LOCUS       c00010_gnlPro..        16750 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PAGOFDDC_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 10:59:17
            Original ID  :: gnl|Prokka|PAGOFDDC_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16750
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16750
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2271:6750]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2272..6750
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..16750
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16750
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             93..1016
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_1"
                     /sec_met_domain="Peptidase_S11 (E-value: 1.5e-54, bitscore:
                     177.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGNVLFSHNGLQRRQVASTQKLVTA
                     MVVMGHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGTAA"
     CDS             1075..2196
                     /locus_tag="ctg10_2"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             2272..3357
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_3"
                     /sec_met_domain="GCV_T (E-value: 3.3e-87, bitscore: 284.7,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 3.2e-23, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGKVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             3428..3808
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_4"
                     /sec_met_domain="GCV_H (E-value: 1.7e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             3904..6750
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_5"
                     /sec_met_domain="Beta_elim_lyase (E-value: 1.1e-09,
                     bitscore: 30.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 7.7e-178, bitscore: 584.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALKELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGCICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGVPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYTVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSATCDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNINMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             6809..6982
                     /locus_tag="ctg10_6"
                     /transl_table=11
                     /translation="MFKNRISNPKSTLYFEYKWVIKMKGEEKQGRRNVPFSFLIHTAFM
                     LNCFLDAFVSSD"
     CDS             7105..8070
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MIFHHVFGLYALPAGVDTAWIAPQLTKAAPIFKICVPIFIFITGY
                     AMGWKTNSSPTFGSLIKTGFSHYFKFWKIYFLCLLLAILVSWAFPLPILPSVADMGWKN
                     GLLVVTGLRPCYPDWWYMALFAAATMALYPICAWITHHIAPVPSMAALLGVSLLFQSTA
                     HIPSLPGIAYSFPPFLPCFILGYMCAFLASRLSALSISQSLGAILLLALEILSIHLFSF
                     SKAKTLTVIFLFTLWCLPWITRKLRLTPLLTLLGTYSALMWLNHRFIFGYHFSWDLYGT
                     QSISVVFIVTLVSSLLLAMAMQKLFNRMIPSNPQTQSKTL"
     CDS             complement(8102..8734)
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="MSDLYEYQAIDGSSKGPVDLVLLLRARNLGRLSNRTLVRKVPGGD
                     WRPLASFIPSMTVMDDDGEPSVLPDPGSEPGGTDSGWSRKKYWIRVIKAWCRFEGRAGK
                     GELHEVFSRVGVAWLAVAGVPSFAECGLFPSLVPWVELVSPLLYVVLAVLSIPLAATMV
                     RRLHDVGRSGFFLVFLAVPFIGWLLLWYLSHGESRIGENKYGDPPWN"
     CDS             complement(8743..10902)
                     /locus_tag="ctg10_9"
                     /transl_table=11
                     /translation="MKLVSLLSVLLTSLVPCMGASGQATKPAARSVKTSKPNVIFILVD
