LOCUS       c00176_gnlPro..         7316 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OCIBECHM_176.
ACCESSION   c00176_gnlPro..
VERSION     c00176_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 10:04:33
            Original ID  :: gnl|Prokka|OCIBECHM_176
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7316
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7316
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:5521]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..5521
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
     cand_cluster    1..7316
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /kind="single"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..7316
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /region_number="1"
                     /rules="(minimum(3, [Amidohydro_1, Amidohydro_3, Arginase,
                     FGase, Urocanase]) and Lyase_aromatic and Urocanase_C)"
                     /tool="gutsmash"
     CDS             complement(2..688)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Lyase_aromatic"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg176_1"
                     /sec_met_domain="Lyase_aromatic (E-value: 1.2e-79,
                     bitscore: 257.1, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNVYYVGSEPLSFEGVERILTQNMKLELSLEVKERIQRCRDYLD
                     HKIEQQEGPLYGITTGFGSLCNKNISPDELSTLQENLVKSHACSVGDEVSPVIVRLMML
                     LKAHALSLGHSGVQVITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLIGVG
                     DVYYKGRKREAISVLDEFALKPVKLKSKEGLALLNGTQFMSANGVFALMRAFSLSKKAD
                     LIAALSL"
     CDS             complement(692..1315)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTCD_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg176_2"
                     /sec_met_domain="FTCD_C (E-value: 7.9e-67, bitscore: 213.6,
                     seeds: 242, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLADLTIKDFLAETAGSAPVPGGGSISALNGAIAAALTEMVAHLT
                     VGKKKYAEVEGQMKTIAIEAALIRERLTEYIDKDSEAYDRVFSAFKLPKETPDEQVIRT
                     NAIQSATKEAAIVPMRVAEEIGSVMETIIYVAHKGNQNAVTDACVAMMAARTCVLGALL
                     NVRINLTSIQDEVFVGKMRKKADELEANAIRVEQKLLDWVKTKL"
     CDS             complement(1351..2601)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Amidohydro_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg176_3"
                     /sec_met_domain="Amidohydro_1 (E-value: 3e-25, bitscore:
                     78.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENSKILIRNAAQIVTCHGDKARRGAEMSDLGVIEDGAVAMSDGV
                     ITHVGPTEEVLRNIHAEDYLEIRAENQAVLPGFVDSHTHFIFGGYREEEFSWRLRGDSY
                     MSIMERGGGIVNTMKATRESDFDTLWDRGEERLDELFSMGVTTVEGKSGYGLDLQTELV
                     QLRVMSDLNESHPMDVVSTFLGAHAVPPEFAGRTDDYVDYMIEEVLPAIRAEHTVTFCD
                     VFCEKGVFSLEQSERLLRAARHHRFKLKMHADEIVPFGGAELAASLKCVSADHLLHISD
                     TGIKRLARAGVVATLLPLTAFSLNEPYAPARKMIDAGCAVALASDLNPGSCFSASIPMM
                     IALACIYMKMSPEEAVTALTINGAAAVGRASEIGSISVGKRADVILLKYPSYKFLPYHV
