LOCUS       gnlProkkaKPBOBNBH_19   16728 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KPBOBNBH_19.
ACCESSION   gnlProkkaKPBOBNBH_19
VERSION     gnlProkkaKPBOBNBH_19
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 23:38:18
            Original ID  :: gnl|Prokka|KPBOBNBH_19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16728
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16728
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6461:6728]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6462..6728
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..16728
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16728
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             310..636
                     /locus_tag="ctg19_1"
                     /transl_table=11
                     /translation="MKNCYGIDFRSWHKELRTREKTKQPPCKLPDRASRSLQGVLFKVY
                     QISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVRSDNSP
                     NSYK"
     CDS             1002..1217
                     /locus_tag="ctg19_2"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             1231..4809
                     /locus_tag="ctg19_3"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGWKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILTVASNGSKEITASFTASND
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVDAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLTFN
                     TAPTTSTAAPLTLTDKTNTSVSAPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGDTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKANANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTELMKLNITSG
                     TFNGDLKVDASVRTENAQSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTKLA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGYGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVGDGRKEYIVGQTSQENR"
     CDS             5056..5982
                     /locus_tag="ctg19_4"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             6009..6449
                     /locus_tag="ctg19_5"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             6462..6728
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_6"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.3e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.1e-15, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             6737..7900
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_7"
                     /sec_met_domain="NTP_transf_5 (E-value: 5.2e-46, bitscore:
                     148.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRYFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             7923..9566
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 249.3; E-value:
                     1.3e-75)"
                     /gene_kind="transport"
                     /locus_tag="ctg19_8"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFRYTPDDRPVFSRFSCRFPAGSCIAIVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETNHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASQEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLXXXXKTCAETAQAKHVSSSPTIRQ"
     CDS             complement(9643..10521)
                     /locus_tag="ctg19_9"
                     /transl_table=11