                     DMGWGDLDSNWSQQKLNGRTVERKNEFKTPALSALAREGIQLRRHYSAAPVCAPARASL
                     LLGVHQGNSRVVRNNRFDQPIEDSHTLGTVMRDAGYDTAAIGKWGVGGGGQSHVPMTAG
                     PHQRGFNYFYGILDHLAGHFHYPSESRDVFEYNGYASNPEWKNIKDQVPQTAYSTDLFA
                     ARAKQWIVDQRKSARKTGKPFFLYLAFPAPHGNLVVPGVPYPSGGGLKGGLQWVKKEGT
                     ESVNTAFDARAEKNKDTYIHPDNSRFPNDVAKRHSTMIRRVDDAVADLIRLLKDLKIDD
                     NTMIVFTSDNGPHNEGGSDPRHWHGAQNPQFFKSYGMMDGIKRDCWEGGMRVPTLVRWP
                     ARIPKGQISLHPGQFHDWLATLADVAGVPVPARSDGVSLLPTLTGHADQQKPGIVYAEY
                     NFAGKTPEYKDFLGEHKGAQRGQQQIVFVDGLKGLRMGVKDADKDFMIFDTLNDPQESK
                     DLASSKPELQARMKAAALSNRRASLPSKTVFDSALVPAVDVKGTVSPGLRWALYEGDFP
                     WVPDFRQWKKPASAHGVTPSPSVKMNGSDKRGVELTGYVKIPEDGAYTFYLTTDENKGS
                     KAFVRLHGMELIDADKTYEPGAEVSSDLGDRKNPVYLKAGLHPIRIGYVGNSGTASKLV
                     LKWEGPGLSKQEIPASAFSHGKESR"
     CDS             complement(11321..13135)
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MTQTSSFSALGISPEILEAIEVLGFDTPSSIQEQAIPAAIGGADI
                     VGLSHTGSGKTLAFAIPALECIDPEERCVQVLALCPTRELAVQICREVDKLALFMDGVS
                     AVPIYGGSSFRPQLDALRRGVQFVVGTPGRVMDLMESGALRLDGLRMLILDEADEMLDM
                     GFLEDIEHIADAMPEAKQTLFFSATMSPEISRLVSRFMKEPVQISIERPTLTVPTIEQV
                     YYEVVFSSRIEVLSRLLDTGKIKMGLVFANTKKVVDDVVDGLTARGYPVDRLHGDMPQM
                     MRERVMDSFRKGSLRLLVATDIAARGLDVDDVDAVVNFELPRDPEDYVHRIGRTARAGR
                     KGKAITFVGRRDFSLMSRIERFIGVKLTPEPVLTAVQVDQLRTESLVDDILERLKPDAV
                     LPEELKEVEAAPEAMAAALFDLLRERTHREVQPIPEDKPARRARRMPQTGEEAESPQKG
                     DSWQHKGDTVTLFMNGGRMIGLRPKDIAGLFYNTVEMEKGAVGDIRIFPKHSLIEVDAS
                     VAPLLLEALATATVCGYEVNVREDKGAPEYSGTPRSSRRNGGFRNSYRGERDRSDRSGF
                     RGNRGGFRSDRGERWGERSRRDDRKKRF"
     CDS             13356..14132
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="MDKTPNKSQSSLLGIFINILLPVLILDYCSAGPANPLERPEGESF
                     WHIGPVWSLVIALSLPLVYGIRSLAVSRKFDLMSVVGMAGVLLTGVISIFVIGPEGRIH
                     SATPWLFAGKEALIPLILAAAVVVSRSTGTPLLNMFIYTPELFDVRRIEQTVAANGEEQ
                     AYQSLLANSSWILAGTLVASSVGNFFLSLSFMSSVIRQPEAEQQVAYNAAIGSITWWGF
                     LIIGIPILAALVFIMTRLIKQLGRLTGLSRDELLLK"
     CDS             14143..15681
                     /locus_tag="ctg10_12"
                     /transl_table=11
                     /translation="MRLHTSCILAAAIALNAAWADAPRFDRIFGSHMVLPHGKNIPVSG
                     TAAPNREITVTFGNTALKTKTDSKGKWSVTLPPMPPCGTGQTLAAVQNGDSAKLEDVLV
                     GEVWLASGQSNMLFRLNQTTTAKEDIAASGDDQLRLLNNIPQAHTNNAPYSGKDFDAVT
                     TDNFYKGQWASSSPSTSGPMTAVGYYFGKKLREGLGIPVGIIHSSLGGSEIAAWLPREV
                     INANNSFRTLRGNHWLDSPLISDWVRGRARKNISPRLNQGSPDHPYKPAFLYESGIAWT
                     TPLPITGVIWYQGESDAEIIDNAQNGMLLKTMISSWRKAFRNPEMPFVMIQLPRINDPS
                     KIRAGWPEFREMQDTVAKTVPQVYSVNTIDLGSTNADVHPPFKRPVGERAGNTALNKVY
                     GKKVPCEGPAFKAFKTSGSSILVQMEQAAGLTTTDGKKPAQFEIAGTDGIYHPATAEIT
                     NRKGGTAVIRLSSPEVKSPKNARYCWNRFVTPNLVNGNQLPARPFRTDVPVLKK"
     CDS             15703..16680
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_13"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.5e-27, bitscore:
                     89.8, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHLFLASLAATLSLGIAAQASPAKVACVGDSITFGSGLKPGEA
                     RYPQVLATLMGPDFDVRGFGNPGKTAGDYPGQAGRWYGSTREHKQALDFKADIYICNLG
                     INDTGRWWNPELFSKGYEALLQAWKNANPKARFFAWGLLGPDYRGPLNKKAFPGNCYPD
