LOCUS       c00011_gnlPro..        22906 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NLAFOLGP_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 12:38:45
            Original ID  :: gnl|Prokka|NLAFOLGP_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22906
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..246
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 60.5; E-value:
                     3.7e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_1"
                     /sec_met_domain="Biotin_lipoyl (E-value: 6.8e-19, bitscore:
                     60.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="PAPAPAPAAAGAGDVPSPLAGKVVSLDVAAGTPVKAGDQILTLEA
                     MKMNTIIYAPASGTLTAFCVNPGDTVQEGQALAKIG"
     protocluster    1..22906
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2867:12906]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2868..12906
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..22906
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22906
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             325..1989
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_2"
                     /sec_met_domain="OAD_beta (E-value: 1.4e-158, bitscore:
                     520.3, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLFDSLITFLQGMGVFSLSWQMVGMWGIAILLLYLGVAKQYEPL
                     LMVPIAFGALIANIPDNGMLITQLNQQVISSNEQGEVTATSLNNVGYLRVHVAPLQQAP
                     SKVPANLTTPESRSQYQEIMQQPMQVYPGSQLTVSKIKSVRESQEKAKADAARLGDDSL
                     TVDPNLKDFQNVTEDNGNEPVFLLTNGEGTTVVRQQGVNYFDTSGNRIPVDLKTQKLEP
                     LVVSAAGKYVAVGQHTQELLVTSIHGGLYDWIGLGIKAEIFPPIIFLGVGALTDFGPLL
                     AAPRTLLLGAAAQVGVAATFFMALFMGFTPNESASIGIIGGADGPTSIFLTMKLAPHLL
                     GAVAVAAYTYMSLVPLIQPPIMALLTTKKERLIRMKSLRTVSKSEKLFFAVLVTIVTIL
                     LIPDASPLIGMLMLGNFLRECKVTERLVQASQNEIINIVTIFLGTSVGLTMQGDRFLQS
                     ETLLIILLGIVAFGVATAGGVIAAKIMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVG
                     QKYDPSNYLLMHAMGPNVAGVIGTAVIAGYYIATLAK"
     CDS             2027..2806
                     /locus_tag="ctg11_3"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARALPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPEDTAAGVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVSSIAGEIKDPPAR
                     LADLVRDCPSLHAVMASLGSHLNQVLSVFSHGGVPALQEGLSRAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGTVRTIPAHLINRLLEE"
     CDS             2868..4364
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_4"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 6.5e-46,
                     bitscore: 148.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 4.6e-43,
                     bitscore: 140.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGALGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERAQTIIENCVHPDYKNILWD
                     YLKLSDGKAQTPQSIRAALGMHAELARSGDMKNVDWAQYK"
     CDS             4484..5185
                     /locus_tag="ctg11_5"
                     /transl_table=11
                     /translation="MNWMIYPAARAFIKVCSVLFGTGAAAAVLIHLFMPFFLRSPRTAA
                     PFLLLGTGAELLSILSLSFLMFWGVRVLLASRGSRITRNLSMLAFLPALYALLIPFAGM
                     PVPSQYTEMDRVWEAVLLLSAVTSFFSFPYTAGYGAAGRRLFLAWGIAAAGCGLQSALF
                     FLAVLLRQFLSTAVPSLAAPVAWLAVLLSCGLEIMLAALSAILAQRLFKEVMSIASMPE
                     PIDPSMPGNRP"
     CDS             complement(5389..6252)
                     /locus_tag="ctg11_6"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPVTLSVSKQLLPVYDKPMVYYPISVLMLAG
                     IREILVISTPRDLPLYRDLLGDGSRFGVSFKYREQPRPEGLAQAFIIGEEFIGKDSVAL
                     VLGDNIFYGRGLTEKLRRAAELTSGATIFGYQVHDPQRFGVVEFNEEGKAVSIEEKPPR
                     PKSDIAVTGLYFYDNRVVEIAKRIPKSSRGELEITSVNQEYLKQGLLRVEKLARGYTWL
                     DTGTHDTLLEASMFVRTLEHHQGFKVACLEEIAFNNGWISQETLRSQAGAMNNNGYGRY
                     LDELVK"
     CDS             complement(6262..7314)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 2.1e-98, bitscore:
                     322.6, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIVTGGAGFIGSNLVRLLLERGHEVLNIDALTYAGNIHSLDGS
                     ADSPAYRFLHADVRDASLMRRTLREYAPDWVMHLAAESHVDRSIDDPGNFMTTNVMGTF
                     SMLQAALEYYRSLEGEKKERFRFHHISTDEVYGSLGKEGLFTESTPYRPHSPYSASKAS
                     SDHLVRAWHDTYGLPVLITNCSNNYGPYQFPEKLIPVVILKALGGEPIPVYGKGENVRD
                     WLYVGDHCEALLTVVSCGKPGETYNIGGNNEKTNLELVELLCSHLDELRPRPDGRSYRE
                     QISFVQDRPGHDLRYAIDASKIRRELGWTPRQDHSSGFRKTIQWYLDHEEWWRGILSGE
                     YRLERLGTNG"
     CDS             complement(7446..8390)
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="MTSGGDAAGMNPAIKAAVDHARQLGMNPYVVYDGLEGLIDGKIKE
                     ATRELTNDMIYRGGTLLRSSRSKRFFDYEFRKQAYEHLKERNIDKLIIMGGDGSFRALN
                     DFFNDFEVPFAGIPATIDNDIAGTDYCLGVDTAQNVILDCIDSVRDTARSHHRAFVIET
                     MGRDCGYLAMTTALCSAADICIVPEIPYDLESIYKRLQPVINEEGSCIIAVVAEGTRVA
                     QYLTRWLTERAGMDTRLTVLGHVQRGGSPTARDRLMGTRFATRAVEALNNGDINQIMVY
                     HDGQYGYASLDSVAGQQYSVNQDIINLCRELSC"