                     /translation="MGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGFGKLVFVIRKDF
                     EQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAVMMGADVIKEPF
                     AVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGTVSRGLCGTDAN
                     NLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDYFAYSAEFFKSF
                     LSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPEDRQSVVDKIQAL
                     VDAGEYPAKLF"
     CDS             complement(10680..13034)
                     /locus_tag="ctg19_10"
                     /transl_table=11
                     /translation="MKRLILYIAGLIFLAGCSTTKHLPEGEILYTGQKPMIVLNRSETS
                     VGEIAMEEVEAALATAPNNSLLGSSTIRYPFPFGLWIYNGFQKYEKGFGKWIFNKFAAT
                     PVLMSTVNPDIRQKAAVNLLRDYGYFNGSVSYKTFIDPKDSLKAKLQYTVNMRNPYFID
                     TVYYRGFSERTTRIMELGRRRSLISSGEQFNVADLDGERTRISTLLRNVGCYYFRPDYL
                     TYQADTMIVPNGHVQMRLIPVPGMPKVAEKQFRVGRKSVYLLGKQGQEPNDSMDYKGLT
                     IHYYNKPPVRPNMLYRWLNYQGYRRKRQIQDSAGIARQRSMQSLYSLYRQTRIQERLAS
                     VGIFRYAEMQYIPRDTAFVSDTLDVRVIAALDKPYDAELDFNVTMKSNNQTGPGAAFTV
                     TKNNVFGGGESWNVKLNGSYEWQTGKASSSLMNSYELGISTSLIFPRVVFPRMGDREYD
                     FPATTTFRLYADQMNRAKYYKLLAFGGNVTYDFQPKSTSRHSITPFRLTFNVLRNPTAA
                     FDTLRAENPALYVSLRDQFIPAMEYTYTYDNASVRGKRNPIWWQTTVASAGNLTSAVYR
                     IFGKPFSEEGKKLFGVPFAQFLKLNSEFRYHYRIDKNQMIASRIAGGVIWSYGNATTAP
                     YTEQFYIGGANSVRAFSARSIGPGGYPPETDRKYTYINHVGDIRIEANIEYRFRMIADL
                     HGAVFLDAGNVWLMRKDENRPNGEFTLKNFPKQIALGTGFGLRYDLDFLVFRLDLGIGL
                     HDPYDTGKSGYYNIPKFKDSMALHFAIGYPF"
ORIGIN
        1 caaacgattg ctttatggtc gaaagcaggg ttgttcatgg ccgttaggcg tcataaattc
       61 cctatgccac agcagacaaa caaagggaga agagtaaagg aatacctatg ttttagataa
      121 aaatccacaa gctttcactc gtgctctcca taggttatga gagcaggctt cgcgctctgt
      181 gcgataaatt cccatttatc agcaggcata ctnnnnnnnn nnnnnnnnnn nnnnnnactt
      241 caattactta tataaattgt ttcagccaaa ggcagtacgg acatttgcaa aaatatggaa
      301 agtcttatta tgaaaaattg ctatggcatc gacttccgtt cgtggcataa ggagctacgt
      361 acacgcgaga aaaccaagca gccaccctgc aaactgccgg acagagcaag ccggagtttg
      421 cagggtgttc tgtttaaagt atatcaaatc tctgttttaa ttttgcttaa aaagatttta
      481 ttcagcttct tttcggtctg tcttcccctc tttattcgcc acatagccgc tatgctcctc
      541 agaaaaacat cctcaaagac aatgcagaca gttactaaat atttgaagga gttatcggga
      601 gttagaagtg ataactctcc taactcctat aaatgaaaga gacgtgagcc tttcccaaaa
      661 aaaatagaga aacatagata cacttaaaca aaaaacaatt atctttgtca caaatccgct
      721 atagcgtagt gggtttattt acatattagt aagagcatta ttgaaattat cttctttatt
      781 caaacttcgc aactttgaaa atttccctga agataacaac aaggatgctc acgtctatgt
      841 ttatatggtt ttctcccatc aggggggata gtatatacac aaacgacgtg agtgactgtt
      901 gtatatccag ggaaagggca atgcgaaggc ctgaataaag gatatacaaa catagttact
      961 cacgtttttt ttattgttta acctttaaat aatttgtgta tatgaaacag aacacaccag
     1021 acggtagaga agcatacatc actccgtcta tcgaagttat caaaatggag aatgaaggag
     1081 tcattgcaac aagcggcgaa ccttaccatc ccattacgcg ctcctattcg ggcagcacct
     1141 ctacccatag ctacaattcg gcatccagca gcgacttgga agacctaatc aatgacatct
