LOCUS       c00095_gnlPro..        16385 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JGCIKFAG_95.
ACCESSION   c00095_gnlPro..
VERSION     c00095_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 16:58:22
            Original ID  :: gnl|Prokka|JGCIKFAG_95
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16385
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..849)
                     /locus_tag="ctg95_1"
                     /transl_table=11
                     /translation="MGADIVIATPGRLLSHLKLGTVDLSQVSYFVLDEADRMLDMGFYD
                     DIMQVYKQLPPTCQTIMFSATMPPKIRTLAKTILKNPEEVKIAISRPPETIMQTAYICY
                     DPQKLKILEDLFLQSRPQRVIIFSSSKMKVKELASTLKRMKFNVAAMHSDLEQSQREEV
                     MKEFKNGHIDILVATDVVSRGIDINDIKLVINYDIPHDPEDYVHRIGRTARGTGGEGLA
                     ITFISIEEQAQFKRIEDFLEKEVYKIPIDPKFGETPLYEPEKYGNMRRGRGRPRKDGNN
                     GG"
     protocluster    1..16385
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5637:8962]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5638..8962
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..16385
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16385
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(798..1220)
                     /locus_tag="ctg95_2"
                     /transl_table=11
                     /translation="MRFDELDLEEAVLDGLDAMNFQDTTPVQELTIPVILEGKDIIACA
                     QTGTGKTAAYVLPLINQLSKGNHPDNAVNAVIMAXXXXXXXXXXXXXXXXXXXXXXXXX
                     WPYTVVPTELPGSNRSVVWKWGPILLSPLRDVCCPT"
     CDS             1404..2546
                     /locus_tag="ctg95_3"
                     /transl_table=11
                     /translation="MGTDDSCNSSQKKVTLNEPDTVHELLNTILDHLPLGVFVKDPEDH
                     FNYLYWNKFMEEITGIDTSQIEGHDDSEVYYNALMSVEERLEVDKKVISSGKVAEFHGW
                     LKDASGAMKYLEVEKYPISLSNGKPLLLALWRDATVKRAIEKRLEDERDKAEMADKLKS
                     KYLADMSHEIRTPLNAITGFSEMMAFADTDEERMSYYEIIKANNQLLMQLINDILDLSK
                     IEADAIKISYAPIDLNEMMDTTYASVKPRMPKDVKLILEKGLDSCTFGTDYIRLLQLVN
                     NLVNNAIKNTKKGSITMGYKALEDDRLNFYVKDTGQGIAEEQLQNLFNRFVKVNDYVEG
                     IGLGLAICKGLVTKMGGSIRVESQLGEGSTFSFILPSREE"
     CDS             complement(2557..3375)
                     /locus_tag="ctg95_4"
                     /transl_table=11
                     /translation="MKSRKLLVVYIVLLACVLIAMFRLWPYKQEPVPPKDYPEIKSEGI
                     LRLVTEYNQSGYYVAGDTIEGFQYELSQAIAALSGLEVQTQLEMSLAESFKQLSDNQCD
                     VIARNIPITSDIKEDYLFTDPIVFNKQVLVQRTEEANNGIKPIRNQLDLAQKTLYIPKN
                     SPALLRLQNLAHEIGDTIYVKEDELYSSEQLAIMVAKGDIDYAVCDQQIARVSKGNLPE
                     IDIDTDISFTQLQSWAVRKDSPILLDSLNSWLSQIKESGLYDQIYKRYYK"
     CDS             complement(3381..5516)
                     /locus_tag="ctg95_5"
                     /transl_table=11
                     /translation="MKHCLYILLLLIVSATTVQAQRGASRADQKGGGKRGGFSLSNLTS
                     SQKDIPDSLLVADSAALNSKRITAYRLTPSLGEAYVAPLDTNKLNFSNSTLVESKSLAI
                     GYLANLGAPAQTKIFSERQEARDFIFADAYDYYITTPENAYFYNTKIPYTNVLYTTAGG
                     STNKEEQLKGTMTMNFGKKINVGADIDYIYGRGHYKNNGNKLLSYRFFGSYQTDRYEMH
                     AYLSNFNFVNYENGGMANDSTISHPDEYFPEGRPSDTKSYDIRYLTNAWNRVRGKRYFL
                     TQRYNLGFTRELEEEDEEGNPKEMFVPVSSIIHTIDYEDNRRRFIADNTALMDSSYIVD
                     DNGLRFPRIYGLGATLNDQTSSWNLKNTIGLSLREGFQDWVKFGLTAFVRLEKRRFKLE
                     PRIEGLDYGEYGRGPYFSVDNIDLKNLPTAKLYDEFSTYVGAELSKRQGSILTYNARGE
                     LCMVGSDVGEFRVTGDLQTRFKLFNKDAVIKADAYIKNVTPAFYMRHNHSRYYWWDNPN
                     FNMTQQIYAGGEVYLESSKTTLKAGVESIQNYIYFNKQGFPVQHGSNLQVVSARIKQDF
                     RFRAFGWENEACWQLSSDESVLPLPSLSAYSNMYLAVKVAKVLTVQLGANVYYNTAYYA
                     PYYEPATQQFQVQDEVKVGNYPLVNAYVNFHLKQARFFVMAYNLSSKFADPNYFSLAHY
                     PLNPMVLKMGIAVTFNN"
