LOCUS       gnlProkkaBBCBFNHI_61   12055 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BBCBFNHI_61.
ACCESSION   gnlProkkaBBCBFNHI_61
VERSION     gnlProkkaBBCBFNHI_61
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 03:00:40
            Original ID  :: gnl|Prokka|BBCBFNHI_61
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 8775
            Orig. end    :: 20830
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12055
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10411]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10411
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12055
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12055
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             234..1823
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 65.8;
                     E-value: 6.6e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg61_12"
                     /transl_table=11
                     /translation="MSLLYENYSEKMLKVCLRYIPDPTIAQDLLHDGFVIIFTSIHSLR
                     NPEKLEYWMKKIMRNLALQYLNHANANPTIPLTDIPEEEEPAENPFCPDFISYDKMLDI
                     VESLPEGYCKVFKLAVLEGLSHKEIGDLLGIAPHSSSSQLFRAKILLKKMLAGYRVFIV
                     LTVLLLFPTLYDYLYREKKSIRENRLSKVSSRQAGSTQQTKKTDTPRTDEQCHTKENLN
                     KRERIIPPVPVSTEWPLAIPKMKDSIHKYPIPSPFTGQTITNRQMAFASSPSLMPPTRK
                     KKSRKWKLMLAGSLGPQLAQNLYKLIATPHTDGISSDFPQQVSTWEEYYSYLHTRYQQG
                     TLGKDSIGLMQIAQNNSGRIVENQQHHAPIVVGLSLSKKLNERWSLETGLQYTLLRSEF
                     TTGEAFRIQDNQKLHYIGIPLRLSYRFWHYKRFSSYATAGMQVDIPIKGTLQSFHVTDS
                     IPHKLDSQPVSAPWQWSVNTSIGIQYHLTPQAGIYLEPTVNYYIPDGSQLRTIRKEHPF
                     TFTLPVGLRISW"
     CDS             1872..2702
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 55.5; E-value:
                     9.7e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_13"
                     /transl_table=11
                     /translation="MDNQTQEGTKNMQKRHTDRESYFDEQSQTSKNYYIPYIKEVIGHI
                     PDKVLEVGCGEGGNLLPFAKAGCRVMGVDIDAMRIEQARTFFTQRHQQGQFIATDIFQL
                     KDKATNFPLILLHDVIEHIRDKERFLSGLQKHLSADGAVFVGFPAWQMPFGGHQQIAHS
                     HIVSHFPFLHLLPRTLYRWILRLCGEQERVITELLDIKSTGCTIELFNRIVRQANYQII
                     DRRLYLINPHYKIKFGLSPRRLNGVIAAIPYIRNFFCTSCFYILKKGTKTVNHY"
     CDS             3013..3201
                     /locus_tag="ctg61_14"
                     /transl_table=11
                     /translation="MTLVHLRNINQLTSMGFVIAKTDIIVFPYYQLYRFTLREMSRTNR
                     AIHFYIYHKTKSGCYLR"
     CDS             3705..3812
                     /locus_tag="ctg61_15"
                     /transl_table=11
                     /translation="MPYPLNFHPRHEADTNYPRFDCTTLSECFGATASE"
     CDS             3763..3870
                     /locus_tag="ctg61_16"
                     /transl_table=11
                     /translation="MTAPLYRNASEQQLPSDVTSQHLVPGLSFNLLYFD"
     CDS             complement(4157..4315)
                     /locus_tag="ctg61_17"
                     /transl_table=11
                     /translation="MQISITEDRYSLLQGVIPSTDTGFGSCLNIDDNGVHIFYVWKIIV
                     FITKSQY"
     CDS             4668..6473
