LOCUS       gnlProkkaEPJBAJGM_35   10611 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EPJBAJGM_35.
ACCESSION   gnlProkkaEPJBAJGM_35
VERSION     gnlProkkaEPJBAJGM_35
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 06:12:51
            Original ID  :: gnl|Prokka|EPJBAJGM_35
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10611
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1263)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_1"
                     /sec_met_domain="Polysacc_synt (E-value: 1.3e-29, bitscore:
                     94.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLKIIHNVLAKGGLTIFNLILPLAVMPYIYRVLDPHDLGMIEYA
                     TAIVTYFSIFGMLGIYNYGLREMSSIRNNLNSCAFLYRQLFTIGVLSNIFSATCLLLLS
                     FFMDKLVKDIVYIQLLLIVSQIFYVEWVNEAFERYSFITLKTILVRGLGYLSIFGLVTS
                     SNDYKTYVWILSITVFINYFISYLYVKKKLPIESVQVDWNFIKKIIFALFLILLLNNTN
                     LLYTLLDRFMLGLKSDIYVAYYGVGQKLSDMLKAFLTIVVVVTIPRMSLQLNQNKERYL
                     ENINHLISFLFLLTLPIASLFFCLSKEIVILFAGENYLEAIPSLKIFAIRIVVIVLEAV
                     LYNQIIFLYRREKDLLKLNALCGCLNLGLNGVLYSFLNPFLAILTTLVSELVFQILCIY
                     YIRTKIGLYITYAKKSHLLYLL"
     protocluster    1..10611
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1323:5611]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1324..5611
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10611
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10611
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(1324..2034)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-16, bitscore:
                     52.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTAVIMAAGMGTRFGKYTEQIPKGFVEVCGKPMIERSIETLIS
                     CGIERIVIGTGYKHEVYDFLKKKYPMIETCFSPLYAETNSMYTLYNTQGLIGSDDFLLL
                     ESDLVFETKAITELMNCGKPDVMLATPITKFQDQYYVEFDTKHHLTACSTQKENLNVKG
                     ELVGIHKISSTFFKEMCKDYGRILSEQPKLGYEYELLRISMSTLPLFVLVVEGLKWYEI
                     DDLMDLAYAEIFFK"
     CDS             complement(2047..3165)
                     /NRPS_PKS="Domain: Aminotran_5 (31-334). E-value: 3.5e-31.
                     Score: 100.3. Matches aSDomain:
                     nrpspksdomains_ctg35_3_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 67.4; E-value:
                     1.8e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_3"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.4e-07, bitscore:
                     20.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 3.4e-29, bitscore:
                     93.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIKRNILLNPGPATTTDTVKMAQVVPDICPREKEFVGMMKTLRT
                     NLLKVAHGIPGKHTAVLFCGSGTINIDVCLNSLLPKDKKVLIINNGAYSDRAVEVCRYY
                     GLSHINLRFSVYERPDLHEIESILKKDSDIFLVYTTHHETGTGLLNPIREIGALAHRYG
                     CVFITDTTSSLGMIPFDIEKDNVDFCMASAQKGLQSMTGLSFIVGNEEIICKSKEYPKR
                     SYYCNLYMQYEYFEKTGEMHFTPPVQTIYATCQALKEYFEEGEENKFARHRRVFDAIHS
                     GIEELGFKYVIDKQWQSGLVVSVLYPNHPNWNFDKVHNYCYERGFTIYPGKITTTNTFR