     CDS             complement(5638..6180)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_6"
                     /sec_met_domain="POR (E-value: 3.7e-37, bitscore: 118.2,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQEIIIAGFGGQGVLSMGKILAYSGLMEGKEVSWMPSYGPEQRG
                     GTANVTVILSDDPISSPILNEYDIAIILNQPSMDKFESKVKPGGILIYDGYGIHTPVKR
                     TDISVYRVDAMDAATEMKNEKAFNMLILGGLLKIVPMVKLENVLLGLKKSLPERHHKLI
                     PMNEAAIKKGMEIIQKV"
     CDS             complement(6231..6584)
                     /locus_tag="ctg95_7"
                     /transl_table=11
                     /translation="MPINTGNIILDKSFVFAIAIINYCEILEQNRKFVVSHQLLKSGTS
                     IGANINEAQNCESRADFIHKFKIAAKEAEETKYWLLLCQQAENYPFEEKLLNDLSDILR
                     LTNSIINSAKKSM"
     CDS             complement(6611..7375)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-24, bitscore:
                     76.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNEIIKPENLVYTKPGLMNDNPMHYCPGCSHGVIHKLIAEVIA
                     EMGMEEKTIGVSPVGCAVFAYNYLDIDWEEAAHGRAPAIATAIKRLNPEKMVFTYQGDG
                     DLAAIGTAETIHAANRGENIVIVFVNNAIYGMTGGQMAPTTLEGMPTATCPYGRNIALN
                     GYPLKIGDLLAQLEGTCLVTRQSVQTAAAVRKAKKMLRKAFENSMAGKGTSVVEFVSTC
                     SSGWKMTPEKANKWMEENMFPFYPLGDLKNVE"
     CDS             complement(7648..8727)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_9"
                     /sec_met_domain="PFOR_II (E-value: 4.2e-29, bitscore: 91.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 9.4e-48, bitscore: 153.0,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEIKLMKGNEAIAHAAIRYGADGYFGYPITPQSEILETLMAEM
                     PWETTGMVVLQAESEVAAINMVYGGAGTGKRVLTSSSSPGVSLKQEGVSYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLITLAPSSVQEMADFVGLGFDLAFK
                     YCNPAIILADGIIGQMMEKVVMPPFRPRKTEAEIIAECPWAAQGKLKNRKANVITSLEL
                     DPAKMEENNLRFQAKYRKIEENEVRYEEFHCDDAEYLLVAFGSSARICQKVVEIARAEG
                     IKLGLLRPITLWPFPKKAIADYAEKVKGMLSVELNAGQMVEDIRLAVNGKVKVEHFGRL
                     GGIVFTPDEVLNALKEKLF"
     CDS             complement(8735..8962)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_10"
                     /sec_met_domain="Fer4_7 (E-value: 2.3e-14, bitscore: 44.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 7.8e-08, bitscore: 22.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.4e-08, bitscore: 24.7,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.4e-07, bitscore: 19.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAVVVNQERCKGCNLCVVACPSDVLELHPREVNNKGYHYV
                     YMKNPDACIGCASCGLVCPDGCLTIYKVKI"
     CDS             complement(9102..10469)
                     /locus_tag="ctg95_11"
                     /transl_table=11
                     /translation="MKAKIVVADDEPRIRKMIARLLADEGYDVMPVENGREAVEALLSF
                     QPDVILLDQQMPVLTGVEALEEIRRISPTQVVLFVTAFGSISLAVDAVKKGAYDFIEKP
                     FDNDKLLLTVKRAVEHSRMKGEISTLKKTLGEKRSNVIGENTGLKQVMAQVLRVAETNA
                     TVLIHGESGTGKELIARAVHHNSLRANGPFVAINCGAIPLTLMESELFGHERGAFTDAK
                     EAKAGTFERANGGTLFLDEVGELPLDAQVKLLRVLEERKITRIGGKKAIPVDVRIVAAT
                     NRNLDDEVKDGHFRLDLLYRLNVFTLILPPLRERKEDIPLLANFFIRKYNQALSLDVQS
                     ITPEAVKLLSSYDWPGNVRDLENALQSAMILCTDGTIRPEHLPDRVKGYDSTEEATIAG
                     SGGSIREINAQMEKELILEALKKHNFNRTLTAEALAISRKTLFNKMKRYGLSTDEI"
     CDS             complement(10466..11710)
                     /locus_tag="ctg95_12"
                     /transl_table=11
                     /translation="MPLFKKDEQPRQPNLEQLLSEFNRSLTLIVDKSLLIGNIVAKVKQ
                     ICPVESVYIFLLDENTGKFKLQNEAKNKPVTLTNRSRLVSWLSVNEKHLIISRHPDIVS
                     YFPPEEQEIIRQLGAELIFPLKIMNQINGTIFLGKKTDGAPFTEQELNLLSILINQATF
                     AIEHASLYEQQTERLKKMYRTDRLATLGELAAGAAHEIRNPLTAIRSTIQYLSKDFSTD
                     PVKSEMVTELISEVERINKIVQGLLSFARPSDLNTSDINIEQLINQTLLLVTNTLRKQN