     1201 taaccgtaga aaactaaggg ggacttcatt atgatgaaat taagaaacct tatgcaagtt
     1261 gcctgcatgg caactgctgc cttgaccgca ttcagttgca gccaagagga atttgaaaac
     1321 agcgggtgga aaggaaacat caccgttaac gcaacgtttg aaggcgcagg taccgacacc
     1381 cgtactaccg taaacgatga atacaagatt ctatggcaag ataccgatgc cctagggttg
     1441 ttctgtagta atgcagaaag taattatagc aatacaaaat tagaatatgc aagcggtgct
     1501 ggtcaaactt ccgccacttt caacggcagc aagccaagcg gagaaacggc tgtattctcc
     1561 atctatcctt accaacaaaa catgagcgta agcggcaata cattgaccat gactctacct
     1621 gccacgctta caaattataa cggcagcagc aatggcccga tgtatgccaa ggtgacaaat
     1681 cccgacaatc tgagcgctct gtccttcaag cacatggcag ccatgataaa actgaccgtc
     1741 aacaagattc cggcagaggc cactactttc aagattattg cctccaataa cattgcaggt
     1801 acttgtacgg tagacttaac cgcagcagac ccgatactga cggtagcaag caatggaagc
     1861 aaggaaatca ctgcctcctt cactgcttca aacgatataa aatcgcgcaa cttctacatt
     1921 cctttgccca caggtactta tagttccatc actgcccaac tgacgaatgg aagcgacaag
     1981 gtatatttta ccaagacgct taatgacaaa atcttaggga gaagagacat attggtagta
     2041 cctcctttgg attgcgttgt tgtagatgct acaaccccca gtgcgcttag tacagcttta
     2101 gctgattcaa aaaatctccc acaagaagca ccgacagcag caaccgtaac cgacattgca
     2161 gtcagcggca gcttcaatac cacttctggc agcaacgacg gcatcgccat cccggtttta
     2221 cagaactcgg acatcaacct gacgttcaat acagccccaa cgaccagtac tgccgctccg
     2281 ttgacgctga ccgacaagac caataccagc gtaagtgctc ccgccgccac tgccaccaac
     2341 agtgtatcct tggctgtacc ggaaaccaca gcagagcaag aagctccttc tgtagccatc
     2401 accatgccaa gcaccaccgt tacattggca gcagtaggca ataaagccac ttacaatgaa
     2461 gtgactgcca ctaccgccca gcagacattg attatcaatg caggcgtcac cgtaaagaag
     2521 ctgactgtaa aaggcggtaa cttgaagata tatggaaagg tagaacaatt ggtacacgat
     2581 gccggcgata ccacaatcta tataataaaa ggaactgaag catcacttcc ggcaacaatc
     2641 gacagcaaat ttgtagttca atccgacgtg gcagtcctaa agaccgcttt cgccaacggc
     2701 gaagatttta aattgtccgc cgatgccgac atcacagggc aaagcgtcag tgtacccgcc
     2761 ggaaagtccg tggttcttga cttgaacgga tatacactga ctgccgacaa cagcgcaaca
     2821 ggcaaaatca tcgtcttggg caagatgaca ctgaaggaca gctctaccga gaagaaaggc
     2881 aagatagttg ccagccagga ttatacagcg gcttcttata atggcagtct gattgaaata
     2941 gccggtgaag atgcctccat gaccatggaa agcggcaaca tcagtgcagt cagagagact
     3001 ccggacagta acggccaata tggcgtcgga gtgacggacg gtggagactt caccatgaca
     3061 ggcggcaaga tagaagccgg atggtttgca gtggcaggca acggcaatta caagacgcag
     3121 aactccatca tcaacatcac agacggagaa ctcatttcta ctgctgacta tgcagtctat
     3181 ctgccccaat ccggcacaac gaccatcagt ggcggcaagg tttatggtgc cgcaggaggt
     3241 gtatgcatcc aacgaggcac tctgaatgtg gaaggtacag ccttgattac cagtaaaggc
     3301 acaggtagca ccggcaactg gggcgacggt accggaggac tggactgcgc cgccatcaac
     3361 gtaagtggag catatggcat tgccacagta aacatcaaag gcggtacact gattgccgaa
     3421 gcaaagtcac tcatcacaga aggcaccact tatacaccgg tcatcaacgt taccggcggt
     3481 acattctccg acccaagcgc gctgaagtac atgaaggcaa atgcaaatgt gaacataaag
     3541 ttgaccgccg acaagacctg cccgggattc aagaccacaa gcggacaaac cttgacgatg
     3601 gacttaggcg gcaagattct tacacttgct gacccgaccg taggttccac cggcaccgaa
     3661 acgaacagct gtcaattact cgaaggttca aacgttactt tcaagaacgg aacgctgaag
     3721 agtgacaaca acaaaatcat gattcagaac tactgcaacc tgacattaga taatatgaca
