LOCUS       c00005_gnlPro..        14552 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ICGLFAJH_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 10:23:41
            Original ID  :: gnl|Prokka|ICGLFAJH_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14552
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14552
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1708:4552]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1709..4552
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..14552
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14552
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             2..712
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_1"
                     /sec_met_domain="Transket_pyr (E-value: 2.1e-18, bitscore:
                     59.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FVFSDYMKPAVRMAALMEVPVKFIWTHDAFRVGEDGPTHEPVEQE
                     AQIRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMENTTTPTGLIFSRQNIANLPEG
                     NDYEQAAKGAYIVAGSDENPNIILVASGSEVATLVAGTELLRKDGIKVRIVSVPSEGLF
                     RSQAPGYQEGIIPCGAKVFGLTAGLPVTLQGLVGPRGKVWGLESFGFSAPYKVLDEKLG
                     FTAENVYKQVKAML"
     CDS             804..1241
                     /locus_tag="ctg5_2"
                     /transl_table=11
                     /translation="MKTIGICSDHAGFELKEYVRGWLEAKGWAYKDFGTYSTESCDYPD
                     FAHPLALAVEAGECYPGIAICGSGEGISITLNKHQGIRAALCWTAEIAHLARQHNDANV
                     LVMPGRFISTEEADMIMREFFSTPFEGGRHQRRVDKIPVHL"
     CDS             1417..1692
                     /locus_tag="ctg5_3"
                     /transl_table=11
                     /translation="MERLNTIKELINQGNVEQAIQQLDEILQTDFPGKDEAYYLRGNAY
                     RKQGNWQQALNNYQYAIDLNPESPAQHAYQMAMDILNFYNKDMYNQ"
     CDS             1709..1936
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_4"
                     /sec_met_domain="Fer4_7 (E-value: 8.3e-13, bitscore: 41.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.9e-08, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.2e-08, bitscore: 25.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.3e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLNVIALTKEVNVKGYNYAH
                     QILEDTCNGCASCATVCPDGCISVYKIKVE"
     CDS             1956..3041
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_5"
                     /sec_met_domain="PFOR_II (E-value: 3.2e-28, bitscore: 90.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.1e-48, bitscore: 158.3,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKMVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVGLAFELAFK
                     YRNPAIILADGVIGQMMEKVVLPVQKPRRTDAEVIEQCPWATTGRTNGRKPNVITSLEL
                     KPEEMEKNNIRFQAKYKQIEENEVRFEEIHCDDADYLIVAFGSMARIGQKAMELAREEG
                     IKVGMLRPITLWPFPTKAIAAYADKVKGMLVTELNAGQMVEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVDALKEKLIKK"
     CDS             3038..3211
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMVLALAAIIIYFAAKDDFKLFIYVCGAAIFV
                     KLMEFFIRFTNR"
     CDS             3223..3984
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.3e-26, bitscore:
                     83.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEDIIKPENLVAKKPTLMNDNPMHYCPGCSHGVVHKLVAEVIE
                     EMGLEDKAIGISPVGCAVFIYNYIDIDWQEAAHGRAPALATAIKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKTSTSPYGRDVHLH
