LOCUS       c00082_gnlPro..        10789 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BJBEHNOB_82.
ACCESSION   c00082_gnlPro..
VERSION     c00082_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 10:53:43
            Original ID  :: gnl|Prokka|BJBEHNOB_82
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10789
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10789
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[494:6462]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      495..6462
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10789
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10789
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             495..2330
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg82_1"
                     /sec_met_domain="ILVD_EDD (E-value: 2.6e-217, bitscore:
                     711.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEIGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKK
                     AFTPPTRQREVSKALRAYGKMVSSADKGGVRIVED"
     CDS             2364..4067
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg82_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6e-51, bitscore:
                     161.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYKKVDYVRSYQPEPDIKKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELRAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             4083..4637
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg82_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.3e-17, bitscore:
                     52.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNEACVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             4644..5369
                     /locus_tag="ctg82_4"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             5419..6462
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg82_5"
                     /sec_met_domain="IlvN (E-value: 1.5e-47, bitscore: 150.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.9e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYDKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(6532..6873)
                     /locus_tag="ctg82_6"
                     /transl_table=11
                     /translation="MEARPTQKQVITSSLFWESYDNVYVQGLDLFGFYQAELYANKIKS
                     ILYELDQTYPYYPECRHLATKSRMYRNIILDSHLIIYRITEERIEVLDIVHSASSMRKI
                     KKTRNIHIE"
     CDS             complement(6840..7076)
                     /locus_tag="ctg82_7"
                     /transl_table=11
                     /translation="MTKLSNIPAKETTAKTAKTRKTKTGPAKLKWDPTKPVQFTQEEIW
                     EHIHEIEKGPFLTLDEGFKRFEAWKQDLLKSRL"
     CDS             7443..7643
                     /locus_tag="ctg82_8"
                     /transl_table=11
                     /translation="MRLVNRNNCVASKQASKQASKQASKQANPDLLYVYAGPVCGGFPP
                     HTGPACLRLAHGEKVILRMTR"
     CDS             7712..10789
                     /locus_tag="ctg82_9"
                     /transl_table=11