                     VEVEFEYFTDNTTIQGDAEQLKQVFLNIILNAVEAMGKNPPERSRTLIISIEKGTPINT
                     HSRYLIISFEDSGKGIEQKNIENVFNPFFTTKEEGTGLGLAICYGIINRHEGEIEVKSV
                     PDKGTCMNIKLPQRI"
     CDS             complement(11751..12863)
                     /locus_tag="ctg95_13"
                     /transl_table=11
                     /translation="MFKHTGWTSKGPAGLEYSGIMEGSHETALMVAAYQKGIRKDGEAI
                     YEAVLKNVTETGIGHPCGGSCGNPLLDIYIKQGYMPMEKGVVSKTLDYAYDDWCVSQLA
                     LALGKKKEGKALLARSMNYKNVFHPEKKFVMRRDSLGNWDPDFDVFSNKGFIEGNSWQY
                     SWYVPHDIPGLVDFLGKDLFNSRLEEGFIKSEKHKFAAHVFDRTTGQSAEFYINQGNEV
                     NMCTPFLFNYSGKPWLAQKWSRAILDSFYGSTPYHGWEGDEDEGQMGGWYVMSALGLFE
                     MNGGVSLKPELELTSPLFNKITIRLDPGYYKGKTFTIKARNNSKENIYIQKAYLNGKEL
                     KQPRIPFVAIVSGGTLLLEMGDKPKFDCFN"
     CDS             complement(12878..14056)
                     /locus_tag="ctg95_14"
                     /transl_table=11
                     /translation="MNSRQISSYILILLSLPFTLISAKPKEPVDYVDMFIGTSNSRWML
                     GPYAQEPFGMVQLGPDNQGNVWMGGYEYAINSVSGFSHLHAWTMGGLMIMPTTADLALT
                     NPSADSPYKGANAGYHSRILKETEKASPGYYSVYLYDHEVKAELSATTRCGIHRYTFPE
                     RKESRILIDLLFPTEWDYSFNVKDACITKVSNTELEGYANCQSGPWSNWNNYKLHFVIR
                     FSKPFSQLNGWNEGVEKDDIRSIAGKNDIGAYAIYSTTEGESITVSTGLSLVSIEQARL
                     NMDTELAPLQYDFDRVVAQTRNKWNELLGRIEIEGTNEVDKTKFYTNLYRAYAGKQTWN
                     DVNGQYRDACENIQQLDHGNMYGGDAFWNSFWNLNXXXXXXXSSPPASWTIG"
     CDS             14357..15874
                     /locus_tag="ctg95_15"
                     /transl_table=11
                     /translation="MKRNLLVSLLMGFALAGHAETENLRQITYDEAIHIALGESYTVKY
                     YKEDMDATRYSYLYTKAQFKPLLNFDFFTPSWTESLTEISQADGLPVYNSTGSLQVGGN
                     LNFTYVLPTGGNFALSSKMYWENYRTTLSQRDYEELERDQVYSRFALSFNQPIFTANKL
                     KENMKVAELDYKKSTCYFTRIQMDIVYNVTESFYTVYKLAYEHKINQDRLVNSREAYRI
                     TKLKQETGNLPEGEMLIAEITVAQDEARVMESEGKLAAAKDQFKLLIGLDLKEEIDLKA
                     DMEFEAFIVDMQLAIDEALRNRMEIKEDNLDIELQAIEVKRAKREREFKGNISAYYDFT
                     GLSTRGDGTVGQLVGSSFDNMRDRPANRGIALTVSYPLLDWGRAKNQVRREQVRLKQRE
                     LNLDNTKRTIEQEIREIVRSVYEAEKRYRINRRNQEVAIQSYRISQMRFENGDMTSQEL
                     SIEQERLSQVQLAYIDSYITYRLSVADLNRKTMYDFEHNRSFLPEKG"
     CDS             16083..16385
                     /locus_tag="ctg95_16"
                     /transl_table=11
                     /translation="MNKHMKSFIAVLLAILLMPFTVRAQEDSEAALLLDLKKTRADYEV
                     AKQKYENDTKLYNEKAISANDFNRSKNELLSKEVDYQKLILKLISQQSYITVERAV"
ORIGIN
        1 tcctccgtta ttaccatctt tccggggacg tccgcgtccg cggcgcatgt ttccgtactt
       61 ttcaggttcg tatagcgggg tttcgccgaa cttcgggtcg ataggaatct tataaacttc
      121 tttttccagg aagtcttcaa tacgtttgaa ttgtgcctgc tcttcaatgc tgatgaatgt
      181 gatggctaat ccttcgcctc cggtaccacg ggcggtacgg ccgatgcggt gtacgtaatc
      241 ttccgggtcg tgggggatat cgtagttaat caccagtttg atgtcgttga tgtcgatacc
      301 gcgcgaaaca acatcggttg ccaccagtat atcgatatgt ccgttcttga attctttcat
      361 tacttcctcg cgctgcgact gctccaggtc ggagtgcatg gcagctacat tgaacttcat
      421 ccgtttcagg gtggaggcaa gttctttcac tttcattttg gaggaagaga aaataatgac
      481 acgctgcggg cggctttgca ggaacaggtc ttcgagtatc tttagcttct gaggatcata
      541 gcagatatag gccgtctgca taattgtttc gggaggacgt gagatggcta ttttgacttc
      601 ttcgggattc ttcaggattg tttttgctaa cgtccggatt ttgggaggca tggtagccga
      661 gaacatgata gtctgacaag taggaggcag ttgtttgtat acctgcatga tgtcgtcgta
      721 aaatcccata tccagcatac ggtctgcttc atccagtaca aaataggaaa cctgtgaaag
      781 gtctaccgtt cccagtttca ggtgggacaa caaacgtccc ggagtggcga taacaatatc
      841 ggcccccatt tccataccac gcttctgttg ctcccaggca actccgtcgg taccaccgta
      901 tacggccann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      961 nnnnnnnnnn nnnnnnnnnn nnnngccatg ataactgcat tgaccgcatt gtcaggatga
