LOCUS       c00005_gnlPro..        14567 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDMHFJBG_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 10:05:09
            Original ID  :: gnl|Prokka|MDMHFJBG_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14567
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14567
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[88:4567]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      89..4567
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14567
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14567
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(89..2935)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1"
                     /sec_met_domain="Beta_elim_lyase (E-value: 5.3e-10,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 3e-178, bitscore: 586.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(3031..3411)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_2"
                     /sec_met_domain="GCV_H (E-value: 3e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3482..4567)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3"
                     /sec_met_domain="GCV_T (E-value: 7.2e-87, bitscore: 284.4,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 6e-23, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPKTFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPTAYAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4643..5764)
                     /locus_tag="ctg5_4"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPAGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(5823..6746)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_5"
                     /sec_met_domain="Peptidase_S11 (E-value: 2e-55, bitscore:
                     181.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGKVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             complement(7306..8433)
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSTVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWTGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGITVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLPPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGRDVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCSPAGASTPPLPTLEEKEILHAIRLGFNTIDTLCTSL
                     EKAAHTITPLLAKMQIAGQITPDAGGYFSINGREL"
     CDS             complement(8430..9542)
                     /locus_tag="ctg5_7"
                     /transl_table=11
                     /translation="MKIVHLVPSMESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPR
                     LEKEGSRHILMPIGKKSISTLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPP
                     EDRPGLVTSVHGFYSVNRYSAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAI
                     SPDQYHPAYSPSREWLMGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGI
                     PAHAVIVGEAKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKS
