LOCUS       c00102_gnlPro..        12942 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKHBJOCE_102.
ACCESSION   c00102_gnlPro..
VERSION     c00102_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 09:38:47
            Original ID  :: gnl|Prokka|JKHBJOCE_102
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12942
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12942
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2942]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..2942
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..12942
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12942
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(3..569)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_1"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4.2e-61,
                     bitscore: 196.3, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGVLIALIPAFLVSLYFFGLGALIVTATSVAACLFFEWAIGKFL
                     LKKETTTICDGSAVITGVLLAFNLPSNLPIWIIILGALFAIGVGKMSFGGLGCNPFNPA
                     LAGRVFLLLSFPVQMTSWPVVGQLTSYTDATTAATPLNLMKQIAGGNIEALKDLPSSFD
                     LLIGNNGGCLGEVSALALLLGLAYML"
     CDS             complement(642..1979)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_2"
                     /sec_met_domain="Fer4_10 (E-value: 1.7e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 3.6e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 9.3e-50, bitscore:
                     158.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.2e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVTAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             complement(2040..2942)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.5e-12, bitscore: 37.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.3e-10, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 4.5e-09, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 4.7e-09, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1e-11, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.3e-06, bitscore: 16.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCGYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRVYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDAA
                     PQVKVAAPKAEVETPKAEV"
     CDS             complement(2980..3399)
                     /locus_tag="ctg102_4"
                     /transl_table=11
                     /translation="MANTIKHQGIVENINGSHLQVRIIQTSACASCSVKGHCTSADTKE
                     KLVDVADADAASYQPGDRVWVTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELR
                     SALCSLALLVPYYYILWLNKSRMGKKFSFSVRPMN"
     CDS             complement(3630..5030)
                     /locus_tag="ctg102_5"
                     /transl_table=11
                     /translation="MISSSVMAQNTLDTASKNSGQETTAKADTLPDIMKEYMILKLKPE
                     GMGYRLDTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYYAPMRRLSKV
                     DWHFQVPDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVNCPNLVVMTEKEVMK
                     GKIFKDNIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNGSLQITQNYI
                     SDNWYKGGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEFHNYLVSTDQ
                     LRLYSKLGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSSSIGMDYKLK
                     KQKFSLSVFMAPLTYMLRYVGNKGVNEVSFGLDEGKCVKHNFGSQIQPTLSWTIIPSIT
                     LDSRLDFQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGDSYFQVKELL
                     SFGINYKW"
     CDS             complement(5102..5308)
                     /locus_tag="ctg102_6"
                     /transl_table=11
                     /translation="MPRAYTACRSRCILLPSVHVELKKRKIIKKRGSRESFDETIIKKY
                     DFIEESPSCLFLMAFLCFLNILS"
     CDS             5340..6959
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg102_7"
                     /sec_met_domain="GATase (E-value: 6.5e-55, bitscore: 175.4,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGKDALCVHLTYVPYLAAAGELKTKPTQHSVKELQSAGIQPDVLVLRTEHELSTTL
                     RKKVALFCNVDENAVVQSIDAPTIYEVPILMQSQGLDVTILKKMGLPVGDTPGLGPWRA
                     FLERRHKAEETAPLHIALVGKYDLQDAYKSIREALSQAGTYNDRKVSVDFVNSEKLTDE
                     NVAEALKGMAGVLIGPGFGERGVAGKFVAIKYARTHDIPTFGICLGMQCIAIEFARNVL
                     GYADANSREMDEKTPHNVIDIMEEQKSITNMGGTMRLGAYECVLQKGSKAYEAYGTEHI
                     QERHRHRYEFNNSFKDAYEAAGMKCVGINPESDLVEIVEIPALKWFVGTQFHPEYSSTV
                     LHPHPLFVAFVKAAIENENEKK"
     CDS             6991..8844
                     /locus_tag="ctg102_8"
                     /transl_table=11
                     /translation="MDKNTITGLVLIAILLVGFSFLSRPSQEQLEAQQRYYDSIAQVQQ
                     READLKAKAEAALANESGAEASVDSTALFFDARQGTNSQVTIQNNLAEITVDTKGGRIA
                     SATLKEYMGQDKTTPVTLFSGNDASMNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLS
                     ADSNSYIDFTYSMHNDTYLIDFTIQAVNMEGKLAATNNYVDIEWSQRARQIEKGYTYEN
                     RLAELTYKITGEGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSK
                     METQGSGYIKDYSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDDKWELNRLV
                     YLGWPLIRWINKWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMR
                     VLKPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVP
                     SAIELRQQSFLWADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQD
                     TGANPQMAAMKWMSYLMPVMFLFILNDYPSGLNYYYFISTLVSVVTTLIMRKTTNEEAL
                     LAQLEANKKDPKKMKKTGFAARLEAMQKQQEQMMKEKQNKK"
     CDS             8947..10278
                     /locus_tag="ctg102_9"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQMIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGERQYKEIGDLFYQGIYFQVGMAAVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCCKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFALFPKLILG
                     IYTDIPDLQDAAVHSLWVMCSTYLFLVPANVYFQAVSGTGNTRTALGMELATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             10340..12439
                     /locus_tag="ctg102_10"
                     /transl_table=11
                     /translation="MSAAMTLASCGGTKDAGQQQDAAVLIQRSDIKIEGKRMTPEALWA
                     MGRIGSVAVSPDEKQIAYTVSYYSVPQNKSNSEVFVMNADGSGNTQITHDAWQEGQPTW
                     FKDGKKLAFLCNESGSSQVWEMNPDGSGRKQLTQYEGDIEGFSFSPDGKKLLFIAQVKT
                     VKSTADKHPDLPKATGIIVTDLMYKHWDEWVTTAPHPFVADFDGNAISNVTDILEGEPY
                     ESPMKPWGGIEQLAWSPSSDKVAYTCRKKTGLAYAISTNSDIYIYDLASKETKNITEEN
                     KGYDTNPQYSPDGKYIAWQSMERDGYEADLNRLFIMNLETGEKRFVSKAFESNVDAFLW
                     NKDSRSIYFIGVWHGETQIYNIDLAGNDKLTQLTDGMYDYASLALCGDKIIAKRHSMSM
                     GDEIYAVNSARNGDAFAEAVQLTTENKQIYDQLEMGKVEARWMKTTDGKQMLTWVIYPP
                     QFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVAPNRRGLPGFGVEWNE
                     AISGDYGGQCMKDYFTAIDEMAKEPFVDKDRLGCVGASFGGFSVYWLAGHHDKRFKAFI
                     AHDGIFNMEMQYLETEEKWFANWDMGGAYWEKNNATAQRTFANSPHLFVDKWDTPILCI
                     HGEKDFRILANQAMAAFDAAVMRGVPAELLIYPDENHWVLKPQNGVLWQRTFFEWLDKW
                     LKPAK"
ORIGIN
        1 caaagcatat aagccaatcc caacagcaat gccaaggcac ttacttcacc caagcaacct
       61 ccattattac caatcaataa gtcaaaagaa gaaggcaaat cttttaaagc ttctatattt
      121 ccaccggcaa tctgcttcat caggttaaga ggtgtagccg ccgtcgttgc atctgtataa
      181 gaagtcaact gtccgacaac cggccagctc gtcatctgca cagggaaaga gagcaacagg
      241 aatacacggc ctgccaatgc ggggttgaac ggattacaac ccagtccgcc aaaagacatt
      301 ttaccgacac ctattgcaaa caatgcaccc agaataataa tccagatagg cagattggaa
      361 ggtaagttga atgccagcaa cacacctgtg attacggcag aaccgtcaca aatagtcgtg
      421 gtttctttct ttaaaaggaa tttgccgata gcccattcaa agaacaaaca ggcagctacc
      481 gaagtagccg taacaatcag cgcacccagt ccgaagaaat agagtgatac gagaaatgca
      541 ggaatcaatg caatgagcac gccatacata ttctttttca cgctgtcacc accatggacg
      601 tggggcgaaa gtgatactat taatttattt tcaatacttc gttatttttt agcttgacgt
      661 gcacggatca tcgctcctac cttaccctta cccaagcgga tataatccag catcggacgg
      721 ttggaaggac aagtgaactg gcatgaaccg cattctatac acgacataat gtcttctttc
      781 tctactcttt caaaatctcc gtgggccgaa acggtagcca gcagatacgg ctccaacccc
      841 atcgggcagg ctcccacgca cttagcacaa cggatacaag gctgtacttc gccgcgcttg
      901 gcttccttct cgttcataat cagaataccg gagcttcctt tggctgtcgg tacatccgta
      961 tttaccagag ctttacccat catcgggcca ccgccgataa tcttgcccgt atcttcgggc
     1021 agaccgccgc aagcttcaat cagctgcttc atcggcgtac cgatacgtgc caggaaattg
     1081 gacggctttg ccaacgactt accagtcacg gtaatgacac gctcaaacag aggtttgttc
     1141 ttctgtacgg cctggtaaac ggcaaatgcg gtacccacat tctgcaccac agctcccgtg
     1201 gagataggca gcgcaccggc tgtaacctgg cgactgatga cagcatcaat caactgcttt
     1261 tcaccaccct gcggatattg taccttcaag ggtaccacct cgatacctgc atagctggaa