     3781 gtagaagaca caaatgccca atacgtagta agcaacaatt gtggcaacat aagcatcaac
     3841 aataccacta tcaacgcagg aagcaatgcg aatcaatttg cattcgacgt atgcggctat
     3901 gcaaagtaca ctgctggagt cacggttacg gtaagcggta cgagcgtcat caatggaaaa
     3961 gtggaaattt ccaagagtgc aggaaatacc gaacttatga agctgaatat cacaagcggt
     4021 actttcaacg gtgacttaaa ggtagatgca tccgtgagaa ccgaaaatgc ccaaagtatc
     4081 atctctgttt ccggaggtac attctccgac ccaagcgtac tgaagtacat ggcaaccaac
     4141 gcaactgtgg atataaaact tctctcaaat atcaacatcg ccaagacgaa gcttgccaca
     4201 ggctacatat tgaatgctgc aaacgcaacg gcaaacttaa acctgaatgg ccacgacatc
     4261 atcaattcct cagaaacagc tgatgccact cctttcacac aaatctttac tgtacagaac
     4321 ggaacactaa acatttcagg caacggcaat gtgaagtgcg atgcatctgc tacagcgaaa
     4381 gacgatggtt atcgcatggt aattgaagcc cgaggatacg ggacagtaaa tattcatggt
     4441 ggttcttact ataacaccca gaaactgaac acccagatag acctgattta tgcaagagag
     4501 aatgggaaaa tcaatatcta tggaggaaca tttgaatccg gcaaatatgg tacacccaac
     4561 aacgacacgg atggcagata ctgggtactg aacttaaaga atacagacaa gaacactgcc
     4621 agcatccagg tgtccggtgg aacgttcatc aatttcaacc cggcaaatcc gaatatggac
     4681 gacaatgagt cctatttggt aacaggctac gaggttaccc gtgacggcag tgtatataca
     4741 gcagcccaca aagtcggtga tgggaggaaa gaatatattg ttggccaaac aagtcaggag
     4801 aaccgataag ccaaattcta agaaaggaag caatatatcc tcgcaaacca aacgaagaga
     4861 tatcggaatc gccttattac tatcttttag atgcggcgga cagcggattt tcttttatag
     4921 atctgcgtcc tccgcgtcta aagaatgaca acaagacagt tgaaaaatct ctcaaatctt
     4981 cctcattcac acaaacattc attatttttc tgagtagccc aaagtatcat gaataacaac
     5041 taacaatcaa aacatatgag aatacagata ttggattatc aagtaggacc gcacaccttt
     5101 cgcatggtga aaccttccga cttcaatata ttcaaggcgc tgccttcact gattccgttc
     5161 atcacgacaa tagacacgac gcaaaaagta atctttgaaa cagagataga cgatgacgaa
     5221 acaacgacaa aacgaaccat agcgaaaact cccgatgata tatgtttcaa ctgggaagat
     5281 gccgattgca tcattcgccc tttgccccac agctcacacc ttgtatccat caccccacgg
     5341 aaaagcggga aaaactattg gatggagtgc aacgataact tcaggcaatg cttcatccac
     5401 ctaccggcct gcaggacaga aacaccggct ccggaaaacg aaacgaactt cgtactgaac
     5461 aacttcttga tgatgctcta tgccttcaat gccgcccgcc accatacact gctgatgcat
     5521 gcctcggttg tcgctactga aacaggcaaa ggctacctct tcttagggaa aagcggcacg
     5581 ggcaaaagta cgcacaccgg gctctggctg caacagttct cggactgcca tctactgaac
     5641 gatgacaatc cgatagtaca tgtggacagc ctcggcaagc aagccactgt tttcggttct
     5701 ccgtggagcg gaaagacacc ttgctatcgg aaagaatcca tgaccgtagg cgccttcgtc
     5761 cgcttggaac aagcaccgca gaatgaaata gagcaagaga gagcagcaca tgctttcgcc
     5821 accctcctcc cctcctgctc ttgcctaaag cagaacaagg aaatctataa cgccattgtc
     5881 gccactgtga cggaacttgc cacgctggca cccgtctatc atctgaaatg cctacccgac
     5941 cgtgaagcga cggaactttg cagaaagacg gtagaaggat aagttatgaa tgatgaactg
     6001 aacagccgat gaagaaaagc attcccaacg agatattgct tcccgaagtg gcgcgtctca
     6061 tcaaagaggg acatacagta accatcaccg tgcggggcaa cagcatgaat cctttcttag
     6121 tggaccgccg tgaccgggtg acactgggcg atttcaccac agaacagctg caaccgggcg
     6181 tcaccgtact ggcacgcgac ctgacggaac gcatcgtctt tcaccgcatc atccgtcgga
     6241 acggagacat actcatcctg caaggcgacg gcaacctcgc ccagaccgaa gaaaccgaca
     6301 tcggacgggt aatgggcgtc atgaccgaag ccatgcgaaa agacaaacgg tacaccgccg