                     VRKYAGSDNGSAANRPEAEKLIAAVARKYKVSLFDALHPLSDHPEWYVDGLHPTEQGAR
                     RIAEITFAKLAKSLKIKQPVPRLEPGTGNVIINNPGNSGILLDGWKLTDGSNTLIFENS
                     TVIHPKDRLIIAIGPETQKDPTGPLQIKSAKSPAAFRLIPAKKY"
ORIGIN
        1 gattgtccga tccgcggcct ttttcgtccg gctctctttc aaatgcggag tttgggcttg
       61 atgaacgaaa cttcttactg tagcaacaag acatgcgttt attcgccctt cttgcaggat
      121 tctccctttg cctgagctcc acaagctgcc aatcgtacgg ggattcaagt gactacatcc
      181 ccctcgcaac gcccgttccc ccacaactct cccagccggt ttcccatgcc ctcccccgac
      241 cggccaattt ccccacacgt cccgtagcca tcccctcaag cgccccgcgc acgccccgct
      301 gcgccagtgc ctgcgttatg gacgccctta ccggcaacgt gctcttttcc cacaacggcc
      361 tccagcgccg ccaggtagcc agcacgcaga aactcgtgac ggccatggtc gtgatgggac
      421 acggcagtct ggacaaaaaa gtggtcatcc agccttccga taccaaggcg gaccccacca
      481 aactgggatt ccgggcgggg gaagtctatt cacgccgcga actgctcaat gccatgatga
      541 tccgcagttt caacgacgta gccctggctc tggcccgcga tacggctggt tccgttcccc
      601 gtttcgccca gttgatgaat gccaaagccc ggcagatggg catgtacaac tcacgcttcg
      661 ccaatcccaa cggcctcccg gcggatcaat attccactgc cattgacatg gcccgctgcg
      721 cctattacgt gtaccgcaac ccggaactgc gcaatattat ctgcaaacgc caatatgcct
      781 ttacccgcgc caacggcaga acgcttctgc tgagaaacac caacaagctg ctcacccaga
      841 acccctgggt taccggaatg aaaaccggat acacgaacgc cgccggacgc tgcctggttt
      901 cctcagccgg cgtcaacggg cgccatgtca tcgtcgtcgt cctcggctgc catccgtccc
      961 gtatctggac ggaatcggaa aacctgatca gatgggctct gggaaccgcc gcataaatgc
     1021 ccgtcggcaa ttggtatttg actttcacgg cgtgacccgc tatcagtcct gcctatgtta
     1081 caggcaggta ttgtaggtct ccccaacgtc ggcaaatcca ctctattcaa tgcggtcacc
     1141 cggacgcgca aggcccaggc ggccaactat cccttctgca ccattgaccc gaacgtgggt
     1201 atggtaacag tcccggatcc ccgcctgcag gttctttccg acatgtccgg ttctgaaaaa
     1261 atcatcccca cgcttattga attcgtggat attgccggtc tggtcaaggg agcctcggaa
     1321 ggagccggcc tgggcaacca gtttctggcg aacatccgtg aagtggatgc catcgtgcag
     1381 gtagtccgct gctttgacaa tgatgatatc attcacgaac tcggttccgt ggatcctctg
     1441 cgcgacattg acatcatcaa ctcggaactc attctggcgg atatcgccac catggaaaag
     1501 agactctctt cccgagaacg caaggcacgc agcggcgaca aggaagccaa ggccgaagtg
     1561 gccctcatca ccaaactcct gccccacctg aacgaaggca atccggccct cacccttgaa
     1621 ccgcagctgg acgacgatga acgcaagctg ctccattcct tccagctgct ttcggataaa
     1681 aaaagcattt tcgcctgcaa tgtcaatgaa gacgaactgg cggacgccat ctccaacccg
     1741 gacgcccatc cctacgtctc ccaggtgaaa aaatacgtag cggaacacca taacgcggaa
     1801 gccattgtca tctccgcccg gattgaagag gaactcatcg acgtctcgga ggaagaatcc
     1861 cgcgaattcc tggaatccct gggtgtgaag gactccggcg tttccgacct tatccgcgcc
     1921 gtgtaccacc ttctgggcct gcgcacctac cttaccacgg gaatcaagga aacgcgggcc
     1981 tggaccattc cgtccggggc aaaagcacct caggcggccg gcgttatcca cacggacttt
     2041 gaacgcggtt ttatcgccgc ggaggtagtg cactacgacg acctggtttc ctgcggcggc
     2101 aaggccggag cgagggaaca cggcaagctg cgcatcgaag gaaaagaata tgtcgtcaaa
     2161 gacggggacg tcatcgaatt ccgcttcaat gtctagacgg aagcgttacc ggaattccat
     2221 tgacttttac tgatataagg ggcagattgc tcacaacctt cacatcgcct catgactgat
     2281 acagacgtca aatccacccc cctggcagct aaacacgttg aactgggagc cagaatggtt
     2341 cctttcgccg gctggaatat gccggtgcag tacaccggca ttctggacga acacaaagca
     2401 gtgcgcgaaa cctgcggcat ctttgacatc tcccacatgg ggcagttcac ggtagccggc
     2461 ggttccgctg cggcatggct gaactccatg ctgaccaatg acatcaacaa actgaatgta
     2521 gggcaggggc aatactccgt catgctcaat gacagggccg gagtcattga cgacctcatt
     2581 ctgtaccgga tggaaccgga aaccttcttc gtagtggtga atgcctccaa gattgatgaa