                     /locus_tag="ctg61_18"
                     /transl_table=11
                     /translation="MEDIFSKRKTLRTIKADTSDYFIPLFHTLAVFLSTKETIITKRFL
                     EHIMKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFNKNGVKDXXXXX
                     XXXXXXXENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLWKDGIGAIDEHLN
                     GFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNEGIRGVESYRATN
                     FPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQRWGRYEEVYGESP
                     YLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQMSPREVENIHIYP
                     FKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVVSDSDAVEYLYTK
                     HGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEEVINDRVRDILRV
                     KFLIGLFDAPYQTDLADADREVEKEENEAIALQASRESIVLLKNAGELLPLDINSTKKI
                     AVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGCDLVDAHWPESEI
                     IXXXXXXXXXXXXXXXXXXXXXXXS"
     CDS             6490..7644
                     /locus_tag="ctg61_19"
                     /transl_table=11
                     /translation="MGGGQRTCGENKSRTSLDLPGRQLQLLQAIQATGKPVVLILINGR
                     PLSINWADKFVPAILEAWYPGSKGGTALADILFGDYNPGGKLTVTFPKTVGQIPFNFPC
                     KPSSQIDGGKNPGPTGNMSRINGALYPFGYGLSYTTFEYSDLDITPRVITPNESATVRL
                     KVTNTGKRAGDEVVQLYIRDVLSSITTYEKNLAGFQRIHLEPGEAQELSFTIDRKHLEL
                     LDADMKWVVEPGDFVLMAGASSEDIRLNGTLTVEDYQTRAKAIEAQKPAKRVSASTNPE
                     DAENVLDEKINTAWQGNKGDYITFALKNGAKVDKVAIAFTRDNNLPATFEIQLSGGGGQ
                     FLTVYSGTVSEYGKLISYPFKGTTASDLRIVLNDDRVSIAEVKF"
     CDS             7746..8873
                     /locus_tag="ctg61_20"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLAFDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDDPIPHASLEAVDIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             9022..9993
                     /locus_tag="ctg61_21"
                     /transl_table=11
                     /translation="MMRGKDYGVTYMLPKTEIEIVLQATKHTYTPGEFCRYADRYLRLN
                     NVSAEPEEFWTLDKIETRIAGVPDKDNVYFVKMKDKTVAPLMELTEDGIVRSINIPFSG
                     KPAAKTPEAKATESSIDPRSFLTEEILMSNSSAKMAELVAKEIYSIRESKNALLRGEAD
                     NMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKKEPKTFTIRLTPKEMKDEVAFRFSRKL
                     GVVANNDLAGEPYYISVTDLKSPDVSATEEGKKKVDGVAYNLPGKAQVTLMYNNKKLFD
                     DQLPITQFGTVEYLAPVLFNKNSTIKVLFDTATGGLIKVDRE"
     CDS             complement(10001..10411)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_22"
                     /sec_met_domain="PqqD_RRE (E-value: 3.2e-10, bitscore:
                     30.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.6e-17, bitscore: 52.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVISWKSLIFRNNRKSGYRMMEIPEGKVSLLDAVPVRCGHITTEW
                     EGECAVLAYPRFKYEWMRRFLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLA
                     RHFGEEENYIPRVTAYVMQLRKDGFIQLTIRN"
     CDS             complement(10374..11705)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 98.8; E-value: 4.3e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg61_23"