     6361 acggcaaagt ctggaagctc tactcctact ggtggatgaa gctaaacccc gctcgccgct
     6421 ggctgctcgc cctgttcaga agaatataaa acaaaataac catgaaaatc aaacaaggat
     6481 ttatcctgca ccggataggc gatgactaca tcatcatgca agacggctcg tcgaacgtgg
     6541 acttcagcaa agtcatcagc ctgaaccaaa cttccgccat gctttggcaa gagatagaaa
     6601 acaaagagtt cgatacagac agcgtgacag aagccctgac cagccgctat gatgtagata
     6661 acgaatcggc ccgtcgcgat gcgcagaagt ttatcgactc ccttgaccgc gaaggaatca
     6721 tagaataagg acggatatgc aacacgcttt cttttcattg gtacgctccg gcctgtgggg
     6781 cactccggca gaccgacaac tcttccggtc ggtctcgccg gacgactggg aaaccgtgta
     6841 ccgcatggca aactcacaag ccctgcttgc actgactttt gacggcataa gcagtctgcc
     6901 ggccgaactg cgccctccac gcgtcctcta tctgaaatgg gctgcccgga ctgcacagat
     6961 agaacaagcc aacaaacgcc tcaaccagct tctgcccgaa ctcaataccc tttaccggga
     7021 agccgggctg catcccgtac tgctgaaagg gcaaggcatc ggcaccaact accgcactcc
     7081 cttgcaccgg caatgcggag acatcgacat ctatttagga aaacaagggc aacccatagc
     7141 caaccgcctc ctgctgcaac aaggcgccat agtcgaggga gaagcgtccg acaagcatgc
     7201 tagctacagt ttgaaaggag tacacatcga gaaccaccgc atcatcctcc ggctgaacag
     7261 tccgcttgcc aaccggtact ttcagcagat tatcagaaaa tggtacccgc aggaaacaga
     7321 ctatgcccta ttctccgaaa ccgggaaaga ggactcgaag gccgtcagta tcgccatacc
     7381 tccggccacc ttcaatgcac tttatatctt cctgcatgcc tttgtacatt tcctgaacag
     7441 cggaatcggc ctgcgccagc tatgcgactg gacttgtctg cttgccaatc gccacaaaga
     7501 aatagatgcc accaccctgc ttcgccagtt gcaggacctc ggactattgc atgccgcaca
     7561 agcattcggc tacattgccg tcacccgact gggattgccc gccaaccggc ttcctttccc
     7621 cttggaaggc accaagcaga taggagaaca attattggaa gacatcctgt ctaccggtaa
     7681 cttcgggcaa catgataacc gcatcaagcc acgccccaaa ggatattggg caggaaagtg
     7741 gtacaccttc tgccgcgcca cccgacgctg caacgaactg cgtcaatttg caccgtacga
     7801 agcactctgg tatcccgtga ctctgatagg gggaacgata gctatacaaa taaaccgatc
     7861 aaaaggagta aaagacaaga aagcaaggac aaagaaataa aagaacccgg aaaataaaag
     7921 gaatgaaaaa gcaacagaag gacaaaaaag tgaaaaagga cagacgtgaa aaacttaggt
     7981 atattcgaga ggtatctgcc gaacaacgcg gacgtatcct gctaagttgc ctcaccggca
     8041 ttctgggcgt ggcctttgcc ctagccttta tctatgcaac caaacgggtg atagacaccg
     8101 ctaccggaat aacagacgac aacctgacgc atatcgccgt tctcaccgtt gtcctgctga
     8161 ctgcccaatt actgtgcgga gctgctgaca cttggataag tacccgtatg cagatagaga
     8221 cgggcaacgc ccttcgccac cgcctcttct cgcgcttact gcaaagccgc tggaacgaat
     8281 tggagcgttt ccataccgga gacgtagtga accgggtaga acaagacacc accgccatcg
     8341 tcacattgct cacctcttct gtcccggcat tcatcgtcac gagtatacaa ctgctggcag
     8401 cctttctatt cttctacttt ttagaccctt cactgccatg gctgattgtt gccatcctgc
     8461 ccgtctttct atcaggcagc cgtttctata tgcgacgaat gaaacgctat acacatgata
     8521 ttcggaacag tgacggtcgc atccagtccg tcatacaaga gagcctgcaa catcgcatag
     8581 tgattaaaac attggaacaa ggcgaacggc atctggacaa actcgatgac ttgcaagaca
     8641 tgctccacag ccaagtcatg ggacgtaccc gtttctcgct ttctgcccac atgttagtgg
     8701 cccttgcctt ttccggcgga tacctcacgg cttttctttg gggagccgtt cacctcagcg
     8761 caggctgtat caccttcgga acgatgaccg cctttttgca attggtagga aaagtccagc
     8821 gtcccgtgtt cgacctctca cgcctgatac cttccgtagt caatgccctt accgccatag
     8881 accggctatt ggaattggaa agactgccgg cagaagcgga tggtgacagc atattcctcg
     8941 cctctacccc ggaactggaa ctgaaagacg tgacttttcg ctacactccc gatgaccgtc