     CDS             8519..9250
                     /locus_tag="ctg11_9"
                     /transl_table=11
                     /translation="MNDTAAAILKATAALRDGTEKLRFESPVHVTYNPLTYAWGPHEQY
                     VRTYGNGEKSHLFLGMNPGPFGMAQTGVPFGEVDAVVNWLHIRGEVGRPEHTHPKRPVE
                     GFGCPRSEVSGRRLWGLFAEAFGTAENFFRHNYVANYCPLIWMGATGANITPDKLPAEQ
                     RAAVDAVCMEHLLSLITILNPHTLVGVGAYATQKLRDAASRLPGKSFTIGTLLHPSPAS
                     PIANKLWPEHPIQQLKELGIL"
     CDS             9619..11085
                     /locus_tag="ctg11_10"
                     /transl_table=11
                     /translation="MAISDYIVTIGLEVHCQIKTKSKMFCSCETGFGFEPNTRVCPTCL
                     GLPGALPVLNEFAIERTLLTGLMLGCSSPEISQWDRKNYFYPDMAKNYQTSQLDLPLCL
                     GGEVPLYPWSYPNDVIKAGIPPFRTVKLTRIHLEEDAAKITHHANYSLIDYNRAGSALM
                     EIVSEPDIDTPEEAYAYLKSLQQILNYGDISDADMEKGQMRCDVNISLRPHGQKELGAK
                     VEMKNINSMSAVRRALHYEIQRQAEELDMGIPQIQSTRRWDDERGESVVMRTKEDAHDY
                     RYFPCPDLVPVRTAPLVEKVRGQIPELPQERQKRFMEEYGLSEYDANVLVGDLELARFF
                     EEAARGTASGKKIANWVINNISAVLNEKGMRPSECPVKPGAIRELIAIIDDGTVSNNQA
                     KDVFAKMWDEPALAAAQAAKLLGFEKADSSFLDGIVREVISANPDKVAEIQGGNEKLLN
                     WLTGQVMKAAKGKANPKIVTEALKKALSME"
     CDS             complement(11140..12906)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_11"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-33, bitscore:
                     108.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLEVGWCLICMYRVADQIVEILEKAGVKRIYGIVGDSLNPVTD
                     ALRRRKTIEWIHVRHEEVAAFAASAEAQLSGNLAVCCGSSGPGNLHLINGLFDAHRNHA
                     PVLAIAFHIPQSQVGMEYFQATHPEQLFKECSAYAELVSEASQAPSILMSAIQHAWARR
                     DVGVVVLPGDIADAPAEMKNLVHPPSYTRENVVPEHESVSLLARMLDDHRRITFFCGAG
                     CAGAEDKVVRLAHRLKAPIAYTWRGKDHFEHDNPLGIGMTGLLGWGDAYKAMHESDMLV
                     LWGTDFPYFNFIPTKPEIVQIDRRGEVLGRRCRLDLGICGDVSVTAEALLNMVQEKTDS
                     GHLDAALKRHARDVKEMNAYMEGNDKESPIRPEQLTTALNRHAASDAVFTVDTGTPCIW
                     SARFLCATPGRRTLASFNHGSMANAMPMAIGAQMEYPERQVIALCGDGGLSMLLGDLIT
                     IVQYRLPVKIVVYNNDCLDFIQLEMQAAGLIPWQINLNNPSFAAVADAVGIKGFLLDKS
                     SQVDQMVDMFLNYPGAALLDAHVDRDALALPPYISMGQAADFSLAMMKQTLAGEVKQVW
                     NTLAGNRKLFKP"
     CDS             complement(13035..13763)
                     /locus_tag="ctg11_12"
                     /transl_table=11
                     /translation="MAIAACCSVPALASPGSLEPSAGTSYVAGTATTTEGIALGKDMTF
                     GSLSQSALPGSSIPYGGNFYASNYTISLWLDTSSLTEGTQTTLFGYYGTNVGQSYGTNA
                     LYLTSDAKLGMGDGNLNTSTGSFSQNRGDVSEASVVLGGGLLNVTLAVTGADQSQSVDV
                     YVNGSLLDTLSYNGNMNGNRSDIQSWINPNLTWGEIQWTDTKLSAEQIAGFAGLQVPEP
                     ASASLGILGLAVLMMRRRRS"
     CDS             13940..14071
                     /locus_tag="ctg11_13"
                     /transl_table=11
                     /translation="MNIKNKTQNRFFVEVLKLLYRNSNPFSQNRKNCNNSFIIEMLD"
     CDS             14238..16775
                     /locus_tag="ctg11_14"
                     /transl_table=11
                     /translation="MKFFKTTIAMATLLGCLPTSPAEVAFPGPAPGTASAEQSASGYTL
                     SNNILTAKFILRNGSLSFGGMTSKLGPVAKAGNELFIINLQDGRSIKSSELKAGNVKFV
                     SLQPNPKAFRLADRFPGKAVSATFQALNGTLRISWRAVLRDHSHYLRQELHLASMKPVQ
                     MKNIVAMQYDLAEGKAGAPSVSGNARGALIVNDLAFTALETPMGINTVGGAGNMEGGET
                     AIWNADKWSTASWTGNFNVPQELKKQYGEQVSSAEGPVSIDGKGACTITFQYKGGDKGN
                     NKLNLAGVQLLSSRGAVLDSDFHNGSTGDSNAGNTYTVQVPSRGNYILRYWAQTKSEPI
                     ASKGEITFSLPVRTLEEKQEPQADESRLAQGLWSRKTTLQPGEIWDVSSVLGIFAPGQK
                     RRSFLAYMERERVMPYRPFIHYNSWYELNINRNNDSDPAKRMTEEQCLAVLKDWQEQFF
                     QKRGMSIDAFVWDDGWDEFNSLWDFHKMFPQGFKRIDAAAGRQKAGIGTWLGPVGGYGA
                     SKGKRLAYWNVKHPDNKIGNFQLSNKEYFDAFVGRCSQMVKDYNMKYFKFDGISTHFHA
                     KGPGNEEDAEGIIRVLNALRKKKGDLYINCTVGTWASPFWFRYADSVWRQENDFGTIGA
                     GDNRDKWITYRDRLVHEVFVQGSPLMPINSMMTHGLMVTKFGPPACMPRDPENVKKELR
                     CATACGTSLQELYVDRDLMSANGGVLWDELAKGIKWIRRNADVLDDVHWVGGNPWNKET
                     NEGAVYGWAAWNKNKATLALRNSSDQEKSLTGTLRSILDIPANVKGSITFKDSYDDQRT
                     LDGFSGSSVDIDKEISFTLKPFEVLVYEGGKVK"
     CDS             complement(16886..17539)
                     /locus_tag="ctg11_15"
                     /transl_table=11
                     /translation="MWNDLSHGFSVLADALAFLSRSWGFWVCAGSVAGLAAVYAWWRKR
                     LALWAFVLAFLSLLAVVGLACRQAVCQKVFLWIHEPDVQALSGKYEVEPSPRERRFFRP
                     PELKRFFQVSSSTLLLNEDGTCEISSFPRPEAWGRWIARPEEREDLSVLEEDLVSSCRG
                     TWSLVKKGGYYGVSIAYSPGRSLMLYLGGEGAECLVMPVNPADPLEAVTFEKTF"
     CDS             17706..20462
                     /locus_tag="ctg11_16"
                     /transl_table=11
                     /translation="MKSAAHHQGLSEQQVLENRTRYGINILTPPEKEPLWKQFLEKFSD
                     PIIKILLVALLLSVGVAFYQFFTGTESASVFLEPAGILAAILLATCVGFAFEVSANKKF
                     EILNQVNDDTMVQVIRGGNICELPRRDVVVGDIVILNTGEEIPADGVLLEAVSLQVNES
