LOCUS       gnlProkkaECIPKFHE_10   13370 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ECIPKFHE_10.
ACCESSION   gnlProkkaECIPKFHE_10
VERSION     gnlProkkaECIPKFHE_10
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 05:12:57
            Original ID  :: gnl|Prokka|ECIPKFHE_10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 22338
            Orig. end    :: 35708
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13370
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:10900]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10900
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..13370
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13370
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             complement(499..1131)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 144.4; E-value:
                     7.6e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_26"
                     /transl_table=11
                     /translation="MKLLCESVCFSYSGKQWIFENYNRVFTSGITILKGYSGCGKTTLL
                     KILAGYLSPQRGRVITPRRKVQADSLYRRKEVSYMFQGLNLLPLATVERNLQLCAEMAM
                     LPKKQWTRRADDLIARLGLESLRHKKAGSLSGGQAQRAALARTMMKDSDVLLLDEPTSG
                     LDDGNTEIIKNLIREYPADKICILSTHDSRLFDLTHEIIDFNLSVSL"
     CDS             complement(1128..2453)
                     /locus_tag="ctg10_27"
                     /transl_table=11
                     /translation="MVGRAKKCLWGIWLCSGLALCVWNAESAGGGADMAASKDACFIKT
                     FRAKIVPERLRSFVMPADGVVSNWIPADGRVQKDTIIATVNEDEIELERKELEVKILKD
                     RIAKEEELSKLEKQLEEIEFYSSLTREERQYASKQAEGGERAIRALKDKIELSKRELSL
                     VEDKPRLDFRKKEEKYILRMPFDGKLQYQFSIPPDNSVALYMDAASPIATVCDDSSYYL
                     TISISDPDLTNLPPESLSLSVPLGDGSALKGAFAFKRVEKNVSGGGELLAYFFRLPRQE
                     HARAHSMLGSNCTARLXXXXMTLFPEMVLDGLHTSIIGRAEEKGCISIEAVNIRDYTTD
                     KHKKVDDYTYGGGAGMLMQAQPVYDCWKAICEKIDKQKGKESTKRVVYVTPQGEVFHLN
                     KVRLASLPEGKKCSSWQELLEKVHPDLELVVNGETELIVRKK"
     CDS             2688..3125
                     /locus_tag="ctg10_28"
                     /transl_table=11
                     /translation="MSLFVTTIGPGAVHCPEVIVKFPLRIADEPVLRYTTEAMFIGALS
                     LLLAALMLTWGRSEPLPVNLTIIFHGPSPSSVEREAPKSSMVPEGRLSPSPLLPLPPQE
                     KSPRDKAAAEREDNTHLFVNRENIKKKIFFKDSDSVRRVNT"
     CDS             complement(3269..6775)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 136; E-value:
                     2.9e-41)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_29"
                     /transl_table=11
                     /translation="MGRESLYYCSGNAFPGMIQWFFDIPSKLIHWRLNLVRALGAYVPW
                     LRRDDGSMKVHAGTLVDLFATILSGRRHLSARDADAALDILRYTFPEVEHRWLSNRFER
                     SMRASLTVADVLASAASGRDETERMAIALEVLSLLINTGDSRMTGELFDQVTYGLELPG
                     TANHLRQLLMTPDVEAQEPAYSVGFSSGIGAEVSLPEQDKGISFRLIRCSRLVLVVNDG
                     TRPIVVRGRHLQPGGVMPLTNGQVVLLPSGPLSFEDFAFFLDCKRSGKQEVCYISLDGG
                     SLQISRVRSRASEVRVNMGLACEVEVLRPEVEFAVDGRRLYPGENVRMAYYSSFTLDGE
                     GPFSMGEVQNSMSDIGRRFRLDPGNRKLRVTNLPEKARKGDMLLTPGLAPGAVLEVSFS
                     SATNSGWLEVVEASMPLLLNGRPVRGRVSLRDGDVVHLNAYHALRCRFSAGVLDEEYHA