                     LCALGAIDESDIKSFFSVLKDALEHFNINVFY"
     aSDomain        complement(2164..3072)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_3_Aminotran_5.1"
                     /evalue="3.50E-31"
                     /label="ctg35_3_Aminotran_5.1"
                     /locus_tag="ctg35_3"
                     /protein_end="334"
                     /protein_start="31"
                     /score="100.3"
                     /tool="antismash"
                     /translation="REKEFVGMMKTLRTNLLKVAHGIPGKHTAVLFCGSGTINIDVCLN
                     SLLPKDKKVLIINNGAYSDRAVEVCRYYGLSHINLRFSVYERPDLHEIESILKKDSDIF
                     LVYTTHHETGTGLLNPIREIGALAHRYGCVFITDTTSSLGMIPFDIEKDNVDFCMASAQ
                     KGLQSMTGLSFIVGNEEIICKSKEYPKRSYYCNLYMQYEYFEKTGEMHFTPPVQTIYAT
                     CQALKEYFEEGEENKFARHRRVFDAIHSGIEELGFKYVIDKQWQSGLVVSVLYPNHPNW
                     NFDKVHNYCYERGFTIYPGKIT"
     CDS             complement(3170..4300)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 61.2;
                     E-value: 1.4e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.7e-18, bitscore:
                     57.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-21, bitscore:
                     67.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNVEKVYHALLANGIDFFTGVPDSLLKDICAYITDHTFKEQHVI
                     AANEGTAVSIAAGHYLASGNLSLVYMQNSGIGNAVNPLLSLADKKVYSLPIILMIGWRG
                     EPGVKDEPQHEKQGEVTLDLLNAMQIPFVILNAEEDKALRQIHDIIISAKDKSIPHAII
                     IRKNIFGKYKLLNEQKNDCPLSREEALKLVVDYLEATDLVVSTTGKLSRELFEYREAEG
                     EGHECDFLTVGSMGHSSSIALGIALANSERRVFCLDGDGAFIMHMGAIGNIGYLSPKNY
                     FHILFNNGSHESVGGQPTIGFQLDIPAIAKACGYRTVFSLTTKDEIKEILQQTKIMEGP
                     VLIELKVKVASRDDLGRPTTTPLENKFHFMEFLKNK"
     CDS             complement(4310..5611)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 220.3;
                     E-value: 5.2e-67)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="CTP_transf_like (E-value: 4.1e-12,
                     bitscore: 37.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.3e-121, bitscore:
                     396.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 9.2e-65, bitscore:
                     209.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKQIYIGMTADIMHPGLINIINEATKFGDVIVGLLTDKAIAEHK
                     RLPYLTYEQRKKIVENIKGVSKVVPQEEWSYINNLKRLKPDYIIHGDDWKTGVLCEIRE
                     QVYDVMNKQGGTVIEIPYTQGINSSSLNRDIKSIGTTPDVRMKTLRRLINAKSIVRILE
                     AHDGLCGLIIENLEIQKGDRLEVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKIGLKKNSLFGTDAIQTQDT
                     IEGFCNKIKAGKEAQVTNDFMIIARIESFIAGKSMCDALERAYAYVEAGADGIMIHSKN
                     KSGEDIKEFCITFRQKYAHVPIVVVPTTYDHIYESELHTWGVNVVIYANHMLRAAYPAM
                     LQVAKTILENERAKEVRPLCMPIKEILELIPGTK"
     CDS             complement(5691..6302)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_6"
                     /sec_met_domain="Epimerase_2 (E-value: 9.5e-60, bitscore:
                     193.7, seeds: 187, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVDKIKSDKRLDEELKGILKTAGYDINRLLDGKKLVLITGHRRE