                     /transl_table=11
                     /translation="MIVAFTMMVAYYVNDVVAPLKTMLETDLAWSSTDFGFFTGGYSFL
                     NVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYYAMTGLAGADATLFGINEIFG
                     YKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKELATAMGVQVALARIGSQAGYA
                     VAIPLARAFGISTPVLLGLVLLLGGMIAFFIFAVMDKKLDKQMEAAAIAAGTEDEEEKF
                     SFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELMIIKYGINENVAGTFAGLPAL
                     GALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAIPDINYWLVAIVLMIILGIAF
                     SLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIPTLIGWVLDAYCISGKKPDGT
                     NMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEEPNIQK"
ORIGIN
        1 attcccactc cggtggtgaa gctgcctcaa ggatttacgc tgaacagcat caactatgta
       61 ctgaaaggca tttgtccgga ctgtgcagca gaagtcaacc gggaggctta gttaaaaaat
      121 aaaaatccat gcagtcattc atgttcttct ctatccttaa gaaataacat tgagacaaac
      181 acatggatac aaaagctctt gtcactttat gccagaaggg aaacgggcag gccttgagcc
      241 tgctctacga aaactattca gagaaaatgc tgaaagtatg cctacgctat attcccgacc
      301 caacgatagc ccaagatctt cttcacgacg gttttgtcat catattcact tccattcatt
      361 cgctgcgcaa cccggagaaa ctggaatact ggatgaaaaa gattatgaga aacctggcac
      421 tgcaatacct caaccatgcc aatgccaacc ccaccatccc attgacagat attccggaag
      481 aggaagagcc tgctgaaaat cctttttgtc cggatttcat ttcgtacgat aagatgctgg
      541 atatagtgga gagccttccg gagggctact gcaaggtatt taaactggca gtactggaag
      601 gattgtccca caaagaaatc ggagatttac tgggtatagc gccacactcc tcttcctccc
      661 aattgttccg ggcgaaaatt ttacttaaaa agatgctggc aggataccgt gtattcattg
      721 ttttgacagt attgcttctc tttccaacgc tatatgacta tctgtacaga gagaaaaaga
      781 gtatcaggga aaaccgtttg tccaaagttt cttccaggca agccgggagt acgcaacaaa
      841 caaagaaaac cgatactccc cgaaccgacg aacaatgcca taccaaagaa aatctgaaca
      901 aaagggaacg aatcatccct cccgttcctg tttccacaga atggcccctt gccataccca
      961 aaatgaaaga tagcatccac aaatatccca taccttctcc attcaccgga cagaccatca
     1021 ccaaccggca gatggctttc gcctcctccc cttccctaat gccgccaacc cgcaagaaga
     1081 aatccaggaa atggaagttg atgctggcag ggtcactcgg accgcaactg gcacagaact
     1141 tatataagct gattgccact ccacataccg acggcatttc aagtgacttc cctcaacaag
     1201 tcagcacgtg ggaagagtat tattcttatc tgcacacccg ctatcagcag ggtactctgg
     1261 gaaaagattc catcggactc atgcagattg cccagaataa cagcggcagg attgttgaga
     1321 accagcaaca tcatgccccc atcgtcgtgg gactctctct cagcaagaaa ttgaatgagc
     1381 gttggagtct ggaaaccgga ttgcaatata cgcttctcag gtcggagttc actaccggcg
     1441 aagcattccg cattcaagac aaccagaagt tgcattatat cggcattcct ctccggcttt
     1501 cctaccgttt ctggcattac aaacgtttct ccagttatgc cacggcaggc atgcaggtgg
     1561 atatccccat aaaagggaca ctccaaagct tccatgtcac agacagtatt ccacacaagc
     1621 tcgacagcca gccggtaagt gctccctggc agtggtcggt caacacaagt ataggcatac
     1681 aatatcacct cacaccccag gcaggcatct atctggagcc gactgtaaac tattatatcc
     1741 ccgacggcag ccaactgcgc accatccgaa aggaacaccc gttcacattc accctcccgg
     1801 taggcctccg catttcctgg taaaaaaacg atgcgccacg cagtctttta cccgactgat
     1861 tatctattta tatggataat caaactcaag aaggaacaaa gaacatgcag aaacgacata