                     IRTLSVEGVTKEFLRSGRVLDNIDLTVKRGEMVCILGPSGSGKSTLLSMLAGQLPPTRG
                     CIRYNNQLLYSAPDLIRPYIAFIPREDILDAAMSVSEHISQATMIRRPRLSRSERVRRV
                     NAILKFLGLTHIASRRVGEMNARTISDGERTRLNLGLDLAGIADVFLLDEPISGLSTSD
                     AKLVMQTMQNMSRDKMVIATMHRPSTVILNQFHKVLVLDHGGQMAYWGDVPGMMRYFRK
                     AAADMAIDVSEEARTAGGADYVFEVLEAPLSWHDRRRRQHPRLWQERFEGYRFRNVMGH
                     HHEGGAPRTLYEGTLEFPPAPRRSVIQLWRLFRIWAVRTFLGRVRSRMGLYTMLLEGPV
                     LALLISVTLRASSSPEYTFATALHIPSYLFLATIVAMFFGLTGAASEVLKDRALLKRES
                     NAKVFVTGYVLAKALVLTGLSAVQSALFLWVGNSILEIHEMFLIYLGTMTLTAFVGVSL
                     SLLVSVFARTERAALNMVPLLLIPQILMAGAIVRFDEMNQFIPWSAHRTDEHGRLKPGR
                     VPLVAEFCPLRYSFETMVVDQASKNVWERERETIQEKVDDLKGRLHLDDREFEEFKLLK
                     MALLHIAAIGADGPEQAKAAVRQVRRAALGGSEKSYRRTIAELELLGVSRDALDRPEIF
                     LARRQPLPWGGSGLSPGDSGYSADDGTVPTPWKDSLFLFLMGAAPLLVTGRVLKRRLER
                     AG"
     CDS             6919..7341
                     /locus_tag="ctg10_30"
                     /transl_table=11
                     /translation="MDILVSTLCDFAADYQGKLCIQGGFDSLVARQFPVVHPVCAVALR
                     ICLTPEDEGTHELGLSIVDADGTPLDKERMPIKINFPVPAFPEGASFFTRNLIMNFQGL
                     RFEKPGNYSIDLTVDGELASRVPFRVVQVQEEAAQA"
     CDS             7679..8422
                     /NRPS_PKS="Domain: PKS_KR (1-140). E-value: 1.8e-09. Score:
                     29.6. Matches aSDomain: nrpspksdomains_ctg10_31_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     127.9; E-value: 7.7e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_31"
                     /transl_table=11
                     /translation="MVLIARNEAALRQLAAALEKRHSGLHASVLPCDLADEASLNMLIS
                     RLDSLPPGRTLLINNAGAGDYGDFSDGRWEKIRFLLRLNVESLTRLCHALVPSMKRNGG
                     DIINLSSLGALLPIPDFAVYAATKAYVSSLSEALRLELREHGIRVLAVCPGPVSTGFGK
                     AARRPGFTGNMMPGRNAFDTSVETVVKDSLRALARGRARVFPGMKIRLAAMLLAAAPLG
                     LIRLLMGRRPRKVLPASNDSPSSAS"
     aSDomain        7682..8098
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg10_31_PKS_KR.1"
                     /evalue="1.80E-09"
                     /label="ctg10_31_PKS_KR.1"
                     /locus_tag="ctg10_31"
                     /protein_end="140"
                     /protein_start="1"
                     /score="29.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VLIARNEAALRQLAAALEKRHSGLHASVLPCDLADEASLNMLISR
                     LDSLPPGRTLLINNAGAGDYGDFSDGRWEKIRFLLRLNVESLTRLCHALVPSMKRNGGD
                     IINLSSLGALLPIPDFAVYAATKAYVSSLSEALRL"
     CDS             8419..9999
                     /locus_tag="ctg10_32"
                     /transl_table=11
                     /translation="MKAHRRRIPRLTWFKLAVCICLVAMAASLFTPYPAQIIRALKGEP
                     EQAPPDSGTCPPQKSPPAEHPGQEEQPITAAPSASGKEPGDERLYTPWTPERTIALPPV
                     QYPPFPPVLPTRPAEGAMTHIYELARGLNLKTQVNFRPGTLASRDRETKSNYQMTLSLN
                     VKQPKALTKKEDILKLNPKLEPMLPGLSTLFRHARVSPYYGQIYVRKQTEIRKNLASLL
                     KLLDRHNYYDTETILETTYPDTGRKLLWLQSEMDVVSDGSDGDRLAAMPDKILKSSFYQ
                     PSTSYRWKKRTDKPNPLLKPWQQRLASYKKTLEKAPAAEKTALRRKIDHAERVIEELKR