                     GYPLKMADIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMAGKGSNLVEIVSTC
                     NSGWKMSPAKSNEWMVENMFPFYPLGDLKDK"
     CDS             4007..4552
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_8"
                     /sec_met_domain="POR (E-value: 7.1e-36, bitscore: 116.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDEKISSPILSKYDAAIILNQPSLEKFESKVKPGGVLIYDGYGIINPPTR
                     KDIHVYRINAMDAANEMNNAKAFNMIVLGGLLKIKPMVTLDSVLRGLKKTLPERHHHLI
                     PMNEEAIKKGMELIQEMK"
     CDS             4638..4913
                     /locus_tag="ctg5_9"
                     /transl_table=11
                     /translation="LIYCKGLFHFKPEKVWIQGQRTGSSIEQNRKQDSLKEAKKAEFSK
                     QIIFYCIFAPNYETNCTDIYISVRYRDMGGYGAKHLKPDEQSRPVR"
     CDS             4888..7017
                     /locus_tag="ctg5_10"
                     /transl_table=11
                     /translation="MNNRDRFGNQIDPNTQPDNLEDSTNTEIQSLPPKLYMWKLSETLG
                     NRTIIPADTASLNFQSTNLVEGMFGHYNYLGNLGSPRLSRLFFEREESEPTIFMAPFSS
                     FFTRPDQVLFTNSNVPYTNLTYYKAGNKVNGEERFKSYFSVNVNKQLAFGFNIDYLYGR
                     GYYQNQSTSHFNAGLFGSYIGEKYQVQAVYNNFFLKMNENGGIADDQYITRPENMSGGK
                     KEYESTTIPVKLEQSSNRNKDFYIYLTQRYRLGFTRRVRNTQEGKPTVSAPKASSSPSS
                     ESEISASNNDIALPNDSIASKSVSTLAAANDSLPSVSTADNDSLFEEEFVPVTSFIHTL
                     KVERSRHQFRSGSEPEGFFPEDYKLYKNYSNDSTTAFSVKNVFGIALLEGFNKYAKAGL
                     TAYISHKFSRYDLMNTDTLTDMRRIRYTEQEIFVGGELAKREGKLLHYNVNGEVGLVDK
                     AIGQFRVNANLDLNFRLWKDTVNFYARGYVSNTLPSFYMRHYHSNHYNWDNDNMDKEFR
                     TRVEGELNISHWGTNLRAGVENIKNYTYFNQSALPEQNGGNIQVLSATLKQDFRLGVFH
                     LDNEVTWQKTSNETVLPLPQLSLYHNFYILAKLAKKVLTVQLGADVRYFTKYNAPAYAP
                     GVQQFHLQPTDDLVEIGGYPIVNVYANLHLKRTRIFAMMYHVNAGMGSANSFLVPHYPI
                     NPRLFKIGVSWNFYD"
     CDS             7029..7859
                     /locus_tag="ctg5_11"
                     /transl_table=11
                     /translation="MTKSRLLKYALLGIAAALIAHYLIKKEEKPKGHPRDYAEITAEGI
                     IHASTEYNSISFYVDDDTLSGFHYKLIEAFARDHGLQAAISPEMSFNKRLEGLADGQYD
                     VIAYGILATSELKDSLLLTTPIVLNKQVLVQRKLENISDSSLFIKSQLDLAGKTLHVVK
                     GSPSILRIRNLGNEIGDTIYVEEIEKYGSEQLIALVAHGDIDYAVCDESIARTAADSIP
                     QIDINTAISFTQFYSWGVSKQSPILLDSLNTWLDSFKKGKEYKKIYKRYYGKRN"
     CDS             complement(8088..10013)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_12"
                     /sec_met_domain="CN_hydrolase (E-value: 1.1e-19, bitscore:
                     63.1, seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_synthase (E-value: 2.9e-32, bitscore:
                     104.1, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYGYVKVAAAVPRVKVADCKFNASEIEKEIIIADGKGVQIIAFP
                     ELCITGYTCGDLFAQQLLLEEAEMGLIQILNNTRQMDIISILGMPVALNGVLLNAAVVI
                     QKGRVLGVVPKTYLPNYKEFYEKRWFTSACDVAENSVRLCGQIIPMGRDLLFETADTTF
                     GVEICEDLWAPIPPSSTLALQGAEILFNLSADNEGIGKHNYLRSLISQQSARCIAGYVF
                     SSCGFGESTTDVVFAGNGLIYENGTLLAANERFSFEGQVVISEIDVEHLRTERRVNTTF
                     AACHANCVSALPVRISTEYVNSRDLNLTRTFEPHPFVPQGIALDERCEEVFSIQVSGLA
                     QRLVHTKAKSAVIGISGGLDSTLALLVCVKTFDKLGWSRQGIVGVTMPGFGTTDRTYTN