     2641 gacttcgcat ggctttccgc ccatcaacct gcaggcgtaa ccctggaaaa ccactccgac
     2701 gaatacgtgg ggctggctgt tcaaggtccc gaatgcggaa aagtattctc ccgcgtcatc
     2761 cccggcgtgg aacttccccc ccgcaatgga atctcccgca tcacggcgga agggacggat
     2821 ctcattatct gccgcaccgg ctataccggg gaagatggtt ttgaattctt ctgcccggct
     2881 aaggaaggcg tcaaatggtt tgaagccttt cttggagcag gagccaaacc ctgcggcctg
     2941 ggcgcccgcg acagcctgcg tctggaaatg tgctatcctc tgaacggctc cgacctctct
     3001 ccggacaaaa cgcctctgga agccgggctc ggattcttct gcgcgctgga tacggacttc
     3061 atcggttccg atattctccg ggaacaaaaa gccaacggcc tcagccgtcg gctggccgct
     3121 attgaataca ccggcaaggg agctcctccc cgcgcccact atgccgtgca cgtccccggc
     3181 ggagaagcca tcggagaact taccagcggc gtgctctctc cttcgctgat gaagggcatt
     3241 gccctggcct acctgcctgc cgcccatgcc aaggtcggca cggagctgga aattgacgta
     3301 aggggaagga aattcccagc cgtggtcgta aaaaaaccct tttataaaaa aggctgacac
     3361 tacggcgcaa aaataaactg acaaacccct cattttacta cactctcact tcaaacaatt
     3421 acatcttatg cacgacgtac cagaaaatct gctgtattcc aaagatcacg aatggattga
     3481 aattgacggg gacatcggca ccatcggcat ttccgaccat gcccaggccg aactctccga
     3541 tgtcgtcttt gtagaccttc ccgaagtagg cgccaccgtc gcagctggcg accctgtcgc
     3601 tgtcgtggaa tctgtcaaag ccgccagcga cgtgtacacc cccgtttcag gagaaatcct
     3661 ggaagtgaac gaagagcttt ccaatgatcc gtccctcatt aactccgacc cctacggcgc
     3721 aggctggctg tacaaaatcc gcctggacgt tcccacggaa acggaagata tgatgaacgc
     3781 cacggattac gaggaatact gctcctgaac cattcttccc tcccccgccc cggtgattcc
     3841 atcccggggc attttgtttg gcccgttccg cggtcggacg ctattaccag ccagagatac
     3901 cacatgaata cccactcaga ttttgccagc cggcacatcg gcccccaggg ggaagaacgc
     3961 cgggaaatgc ttgacagcct cggctaccgg acgcttgacg aactcattgc ggacatcgtc
     4021 cccgcagata tccgcatgaa ggccccgctg gacctgcccg cagccaaatc ggaaacggaa
     4081 gccctgaagg aactccgttc cattctgcgg aaaaacaagc tcctaaaaac cttcattggc
     4141 cagggctatt acggcaccat cactccctcc gtcatcctcc gcaatgtact ggagaacccc
     4201 ggctggtaca cggcctacac cccttatcaa ccggaaatcg cccagggacg gctggaaatg
     4261 ctcatgaatt tccagaccat ggtctcttcc ctgacagggc tgccggtagc gaacgcctcc
     4321 ctgctggatg aaggcaccgc agcagcagaa gcagtcacca tgtgccggaa tgcgcgcccc
     4381 aaagcaaaca ccttctttgt ggcggacacc tgccaccccc agaccatcag cgtcatccgt
     4441 acccgcgccg ccttccaggg cgttaacatc atcgtgggag attgctcctc ctttgacccc
     4501 gcatccatcg gtgcggatct ggccggagtg cttgtccaat atccggacac gctcggctgc
     4561 atctgcgact acacggactt cttttcccgc gtgcatgcca cgggcgcgct ctgcgtcgtg
     4621 gcggcggatc tcatggccct taccgtcatc cgggaacccg gcgccttcgg agccgatatc
     4681 tgcatcggca acacgcagcg cttcggcgtc ccaatgggct tcggcggccc ccatgccgcc
     4741 tatatgtcct gcacggacgc tctcaaacgc cgcatgcccg gccgccttat cggcatgtcc
     4801 atagataccc tgggccgccc ggcctaccgc ctggccctgc aaacgaggga acagcatatt
     4861 cgccgcgaca aggcgacctc caacatatgc accgcccaag tgctcctggc cgtgcttgcc
     4921 gccttttaca ccgtatacca cggccaggaa ggcctcaaac gcatcggcac ggaaatccac
     4981 ttgaaaacca aaagcctgta caaggcgctc acggaagccg gcattgccat tgaaaacaaa
     5041 aacttctttg acaccctgct gctgtccgtt cccggacaag cggacgctat ggtgcaaaaa
     5101 gccctggaag ccgggtataa catccgcagg gtggatgccg accacgcagc catctctctg
     5161 gatgaaaccg caacctgtgc ggatatagcg gcactggcct ccgcccttgc aggtgcggaa
     5221 acatccgcca cctgcgattg cgacgctcct gcctgggatc ccgtccacac gcgccagacg
     5281 cctttctgca cggaaaaggc tttcaactcc taccattccg aaacggaaat gatgcgctac
     5341 atccgccgcc tggaatcccg ggacctggct ctaaatgaag ccatgatccc tctgggctcc
     5401 tgcacgatga agctgaacgc cgcctctgaa atgattccca tcacgtggcc ggaagccaac