                     YSFLISEYDPFIVVPLGVVNQSTPFSPQFGDYAVVIVGDKLYPALVGDAGPRYKTGEGS
                     LRLSREINPKAGPYSRPVSDLKVSYLIFPGSAEPEAGPPDYEKITDRCRELLNEIGGMG
                     KGFNLHQWEDLLAPKPPPAPKPESGGTAETPADKRKKEEAPGNKPAPAPAPPASPQTAP
                     ASSAAKSAA"
     CDS             complement(10001..10900)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_33"
                     /sec_met_domain="phytoene_synt (E-value: 6e-18, bitscore:
                     56.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGLDHLLSAVSRSFYLSMRFLPREMRPGVAVGYLLARATDTVAD
                     AVDMDCRERLALLRMMGETVAGSASREVAATCFGRLGVLSTIQTHRGEAELLARFPECL
                     ALLENLSPHERMLVRQVLASIVEGQAWDLMYFESHAAVSCPEQLEHYTYMVAGCVGEFW
                     TRLGLLAQGPGFSTQPEEQLLRWGRHYGMGLQLVNILRDREEDLARGRSYLPAPDDRPW
                     LDRAERWLKEGVFYAESLRNGRLRFSTVLPAWLGLDTLELLQRADRRHPSSGKVKIARG
                     DVYLRMWKAFLFSWKEAL"
     CDS             complement(10897..12396)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 427.4; E-value:
                     1.2e-129)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg10_34"
                     /transl_table=11
                     /translation="MEMVVLKEISSAIVNERNGTALLRHILDVLYRRMKMLRGTFTIRR
                     GNDLMIEASHGLDEQEMKRGHYHVGEGITGHVAETGRPHVIEDISRDSRFLNRTRTRKS
                     GEKVAFICVPIIHLQQVIGTLSIDRAVDRDTDLERDQKLLEIVGNIVGDALAASLQAHE
                     ERAALVAENEKLRELLTTNPGELIGNCSTMLQVYEQIRQVAPSDATVLIRGSSGTGKEL
                     VARAVVNLSGRKDKPLVTLNCAAMPENLLESELFGHEKGSFTGATSRRIGRAEAADGGT
                     LFLDEIGDLSLQMQVKLLRFLQEKTFSRVGSNRELHADVRFIAATSRNLEELMAANKFR
                     EDLYYRLNIFPIVMPDLSKRKGDVMLLAEHFLSKFNLKYGKDIKRLSTPAINMLMAYHW
                     PGNVRELENCMERAVITAQDDCIYGYNLPASLQMPSHDVPYSRDGEAPADLPTMVDSFE
                     RELIVAALKRSPGNMSAAARELGISPRVLHYKMHRLGLQKS"
     CDS             complement(12622..13368)
                     /locus_tag="ctg10_35"
                     /transl_table=11
                     /translation="MAMTPTLYVGSMVGFIFSTVLTSLGMEGNHTVAYAMVGMASFFAV
                     AAQAPLTALVMVVEFSMSGQMIYPLLIGVVSAYGTGKLIRARSMYAASLAGSPASVVNL
                     PMAQVHVHDLARHVVPQVAPDASLDDVSSLMLRNPGDLVFVVNKDGIYEGAIYPEDFLA
                     VRRQMEERKGAVPADAGSLVRTGAPVLDAGTYLTDALKLFEQTHLPAFPVVWKNTGRLD
                     GVLYRNALFQVITEMMKRESGGDVGM"
ORIGIN
        1 ggatacagcc tgcccagcaa atgcccctcc ggcagagggg aggcattcag ggaaaaatca
       61 aaatccgcta tggtaaccgt acaaggcccc gcctgcaacg ggctccggga gggattgtac
      121 agaaggacgg tagccacgtc ctccaaccca agcgcggaaa gaaaggaaca ggactccatg
      181 ttgtattcca ggatggggaa tactgtcttg cccacgcgcg ccacgcccgc acgggcatca
      241 ttcagcacca ggacatcgca gccatacagg gaaggcagtt catgctgcag caaatttttc
      301 ttggaaggct ccccgtcgcg cacggtatca aaaacaataa tcagatccgc cccgttcttc
      361 ctgatttcat catgcagcat tttggcggag aggacataat tggcgagaaa agagagagcg
      421 cacagggaaa ggaagaaggc caccagaatc cgtgaaaggg ggctggccgg gcgttccttc
      481 caacggtgga gagtatcttt aaagagatac agacaggtta aaatcaatga tttcatgggt
      541 caggtcaaac agccgggaat catgcgtgct caaaatgcaa attttgtcag cagggtactc