                     PEAFGKSTLEALALGKPVAGYAHGGVKEQLDAFLPEGNVAVGDTAAMADLLARWHTQPP
                     PLPRQIPSPYNMQDMIQAHLDVYQELTPYS"
     CDS             complement(9539..10555)
                     /locus_tag="ctg5_8"
                     /transl_table=11
                     /translation="MNKSMPPTKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHL
                     NQSLGLAQALISKAGGTVETVDLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLI
                     CARHHFKTRAVLCMKPTLPCSFFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPS
                     VPKDTTLILIGGPSKDFDWDDESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAV
                     PELTVVPVEETRPGWVARHLAHASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRK
                     SRILSGLETLEKEGMVTGYSDWKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10565..11626
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.5; E-value:
                     1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_9"
                     /sec_met_domain="Fer4_16 (E-value: 3e-20, bitscore: 66.5,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLTPDSSVIKDSLCAVSRQLGFSGCRVARAEKSPHAEKLFQWLER
                     GWHAGMEWMARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSICLYAHGKDYH
                     GILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRRKGGSRF
                     FIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTIEHRGAI
                     PEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSLDAGGFA
                     ALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHASWAVERILR
                     RHGRHASSSGARD"
     CDS             11745..12122
                     /locus_tag="ctg5_10"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             12156..12707
                     /locus_tag="ctg5_11"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             12743..13354
                     /locus_tag="ctg5_12"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRFLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13485..14252
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_13"
                     /sec_met_domain="HAD (E-value: 3e-35, bitscore: 115.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYIFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVDVNNVKSMTC"
ORIGIN
        1 cttcggattc gaaatccgat tcttgaacat aagaaaaagg ctgctccaaa tgaatggaac
       61 agcctttttg aaaggaagga tgagattttt ataactctac ggccttggag aattcctcca
      121 ccgtgtcgca ggtgcagacc agattgcggt ctccgtacac attatccacc cggcctacat
      181 acggccagaa tttgtgaata aggagaccgg agaccggata agccgcttca ctgcgggagt
      241 aggggtgccg ccattcgtcg gcagagacca tttctgcggt atggggcgag tttttcagga
      301 cgttgtcttc cttgtctgcc gtaccgttga taatggccgt gatttccgca tgaatgcgtt
      361 ccatggcttc aatgaagcgg tccagttctt ttttgggttc cgattccgtc ggctccacca
      421 tcagggtgcc cggaacgggg aaggacatgg tggggccgtg gaagccgtag tccatgagcc