     1021 ttgcctttac ttaattgatt aattaatggc agcacgtagg ctgctgtttt ccctgtaccg
     1081 gtttgtgcgc aggcaataat atccttccct tctaaaataa caggaatcgt taattcctgt
     1141 acaggagttg tatcctgaaa attcatagca tcgagtccgt ccaatacggc ctcttctaaa
     1201 tccaattcgt caaatctcat cttctatcat taaattctcc gtaaaggtaa ataatatttg
     1261 tcaaattcta caatagtaac accggctctt gtaacaattg tcctgtaaat ttctgtaagc
     1321 gttgaaaatt gatatatcta tatagtgggg taacataaaa aattaatatc tttgcccaca
     1381 ttggaaaaat agcgagttat attatgggaa cagatgatag ctgtaacagc tctcaaaaga
     1441 aagtaacctt aaatgagccg gatactgttc atgagttact gaatacgata ttagatcatt
     1501 tgccactggg tgtatttgta aaagatccgg aagatcattt caattatctt tactggaata
     1561 aatttatgga agagataacg gggatcgata cttcccagat cgagggacat gatgactctg
     1621 aagtgtatta taatgccttg atgtcggtag aggaacgact ggaggtagat aagaaggtca
     1681 tcagttcggg aaaggtggcc gaatttcacg gctggctcaa ggatgcttcc ggcgcgatga
     1741 aatatcttga agtagaaaag tatccgattt ctttaagcaa tggaaaacct ttgttgttgg
     1801 ctttgtggcg tgatgccact gttaagcggg caatagaaaa acgtctcgaa gatgagcgtg
     1861 ataaggcgga aatggctgat aagttgaaat caaaatatct ggcagacatg agtcatgaga
     1921 tccgtacgcc gttgaatgca ataaccggtt tttcagaaat gatggcgttt gcggatacgg
     1981 acgaggagcg tatgtcttat tacgagatca tcaaggcgaa taatcaattg cttatgcagc
     2041 ttatcaacga tattctggac ttgtcgaaga ttgaggcgga tgcgataaag attagttatg
     2101 ctccgatcga cctgaacgag atgatggata cgacctatgc ttccgtaaag ccccgtatgc
     2161 cgaaagatgt gaagttgatt ctggaaaaag gattggacag ctgtaccttt ggaaccgatt
     2221 atatccgctt actccaatta gtcaataacc tggtcaataa tgcgatcaag aatactaaaa
     2281 agggaagtat tacgatgggg tataaggcgc tggaagatga ccggctgaat ttctatgtga
     2341 aggataccgg acaggggata gccgaggagc agctacaaaa cctctttaac cgctttgtta
     2401 aagtcaatga ctatgtggaa ggtattggcc tgggacttgc tatatgcaaa ggacttgtta
     2461 ctaaaatggg aggctcgatc cgtgtagaat cgcaactagg ggaaggttcc actttttcgt
     2521 ttatcctgcc ttcacgggaa gaatgaggat atacttttat ttatagtagc gtttgtaaat
     2581 ctgatcgtat aacccgcttt ctttgatttg tgacagccag ctgttcaggc tgtcgagcag
     2641 gataggggag tctttgcgta ccgcccacga ctggagttgg gtgaaactga tatccgtgtc
     2701 gatatctatt tccggtaaat tccctttaga tacgcgggct atttgctggt cgcatacggc
     2761 atagtcgatg tcgcctttgg caaccataat agccagctgt tcgctggaat aaagttcatc
     2821 ttctttcaca tagattgtat ctcctatttc gtgtgccaga ttttgcaggc gcagtaaggc
     2881 gggggagttt ttcggaatat acaaggtctt ttgcgccagg tcgagttgat tacggatcgg
     2941 tttgatgccg ttattggctt cttccgtgcg ttgcaccagt acttgtttat tgaagacgat
     3001 cggatcggtg aacagatagt cctctttgat gtcgctggtg ataggaatat tgcgggcgat
     3061 tacgtcgcat tggttatcgg ataattgttt gaaactttcg gccaggctca tctccagctg
     3121 agtctgtact tccagtccgg ataaagcggc gatggcctgg ctcagttcgt attggaaacc
     3181 ttcgatcgta tcgccggcta cataatagcc ggactggtta tattcggtaa ccagtcgcag
     3241 aataccttct gacttaattt ccggataatc cttgggtggg acaggttcct gcttgtacgg
     3301 ccataaacgg aacatggcta tcagtacgca tgccaagagg acaatataga ctaccagtaa
     3361 cttccgggat ttcatacggc ttagttattg aatgtaacgg caatacccat tttcaacacc
     3421 atcggattca acggatagtg tgccagggag aaatagttcg gatcagcaaa cttactgctc
     3481 aggttgtaag ccatcacaaa gaaccgggcc tgtttcaggt ggaagtttac gtaggcgtta
     3541 accagtggat aattaccgac ttttacttca tcctgaacct ggaactgctg tgttgccggt
     3601 tcgtagtaag gtgcataata agctgtatta taatatacat tggcacctag ctgtacggtc
     3661 agtactttcg ccaccttgac ggccagatac atatttgaat aggcacttaa tgacggaagc
     3721 gggagtacgc tttcatcgct gcttaactgc cagcatgctt cattttccca gccgaaagca
     3781 cggaagcgga agtcttgttt gatgcgtgca ctgactacct gtaagttgct gccatgctgt
     3841 accgggaatc cctgtttatt gaaatagata taattctgaa tactttccac tccggctttc
     3901 aaagtagtct ttgaagattc cagatacact tcaccgcccg catagatttg ctgcgtcatg
     3961 ttaaagttgg ggttatccca ccagtaataa cgggaatggt tatggcgcat gtaaaaggcc
     4021 ggcgttacat tctttatata ggcgtctgct ttgatcacag catctttatt gaacaacttg