      601 cctgatcaaa tttttaatga tttccgtatt gccgtcatcc aggccggaag taggttcatc
      661 cagcagcagc acatcggaat ccttcatcat cgtgcgggca agagccgccc gctgggcctg
      721 gccgccggac aagctccccg cctttttatg cctcagagat tccaggccca ggcgggcaat
      781 caaatcatcc gccctccgcg tccactgctt ttttggcagc atggccattt ccgcgcataa
      841 ttgaaggttt ctctccaccg tagccagggg aaggagattg agcccctgga acatgtaact
      901 cacctccttg cgccggtaga gggaatccgc ctgaaccttc cggcgggggg taatcacgcg
      961 cccgcgctgc gggctcagat accccgccag aatctttaac agcgtcgttt tcccgcatcc
     1021 ggaatacccc ttcaaaatgg tgattccgga agtgaacacc ctgttgtaat tttcaaaaat
     1081 ccactgcttg cctgaataac tgaaacagac tgattcgcac agcaatttca tttttttcga
     1141 acaatcaatt ccgtttcccc attcaccacc agctccaggt ccggatgcac tttttcaaga
     1201 agttcctgcc aggacgaaca tttttttcct tccggcaggg aagccagcct caccttgttg
     1261 agatgaaaca cttctccctg cggtgttaca tagaccacgc gctttgttga ctctttccct
     1321 ttttgtttgt caattttttc acagattgct ttccaacaat cataaacagg ctgtgcctgc
     1381 atcagcattc cggcgccgcc tccatacgta taatcgtcaa cctttttatg cttgtccgtc
     1441 gtataatcgc gtatatttac cgcttctatc gaaatgcatc ccttttcctc tgcacgcccg
     1501 ataatgctgg tgtgcagacc gtcaagcacc atctccggaa acagtgtcat annnnnnnnn
     1561 naaagacggg ccgtgcagtt ggaacccagc atggaatggg cgcgcgcatg ctcctgacgg
     1621 ggcagacgga aaaaatacgc cagcaattcc ccgccgccgg aaacattctt ctccacccgc
     1681 ttgaaggcaa aagccccctt cagggcggaa ccgtcgccca gagggacgga cagggaaagg
     1741 gattccggcg gcagattcgt caaatcaggg tccgaaatgg aaatggtcag ataataagag
     1801 gagtcatcgc acacggtcgc aatcggggac gcggcgtcca tgtacagggc tacgctgtta
     1861 tccggcggaa tggaaaactg gtactgcagc ttcccgtcaa aaggcattct gaggatatat
     1921 ttttcctcct tcttgcgaaa atccagacgc ggcttgtcct ccaccaggga caactccctt
     1981 ttggaaagct caatcttgtc tttcaaagcc cggatggccc tttccccgcc ttccgcctgc
     2041 ttgctggcat attgccgttc ctccctcgtc agggaagagt agaattctat ctcttcaagc
     2101 tgtttttcca gctttgacaa ctcttcctcc ttggcgatgc ggtccttcag gattttgacc
     2161 tccagctcct tgcgctccag ctcaatttca tcttcattga ccgttgcaat aatggtatcc
     2221 ttctgaacgc gcccgtccgc aggaatccag ttgctgacaa ctccatcggc cggcatgaca
     2281 aaggagcgca gcctttccgg gacgatcttg gcgcggaaag tcttgatgaa acaggcatct
     2341 ttcgatgccg ccatatcagc ccccccgccg gccgattccg cattccagac acaaagagcc
     2401 agccccgagc acagccagat gccccaaaga catttctttg cccttccgac cataatttca
     2461 aacaggcctg ccccccgttt cacggcagca aagccccgtc ataaatgatc agaactcagg
     2521 ataccgtgta actcaccgtt ccttccgtag cggtccagtc ctgcgcttca acctcgcctt
     2581 catcattctc aacgggaacc tggtaaatga tggaaccggt gaacgtcccg ccacagctct
     2641 cacgttcatt ggaagtgttg aaggaaatgt tcgcatccac aaaggccttg tccctgtttg
     2701 tcacgacaat cgggcccgga gccgtccact gtccggaagt aatcgtgaag ttccccctca
     2761 gaatagcgga tgagcccgtc ctgcggtaca ctacggaagc aatgttcata ggagcacttt
     2821 cattgctgct tgccgcatta atgcttacct ggggaaggtc cgaaccattg cccgtcaatt
     2881 tgacgataat attccacggc cctagcccat cttccgtgga aagagaagcg cccaagtcca
     2941 gcatggtgcc ggaaggaagg ctttccccgt caccgctgct gccgctgcct ccgcaggaaa
     3001 agagtccaag ggacaaggct gccgcggaaa gggaagataa tacgcacctg ttcgtcaatc
     3061 gggaaaacat aaagaaaaag attttcttca aggatagtga ttccgtccgg cgcgtcaaca
     3121 cataaataaa agaatatttg gaggggcctt ccgttgtttt gcggaatgca ccggggctta