                     /translation="MKTILRGISMRLSLIAMVLCLCAAWPGHGLAWGMTGSASPAGMTP
                     GAPQSQAKGEVRFSNTLDPVAYSFIYKWDPMATWSLNFNIENFTKGMAVRVQLANTANP
                     DGVEFRFEDSEPAQTLDNGGFWIPDEKLTDYGYSVGLRLQMNSSKECSADYTVKVYSSR
                     DMGTAALASTGQTIRFMLGDKAPAMGELSRTSGDLNEDIPFAINVTKAGFLQGQHAKMK
                     IYLNGPSEGLTLSGQNLSKETGLYNEPIYVLDIPSFSATQFTLMAHATEEWNGTVQVDI
                     CDADDNRIVYGGQAPFVFPANNSQDDIAALKAIAEANPLNSDLQNFISNKDYLKDRGSN
                     DGYNVGVTWNTESTSRVKSFFIDDGRTQTVTTMDVSALSGLEQLDLQNTRLKSLDLSTL
                     TKLRSLSLYGNDSLTWFTVKLPNSLPENFWMNGYTTIMAGTPVDGNNAYAAAGTEIDLS
                     AYATVGGVKSVYQWYLIDRATGKRTKATMQAVSGKDGAFIFEGKPGEYYKCEITNNNYR
                     DWCMETPRIKVARGSADYSPADIAGLKKLAADNPNITQLKEFVDSKGWERENWNSYQDN
                     IRTDWSTGEVGRLTHLYIWFEWNSTDTISQLDLSAFTELRHFECENHMNISKLDVSKNT
                     KLEHLHIYSKNLSSIDLSKCPELRYFRFGTNRTLEGRYQDTKLAALNLTGCSKLTELYL
                     EHSPLASLDISSFKLLSRLEIEYCPNLKLQGFDKVTSLTYLALPHTEQFADLVKNLPAS
                     IRQLYLQDTEYELPSSQVGKNLESLGLPGYVESLDLAQYPNLSNLNADGSLLRYSTVKN
                     YRQINYEGWGRITLTSPSHPGDPYWFENGDTIDLSSEAVIDGIETVFLWVNAKYRTEEK
                     EALKPVPNRPGVFVLNSKEEKYGDYYCKLMNPRFCEITEINVRSGWQIETSRIHVETTV
                     PQVFAESDVATLARIVDASNNKALSEWWSSDAWKTNEGSLYAQAVWNDENPRRLIHLYM
                     YEMGESFTKKVDLAALDKLEILSLTGNRVEELTLPKN"
ORIGIN
        1 tttcttatga gatacgtgtt ctcgtaagtc gtgttatctg ataaaaatgt tatctggaat
       61 ctgttttaga taacatttgt ctttttactg tttctgtttg gaaatcgaag ttttttccct
      121 tctatacctt ccgattccta agtaatacac tcttgctcct gttaaaatgc aatcctaaaa
      181 tggtatttgc ttgagaattg aaagaaaaat gaagaatttt cttttaaatc ctttgcgcat
      241 atcaattatt gttctacatt tgcagcgtca aacaaacaaa gacaataaga aaagatgatg
      301 aacaacgtat tgcatattat tctcgtggtg gtccttctag tcattagtag gtaaggagaa
      361 aggtgtgtaa gaagttgtga agtcgtagag atatttctta agcctttctc catataggga
      421 aaggcttttt tattataaat aaatcaaggt agaggcgtgg ataaagcgct ctacgaacaa
      481 aaaataggaa agagatgaag aatccgttaa gaagctcatt tagcaccgaa ggtcgtagga
      541 tggccggagc ccgtgcgcta tggcgtgcca acgggatgaa agaggaacag ttcggcaagc
      601 ctattatcgc tatcgtaaat tcatttaccc agttcgtgcc ggggcatacg catttgcatg
      661 agatcgggca actggtcaag gccgagatcg agaaacaagg ttgtttcgcc gctgaattta
      721 atacgatcgc tatcgacgac ggtatcgcta tggggcacga tgggatgctt tactcgcttc
      781 cttcacgcga cattatcgcg gacagcgtgg aatatatggt aaatgcccat aaggcggacg
      841 ctatggtttg catcagcaat tgcgataaga tcacgccggg tatgcttatg gcttccatgc
      901 gattaaatat cccgacggtg ttcgtgtccg gtggcccgat ggaggcaggt gagctggatg
      961 gccgccatct ggatttgatc gacgcgatga ttgagtccgc cgatacatcg gtaagcgatg
     1021 agcgtatcga gcaggtggaa cgccatgcgt gtccgggttg cggttgttgt tccggtatgt
     1081 ttaccgctaa ctctatgaac tgcttgaacg aggcgatcgg tctggcgctt ccggggaacg
     1141 ggacgatcgt ggctacccat aagaaccgta tccaactttt ccgtgatgcg gctaagcaaa
     1201 tcgttgagaa cgcttacaaa tactatcgtg acggggatga ttccgtgtta cctcgcaaca