                     TLTGEPLIGKTTNEAEFKKDATYPSNHVLKGTTVADGHGVMEVTSVGDKTEYGKVYEGS
                     QIDNKVQTPLNRQLSRLGDLITWASYAIAALIVIGRLTLYFSHLPGPVEWLSAGTYILN
                     TVMIAVTVIVVTVPEGLPMSVTLSLALSMKSMLANNNLVRKMHACETMGAATVICTDKT
                     GTLTRNQMNVYKADFYGLGNAVPTEDEPGNLIREGIAVNSTAFLDYADPEHIRALGNPT
                     EGALLLWLHGLGVNYLDLRENARVLEQLTFSTERKYMATVAESPLLGKKVLYVKGAPEI
                     VLGLCSTVLTPEGQVPAADMRPAIEEQLLAYQNQAMRTLGFAYRILEDDAPVFEDGRII
                     RKDLVYLGITAISDPVRDDVPQAVKDCMDAGIRIKIVTGDTPGTAREIGRQIGLWTEED
                     SPDRLMTGVEFEQTPDAELLDRVMDLKIMCRARPMDKERLVKLLQKKDQVVAVTGDGTN
                     DAPALNAAQVGLSMGDGTTVAKEASAITILDNSFMSISRAVMWGRSLYRNIQRFIVFQM
                     TINVAACLIVLIGAFLGTESPLTVTQMLWVNLIMDTFAALALASLPPDERVMQDPPRKT
                     TDHIITRPMGRNILGVGILFVAFLFGLLQYFKHADITSLTQFSLSGYFRSYLDFSAPEH
                     ELTGYELSLFFTIFVLLQFWNMFNAKAFNTHQSAFARMGASIGGFGLVALLILAGQYLI
                     VTFGGKMFNVVPLSWTDWGLIFAGTSLVLWFGELARAFTPDKSGARS"
     CDS             20489..21718
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_17"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 5.4e-09,
                     bitscore: 28.7, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTATPPGKPSFNKGARRRVIPSMDLTRLTGSISSPAVFLFLLS
                     LFFAGCKKTEQVPHETPTLIYEHPVTMDIPVTGSWVGHLDGVDNASIVPQITGYLQTQN
                     YANGAIVKKGEVLFRIDDSTFRDQVSKAKATLAQAQAQLQQLNYDAEIYRPLAAENAIS
                     KQKYEDTRLSALAAEAQVQQAAAALALAEKNLSYTVLYAPFDGIAGISRTNIGDLVSPE
                     SGPLAVVSSVNPIRVNFAVTQQEWIQQAGKNGNEGVQTGSKLDITLKDGTKYPEQATVV
                     AIDRAFNPQTGTIRVQANLPNADYLLRPGMFIIATARLATVKNALTVPAKSLLSTQGRF
                     FVIVLDGSNHPSIIPVQAGTQLGDRQQVIPLKPDSLTPQSKVVVDGLLQAEAASRNPAA
                     RLKAVPASNQ"
ORIGIN
        1 cccgcacctg ctccggctcc ggccgccgcc ggcgcaggag acgttcccag cccgcttgcc
       61 gggaaggtcg tctctctgga cgtggcagca ggcacccccg tgaaggccgg tgaccagatt
      121 ctgacgctgg aagccatgaa gatgaacacc atcatctacg ctcccgcctc cggcacgctc
      181 accgctttct gcgtgaaccc gggcgacacg gttcaggaag gacaggcact ggccaaaatt
      241 ggttaatccc ggcggcggca gcccggaaac gccaacagtc ccgggctccg gctcagataa
      301 taaaccgcta caaaaatatt ccctatgagt ctttttgatt cattaatcac ctttttacag
      361 gggatgggcg tcttctccct atcatggcag atggtaggga tgtggggcat tgccattctc
      421 ctcctgtatc tgggtgtagc caagcaatac gaaccgctcc tgatggttcc cattgctttc
      481 ggcgccctca ttgccaacat tccggataac ggaatgctca tcacccagct gaaccagcag
      541 gtcatctcct ccaatgaaca gggggaagta accgccacgt ctctgaacaa cgtggggtac
      601 ctgcgcgttc acgtggctcc gcttcagcag gctccctcca aggtgccggc caacctgacc
      661 acgcctgaat cccgttccca gtatcaggaa atcatgcagc agcccatgca ggtttacccc
      721 ggcagccagc tgactgtttc caagatcaag tccgtgcggg aatcccagga aaaagcaaaa
      781 gctgacgcgg cccgtctggg cgacgacagc ctgacggtgg accccaacct gaaggatttc
      841 cagaacgtga cggaagacaa cggcaatgaa ccggtctttc tgctcacgaa cggagaaggg
      901 accaccgtcg tccgccagca gggcgtcaat tactttgaca ccagcggcaa ccggattccg
      961 gtggatctga aaacccagaa gctggagccc ctggtggttt cagccgcagg caaatacgtg
     1021 gccgtaggcc agcataccca ggaactgctg gtcacctcca tccacggggg cctgtatgac
     1081 tggatcgggc tgggcatcaa ggctgaaatt ttcccgccca tcatctttct gggagtagga
     1141 gccctgacgg acttcggccc gctgcttgcc gctccgcgca ccctgcttct gggcgcagcg
     1201 gcccaggtgg gcgtagccgc cacgttcttc atggccctgt tcatggggtt caccccgaat
     1261 gaatccgcgt ccatcggcat cattggcggc gctgacggcc ccacctccat cttcctgacg
     1321 atgaagctgg ctccgcacct gctgggcgcc gtggccgtgg ccgcatacac gtacatgtcc
     1381 ctggttccgc tgatacagcc gcccatcatg gcgttgctga cgaccaagaa ggaacgcctc
     1441 atccgcatga aatccctgcg aacggtcagc aagagcgaaa aactgttctt cgccgtgctg
     1501 gtaaccattg tcaccatttt gctgattccg gacgcatccc cgctgatcgg catgctgatg
     1561 cttggcaact tcctgcgcga atgcaaggtg acggaacgcc tggttcaggc ctcccagaat
     1621 gaaatcatca acatcgtcac catcttcctg ggaacctccg tggggctcac gatgcagggc
     1681 gaccgcttcc tgcagtcgga aacgctgctg atcattcttc tgggtatcgt cgccttcggc
     1741 gtggcaacag cgggcggagt gattgccgcc aagattatga acctcatctg gcgcaagaat
     1801 ccggtcaacc ccctgatcgg gtccgcaggc gtctccgccg tcccgatggc agcccgcgtc
     1861 tcccacaatg tgggccagaa gtacgacccc tccaactacc tgctcatgca cgccatgggt
     1921 ccgaacgttg caggcgtgat cggcaccgca gtcatcgcgg gttactacat cgccactctg
     1981 gcgaaataac cagaattgaa aattactccc ggcctcggcc cgtcccatga attccgcagc
     2041 ctcattttcc acccctccgg aggaggaagg accatgcggc gactggactt atcatgaatg
     2101 ggccgaggct ttttccacca atgatctggc ccgagccctc cccccggggc atattgccgt
     2161 ctgccgcgtt cagacaggag gccgcggcag gttcaaccgc aaatggatag gggaggaagg
     2221 cggcctgtgg gcatccttca ccgtccccct gtccgctcct gaggatacag cggccggcgt
     2281 gcactggggc catttgcccc tggttgcggg gctggccctg ttcaacatgc tccgcggcat
     2341 ggggctggat tccgtgcgcc tgcgctggcc gaacgacctg ctggcgggca aatccaaact
     2401 ggcgggaata ctggtggaac gcccggcgga gaacatggcc gtcatcggca tcggcatcaa
     2461 tgttttcaat gatgtatcct ccatcgccgg ggaaatcaag gaccctccgg caaggctggc
     2521 ggatcttgtt cgggactgcc cttccctgca cgccgtcatg gcttccctgg gcagtcattt