     5461 tccctgcatc cctttgttcc ggcggaccag tcggaaggca tccgggaaat gctctccgtc
     5521 ctgtccgacc gtctggcgaa aatcaccggc tttgccgccg tttccctcca gcccaacgcg
     5581 ggcgccgcag gggaatatgc cgggctactg gccatccgcc gctaccagaa gcacgccgga
     5641 gaaggccacc gcaatgtctg cctcattccc acctccgccc acggaacaaa tcccgcctcc
     5701 tctgccatgg ccggcctcaa ggtggtaccc gtcaaatgcg acgaaagagg caacatcaac
     5761 atggcagacc tgaaatccca ggcggaagcc cataaggaca atctctcctg catcatggtc
     5821 acgtacccct ccacgcacgg ggtatatgaa cagacaatca aggaactctg cgacatcgtc
     5881 catgccaatg gcggccaggt gtacatggac ggcgccaaca tgaatgccca ggtaggtctg
     5941 acttgccccg gctgcattgg cgcggacgtc tgccacctga acctgcataa aacctttgcc
     6001 atgccgcacg gcggcggcgg tcccggcatc gggcccatcg gcgtagcgga acacctcgta
     6061 cccttcctgc ccgggcacct cacgctgggc catgaagaag gggccgtagc gtctgcggcg
     6121 tggggaagcg cctccatcgc cgccatctgc tggatgtacc tctccatgat ggggccggac
     6181 ggcctcaggg aagccacgga aatggccatc cttaacgcca actacattgc caagaaactc
     6241 ggacatctct tcccggttct ctactccggc aacaaggggt tggtggcgca tgaatgcatt
     6301 ctggatccgc gtcagctcac tcatgacgcc ggcctcacgg tggatgacat tgccaaaagg
     6361 ctcatggact acggcttcca cggccccacc atgtccttcc ccgttccggg caccctgatg
     6421 gtggagccga cggaatcgga acccaaaaaa gaactggacc gcttcattga agccatggaa
     6481 cgcattcatg cggaaatcac ggccattatc aacggtacgg cagacaagga agacaacgtc
     6541 ctgaaaaact cgccccatac cgcagaaatg gtctctgccg acgaatggcg gcatccctac
     6601 tcccgcagtg aagcggctta tccggtctcc ggtctcctta ttcacaaatt ctggccgtat
     6661 gtaggccggg tggataatgt gtacggagac cgcaatctgg tctgcacctg cgacacggtg
     6721 gaggaattct ccaaggccgt agagttataa aaatctcatc cttcctttca aaaaggctgt
     6781 tccattcatt tggagcagcc tttttcttat gttcaagaat cggatttcta atccgaagtc
     6841 aacactctat tttgagtaca aatgggtcat caaaatgaaa ggggaggaaa agcagggtag
     6901 gagaaatgtg cctttttctt ttttaataca tactgctttt atgcttaatt gttttctgga
     6961 tgcgtttgtt tcttcggatt agaaatccgt tgagctacgt ctcagatgag ctttttctct
     7021 gcccttactg ttcctggcct tcaacagcat ctttcttttt ccagggaaga ttccgctatc
     7081 ctcaaagggt atggaattct cttcatgatc tttcatcatg tcttcggctt atacgctcta
     7141 cccgcaggtg tggatacggc atggattgct ccccagctta ccaaagccgc tcccatcttt
     7201 aaaatttgcg tgcccatttt tattttcatc acggggtacg ctatgggatg gaaaacaaat
     7261 tcatccccaa ccttcggttc cctcattaaa acaggctttt cccattactt taaattctgg
     7321 aaaatttatt tcttatgcct ccttctggct attctggttt cctgggcatt ccccttgccc
     7381 attttgccat ccgttgccga catgggttgg aaaaatggcc tgcttgtcgt aacaggattg
     7441 aggccctgtt atcccgactg gtggtacatg gctcttttcg cggcagccac catggccctt
     7501 tatccaatct gtgcgtggat cacgcatcac attgcgcctg tcccgtccat ggcagctctg
     7561 ctgggagtgt cccttttatt tcaaagtacg gcccacattc ccagcctgcc gggaatcgcc
     7621 tattccttcc ctcctttcct gccctgcttc attctcggct acatgtgcgc ctttctggct
     7681 tcacgcctct ctgctctttc aatttcccaa agcttgggag caatcctgtt gctggctctt
     7741 gaaatactat ccatccatct cttcagtttt tcaaaagcca aaaccctgac ggttatcttt
     7801 ctcttcaccc tctggtgtct gccttggata acccggaaac tccgcctcac accgctcttg
     7861 acgctgctgg gaacttattc cgcacttatg tggctgaatc acagattcat tttcggctac
     7921 cacttcagct gggacctcta tggaacccaa agcatcagcg tagtattcat cgtgacgctg
     7981 gtctcttccc ttctgctggc catggccatg caaaaacttt ttaaccggat gattccctca
     8041 aatccgcaaa cacagtcaaa aactttgtag caactttaca aggtccggat tccaacacct
     8101 cttaattcca agggggatct ccgtacttat tttctccaat ccggctttcc ccatgggata
     8161 aataccacaa cagcagccac cctatgaagg gaacggccag aaaaaccagg aaaaagccgc
     8221 tcctcccgac atcatgcaga cgccggacca tggtagccgc cagcggaata gacagcacgg