                     AIDLMNSLGVTVREVSIKEACIQHFKDIDHDVHVHDVVYENAQARERTQILMDIANQTW
                     GMVIGTGDLSELALGWATYNGDHMSMYGVNASVPKTLVKHLVKWVAEHDMDDASRATLL
                     DIVDTPISPELIPADENGNIQQITEDLVGPYELHDFFLYYFLRCGFRPSKIFFLAARTF
                     KGMYDEETIKKWLQTFCRRFFNQQFKRSCLPDGPKVGSISLSPRGDWRMPSDASSEMWL
                     REVEGL"
     CDS             10310..10744
                     /locus_tag="ctg5_13"
                     /transl_table=11
                     /translation="MDVVKRLQNHNIKPSVQRIAIMNYLIEHRTHPTVDEIYTALSPSI
                     PTLSKTTVYNTLKLLSEQGAAQTLTIDERNTCYDADTSPHGHFLCKRCGKIYDLMCNNN
                     IKKVVDMDMDGHDVQEIHYYYKGICKHCIEEERLRTTKNN"
     CDS             10771..11328
                     /locus_tag="ctg5_14"
                     /transl_table=11
                     /translation="MKKFRCTVCGYVYEGDAAPEKCPLCKAPASKFVEVEEATADGPLV
                     FADEHVIGVAKGCDDEMIKDLNNHFMGECTEVGMYLAMSRQADREGYPEVAEAFKRYAW
                     EEAEHASKFAELLGDCVWDTKTNLEKRMNAESGACEDKKRIATRAKALNLDAIHDTVHE
                     MAKDEARHGKGFEGLYNRYFKK"
     CDS             11453..11977
                     /locus_tag="ctg5_15"
                     /transl_table=11
                     /translation="MELKEFKITVLPLRAKLLNYARKLTDEPEDAEDAVQEVLLKLWNK
                     RLELEQYRSIEAFAMTLTHNICIDMWRCKRNDNLSLDIVQAASPTGTPERLLEIKDEIR
                     LMHEIIHSLPNLQRTIMQMKDIEGYETDEIAEITGCGPEAIRSNLSRARKKVRDVYLRT
                     IQERKERRNEP"
     CDS             11974..12432
                     /locus_tag="ctg5_16"
                     /transl_table=11
                     /translation="MKIDELLDKYFEGETSCEEERELRRFFTEEEVPEHLQTYRPLFAY
                     LNREATSMAEPTEEKSVTTESAKEVPAQRKPFRLYRTFYAVSGIAAGLLLLLGVAKIIF
                     PLSGVPENYVVIDGQRYTDEKLVEAKALEALQNASFTDEDLSNLLFQH"
     CDS             12445..12915
                     /locus_tag="ctg5_17"
                     /transl_table=11
                     /translation="MKTSILICIRSLCLFSLLICLPAFVHAQERLQIADLFSKYGEQKD
                     VTRVELNGSILKSYRMTTYKSLVFKNVSPYRREIQQAIVHDKQDNAKKAQEVMESGVLR
                     SAYYQLKEVERNGKKLNRYIIFKIGKDSMGTLIYIEGLLSEKEMMDMLYKSE"
     CDS             12936..13841
                     /locus_tag="ctg5_18"
                     /transl_table=11
                     /translation="MKTRIMILACLLAVPAGRMAAQQQTDPEQKATVQTQGDSIIIRKG
                     KGDMRIKVYEEQLEDGEKKEVQIYEGVYLEKVDADKRTFLDALPFIPKKRRYNAYEPHC
                     SGLYIGYSRLANDFLSFGASDKMGLDLSKSWEFGFNILSVYHNFKKNPHWGINLGVSWG
                     YRSFNIDGNYALLKENGTSIFTAGNEDTSYNKSRLRHFFFRVPVLMEWQQRVGRNKVFF
                     NAGPEFEIRHSVKSFSHINGGKKKTVGKGMYVQPVGINLLAQAGYGNIGIYLRYSTYGL
                     FQKDKGPEVSPYSFGVAWYL"
ORIGIN
        1 cttcgtattc tccgactaca tgaaacctgc cgtacgtatg gcagccctga tggaagttcc
       61 cgtgaagttc atctggacac acgatgcctt ccgtgtaggt gaagacggtc ctacccatga
      121 accggtagag caggaagccc aaatccgcct gatggaaaaa ctgaaaaacc acaagggaca
      181 taattccatg ttggtactcc gcccggcaga tgcagaagaa acaactgtgg catggaaact
      241 ggcaatggaa aataccacaa ccccaaccgg tttgattttc tcccgccaga acatcgccaa
      301 cctgcccgaa ggcaacgatt acgaacaagc tgccaaaggc gcttatattg tagccggctc
      361 cgatgaaaat ccaaatataa tcctcgttgc ttcaggctcg gaagttgcca cattggtagc
      421 cggtactgaa ttgctgcgca aggatggcat caaggtgcgt atcgtgtccg ttccttccga
      481 aggtctgttc cgtagccaag ctccgggata tcaagaaggc attatcccgt gtggtgccaa