      481 ttttggcaat gtcatccacc gtgaggccgg cgtcatgagt gagctgacgc ggatccagaa
      541 tgcattcatg cgccaccagc cccttgttgc cggagtagag aaccgggaag agatgtccga
      601 gtttcttggc aatgtagttg gcgttaagga tggccatttc cgtggcttcc ctgaggccgt
      661 ccggccccat catggagagg tacatccagc agatggcggc gatggaggcg cttccccacg
      721 ccgcagacgc tacggcccct tcttcatggc ccagcgtgag gtgcccgggc aggaagggta
      781 cgaggtgttc cgctacgccg atgggcccga tgccgggacc gccgccgccg tgcggcatgg
      841 caaaggtttt atgcaggttc aggtggcaga cgtccgcgcc aatgcagccg gggcaagtca
      901 gacctacctg ggcattcatg ttggcgccgt ccatgtacac ctggccgcca ttggcatgga
      961 cgatgtcgca gagttccttg attgtctgtt catatacccc gtgtgtggag gggtacgtga
     1021 ccatgatgca ggagagattg tccttatggg cttccgcctg ggatttcagg tctgccatgt
     1081 cgatgttgcc tctttcgtcg catttgacgg gcaccacctt gaggccggcc atggcggagg
     1141 aggcgggatt tgttccgtgg gcggaggtgg gaatgaggca gacattgcgg tggccttctc
     1201 cggcgtgctt ctggtagcgg cggatggcca gtagcccggc atattcccct gcggcgcccg
     1261 cgttgggctg gagggagacg gcggcaaagc cggtgatttt cgccagacgg tcggacagga
     1321 cggagagcat ttcccggatg ccttccgact ggtccgccgg aacaaaggga tgcagggagt
     1381 tggcttccgg ccacgtgatg ggaatcattt cagaggcggc gttcagcttc atcgtgcagg
     1441 agcccagagg gatcatggct tcatttagag ccaggtcccg ggattccagg cggcggatgt
     1501 agcgcatcat ttccgtttcg gaatggtagg agttgaaagc cttttccgtg cagaaaggcg
     1561 tctggcgcgt gtggacggga tcccaggcag gagcgtcgca atcgcaggcg gcggatgttt
     1621 ccgcacctgc aagggcggag gccagtgccg ctatatccgc acaggttgcg gtttcatcca
     1681 gagagatggc tgcgtggtcg gcatccaccc tgcggatgtt atacccggct tccagggctt
     1741 tttgcaccat ggcgtccgct tgtccgggaa cggaaagcag cagggtgtca aagaagtttt
     1801 tgttttcaat ggcgatgccg gcttccgtga gcgccttgta caggcttttg gttttcaagt
     1861 ggatttccgt gccgatgcgt ttgaggcctt cctgtccgtg gtatacggcg taaaaggcgg
     1921 caagcacggc caggagcacc tgggcggtgc agatgttgga ggtcgccttg tcgcggcgaa
     1981 tatgctgttc cctcgtttgc agggccaggc ggtaggccgg gcggcccagg gtatctatgg
     2041 acatgccgat aaggcggccg ggcatgcggc gtttgagagc gtccgtgcag gacatgtagg
     2101 cggcatgggg gccgccgaag cccattggga tgccgaagcg ctgcgtgttg ccgatgcaga
     2161 tatcggctcc gaaggcgccg ggttcccgga tgacggtaag ggccatgaga tccgccgcca
     2221 cgacgcagag cgcgcccgtg gcatgcacgc gggaaaagaa gtccgtgtag tcgcagatgc
     2281 ggccgagcgt gtccggatat tggacaagca ctccggccag atccgcaccg atggatgcgg
     2341 ggtcaaagga tgagcaatct cccacgatga tgttaacgcc ctggaaggcg gcgcgggtac
     2401 ggatgacgct gatggtctgg gggtggcagg tgtccgccac aaagaaggtg tttgctttgg
     2461 ggcgcgcatt ccggcacatg gtgacggctt ctgctgctgc ggtgccttca tccagcaggg
     2521 aggcgttcgc taccggcagt cctgtcaggg aagagaccat ggtctggaaa ttcatgagca
     2581 tttccagccg tccctgggcg atttccggtt gataaggagt gtaggccgtg taccagccgg
     2641 ggttctccag tacattgcgg aggatgacgg agggagtgat ggtgccgtaa tagccctggc
     2701 caatgaaggt tttcaggagc ttgtttttcc gcagaatgga acggagttcc tctagggctt
     2761 ccgtttccga tttggctgcg ggcaggtcca gcggggcctt catgcggata tctgcgggga