     1321 gcaaccttcg tcatcagctg gatggcatcg ggcttgttgt tctcaatgcc aatgaatgcc
     1381 ttgttcacct ttaccgcttt catcagaatg gatacaccta ccataatttc ttccgcatgt
     1441 tccagcatca gctgatggtc ggcagtcaga tacggttcgc actctacggc gttgatgatg
     1501 acacactctg ccttgaatgc aggaggagga cacaacttga cctgcgtagg aaagcatgca
     1561 ccgcccagac ctacgatacc ggcatcagcg attttcttca cgatttcctc ggaggtcaga
     1621 ctgcattcct tcaccaacgt ttcggaacgg tcaatggatt cttcccattc atccccttct
     1681 acgtcaatga atatagcagg cttggcgtaa ccgctggcat cgacaatcgt gtcaatctta
     1741 gcgactttcc cgctgacaga cgaatgaatg gctgctgata caaaaccgcc gggctcggca
     1801 atcttcgtac ccactttcac aacatcacct ttggcaacga taggcttggc aggagcaccg
     1861 atgtgctgtc ccagcaagat agcggccttg gccggaatct ctgccttgat gataggctga
     1921 tgtgctgaaa gtttattttc gtgtggatgg actccaccaa ttgaaaatgt cttcaacata
     1981 caattctgta tttttagtcg tttatttact ttattaattc atacctcaac ttgggaagtc
     2041 taaacctctg ctttgggagt ctcaacctca gctttaggag ctgcaacctt tacttgggga
     2101 gctgcatcgt cagccttcgg tttgcgcggc gggaagttga gggcaatgat tgtgttttgc
     2161 ggacaagctt cctcgcactt gcgacaggat ttgcacttat tggggtcaat gtaagccaga
     2221 ttgttttcca gcgtgatagc ctcgaacgga caaaccttca cacacttgcc gcaaccgata
     2281 catgccacgg tacaagcctt gcgtgctaca gcccccttgt ccttgtttac acactgtacg
     2341 taaacacgac gtgatttctt gccttgagga cggatttcaa tgatagattt cggacaagcc
     2401 ttggcacaag ctccacaagc cgtacacttt tcctcatcca cttcgggaag tccggtctcc
     2461 ggattcatgt ggatagcatc gaactggcag gcagccacac agtcgccgca tcccagacag
     2521 ccataaccac aacccgtttc accaccatag agagaagccg caatggcaca actcttggcg
     2581 ccatcgtatt ggttcacacg aggacggttg gcacaagttc cattacatct caccaccgca
     2641 accataggtt cggcagcagc ggcatccaag cccagaatct cggcaatctt tgtcatgacg
     2701 ggctgtccac ccaccggaca aagtttacca tccagcgaac ctgcctttac gcaagcatct
     2761 gcaaatccgc tacaaccggg gtaaccacat ccaccgcaat ttgcctgggg aagcacctct
     2821 gctacctggg caatccgcgg atcttcatac acggcgaatt tcttggaagc cacgtaaaga
     2881 atagcggccg ataccagcgc tataactccc aatgaaatca ctgcaatcag aattacattc
     2941 ataaattagt tgtttattaa ttatttgttt tattattagt tagttcatcg gtcgtacgga
     3001 gaatgagaac ttcttaccca tccgcgactt gttcagccac aatatataat aataaggtac
     3061 aagaagtgct agcgaacaaa gcgcggaacg cagctcgtca ttccagatag ccataaagac
     3121 aaacagtgag attatcagaa taaggaaagg aaatataaag gcaaacagaa ctgccatcac
     3181 tcccattgaa agttcgcccg tcacccatac acggtcgccg ggctggtagg atgcggcatc
     3241 ggcatcggcc acatcgacaa gtttctcttt cgtatccgca gaggtacaat gtcccttgac
     3301 actacacgaa gcgcatgctg aagtctggat gattctcact tggagatgag aaccgtttat
     3361 gttttccaca ataccttgat gttttatagt attcgccatt ttgcaaagtg tgcattacaa
     3421 atcgtggcaa atttacgcat tatttgtgaa ctgcaaacct ttcctatgta ttttctgtgt
     3481 tcgcaaacat gctttttcta tgtttttatg ttttttcacc tgccacagac tacaaaaaga
     3541 caaaaaacag acggtctgtc aagggaaaac agaccgtctg actaactaaa acagataatc
     3601 tgttcactcc gaacagacca tttgtttatt taccatttat aattgatacc gaaactgagc