     1921 ccgaccggga aagctacttt gatgaacagt cacagaccag caagaactat tatatcccct
     1981 acataaagga agtcatcgga cacatccccg ataaagtgct ggaagtgggc tgtggagagg
     2041 gaggcaatct gcttcccttt gccaaagccg gttgccgggt gatgggcgta gacattgatg
     2101 ccatgcgaat agagcaagcc aggaccttct tcacccaaag gcatcagcag ggacagttca
     2161 ttgccaccga cattttccag cttaaggaca aggctacgaa ttttcccctg attcttctac
     2221 acgatgtgat agagcatatc agagacaaag aacggttcct ctccggccta caaaaacatt
     2281 tgtctgccga cggagctgta tttgtagggt ttcccgcctg gcaaatgcca ttcggaggcc
     2341 accagcagat agcacacagc cacattgttt cacatttccc ttttctccac ctccttcccc
     2401 gcactttata cagatggata ttaagactat gcggtgagca ggaacgcgta atcacggagc
     2461 tactggatat aaagagcacc ggatgcacca tcgaactgtt caatcgcatc gtccggcaag
     2521 ccaactatca aatcattgac cggagactgt accttataaa cccacattat aaaatcaaat
     2581 tcggcttgtc cccacgaagg ctcaacggag ttattgctgc tatcccgtat ataagaaact
     2641 tcttttgtac aagttgcttt tacatattaa agaaagggac taaaactgtt aatcactact
     2701 gatttcccag ctttagaatt gattccgaac catcaattta agattatata ttcagaagaa
     2761 accattaatt ttttgaatag ctctgatgaa agagtgggtg tagaaaccct cataaactaa
     2821 aaaatccccc tcgctgcaga tggttgtagc gaaggtgatt tcaataaaag aggaacttgc
     2881 acttcctccc ttttaatgtt tttacatcgt tacttggttc attacagcct cgtcaggtgt
     2941 cgttcctatt tcatcggcaa ataatatgtg ggtgatagac cctctcgggg tcggagtttc
     3001 gattttaatt ctttgacctt ggtacatctc cggaatatca accagcttac atctatgggc
     3061 ttcgttattg ccaaaactga cataatagtc tttccctatt accagcttta caggtttacg
     3121 ttgagagaaa tgagtcggac aaacagagct atccactttt atatctatca caaaaccaag
     3181 agcggatgtt accttagata gtatatcaat gctcacatta taagcccctt tctctatctt
     3241 ggctatatta acacgattaa caccacaaag attagccaat tcctcttggg tcatatttct
     3301 cttcttgcga agaatggcta accgactacc aatccgttca cgttctttca aaatcttctc
     3361 tgtacatttt ccttcgtgaa ttttcataaa tctgttgcag aatttaaagt gttgccccca
     3421 cttctaatag ttattgattt ttgaacagac aaaagtagat attaattttg aattgtagca
     3481 catttactac aactattttc taaatgaata taaaaggtag ggggagtaga agaaaagaaa
     3541 aagcccctga attactggaa ttcaaggact tacaaacttc tttttactat atccgtggag
     3601 ctggagggaa tcgaaccctc gtccaaacga ggaaatcata agctttctac atgcttatct
     3661 ttgcctaaat tttcgtgcag cggcagaacc aaagccatca accgttgcct tatcctctaa
     3721 attttcaccc gcgccacgag gctgacacga actatccccg atttgactgc accactttat
     3781 cggaatgctt cggagcaaca gcttccgagt gatgtcacgt cccagcacct ggtgccggga
     3841 ttaagcttca atctactata cttcgattaa gcagcgagag cgtaacgagt ttcgccagat
     3901 aaaattttga ggactgagat taaagtgcaa atcaacgacg cactgcatgc ttacttacca
     3961 tttctgcccg ctgtcaaatc cagtcaaccc catgactttg taacggtctg aaatttaaaa
     4021 gattgcgtaa ctcattgcta agtagggagg gtgaaaaagg gataaatgct actttatttt
     4081 tcatcctcta ccgctttctt tggcccaaag atacatattc ttttattagc aatcaccata
     4141 tatttacaaa tattagctaa tactgacttt tcgtgataaa aacaataatc ttccatacat
     4201 agaatatgtg caccccattg tcatcaatgt tcaaacagct accaaagcca gtatccgttg
     4261 acggaattac cccctgcaag agggaatatc tatcttctgt aatggatatt tgcacaaaag
     4321 agatgggaaa ttaacggaaa aagtctctga agttaactga aaaaccggaa agaattaagg
     4381 aagcaatcta tcccaaactt tggttttttc atacccagcc ttgggatgtc taaaccaagg