     1261 tcgctacccg tcaggctttc ttgaacgcca tgtcgctgga tatcgccatg ggggggtcta
     1321 ccaatacggt gcttcactta ttggccgtgg cacaagaagc cggcgccgat tttcatatgg
     1381 aggatatcga tatgttatcc cgcaagacac cttgcctgtg taaggtagcc ccgaatacgc
     1441 acacttatca tgtacaagac gtaaaccgtg ccggtggaat cctcggtatc atgaacgagt
     1501 tgatgaaagc cgggcttgtg gatggcagca cgagacgtgc ggacggcctg accttggccg
     1561 aggctgttga taaatacgcc gtcacttccc cgaacgtaac ggaggaggcg atccgtaaat
     1621 acaagagcgc tcccgctcat cggttcagta tccagatggg ttcccaagaa tcttattata
     1681 aggaattaga tacggatcgt gccgaaggtt gtatccgtga cgtggagcac gcttattcca
     1741 aggatggcgg cttggctgtt ttgagaggga atatcgcctt ggacggatgt gtcgtaaaaa
     1801 ccgccggcgt ggatgagagt atttggaaat tctccggccc ggcgaaagtc ttcgattcac
     1861 aggatgccgc ttgcgagggc attttaggag gcaaggtcgt ttcaggcgat gtggtcgtca
     1921 tcacgtatga gggtccgaaa ggagggccgg gaatgcaaga gatgttatat cctacctctt
     1981 atataaagag ccgtcactta ggtaaggagt gcgccttgat cacggatggt cgtttcagtg
     2041 gcggtacgtc cggtctttct atcgggcata tctctcctga ggccgcttcc ggtggcgcta
     2101 tcggactggt gagagacggg gatatcatcg agatcaatat cccggaacgt tccatcaacg
     2161 tgcggctgag cgacgaggag ttggccgagc gccgtaaagc ggaagaggcg cgtggaaaga
     2221 aagcctttac gccgccgacg cgtcagcgtg aggtctcgaa agcgttgaga gcgtacggga
     2281 agatggttag ctccgccgat aagggaggtg taaggattgt tgaagattaa agccaataat
     2341 atacattaaa cacgttattt cttatggaga aacaaaagat aaccggttcg gaagctttgc
     2401 tgaaagcgtt gattgctgaa ggagtagata ctatcttcgg ttatcccggc ggacaggcga
     2461 tacctattta cgacagttta tatgattata gggaccagtt gaggcatgta ttggtgcgcc
     2521 acgagcaagg cgctacccat gcggctcaag gatatgcccg tgtatccggc aaggtaggag
     2581 tgacgttggt tacttccggc ccgggcgcta cgaataccat cacgggtatc gctgatgcgc
     2641 tgatggatag tacgccaatg gtcgtaatcg ccggtcaagt accctcgccg ttgttgggaa
     2701 ccgatgcttt tcaggaagtc gacgtgattg gcatcacgca accgatcacg aaatgggctt
     2761 atcaaatccg caagccggag gagatcgcat gggctgtttc tcgtgctttt tatatcgctt
     2821 ctacaggccg tccgggtcca gttgtgctgg atttagcgaa ggacgcgcaa gtagggctgg
     2881 tggactatga atataagaag gtagattacg tacgtagtta tcagccggag ccggatatca
     2941 aaaaggatcg tatcaaggcc gccgccgatt taatcaatga ggcgaagaaa cccttctgtc
     3001 tggtcgggca gggagtattg ttaggcggtg cggaagagga attgagagcg tttctccaaa
     3061 agaatgatat acctgccgga tctacggtat tgggcttatc tgcgttgcca accgatttcc
     3121 cattgaacaa gggaatgctc ggtatgcatg gaaacgtagg gccgaaccgg aaaacgaatg
     3181 agtgtgatgt attgatcgct atcggtatgc gtttcgacga ccgtgtgact ggcgatttaa
     3241 agacatacgc taagcaagcc aagattatcc atctggatat cgacaactcg gaaatcggta
     3301 agaacgtccc cgtagatgta aaggtgctgg gtaatgccaa gcacacgata ccgatgatca
     3361 cggcgttgtt ggaagaacgt aaacgtccgg aatggaatgc cgagttcgat cgggacgaga
     3421 aagaggaata cgataaggta atcgagaagg aattgtatcc gaccgagggc caactgaaaa
     3481 tgggcgaggt agtccgtaag gtttccgagg cgaccggtaa cgacgctgta ttggtgaccg
     3541 acgttgggca gaaccagatg atgggtgtcc gctatttcaa atataaacaa acccgtagcg