     3661 aattctttta cctgaaaata gctgtcccct tccgtcggct tggcactgtc gtcatagcgg
     3721 gcgtgcacat agagcttggt ggaaagatag cggttcagca caaagttcac cgtgttttcc
     3781 cattcaatac gtgtccactc ataactggtc tggaagtcca agcgggaatc cagcgtgatg
     3841 gaaggaatga tggtccatga aagtgtaggc tgtatctgcg aaccgaagtt atgcttcacg
     3901 catttgccct catcaagacc gaaactcact tcattcaccc ccttatttcc tacatagcgc
     3961 agcatgtacg tcagcggagc catgaaaacg gacaagctga atttctgctt cttcaacttg
     4021 tagtccatac cgatactgct cgaccagtct gccggagcaa agaaagccga aaccagctct
     4081 tcactgttgg ccttgtagcc attgcagaac tgggtcttaa actcagtcgt gatggtataa
     4141 taccacttgg acgcagcctg aatacccagt ttactgtaca gccggagttg gtcggtactt
     4201 accagatagt tatgaaactc gtcggaaggt gcggagctga agcccagctt ggcatcgagc
     4261 agattttccc actgcacctt ttcacggtca ttatagttgg caaacaattg caggttggca
     4321 agcacggcgt tagtgctctc acctcccttg taccagttgt cggagatata gttctgggta
     4381 atctgcaatg aaccgtttcc acccgtcacc caccagttgg gcttgtggat aatcacgtcg
     4441 gcttcctcct tcactcccac catattctct tgtgcaaaca gtttcacgac ggacggcttg
     4501 gaagaaacct ccttctctat attatccttg aatatcttcc ctttcatcac ctccttctcg
     4561 gtcattacaa ccagattggg acaattcaca tacgtgttca gcagcgtacg gtccaccagt
     4621 ttgttggctc ggtcctttga ggtgaaactc agtgtgtcga acggcaacat ctcgcgcgtc
     4681 agggcaggca ccgtatcagg cacctggaaa tgccagtcca ccttggaaag gcgtctcatg
     4741 ggggcataat aataggtaag gggaaggaac aacctatagt agttcggatt ggaaggtata
     4801 taacgctccg gagtcgtggg gtcattcaaa taatccagca ctccgatata cctttcatat
     4861 aatatggaaa cagtatccag cctgtacccc ataccttccg gtttcaattt cagaatcatg
     4921 tattctttca ttatatccgg caaggtgtcg gctttggcag ttgtttcctg tccactgttc
     4981 ttcgaggcgg tatccagcgt attctgtgcc atcaccgacg aagaaatcat cgtagcaatt
     5041 aaccaaaatg caatgtgtct attcttcata atgccctaaa gtctatgttt cgagcgcaaa
     5101 tttagcttaa aatgtttaga aaacatagaa aagccataag aaaaaggcaa gaaggacttt
     5161 cttcgatgaa atcgtatttt ttaataattg tttcatcgaa actttctcta cttcctcttt
     5221 tttttataat tttgcgcttt ttaagttcta cgtgtactga cgggagcagt atgcaccttg
     5281 aacgacaagc cgtataggct cttggcatta gattaaacaa ttaataaaat aatatagttg
     5341 tgggagaaac aaagtatatt ttcgtcaccg gtggtgttgc ctcttcatta ggtaaaggta
     5401 tcatctcatc ctccatcggt aaattgctgc aagcaagagg ttacaaggta accatccaga
     5461 agtttgaccc gtacatcaac atcgacccgg gtacactgaa cccttatgaa cacggcgaat
     5521 gctacgttac cgtggatggc cacgaagccg acctcgattt gggccattac gaacgcttcc
     5581 tgggcatcca gaccaccaag gccaacaata tcacgaccgg acgcatctac aaaagcgtca
     5641 tcgacaaaga gcgccggggt gactatctgg gaaagaccat ccaggttatt ccccatatta
     5701 cagacgaaat caagcgtaat gtaaaactgc tgggaaacaa atacaaattc gactttgtta
     5761 ttaccgagat tggcggtaca gtgggtgaca tcgagtctct gccctatctg gaaagcatcc
     5821 gtcagctgaa gtgggaactg ggaaaagacg ccttgtgcgt acaccttact tatgtcccct
     5881 acctggcagc tgccggtgag ctgaagacca agcccaccca gcactccgta aaggaactgc
     5941 aaagtgccgg tatccaaccc gatgtcctcg tactgcgtac ggagcacgag ttgagcacta