     4441 tttggtttag acatcccaag gttgaaaaga aagttcttcc gtacaagcaa caattccgcc
     4501 aacagattcc tattatataa atacaccctc gtttaacaga tgtagccgta atacttgtat
     4561 acaccgcgat tgcatctact tttcaggtta ttatagtgtt ctctctttct ttttaaaagt
     4621 gaatgatatg tttcgtctaa taatgatttg aattccccgg tagcgtcttg gaggatattt
     4681 ttagtaagag gaagaccctt cggacaataa aagccgatac ttcggactat tttatccctt
     4741 tatttcacac attagccgta tttttgtcaa caaaagaaac aataataacc aagagatttt
     4801 tagaacatat catgaagaac cttattgccc taaccctgct gcttggagga agcacactgc
     4861 tctgcgcaca aaagcctgcc aaaacaccgg caacctacaa gccggtgaaa agtgaaatgt
     4921 accgcaaagg ttggatagac ttcaacaaaa acggagtgaa agacgnnnnn nnnnnnnnnn
     4981 nnnnnnnnnn nnnnnnnnnc gaaaacctgc tgcaacagat gacgctggac gaaaagacct
     5041 gccaaatggt caccctctac ggttacaaac gtgtactgaa agacgacctc cccacccccg
     5101 aatggaaaga gctgctctgg aaagacggta tcggcgccat cgacgaacac ctaaacggct
     5161 tccagcaatg ggggctgcct ccctcggaca atgcctacgt ctggcccgcc tcgcgccacg
     5221 cctgggcact gaacgaggtg caacggttct ttgtggaaga tacccgtctc ggtatccccg
     5281 tagactttac caacgaaggc atacgcggcg tggaaagcta ccgcgccacc aacttcccca
     5341 cccaactggg actgggacat acctggaacc gtgaactgat tcgccaagta ggactcatca
     5401 ccggacgcga agcccgcatg ctgggctaca ccaacgtcta cgcccccatc ctcgacgtag
     5461 gacgcgacca gcgctgggga cgctacgaag aagtttacgg cgaatctccc tacctcgtag
     5521 ccgaactggg catcgaaatg gtgcgcggct tgcagcacaa ccaccaagtg gccgccaccg
     5581 gcaagcactt tgccgcttac agtaacaaca aaggcgcccg cgaaggcatg gcacgcgtgg
     5641 acccgcaaat gtcgccgcgc gaagtggaaa acatacacat ctaccccttc aaacgcgtca
     5701 tccgggaagc tggcatgctg ggcgtaatga gttcgtacaa cgattacgac ggcatccccg
     5761 tgcagggcag ctactactgg ctcaccaccc gcctgcgtgg cgaaatggga ttccgtggct
     5821 acgtcgtatc cgacagtgac gccgtagaat acctctacac caagcacggc accgccaaag
     5881 acatgaaaga agccgtccgc caaagcgtgg aagccggact gaacgtacgc tgcaccttcc
     5941 gctcgcccga ctccttcgtc cttcccctcc gcgaactggt gaaggaaggc ggactgagcg
     6001 aagaagtcat caacgaccgc gtgcgcgaca tccttcgggt aaagttcctc atcggtctgt
     6061 tcgatgcccc ctatcagaca gaccttgccg atgccgaccg tgaagtggaa aaagaagaga
     6121 acgaagccat tgccttgcag gcatcccgcg agtccatcgt tctgctgaag aatgccggtg
     6181 aactattgcc cttagacatc aactccacca agaagattgc cgtctgtggt cccaatgcca
     6241 atgaagaagg ctacgcgctg acccattacg gcccacttgc cgtagaagtg accactgtgc
     6301 tggaaggcat tcaagaaaag acaaaaggca aggcagaggt gctctacacc aaaggctgcg
     6361 acctggtgga cgcccactgg cccgaaagtg aaatcataga nnnnnnnnnn nnnnnnnnnn
     6421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnncaagc tgatgttgcc
     6481 gtcgtagtat tgggcggcgg acaacgcacc tgcggcgaaa acaaatcgcg caccagcctc
     6541 gacctgcccg gtcggcagtt gcaactgctt caagccatac aagccacggg caagcccgtc
     6601 gtactgatac tcatcaacgg acgcccgctc tccatcaact gggcagacaa gttcgtcccc
     6661 gctatcctcg aagcctggta tcccggctcc aaaggcggaa cagccctggc cgacatcctc
     6721 ttcggcgact acaaccccgg tggaaagctg acggtgacct tccccaagac cgtagggcaa
     6781 atccccttca acttcccctg caaaccttct tcacagatag acggcggtaa gaatccggga
     6841 cctacgggca acatgtcacg catcaacgga gcactctacc ccttcggcta cggcctgagc
     6901 tacaccacct tcgagtactc cgacctcgac atcacccccc gagtcatcac cccgaacgag