     3601 tggtgacttc cggaggttta ggtacgatgg gatttggtct gccggccgct atgggcgcta
     3661 agttcggggc tccggaccgt acggtctgct tctttaccgg tgatgggggt atgcagatga
     3721 cgattcagga attgggtacc atcatgcagg agaaactgaa cgtgaagatt atcattctta
     3781 ataataactt cttaggtatg gtacgtcagt ggcaagaatt gttcttccac gagcgttatt
     3841 caaacaccat catggagaat ccggatttcg tggcgatcgc taaagcctat ggtatcgctg
     3901 gccgtgccgt tgaaaagcgg gaggaattgg acgacgctat cgccgagatg ctaaaccacg
     3961 acggcgctta cgtgttggtc gctaacgtgg agacttgcgg aatggtatat ccgatggttc
     4021 ctgccggggg aagcgtgaca aacatgatta tgggagacga gaaataagga ggagatgaag
     4081 ctatgacaac aaagaaatta tataccgtta ttatcttttc agagaatatc gtaggtcttt
     4141 tgaaccagat aacgattatc tttacacgcc gacagctgaa catcgagact ctgtccgtct
     4201 ctccgtccgc tatcaagggc atccataagt ttacgatcac gaccttcgcc gatgaggata
     4261 tgatcgataa ggtggtgaaa cagatcgata aacgtgtgga tatcttgaag gcttattata
     4321 atacggatga ggatctggtt tatcaagaga tcgcccttta taagctaagt accgagcttt
     4381 tcatcaagat gggaaccgtg gagggattga tccgtaaata caacgctcgt atcttggaga
     4441 tgaacgaggc ctgcgtggtg ttggagaaga gtggccacta tgacgagaca caagccttgt
     4501 tcaatgagtt gagcgagacg atcggtgtcc tgcaattcat ccgctccgga cgtgtggcta
     4561 tcacgaagag caaggtggag cgcttgagcg atatgttggc cgatatggag cgaaagttac
     4621 atgaaaagca acaataataa gatatggaga aagtaggatt atttcatttc gtggcggagc
     4681 cgtatttgat ggatttcagg ggacgtgtaa cgctccctat gattggtaac tatttgattc
     4741 acgccgcttc cagccatgcc ggagagcgtg ggttcggttt caatgatatg tcggagcgtc
     4801 atacggcttg ggtgttgtcc cgtctggcta tcgagatgaa ggaatatcct accgccttcg
     4861 ataagattaa tctatacact tggatcgatg aggtcggacg cctcttcacc agtcgttgtt
     4921 tcgagctggc ggatgagaat gggaaaacct ttggattcgc ccgttctatt tgggcggcta
     4981 tcgacgtgga gacccgccgt cctaccttat tggatataga ggcattgggc aaatatatcg
     5041 acgagcgtcc gtgcccgatc gagaagccgg gcaagatcat gccggcggag aataaggcgg
     5101 agggaatccc gtattcgatc aaatacagcg acttggatat caacggtcac ttcaatagcg
     5161 tgaagtatat cgagcacctg ctggatttgt tcgatatcga tcagttcaag acccgtgaga
     5221 tcggccgtct ggagatcgcc taccaatccg agggtaaaca aggtatgccg cttacgcttc
     5281 ataaggcgga gtccgctccc gataagcaag acatggctat ttgccatgag ggaaaggcga
     5341 tctgtcgtgc ggcggttact tggagataat aaaagagata cataaatagg tttttaaaca
     5401 ttaatagtta aaaagaaaat ggcacaaatg aattttggcg gtgttgtaga gaatgtaatg
     5461 acccgcgagg aatttccgtt ggaaaaggca agagagatat taaaagatga gacaatcgct
     5521 gttatcggct atggcgtaca gggaccggga cagtcattga accttcgtga caatggcttc
     5581 aacgtaatcg ttggccagcg ccaaggtaag acttacgata aagcggttga ggacggatgg
     5641 gttccgggtg agactctgtt cggtatcgag gaggcttgcg acaaggccac gatcatcatg
     5701 tgcttgttgt ccgacgctgc cgtaatgtct gtatggccta cgatgaagcc ttatttgaca
     5761 gctggcaagg ccctgtattt ctctcatggt tttgcgatca cttggaacga tcgtacgggc
     5821 gttgttcctc ccgcggatat tgacgtgatc atggtcgctc cgaaggggtc tggtacgtct
     5881 ttgcgttcca tgttccttga gggtcgtggc ttgaactctt ctttcgctat ctatcaagac
     5941 gctactggca aggcgatgga tcgtacgttg gcgttgggta tcggtatcgg ttccggctac