     9001 cggtattcag ccgcttctcc tgccgtttcc ccgccggtag ctgcatagct atagtcggag
     9061 aaacaggaaa aggaaagaca acgctcatcc ggctattgtt ggcactggca acgccacaag
     9121 agggacagat actcttgata cccgccaaac atccacttga aaccaatcat accgtctctc
     9181 cgcaaacccg caagaacttc gtatatgtcc cgcaaggcaa tacccttttc agcggaacta
     9241 tccgtgacaa cctgctgatg ggaaacccac aagcttctca agaagccata tatcaagccc
     9301 tgcaaaccgc caccgccgac ttcgtcttcc accttcccga cggcgtagac tccccactca
     9361 gcgaacgagg tggtggactc agtgaaggac aagcccaacg catcgccatt gcccgcgctc
     9421 tgctacgccc cggaaacatt cttcttttag atgaagccac ttctgccctc gaccccgaca
     9481 cggaacggct gttnnnnnnn nnnaaaacct gcgcagagac tgcgcaggca aaacatgtat
     9541 cttcgtcacc caccatccgg cagtagcgga ggcatgcgaa tctattgtcc gattataatc
     9601 agagaataag ccccaacggg tatctgcctt tggttaacaa actcagaaca gcttcgcagg
     9661 atactcgccc gcatccacca aagcctgaat cttgtcgact acactctgac ggtcttcggg
     9721 ataagtcaca ccgaaccact tgctggttgt atcaagcact tcgcaggtag cagtgccatc
     9781 gttaatcaac ttatctacca tcagcgggat gaagaattcg cttttcaggt tctccatatt
     9841 cttcgggtcg ctcaagaaac tcttgaaaaa ctctgcactg taagcaaaat aatcgggagt
     9901 gaaaccccag aagttcatgc tgaccggagt cgtctcggga gtggcagtcc attcaccgtt
     9961 atcgtcgatg tacttcacct cgccatccat acgctgaatc ttggtgcgtt ccactacgga
    10021 agtcagcagg ttgttcgcat ccgttccaca caatccacgg gatacggtac cgctctcgct
    10081 caacgtattg ccgatgcgga agcctaccat ggaatatacg tttttggagc cttcgggaag
    10141 ggctgcaagg aatttgccca ttacctggaa ggagtcacga ccgtagaaat cgtcgcaatt
    10201 gataacagca aacggttcct ttattacatc ggcacccatc attacagcat ggttggttcc
    10261 ccaaggtttg gtacggcctt cggggcaggt gaagccttca ggaaggtcat ctatggactg
    10321 gaataccagt tcgcagggaa tatggccttc gtatttggaa ataatcttgt cgcggaagtc
    10381 ctgttcaaaa tctttacgga ttacgaaaac gagcttgcca aaaccggcat tgatggcatc
    10441 gtaaatagaa taatccatga tagtttcgcc attcggtccc aatccgtcca attgtttcaa
    10501 gccaccataa cggctgccca taccggctgc caataagaat aaagttggtt tcatattagt
    10561 tattatttaa aaaggttagt gtatcatagt tgataacggt tgcaaatgta caaaaattta
    10621 tgtctgacaa aagggagttt tagttcattc tttaccacta tccgttcaaa aacgtacatt
    10681 tagaacggat aaccgatggc aaaatgcagt gccatactat ccttgaactt aggaatattg
    10741 taatatcccg actttccggt atcatacggg tcgtgaagcc cgatacccaa atccagacgg
    10801 aaaacaagga agtccaggtc atagcgtaag ccgaatcccg tacccaaagc aatctgtttc
    10861 gggaaattct tcaaggtgaa ctcaccgttc gggcgatttt cgtccttacg catcagccat
    10921 acattgccgg catccagaaa caccgctcca tgcaagtcgg caatcatacg gaagcgatac
    10981 tcgatattgg cttctatgcg aatatcaccc acgtggttga tataggtata tttcctatcc
    11041 gtctcgggag gatagccgcc cggacctata ctgcgtgcag aaaaggcgcg cacactgttg
    11101 gcaccgccga tatagaactg ttccgtataa ggtgcagtcg tagcgttgcc atacgaccat
    11161 atcacccctc cggcaatacg cgaggctatc atctgattct tgtctatccg gtaatggtac
    11221 ctgaattccg agttcagctt caggaactgt gcaaaaggta ccccgaaaag cttctttcct
    11281 tcctcactga acggcttgcc gaaaatacgg tagacggcag aagtcaggtt accggccgac
    11341 gcaacggtgg tctgccacca gatggggtta cgcttgccgc gcacggaagc gttgtcataa
    11401 gtataggtgt actccatggc aggaatgaac tggtcgcgca aactaacgta gagtgccgga
    11461 ttctcggcac gcaacgtatc gaaagcggca gtaggattgc gcagtacatt gaatgtcaac
    11521 cggaaaggag ttatactgtg cctggaagtc gatttgggct ggaagtcata agtgacatta