     6001 ccctgcgcaa gaaggtggct ctgttctgca atgtggacga gaatgccgtg gtgcagagca
     6061 tcgacgcgcc taccatctac gaggtgccca tcttgatgca gagccaggga ctggacgtta
     6121 ccattttgaa gaaaatggga cttcccgtcg gtgatactcc gggactggga ccgtggcgtg
     6181 ctttcctcga acgccgtcac aaagccgaag agactgcccc actgcacatc gcattggtgg
     6241 gcaaatatga cttgcaggat gcctacaagt ccatccgcga ggccctttca caagcaggaa
     6301 cctacaatga ccgcaaagta tcggtagact tcgtgaacag tgaaaagctg actgacgaga
     6361 atgtggcaga agccctgaaa ggcatggcag gcgtacttat cggtccaggc ttcggcgaac
     6421 gcggcgttgc cggcaagttc gtagccatca aatatgcgcg tacgcacgac atccccacct
     6481 tcggtatctg tctgggtatg cagtgtatcg ccatcgaatt tgcccgtaac gtactgggtt
     6541 atgccgatgc caactcacgc gagatggacg aaaagacacc gcacaatgtc atcgacatca
     6601 tggaagagca gaagtccatc accaatatgg gtggaaccat gcgtctgggt gcctacgaat
     6661 gtgttctgca gaaaggcagc aaggcatacg aggcatatgg taccgagcat atccaggaac
     6721 gtcaccgtca ccgctacgag ttcaacaaca gcttcaagga tgcctacgaa gcagcaggca
     6781 tgaagtgtgt gggtataaac cccgaatcgg acctggtgga aattgttgag attcccgcat
     6841 tgaagtggtt tgtcggtacc cagttccatc ccgaatacag cagtacggta ttgcatccgc
     6901 acccactgtt cgtagcattc gtgaaggccg ccatcgaaaa tgaaaacgaa aagaaataat
     6961 ttgtaataag taatttgtaa tcaacaaaga atggataaaa ataccatcac aggtcttgtt
     7021 ctgatagcga tattgttagt aggtttcagc tttctgagcc gtcccagcca ggagcagttg
     7081 gaagcacagc aacgttacta cgactccata gcccaggtgc aacagcgcga agccgacttg
     7141 aaagccaagg cggaagcagc cctggccaac gaaagcggag cggaagcaag cgttgactcc
     7201 actgccctct tcttcgacgc ccgtcaagga accaactcgc aggtaaccat ccagaacaac
     7261 ctggcagaaa taaccgtaga tacaaaaggc gggcgcatag cttcggccac gctgaaggaa
     7321 tacatgggac aagacaagac gacccccgtc acactgttca gcggcaatga cgcctccatg
     7381 aatttcctct tttacaacaa gaaagagact atccagacgg aagactatta tttcaccgca
     7441 gtaaaccgta cggacagtac cgtcaccatg cgtttgtcgg cagacagcaa cagctatatc
     7501 gactttacct acagcatgca caatgacaca tacctgatag actttactat ccaggcagtc
     7561 aatatggaag gcaagctggc ggctaccaac aattatgtgg acatcgagtg gtctcagcgt
     7621 gcccgtcaga tagagaaggg ttacacctac gagaaccgtc tggctgaact gacttacaaa
     7681 atcaccggag agggtaccga ttatctgtcc gccaacaaga acgacgaaaa ggaagttccg
     7741 gaacgcctgg actggattgc tttcaagaac cagttcttct cttcagtatt tttggcagat
     7801 gccgactttg aaaagaccaa actgagttcc aagatggaga ctcaaggcag cggctacatc
     7861 aaggactatt ctgcggagat gagcacgaag ttcgaccctg ccggcaagga acctacccag
     7921 ctgttcttct acttcggccc caatcactac aagactctga ccgcactcga caagggacgt
     7981 gacgataagt gggagctgaa ccgtctggtc tatctgggct ggccgctcat ccgctggata
     8041 aacaaatggt tcaccatcaa catcttcgac tggttgtcca gttggggttt gagcatgggt
     8101 atcgtactgt tgttcatgac gctgattgta aaggcagtgg tattcccggc tacgtggaag
     8161 acctacatgt cttctgccaa gatgcgcgta ctgaaaccga aaatcgacga gataaacaag
     8221 aagtacccca agcaggaaga tgccatgaag aagcagcagg aagtgatggg cctctacagc