     6001 ttgttcgaga cgactttcat ccgtgaggct acttccgatt tgactggtga gcgtggttcc
     6061 ttgatgggcg ctatccaagg tttgttgttg gcccagtatg aggtattgcg cgagaatgga
     6121 catactcctt ccgaggcttt caacgagacg gtcgaggagt tgactcaatc cttgatgcct
     6181 ttattcgcca agaatggtat ggactggatg tacgcgaact gctctactac cgcccagcgt
     6241 ggcgctttgg actggatggg tccgttccac gacgcaatca agccggttgt cgagaaattg
     6301 tacgcaaacg taaaatgcgg taacgaggct cagatctcta tcgactcaaa ctctaagccg
     6361 gattatcgtg agaaattgga ggctgaattg aaggcattgc gcgagagcga gatgtggcag
     6421 acagctgtta ctgtacgtaa gcttcgtccg gagaacaact aatccaatct taatccttat
     6481 atatcagcaa aaagaggcgg gtcacttacg ggtggctcgc ctttctttgt gttattcgat
     6541 gtggatattc ctagtcttct tgatctttcg catgctggat gctgaatgga cgatgtccag
     6601 cacctcgatg cgttcctcgg tgatgcggta gatgataagg tgtgaatcta ggatgatgtt
     6661 ccggtacatg cggcttttcg tggctaggtg tcggcattcg ggataataag gataggtttg
     6721 gtctaactcg tataagatgg attttatctt gttagcgtat aattccgctt ggtagaatcc
     6781 aaataagtca aggccttgaa catatacatt atcgtaactt tcccaaaata aactactggt
     6841 tataacctgc ttttgagtag gtcttgcttc catgcctcaa aacgtttaaa accttcatct
     6901 agggttagga acggtccctt ctcaatctca tggatatgtt cccagatctc ttcttgggtg
     6961 aattgcaccg gcttggtggg atcccacttg agctttgcgg gtccggtctt ggtcttacgt
     7021 gtctttgcgg tcttggccgt agtttccttg gcggggatgt tgcttaattt tgtcatagtc
     7081 gtaatcgtta ttaattagta ctgtggcaaa tgtatggaat aatttccatg taataagata
     7141 tttggtaagg aaaaaagtag gtctatagga ttaactcatt acccagttgt agagacgggg
     7201 cgtgccccgt ctccatcccc tcaaaatggt attcaaattt atttatgtca cataaccgct
     7261 atttttaatc gcttatctgc tatatacgca caataagcat gaattttggg gtgtggggtg
     7321 tgcaggtctt tattacatat ttttttattt cttatattta ctacgtctta tacattaaaa
     7381 gagtatatga aaatcatatg atgatgtgtg atagatatat aatgttaacc ttttttatca
     7441 gtatgcgttt ggtgaatcgg aataattgtg tagcaagcaa gcaagcaagc aagcaagcaa
     7501 gcaagcaagc aagcaagcaa gctaacccag atctattata tgtatacgcc gggccggtat
     7561 gcggaggatt tcctccgcat accggcccgg cgtgtttgcg cttggcgcat ggagaaaagg
     7621 tcatcctacg aatgacacgc taaatcggga atggtgagag ataccgatac gtattatgaa
     7681 tacaaaacac ctatttataa atttattgct tatgaaaaca attttgcgag gaattagtat
     7741 gaggttgtcg ctcatcgcga tggtcttatg tttatgcgcc gcatggccgg ggcatgggct
     7801 ggcttggggt atgaccgggt cggcgagccc ggcgggaatg acacccgggg ctccacagag
     7861 ccaggcgaaa ggggaggtac ggttttccaa tactctggat cctgtagctt atagctttat
     7921 ctacaagtgg gatccgatgg ctacttggag cttgaatttc aatatcgaga acttcacgaa
     7981 gggcatggct gtacgtgtac agctggcgaa cacggcgaat ccggacgggg tagagttccg
     8041 ctttgaggat tctgagccgg cgcaaacgtt agacaatggc ggcttttgga taccggacga
     8101 gaagttgacg gactatggat atagcgttgg gcttcgtctg caaatgaata gctcgaagga
     8161 gtgttcggcg gactataccg taaaagtgta cagctcgcga gacatgggca cggctgccct
     8221 agcctctacc gggcaaacga tacgatttat gctcggtgat aaggctcccg ctatgggaga
     8281 gttgtcgcgt acatccggcg atctgaacga ggatatccct tttgcgatca acgtgacgaa
     8341 ggctggtttc ctgcaggggc aacacgctaa gatgaagatt tatctgaatg gcccttctga