     4081 aaacgggttt gcaaatcccc ggtaacacgg aactcaccga cgtcgctacc taccatacaa
     4141 agttctccgc gtgcattata ggtcaggatg ctaccctggc gtttggaaag ttcggctcca
     4201 acgtaagtag aaaactcgtc gtaaagcttt gccgtaggca ggttcttcag gtcgatatta
     4261 tcaacagaga agtatggacc ccggccatat tcgccataat cgagcccttc tattctgggt
     4321 tccagtttga accggcgttt ttcgagtctg acgaaagctg tcaaaccaaa cttaacccag
     4381 tcctggaaac cttcacgcag ggaaagtccg atcgtatttt tcagattcca tgaagatgtc
     4441 tggtcgttga gtgtagctcc tagtccataa atacgtggga aacgcaggcc gttgtcgtcg
     4501 actatatagg acgaatccat cagcgccgta ttgtcggcga tgaaccggcg acggttatct
     4561 tcataatcga tcgtatggat aatgctggat accgggacga acatttcttt gggattccct
     4621 tcttcatcct cttcctccaa ctcacgtgtg aaaccgaggt tataacgctg ggtcaggaaa
     4681 taccgtttcc cgcgaacacg gttccaggca ttggtcagat aacgtatgtc gtacgatttt
     4741 gtatcggagg gacgtccttc cgggaaatac tcgtcgggat gactgatggt tgagtcgttt
     4801 gccattcctc cgttttcgta atttacgaag ttgaagttac tcaggtaggc atgcatttcg
     4861 taccggtcgg tctggtaact gccgaagaaa cggtagctta acagtttatt accgttgttt
     4921 ttataatgtc cgcggccata aatatagtcg atatcggcac ccacattgat ctttttaccg
     4981 aaattcatgg tcatggttcc tttcaactgt tcttctttgt tcgtactacc gccggcggtg
     5041 gtgtacagaa cgttggtata aggaatcttt gtgttgtaga aataagcgtt ttccggcgtt
     5101 gtgatatagt aatcgtaggc atcggcgaag ataaaatcgc gtgcttcctg ccgttcggag
     5161 aatattttcg tctgtgccgg tgctcccagg ttagccaggt aaccgatggc gagcgattta
     5221 ctttccacca gtgtcgagtt gctgaaattc agcttgttcg tatccagtgg cgccacatat
     5281 gcctcaccca gggaaggggt aagccgatag gcggttatac gctttgaatt taaggcggca
     5341 ctgtccgcta ccagcagact gtccggtata tctttctgag aagaagtcag gtttgacaag
     5401 gagaagccgc cacgttttcc tccacctttc tgatctgccc tgctggctcc acgttgggcc
     5461 tgaacggttg tggcagatac tatcagcaat aataatatgt ataagcaatg cttcatgggt
     5521 tgcaaagata atataatgtg ctaataaatc aatgtgccaa tatgccaata aaccttatac
     5581 aacctctggt ctattgttta attggcatat tagcacattc tttatattgg catattatta
     5641 taccttctgt ataatttcca tccccttctt aatggcggct tcgttcatcg ggattaactt
     5701 gtggtgacgt tcgggcaggg acttcttcag acccagcaat acgttttcaa gtttcaccat
     5761 cggaacgatc ttcagcagac cacccaggat aagcatattg aatgcttttt cgttcttcat
     5821 ttcggtagct gcgtccatag catccacacg ataaacgctg atatccgtac gtttcaccgg
     5881 agtatgaatt ccatatccgt catagatcag gataccaccc ggttttactt tgctttcgaa
     5941 cttgtccatg gaaggctggt tcaggatgat cgcaatatcg tattcgttca gaatcggaga
     6001 actgataggg tcgtcgctca ggataacggt cacgttagcc gtaccaccac gctgttcagg
     6061 cccgtatgaa ggcatccagc taacctcttt gccttccatc agtccggaat aagcaagtat
     6121 cttacccatc gacagaacac cttgtccacc aaagcctgct ataattattt cttgtttcat
     6181 tgtaataatt tgctaatatg ccaatatgcc aatgtgccaa taactaaaga ctacattgat
     6241 tttttggctg aattaataat actgttagtc aatctcaata tatcggaaag atcatttaat
     6301 aacttctctt caaaaggata attttctgct tgctggcata atagcagcca atatttggtc
     6361 tcttcggcct cctttgctgc tattttaaac ttatgaataa agtcagcacg actttcgcaa
     6421 ttttgagctt cattaatatt tgctccaata gatgtaccgc tttttaataa ttgatgggat
     6481 acaacaaact ttctgttttg ctctaatatt tcgcaataat taattatagc aatagcaaaa
     6541 acaaaacttt tatcaagaat aatattccct gtattaattg gcatattggc acattatcta
     6601 tattggcaca ttattcaacg ttttttagat cacccagcgg atagaacggg aacatgtttt
     6661 cctccatcca tttgtttgct ttttcaggtg tcatcttcca gccggatgaa caggtggaaa
     6721 cgaattcgac aactgacgtg cctttgcctg ccatagagtt ttcgaaggct ttgcgaagca
     6781 tcttcttggc tttacgaacg gcagcggctg tctgtacgct ctggcgggta accaggcagg
     6841 ttccttccag ctgagccagc agatcaccga tcttcaatgg gtaaccgttc agggcgatgt
     6901 tacgtccgta cgggcaagtg gctgtcggca taccttccag tgtggtagga gccatctgtc
     6961 cgccggtcat accgtagatg gcattgttca cgaatacgat cacaatgttc tcaccgcggt
     7021 tggcagcatg gatggtctcg gctgtaccga tagcggccag gtcgccgtca ccctgatagg
     7081 tgaagaccat cttttccgga ttcagacgtt tgatggctgt tgcaatcgcc ggagcacgtc
