    12421 tgcctcgcct cggtgacggg agccacgaca gataatatcg gagggatgct gtttaaaata
    12481 tagtcaattc taccattatg gaaaaatcaa aagacacctg gaccgtctta tccagcgaat
    12541 accttcatcg ggccccatgg ctcactgtgc gtaaggacca tgtagtactg cccaacggca
    12601 accacattcc ctcctattat atattggaat atcccaactg ggtgaatacc attgccatca
    12661 cccgtgacgg acaattcgtc tttatccgcc aataccggca tggcatacaa gaaacatcct
    12721 atgaactctg tgcaggggta tgcgaagaag aggacggctc tccgatggtt tccgcacaac
    12781 gggaactttt ggaagaaacc ggctatggaa acggagtatg gaaagagttc atgcaaatct
    12841 ctcccaatcc aagtacccac accaacatta cctactgttt cctggctacg gacgtggaga
    12901 aaatctccga gcaacagttg gaagatacgg aaaacctgac cgtacacctg ctttccttgc
    12961 aggaggtcaa ggaattgctg cagcaaggaa gcatccgcca ggcgctgatg gctgctcccc
    13021 tctggaaata catggcggag agaattattt aatgtgatta cccttattca aacggcttac
    13081 ggaatgtgca tccggatttc cattcggaac aaccgtaagc cgttttcccc ttgataacgg
    13141 taccttttcc gcaaagcgga caaggctgac cgacgaaatc gtcagcttgt acggaagcct
    13201 ccgtacttga agctgccaca gcgcccgaag cctgctccgt ctttttacct gcggcggcag
    13261 actttctcgg tgttcttttc ttcggctcct ttttcggctt atcggcagcc tctgtcttgg
    13321 cagaagcctt actgcccttt tcgggagcag gcgcttggat ggtgatgtgg cggttgctgt
    13381 tatcagaaag tacactcatc acgacttccg ataccatctg cttcaattct tccaagaatt
    13441 gtccggcatt gtaagttcgt ttttctatct cacgcagttt cttctcccaa ataccggtca
    13501 gttccgccga cttcaacagc tcctcatgga taatctgtat cagctccaca ccggtaggag
    13561 tggctatcag gttcttcttt tccttgcgga tatagtttcg tttgaacagc gtctcgatga
    13621 tggctgcacg ggtagacgga cgaccgatac cattttcctt cagcgcatca cgcagttcgt
    13681 cgttatccac cagcttgccc gccgtttcca tagcacgcag cagggtggct tccgtataag
    13741 gccggggcgg ctgcgtccac ttctcatata aatcgggaac gtgcggcccg ctttctcctt
    13801 tcacaaaagc cggaagcaca ttctcctctt ctcccttttc ctctttctcc tcctgcgatt
    13861 gtgccgaggg ggcgccgaag ataacacgcc aacccggttc cagaatctgc ttgccggtgg
    13921 ccttgaactc tatgctctct acctcgccca atacggtggt agtggcaaac ttacaatcgg
    13981 gatagaatac agcaatgaaa cggcgtgcta tcaaatcgaa tacgcgacgc tccatatccg
    14041 tcagattctg cggatgctgg ccggtaggaa taatggcgtg gtggtctgtt accttcgagt
    14101 tatcgaaaac ctttttggac ttcaacaatg cagttcctgt caaaggggct gtaaatgtct
    14161 cgtaatcacg cagacctttc aagatgccgg ggcatttggg atagatgtca tcactcaaat
    14221 aggtagtgtc tacacgtgga taggtagcca ctttcttctc atacaaagac tggatgattt
    14281 tcagcgtctc atcagcggaa taggcaaact tcttgttaca ttccacttgc aaagaagtca
    14341 agtcaaacaa gcggagtggc gcctccctcc cctctttctt ggtgacatcc gtcacggtaa
    14401 aaagagaatt cttaatctgg tccaataaaa caagcccacg ttcgcggtcg gtaatggggt
    14461 cgataccccg attctcttct tcttttttag gtttcttccc ggcagctata gcctctttct
    14521 gcttctcggc ttccaatacc agttcctcct cacttttccg gaggatggtg gagaaagtgg
    14581 tatctcgata gacggtcttc agttcccagt attgcttggg aacaaaattc tgtatttcca
    14641 actgacggtt tacaatcagc gccagtgtcg gcgtttgcac acggccgata gaaagtacct
    14701 gccggttctg cccatacttc atggtgtaga ggcgggtggc attcatcccg agcagccagt
    14761 cgccaatggc acgcgacaag cctgcttcgt acaaaggctg gaaatccgac g
//