     3181 cggcccgctg ccattccccg gacgcgcacg ccggattttc cgctttgcgg cggaaaatcc
     3241 agacgccaat ccccacaggc cgcaaacgtc atccggccct ttccagcctg cgcttgagga
     3301 cgcggcccgt gaccagcagg ggggcagccc ccatcaggaa caggaacagg gaatccttcc
     3361 atggggtggg aaccgttccg tcatccgcgc tgtatccgga atcccccggg gacaggccgg
     3421 agcctcccca gggcagaggc tggcggcggg ccaggaaaat ttccggcctg tccagggcat
     3481 cccggctgac gcccaggagt tccaattccg caatggtccg cctgtagctt ttttccgaac
     3541 cgccaagggc ggccctccgc acctgccgga cagcggcttt agcctgttcc gggccgtccg
     3601 ctccaatagc cgcaatgtgg agcagcgcca tcttgagcag cttgaattct tcaaattccc
     3661 tgtcgtccag atgaaggcgg cccttcaggt cgtccacttt ctcctggatg gtttcacgct
     3721 ccctctccca tacatttttg gacgcctggt ccaccaccat cgtttcaaag gagtagcgca
     3781 aggggcagaa ttccgccacc agcggcacgc gccccggctt gaggcgcccg tgttcatccg
     3841 tacggtgggc ggaccatggg atgaactggt tcatttcatc aaagcggaca atggctccgg
     3901 ccatcaatat ctggggaatc agaagcagag gcaccatgtt aagcgccgcc ctctccgttc
     3961 tggcgaatac ggaaaccagc agggacaggc tcacgccgac aaaggccgtc agggtcatcg
     4021 tccccaggta aatcaggaac atttcatgga tttccagaat ggagttcccc acccaaagaa
     4081 acagggcgga ctgcacggcg gaaagccccg tcagcaccag cgccttcgcc agcacataac
     4141 cggtcacgaa taccttggca ttgctctccc tcttgagcag ggcacggtcc ttgagcactt
     4201 cgctggccgc cccggtcagg ccgaagaaca tggccacaat ggtcgccagg aacaggtagg
     4261 aagggatgtg gagggccgtg gcaaacgtgt attccgggct ggaagaggcg cgcagggtca
     4321 cggaaatcag cagggccagc accggccctt ccagcagcat ggtgtacagc cccatacggc
     4381 tccgcacgcg ccccaggaag gtgcgcacgg cccagatgcg gaaaagccgc cagagctgta
     4441 tgacgctgcg cctgggggca gggggaaatt ccagcgtgcc ttcatacagc gttctggggg
     4501 cgcccccttc atgatgatgc cccatcacgt tgcggaaccg gtagccttca aagcgctcct
     4561 gccacaggcg ggggtgctgc cgcctgcggc ggtcgtgcca ggagaggggg gcttccagca
     4621 cctcaaacac gtagtccgcg cctccggccg tccgcgcctc ctcggatacg tcaatagcca
     4681 tgtccgctgc cgccttccgg aaataccgca tcatgcccgg cacgtccccc cagtaagcca
     4741 tctggccgcc gtggtccagc accagcactt tgtggaactg gttcagaata accgtgctgg
     4801 gccggtgcat ggtggcgatt accattttgt cgcggctcat gttctgcatg gtctgcatga
     4861 ccagcttggc atctgacgtg gacaggccgc tgataggttc gtccagcagg aaaacatccg
     4921 caatgcccgc caggtcaagc cccaggttca ggcgcgtgcg ctccccgtcg gaaatggtgc
     4981 gggcgttcat ctcacccacg cggcgggagg cgatgtgcgt caggcccaga aatttcaaaa
     5041 tagcgttcac gcgcctgacg cgttccgacc ggctcagccg cggacggcgt atcatggtgg
     5101 cctgagagat gtgctcggaa acgctcatgg ccgcatccag aatatcttcc cggggaatga
     5161 aggcgatgta gggccggata agatccgggg cgctgtacag aagctggttg ttgtaacgga
     5221 tgcagccccg ggtgggcggc agctggccgg ccagcatgga gagcagcgtg cttttcccgg
     5281 atccgctggg ccccaggatg cacaccattt ccccgcgttt cacggtcagg tcaatattgt
     5341 ccagcacgcg cccggagcgc aggaattcct tggtcactcc ttccacgctg agggttctga
     5401 tcgcatggta ttcttcatcc agcaccccgg cggaaaaacg gcagcgcaga gcgtggtagg
     5461 cattcaggtg caccacgtcc ccatccctca gggaaaccct tccccgaaca ggccggccat
     5521 tgagcagcag gggcatggag gcctccacca cttccagcca gccggaattg gtggcgctgg
     5581 aaaaagaaac ctccagcacc gctccggggg ccagcccggg agtcagcagc atgtctccct
     5641 tacgcgcctt ttccggcagg ttggtcaccc gcagcttgcg gtttccggga tccaggcgga