     8281 cagtacggag tcagcccgat gggcggatgt ctgccgatgc tgatacagtt ccctatcctg
     8341 atggccttgt tcatgttcgt gccgagtgcc attgaactcc gccaacagag cttcttatgg
     8401 gcagacgacc tttccactta tgatgcgttc atcaacttcc cgttccatat cccgttcctg
     8461 ggcagccacc tcagcttgtt ctgcctgctg atgacggtta ccaacatatt gaacacgaag
     8521 tacatgatgc agcagcagga tacgggtgcc aatccgcaga tggctgccat gaagtggatg
     8581 tcatacctga tgcctgtcat gttcctcttc atattgaacg actatccttc gggattgaac
     8641 tattactact tcatctctac gttagtcagt gtggtaacaa cgctcatcat gcgcaagaca
     8701 accaatgagg aagcccttct tgctcagttg gaagccaaca agaaagaccc gaagaagatg
     8761 aagaaaaccg gtttcgccgc tcgtctggaa gccatgcaga aacagcagga acagatgatg
     8821 aaagaaaaac agaacaaaaa gtagtaagac taccgttcaa gatattcttt tgcagaaagc
     8881 cggacaatga catttgcccg gctttcttat ccttacacca acgaaaaaat tcacagactc
     8941 taaattatgc agactaaata cacttacaaa caaatctggc tcatagccta ccctatccta
     9001 atcagcctcc ttatggagca gatgataggt atgacggaca ccgccttcct cggacgtgta
     9061 ggtgaagtcg agttgggagc atctgccatc gccggtgtct tctatatggt catcttcatg
     9121 gttgccttcg gtttcagcat cggggcacag atactcattg cccggcgcaa cggcgaacgg
     9181 cagtataagg aaatcggtga cttgttctat cagggcatct atttccaagt cgggatggcg
     9241 gcagtcatgt tcctgctatc ttattgcttc tcgccgatta tcctgaaacg catcgtagcc
     9301 tcggaacata tctacgaagc agccaccagc tacctgcact ggcgtgtatt cggtgccttc
     9361 ttctcgttca gcgcagtcat gttccgtgcc tttttcttgg gaaccaccca gaccaagaca
     9421 ctgacactga actccatcgt catggtgttg agcaatgtcg tattcaacta tatcctgatt
     9481 ttcggtaaat tcggttttcc tgcactcggc attgccggag ccgccatcgg ctcctcattg
     9541 gccgagctgg tttcgctgtt attcttcatc ctctataccc gtagccgtat cgactgctgc
     9601 aagtacgggc tggaccgtat tccgaagttc cggctggacg tattgaaacg gatgctgaac
     9661 gtctctttct ggaccatgat acagaatttc ttctccctct ccacctggtt cttgttcttc
     9721 ctttatgtgg agcatctggg agagcgatcg ctggcagtga ccaacattgt ccgcaatgtg
     9781 tccggcatac tgttcatggt actcatggca tttgcctcta cctgcggttc attggtcagc
     9841 aacctcatcg gtgcaggcca ctccgattgc gtggcaggca ctatccggca gcacgtacgc
     9901 atagcctacg ttttcgtact tccgctggca ttgcttttcg cgctgttccc caagctgatt
     9961 ctgggaattt ataccgacat acccgacctg caggacgctg ccgtgcattc gctttgggtg
    10021 atgtgctcca cctatctgtt cctggttcct gccaatgtct atttccaggc agtttccgga
    10081 accggcaata cgcgtactgc attgggcatg gagctggcaa cgctggtcat ctacacagcc
    10141 tatatcacct acattattct gattctgcaa ctcgacgtgg ccatctgctg gacctcggaa
    10201 atggtttatt ccagctttat tctcattttc tgctggctat atatcaaacg tgggaattgg
    10261 caaggaagga aaatttagta tctttgcatt gaaataaccg aaacaaaaaa catatatgaa
    10321 acaagtaaat ctactactta tgtcagcagc catgacattg gcctcctgcg gaggaacaaa
    10381 agatgccgga cagcagcagg acgcagcagt gctcatccag cggtcggaca tcaagattga
    10441 aggaaagcgt atgacacccg aggcactctg ggcgatggga cgtatcggca gtgtagccgt
    10501 atctcccgac gaaaagcaaa ttgcctacac ggtatcctat tacagcgtgc cccagaacaa
    10561 gagtaacagc gaagtcttcg tcatgaatgc cgacggtagt ggcaataccc agataacgca