     8281 cgagcaccac gtacagcaga ggggaaacca gctcaaccca cggaaccagg gacgggaaca
     8341 aaccgcattc cgcaaaagag gggactcccg ccacggccag ccacgcaacc cccactctgg
     8401 aaaaaacctc gtgcaactcc cctttcccgg cacggccctc aaaacggcac catgccttga
     8461 tgacgcgtat ccagtacttc ttcctgctcc agccggagtc ggtgcctcca ggctctgaac
     8521 cgggatccgg cagaacggag ggctccccat catcatccat aacagtcatg gaggggataa
     8581 aagaggccag aggcctccag tctccgccgg gaaccttccg gaccaaagtc cggttggaca
     8641 ggcggccgag gttacgggcc cgcagcaaaa gcaccaggtc aaccgggcct ttggaagaac
     8701 cgtcaattgc ctgatactcg tacagatcgc tcatggggac gcttacctgg attccttccc
     8761 gtggctgaag gcggaggcgg gaatctcctg cttggacaaa ccgggacctt cccacttcaa
     8821 aaccagtttg gaggcagtac cggagttccc cacatagccg atgcggatgg gatgaagtcc
     8881 ggctttcaaa taaacgggat tcttccggtc acccagatcg gaggagacct cggcccccgg
     8941 ctcataagtt ttgtccgcgt caatcaattc catgccgtgc agacggacaa aagccttgct
     9001 gcccttattt tcatccgtgg tcagataaaa cgtatatgct ccgtcctctg gaatcttcac
     9061 atatcccgtc agctccacac cgcgcttgtc cgaaccgttc attttcacgg atggggaagg
     9121 cgtcacgcca tgggcggaag caggcttctt ccactggcgg aaatccggta cccagggaaa
     9181 atccccctca tacaaggccc atcgcaaccc gggagaaacg gttcccttca catccacggc
     9241 aggcaccagc gcagaatcaa acactgtttt ggaaggaagg gaagcccggc gattggacaa
     9301 agcggcggct ttcatgcggg cctgaagttc cggcttggag gatgcgagat ctttgctttc
     9361 ctgcggatca ttcaaagtat caaaaatcat gaaatccttg tccgcatcct tcacccccat
     9421 gcgcaagcct ttcaatccat ccacaaaaac aatctgctgc tggcctcgct gcgctccctt
     9481 gtgttcgccc aggaaatcct tatactccgg cgttttgccg gcgaaattat attcggcata
     9541 aacaatgccg ggcttctgct ggtccgcatg accggtcagc gtcggcagca gggaaacgcc
     9601 gtcactgcgg gctggaaccg gcaccccggc gacatccgcc agcgtagcca gccagtcatg
     9661 gaactgtcca ggatgcaggc tgatctgccc tttgggaatg cgggcgggcc agcgtaccag
     9721 cgtaggcacg cgcatgcctc cttcccagca atcgcgctta ataccgtcca tcatgccata
     9781 actcttgaaa aactgcggat tttgcgctcc gtgccagtgc ctggggtcgg agccgccctc
     9841 attgtggggg ccattgtcgg acgtgaagac gatcatcgta ttatcgtcaa tcttcaaatc
     9901 tttcagcaga cggatcaaat cagccacggc atcgtccacg cggcggatca tggtggaatg
     9961 acgtttggcc acatcattcg ggaaacggga attgtccgga tgaatatagg tatccttatt
    10021 cttttccgcc ctggcgtcaa aagccgtatt cacggattcc gtgccttcct tctttaccca
    10081 ttgcaggcct cctttcaatc cgccgccgga aggataggga acccccggaa ccaccagatt
    10141 gccgtggggc gccggaaaag ccaggtacag gaaaaacggc tttccggtct tgcgggcgga
    10201 cttgcgctgg tccacaatcc actgcttggc gcgggcggca aataaatccg tggaataagc
    10261 cgtctggggc acctggtcct tgatattttt ccactcggga ttggaagcgt aaccgttgta
    10321 ttcgaaaacg tcacgggatt cggaaggata gtgaaaatgc cctgccaaat ggtccaggat
    10381 accgtaaaaa taattgaatc cccgctgatg ggggccggcg gtcatgggca catggctctg
    10441 gcctccgccg cccacacccc atttgccaat ggcagcagta tcatacccgg catcacgcat
    10501 cacggtaccc agcgtatggg aatcttcaat aggctggtcg aaacggttgt ttctcaccac
    10561 gcgggaattc ccctggtgca cccctagcag cagggaggcg cgcgccggag cgcaaaccgg
    10621 agcggcggaa taatgacggc gcagctgaat cccctcccga gccagagcgg acagggcagg
    10681 agtcttgaac tcgttctttc tctccaccgt ccggccattc agcttctgct ggctccagtt
    10741 ggaatccaga tcaccccagc ccatgtcgtc caccagaatg aaaataacat tgggttttga
    10801 agttttgaca gaccgggcag ccggcttcgt tgcctgcccg gaagcaccca tgcacggaac
    10861 cagggaagtc agaagaacgg atagtaaaga taccagcttc atgattcaaa gaaaatagac
    10921 tctaaaaaag acgttaaaat aaagcgttat cttacatgaa ttttctcatc cctcaagaaa
    10981 attacgagga aagggcacag aggattgaat cgccagtatt atcggcaaaa aacatcaggg
    11041 aaccagcctt cacagccgga acaactacaa cccgccatac tgcaccaatg agcggctttt