     2821 cgatgtccgc aatgagttcg tcaagcgtcc ggtagccgag gctgtcaagc atttcccggc
     2881 gttcttcccc ctgggggccg atgtgccggc tggcaaaatc tgagtgggta ttcatgtggt
     2941 atctctggct ggtaatagcg tccggccgcg gaacgggcca aacaaaatgc cccgggatgg
     3001 aatcaccggg gcgggggagg gaagaatggt tcaggagcag tattcctcgt aatccgtggc
     3061 gttcatcata tcttccgttt ccgtgggaac gtccaggcgg attttgtaca gccagcctgc
     3121 gccgtagggg tcggagttaa tgagggacgg atcattggaa agctcttcgt tcacttccag
     3181 gatttctcct gaaacggggg tgtacacgtc gctggcggct ttgacagatt ccacgacagc
     3241 gacagggtcg ccggctgcga cggtggcgcc tacttcggga aggtctacaa agacgacatc
     3301 ggagagttcg gcctgggcat ggtcggaaat gccgatggtg ccgatgtccc cgtcaatttc
     3361 aatccattcg tgatctttgg aatacagcag attttctggt acgtcgtgca taagatgtaa
     3421 ttgtttgaag tgagagtgta gtaaaatgag gtgtttgtca gtttattttt gcgccgtagt
     3481 gtcagccttt tttataaaag ggttttttta cgaccacggc tgggaatttc cttcccctta
     3541 cgtcaatttc cagctccgtg ccgaccttgg cataggcggt aggcaggtag gccagggcaa
     3601 tgcccttcat cagcgaagga gagagcacgc cgctggtaag ttctccgatg gcttctccgc
     3661 cggggacgtg cacggcatag tgggcgcggg gaggagctcc cttgccggtg tattcaatag
     3721 cggccagccg acggctgagg ccgttggctt tttgttcccg gagaatatcg gaaccgatga
     3781 agtccgtatc cagcgcgcag aagaatccga gcccggcttc cagaggcgtt ttgtccggag
     3841 agaggtcgga gccgttcaga ggatagcaca tttccagacg caggctgtcg cgggcgccca
     3901 ggccgcaggg tttggctcct gctccaagaa aggcttcaaa ccatttgacg ccttccttag
     3961 ccgggcagaa gaattcaaaa ccatcttccc cggtatagcc ggtgcggcag ataatgagat
     4021 ccgtcccttc cgccgtgatg cgggagattc cattgcgggg gggaagttcc acgccgggga
     4081 tgacgcggga gaatacttct ccgcattcgg gaccttgaac agccagcccc acgtattcgt
     4141 cggagtggtt ttccagggtt acgcctgcag gttgatgggc ggaaagccat gcgaagtctt
     4201 catcaatctt ggaggcgttc accactacaa agaaggtttt cggttccatc cggtacagga
     4261 tgaggtcgtc aatgactccg gccctgtcat tgagcatgac ggagtattgc ccctgcccta
     4321 cattcagttt gttgatgtca ttggtcagca tggagttcag ccatgctgca gcggaaccgc
     4381 cggctaccgt gaactgcccc atgtgggaga tatcaaaaat gccgcaggtt tcgcgcactg
     4441 ctttgtgttc gtccagaatg ccggtgtact gcaccggcat attccagccg gcgaaaggaa
     4501 ccattctggc tcccagttca acgtgtttag ctgccagggg ggtggatttg acgtctgtat
     4561 cagtcatgag gcgatgtgaa ggttatgagc aatctgcccc ttatatcagt aaaagtcaat
     4621 ggaattccgg taacgcttcc gtctagacat tgaagcggaa ttcgatgacg tccccgtctt
     4681 tgacgacata ttcttttcct tcgatgcgca gcttgccgtg ttccctcgct ccggccttgc
     4741 cgccgcagga aaccaagtcg tcgtagtgca ctacctccgc ggcgataaaa ccgcgttcaa
     4801 agtccgtgtg gatgacgccg gccgcctggg gtgcttttgc cccggctgga atggtccagg
     4861 cccgcgtttc cttgattccc gtggtgaggt aggtgcgcag gcctagaagg tggtacacgg
     4921 cgcggataag gtcggaaacg ccggagtcct tcacacccag ggattccagg aattcgcggg
     4981 attcttcctc cgagacgtcg atgagttcct cttcaatccg ggcggagatg acaatggctt
     5041 ccgcgttatg gtgttccgct acgtattttt tcacctggga gacgtaggga tgggcgtccg
     5101 ggttggagat ggcgtccgcc agttcgtctt cattgacatt gcaggcgaaa atgctttttt