    11581 ccgccaaaag ccaacagctt ataatacttg gcacggttca tctggtcggc atataaacgg
    11641 aaagtcgttg tagccgggaa gtcatactca cggtcgccca tcctaggaaa caccacgcgc
    11701 ggaaagataa gcgaagtgga gatacccagt tcataactgt tcatcaagga agaacttgcc
    11761 ttgcccgtct gccattcgta cgaaccgttc aacttcacat tccagctttc accgccaccg
    11821 aagacattgt tcttcgtcac cgtaaaagcg gcacccggtc ccgtctggtt attgctcttc
    11881 atggtgacat taaaatccaa ctccgcatcg tagggtttat cgagcgcggc aatgaccctc
    11941 acatccaatg tatcagacac aaacgccgta tcacgcggta tatactgcat ctccgcataa
    12001 cggaaaatac cgacgcttgc cagacgctcc tgaatacggg tctgacggta caaactatac
    12061 aaactctgca tagaacgctg gcgggcaata cctgcgctgt cctgtatctg acgtttccgc
    12121 cgataacctt gatagttcaa ccaacggtaa agcatgttgg gacgtaccgg aggtttgttg
    12181 tagtaatgta tggtcaagcc tttgtaatcc atgctgtcat tgggttcctg cccctgcttt
    12241 ccaagaagat agacggattt acgccccaca cggaactgct tctcggctac ctttggcata
    12301 ccgggaacgg gaatcaagcg catctggaca tgcccattgg gaactatcat ggtatcggcc
    12361 tgataggtca ggtagtcggg acggaaataa taacagccca cattacgcag cagggtactg
    12421 atacgggtac gctccccatc caaatcagcc acattgaatt gttctcccga actgataagg
    12481 gaacgtcggc gtcccagctc cataatgcga gtggtacgct cgctgaaacc acgataatat
    12541 accgtatcta taaagtaggg gttacgcatg ttcaccgtat attgcaactt tgccttcagc
    12601 gagtccttcg ggtcgataaa tgtcttgtag ctgacgcttc cgttgaaata gccataatcg
    12661 cgcagcaagt taaccgccgc cttctggcgt atatcgggat tcaccgtaga cataagcacc
    12721 ggagtggcgg caaatttatt gaatatccac tttccgaatc ccttctcata cttctggaaa
    12781 ccattgtaaa tccacagtcc gaaaggaaag ggatagcgga tagtagagct tcccagcaac
    12841 gaattgttcg gtgccgtagc aagggcggct tccacctctt ccatagcaat ctcaccaaca
    12901 gacgtttcac tgcggttcaa tacaatcatc ggcttttggc cggtatagag tatctccccc
    12961 tcgggcaagt gcttcgtggt ggagcaacct gccagaaata tcaatcctgc aatatataat
    13021 atcagtcgtt tcatatcaca ttcctacttt ttcatatcgc tattttcagc ctccggtttt
    13081 atctttttct tcctgaagat gaagagttca ctcaatcggt ccatcttccg gcgcagcaca
    13141 aggccgacac ccgtttcggt tatctcaccg tcgagtatgc tttcgtagtt tttattatgg
    13201 aatacacgga catatcgagt acccgacgca tcaagacggt attccagcga tatattgtca
    13261 atgaatgatt ccgcatcgtt cgtggcattg gccccggtgg acacttttcc accgatgact
    13321 atctgtacgc ggtcgttgaa gaaacgctgg gaataacgaa aactgaagtc tttctgcgtg
    13381 tcacccgttt cagcagaggt acggtcttcc acacctacac tgatattggc gccttttata
    13441 cctcccgcca aggagtttat ctggctctga agcactgagt tcaaggcagc tcccattgac
    13501 aaacctcctc ctttggcacc actgttcaag taaatacccg tggcaagcat ggcaatggcc
    13561 tgcttgctac gctcttctgc acccattgcc tgcagctcat tctctactgc ggcatcttcg
    13621 ggcgccgaaa tatcgaatat caaatcggga gcgtcaagcc tgttcttgat ggaaatggaa
    13681 acatcgaagt tcaccatgcg cgaaccgtcc ccgtcaccat cggccacaga agcacgcata
    13741 cgttccgtag cctttaggct cagcgtagga ttcataatat tcccccgcca atccacataa
    13801 ctgccgggat tgaactggaa ctccttcaac gggatgatag gcagcgaata tttcatgacg
    13861 ccacccgaaa gggtatagcg tccggtaagg ctcatatccc cttggggagt atactgcata
    13921 ttcaaatcac cgccaccttc cagttcgatg tatttgctgc ggtcgggact caagtcagca
    13981 cgaagacgga cagcatcgtc aatatggacg gacatataca tttccaatcc tcccaaagac
    14041 atggtaggaa cctcatccgc ttttaccgac gtcgtatcgg tgaacgaggt aaaggtaacc
    14101 agcccgctga gacggtcttc caccgttaaa ggggaatcgg tcaacacgta ggttacgttg