                     NFGDGFVSMCRAIQTLTKKYPNVDFVYPMHLNPNVRKPIYEVFGEDLSNLGNMFFIEPL
                     EYLSFVYLMEKSTIVLTDSGGIQEEAPGLGKPVLVMRDTTERPEALEAGTVKLVGTNYD
                     KIVKEVSALLDNKAHYEEMSKAVNPYGDGTACVRIVNILE"
     CDS             6402..7031
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MITGNTPCYHSIHLLRPRAIYIMSSKSRLYMSHWNLLIKSSQCRS
                     RRSGCITMNQNNIWLYLFQNITHTYQNTSCHIIQILSWFHNIQIIIRNDFKYMQYLIKH
                     FAMLTGNTYDCLELLRIFLKFFHQRSHLYGFGTSPENQHNLLHAISYLLFLVNSAKVKN
                     YFPIIIWQGFKYRMSNQKNDDISLLIGFFIICKFKYIVFLHIRFHY"
     CDS             complement(6858..8063)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152:nucleotide sugar dehydrogenase (Score: 385.1;
                     E-value: 6.1e-117)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MKACFMGLGYIGLPTAIIAAKHGIQIIGVDINPKVVEMTNQGKLH
                     IIEPGMQELLQEVVTTGQLKASTTPEVSDAYFMVVPTPFKGNHEPDISYVEAATRAVIP
                     LLKEGDLYVIESTSPVGTTDKMCDLIFGLRPELRDKIYIAYCPERVLPGNVIYELVHND
                     RVIGGLNEASTDRATEFYSKFVRGTLHRTNCKTAEMCKLTENSSRDVQIAFANELSLIC
                     DKAGINVWELINLANKHPRVNILQPGCGVGGHCIAVDPYFITAEFPMESKIISTAREIN
                     NYKAFWCAEKVQNAMLKFELEYHRKPTIAMMGLAFKPDIDDLREAPAKYITTKVMQSCN
                     NADILVVEPNVQEHNVFKLTDYKEAYEKADIVVFLVAHSVFKSLPYNDRKVILDFCGIY
                     KK"
     CDS             complement(8641..9174)
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MTEQQKYWFAARTRDKQEFTVRKSLDRLKSEEHLDLDYYLPTRFV
                     ISQLKYRRKRSEVPVIRNLVFVHSTKQTACDISNIYNVPLFYMKDLATHSMLVVPDKQM
                     EDFMFVMDLNPDGVSLDSEILTVGHKVKVIKGELSGIEGEVAIEANKTYVVIRIKDLLT
                     ASIKVPKSYLKIIG"
     CDS             complement(9175..9396)
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="MGIFLLNILLVQKIRLIFASIKRTFIGHFYESNIFFNSLLSLQKC
                     TIRFGWENVSFKPRSAPGTELIHSKENS"
ORIGIN
        1 caataaatat aacaaatgcg atttctttgc ataagtaata tacaatccta tttttgttct
       61 tatataatat atacacaata tctgaaaaac aagttcactt accaatgttg tcaatattgc
      121 cagaaaggga ttcaagaatg aatataaaac accatttaac cctaaattaa gacatccaca
      181 taaagcattt aacttgagta aatctttctc acgacgatat aaaaatatta tttgattata
      241 caaaacagct tccaagacaa taaccacaat tcgtattgca aatatcttta aagatggaat
      301 agcctctaaa taattttcac cagcaaataa tataacaatc tcttttgata agcaaaaaaa
      361 taaagaggca attggtaaag ttaataaaaa taaaaaactt atcaaatgat ttatattctc
      421 caaatatctt tctttatttt gatttaattg tagagacatt ctaggtatag taacaactac
      481 tacaattgtt aaaaaagctt ttaacatgtc tgaaagcttc tgcccgacac cataatatgc
      541 cacatatata tcacttttaa gccccaacat aaatcggtct aataatgtat aaagcaaatt
      601 tgtattattc aataataata tcaagaataa agcaaatatt atctttttta taaaattcca
      661 gtcaacttgt acagattcta taggtaattt cttttttaca tataaatagc taataaaata
      721 attaataaaa actgtgatag acaatatcca aacatatgtc ttataatcat tcgatgatgt
      781 tactaatcca aatatagaca aatatcctag gccacgtacc agtatcgtct tcaatgttat