     5161 tatccgaaag cagctggaaa gaatggagca gcttgcgttc atcgtcgtcc agctgcggtt
     5221 caagggtgag ggcgggattg ccttcgttca ggtggggcag gagtttggtg atgagggcca
     5281 cttcggcctt ggcttccttg tcgccgctgc gtgccttgcg ttcgcgggaa gagagtctct
     5341 tttccatggt ggcgatatcc gccagaatga gttccgagtt gatgatgtca atgtcgcgca
     5401 gaggatccac ggaaccgagt tcatggataa tatcatcatt gtcaaagcag cggactacct
     5461 gcacgatggc gtccacttca cggatgtttg ccagaaactg gttgcccagg ccggctcctt
     5521 ccgaggctcc cttgaccaga ccggcaatgt ccacgaattc aataagcgtg gggatgattt
     5581 tttcagaacc ggacatgtcg gaaagaacct gcaggcgggg atccgggact gttaccatac
     5641 ccacgttcgg gtcaatggtg cagaagggat agttggccgc ctgggccttg cgcgtccggg
     5701 tgaccgcatt gaataaagtg gatttgccga cgttggggag acctacaata cctgcctgta
     5761 acataggcag gactgatagc gggtcacgcc gtgaaagtca aataccaatt gccgacgggc
     5821 atttatgcgg cggatcccag agcccatctg atcaggtttt ccgattccgt ccagatacgg
     5881 gacggatggc agccgaggac gacgacgatg acatggcgcc cgttgacgcc ggctgaggaa
     5941 accaggcagc gtccggcggc gttcgtgtat ccggttttca ttccggtaac ccaggggttc
     6001 tgggtgagca gcttgttggt gtttctcagc agaagcgttc tgccgttggc gcgggtaaag
     6061 gcatattggc gtttgcagat aatattgcgc agttccgggt tgcggtacac ataataggcg
     6121 cagcgggcca tgtcaatggc agtggaatat tgatccgccg ggaggccgtt gggattggcg
     6181 aagcgtgagt tgtacatgcc catctgccgg gctttggcat tcatcaactg ggcgaaacgg
     6241 ggaacggaac ccgccgtatc gcgggccaga gccagggcta cgtcgttgaa actgcggatc
     6301 atcatggcat tgagcagttc gcggcgtgaa tagacttccc ccgcccggaa tcccagtttg
     6361 gtggggtccg ccttggtatc ggaaggctgg atgaccactt ttttgtccag gctgccgtgt
     6421 tccatcacga ccatggccgt cacgagtttt tgcgtgctgg ctacctggcg gtgctggagg
     6481 ccgttgtggg aaaagagcac tttgccggta agggcgtcca tgacgcaggc gctggcgcag
     6541 cggggcgtgc gcggggcgct tgaggggatg gctacaggac gtgtggggaa attggccggt
     6601 cgggggaggg catgggaaac cggctgggag agttgtgggg gaacgggcgt tgcgaggggg
     6661 atgtagtcac ttgaatcccc gtacgattgg cagcttgtgg agctcaggca aagggagaat
     6721 cctgcaagaa gggcgaataa acgcatgtct tgttgctaca gtaagaagtt tcgttcatca
     6781 agcccaaact ccgcatttga aagagagccg gacgaaaaag gccgcggatc ggacaatccg
     6841 cggccttttt tctctattaa ctacctatgg aaccaaaaac caccctgaac ggattttgaa
     6901 ttgctttttc catccgtcgg acagatcttg tgaaggatga gactccaggc aggagggatg
     6961 cgttcaaaat atattcgtca acagttcttt ttaagaggtg ttgccgtatg agcccgagcc
     7021 tgcgtccagt aaatatggca gagatttttt ccgaatatat tttgtttttc gcgagcatgt
     7081 aaatttgccg caggcattta aaatgccggg gatgtcctgc cgatatattt aatttttgga
     7141 ataaaattat tgaaggaaag gatttggcga ctgttttaag acgttttttt gcatccggat
     7201 ggaaaggttt ttatacggga gatggacggc gctcccttcc ggttccatgg tcagggagag
     7261 gaggcccgga cctggcgttt tccccggcgg aaaagcggaa tctgcctaaa gttccctgcc
     7321 gttaatggag aaataccctc cggcgtccgg agtaatttgc cctgcaattt gcattttggc
     7381 caaaagcggg gtgatggtat gcgccgcttt ttccagagag gtgcagaggg tgtcaatagt
     7441 attgaaaccc agtctgatgg cgtggagaat ctccttttct tccaaagtgg gaagcggtgg