     6961 tctgccaccg tccgcctgaa ggtgaccaac accggcaaac gtgccggaga tgaagtagtg
     7021 cagctctata tccgcgacgt actgagcagc atcaccacct acgaaaagaa tcttgcaggc
     7081 ttccagcgca tccacctcga accgggcgaa gcccaggagc tgtccttcac catcgaccgc
     7141 aagcacctgg agcttctgga cgctgacatg aaatgggtgg tggaacccgg cgacttcgtg
     7201 ctcatggccg gcgcctcttc cgaagacatc cgcctgaacg gaacgctgac cgtagaagac
     7261 taccagaccc gtgccaaagc cattgaagcc caaaaaccag caaagcgtgt gagtgccagc
     7321 accaacccag aggatgccga aaacgtgctc gacgaaaaaa tcaataccgc atggcaagga
     7381 aataagggag attatattac ctttgcctta aagaacggag ccaaggtaga taaagttgcc
     7441 attgccttta cacgtgacaa caacctgccg gcaaccttcg aaatccagct ctcgggcggt
     7501 ggcggacagt tcctcaccgt atattcgggc accgtcagcg aatacggcaa actgatttcc
     7561 tatccgttca aaggcactac cgccagcgac ctccgcatcg tgctgaacga tgaccgcgtc
     7621 agtattgccg aagttaaatt ttaatgtgct aatgtgccaa tatgctaatg taccaatgac
     7681 catgcagcat atacagcgca gccaattagc acattagcat attggcacat taacacatta
     7741 aattaatgaa aacacttctt ttctgtatgc tcggattagg tttgacagca tgtggctctt
     7801 ctccaaaggg cactaacggt gaccaggacg aactcgccat gctaataggt acttacacga
     7861 atggctcaag caagggtatc tataccttcc gctttaatca ggagacggga acagccgttc
     7921 cgctcagttc agcggcattg cccaatccct cctacctcgt cccctcggaa gatggcgaat
     7981 ttgtctatgc cgtcagtgaa atgaacgaca gcacagcagc cctcagctcc cttgccttcg
     8041 accgggaaac gggagaactg cgcctgctga acaccgttcc caccttcggc gccgacccct
     8101 gctacgtggc caccaatggc cgggaagtgt tgactgccaa ctacagcggt ggaaccatgt
     8161 ccgtctttcc tttacagaaa gacggcactt tggctcctgc agacacgctc tttcaaggct
     8221 ctgccaccgg tcccgacgcc atacggcaag ccactcccca catccattgc acggtctttt
     8281 caccggacgg aaaatacatc tttgccaccg acttcagtgc cgaccgcatc ctgcgctttg
     8341 tgatgcaccc cgacgaccct attcctcatg cttctctgga agccgttgac attgaagcgg
     8401 attccggccc gcgccatctg acattcagcc ctaacgggaa gtttgcctat ctcatcaccg
     8461 aactgtccgg taaggtcatt gccttcagtt acgacgacgg ctgcctggaa cagatacaga
     8521 ctatcacagc cgacaccgta gccgcccgtg gaagtgcaga catccacctc agtccggatg
     8581 ggaaatacct ctacgccagc aaccgtctga aagaagacgg catcgccatc tttgccgtga
     8641 atcccgaaaa tgggaccttg gcaaaggtag gttatcagcc caccggcatc catccccgca
     8701 acttcaacat cacgcccaac ggcaaatact tgcttgccgc ctgccgcgac agcaatgtca
     8761 ttcaggtata caaacgaaac gaagttaccg gactcttgga agatactcat caggacattg
     8821 tagtcgacat gccggtttgc gtacagttcg tcagctctgt taataattta taaagcaata
     8881 tttagcaaag ataacttcat taactttgtc ccttagctaa atcagtctaa acgaatgtac
     8941 attatgaaga agaatatatt gatgctctca gctctgttct tgtctatcac tgccatggcg
     9001 caaacagacg taaccaccgg tgtgatgcgt ggcaaagact acggagtgac ttatatgttg
     9061 cccaaaacag aaatagaaat cgtattgcaa gccaccaagc atacctacac tcccggagaa
     9121 ttttgcagat atgccgaccg ctatctgcgt ctcaacaacg tgtctgccga acccgaggag
     9181 ttctggacac tggataagat agaaacccgc atagccggtg taccggataa ggacaacgtc
     9241 tatttcgtga agatgaaaga caagaccgta gcacccctta tggagcttac cgaagacgga
     9301 attgtccgct ccatcaacat tccgttcagc ggtaagcctg ctgccaagac gcccgaagcc
     9361 aaagccaccg aaagcagcat tgacccacgc agttttctga cggaagaaat actgatgtcc
     9421 aactccagtg ccaagatggc cgagctggtg gccaaggaaa tatacagcat ccgcgaaagc
     9481 aagaatgccc tcctgcgcgg cgaagcagac aatatgccca aggacggcgc ccaactcaag
