LOCUS       c00371_gnlPro..         4898 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ALJFNDAH_371.
ACCESSION   c00371_gnlPro..
VERSION     c00371_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 16:39:46
            Original ID  :: gnl|Prokka|ALJFNDAH_371
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4898
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1584
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg371_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-47, bitscore:
                     149.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LYDHQNTLNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGAT
                     NAITGIADAMIDSTPIVVIAGQVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVA
                     WAIARAFYIASSGRPGPVVLDFAKNAQVEKTKYEPTQQEFIRSYVPVPDTDEESVKAAA
                     ELINNAERPLVLVGQGVELGSAQEELRIFIEKADMPAGCTLLGLSALPTDHPLNKGMLG
                     MHGNLGPNINTNKCDVLIAVGMRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDI
                     AVLGDCKKTLAAVTGLLKKNRHTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVR
                     AVSEATRHEAILVTDVGQNQMISARYFKYTRERSIVTSGGLGTMGFGLPAAIGATFGRP
                     DRTVCVFMGDGGLQMNIQELGTIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTP
                     MLNPDYMKIASAYDIPSKRVFSREELKAAIDEMLSTDGAFLLEACVVEEGNVLPMTPPG
                     GSVNQMLLEC"
     protocluster    1..4898
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4016]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..4016
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4898
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4898
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1603..2166
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg371_2"
                     /sec_met_domain="ALS_ss_C (E-value: 2.7e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             2166..2909
                     /locus_tag="ctg371_3"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGNELSFFCDEV
                     SENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             2973..4016
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg371_4"
                     /sec_met_domain="IlvN (E-value: 1.6e-47, bitscore: 149.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 8.8e-41, bitscore: 128.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQRQGKTYDKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGNAMDRTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYHSVKTGNEAQISIDSNSKPDYREKLEEELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(4549..4896)
                     /locus_tag="ctg371_5"
                     /transl_table=11
                     /translation="LDESIDFGLISPYKAQVQYLRSKIRGSSFLRPFRSLITVNTVDGF
                     QGQERDVVFISLVRANEDGQIGFLNDLRRMNVAITRARMKLVILGDATTLTKHAFYRKL
                     IQYIRQEAVSS"
ORIGIN
        1 ctgtacgacc atcaaaatac attgaaccat atcttggttc gccatgaaca gggagctgcc
       61 catgcggcac aaggctacgc ccgtgtatcg ggtaaagtcg gtgtttgctt ggtgacaagc