     5701 aacggcgccc gatgtccgac atggaattct gcacctcacc catggaaaaa ggcccttccc
     5761 cgtccagcgt gaaggaggag taataggcca tgcgcacgtt ttcaccgggg tacagccgtc
     5821 tcccgtcaac cgcgaattcc acttccggcc tcagcacctc cacctcgcac gccagcccca
     5881 tgttcacgcg cacctcgctg gcgcgggaac gcacccggct gatttgcagg gagccgccgt
     5941 ccagggaaat atagcatact tcctgcttgc ctgaacgctt gcagtccaga aaaaacgcga
     6001 agtcttcaaa actcagcgga ccggacggca gcagcaccac ctgcccgttg gtcagcggca
     6061 tcaccccgcc gggctgcaaa tggcgcccgc gcaccacaat gggacgggtg ccgtcattca
     6121 ccaccagcac caggcgggaa caccggatca ggcgaaagga aatgcccttg tcctgctccg
     6181 gaagggatac ctctgcaccg atgccggagg aaaaaccgac gctgtacgcc ggttcctggg
     6241 cttccacgtc cggcgtcatc agcagctgcc tcaggtggtt tgccgtgccc ggcagttcca
     6301 gaccgtacgt cacctggtca aacagctccc ctgtcatgcg ggaatctccc gtattgatca
     6361 gcagggaaag cacttccaga gctatcgcca tgcgttccgt ctcatccctg ccggaagctg
     6421 cggaggccag gacatccgca accgtcaggc tggccctcat ggaccgttca aaacggttgg
     6481 aaagccagcg gtgctccact tccgggaaag tatagcgcag aatatccaga gcggcgtccg
     6541 catcacgggc gctcaaatgg cggcgtccgc ttaaaatagt ggcgaacaag tccaccagcg
     6601 ttccggcatg caccttcatg gagccgtcgt cacggcgcag ccacggcacg taggcgccca
     6661 gcgccctgac cagattcagc ctccagtgaa tcagcttgga aggaatgtca aaaaaccatt
     6721 ggatcatgcc cggaaacgcg ttgccggaac agtagtacag ggattcccgc cccatctcaa
     6781 gcgcaaccgg aatttcacgg agaaatgaca atattttcta cagctttatc ttgcaatagg
     6841 tccggaggaa gtatagttct gtccaatgtt catgctttcc gcgtgaaagc tagccaaata
     6901 catcaacatt atcacaacat ggatatttta gtttctactc tttgtgactt cgccgccgac
     6961 taccagggca agctctgcat ccagggcggc tttgactccc tggtcgcccg ccagttcccg
     7021 gtcgtgcatc ccgtctgcgc cgttgccctg cgcatctgcc tcactcctga agacgaaggc
     7081 acgcacgaac tgggcctgag catcgttgat gccgacggca cgccgctgga caaggaacgc
     7141 atgcccatca agatcaattt cccggttccc gctttcccgg aaggagcctc tttcttcacc
     7201 cgcaacctga tcatgaactt ccagggcctg cgttttgaaa aaccgggcaa ctactccatc
     7261 gacctgacag ttgacggcga actcgcctcc cgcgtgccct tccgcgtagt gcaggtgcag
     7321 gaagaagccg cccaggccta agaaaccatc ccctcttcca tcaaaccgcc tcccgttcat
     7381 ccggcaggcg gttttttatt ggagcggccg tccgcccgga agtgcggaac agggcggccc
     7441 cggttccatg cacctgaaaa cctctgcgcc tggccccggc ctaaaaaagg gaggccggct
     7501 ttttgcgtcc tccttccccc tttttcattg cggttccgca ccggattgac catgatacgg
     7561 gctgctccaa cccgccatgc acaccgcacg cctccaatac gacaggatta tcattacggg
     7621 cgcatcatcc ggcttcgggg aagcgtttgc cggaacgctg gccccccata cggcggaatt
     7681 ggtgctcatc gcccggaatg aagccgccct gcgccagctt gccgccgccc tggaaaaacg
     7741 ccattcaggc cttcacgcct ccgtccttcc ctgcgacctg gcggacgaag cctccctgaa
     7801 tatgctcatt tcccgcctgg acagccttcc tccgggaaga acccttctga ttaacaacgc
     7861 cggcgccggt gattacggag atttctcgga cggccgctgg gaaaaaattc gttttctgct
     7921 gcgcctgaac gtggaaagcc tcacccgcct gtgccatgcg ctggtcccct ccatgaagag
     7981 gaacggaggt gatatcatca acctcagctc cctaggagcc ctcctgccca ttccggattt
     8041 tgccgtttat gcggccacca aggcttatgt ttccagcctg tcggaagcgc tgcggctgga
     8101 actgcgcgaa cacggcatac gcgtgctggc cgtctgcccg ggcccggttt ccacgggttt
     8161 cggaaaagcg gcgcgccgcc ccggcttcac cggaaacatg atgccggggc gcaacgcttt
     8221 tgacacgtcc gttgaaaccg tcgtgaaaga cagcctccgt gccctggccc gcggacgcgc