     2581 gaaccaggtt ctttccgtct tttcccacgg cggcgtcccc gcccttcagg aggggctgtc
     2641 ccgggcatgg gccggagaaa ggccggtttc cattcttacg gatgacgaaa ccgtccgggg
     2701 catttttaca gggattgacg atcagggcaa tcctgtgcta tcccttccgg ccggcaccgt
     2761 ccgcaccatt ccggcgcacc tgatcaacag gctcctcgaa gaatgagcct gccgctccgt
     2821 ttttacacgg ggtttctttc ttttttcatc caacaaaaat cactgacatg agttacaagg
     2881 tactgacacc agaagaagca gcaagcctga tcaagcatgg ccaccatatt gggctgagcg
     2941 gattcacgcc cgccggaacg gccaaggccg ttacggctgc gctggcaaaa atcgcagaag
     3001 cggaacatga gaaggggaac cctttccagg tgagcgtctt caccggtgct tccactggcg
     3061 attcctgcga cgggatcctt tcccgggcca aggcaatccg ctaccgcgct ccctacacca
     3121 ccaacgttga tttccgcaag gcggtgaaca acggggaaat cgcctataat gacatccatt
     3181 tatcccagat ggcccaggaa gtgcgctacg ggttcatggg caacgtggac atcgccatta
     3241 ttgaagcctg tgaagtcacg gccgacggca aaatttacct gacggccgcg ggcgggatcg
     3301 ctcccaccat ctgccgcctg gcagacaaaa ttatcgtgga attaaacgcc gcccacagca
     3361 agagcgccat gggcctgcac gacgtttacg aacccctgga tcctccctac cgccgcgaaa
     3421 tctccatctt caaacccagc gaccgcatcg gcaagccgta catccaggtt gacccgaaaa
     3481 agattgtggg cgttgtggaa accaactggc cggatgaagc ccgttccttc gccgcagcgg
     3541 atcccctgac cgataaaatc gggcagaacg tggccgattt cctggctgcc gacatgaaac
     3601 ggggcatcat tccctccacg ttcctgcctc tccagtccgg cgtaggaaac atcgcaaacg
     3661 cggtgctggg cgccctgggc cgcgacaaga cgattcccgc gttcgagatg tacacggaag
     3721 tcatccagaa ttccgtcatc ggcctgattc gggagggccg cgtgaaattc ggcagcgcct
     3781 gctccctgac cgtgacgaac gactgcctgg aaggcattta cagggatatg gactttttcc
     3841 gcgacaaact ggtgctccgt ccctcggaaa tatccaacag cccggaagtt atccgccgtc
     3901 tcggcgtcat ctccatcaac accgccattg aagccgacat ttacgggaac gtcaactcca
     3961 cgcacattgg cggcacgaag atgatgaacg gcatcggcgg gtccggcgac ttcacgcgca
     4021 acgcctacat ctccattttc acctgcccgt ccgttgccaa ggacggcaag atcagcgcca
     4081 tcgtccccat ggtttcccac catgaccata cggaacatga cgtcaatatc attattaccg
     4141 agcagggggt cgcggacctg cgcggcaaga gcccgaaaga acgggcccag accattattg
     4201 aaaactgcgt ccacccggat tacaaaaaca tcctctggga ttacctgaag ctgtccgacg
     4261 gcaaagccca gacaccgcaa tccatcaggg ccgctttggg catgcacgcc gaactggcca
     4321 gaagcggaga catgaagaat gtcgactggg cccagtataa gtaattccgc atgccgtcat
     4381 tcgcattggc atccatgaat tcacgttaac ccctcaggac cgcttccgca aagggagcgg
     4441 tccttttcct ttttcccatc ccctctactc tcttctcttc gccatgaact ggatgattta
     4501 cccggcagcc agggctttca tcaaagtctg ctccgttctt ttcggcacgg gcgcagcagc
     4561 ggcagtcctc atccatctgt tcatgccttt tttcctccgc tctccccgga cagccgcgcc
     4621 cttcctgctt ttgggaacag gggcggaact gctctccatc ctttccctgt ccttcctcat
     4681 gttctggggc gtcagagttc tgctggcctc ccgcggaagc agaataacaa gaaatctgag
     4741 catgctggcc ttcctgcccg ccctgtacgc cctcctcatt ccgtttgcgg gcatgcccgt
     4801 cccatcgcaa tatacggaaa tggacagggt ttgggaggcc gtcctccttc tgtcggccgt
     4861 cacttctttc ttttccttcc cttatacggc gggatacggt gccgcaggca ggagattatt
     4921 cctggcctgg ggcatcgcag cggcaggctg cggtttgcag agcgccctgt tttttcttgc
     4981 cgtcctgttg cgtcagttcc tgtccaccgc agttccctcc ctggcagcgc ctgttgcatg
     5041 gctggccgtt cttctgtcct gcggcctgga aatcatgctg gcggcccttt ccgctattct
     5101 ggcgcagcgc ctgtttaaag aggtcatgtc catagcatcc atgccggaac cgattgatcc
     5161 ttccatgccg ggcaaccgtc cctgactttc ctcccctccg tttttaccgg cctgccggaa
     5221 gagcaccctc attccccggc atgaaaggct tttacggctt tgcgcaaaaa gccgtccgga
     5281 aatttccgcc ggtggaacgg aatccgtatg gaaagcaacc cgccccaccc cggaaagccg
     5341 cgggttcgca ggccccccct cccgtttcca cgccgacggc agacagccct atttcaccaa
     5401 ttcatccaga taacggccat aaccgttatt attcatggct ccggcctggg agcgcagcgt
     5461 ttcctgggaa atccagccgt tattaaaggc tatctcctcc aggcaggcta ccttgaaccc
     5521 ctggtgatgc tccagagtac gaacgaacat ggaagcctcc agaagggtat cgtgcgtgcc
     5581 cgtatccagc cacgtatagc cgcgcgccag tttttccacg cgcaacaggc cctgcttcag
     5641 gtattcctga ttcacagagg tgatttccaa ctcgccgcgg gaagacttgg gaatccgttt
     5701 ggctatctcc accacccggt tgtcgtaaaa atagaggccc gtcaccgcaa tatccgattt
     5761 gggcctgggc ggtttttcct caatggaaac cgccttcccc tcctcattga attccactac
     5821 cccgaaacgc tgcgggtcat gcacctggta accgaaaatg gtcgctccgc tcgtcagttc
     5881 ggcggccctc ctcagcttct ccgtcaggcc gcgcccgtaa aaaatattgt cccccagcac
     5941 cagggcaacg gaatcctttc ctatgaactc ctctccaata ataaaagcct gagccagccc
     6001 ctccggcctg ggttgttccc tgtatttaaa ggaaacgccg aacctgctgc cgtcccccag
     6061 caaatcccgg tacaggggca gatcccgggg cgtggaaata acaaggattt cccgtattcc
     6121 ggccagcatc agcacggaga tgggataata aaccatcggc ttatcataaa cgggcagcaa
     6181 ttgcttgctg acggaaagcg taacgggatg cagacgcgtg ccgcttcccc cggccagaac
     6241 aatacccttc atatcaaatt cctagccatt ggttccaaga cgttccaggc ggtattcccc
     6301 ggacaggatg ccccgccacc attcctcatg gtccagatac cactgaatgg tctttctgaa
     6361 tccggaagaa tggtcctggc gcggagtcca ccccaattcc ctccgtattt tggaagcgtc
     6421 aatcgcatag cgcaggtcat ggcccggcct gtcctgcaca aaggagattt gctcccggta
     6481 gctccggccg tccggacggg gccgcagttc atccagatgg gaacacagca gttccaccag
     6541 ctccagattg gttttctcgt tattgccgcc gatgttgtac gtttcccccg gttttccgca
     6601 ggaaacgacc gtcaacagcg cctcgcagtg atcccccaca tacagccagt cccgcacgtt