      841 gaaagaatat ctttcaaacg cctcattaac ccattctaca taaaaaatct gagaaacaat
      901 tagcagtaat tgtatataaa caatatcttt tactaattta tccatgaaaa aagacaatag
      961 caacagacat gttgccgaaa atatatttga cagaactcca atcgtaaata attgtctata
     1021 caagaaagcg catgagttta aattgttacg aatcgagctc atttcacgta agccataatt
     1081 atatattccc aacattccaa atattgaaaa ataagtaaca atagctgtcg catattctat
     1141 cattcccaaa tcatgaggat ccaacaccct atatatgtaa ggcataacag ctaaaggaag
     1201 tattaaatta aaaattgtca atcccccctt tgccaaaaca ttatgaataa ttttcaaacc
     1261 catgttaaat atgaacagtt atctatattc aacaaagtaa catctatgga ccttctaaag
     1321 attctattta aaaaatattt cagcataagc taaatccatc agatcatcaa tttcatacca
     1381 tttcaatccc tctacaacta aaacaaagag aggtaatgta ctcattgaaa tacgaagtag
     1441 ttcatattca tatccaagtt taggctgttc agaaagaatc cggccataat ctttacacat
     1501 ttctttgaaa aaagtgctag atattttatg aattcctacc aattcacctt ttacattcag
     1561 attctctttt tgagtagaac aagctgtcag atgatgtttt gtatcaaatt ccacataata
     1621 ttggtcttga aattttgtaa taggagttgc taacatgaca tcaggttttc cacaattcat
     1681 caattcagta atagccttcg tttcaaatac taaatccgat tctaataata agaaatcatc
     1741 actacctata agtccttgag tattataaag tgtatacata ctattagttt cagcataaag
     1801 aggactaaag caagtttcaa tcataggata tttctttttt agaaaatcat aaacttcgtg
     1861 tttatatcct gtgccaatta caatacgttc tattccacaa gatattaaag tttcaatact
     1921 acgttctatc attggtttac cacacacttc aacaaatcct ttaggaatct gttctgtata
     1981 tttcccaaaa cgagttccca tacctgctgc cataattact gctgtcttta tcattccaat
     2041 atggttttaa taaaatacat tgatattaaa atgttctaaa gcatctttca aaacagaaaa
     2101 aaaagactta atatccgatt catctattgc tcctaatgca caaagtcgaa aagtatttgt
     2161 tgtagttatt tttcccggat aaatggtaaa accacgttca taacaataat tatgtacttt
     2221 gtcaaaattc caatttggat gattaggata aagaacagac acaaccagcc ctgattgcca
     2281 ttgcttatca ataacatatt taaaacctaa ttcttctatg ccagaatgaa tcgcatcaaa
     2341 cacccttcga tgtcgtgcaa atttattctc ttcgccctct tcaaaatact ctttcaaggc
     2401 ttggcaagta gcatagattg tctgaacagg aggagtaaaa tgcatttcac ccgttttctc
     2461 aaaatattca tattgcatat aaagattaca ataataagaa cgtttaggat attcttttga
     2521 cttacatata atctcttcat tgccaactat aaaagaaagt cccgtcatcg attgtaatcc
     2581 tttctgggca gaagccatac aaaaatcaac attatctttc tctatatcaa aaggaatcat
     2641 acctaaggaa gaagtcgtat ctgttataaa tacacaacca taacggtgag caagtgcacc
     2701 aatctcacga ataggattca acaaaccagt gccagtttca tggtgagttg tataaactaa
     2761 aaagatatca gaatcctttt ttaatatgga ttcaatctca tgcagatcag gacgttcata
     2821 caccgagaat ctcaaattaa tatgagataa accataatat cgacaaactt ccacagcacg
     2881 atcactataa gcaccattat tgataatcag cactttttta tccttaggta acaaagagtt
     2941 caagcaaaca tcaatattaa tagtacctga gccacaaaac aaaacagcag tatgtttacc
     3001 aggtatacca tgggcaactt ttaacaaatt tgttcgcaat gttttcatca ttcctacaaa
     3061 ctccttctca cgaggacaaa tatcaggaac aacctgagcc attttcacag tatcagtggt
     3121 cgtagcaggc cctggattca acaaaatatt tcttttaatc tgcatatact tatttatttt
     3181 ttaagaactc cataaaatga aacttatttt caagaggcgt agtcgtaggc cttcctaaat
     3241 catcacgaga agcaactttt actttcaatt cgatcaaaac cggtccttcc attatctttg