                     GMNLVDTVIKDGELYMM"
     CDS             complement(2605..3510)
                     /locus_tag="ctg176_4"
                     /transl_table=11
                     /translation="MSTWNKIMECVPNFSEGRDLEKIDKIVAPFRAKTGVKLLDYSNDE
                     DHNRLVVTVVGEPVALKQAVLEAIGVAVELIDLNKHSGQHPRMGAVDVVPFIPIRGCTM
                     EEAIALSKEVGEEVGAHYAVPVFLYEKSASVPYRENLAAIRKGEFEGMAEKIHQPEWKP
                     DFGPAERHPTAGTVAIGARMPLVAYNVNLGTNQLQIATDIAKKIRFIGGGLRYCKAMGV
                     ELKERGIVQVSINMTDYTRTALYRAFELVRIEARRYGVPVVGSEIIGLVPMEALIDTAS
                     YYLGLEDFSMNQVLEARIME"
     CDS             complement(3507..4769)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg176_5"
                     /sec_met_domain="Urocanase (E-value: 3.3e-63, bitscore:
                     202.2, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 6.7e-86, bitscore:
                     275.8, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGAQPKAAVIAGAASIIAEVDASRIETRRCQGWVQYVTDDMGKA
                     FSLADEAIRKKEPISIAFHGNIVDLLEYADKQGLSIDLLSDQTSCHAVYEGGYCPVGVT
                     FEERTELLAHHREDFCALVDKTLKRHFEVIKRLVARGTYFFDYGNSFMKAIYDAGIHEI
                     SRNGVDEKDGFIWPSYVEDIMGPELFDYGYGPFRWVCLSGKPEDLIRTDHAAMACIDPT
                     RRGQDMDNYNWIRDAEKNRLVVGTQARILYQDAEGRLKIALEFNRMVRDGEVGPIMLGR
                     DHHDVSGTDSPFRETSNIRDGSNVMADMAVQCFAGNAARGMSLVALHNGGGVGIGKAIN
                     GGFGMVLDGSERVDEILRSAMIWDVMGGVARRSWARNPNAMRTSATFNENRGEQYHITL
                     PYIPERAFIHEIVQTSLNKKV"
     CDS             complement(4775..5521)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg176_6"
                     /sec_met_domain="Urocanase (E-value: 8.6e-12, bitscore:
                     34.2, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 7.4e-57, bitscore:
                     179.7, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIHLDNYLPEYPSFVSGIRRAPDRGYSLTPAQTETALMNALRYI
                     PVELHEKLAPEFMEELLTRGRIYGYRYRPQGDLKAKPISEYKGKCIEGKAFQVMIDNNL
                     CFDIALYPYELVTYGETGQVCQNWMQYRLIKKYLEELTEEQTLVIESGHPLGLFHSKPD
                     APRVIITNSMMVGMFDNQKDWHIAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNA
                     GRKKLGIPQDKDLRGYLFVSSGXXXX"
     CDS             complement(5757..6791)
                     /locus_tag="ctg176_7"
                     /transl_table=11
                     /translation="MTIETEILQVLHYHPLSNRGAIASMLVNAPSDSTMKRLLADAVSK
                     GLIEVYGKGPATKYSLTPQAQVTMPLDIDTYFKNEMDDRTVQENFNFELIKQILPKVSL
                     FTEEECKRLDKAQSTFRTHLEELSETDYKKEMERLGVDLSWKSSQIEGNTYSLLETERL
                     LKERQEATGKTREEAIMLLNHKDALDFVLNVPDYLKEISVHRIEDIHSLLTKDLGVERN
                     IRCRRVGITGTNYRPLDNEFQIREALEDSCKLINGKDNIFEKSLLALVLLSYIQAFSDG
                     NKRTARITSNAILIANGYCPISFRTVDSIDYKKAMLIFYEQNNIAAFKKIFIEQFEFAV
                     KTYF"
     CDS             complement(7135..7314)
                     /locus_tag="ctg176_8"
                     /transl_table=11
                     /translation="SRPLWKPMHKQPVYKDCPAYVNGVSESLFKVGLCLPSGPYVTDRD