      121 ggccccggag caaccaatgc gatcacaggt attgcagatg cgatgataga cagtacgcct
      181 atcgttgtca ttgcaggaca ggtgggaaca ggctttcttg gaacagacgc ttttcaggaa
      241 gtcgatctcg taggtatcac tcagccaatc gctaaatgga gctatcagat tcgccgtgcc
      301 gaagacgtag cctgggcgat agcacgtgct ttctacattg ccagtagtgg tcgtcccggt
      361 ccggtggtac tcgactttgc caagaatgcg caggttgaaa aaacaaaata cgagccgacg
      421 cagcaggagt ttatccgcag ctatgttccg gttcccgata cagacgaaga atcagtaaag
      481 gctgccgccg aactgatcaa taacgccgaa cgcccgcttg tcttggtagg acagggagtg
      541 gaactgggaa gcgctcagga agaactgcgt atctttatcg aaaaggcgga tatgcccgca
      601 ggttgtacct tgctcggact ttccgcattg cctaccgacc atccgttgaa taaaggaatg
      661 ctgggtatgc acggaaatct gggaccgaat atcaatacta acaaatgtga tgtactgatt
      721 gctgtcggta tgcgtttcga cgaccgtgtg accggtaatc tggctactta cgccaaacaa
      781 gcgaaagtga tccattttga cattgatccg gcggaagtaa ataagaatgt aaaggtagac
      841 attgccgttt tgggcgactg caaaaagacg ctggctgctg tgaccggact gctgaaaaag
      901 aaccggcaca ccgagtgggt cgatagtttc aaggaatatg aagcggtaga ggaagaaaaa
      961 gtcattcgtc ccgaacttca tcctgcaacg gattcactga gtatgggcga agtggtgcgt
     1021 gcggtaagcg aagcgacccg tcacgaagcc atattggtga cagatgtagg tcagaatcag
     1081 atgatctctg cccgctactt taaatatacc agggaacgta gtatcgttac ttcgggtgga
     1141 cttggcacga tgggttttgg ccttccggca gctatcggag ctactttcgg ccgtcccgac
     1201 cgcactgtat gtgtatttat gggtgacggc ggactgcaaa tgaacattca ggaactgggt
     1261 acgatcatgg aacagaaagc tccggtgaag attatctgcc tgaacaacaa ttatctcggc
     1321 aacgtgcgcc aatggcaggc tatgttcttt aatcgccgtt attcatttac tccgatgctg
     1381 aatccggatt acatgaaaat cgcttccgcc tacgatattc cttccaaacg tgtcttttca
     1441 cgggaagaat tgaaagcggc catcgacgaa atgctctcga cagacggggc gttcctgctc
     1501 gaagcctgtg tggtagaaga aggcaatgtc ctcccgatga cccctccggg cggttcagtc
     1561 aatcagatgt tgctggaatg ttaatcctta atttagaaag ttatgagtga taagacatta
     1621 tatacgatta tagttcattc tgaaaatata gccggattgc tgaatcaggt gaccgctgta
     1681 tttacccgtc ggcaaataaa catcgagagt ttgaacgttt ctgcttcttc cattaaagga
     1741 gtacataaat atacgattac agcgtggact gataaggaca ctatcgaaaa ggtggtgaag
     1801 cagatcgaaa agaagattga tgtgattcag gcgcactatt ttacggaaga cgagatttat
     1861 ttccatgaga tagccttata taaggtatct actcctgctt ttcaggagac tccggaagca
     1921 tctaaagtga tccgcagata taatgcccgc attgtagagg tgaatccggt attctctatc
     1981 gtcgagaaga acggcatgag tgaagagatt acttcccttt acgaagaact tcgggctttg
     2041 aaatgtgtgc tgcaatttgt ccgttcgggc cgtgtggcta ttactaccag ctgtttcgaa
     2101 cgtgtgaatg agttcctgga cggacaggaa gcgaagtata agcaaagtaa aaaggaacag
     2161 gagtaatgag tgaagaaaat aaaataggga cttatcagtt tgtggcagag ccgtttcacg
     2221 tagattttaa cggccgcctg accatgggcg tgctggggaa tcatctgctg aattgcgcag
     2281 gttttcatgc cagcgaccgt ggatttggta ttgctacgct gaacgaggac aattacacat
     2341 gggtgctttc ccgtctggcg atcgagctgg acgagatgcc ttaccaatac gagaagttct
     2401 cggttcagac atgggtggag aatgtctatc gtctctttac cgaccgtaac tttgccgtca
     2461 ttgacaagga tggaaagaag atcggctatg cccgttccgt atgggcgatg atcaatctga