     8281 ccgggtcttc cccggcatga aaatacgact ggccgccatg ctgctggccg ccgcccctct
     8341 ggggttgata cgccttttga tgggcaggcg cccccggaaa gtcctgccgg catccaatga
     8401 ttctccttct tcagcatcat gaaagcgcac cgccgcagaa taccccgcct cacctggttc
     8461 aagctcgcag tctgcatctg cctggtagcc atggcagcct ccctgttcac gccgtacccc
     8521 gcccagatca tacgcgccct gaaaggggag ccggaacagg cgccgccgga ttccggaacc
     8581 tgtccgcccc agaaatcccc ccccgcggaa caccccgggc aggaagaaca gccaataacc
     8641 gctgcaccat ccgcctccgg aaaggaaccc ggggatgaac ggctgtacac tccatggacg
     8701 ccggagcgca caatcgccct ccccccggtg cagtaccccc catttccccc cgtgcttccc
     8761 acaaggcctg cggaaggggc catgacccat atttatgaac tggcccgcgg cctgaacctg
     8821 aaaacgcagg ttaatttccg gcccggcacc ctggcctcca gggacaggga aaccaaaagc
     8881 aattaccaga tgaccctttc cctgaacgtc aaacagccca aagcattgac gaaaaaggaa
     8941 gatattctga agctcaatcc gaaactggaa cccatgcttc ccggcctgtc caccctgttc
     9001 aggcatgcgc gcgtctcccc ttactacggg cagatttacg tccgcaaaca gacggaaatc
     9061 cgtaaaaacc tggcctccct gctcaaactt ctggatcgcc ataattatta cgatacggag
     9121 acgattctgg aaaccaccta tccggacacg ggaaggaagc ttctctggct gcaaagtgaa
     9181 atggatgttg tttccgacgg ctcggacggg gaccggctgg ccgccatgcc ggataaaatc
     9241 ctgaaaagct ccttctatca gcccagcact tcctaccgct ggaaaaagcg cacagacaag
     9301 cccaatcccc tgctcaaacc ctggcagcag aggctggctt cctacaagaa gacgctggaa
     9361 aaagcccccg ccgcggaaaa aacggctctg cgccgcaaaa tagaccatgc ggaacgggtc
     9421 attgaggaac tgaagcggta cagtttcctg atctcggaat acgatccgtt catcgtggtt
     9481 ccgctgggag tcgtcaacca gtccactccc ttctccccgc agttcgggga ctatgccgtc
     9541 gtcatcgtgg gagacaagtt gtacccggcc ctggtgggag acgccgggcc gcgctacaaa
     9601 accggggagg gttccctgcg cctgagccgt gaaatcaacc ccaaggcggg cccttacagc
     9661 cgccccgtct ccgacctgaa ggtaagttac ctgattttcc ccggttccgc agagcccgag
     9721 gccgggcctc ccgactatga aaaaattacg gacagatgcc gggaacttct caacgaaata
     9781 ggcggcatgg ggaaaggatt caacctccac cagtgggaag acctgctggc gcccaagcca
     9841 ccgcccgccc caaaaccgga aagcggcggc acagcggaaa cacctgcaga taagcggaaa
     9901 aaggaggaag cccccggaaa caagcctgct cctgctccgg ctccgccggc ttccccgcaa
     9961 actgctccgg cttcatcagc cgcaaaaagc gccgcataag ctacagagcc tctttccagg
    10021 aaaaaagaaa ggctttccac atccgtaaat aaacgtctcc gcgcgcaatc ttcaccttcc
    10081 cggaagacgg atgccgccga tccgcccgct ggagcagttc cagcgtgtcc agccccagcc
    10141 aagcgggcag gacggtggaa aaacgcagcc gcccgttccg cagagattcc gcgtaaaaca
    10201 cgccttcctt cagccagcgt tccgcgcggt ccagccatgg acggtcatct ggggcgggca
    10261 aatagcttct tccgcgggcg aggtcttcct cccggtcacg caggatattc actaactgca
    10321 gccccatgcc atagtgcctg ccccagcgca aaagctgctc ctccggctgc gtgctgaagc
    10381 ccggcccctg ggccagcaag cccagcctgg tccagaattc ccctacgcat ccggccacca
    10441 tgtaagtata atgttccagc tgttccgggc atgagacggc agcatggctt tcaaaataca
    10501 tcaaatccca cgcctgtccc tccacgatgg aggccagcac ctgccgcacc agcatccgtt
    10561 catgcgggga aaggttttcc agcagcgcca ggcattcggg gaaacgggcc agcaattccg
    10621 cctccccccg gtgcgtctgg attgtggaaa gaacgcccag acggccaaaa caggtggcgg
    10681 caacctcccg ggaggcagag ccggccaccg tctcccccat catcctcaaa agcgccaggc
    10741 gctcccggca atccatgtcc acggcatccg ccaccgtatc cgtggcacgc gccagcagat