     9541 ctgatgcttg acaatctgaa ccagcaggaa acggctatga cggaaatgtt ctcgggcaaa
     9601 ataaagaaag aacccaagac attcaccatc cggctgacgc ctaaagagat gaaagatgag
     9661 gtggctttcc gtttttcccg gaagctggga gtggtggcca ataatgacct tgccggtgaa
     9721 ccgtattata tcagcgtcac cgacctcaaa agtcccgatg tatctgccac cgaggaaggc
     9781 aaaaagaaag tggacggtgt agcctataac cttccgggca aggcacaagt gacattgatg
     9841 tataacaata agaaattgtt tgacgaccaa cttcccatta cccaattcgg caccgtagaa
     9901 tacctcgcac cggtactgtt caacaagaat tctaccatca aagtgctgtt tgatacggca
     9961 acgggaggat tgataaaagt agatagggaa taaaggaatt ctaattccgg attgtcaact
    10021 ggataaatcc atccttacgc aactgcatta cgtaggcggt gacccgggga atataattct
    10081 cttcctcccc aaagtgcctg gcaagtagag agatgatttc gcgcacggta cgatgtccat
    10141 ctatcagatt ccagacagct gtaccgtgtt cttccagcct cacatggatg tcaggagaca
    10201 tccccttcgg caataaaaaa cgacgcatcc attcgtattt aaaccgtggg taggcgagta
    10261 cggcgcactc accttcccat tcggttgtta tatgtccaca gcggaccgga acagcgtcca
    10321 acagacttac ttttccttcg ggtatttcca tcatacggta tccgcttttc ctattatttc
    10381 tgaatattag gctcttccag cttataacca tacttcttgt ctgccttctt cagcagtaga
    10441 gccactataa gggacaagca ggcaataccg gtaaaaatgc acataggcac cgtatagtca
    10501 tacatattcg ttccatctgg tttcttgccg gatatacaat aggcatcaag cacccaccct
    10561 atcaatgtag gaatacccca aagaccgata ttctggataa agaaaatcaa tgcgtatgcc
    10621 gtacccaact ggcttaccgg gaatatcttg gccacagccg gccacatggc agaaggtacc
    10681 agcgagaaag cgatacccaa aattatcatc agcacaatag ctaccagcca atagtttata
    10741 tcgggaatag cataaatgaa atgcacacat atcagcatgg ccgagcccag cagcatgata
    10801 gatgcggact tgccccgctt gtcaatgaaa ccaccaaaga ccggagtcag aatcagcgct
    10861 cccaatgccg gaagtccggc aaatgtaccg gccacattct cattgatacc gtatttgata
    10921 atcatcaact cggaagcaaa cttctggaat gggaatacac aagagtagaa caatacacac
    10981 agcaatgcta tcagccagaa accgggattg accagaatat tcttcacatc cttaaaagag
    11041 aacttctctt cctcatcttc cgtaccggca gcaatggcag cagcttccat ctgtttgtcc
    11101 agcttcttgt ccatcactgc aaagatgaag aaagcaatca taccgcccaa caacagaacc
    11161 aaacccaaca acaccggtgt ggaaataccg aaagcgcggg ccaaaggaat ggctacggca
    11221 taaccggctt gcgaaccgat acgtgctaaa gcgacttgta cccccatagc cgtggcaagc
    11281 tctttcccct taaaccactt ggctatgatt ttggaaactg taataccggc gacctccgct
    11341 cctactccaa aaatggaata accggcaaaa gcaacaaaca cacccgtttt atagccaaat
    11401 atttcattga ttccgaataa agtcgcgtcg gcaccggcaa gtcccgtcat tgcatagtat
    11461 tcaagtgctg taccacctac catcaggata gttgccagct ttccggtgaa acggatacca
    11521 aagcggtcga ggattaatcc tccccaaatc aacatcagga aaaaaacatt cagaaaacta
    11581 taaccaccgg taaagaatcc gaaatcggta ctcgaccaag ccaagtccgt ttccaacatt
    11641 gtcttcaacg gtgctaccac gtcgtttaca taataagcta ccatcatcgt gaaggcaaca
    11701 atcaccaatg ccccccaacg ggtagccttg gaatcattca atttaagttt gagttgttct
    11761 gtcattgtac tatttggatt tcaatttatt aatcagattg cataaattgc tgacaaaggt
    11821 aaataaatac ttcatcaaaa cgaaaaaagg ctgacacctt ttcagtatca acctttctct
    11881 tatttttcca agcgggagtc atccgcaata tccttatctt attctgctgc aggggcttct
    11941 gctgcaggag caggagtttc agccggagtt gtagctgcag gggcctccga ttgcggagct
    12001 tctgtaccta cgggcatgtt ataaggatta gttttttctt cttgttgcgc ctgtt
//