     3301 tttgctgcaa aatctccttt atctcatcct ttgtcgtaag cgaaaaaaca gttcgatatc
     3361 cacatgcctt tgcaatagcc ggtatatcta attgaaaacc tattgtaggt tgaccaccaa
     3421 cagattcatg cgaaccattg ttgaacagaa tatgaaaata gtttttggga gacaaatagc
     3481 caatattgcc aatagctccc atgtgcataa taaaagcgcc atcaccatct aaacagaaaa
     3541 ctcttctctc tgaattagca agtgctatac ctaaagcaat agaagagcta tgccccattg
     3601 aacctacagt aagaaaatcg cattcatgcc cctctccttc tgcttcacga tattcaaaca
     3661 attcacgaga caacttacct gtagtagata ctactaaatc tgtagcttcc aaataatcaa
     3721 caactaattt tagggcttct tcacgggata aaggacaatc atttttttgt tcatttagaa
     3781 gtttatattt tccaaatata ttttttcgaa ttataattgc atgaggaatg gatttatctt
     3841 tagcagaaat aataatatca tgtatctgcc tcaatgcttt atcctcttct gcattaagaa
     3901 ttacaaaagg aatttgcatt gcattcaaca agtccaaagt cacttcacct tgtttttcat
     3961 gctgtggttc atcttttact ccaggctctc cacgccaacc aatcattaaa attatcggta
     4021 agctataaac ctttttatct gcaagtgaaa gcaaaggatt taccgcatta cctattcccg
     4081 aattttgcat gtaaaccaaa gacaaatttc ctgaggctaa ataatgtcct gctgcaatac
     4141 tgacagctgt accttcattg gcagcgataa catgttgctc cttaaaagta tgatccgtta
     4201 tatacgcaca aatatctttt aagagcgaat ctggaactcc tgtaaaaaaa tcaattccgt
     4261 ttgctaaaag agcatgatat actttctcaa cgtttaccat ataatctatt tatttagttc
     4321 ctggaataag ttccaatatt tctttaatag gcatacacaa aggacgcacc tctttcgcac
     4381 gctcattctc taaaatagtt tttgccacct gcagcattgc aggatatgca gcacgaagca
     4441 tatgattagc atagataacc acatttaccc cccacgtatg caattcactt tcataaatat
     4501 ggtcgtaagt agtgggaaca acaacaatag ggacatgagc atatttctga cggaaagtta
     4561 tacagaattc ttttatatct tcacctgact tatttttact atggatcatt atgccatcag
     4621 caccagcctc tacataagca tacgcgcgtt caagagcatc acacatagat ttaccggcta
     4681 taaaactctc aatacgagca attatcataa aatcattggt cacttgcgct tcttttcccg
     4741 ccttaatttt gttacaaaaa ccttcaattg tatcttgcgt ttgaattgca tcggttccaa
     4801 aaagtgaatt ttttttcaag cctattttat cttctataat tacagcagaa attccatgac
     4861 gttctaaagt acgaaccgta aacacaaaat gttcaatttt gcctcctgta tcgccatcga
     4921 aaataatagg cttagtagta cattccaata tattattcaa atcctgaaga cgagtagtta
     4981 aatctacagc ctcaatatca ggtttacctt tgctcgttga gtctgttaag ctactggacc
     5041 acataccatc aaaaacctcc aaacggtcac ctttttgaat ttccaggttt tcgataatta
     5101 agccacataa gccatcatga gcttccaata tacgcactat agacttggca tttatcaaac
     5161 gacgaagagt cttcattcgc acatcaggag tagtaccaat agacttaata tctctattta
     5221 atgaagaaga atttatccct tgtgtataag gtatttctat cactgtccca ccttgtttat
     5281 tcatcacatc ataaacttgt tctcggattt cacacagaac tcccgtcttc caatcatcgc
     5341 catgaattat ataatctggt ttcaaacgtt tcaaattatt gatatagctc cactcttctt
     5401 gaggaacaac tttagaaacc cctttgatat tctcaacaat ttttttacgc tgttcataag
     5461 tcaaataagg taaacgtttg tgttcagcaa tagctttatc tgttagaagc cctactatta
     5521 catcaccaaa ttttgtagcc tcattaatta tattaatcaa gccgggatgc atgatatcag
     5581 cagtcatccc tatgtaaatt tgtttattca tttttatcta tttatacaaa taatacatta
     5641 tctctcagac gcaaaaattc aatttcaata atattctaat tagaattatt tcattctaaa
     5701 atatttacaa tacgaacaca tgccgtcccg tctccataag gattcaccgc cttgctcatc