     7141 cgtgagctgc ttcttcccag tctatatcca gatagttata tgcgaaaacg gcgcaaccca
     7201 ccggggagac accgattgtt ttttcttcca ttcccatttc ggcgatcact tcggcgatca
     7261 gcttatgtat cacaccgtgg ctgcaaccgg gacagtagtg catgggattg tcgttcatca
     7321 atcccggttt tgtatagacc agattctccg gtttaattat ttcgttgagt tccataaaaa
     7381 taatttttca atgtggcaat atgccaatgt gccaatgaaa gtccaattct tataattggc
     7441 atatcggcat attgtctgat tggcatatta tttaactaat aaatctcagt agatattgaa
     7501 caagtctgaa gcatatggct gctccgccgc aatagagaaa tacgtgacgg tcgtcaacgg
     7561 caaagtagca gatgatcgct gccgccgcca ataccatgaa caggattgtc aatatgctat
     7621 ctattttact tccgcgtgtc atacgaatca gaataatttc tctttcagcg cgttcagtac
     7681 ttcatccgga gtgaacacga taccacccag gcggccgaag tgttcaacct ttacttttcc
     7741 gtttacagcc aggcggatat cttccaccat ctggccggca ttcagttcga cggaaagcat
     7801 gccttttacc ttttcggcat aatcggcaat ggcttttttc gggaacggcc acagcgtgat
     7861 cgggcgcaac aggccgagtt tgataccttc ggcacgtgcg atctccacaa ctttctgaca
     7921 aatacgtgcg gaagaaccga aggcaaccag cagatattcc gcatcgtcgc aatggaactc
     7981 ttcgtagcgt acttcgtttt cttcaatctt acgatattta gcctggaagc ggaggttgtt
     8041 ctcttccatt ttggccgggt cgagctccag tgaagtgatc acgttcgctt tgcggttttt
     8101 cagtttgcct tgcgcagccc acggacattc ggcgatgatc tcagcttctg tcttacgcgg
     8161 acggaaagga ggcatcacca ctttttccat catctggccg atgataccgt cggcaaggat
     8221 aatagccgga ttgcaatatt tgaaggcaag gtcgaaaccc agtccgacaa agtctgccat
     8281 ctcctgtacg gaagaagggg ccagggtaat caggcgatag tcgccgtgtc cgccaccttt
     8341 cacagtctgg aagtagtcag cctggctcgg ctggattgtt cccaggccgg gaccgccacg
     8401 catgacgttt acaatcagac aaggaagttc cgcacctgca atataggaaa caccttcctg
     8461 tttcaggctg acgccggggc tggaagatga agtcaataca cgtttacctg ttccggcacc
     8521 gccatacacc atattgatcg ctgccacttc gctttcagct tgcagtacta ccataccggt
     8581 agtttcccag ggcatttcag ccatcagggt ttccaggatc tccgattgcg gagtgatagg
     8641 gtatccgaag tatccgtcgg caccgtagcg gatagctgcg tgggcgatgg cttcgttccc
     8701 cttcattaat tttatctctt ctgccatatc tgttttatat ttttactttg tagatggtta
     8761 aacagccgtc gggacaaacc aatccgcaac tggcgcaacc gatgcaagca tccgggtttt
     8821 tcatgtacac ataatggtac cctttgttgt tcacttcacg cgggtgtaat tccagaacat
     8881 cgctggggca ggcaactaca cataagttgc accctttgca gcgttcctgg tttacaacga
     8941 ccgctccttt tatctttgcc atagtataac taattatgtt ttatgtcgtg taggtcggca
     9001 aagttaagaa ctaatgttgt aaaaacaagg attgtttagt tttttaatag tcgttagcct
     9061 ctaatgatga cagatagcca atgaatagta atggctgtct gtcaaatttc atctgtagac
     9121 agtccgtaac gcttcatttt gttaaacaac gttttccggc tgatagcaag agcctcggct
     9181 gtcagtgtac ggttgaagtt gtgcttcttt aaggcttcca gaatcagttc cttttccatt
     9241 tgcgcattga tttcgcggat gcttcctccg cttccggcga tggttgcttc ttccgtcgaa
     9301 tcatatcctt ttacccggtc gggcaaatgt tcggggcgga tcgtaccgtc cgtacataag
     9361 atcatggcac tttgcagggc attctccagg tcacgcacat tgccgggcca gtcgtaggag
     9421 gagagtagct ttaccgcttc gggagtgata gactgcacat cgaggctcaa tgcctggttg
     9481 tatttacgga taaagaaatt agccagcagg ggaatatctt ctttcctttc cctgagcggg
     9541 ggaaggatca gggtaaatac attcagacga tacaacaggt cgagacggaa atgtccgtct
     9601 tttacttcat cgtccagatt acggttggtg gcggctacga tacgcacatc taccggtatc
     9661 gccttctttc cgccgattcg ggtgatcttc cgctcttcca gcacacggag caatttaacc
     9721 tgtgcatcca ggggaagttc tcccacttcg tcgagaaaca atgtaccgcc gtttgcccgt
     9781 tcgaaagtgc ctgcctttgc ttctttggca tcggtaaagg caccgcgttc atggccgaat
     9841 agttcgcttt ccatcaatgt caggggaatg gcaccgcagt tgatggcaac gaaagggccg
     9901 ttcgcccgca ggctgttgtg gtggacggca cgggcgatca gttcttttcc cgtaccgctc
     9961 tcgccgtgga tcaggacggt cgcattggtt tccgctaccc gcaggacctg tgccatcact
    10021 tgtttcaacc ctgtgttctc gccgatcacg ttgcttcgtt tttcccccag tgtctttttc
    10081 agggtggaga tttcaccttt catgcggctg tgttcgacgg cacgtttgac ggtgagtaat
    10141 aatttatcgt tgtcgaaagg cttttctata aagtcgtaag cccctttctt cacagcgtcg