     7501 ggttgaggct ccggcagggg agcatggcga gaagagaggc agtccctgtt ccggaacggc
     7561 ccagttcatg tcctgcagaa tatcggaggc tccggtagct aggatggctc cgtcccggat
     7621 gagggcatgg catccgtcgg aagaatgccg gtcaaccggt ccgggaatgc aaaaaacgtc
     7681 tcgaccctgt tcggccgccg ttcgggccgt gatcagggcc ccgctgcgtc cggacgcctc
     7741 caccaccagc gtagcgcggc tccagccgct cacgatgcgg ttgcgcatgg gaaaagtggt
     7801 gcgggagggg ggcaggtcca tcgggaactc ggagactacc gctccatgcc cgtccgcaat
     7861 gcgctgcgcc aagtttctgt tttcccgagg atacagtttg ttgagacctg ccccgataac
     7921 ggcgatggtg cgcccctccg cgtccatggc cccggtatgg gcttccgtgt ccacgccgcg
     7981 cgccagtccg gaaatgacag ttattccggc ttccgccagg tcatgggaga tgtttctggc
     8041 gcaaagcctg ccgtaatggg tggccatccg tgagccgacg acggcaatgg agcgttcggc
     8101 atccgttccg gtccagtttc cccaggagta gaggacaatg ggcgggtctg ggagagcacg
     8161 cagggaggat gggtaggagt cgtcaaaaac cgtggttacc gcggcccccg cgttatccgc
     8221 cagttccagt tccctgtacg ggttgacggt gctccgccaa gaggaaatgc ggcaagccag
     8281 ctgcgccccc acgccgggaa tttccatcaa cagggaggaa ggggattcca gaatcagttc
     8341 cggagaggcg aatacctgca ggagacgcat gattctgaca gggcccaggc ccggtatcag
     8401 gttcagggct atggctgctt cccggggtgt catgaataag gtgtcagttc ctggtaaacg
     8461 tccagatggg cttgaatcat atcctgcata ttgtaagggg aaggaatttg ccggggcagg
     8521 ggggggggct gggtatgcca gcgggccagc aggtccgcca tggcggcggt atctcctacg
     8581 gcgacgttcc cttcaggaag gaaggcgtcc agctgttcct tgactccgcc gtgggcgtat
     8641 ccggctacgg gtttgcccag ggcgagcgcc tccagggttg atttgccgaa ggcttccggg
     8701 cttttggtca gggagagggt gacggaacat gtggaaagga tttccctcag atcctggcga
     8761 tggcctgtcc aggtgaagga ctgggagacg ccggaacgtt ctattgcccg caggacctcg
     8821 tttttatatt cttcttttcc cttctttgct tctcctacaa tgacggcgtg ggccgggatt
     8881 ccctgttcca gaagctgcct gacgaccgga atcagatcca gatgcccttt caggcgcgtg
     8941 atgcggcccg gcaggcacag ggtgaatttc cccttcagtt caggatagga catgaaccag
     9001 cccatgagcc attcccggga gggggagtag gccgggtgat attggtccgg ggaaatagca
     9061 ttgggtatga ttctgatatg gtccggaggg gtggacggat aatggtcaag gatgtagtcc
     9121 ctgatgcagt tggagacggc gatcacccgc tctcctcggc tcatgatggc ggagtaccgg
     9181 ttgacggagt agaagccgtg aacgctggtg acgaggccgg ggcggtcttc cggcgggagc
     9241 tttttccatg ccaggtagcc tgcccacgca ggaacgcggg aatggagatg caggatatcc
     9301 ggcctgacgg cctgaagcag ggcgcggagg gccccgatgc ggaagagagt ggagatgctt
     9361 tttttgccta tcggcatcag gatgtggcgg gagccttcct tttccagacg gggcaccagg
     9421 cgtccgcctc cggaaacgac gatattttcc acgccccggg aagaaaggcc gctgcccagt
     9481 tccataacga cttgttccac gcctccggat tccatggagg ggacgagatg tactattttc
     9541 ataaggcgcg gagctgaggg aaaaatctgg agaggatgta gtctgctgca cggtccgctt
     9601 ccagaagcgg ggaaccggga gccgtcaggc ggaagttctg ttttttccag tcactgtatc
     9661 cagtaaccat gccttccttt tccagtgtct ccaggccgga caggatgcgg gatttgcggc
     9721 tgccgtgtcg gcgcggtacg gaaaggatgc ctacaggcgc gccggagcca agagcctcat
     9781 ataccatgga gacgctgtcc tggctgaccc aggcggcgga ggcgtgcgcc agatgccggg
     9841 ctacccaccc cggccgggtt tcctccacgg gaacgacggt tagttccgga acggccgtcc