                     IEYIVGGIRGLIER"
ORIGIN
        1 ccaaagataa agcggcgatc agatccgctt tcttggacag gctaaacgca cgcatcaagg
       61 cgaatacgcc attggcgctc ataaattgcg taccgttcaa taaagctaac ccctccttgc
      121 ttttcagctt cacaggcttc aaagcgaact cgtccaatac gctgatcgct tcccgtttgc
      181 ggcccttata ataaacgtca cccacgccga tcagaggcag gaacaaattc gccagaggcg
      241 ccaaatcacc ggaagcacct aaagagccac gatcatacac gatcggaagc acgtcattat
      301 tgaaaaaatc cagaatacgt tgtacggtga tcacctgtac gccactatgc cccaacgaaa
      361 gggcatgcgc tttcaataac atcatcaaac ggacgatcac cggacttacc tcatccccta
      421 cgctacaggc atgacttttc accaagttct cttgcaaggt gctcaattcg tccggagaga
      481 tattcttatt acataaggaa ccgaaaccgg tagtaatccc atacaaaggc ccctcctgct
      541 gctcgatttt atgatccaag taatcccggc aacgctggat gcgctccttc acctcgagtg
      601 aaagctccaa cttcatattt tgagtaagta tccgttcgac tccctcaaaa gagagaggct
      661 cggaacccac ataatagaca ttgctcatat gctataattt agtcttcacc caatccaata
      721 acttttgctc tacacggata gcgttcgcct ccagttcatc cgctttcttc cgcatctttc
      781 cgacgaacac ctcgtcttgg atggacgtta agttaattcg gacattcaat aaagccccca
      841 atacacaagt acgggcagcc atcatcgcca cgcaagcatc cgtgacggca ttctgattac
      901 ctttgtgagc cacatagata atcgtctcca ttacggaacc gatctcctcc gccaccctca
      961 tcggaacaat agccgcctct ttagtagcgc tctgtatcgc attcgtacgg atcacctgtt
     1021 cgtcaggcgt ttctttcggc aacttaaaag ctgagaatac acgatcataa gcctcgctgt
     1081 ccttatcaat atattcagta agacgctcac ggatcaaagc cgcctcgata gcgatcgttt
     1141 tcatttgtcc ttccacttcc gcatatttct ttttgccaac agtcagatgg gccaccatct
     1201 ctgtcaaagc tgccgctata gcgccattca aggcagatat acttccacca ccgggaacgg
     1261 gagcactacc cgccgtttcc gccaaaaaat ctttaattgt caagtctgct aacatagtat
     1321 tttgatttaa atgattcaac aattcttatc ttacatcata taaagttccc cgtccttaat
     1381 tacggtatcc acgagattca ttcccacatg ataaggtaga aacttataag acgggtattt
     1441 cagcaagatc acgtccgcac gttttcccac gctgatactt ccaatctcgg aggcacgtcc
     1501 cacagctgcg gctccattaa tggtcaatgc cgttaccgct tcttcagggc tcatcttcat
     1561 atagatacag gccaaggcta tcatcatcgg gatcgaggcc gaaaaacaac ttcccggatt
     1621 tagatcggaa gctaaagcca ccgcgcaacc ggcatctatc attttccggg caggcgcata
     1681 cggctcattc aaggaaaagg cagtcagcgg aagtaaggta gctacgacac ccgctcttgc
     1741 cagacgtttg atgcctgtat ccgatatatg taataaatga tcagcactta cacacttcaa
     1801 ggaggccgcc agttccgccc ctccgaaagg aacgatctca tccgcatgca tcttcaattt
     1861 aaaacgatga tgacgggcgg cacgaagcaa gcgctcactc tgttctaacg agaaaacgcc
     1921 tttctcacaa aacacatcac aaaacgtaac cgtatgttcg gctcgtatgg caggaagaac
     1981 ttcctcgatc atataatcca cataatcgtc cgtacgaccg gcaaattcag gaggaacagc
     2041 atgagctccc aaaaaggtcg atacgacatc catcggatga gactcattca ggtccgacat
     2101 gacacgaagc tgaactaatt ctgtttgcaa atccaaacca taaccacttt tcccctccac
     2161 cgtggtaaca cccatggaga ataactcatc caaacgttct tcccctctgt cccatagtgt
     2221 atcgaaatca ctttcacggg tagctttcat cgtattcacg atacctccac cacgctccat
     2281 gatcgacata taactatctc cccgcaatcg ccaagagaac tcctcctccc ggtaaccgcc
     2341 aaagataaaa tgcgtatggc tatctacaaa tccgggtaac accgcttggt tctccgcccg