    10201 acggcgaggg agatggaacc gaaggcggtc acaaaaagga caacctgggt cggagagata
    10261 cgcctgatct cctccaatgc ttccacaccg gtcagtaccg gcatctgctg gtccagcaga
    10321 ataacgtcgg gctggaagga gaggagagcc tctaccgcct cccgtccgtt ttcgacgggc
    10381 attacatcat atccttcatc ggccagcaaa cgggcgatca tcttgcggat gcgcggctcg
    10441 tcgtcggcta ctactatttt tgctttcata tgcgttgcgg taattttata ttcatacaag
    10501 tgcccttgtc cggcacgctt tttacttcga tctcgccttc atggcggttg atgataccgt
    10561 agcagatggc gagcccgagt ccggttcctt cttccttggt cgtgaagaag gggttgaata
    10621 cattctcgat gttcttctgt tcgatcccct tgccgctatc ctcgaacgaa atgatcaggt
    10681 aacgggaatg ggtattgatg ggagttccct tttctatact tattattaat gtacgcgagc
    10741 gttccggcgg attcttcccc atcgcttcga cggcattcag gatgatattc aggaaaacct
    10801 gtttcagctg ttccgcatcc ccctgaatgg tcgtattgtc ggtgaagtat tcgaattcca
    10861 cctctacgtt ttgtttacgt aatgtgttgg taaccagcag aagcgtctgg ttgatcagtt
    10921 gttcgatatt tatatcggac gtgttcaggt cggacggacg ggcgaaagac aacagacctt
    10981 gtacgatctt gttgatacgt tccacttccg agatcagctc cgtcaccatt tcgcttttca
    11041 ctgggtcggt gctgaagtct ttgctcagat attgtatcgt gctccggatg gctgtcagcg
    11101 ggttacgtat ctcatgggcc gccccggctg ccagttcgcc gagtgttgcc aggcggtcgg
    11161 tacggtacat ctttttcaga cgttcggtct gctgctcgta aagcgaagca tgttcgatgg
    11221 cgaatgtagc ctggttgatc aggatggaaa gcaggttcag ttcctgttcg gtgaatgggg
    11281 cgccatcggt tttcttccct aaaaagatcg taccgttgat ctggttcatg atcttgagag
    11341 gaaagatcag ttcggcaccc agttgcctga ttatttcctg ttcttcggga ggaaaatagg
    11401 agactatatc cggatgcctg gagatgatca gatgcttttc gttgacggac agccagctga
    11461 ccagccggct gcggttggtc agcgtcacag gcttgttctt cgcttcgttc tgcagtttga
    11521 atttgcctgt gttttcatcc agcaggaaga tataaacact ttctaccggg catatttgct
    11581 ttaccttggc aacgatattg ccgatcagca atgacttgtc gacgatcaga gtgagcgacc
    11641 ggttaaactc cgagagcagc tgctccaggt tcggttgcct gggttgttcg tccttcttga
    11701 atagtggcat actttttctt gatctttgtg caaaagtacg caaaatcgta ttaattgaaa
    11761 caatcgaact tcggtttatc tcccatctcg agcaacaacg tccctccgga tacgatggct
    11821 acgaatggta ttcggggttg tttcagttct tttccgttca ggtaagcctt ttggatatag
    11881 atgttttctt ttgagttgtt gcgggctttg atcgtgaaag tcttcccttt ataataaccg
    11941 gggtccagac ggatcgttat tttgttgaat agcgggctgg tcagttccag ttccggtttc
    12001 agagaaactc ctccgttcat ttcgaacagc cccagtgcac tcatcacgta ccaaccgccc
    12061 atctgccctt catcctcgtc gccttcccaa ccatgataag gggttgagcc gtagaaactg
    12121 tccaggatgg cacgcgacca tttctgggcc agccagggtt taccggaata gttgaacagg
    12181 aacggggtac acatatttac ttcgtttccc tgattgatgt aaaactcagc cgactgtcct
    12241 gtggtacggt cgaatacatg ggcggcaaac ttatgctttt ccgatttgat aaatccctct
    12301 tccagccggc tgttgaagag gtctttcccc aggaagtcta ccagtccggg aatatcgtgc
    12361 ggcacgtacc aggagtattg ccagctgtta ccttctatga atcccttatt ggagaacaca
    12421 tcgaaatccg ggtcccagtt acccaggctg tcacgccgca tgacgaactt tttctccggg
    12481 tggaatacgt tcttataatt catggaacgt gccagcagcg cttttccttc ttttttcttt
    12541 ccgagtgcca aggccagttg ggagacgcac cagtcgtcgt acgcataatc gagcgttttg
    12601 gaaaccactc ccttttccat cggcatatat ccttgtttga tataaatgtc cagcagaggg
    12661 ttgccgcagc tgcctccgca gggatggccg atacctgttt ccgtgacgtt tttcagcacg
    12721 gcttcataga tcgcttcacc gtctttgcgt atgccttttt gataggcggc aaccatcagg
    12781 gctgtttcgt gcgaaccttc catgatgccg gagtattcca gtccggccgg ccctttgctt
    12841 gtccatccgg tatgtttgaa catttccagc tgggtggtta cccaatcgtc cacgatgcgg
    12901 ggggagatga tcnnnnnnnn nnnnnnnnnn ngtttagatt ccagaaactg ttccagaagg
    12961 catcgccgcc atacatattc ccgtgatcca gttgttgtat gttttcacaa gcgtctctat
    13021 attggccgtt cacatcgttc catgtttgtt tgccggcata ggcacggtac aggttggtgt
    13081 agaattttgt tttgtccacc tcgttcgttc cttctatttc tatcctgccg agcagttcgt
    13141 tccatttgtt gcgggtctgg gcgactaccc ggtcgaagtc atactgcaag ggggcgagtt
    13201 ccgtgtccat attcagccgt gcctgttcga tacttaccag cgataaaccg gttgagacgg
    13261 ttatgctttc tccttcggtt gtggaataga ttgcgtaggc tccgatatcg ttcttgccgg