     8401 aggcttgacc ctttccgggc agaacctaag taaagagact ggtctatata atgagcctat
     8461 atacgtatta gatattcctt cgttctccgc tacgcaattc acgttgatgg ctcacgccac
     8521 ggaggaatgg aacggaacgg ttcaagtgga tatttgtgat gcggacgaca ataggatagt
     8581 atatggcggc caagcaccgt tcgtttttcc ggccaataac tcacaggacg atatagccgc
     8641 tttgaaagcg atcgccgagg ccaatccgct gaactcggac ttgcagaact tcatctccaa
     8701 caaggattac ttgaaagaca ggggatcgaa cgatggctac aacgtgggcg tgacatggaa
     8761 caccgagtcc acgagccggg tgaaaagctt cttcatcgat gatggtagga cacagacggt
     8821 cactaccatg gatgtatcgg cgttgtccgg gttagagcag ttggacttgc agaatacccg
     8881 gttgaaatcc ttggatttgt ccactttgac aaaacttcgg agcttgagtt tgtatggtaa
     8941 tgattcgctt acttggttta cggtgaagct cccgaactcg ttaccggaga atttctggat
     9001 gaatggttat actacgatca tggccggtac tccggtagat ggcaataacg cttacgccgc
     9061 agcaggcacg gagatcgatc tatccgctta cgctacggtg ggtggcgtga aatcggtata
     9121 tcaatggtac cttattgatc gggctactgg taaacggacg aaagcgacta tgcaggcggt
     9181 atctggcaag gacggtgctt tcatatttga aggaaagccg ggcgaatatt ataagtgcga
     9241 gatcacaaac aataattaca gagattggtg tatggagaca ccaaggatca aggttgctcg
     9301 tggctctgca gactactccc ctgcggacat cgccggattg aagaagttgg ctgccgataa
     9361 cccgaatatc acccaattga aggagttcgt ggatagcaag ggctgggagc gcgagaattg
     9421 gaactcttat caagacaata tccgcacgga ctggagcacg ggtgaggtag gccggttgac
     9481 acatttatat atctggttcg agtggaactc tacggatacg atctctcaat tagacctaag
     9541 cgctttcacc gagttgaggc atttcgagtg cgagaatcac atgaatatct cgaaactgga
     9601 tgtatcgaag aacacgaagc tggagcactt gcatatatat agtaagaatc tgtcttctat
     9661 tgacctatcc aaatgtccgg aactgcgata ttttagattc ggtacgaatc gcacgttgga
     9721 gggacggtac caagatacga agctggcggc actgaacctt accggttgtt cgaagctgac
     9781 ggagctttac cttgagcatt cgcctttggc ttcgctggat atctcatcct tcaagctatt
     9841 gagccgtctg gagattgagt actgcccgaa cttgaagttg caaggtttcg acaaggttac
     9901 gagcttgacc tatttggcct tgccgcatac agaacagttc gcggatctgg taaagaacct
     9961 gccggcatct atccgtcagc tatatctgca agatacggag tatgagcttc cttcctcaca
    10021 agtagggaag aatttggagt cgttgggatt gccgggatac gtggagagtc tcgatctggc
    10081 tcagtacccg aacttgagta acttgaatgc ggatggatct cttttgagat attctacggt
    10141 gaagaactac cggcagataa attatgaggg ttggggacgc ataacgctta cttccccctc
    10201 tcatccggga gatccatact ggttcgagaa cggcgatacg atcgatctct cctcggaggc
    10261 cgtgatcgat ggcatagaga ccgtattcct atgggtaaac gccaaatata ggacagagga
    10321 gaaagaggca ttgaagccgg tgccaaaccg tccgggcgta tttgtgctga acagcaagga
    10381 ggaaaagtat ggagactact attgtaagct gatgaacccg aggttctgtg aaatcacgga
    10441 gatcaatgta cgttccggtt ggcagatcga gacctcacgt atccatgtgg agaccaccgt
    10501 cccccaagta ttcgccgaga gcgacgtggc taccttggca cgtatcgtag acgcttccaa
    10561 caacaaggca ttgagcgagt ggtggagcag cgacgcatgg aagacaaacg agggctcact
    10621 gtatgcgcaa gccgtttgga acgacgagaa cccgcgccgc ttgatacatt tatatatgta
    10681 tgagatgggc gaaagcttta cgaagaaggt agatctcgct gccttggata agctggagat
    10741 cttgtcgttg acaggcaata gggtggagga actgaccttg ccgaagaac
//