     2401 aatctccaaa taatcctccg catggatgtt tcgaagtacc tcctccgtag gtcctacatg
     2461 cgtaataacc ccatcagaca tcgctacggc tccatcctcg ataacgccta aatcagacat
     2521 ctccgctccc cgtcgtgcct tatccccatg acaagtgacg atctgggcag cattcctgat
     2581 taatatcttg ctattctcca tacgctattc cataatacgg gcttccaata cttgattcat
     2641 agagaagtcc tctaatccca aatagtaaga ggccgtatcg atcaacgcct ccataggaac
     2701 caagccgata atctcgctcc ccaccaccgg aacaccatat ctgcgagctt cgatacgaac
     2761 taactcgaag gcccggtaca aggccgtacg ggtataatcg gtcatattaa tagagacctg
     2821 tacgatacca cgttccttca actcaacccc catcgcttta caatagcgta aacctccgcc
     2881 gatgaaacgg attttcttcg ctatatccgt agcgatctgc aattgattcg ttcctaagtt
     2941 cacattatag gcgaccaaag gcatgcgggc tcctatggcg accgtaccgg ctgtcggatg
     3001 tctttcggcc ggaccaaaat caggtttcca ctccggttga tggattttct ctgccatccc
     3061 ttcaaactct cctttacgga tcgcagccag attctcccgg taagggacgg aagccgattt
     3121 ctcatataag aagaccggca cggcataatg agcgcccact tcctccccta cttccttaga
     3181 caaggcgatc gcctcttcca tcgtacatcc gcgaatcggt ataaaaggaa caacatctac
     3241 ggcccccatt cgaggatgtt gaccgctatg cttgtttaaa tcgatcaact caacggcaac
     3301 tccaatggcc tccaatacgg cttgttttaa agcgactggc tcccctacca cggtaacaac
     3361 caagcgatta tgatcctcgt cattactata gtccaacagt ttaacacccg tcttagcccg
     3421 gaaaggcgct acgatcttat ctatcttctc cagatcccgt ccttcactga agttagggac
     3481 acattccata atcttattcc aagtactcat acctttttat ttaatgatgt ttgtacgatt
     3541 tcatgaataa acgccctctc cgggatatac ggaagggtaa tatgatactg ttcgccacgg
     3601 ttctcattga aagtagcgct cgtacgcatc gcattcgggt tacgggccca tgagcgacga
     3661 gcgacacccc ccatcacgtc ccatatcata gcagagcgaa gtatctcgtc cacccgctca
     3721 ctaccatcga gaaccatacc gaaacctccg tttatcgcct taccgatacc aactcctcca
     3781 ccattatgaa gagcgaccaa gctcataccc cgggcggcat ttccagcgaa gcactgcacc
     3841 gccatatcag ccatcacatt gcttccgtcc cgtatattag aggtctcacg gaatggagaa
     3901 tccgtaccgc tcacgtcatg atggtctcgt cccaacataa tcgggcctac ctccccatca
     3961 cgtaccattc ggttaaactc aagggcgatc ttcaagcgcc cctcagcgtc ttgatataag
     4021 atccgggctt gcgtacccac caccaaacgg ttcttctccg cgtcacgtat ccaattataa
     4081 ttatccatat cctgccctct tcgagtcgga tcgatacacg ccatagccgc atgatccgtg
     4141 cgaatcaaat cttccggctt accgcttaaa catacccagc ggaaagggcc atacccataa
     4201 tcaaataatt ccggccccat gatatcttcc acataagaag gccatataaa accatctttc
     4261 tcgtccacac cgttacggga aatctcatgt ataccggcat catagatcgc tttcatgaag
     4321 gagttcccat agtcaaagaa ataggtaccc cgggcaacca gacgcttgat cacctcgaaa
     4381 tgtcgcttca acgttttatc gaccaaagca caaaagtctt cccggtgatg agccaataat
     4441 tccgtacgtt cctcaaacgt cacgcctacc gggcaataac caccttcata gaccgcatga
     4501 cacgaggtct gatcactcaa aaggtcgatg gaaagcccct gtttatcggc atattccaat
     4561 aaatccacga tattgccatg aaaagcgata gagatcggtt ctttcttacg aatcgcctcg
     4621 tcggctaagg agaaagcttt ccccatatca tccgtcacat actggaccca tccttggcat
     4681 cggcgtgtct cgatacggga agcgtctacc tcggcgatta tactggcagc accggcaatc
     4741 acggcggctt taggttgagc gccactcatt cctcctannn nnnnnnnaaa ccggaagata
     4801 caaacagata gcctcgcaaa tccttatctt gtggaatccc taatttctta cgtccagcat