     2521 atactcgtaa gcctgccgat ctgttggcat tgcatggagg aagcatcgtc gattatatat
     2581 gcgatgaacc ctgcccgata gaaaagcctt cgcgtatcaa ggtgacaagc aatcagcctg
     2641 ttgcgacgct gacggcaaaa tacagtgata tcgatattaa cggacacgta aacagtattc
     2701 gttatatcga gcacatactt gacttgtttc cgatagaact gtatcagacg aaacgtatcc
     2761 gccggtttga aatggcgtat gtggctgaaa gttatttcgg aaatgaactc tctttcttct
     2821 gtgatgaggt gagtgaaaac gagtttcatg tagaggtgaa gaaaaacggc agcgaggtag
     2881 tatgccgttc caaagtgata tttgaataat atagagtata aaatcaatta ataacagatg
     2941 gcgcaagtca tcaaaacaaa aaaacaaaaa aaatggcaca gttgaatttt ggcggaactg
     3001 tagaaaatgt agttatccgt gatgaatttc cattggaaaa agctcgtgaa gtattgaaaa
     3061 atgaaacaat cgctgtaatc ggttatggcg tacaaggtcc cggacaggct ctgaaccttc
     3121 gtgataacgg tttcaatgta atcgttggtc aacgccaggg aaagacatat gacaaagcgg
     3181 ttgctgacgg atgggttccg ggtgaaactt tgttcggtat tgaagaagct tgcgaaaaag
     3241 gtacgatcat tatgtgcctg ttgtctgatg cagcagtaat gtctgtatgg cctactatca
     3301 agccttacct gactgcagga aaagctcttt atttctctca tggttttgct attacatgga
     3361 gtgaccgcac aggtgtagtt cctcctgcag atatcgacgt aatcatggtt gctcctaaag
     3421 gttcgggtac atccttgcgt actatgttcc ttgaaggtcg cgggttgaac tcttcatacg
     3481 ctatctatca ggatgcaaca ggcaacgcta tggacagaac aatcgcattg ggtatcggta
     3541 tcggttcagg ttatttgttc gaaacaactt tcatccgcga agctacttcc gacctgacag
     3601 gcgaacgtgg ttcattgatg ggagctatcc agggtctgtt gctggcacaa tacgaagtgt
     3661 tacgtgaaaa cggtcacact ccttccgaag cattcaacga aactgtagaa gagctgactc
     3721 agtcattgat gccgttgttt gcaaagaacg gtatggactg gatgtatgct aactgctcta
     3781 ctacagctca acgtggtgct ctcgactgga tgggcccgtt ccacgatgct atcaaaccgg
     3841 tcgttgaaaa gttgtatcac agtgtgaaga ctggtaacga agcacagatt tcaatcgact
     3901 ctaactccaa accggattat cgtgagaaac tggaagaaga actgaaagca ttgcgcgaaa
     3961 gcgaaatgtg gcagactgcc gtgacagttc gtaaacttcg tccggaaaat aattaatcag
     4021 acttatacta tataagtttt tcaaaaggcg ggaaaatcat cttttcccgc ctcttttatg
     4081 tgtatgccac tcttttgaat gacagaataa ggatgaaagt agcaaaaaag attaaaagat
     4141 actgataata taggtgaaaa agagcattta tgattacctt tacggcaaca aataaaacag
     4201 aataggcaat gaagaaactt tttacttaca gaaaatcgat acgtatgaag atgatttctt
     4261 ctttaatgaa tagtatatca gaatgttaca ttaaaagata tttaagttat tctctaccga
     4321 atggtagctg taataccatt tcaagtcctt tttatatttc gtgttccatt agtgattcgt
     4381 tgatatgatg cagaatttta ttctgtagca ggaaaaagta tgcgttaaat tgaatttaag
     4441 acagagcttt tggaacagaa tttagtggga aaataacatt gtttgttttg tttgtaaatg
     4501 ggagtcttct ttcgtgagaa agggggcttc tttttttatc ccgatgattc aggaggatac
     4561 cgcttcctgc cggatatact gtatcagttt ccggtagaac gcatgcttgg taagagtggt
     4621 tgcatctccc aaaatcacaa gtttcatccg ggcgcgggta atggctacgt tcattcgtct
     4681 taaatcattc agaaaaccga tctgtccgtc ctcgttcgcc cggacgaggc tgataaagac
     4741 gacatcccgt tcctgtccct gaaagccgtc taccgtgttg accgtgatga ggctgcggaa
     4801 agggcggaga aaactgcttc ctctgatttt acttctcagg tattgcactt gcgccttgta
     4861 gggcgaaatc agaccaaagt cgatgctctc gtccagga
//