     9901 ggattttttc cgcaaagccg tccggcgtcc ggcgcgaggt ggttagaaca aggtgtccgg
     9961 gggtgtggat gctgatggac gcgagctggt tgagcatgct ttcgtcatcc cagtcaaaat
    10021 ctttgctggg ccctcctatg agaatcagtg tggtatcctt tggtacggag ggatccggcc
    10081 tcatggggtg gagagctccc tgggtgggga agatatccgt atccgtgtaa tcgcggccgg
    10141 aatccaggtc atggcgggga ataaggcaga ggtcgaaaaa ggaacaggga agcgtaggct
    10201 tcatgcagag gacggcccgg gttttgaaat ggtgccgcgc gcagatgagc gggatatgcg
    10261 ttgcatgtcc ggcggaaatg aacagatccg gccgtggaat gtcgctgcct gtgacgacct
    10321 tccggatttt ccccaaaagg gaaagcccct gcaggtctac cgtttccacg gttccccccg
    10381 ctttggagat cagagcctgc gccagcccca gggactggtt gaggtggccc tgtttcccat
    10441 cgctcagaat ccggatgttc atatatgcgg cattatgaag cggcggcggg gtgcaggcaa
    10501 tccaatttcc accggacaga agaaaattct tggtgggagg catgctcttg ttcatgattc
    10561 cggcgtgctg actccggatt cctctgttat taaagattcc ttgtgcgccg tgtcccggca
    10621 gcttggtttt tccggctgcc gggtggcccg tgcggaaaaa agcccgcatg cggaaaaatt
    10681 gtttcaatgg ctggagcgcg gatggcacgc cgggatggag tggatggcgc gttccccgga
    10741 gcggcgcacg gatcctgcgg aagtgcttcc cggatgccgt tccgtcattt gcctgtccta
    10801 tgattatgac agccccggta ggcgcccgga gggggagggt agcatttgcc tttacgccca
    10861 tggaaaggat taccacggaa ttctggagga aaaactggcg gatttgcagg agctgctttc
    10921 catttacggc gggaagcaga gggggtatgt ggactccggc cctgttatgg aacgggacca
    10981 tgcggaggcc tgcggcctgg gctggcgcgg gaaaagcggt ttgatcgtgc gcaggaaagg
    11041 gggctcccgc ttttttatcg ctaccctgct gactacgctg gaactggaac cggacgctcc
    11101 ggtttcaaac ggatgcggca gttgccgccg ttgtgcggcc ctgtgtccga cgggcgcaat
    11161 tatggaaaac ggtcaggttg atgccggacg ctgcctttcc tactggacga ttgaacaccg
    11221 gggggctatt ccggaagaaa tccgtcccct gataggcacg cgcctgtacg ggtgcgatac
    11281 ctgcgtgacg gtctgtccct ggaatggtaa gcctttgccg gacgttgacg aacggttccg
    11341 catgtcccgt ctgctggctt ccattcccct gcgtggtctt ctttccctgg atgccggcgg
    11401 ttttgcggcc ctgttccgga attccccgtt gaaaaggctc aagagggaag ggctgctgcg
    11461 taacggctgc gttgtgctgg ggaatgcggg gactccggat gacattgatt ttctgaaggc
    11521 gctttacggg gagtctcctc tggtggagga acacgcttcc tgggctgtgg agcgcatcct
    11581 ccgccgccac gggcggcatg catcttcaag cggtgcaaga gattaaaaat agaaaaaatg
    11641 atgttttggt cttgtcaaaa cctcaattta tggtatccat cttgccccaa gcaatagctc
    11701 tgcgcgaggc agagaaaaat aacagctagc aaatccaatc cattatggca cgccttttcg
    11761 gtacagaaat acccaacgag aagcgcatcg aggcttccct tccgtatatt tacggaattg
    11821 gtcgctcgac ttctaagaga atcctggaac aagcaggcat caatcccgac atccgcacgg
    11881 gacagcttac cgacgaacag ctcacgaaga ttgttcaagt aatcaccacc gacggcattt
    11941 tgattgaagg tgaccttcgt cgtgaaaagc aatccattct caagcgtctg acctccatca
    12001 actgctatcg tggtcagcgc caccgccgcg gccttccggt acgcggtcag cgtacccgca
    12061 cgaatgcccg tacccgtaaa ggcaagaaga agaccgttgg cgcgcaggcc aagaagaagt
    12121 aatccgccaa cctgaatttt taatatagct ttactatggc tagcgaagaa atcaccaacg
    12181 aaaccgccga acagcctgtg gaagcggcag cttccgctcc cgtcgctgaa actccggccg