     6661 ttcccccttg ccgtatacag gaatgggttc cccgcccagc gctttcagga taacgacggg
     6721 tatcagcttt tccgggaact ggtaagggcc gtaattgttg gaacagttgg tgatcagcac
     6781 gggcagcccg tacgtatcgt gccaggcgcg caccaggtgg tcgctggagg ccttgctggc
     6841 ggaatacggg gaatgggggc gatacggcgt ggactccgtg aacaggcctt cctttcccag
     6901 ggagccgtac acttcatccg tggaaatgtg gtggaagcgg aaacgctcct ttttctctcc
     6961 ctccagggaa cggtaatatt ccagggcggc ctgaagcatg gaaaaagtgc ccatgacgtt
     7021 ggtggtcata aaatttcccg gatcgtcaat ggaacggtcc acatgggatt ccgccgccag
     7081 gtgcatcacc cagtccggag cgtactcccg caaagtgcgc cgcatcaggg aagcgtcccg
     7141 gacgtcggcg tgcagaaagc ggtatgccgg agaatccgcc gagccgtcca gtgaatggat
     7201 gttgccggca taggtcagag cgtcaatatt caggacttca tggccgcgct ccagcagcag
     7261 cctgaccaga ttggagccga tgaatccggc gccgcccgta acgataactt tcatagcact
     7321 gttttcaggg aaagatgcgg cgccatcata cagcagcggc gttttttttc aaaacaaatc
     7381 cgcccatgcc gcgggaacgt ggcggcatag gcgggaaaaa gcgggttccg taaccgctga
     7441 gacggctagc agctcagctc ccggcaaagg ttgatgatat cctggttcac ggagtactgc
     7501 tgcccggcta cggaatccag ggaggcatag ccgtactggc cgtcatgata caccatgatc
     7561 tggttgatgt ccccgttgtt cagagcttcc acggcgcggg tggcaaaacg ggtgcccatc
     7621 aggcggtcac gggcggtggg ggaaccgccg cgctgcacat ggcccagcac ggtcaggcgg
     7681 gtatccatgc cggcgcgttc cgtcagccag cgggtcaggt actgcgccac gcgggtgcct
     7741 tccgccacca cggcaatgat gcagcttcct tcctcattga tgacaggctg gaggcgcttg
     7801 taaatggatt ccagatcata cggaatttca gggacaatgc agatatccgc cgcgctgcaa
     7861 agagcggtgg tcatcgccag atagccgcag tcccggccca tcgtttcaat cacgaaagcg
     7921 cggtgatggg aacgggccgt atcacgaacg gaatcaatgc aatccagaat cacgttctgg
     7981 gccgtatcca cgcccaggca gtagtccgtt ccggcaatgt cgttgtcaat cgtagccgga
     8041 ataccggcaa aaggcacttc aaaatcattg aaaaagtcgt tcagggcgcg gaaggaaccg
     8101 tccccgccca tgatgatgag cttgtcgatg ttgcgttcct tcagatgttc gtaggcctgc
     8161 ttgcggaatt cgtagtcgaa aaagcgcttg gatcgtgagg aacggaggag agttccgccc
     8221 ctgtagatca tatcgttggt cagttcccgg gtggcttcct tgatttttcc atcgatcagc
     8281 ccttccaagc cgtcataaac aacgtacggg ttcatcccaa gctggcgggc atgatccact
     8341 gccgccttga tcgccgggtt cattccggcg gcatcaccgc cagatgtcat aatggctatt
     8401 ccactcataa gtaataaggt taacttgtcc ggggggaaat gttaccgggc ggaacaaata
     8461 atgcaagcgc ggagttttta ctggcgcaat aaacggcaac acttcatgat gcggaggcat
     8521 gaacgacact gcagcagcca ttctgaaagc cacggccgcc ctccgggacg gcacggagaa
     8581 gctccggttc gaatccccgg tccatgttac ctacaaccct ctcacctatg catgggggcc
     8641 gcatgaacag tatgtgcgca cctacggaaa cggggaaaag agccatctgt tcctgggcat
     8701 gaatcccggc cccttcggca tggcccagac aggcgtcccc ttcggggaag tggacgccgt
     8761 cgtcaactgg ctgcacattc gcggagaagt cgggcggccg gaacataccc accccaaacg
     8821 tcccgtggag ggtttcggct gccccaggtc ggaagtcagc ggccgccgcc tctggggact
     8881 tttcgcggaa gctttcggaa ctgcggaaaa cttcttccgt cacaattacg tggccaatta
     8941 ctgtccgctg atctggatgg gagccaccgg agccaacatt acgccggaca aactgccggc
     9001 ggaacagcgc gccgccgtgg acgcagtatg catggaacac ctgctttccc tcatcaccat
     9061 cctgaatccc cacacgctgg tgggtgtggg tgcctacgcc acgcagaagc tgcgggacgc
     9121 cgcctcccgg ctccccggca aaagcttcac catcggcacg ttgctccacc caagccccgc
     9181 cagccccatc gccaacaagc tctggccgga acaccccatc cagcagctta aggaactggg
     9241 cattttataa aaagagcgga ggaggtagag tggaaagctc cgtgacatgg aaggaatcac
     9301 cagagcgaca ggccggaaat cggcagttca tcttgttctc ctccaaatct acatcgtttt
     9361 gaaggaatat ccggccccct ttactggctt gatttgccca gggacacagc cttcctgacg
     9421 gaagaaaagc acgccggcat ctaccgggac agagaagaac ttaaacgcct ccccacttcc
     9481 accacaaaaa tcagcctccc tccaaatcaa tcatcattct tagactgaaa accctccgct
     9541 ctcccccgca ggccttttta ctggacaggg ggaaaagggt tccgtacagt ttccgcgatc
     9601 ttcaagcgtt ccgaatttat ggcaatttca gattacatcg tgaccattgg cctggaagtc
     9661 cactgccaga tcaagacaaa gagcaaaatg ttctgctcct gcgagaccgg ctttggcttt
     9721 gaacccaata cgcgcgtgtg ccccacctgc ctggggctgc cgggcgccct gcccgtcctg
     9781 aatgagttcg ccattgaacg cacgctgctg accggcctga tgctgggatg ctccagcccg
     9841 gagatttccc aatgggaccg caaaaattat ttctatccgg acatggctaa aaattaccag
     9901 acctcccagc tggatcttcc gctgtgcctg ggaggggaag tgcccctgta cccctggtcc
     9961 tatccgaatg acgtgatcaa agccggcatc ccccctttcc gcaccgtgaa gctgacccgc
    10021 atccatctgg aagaagacgc ggcgaagatt acccatcatg ccaattattc cctgatcgac
    10081 tacaaccgcg cggggtccgc cctgatggaa atcgtttccg agccggacat cgacaccccg
    10141 gaagaagcct acgcctacct caagtccctc cagcagattt tgaattacgg ggatatctcc
    10201 gacgcggaca tggaaaaggg ccagatgcgg tgcgatgtga atatttccct gcgtccccac
    10261 gggcagaagg aattgggcgc caaggtggaa atgaagaaca tcaactccat gtccgccgtc
    10321 cgcagagccc ttcattatga aatccagcgc caggcggaag aactggacat gggcattcct
    10381 caaatccagt ccacccgccg ctgggacgac gaacgcggag aaagcgtcgt catgcgaacc
    10441 aaggaagacg cgcacgatta ccgttatttc ccctgtccgg atctggttcc cgtacgcacg
    10501 gccccgctgg tggagaaagt gcgcgggcag attcccgaac tgcctcagga acggcagaaa
    10561 cgcttcatgg aagaatacgg cctgagcgag tacgacgcca acgtgctggt gggagacctg
    10621 gaactggcac gcttttttga agaggcggcg cggggaaccg ccagcggcaa aaaaatcgcc
    10681 aactgggtga ttaacaacat ttccgccgtg ctgaatgaaa aaggcatgcg cccgtctgaa