    10801 agcccacggc cacgccgggg cgcatttccc ggggcaggaa gcgcatgctc agataaaagg
    10861 atcgggagac ggccgataaa agatggtcaa ggcctttcat gatttctgca ggcccagcct
    10921 gtgcatctta taatggagta cccgcgggga aatgcccagt tcccgggccg cggcggacat
    10981 attgcccgga gaacgtttca atgcggctac aatcaattcc cgttcaaagg aatctaccat
    11041 ggtcggcaaa tcggcgggag cctccccgtc acgggaataa gggacatcat ggctgggcat
    11101 ctggagggag gcgggaaggt tgtaaccgta aatgcagtcg tcctgcgccg taatgacggc
    11161 acgttccatg cagttttcca gctcccggac gttgccgggc cagtggtaag ccatgagcat
    11221 gttgatggcg ggggtggaca gccgtttgat atcctttccg tatttcaggt tgaacttgga
    11281 aagaaaatgt tccgccagca gcatgacgtc ccccttgcgt ttggagaggt ccggcataac
    11341 aatggggaaa atgttcagcc ggtagtacaa gtcttcccgg aacttgttcg ccgccatcag
    11401 ttcctccaga ttgcggctgg tggcggcgat gaagcgcacg tctgcatgaa gctccctgtt
    11461 gcttcccacg cgggaaaagg tcttttcctg aagaaagcgc agcagcttca cctgcatctg
    11521 gaggcttaaa tccccgattt catccagaaa cagggtgccg ccgtccgccg cctccgcccg
    11581 gccgatgcgg cggctggtgg ccccggtaaa agaacccttt tcatgaccaa acagctcgct
    11641 ttccagcagg ttctccggca tagccgcaca attcagcgtg accagcggct tatcctttct
    11701 gccgctcaga ttcaccacgg cgcgcgccac cagttccttc cccgtcccgg aacttccccg
    11761 tatcagcacc gtggcatcgc tgggcgccac ctggcggatc tgttcataca cctggagcat
    11821 agtgctgcaa ttgccgatca attcgcctgg attagtcgtc aaaagctccc gcagtttttc
    11881 attttccgcg accagggcgg cacgttcctc atgcgcctgg aggctggcag ccagagcatc
    11941 cccaacaata ttgcctacaa tctccaacag tttctgatcc cgttccaggt cggtgtcccg
    12001 gtccacggca cggtcaatgc tcaacgtgcc gatgacctgc tgcaaatgaa tgatgggaac
    12061 gcagatgaag gctacttttt caccgctttt gcgcgtgcgg gtacggttca ggaacctgga
    12121 atcccgggaa atatcctcaa tcacatgggg cctgcccgtt tccgccacat gccccgtaat
    12181 gccttccccc acatggtaat ggccgcgttt catttcctgc tcgtccaggc cgtgggaggc
    12241 ttcaatcatc aaatcgttcc cgcggcggat ggtgaacgtg ccgcgcagca ttttcatgcg
    12301 gcggtaaagc acgtccagaa tatgccggag caaagccgtg ccgttgcgtt cattgacaat
    12361 ggcggagctg atttctttca gcacgaccat ctccaaatcc ggtgacctgt ttatttcatt
    12421 catgcaatcc ggggctgggc gaatattaac cgcacgcccc cgccatacca actacttttt
    12481 cttccaccgc catgcagccg ggcaaaaaaa acggcacggg gaatatggat aacataccag
    12541 caattaatgt tgatgatatt acgaacgggg aacaaaagat ttttacaaaa atgtaatata
    12601 catcccttgt ttcgttccgt tttacatgcc cacgtctccg ccggactccc gtttcatcat
    12661 ctccgtgata acctggaaca acgcgttgcg gtacagcacg ccgtccagcc gaccggtatt
    12721 cttccagacc acgggaaagg cgggaagatg ggtttgttca aacagcttca aggcatccgt
    12781 cagataggtg ccggcgtcca gcacgggagc ccccgtacga accagggacc cggcatcggc
    12841 cggaaccgcc cccttccgct cctccatctg ccggcgaacc gccagaaagt cctccggata
    12901 gatggcccct tcataaattc catccttatt caccacaaaa accagatccc cgggattccg
    12961 cagcatcagg gaggagacat catccaggga agcatccggg gccacctggg gcaccacgtg
    13021 ccgcgccagg tcatgcacat ggacttgcgc catgggcagg ttgacgacgg acgccggact
    13081 gccggccagg ctggcggcat acatggaacg cgcgcgaatc agttttcccg tgccataagc
    13141 gcttacgaca ccgatcagca agggataaat catctgtccg ctcatggaaa actccaccac
    13201 catcaccagg gccgtcaggg gggcctgggc agctacggcg aaaaaggacg ccatccccac
    13261 catcgcatac gccaccgtat ggttgccctc cattcccagg gacgtcagaa ccgtactgaa
    13321 gataaaaccc accatgctcc ccacgtacag ggtgggcgtc atggctccgc
//