    10621 tgacgcctgg caagaaggac agcccacatg gttcaaggac ggcaagaagc ttgccttcct
    10681 ttgcaacgaa agcggcagca gccaggtatg ggaaatgaat cccgacggca gcggacgcaa
    10741 gcagctgacc caatacgagg gagacatcga agggttctct ttctcgcccg acggcaagaa
    10801 actccttttc attgcccagg taaagaccgt gaagagtacg gcagacaaac atccggacct
    10861 tcctaaagcc accggcatca tcgttaccga cctgatgtac aagcattggg acgaatgggt
    10921 gactactgct ccccatccgt ttgttgctga tttcgacggc aatgccatca gcaatgtcac
    10981 tgatattctt gagggagagc catacgaaag cccgatgaag ccctggggcg gtatcgagca
    11041 gctggcatgg agcccgtctt ctgataaggt ggcctataca tgccgtaaga aaaccggact
    11101 ggcgtatgcc atttccacca actccgacat ttatatctac gaccttgcct ccaaggaaac
    11161 caaaaacatc acggaagaaa acaagggata tgatacgaat ccccaatact ctcccgacgg
    11221 caaatacatc gcctggcaga gcatggagcg tgacggctac gaagccgact tgaaccgctt
    11281 gtttatcatg aacctcgaga ccggcgagaa acgttttgta agcaaagctt tcgaatcgaa
    11341 cgtggacgcc ttcttgtgga acaaagattc ccggagcatc tacttcatcg gtgtatggca
    11401 tggcgagaca cagatttaca acatcgacct tgccggaaac gacaagctta cccagctcac
    11461 cgacggcatg tacgactatg cttcgcttgc cctttgcgga gacaagatta tcgccaaacg
    11521 ccactccatg agcatgggcg acgaaatcta tgccgtaaac agtgcacgca acggcgacgc
    11581 ttttgcagaa gcagtgcaac tgaccacaga aaacaagcag atttacgacc agctggagat
    11641 gggtaaggtg gaagcccgct ggatgaagac caccgacggc aagcagatgc tgacctgggt
    11701 gatttatcct ccgcagttcg accctaacaa gaagtacccc accctcctct tctgtgaagg
    11761 cggtcctcag agtcccgtca gccagttctg gagctaccgt tggaatttcc agattatggc
    11821 agcaaacgac tatatcatcg tagctcccaa ccgccgtggt cttcctggct tcggtgtaga
    11881 atggaacgaa gccatcagcg gtgattacgg cggccagtgc atgaaagact acttcactgc
    11941 cattgacgaa atggccaagg aacctttcgt tgacaaagac cgcctgggtt gcgtaggtgc
    12001 cagcttcgga ggtttctccg tatattggct tgccggacac catgacaaac gcttcaaggc
    12061 attcatcgca cacgacggta tcttcaacat ggaaatgcaa tatctggaaa cggaagagaa
    12121 atggtttgcc aactgggata tgggcggcgc ttattgggaa aagaacaacg ctacggcaca
    12181 acgcactttc gccaactccc cgcacctctt cgtcgacaaa tgggacaccc ctatcctctg
    12241 catccacgga gagaaggact tccgcatcct tgccaaccag gcaatggccg ccttcgatgc
    12301 agccgtgatg cgtggcgttc ctgccgaact gcttatctat ccggacgaaa accactgggt
    12361 actgaaacct cagaatggcg tgctgtggca acgtaccttc tttgaatggc tggacaaatg
    12421 gttgaagccg gctaagtaaa gcccctcaaa aacgataaaa acaaatagtc ccggattctt
    12481 tgtcaagaat ccgggactat ttgtttttat tgtacaccgc ccgattcatt ttttatgact
    12541 ataatttggg cagttcaaat aaagtcaata catttgcttt atgcacactc cgaagaagtg
    12601 taaacaatat gtcctaatat aacccgataa aagatgaatg aaaattggcc tgagattgtg
    12661 gaaacactga taccgtattt tgaaacaaat tcggtagaag gtgactacca gcgggaaata
    12721 gagaactgct tgaaatttct tggatggaag aagaccaatg gaacaatggt atcccaatat
    12781 acattaccga taggcaatag caactccata cgcccggaca ttgtactttg gcgaaagaac
    12841 gagcatgaca cacaatcccc cgtactccct attgaaataa agcgtccgtc taatatacga
    12901 aatgaaagac aagaaaatca actgatgtcg tatatgcgcc ag
//