    14161 gtattgccca gcaaattcat gtttccacgc atcgtgagcc cgtcaagcgg ccccttcacc
    14221 gtggcatgca agtcgacgaa cacctttcca tacaccagac tttcgcgagt acgcggtgca
    14281 tccagcaacg tatagttctc tgccagcaga ttgaggttgg cagtaggacg ctccatattc
    14341 cggaaatcaa ccttaccgtc aatcgtaaac ggattcttgc tggtggtata aatggcaaac
    14401 ttatcaaata tcaactgatt gtcctttatc tgtaccggac ggttgtcgaa ccagtaacgt
    14461 gctcccgcct ggcgtgcata gacagacaca ctgtccaaaa caatatcacc atgcatctga
    14521 ggcttgtcca gcgaaccata aatataaagc cctccatcaa tatctccggt aaaggccacc
    14581 gtttggtcag ggatgaatgc attggccatc ttcaatggaa aatgctcgaa acgggtggac
    14641 acttccaggg tatcctttcc gttcttctgc gtcaagatac cgtcggcggt catcacttct
    14701 tcattatcat atgtaaaata ggtattcaga tagtgcgtat tcttgtcgcc cggcaaccag
    14761 gtagccccca ggccgatgtc tccaaccggt tggcgttcgt aggtcagttt ctctacattg
    14821 gcttcggcgg acacctgcag ggaagtggca gtctgtatat aatttgcttc ggcggagaac
    14881 aatcccgtaa gccggggcat ataaggaagt acctccgtaa gttcatccag gcgcaatcgg
    14941 ctcagttcta cgtttatatt ctgcaaggaa agggtatcat tcttgtcgga ttgcatacgg
    15001 aaacacagac catcgtcgct gtccatatca atattggcat agacgcgcat attcttatgc
    15061 agataaatcc agttactatt gtccgcaaag tggaatttac ggaaagcgat aatcggctcg
    15121 gcaggaataa ggttcagcag cacaccatta ccgcgaccgt gtccttcggt caacggacgg
    15181 gcattaatac cgaatagaac accggtctgc ccttttccat tcacataatc cacagtcagt
    15241 tccgcatctt cattacggac ttcacccgtc agtgtgctac ggaacacaaa ctgcgggttc
    15301 ttgggaccgt ttatgacacc accttgcaac ttcatgcggg cagtatcctg cttcactgta
    15361 aaaaatatcg tatcgagctg caaggagtcc atgcgcaatc cgtgaacagc tgtacgtcca
    15421 ttgatgccga cttgcggagt aaatccgaag ctcagtttga aatcattata ggaaataccc
    15481 tttgcagcca ggaaatagct gacgggattc tggttaccgg cttccagatg catgcccgct
    15541 gaaggaagga cttggcgcaa agcggcatgg tccaaacgcc gttcatcaat ctgctttgtc
    15601 aggatagaga caaatttatc cgactgttcc atcaacctct tcaacgtgct gtgagcgcgg
    15661 aaacgcagat tcaagtcacc ggcatcaagc ctcaacttga gagaatcatg acgtgcctcc
    15721 gctcccattg taaaggcaaa cgggtgtttc aacggtcggg gcaccaaacc cagcttatgc
    15781 agattcacct cttccacatt taaatccaaa gcgccatcca gatagctgcg gtcaagacgc
    15841 atatccgcat ttccctgcat cttgagaagg acattatcgc tggcaagacg gacggtagca
    15901 acggatgact tgagtccggc atgcacatct acaccggaaa tgtcccaatg gccatactgt
    15961 agtttttcca aggaggcatt caaagcggcc acagtttttc gtgatgccac atccacccct
    16021 tgccccttag cggacatctt tgccgtaaga gtatagatag agtccttggg caggaagtga
    16081 tgcacctgca agttgttgat ggcaaggtcg gcatggtagg cttccgtagc aagattatag
    16141 gcggcgtcca aattcaaggc gccttccttc tccttcagtt tcagggcggc agtgcactgc
    16201 gccccctcca taccgagacg tgccgcaagg tgcatactgt ccggcacaat gatggagcca
    16261 tcgggagcaa tgtcagctag tccggtcagg aagttcaagt tctgcgtatg catttcgaag
    16321 tccatgcttc cattgcgttt cacactgtcg gtcaagctcc agaattctcc tcccccactc
    16381 aacgaaaagg ctccgggcag ctcagccgta aaacgggaaa tctgcatctg cttcaggttt
    16441 ccttccgtac cggcatgaat caccaacgga cggaatggat aggcttcctt gaaagcttcc
    16501 ggcaagccac cggcaaaaag cagtacatcc tgtttgccga tacgggcatt gaaacgggct
    16561 gtcagacggc cggtggtagg tatatttatc agttcccagt aagtctgtgc cgtaaggttc
    16621 atctcactat gaggtgtcag caacttcaaa gaagggatac ggataacggt agaatcggca
    16681 aacaaccgtc cggtcaggga ggtgacgctc aaaccggaac gctcatac
//