    10741 tgcccggtga aacccggcgc catccgggag ctgatcgcca ttattgacga cggcaccgtt
    10801 tccaacaacc aggccaagga cgtattcgcc aaaatgtggg atgagccggc cctcgccgca
    10861 gcgcaggccg ccaagctgct gggctttgaa aaggcggatt cctcttttct ggacggcatc
    10921 gtgcgggaag tcatttccgc caatccggac aaggtggcgg aaatacaggg gggcaatgaa
    10981 aagctcctga actggcttac cggccaggtc atgaaggccg ccaaaggcaa agccaacccg
    11041 aaaatcgtga cggaagcgct gaaaaaagcc ctttccatgg agtgaccata aacaaagagc
    11101 cgcttccctt gccgatgccg gctccttgcc cgcagggcat cacggtttga acagcttcct
    11161 gtttccggcc agggtgttcc atacctgctt cacttccccg gccagcgtct gcttcatcat
    11221 ggcaagggaa aagtccgccg cctggcccat actgatgtag ggaggcaggg caagggcgtc
    11281 cctgtccaca tgcgcgtcca gcagagcggc gcccggataa ttcaggaaca tgtccaccat
    11341 ctggtccacc tggctggatt tgtccaataa aaaccccttg atgccgacgg catccgccac
    11401 ggcggcaaaa gaggggttgt tcaggttgat ctgccacgga atcagcccgg ccgcctgcat
    11461 ttccaattgg atgaaatcca gacagtcatt gttatacacc acgattttca ccggcagcct
    11521 gtactggaca atcgtgatga gatcccccag cagcatggac aggccgccat ctccgcacag
    11581 ggcaattacc tgccgttcgg ggtattccat ctgcgcccca atagccatcg gcatggcatt
    11641 ggccatggag ccatgattga aggaagccag cgtcctcctt cccggcgtgg cgcacaggaa
    11701 cctggcgctc cagatacagg gggtgccggt atctaccgta aatacggcgt cggatgccgc
    11761 atgcctgttc agggcggtcg tgagctgttc cggccggatg ggagactcct tgtcatttcc
    11821 ttccatatag gcgttcatct ccttcacgtc cctggcgtgg cgtttcaggg cggcatccaa
    11881 atgcccggaa tccgtctttt cctgcaccat gttcagcaga gcttccgccg tgacggaaac
    11941 atccccgcaa atacccaggt ccaggcggca gcggcggccc agcacttcac cgcgcctgtc
    12001 aatctgcacg atttcaggtt tggtgggaat gaaattgaaa taggggaaat ccgtccccca
    12061 caacacgagc atgtcgcttt catgcatggc cttgtaggca tctccccatc ccagcagccc
    12121 cgtcatgccg atgcccaggg gattgtcatg ttcaaaatga tcctttcccc tccatgtgta
    12181 ggcaatcgga gctttcaggc ggtgcgcgag ccggacgacc ttgtcttccg ctcccgcgca
    12241 gccggcgccg cagaagaaag taatgcggcg gtggtcgtca agcatccgtg ccagaaggga
    12301 tacggattca tgctcaggaa caacattctc ccgcgtgtag gaaggaggat gcaccagatt
    12361 cttcatctcc gcaggggcgt ccgcaatgtc tccgggcaag acgacgacgc ctacgtcgcg
    12421 cctggcccac gcgtgctgaa tggcggacat caaaatggac ggggcctggg aagcttccga
    12481 aaccagttcc gcatatgcac tgcattcctt gaaaagctgt tccggatgcg tggcctggaa
    12541 atattccatg cctacctggc tctgcgggat gtggaaagca atggccagca ccggggcatg
    12601 gttccggtgg gcgtcaaaca ggccgttgat caaatggagg ttcccggggc cgctgctgcc
    12661 gcagcataca gccagattcc cgctcagctg ggcttccgcg ctcgcggcaa aagccgccac
    12721 ttcctcatgc cgcacatgaa tccattcaat ggtcttcctc ctcctcaaag cgtccgtaac
    12781 ggggttcagg ctatccccca caatgccgta aatccgctta actcccgcct tctccaaaat
    12841 ttcaacaatc tgatcggcta ccctgtacat gcagattaga caccagccaa cctccaacgg
    12901 attcattctt atgtgtcatc ccctccatct tttccgcacc ggaaaaaatg cctgaggatt
    12961 tcccctgata tcataaagcc gccgcctttt caggcagcgg cctatgaatt taccagttct
    13021 ctggtggaaa accgtcagga acggcggcgg cgcatcatca gaacggccag gcccaggatt
    13081 cccagagaag ccgaggccgg ttccggaacc tgaaggccgg caaaaccggc aatctgttcc
    13141 gcggaaagtt ttgtatccgt ccactgaatt tcaccccatg taagattggg attaatccag
    13201 ctttggatat cagagcgatt tccgttcatg ttgccgttgt aggacaacgt gtcaagcaag
    13261 gaaccattca catagacatc cacagactgg ctttggtctg cgccggtaac ggccaaagtc
    13321 acgttaagaa gacctccccc caaaacaacg gaagcttcag aaacgtctcc acggttttgg
    13381 gaaaaagagc cggtagaagt attcaagttc ccatctccca tgcccagctt ggcatctgac
    13441 gtcagataca aggcatttgt cccgtaactt tggcccacat tggtgccata atacccaaac
    13501 agcgtggtct gggttccttc cgttaaggaa gaagtatcca gccagaggga gatcgtgtaa
    13561 ttggaagcat aaaaattacc gccgtaagga atggaactgc caggaagggc actttgtgag
    13621 agacttccaa acgtcatgtc ttttcccaat gcaatacctt cggttgtcgt cgccgtaccg
    13681 gcaacgtaag acgttccggc cgatggttct aaagagccgg gagacgccaa cgccggaacg
    13741 gaacaacacg ccgcaatggc cattaatgct aatgtttttt tcattttctg tgaatgatgg
    13801 actgagtagc aatcagagag atattccccg ccctctgtat atcggattcc caatccgctc
    13861 tttttctccc ccacaggaaa gatgagaaca agctttttca atccgctaaa aaatataata
    13921 taattacctt ctatcactta tgaatataaa aaataaaacg cagaatagat tttttgtgga
    13981 ggttctgaag ttgctgtata ggaacagcaa tcccttttcg caaaatagaa aaaattgtaa
    14041 taatagtttc ataattgaaa tgttagattg acctcggatt gggaatccgg ttgttttccc
    14101 tcagccatca aaaaaatcaa cataatgttt tcatattcaa taaaaattaa ttttctttcc
    14161 ttccatttcc agaaccttct tcttgaaaac gagccttccc caaattatcc tcccgctagc
    14221 tgtaatatta tttcatcatg aaatttttca agacaaccat tgccatggca accctgctgg
    14281 gctgcctgcc cacatccccc gcagaagtcg cctttccggg gcctgcaccc ggaacagcca
    14341 gcgcggaaca atccgcttcc ggctatactc tttccaataa catcctgacg gccaaattta
    14401 tccttcggaa cggaagtctt tccttcggag gaatgacttc caaactgggc cccgtcgcca
    14461 aggcagggaa tgaattattc atcatcaatc ttcaggacgg acggagcatt aaatcctccg
    14521 agctgaaagc gggaaacgtc aaattcgtct cccttcagcc caaccccaaa gccttcaggc
    14581 tggctgaccg cttcccggga aaagccgtca gcgcaacatt ccaggctctg aacggaaccc
    14641 ttcgcatttc ctggcgcgcc gtgctcaggg accattccca ttacctgagg caggaactcc
    14701 acctggcaag tatgaagccc gtccagatga aaaacatcgt agcgatgcaa tatgacctgg