    11101 ctggctgaag ccaggaatgg gagaaaattc ctcctgcatt cccggcgccc cggtcaccag
    11161 ccccgcccgg ccatgcttta tcctgaataa aacggcagtc cccccgccgg gcagaaaata
    11221 cagaaaccgg cggaaacagc aatcatgaac cggaacgttc caaaatgtcc gcgccaattc
    11281 cggaacagcg ttaataaccc tgtccggaat agcgaaggca tcagaaacgc ttcttcctgt
    11341 cgtccctgcg ggaacgttcg ccccagcgtt cgccgcggtc actgcggaag cccccgcggt
    11401 ttcccctgaa tccgctccgg tcactgcggt cccgctctcc gcggtaactg ttgcggaatc
    11461 ctccattgcg gcgggaagag cgcggagttc cggaatattc cggagccccc ttgtcttcac
    11521 ggacattaac ttcatagccg cagacggtag ccgtcgccag ggcctccaga agcaggggcg
    11581 ccacggaagc gtccacttct atcagggaat gcttggggaa aatccggata tcgcccacgg
    11641 ctcccttttc catttccacc gtattgtaaa ataacccggc tatgtctttg ggccgcaagc
    11701 caatcatccg gcctccattc ataaacagcg taaccgtatc ccccttatgc tgccaggaat
    11761 cacccttctg cgggctctcc gcctcctccc cggtctgcgg catacgccgc gccctgcggg
    11821 cgggcttgtc ttccggaatg ggctgcactt cccggtgcgt acgttcccgg agcaagtcaa
    11881 acagggccgc agccatggcc tccggcgcag cctccacttc cttcaattcc tccggcagca
    11941 cggcatccgg cttgagacgt tccaggatat catccaccag ggactctgtc cggagctggt
    12001 ccacctgaac ggcagtcaac acaggttccg gagtcaactt aacgccgatg aaacgttcaa
    12061 tgcggctcat cagggaaaaa tcacggcgcc ccacaaaagt gatggccttc cccttgcggc
    12121 cggcgcgtgc cgtgcggccg atgcggtgca cgtaatcctc cggatcacgc ggcaattcaa
    12181 aattcaccac ggcatccaca tcgtccacat ccaggccgcg agcggcaata tccgtcgcca
    12241 ccagaaggcg caggctcccc ttgcggaagg aatccatcac gcgctccctc atcatctggg
    12301 gcatatcccc atgaaggcga tccaccggat aaccgcgggc cgtcagaccg tccaccacgt
    12361 catccaccac ctttttggta ttggcgaaca ccagccccat tttaatcttt ccggtgtcaa
    12421 gcagccggct gagtacctca atccgggagg aaaacaccac ttcgtaataa acctgttcaa
    12481 tggtaggcac cgtcagcgta ggccgttcaa tggaaatctg gacgggctcc ttcatgaacc
    12541 tgctcaccag gcggctgatt tccggagaca tggtagcgga gaaaaacagg gtctgcttcg
    12601 cttccggcat agcgtccgcg atatgttcga tatcttccag aaaccccata tccagcatct
    12661 cgtccgcttc atccagaatc aacatgcgga gaccatccag ccttagcgcc ccggactcca
    12721 tcaggtccat gacgcgtccg ggcgttccca ccacaaactg taccccgcgc ctcagggcgt
    12781 ccagttgcgg acggaaagaa gagcctccgt aaatggggac ggcggaaaca ccgtccatga
    12841 acaaagccag cttgtccacc tcccggcaaa tctgaacggc cagttcccga gtaggacaga
    12901 gggccagcac ctgaacgcag cgttcctcag gatcaatgca ctccagggcc ggaatggcaa
    12961 aggcaagcgt cttcccggag cccgtatggg acaaccccac aatatcggcc cctccgatcg
    13021 cggcgggaat cgcctgctcc tgaatggagg aaggggtatc gaagccgagc acttcgatag
    13081 cctccagaat ctccggtgaa ataccaagag ccgaaaaaga agatgtttga gtcatggggg
    13141 aaaaatgatc tgtcagagtc acgggagaag ctgaacatta ttccctcccg tgtccagcca
    13201 aaagaacgga agataccgta gatgccacga tttccgcaaa gccgcctgcg aataaaaaaa
    13261 acggatctcc ccgcttctgg tctttactgt cacacacggg gttgcaactt gcaggggcgc
    13321 attcgcgtat gatacaaata tttccctccg aattcatgga taaaacgcca aacaaatcac
    13381 agtcctccct gctgggaatt ttcatcaaca tcctcctccc ggtactgatt ctggactact
    13441 gcagcgcggg ccccgccaat cccctggaac gtccggaggg agaaagtttc tggcacatcg
    13501 gcccggtatg gtccctcgtc atcgcccttt ccctccccct cgtctacggc atccgttccc
    13561 tggccgtctc caggaaattt gacctgatgt ccgtcgtagg catggccggc gtgctgctga
    13621 cgggcgtcat cagcatcttc gtcatcgggc cggaagggcg catccacagc gccacaccct
    13681 ggctgttcgc cggaaaagaa gccctgatcc ccctcatcct ggcggcagcc gtcgtcgtct
    13741 cccgctccac cggcaccccc ctcctcaaca tgttcatcta cacgccggag ttattcgacg
    13801 tgcgcaggat agaacaaacg gtggccgcca acggcgagga acaggcctac cagagcctgc
    13861 tggcaaactc gtcatggatt ctggcgggca cattggtcgc atcctccgtc ggcaatttct