     4861 tcaacaatgt attaaacgta ccgtgtacga taccttgcgg gccgatatac atccaacctc
     4921 cggccgtcat ctgtccataa ttagcgactc ccatctgggc ggcgatatgc caatcctttt
     4981 ggttatcgaa cattcccacc atcatggagt tcgtgataat cacccgtggg gcatccggct
     5041 tagaatgaaa caatcccaga ggatgcccag attcaatcac caaggtctgc tcctcggtca
     5101 gctcctccaa atacttctta atcaaacgat attgcatcca attctggcag acctgcccag
     5161 tctcgccata cgtaaccaac tcgtaagggt acaaagcgat atcaaagcag aggttattat
     5221 cgatcattac ttgaaaggcc tttccctcga tacatttacc tttatattca gagataggct
     5281 tcgctttcag gtctccctgc ggacggtagc gataaccata gatccgtccc cgggtcaata
     5341 attcctccat gaactcagga gctagcttct catgtaattc aacagggatg taacgaagcg
     5401 cgttcatcaa tgccgtttct gtttgagcgg gcgtaagcga atagccgcga tcgggagcac
     5461 ggcgaatacc ggaaacgaag gaaggatatt ccggcaaata gttatcaaga tgtatttcca
     5521 taacgtgaat gatttagtag gtgcttacaa tctgcaagga atttcacgga ttcagcgccg
     5581 acaagttagc gattatccaa atcccaacca attatcattc catgtttaga agcataaaaa
     5641 agcccccgtc tctctcatcc accctaaggg aaagaaagac gggggcataa ttataattgt
     5701 tcagtagtag aagttgtttc gtaaatacaa tagtccgtta gttttcacaa aagaaatcaa
     5761 aaataagttt tgacagcaaa ttcaaattgt tctatgaata tcttcttgaa agcggcaatg
     5821 ttattctgtt catagaatat cagcatggct tttttgtagt ctatggaatc aaccgttctg
     5881 aatgagattg ggcaataacc attggctatc agtatggcat tgcttgtgat acgggcagta
     5941 cgtttgtttc catccgaaaa tgcctgaata taagaaagga gaaccagtgc aagtaatgac
     6001 ttctcaaaga tattgtcttt gccattgata agtttacagg aatcttccaa tgcctcacga
     6061 atctggaact cgttatcaag gggacgatag ttcgtacctg tgatacccac acgtcggcat
     6121 cgtatgtttc tttccacacc taagtccttg gtcagtaaag aatggatgtc ctctatgcgg
     6181 tggacggata tttccttaag atagtcgggc acattgagaa caaaatcaag cgcatctttg
     6241 tgattgagca gcatgatagc ttcttccctt gtcttaccag tagcttcctg tctttctttc
     6301 agcaggcgct ccgtttctag cagggaataa gtattgccct cgatttgtga agatttccac
     6361 gacaggtcaa ctcccagtct ttccatctcc tttttgtaat ctgtttcaga aagttcttca
     6421 aggtgggttc tgaaagtgga ctgagcttta tccaaacgtt tacattcctc ttctgtgaaa
     6481 agtgaaacct ttggcagaat ctgttttatg agttcgaaat tgaaattttc ctgcacagta
     6541 cgatcatcca tttcattctt gaaataggta tcaatatcca aaggcatcgt tacctgagct
     6601 tgtggagtaa gcgagtattt ggtagcaggt ccttttccat acacttctat aagacctttg
     6661 ctgacagcat cagccaagag tcttttcatg gtgctgtcgc ttggtgcatt taccagcatg
     6721 gaagctatcg ctcctctatt tgatagcgga tgatagtgca atacctgtag gatttctgtt
     6781 tcgatagtca taacattcct ttcactaaat cggctcaaaa gtactaattt tccttcaact
     6841 atcggctcaa attgagccga tagtcgtatc tttaccgcaa tatttgagcc gatttgcaat
     6901 attttcccaa tacccaatgc gtaggaacac gatcctagct ctctcacaca tggtcataaa
     6961 ctccgctctc gaatagagta agactttggg gcgaaggaaa agttcagcta aagaacacaa
     7021 aaaaaggtgc atcaaaatga cacaccctcc tcgtaacaaa aataaaatct ttatgattag
     7081 cctttactta ggcctacgca ttgaaacgaa tttagctcat gaaagctgtt aaaatcaacg
     7141 ctcaatcaag ccccttatac ctccaacgat atactcaata tcccgatccg tcacatacgg
     7201 gccggaaggc aggcacaacc caaccttaaa caaagattcg ctcaccccat tcacataagc
     7261 cgggcaatcc ttataaacag gttgcttatg catcggtttc cacaaaggac gggatt
//