    12241 ccgctgtttc cgctcctgaa gaaatcaaga agcccgaacc ccgcaaggat atctttgcgg
    12301 aacttggtct gggcggcgat gatgacaagc ccaaaatcct gaaggccaag ggcagcaaaa
    12361 acgtttccac gggcgtggtt cacgtttcct ccacgttcaa taacaccgtc gtaactgtga
    12421 ctgaccagcg cggcaatgtc atcggctggt cctccgccgg caagatgggc tttaagggtt
    12481 cccgcaagag cacggcctat gccgggcagg tggtgtgcca ggacgcctgc cgccaggcca
    12541 tgggtcacgg cttgcgtgaa gtggaagtgc gcgtaaaggg gcccggttcc ggtcgtgaat
    12601 ccgccgtacg tgccgtgcag acgatcggta ttgaaatcac ctccatcaag gacgtgaccc
    12661 ccatccccca caacggctgc cgtcctccga aggcccgccg cgtctaattg agaatctttt
    12721 acctatatag atctaatata tcatggctcg ttataccggt ccccgcgata aagtgtcccg
    12781 ccgttttggc gttgcccttt tcggttccac caaggctctt gaaaagcgcc ccttccctcc
    12841 cggccagcat ggcatgcgcg ccggccgcaa gaagaaatcc gactatggcg tgatgcttgc
    12901 tgaaaaacaa aaactgcgtt tccagtacgg tgtgcttgaa ggccagttcc gcaagtatta
    12961 tgcagaagcc gcccgccgcc gcggcattac cggcgatatt ctgcttcagc tccttgagct
    13021 tcgtctggac aatgttgtgt accgcctcgg cttcagcaat acccgtgccg gcgcccgtca
    13081 gcttgtttcc cacggtcaca tcaccgtgaa cggcaagaag acgaatatcg cgtcctactc
    13141 ctgccgtccg ggcgacgtca ttgccgtagg cggcaaggct tcttcccagc agctggttac
    13201 ccgtttcctt gacctgactc aggctactgt ggttcctgac tggctggaat gcgaccgtga
    13261 caagctcacg ggcaagattg cccgcgtgcc ttccaaggaa gagattgctc ccatcgtcaa
    13321 cgagcagctc atcgtggaat tttactcccg ttaatcttat ttccttctgg atttgcttca
    13381 aaaccccggt tgcctttcgg cggccggggt tttgggcatt caggaggagg ggcatggaag
    13441 agttgggtgt tgagagttaa gggaagcggg tataggatga aagcatgacg gacgattgga
    13501 aaaaaagagg cgcagcgctg tttgatatgg acggcacgct ccttccctgg gatacgcaat
    13561 atattttttc ctgttttgtg gtgaggcgcc atccttggag acgcttgctg atttttcttt
    13621 tcctggcctg tattccgctc tatattttga gaatatggga tgagaaccgg atgaagaggg
    13681 cttatctcat gtatttgtgg gggcttcccg ctgaaacggt gcgggaatat ggacggaagt
    13741 ttgccgagat ggcgcaggaa tggatttatc cggagctgaa ggagcggctg gcagggtatc
    13801 ggaagaaggg ttatttgtgt ctcatggttt ccgcttctcc atcattttac gtgaagcccc
    13861 tgggcgaact gctgggattt gacgaagttc tgggaacgga tgtgcttctg gaggaacgca
    13921 tgccggcaat gccggaactg ccgaacggta ataataaggg ggcggtgaag gtggagcgtc
    13981 tgcgggagcg gaatgtactg ccggaacatg gtgttctgga aaacgccgtt gcctacagcg
    14041 acagtgccgc ggatctgccc atgctgcttt cctgcaggcg gagggttctg gtgaatcctt
    14101 ctcctgccct gaaagaagac aggcttctgg atggtgcgga gtgtctgtat ccggccaggc
    14161 cttggaaggg aaggtttggc aagatatgga gaattggatt ttttgtcatg gggttggtgg
    14221 atgtaaataa tgtgaaatca atgacttgct gatttatcaa gagaaaattc tttacttttg
    14281 tgacgaaaat gtttcacttt tcttaacaag gggggaaaaa gcatttttct ttccatgtta
    14341 gcaaatcaac aattaatacc ctaaccaagt aatagtcatg caaaccaaga acatcatcag
    14401 tgttgcggca gttgtggcat cctttgctgg agctgctctt gcgggtactc ccgtcaagat
    14461 tgttgctccg actccggttc ccgctcctgt ggcgacttcc agcccgctgt ccggcgatat
    14521 ttacgccggc tacgcttcca attacacctg ccgcggcatt gtggctt
//