     5761 tcctcataat gtgccttatt atccaataga gcagagacct cctttacaat tttatcataa
     5821 tttgttccca ccaatttcac cgttccagct tccagcgctt ccggacgttc tgtcgtatca
     5881 cgcattacaa gtaccggctt cccaagtccg ggagcttctt cctgaatacc accgctatct
     5941 gtcaaaacta tagtggattt ctccatcaga taaacaaaag aaagatactc taaaggctct
     6001 atgaagaaca tattccctaa attggataaa tcttcgccaa atacctcata aattggttta
     6061 cgaacattgg gatttaaatg catcggatag acaaaatcaa catttggata tttctttgta
     6121 agagtctgaa tagcccggca catagaaaca aatccgtcac cgaaattttc acgacgatga
     6181 cctgttatca agactaattt ttttccatct aacaagcggt tgatgtcata accggcagtt
     6241 ttcaaaatgc ctttcagctc ttcatcaagc ctcttatcac tctttatctt atctacaacc
     6301 atgtaaagtg catctattac tgtattacca gtcactgtta tagctgattc ccttacacct
     6361 tcatccaaca gattctgacg actcaaagga gttggagaga aatgataact ggcaatacgc
     6421 cctgttatca ctcgattcat ctcctccggc caagggctat atatattatg agttcgaagt
     6481 cccgcctcta catgtcccac tggaatctgc tgataaaaag cagccaatgc cgaagccgta
     6541 gaagtggttg tatcaccatg aaccaaaaca acatctggct gtacctcttt caaaacatca
     6601 cgcataccta tcaaaacacg agctgtcaca tcatacaaat cctgtcctgg tttcataata
     6661 ttcaaatcat aatcaggaat gatttcaaat atatgcaata cctgatcaag catttcgcga
     6721 tgctgaccgg taacacatac gattgtcttg aactcctccg gatatttctg aaattctttc
     6781 accagaggag ccatctttat ggcttcggga cgagtcccga aaaccaacat aatcttcttc
     6841 atgctataag ctatttatta tttcttgtaa attccgcaaa agtcaagaat tactttccga
     6901 tcattatatg gcagggattt aaatacagaa tgagcaacca gaaaaacgac gatatcagcc
     6961 ttctcatagg cttctttata atctgtaagt ttaaatacat tgtgttcctg cacattaggt
     7021 tccactacta aaatatctgc attattacag ctttgcatca ctttagtagt aatatacttg
     7081 gcaggagctt cacgcaaatc atcaatatcg ggtttaaagg ccaatcccat catggcaatg
     7141 gtaggtttac gatgatattc caattcaaac ttcaacatag cattctgcac tttctctgca
     7201 caccagaatg ctttatagtt attgatttca cgagcggtag atatgatttt agattccata
     7261 ggaaattcag ccgtaataaa ataaggatca accgctatac agtgtcctcc aacaccacaa
     7321 ccaggttgaa ggatattcac acggggatgc ttgttcgcca agttaatcaa ttcccagaca
     7381 ttgattcctg ctttatcaca aatcagagag agttcattgg caaaagctat ctgtacatca
     7441 cgggaggagt tttctgtcag tttacacatt tctgccgttt tacaattagt gcgatggagc
     7501 gttcctcgta caaacttact ataaaactca gtagccctat ctgtagaagc ttcattcaaa
     7561 ccgccaatga cccggtcatt atgaactaac tcataaatga cgttcccagg aagaacacgc
     7621 tccggacaat aagcaatata aattttatct ctcaattccg gacgtaatcc aaatatcaaa
     7681 tcacacattt tatcagtagt acctaccggt gatgtagatt ctatgacata caaatctccc
     7741 tctttcaaca aaggaattac ggcacgggta gcagcttcca cgtaagaaat atcaggctca
     7801 tgatttccct taaaaggagt aggtaccacc ataaaatagg catcactcac ttctggagtt
     7861 gttgaagcct tcaactgacc ggtagtaacg acttcttgaa gaagctcctg catacctggt
     7921 tcaatgatat gcaacttacc ctgattagtc atttctacaa ctttgggatt aatatcaacc
     7981 ccgataatct gaattccgtg tttagcagca ataatcgcag taggcaggcc aatataaccc
     8041 aaccccataa aacatgcttt catatcaata aaagttatct attttttatg atttctttat
     8101 cacactcaaa tcctattcta cttcctcaaa cgggtatgga ttctcttcga tatttttcaa