    14761 cagaagggaa agccggggca ccctccgttt ccggaaacgc cagaggagca ctcatcgtca
    14821 atgacctggc gttcaccgcc ctggaaactc ccatgggcat caataccgtg ggaggcgccg
    14881 gaaatatgga agggggagaa accgccatct ggaatgcgga caagtggtcc acagcttcat
    14941 ggaccggaaa tttcaatgtt ccccaggaac tgaaaaagca gtacggagaa caggtttcca
    15001 gtgcggaagg cccggtttcc attgacggca aaggagcatg taccatcact ttccagtata
    15061 agggagggga caagggcaac aataagctga accttgccgg cgtgcagctc ctctcttcca
    15121 ggggggccgt tcttgactcc gatttccaca acggcagcac cggagattcc aatgccggca
    15181 acacttacac ggtacaggtt ccctccaggg gaaattacat tctgcgctac tgggcccaga
    15241 ccaagagcga accgattgcc agcaaggggg aaatcacctt ttccctgccc gtgcgcacgc
    15301 tggaggaaaa gcaggaaccc caggcggacg aatcccggct ggcccaggga ctctggagcc
    15361 gtaaaaccac cttgcagccc ggggaaatat gggacgtatc ctccgttctc ggaatttttg
    15421 cccccggcca gaaacgccgc tccttcctgg cctatatgga acgggaacgc gtgatgccct
    15481 accgcccctt catccattat aactcctggt atgaactgaa catcaaccgc aacaatgatt
    15541 cggaccccgc caagcgcatg acggaagaac aatgcctggc cgtcctgaaa gactggcagg
    15601 aacagttttt ccagaagcgc ggcatgtcca ttgacgcctt cgtctgggac gacggctggg
    15661 atgaattcaa cagcctgtgg gatttccaca aaatgttccc gcagggcttc aagcgcattg
    15721 acgccgccgc cggcaggcaa aaggccggca tcggcacgtg gctgggtccg gtggggggct
    15781 acggagcctc caagggcaag cgtctcgctt actggaacgt gaagcatccg gacaacaaga
    15841 tcggcaattt ccagctctcc aacaaggaat attttgacgc ctttgtgggc cgctgttccc
    15901 agatggtgaa ggactacaat atgaagtact tcaaattcga cggcatcagc acccacttcc
    15961 atgccaaggg gcccggcaac gaggaggatg cggaaggcat catccgcgtg ctgaacgccc
    16021 tgcgcaagaa aaagggggat ctttacatca actgcactgt aggaacctgg gcatccccct
    16081 tctggttccg ttatgcggat tccgtatgga ggcaggagaa tgacttcggc accatcggag
    16141 cgggcgacaa ccgcgacaaa tggatcacct accgcgaccg cctggtgcat gaagtttttg
    16201 tgcagggttc cccgctgatg cccatcaatt ccatgatgac tcacggcctg atggtcacta
    16261 aattcggtcc tccggcctgc atgccccgcg atccggaaaa cgtcaagaaa gaactccgct
    16321 gcgccacggc ttgcggcact tccctccagg agctctacgt ggatcgggac ctgatgagcg
    16381 ccaacggcgg agttctgtgg gacgaactgg ccaaggggat caagtggata cgccgcaatg
    16441 cggacgtttt ggacgatgtg cactgggtgg gcggcaatcc gtggaacaag gaaactaacg
    16501 aaggggccgt gtacgggtgg gccgcatgga ataaaaacaa ggccaccctg gctctccgca
    16561 attcctccga ccaggaaaag agcctgaccg gaaccctgcg cagcattctg gatatccctg
    16621 cgaacgtcaa gggctccatc accttcaagg attcctatga cgaccagcgg acgctggacg
    16681 gcttctccgg cagttccgta gacattgata aggaaatctc cttcacgttg aagccctttg
    16741 aggtgctggt gtacgaaggg ggaaaggtca aataaatcaa ccggcccaca cgcccggtca
    16801 aagccggaac ggcgttggaa aaaacatatt gggggaggcg ggattcccgc ctcccttcct
    16861 tgttcccgtg cgggcagaat ccgggtcaga atgttttttc aaacgtcacc gcttccagcg
    16921 gatcggcagg gttgaccggc atcaccaggc attccgcacc ttccccgccc aggtacaaca
    16981 tcaggctcct gccgggggaa taggcgatgg agacaccgta atatcctcct tttttcacca
    17041 gggaccaggt tccgcggcag gaagaaacga gatcttcctc cagcacggaa aggtcctccc
    17101 tctcttccgg acgggcaatc cacctgcccc atgcctccgg acggggaaag gaagaaatct
    17161 cgcacgtccc gtcttcattc aggaggagcg tggaagaact gacctggaaa aaacgcttca
    17221 actccggagg gcggaaaaac cgcctttccc tgggagatgg ttccacctca tactttccgg
    17281 aaagggcctg cacatccggc tcatgaatcc acaggaaaac tttttgacac accgcctggc
    17341 ggcacgccag ccccaccacg gccagcaggg aaaggaacgc caggacaaac gcccacaggg
    17401 ccagccgctt tctccaccac gcataaacgg cggccagccc cgccacactg cccgcgcaaa
    17461 cccagaaccc ccaggaacgg gaaaggaagg ccagggcatc cgccagcacg gaaaatccat
    17521 gagaaagatc attccacata ggtgctccag aatctccgga acatagtcaa agtcaagaca
    17581 acaatgccgc ccttcaaggc acgggcctca ggctgcgccc cgataaaaaa ctcccgtcat
    17641 cactcctgaa aatattcctc cgcgcttttc tcacaggctc caatcaggta agaagcatct
    17701 gaaccatgaa aagcgcagca catcatcagg ggctttcgga acagcaggtt ctggaaaacc
    17761 ggaccagata cgggatcaat atcctgactc ctccggaaaa ggaacccctg tggaagcaat
    17821 ttctggagaa attttcagac cccatcatca aaattctgct ggtggccctg ctcctgtccg
    17881 taggcgtggc tttctaccag tttttcaccg gaacggaatc ggccagcgtc ttcctggagc
    17941 ccgcgggcat cctggcggcc atcctgctgg ccacctgcgt ggggttcgcc ttcgaggtaa
    18001 gcgccaacaa gaagtttgaa atcctgaacc aggtcaatga cgacaccatg gtccaggtca
    18061 tccgcggcgg caatatctgc gaattgcccc gccgggacgt ggtggtgggc gatatcgtca
    18121 tcctgaacac aggggaggag ataccggcgg acggcgtcct gctggaagcc gtttccctcc
    18181 aggtcaatga atccacactg acgggggaac ccctcatcgg caaaaccacg aatgaagcgg
    18241 aattcaagaa ggatgccacc tacccctcca accacgtcct gaaaggaacc accgtggcgg
    18301 acggccacgg cgtcatggaa gtgacttccg tgggtgacaa aacggaatac ggcaaggttt
    18361 atgaaggttc ccagatcgac aacaaggtgc agacgcccct caatcgccag ctttccaggc
    18421 tgggcgatct catcacctgg gccagctacg ccatcgccgc cctcatcgtc atcgggcgcc
    18481 tcaccctgta tttttcccat ctgccgggcc ccgtggaatg gctgagcgcg ggaacctaca
    18541 ttctgaatac cgtcatgatt gccgtgaccg tcatcgtagt cacggtgccg gaagggctgc
    18601 ccatgagcgt cactctgagc ctggcgctga gcatgaagag catgctcgcc aacaacaacc
    18661 tggtacgcaa gatgcacgcc tgcgagacca tgggggccgc caccgtcatc tgcacggata
    18721 agacgggcac cctgacgcgc aaccagatga acgtgtacaa ggcggatttt tacgggctgg
    18781 ggaacgccgt cccgacggaa gacgagccgg gcaacctgat cagggaggga atcgccgtca