    13921 tcctgagcct ctctttcatg tcctccgtca tacgccagcc ggaagcggaa cagcaagtgg
    13981 cctacaatgc cgctatcggc agcatcacct ggtggggctt cctgatcatc gggatcccca
    14041 ttctggcagc tcttgtcttc atcatgaccc gcctgattaa acagctcggc aggctgaccg
    14101 ggctctcacg ggacgaactc cttctcaaat aatcctcaaa ccatgcgcct ccatacttca
    14161 tgcatcctgg ctgccgccat cgcccttaac gcagcgtggg cggacgcccc ccggttcgac
    14221 cggattttcg gttcccatat ggtacttccc cacggaaaaa acattcccgt ttccggcacg
    14281 gccgccccca acagggaaat aaccgtcact tttggaaaca ctgctctgaa aacaaaaacc
    14341 gattccaaag gaaaatggag cgtcacgctg cctcccatgc ctccctgcgg cacaggccag
    14401 acgctggcgg ccgtgcaaaa cggagactcc gccaaattgg aagatgtgct cgtgggggaa
    14461 gtgtggctgg cttccggcca atccaacatg ctgttccgcc tgaaccagac cacgacggcc
    14521 aaagaagaca tagcggcttc cggagatgac cagctccgcc tactcaacaa tattccgcaa
    14581 gcccacacca acaacgcccc ctactccggg aaagattttg acgccgtcac cacggacaac
    14641 ttctataaag ggcaatgggc ctccagctca ccctccactt caggccccat gactgccgtg
    14701 ggctactatt tcggaaaaaa actccgcgaa gggctgggca ttccggtagg catcattcac
    14761 tcctccctag ggggctcgga aatcgcagcg tggctcccca gggaagtcat taatgcaaac
    14821 aacagtttcc gcaccctgcg cggcaaccac tggctggact ccccccttat ctccgactgg
    14881 gtaaggggac gggccagaaa aaatatctct ccgcgtctga atcagggatc tccggaccat
    14941 ccctacaagc cggcgttcct ttacgaatcc ggcattgcct ggacaacacc actccccatc
    15001 acaggcgtga tctggtatca gggcgaatcc gatgcggaaa ttattgacaa cgcccaaaac
    15061 ggcatgctgc tgaaaaccat gatctcctcc tggagaaaag ctttccgcaa cccggaaatg
    15121 cccttcgtca tgatccagct cccccgcatt aacgatccgt caaaaatccg tgccggatgg
    15181 ccggaattcc gcgaaatgca ggacacagtg gccaaaaccg tcccgcaggt ttacagcgtc
    15241 aacaccattg atcttggctc caccaatgcc gacgttcatc ctccgttcaa gcgccctgtt
    15301 ggggaacgtg caggaaatac tgccctgaac aaggtttacg gtaaaaaggt cccctgtgaa
    15361 ggccctgcct tcaaggcctt caagacctcc ggttccagca tcctggtcca gatggaacaa
    15421 gctgccggac tgaccaccac ggacggcaag aaaccggccc agtttgaaat tgccgggacg
    15481 gacggaattt accatcccgc cacggcggaa atcacaaaca ggaaaggcgg cacagccgtt
    15541 atccgcctct cctccccgga agtaaaatcc cccaaaaacg cccggtattg ctggaaccgt
    15601 ttcgtgaccc ccaacctggt caacggcaac cagctccctg cccgtccctt ccggacggac
    15661 gtacccgttc tgaaaaaata actcttacca cgccatcatt ccatgaacct tcatcttttc
    15721 cttgcttccc tggcagccac gctctcactg ggcattgcgg cacaagcttc tcccgccaaa
    15781 gtggcctgcg taggggacag catcaccttc ggctccggcc ttaaacccgg agaagcccgg
    15841 tatccgcaag tgctcgccac gctaatgggc ccggactttg acgtcagagg attcggcaat
    15901 cccggaaaaa cggcgggcga ctatccgggc caagcaggac gctggtacgg cagcaccagg
    15961 gaacacaagc aagccctgga cttcaaggcg gatatttata tttgcaacct tggcattaac
    16021 gacacaggcc gatggtggaa ccccgaacta ttctccaaag gctatgaagc gctgctccag
    16081 gcatggaaaa acgccaatcc caaagcacgg ttctttgcct ggggcctgct ggggccggac
    16141 taccgcggcc cgctcaacaa aaaggcattc cccggcaact gctatccgga cgtacgcaaa
    16201 tatgcaggct cggacaacgg ctccgccgcc aaccgtccgg aagcggaaaa actgattgcc
    16261 gccgtagcac gcaagtacaa agtcagtctc tttgatgcgc tgcacccgct ctccgaccat
    16321 ccggaatggt atgttgacgg gctgcatcct acggaacagg gcgcacggcg tattgcggaa
    16381 atcaccttcg ccaagctggc aaaaagcctc aagattaagc agcccgtccc caggctggaa
    16441 ccgggtaccg gcaacgtgat catcaacaac cccggtaatt ccggcattct tctggacgga
    16501 tggaaattga cggacggctc caatacgctc atttttgaaa attccaccgt catccatccc
    16561 aaggacaggc ttatcatcgc cattggcccg gagacccaaa aagacccgac cgggcccctg
    16621 caaatcaaat ccgccaaatc ccccgcagct ttccgcctca ttcccgcaaa aaaatattaa
    16681 aaaccactgg aacagtttca ttgggaacat acggaactgt tgcatgttcc caaatacccg
    16741 gcgcactcta
//