    13321 caatggatcg tatgtcgtct ttttctactc cttcgttcca tccgttcagt tgcgagaaag
    13381 gtttgctgaa acggatgacg aaatgcagtt tgtagttgtt ccagttactc cacggaccgg
    13441 actggcagtt ggcatatcct tcgagttcgg tgttgctgac tttggtgatg caggcatctt
    13501 tcacattgaa gctgtagtcc cattcggtcg ggaataggag gtctatcagt atcctggatt
    13561 cttttctttc gggaaaagtg taccggtgaa tgccgcaacg ggtggtggcc gatagttccg
    13621 cttttacctc atgatcgtat aaatagacgg aatagtaacc gggtgaggcc ttttccgttt
    13681 ctttcagtat gcgtgaatga taaccggcgt ttgctccttt atagggagaa tcggccgaag
    13741 ggtttgtcag ggccaggtcg gctgtggtcg gcatgatcat caggccaccc atcgtccagg
    13801 catgcagatg gctgaaaccg gaaacgctgt tgatggcgta ttcgtatcct cccatccaga
    13861 cattcccctg gttatccggt ccgagttgca ccatgccgaa cggttcttgt gcataaggtc
    13921 ccagcatcca ccgggagttg gaagtaccga taaacatatc cacataatcg acgggttctt
    13981 tcggttttgc cgaaatgagg gtgaaaggga gagacaggag aattaagatg taactgctta
    14041 tttgtctgct attcatggtg ttgatctatt aattattgta aggcaaagat atgtgttttc
    14101 ttttgtgcgg gtatataact ttctgctgat tcggttgcat tatcttatga tggcgtgcaa
    14161 ttgggtaaaa tattacccac tttgggtaac ggctttccct tttacccaag ggggaaataa
    14221 ttacccatcc gggtaaccgg tggaaataca accggttgcg gttttggcac gccatttgcc
    14281 ttactatagg caggtaaaac aataaataat gacaattggg taacctgtta cccgaaagaa
    14341 cttaattcga tatagtatga aaagaaattt actggtatca ctgttgatgg gattcgcttt
    14401 ggcagggcat gcggagacgg agaatctccg gcagatcacc tatgatgaag cgattcacat
    14461 tgctttgggg gaaagctata cggtgaaata ttacaaggaa gatatggacg caacccgtta
    14521 ctcttacctt tacacaaaag cacaattcaa gccgttgctg aactttgact tctttactcc
    14581 ttcatggacg gaaagcctga cggagatttc gcaggccgac ggtctgccgg tctacaactc
    14641 taccggttcg ttacaagtgg gcggcaacct gaactttacg tatgtcttgc ctaccggcgg
    14701 taatttcgcc ctgagctcca agatgtactg ggagaattac cggactacac tttcgcagcg
    14761 ggattatgaa gagctggaac gcgaccaggt gtacagccgt tttgccctct ctttcaatca
    14821 acccatcttt accgccaata aactgaagga aaacatgaaa gtggccgaac tcgattataa
    14881 gaagagtacc tgctatttca cccgtatcca gatggatatc gtctataatg taacggagag
    14941 tttctatact gtatataaac tggcctacga acataaaatc aatcaggacc gccttgtcaa
    15001 ctcccgtgaa gcctaccgta tcaccaaatt gaaacaggag acgggcaacc ttcccgaagg
    15061 tgaaatgctg atcgccgaga ttaccgtcgc acaagacgaa gcccgtgtga tggaaagcga
    15121 aggcaagctc gccgccgcca aagaccagtt caagctactt atcggccttg acctcaaaga
    15181 agagatcgac ctgaaagcgg atatggagtt cgaagccttc atcgtcgaca tgcaactggc
    15241 catcgacgag gctttgcgta accgcatgga aataaaggaa gacaaccttg atatcgaact
    15301 tcaggccatc gaagtgaagc gtgccaaacg ggaacgggaa tttaaaggaa acatttccgc
    15361 ctattatgat ttcaccggat tgagtacacg cggagatgga acagtcggtc aactggtcgg
    15421 ctcatcgttc gataacatgc gcgaccgtcc ggctaaccgg ggtatcgccc tgaccgtctc
    15481 ttatccgctt ctggactggg gacgtgccaa aaaccaggta cgccgcgagc aagtccgcct
    15541 gaaacagcgc gaattgaatc tcgacaatac caagcggact atcgaacagg agattcgcga
    15601 gatcgtccgt agcgtgtatg aagcggagaa gcgttaccgc atcaaccgcc ggaaccagga
    15661 agtggcgata cagagttacc gtatcagcca gatgcgtttt gagaacggcg atatgacgag
    15721 ccaggaactt tctatcgaac aggagcgcct ttcgcaggtg cagcttgcct atatcgacag
    15781 ttatatcacc tatcgtctct cggtagccga cctgaaccgg aagaccatgt atgacttcga
    15841 acataaccgc agttttctgc cggagaaagg atagaaacca gatttgctta gtattctggt
    15901 tcatagcaga ttgcagtttc attgctgttc ctgcttgtga aacaaaagtt tctcctgcat
    15961 gaaactttag tttcttcggt acaaaacttt agtttcctcc tgacaaaact aaagttttca
    16021 tagcaggaaa ctgaaatgcc ttcgggagca aattagaatg ataacataat aaataagaac
    16081 agatgaacaa acacatgaaa agttttattg cggtattgct ggccatcctt ctgatgccct
    16141 ttaccgtccg ggcacaggaa gacagcgagg ctgccttgtt gctcgacctg aaaaagaccc
    16201 gtgccgatta cgaagtggcc aaacagaagt atgagaacga cacgaagctg tataatgaaa
    16261 aagccatttc agccaacgat ttcaaccgtt cgaagaatga gttgctgagt aaggaagtcg
    16321 attatcagaa actgatcctg aagctgatct cccagcagag ttacataacg gtggaacgtg
    16381 cggtg
//