    18841 actccaccgc tttcctggat tacgcagacc cggaacatat cagggccctg ggcaatccca
    18901 cggaaggggc gctcctcctg tggctgcacg ggctgggcgt gaattacctg gacctgcggg
    18961 aaaacgcccg cgtgctggaa cagctcactt tctccacgga acgcaagtac atggctaccg
    19021 tagcggaatc ccccctgctg ggcaaaaaag tcctttacgt gaaaggcgcg ccggaaatcg
    19081 tgctgggtct ctgctccacc gtcctgactc cggaaggcca ggtacccgcc gcggacatgc
    19141 gccccgccat tgaggaacag ctcctggcct accagaacca ggccatgcgc acgctgggct
    19201 tcgcgtaccg cattctggag gatgacgccc cggtgttcga ggacggccgc atcatccgca
    19261 aagacctggt ttacctgggc atcaccgcca tttccgaccc cgtccgggac gatgtgcccc
    19321 aagccgtgaa ggactgcatg gacgcgggca tccgcatcaa gatcgtcacg ggggacactc
    19381 ccggcaccgc acgggaaatc ggccgccaga tcggcctgtg gacggaggag gattctccgg
    19441 accgcctgat gacgggagtg gaattcgagc agactccgga cgcggaactg ctggaccgcg
    19501 tgatggatct gaaaatcatg tgccgcgcca ggcccatgga taaggaacgg ctggtcaaac
    19561 tgctccagaa gaaggaccag gtagtggccg tcaccgggga cggcaccaac gacgcccccg
    19621 ctctgaacgc cgcgcaggtg gggctttcca tgggagacgg caccaccgta gccaaggaag
    19681 ccagcgccat caccattctg gacaattcct tcatgagcat ttcccgcgcc gtcatgtggg
    19741 ggcgttccct gtacaggaat atccagcgct tcatcgtctt ccagatgacc attaacgtgg
    19801 cggcctgcct cattgtgctc atcggcgcat tcctgggcac ggaatccccc ctcaccgtca
    19861 ctcagatgct ctgggtaaat ctcatcatgg acaccttcgc cgcgctggcg ctggcctccc
    19921 tgccgccgga cgaacgcgtg atgcaggacc cgccgcgcaa aaccacggac cacatcatca
    19981 cccgccccat gggccgaaac atcctgggcg tgggcatcct gttcgtcgct ttcctgttcg
    20041 gcctgctgca atatttcaag catgcggaca ttaccagcct cacgcagttc agcctcagcg
    20101 gctacttccg cagctacctg gatttttccg ccccggaaca tgaactgacg ggttatgaac
    20161 tgtccctgtt tttcaccatt ttcgtcctgc tccaattctg gaacatgttc aacgccaagg
    20221 cattcaacac gcaccagagc gcctttgcac gcatgggcgc cagcattggc ggcttcggtc
    20281 tggtagccct gcttatcctg gccgggcagt acctcatcgt cacctttggc ggaaagatgt
    20341 tcaacgtggt gcccctgagc tggacggact ggggcctcat cttcgcaggc acctcccttg
    20401 tcctgtggtt cggagaactg gcgcgggcat tcactccgga taaatccggc gcccgctcct
    20461 gaaccgtccg ggggaattcc ccccgcgcat gacgcggacg gcgacgccgc ccggaaaacc
    20521 ttctttcaac aaaggcgccc gcaggcgtgt cattcccagc atggacttga cacgcctgac
    20581 gggctctatc tccagccccg ccgttttcct cttcctgctt tccctctttt ttgccgggtg
    20641 taaaaagacg gaacaggttc cgcatgaaac gcccacgctt atttatgaac accccgtcac
    20701 catggatatt ccggtgacgg gcagctgggt gggccacctg gacggcgtgg acaacgcctc
    20761 catcgtcccc cagattacgg gctaccttca aacgcagaat tacgccaatg gcgctattgt
    20821 gaagaagggg gaagtactct tccgcattga cgattccacg ttcagggacc aggtatccaa
    20881 ggccaaagcc accctggccc aggcacaggc ccagctacag cagttgaatt acgacgcgga
    20941 aatttacagg cccctggctg cggagaatgc catttccaag cagaaatacg aggatacgcg
    21001 cctgtccgcc cttgccgcgg aagcacaggt gcagcaggcg gcggcggccc tggccctggc
    21061 tgaaaaaaat ctttcgtata cggtgctgta cgcgcctttt gacggaatag ccggcatctc
    21121 caggacaaac atcggcgacc tggtcagccc ggaaagcggc ccgcttgccg tcgtctcctc
    21181 cgtcaatccc atccgcgtca atttcgccgt cacccagcag gaatggattc agcaggcggg
    21241 aaagaacggg aatgaaggcg tccagacggg cagcaagctg gacattacgc tgaaagacgg
    21301 caccaaatac ccggaacagg ccacggtagt tgccattgac cgggcgttca atccccagac
    21361 aggcaccatc cgcgtacagg ccaaccttcc caatgcggac tatctgctgc gccccggcat
    21421 gttcatcatc gccacggccc ggctggccac cgtcaaaaac gcgctgaccg ttccggcaaa
    21481 atcccttctt tcgacacagg ggcgcttttt cgtgattgtt ctggacggga gcaaccaccc
    21541 ttccatcatc cccgtacagg ccgggacgca gcttggagac cggcagcagg ttattcccct
    21601 gaaaccggat tccctcaccc cccaaagcaa agtggtcgtg gacggtcttc tccaggcgga
    21661 agcagcctcc agaaatccgg ccgcccgcct gaaagcggta cccgccagca accaataagc
    21721 tcctcccgcc atggctgatt tcttcatcaa gcgccccatc ctttccatct gcctctccat
    21781 catcattgtc ctgctggggg ccttttccat tctgcgcctg cccatctccg agtacccgga
    21841 catcatcccc ccctccatcc aggtgacggc cacttatccc ggagcggact gtgaaacggt
    21901 ggtcaagtct atcgcatccc ccatcgaaca gcaaatgtcc ggcgtggacg gaatgtccta
    21961 catgacttcc gtcaacacca acaacgggca aatgagcatg atgatccttt ttgaaatcgg
    22021 cacggaagcc aacatggacc aggtgctttc ctatctgcgc tacgggcagg ccacctccca
    22081 gctgccgtcg gaagtcagcg cgctgggagt ctccctgcgc aagacaagcg gtctgcccgc
    22141 cctggtcgtc agcctgtatt cgccccaggg gacttatgac ggcctctggc tggccaatta
    22201 cgcctatatc aatatggtgg acgccatcaa gcgcgtgccc ggagtaggag acgtgcaggt
    22261 gttcggggca ggccgctacg ccatgcgcat ctggctgaac ccggaaaaga tggccgctct
    22321 gaatattacg gccagggacg tgatgctggc cgttcaggcc cagaacgccg tgaatcctgc
    22381 gggcaagata ggcgcacagc ccgctccgcc ggaccagcag ctttccttca ccgtgaaagc
    22441 tccaggccgc ctgaccagcg tgaaggaatt cgaaaatatc gtggtacgcg ggcaggacag
    22501 ttccatcgta agagtgggag atatcgcccg cgtggaactg ggctcggaaa cctacagcct
    22561 cagttcttcc gtaaacggca tgcccgccgc ttccatcggc atttacgaag cgcccggagg
    22621 aaatgccatc cagctggtgg acaatatcaa agacctgctg aaggatacgg atatgcctcc
    22681 cggcatggat tacctcgttt ccctggattc cacgctggcc gtccgcgccg ggattgaaga
    22741 tatcgtcagc acgctggtga ttgccctggg cctggtggtg ctggtggttt tcattttcct
    22801 ccagggctgg cgcggtacgc tgattccggc ctttgccgtt ccggtgtcta tcgtgggcgc
    22861 cttcatcgcc tttccattat tcggtttttc catcaatacc atctgc
//