     8161 ttcttcaatg atttcagttt gttccaaagt caattcatct ctattccaac cttcaataat
     8221 cgcatgagct tcctgaagca aaacttcctc ataaatttcc ccataacaat aagttagtaa
     8281 acggacttta agcaaagaag caggcaactg ctccaaaaca agacaaatcc gattcaatac
     8341 catttgtttc ttttgctcct tatccccatc atcataaata gtagcattat atcccatcaa
     8401 aagagccaga cacaaattcg cctcttcctc aacatcggaa ctttgagcag aaaaaagaga
     8461 atcggactta acaagcactt ccttattcaa ccggcaaaaa ttgtcggaat agaccggctc
     8521 accgtccata ccaagataca tcagctcatg agctgcatgc tgaagctcaa gagcacggga
     8581 agttaaatca ttcattatta tgatatatga taaaaatata agattatact tatttagaag
     8641 tcacccgatt attttcagat aggatttggg gactttgata cttgccgtca aaaggtcttt
     8701 aatacggata acgacgtatg ttttattggc ttcgatggca acctcacctt caataccgct
     8761 gagttcgcct ttgataactt ttactttatg cccaacagta agaatttcgc tatcaaggct
     8821 gacaccgtca gggttcaaat ccattacgaa cataaagtcc tccatttgct tatccggtac
     8881 cactagcatg gaatgcgtgg caagatcctt catataaaaa agggggacat tataaatgtt
     8941 ggaaatatcg caggctgtct gcttggtgga atgaacaaac accaaattac ggattactgg
     9001 aacttcgcta cgcttacggc gatacttcaa ttgtgaaatg acaaaacgcg tgggaagata
     9061 atagtcaagg tccaaatgtt cttccgattt aagtcggtcc agagatttcc ggactgtgaa
     9121 ttcctgcttg tcacgggtgc gggctgcaaa ccaatatttc tgttgttcag tcacttagga
     9181 attttctttc gaatgaatca gctcagttcc gggtgcgctt cgcggtttga acgagacatt
     9241 ttcccaccca aaccgtattg tacacttttg caatgataat aagctattaa agaagatatt
     9301 agactcataa aagtgtccaa taaacgttcg tttaatggac gcaaagataa gccgtatttt
     9361 ttgaactaac aaaatgttta ataaaaatat tcccaaagtg atttctgttt tatattaata
     9421 tgttgaattg cagcattgta cgtctaatat ttaacatatt aaagttctgt tcctttttaa
     9481 cttttatgcc tctacttatt ttcttaaaaa tagacgttta ttaaacgaac gtttaaaaaa
     9541 cacctcatca tttccaatat atcattctac attccaatat cttaccctca taaatgtatt
     9601 attgaagttt cgtaaatata cctactgata aatgggaatt tatcgcacag aacgcaagtg
     9661 aaataaaagc ccacttccat aacctatgga gagagtgaaa gcccatggat ttctatctaa
     9721 aacacaagca ttcctttgct tttcaccctt gcttggtcta ctgttgcata aggagttagt
     9781 gacgcctaac ggccatgaac aaccctgcta atggccatga agcaatcgtt taacgaccat
     9841 aagcagggtt gttcatggcc gttaggcgtc actaactcca aggcttttac agatgaagta
     9901 cgtagcccgc gcctattgcg cacaaggtgc aaacgtattg tacagcaact taaaagacat
     9961 cagactccac tattcatagt cgggcaaact cgaaaatgca ggaaaactac actgaccgat
    10021 ttatgtaacc cacgcgcggt attatattaa agaacaataa gttacgacaa aactcagacg
    10081 ttttcggcag gtggaagcaa attttgcttc caccttttca ggttgcttcc accgcagggt
    10141 aaatgccgat ggatagggag atgcaggagg cgggtggaag tgtggaagca aagcagatgc
    10201 aaatttatgt ttcagcacca ccactcaagt tttaaaaaag atgtagtata aagacataat
    10261 atataataag tgttataaat acacacttta taccccgtta ctcttgcaaa tgtcgaaaaa
    10321 gtccgtacct ttgcaatgtg tttttcatag tattagattt aaggttaaca aaggttggag
    10381 tacagcggta ctcctttttt tatgcccata cgtaccgtcc cggttctcca ataaaatttt
    10441 cacataaaat gcaaggcaac tttttatatc catttagttt ttggctatct ttgcactgct
    10501 tttggcgggc ataggcacgc ataaagcagc ttaactaaca ataaatcaat aattaaaaac
    10561 agaaaattat ggcaatgcat acatggtttg aatgtaagat ccgttacgag a
//