      541 ggtattcggc ctgacagccg gtctgcccgt cacactgcaa gggctggtag gtccccgcgg
      601 taaagtatgg ggattggaat cattcggatt ctcggcacct tataaagtgc tggacgaaaa
      661 gctcggtttc accgcagaga acgtttacaa acaagtaaaa gcaatgttat aatcattatc
      721 caatgtgctg atgtgctgat tgcccgcgcc ctacaagctg caggcatcag cacattggca
      781 cattggtata ttaactgacc atcatgaaaa caataggaat ctgttccgac catgcaggct
      841 tcgaattgaa ggaatatgtt cgcggctggt tggaagccaa aggctgggct tacaaggact
      901 tcgggaccta ctcaaccgag agttgcgact atcccgactt tgcacatcct ttggcactgg
      961 ccgttgaagc cggagagtgc tatccgggaa ttgccatctg cggaagcggt gaaggtatca
     1021 gcataacgct gaacaagcat cagggtatcc gcgcagccct ctgctggacg gcagaaatag
     1081 cccatttggc acgccagcac aatgatgcca atgtgcttgt catgccaggg cgattcatca
     1141 gtaccgaaga agccgacatg attatgaggg aattcttcag tacaccattc gaaggcggac
     1201 gccaccaacg aagagtggac aagataccgg tacacttgta aagcaataga atcaccttct
     1261 ttatgatatc cgcccgaagc tctgacattc tgatagaatc gtgagaaact tcgggctttt
     1321 tatttgcccc tttttcttat ttttcacagt gaagatgctc attgtcttca aataaaaact
     1381 atctttgtgg ttcgataacc cggatatttt ttagatatgg aacgactgaa taccataaaa
     1441 gagcttatca accagggaaa tgtagagcaa gccatccagc agcttgacga aatactgcaa
     1501 acagactttc ccggcaaaga cgaagcttac tacctgcggg gaaatgccta tcggaaacaa
     1561 ggcaactggc aacaagcact gaacaactat cagtatgcca tcgacctgaa ccccgaaagc
     1621 ccggcacaac atgcctatca aatggctatg gacatcctga acttctacaa caaggatatg
     1681 tacaatcaat aaataaagaa cgtaaattat ggcaaaaatc aaaggagcaa tcgtagtaga
     1741 caccgaacgt tgcaaaggct gcaacttgtg tgtggtagcg tgtccgctca acgtaatagc
     1801 cctcaccaag gaggtgaatg tgaaagggta taactatgcc caccagatat tggaagatac
     1861 ttgtaacggc tgcgcctcgt gcgccacagt atgtccggac ggatgtatct cagtatataa
     1921 aataaaagta gaataaatct gtaaatcagt agaatatggc agaagaagtt gtattaatga
     1981 aaggaaacga agccatcgcc cacgcagcca tccgttgcgg tgcagacggt tacttcggat
     2041 atcccattac tccgcaatcg gaggtattgg aaactcttgc cgaactgaaa ccctgggaga
     2101 cgaccggcat ggtggttctt caggcagaaa gtgaagtggc agctatcaat atggtgtacg
     2161 gcggtgccgg aagtggtaaa atggtcatga cctcctcctc cagccccggt gtcagcctaa
     2221 agcaggaagg tatctcttat ctggcaggtg ccgagctgcc ttgcttgatt gtaaacgtta
     2281 tgcgcggcgg tcccggtctg ggaaccatcc aaccgagcca ggccgactat ttccagacag
     2341 taaaaggagg cggccacggt gactatcgtc tgattgccct tgctccggct tccgtacaag
     2401 aaatggcaga tttcgtagga ctggcattcg aacttgcctt caaataccgt aatccggcaa
     2461 tcatccttgc cgacggtgtc atcggccaga tgatggaaaa agtggtgctc ccggtacaaa
     2521 agccacgccg caccgatgcg gaagtcatcg aacaatgccc atgggccact accggcagaa
     2581 ccaatggccg caaacccaac gtcatcacct cattggaact gaaaccggaa gaaatggaaa
     2641 agaacaacat ccgtttccag gccaaataca agcagataga agagaatgag gttcgcttcg
     2701 aggaaattca ttgcgatgat gccgactacc tgattgtagc cttcggctct atggcacgca
     2761 tcggacagaa agcaatggag ctggcacgcg aagaaggaat caaggtaggt atgctccgcc
     2821 ccatcacgtt gtggccgttc ccgaccaaag ccattgccgc gtatgccgac aaggtgaaag
     2881 gtatgctcgt tacagaattg aatgccggac agatggtgga agatgtccgc cttgccgtga
     2941 acggtaaagt gaaagtggaa catttcggac gcctcggcgg cattgttccc gatccggatg
     3001 agatagtaga tgcattgaaa gaaaaactga ttaagaaatg aatcctgata aaataagaaa
     3061 cgtactgaac attctcttca tggtacttgc cttggcagct atcattatat attttgctgc
     3121 aaaagatgac ttcaagctgt tcatctacgt ctgcggcgcg gcgatattcg tcaagttgat
     3181 ggagtttttc atacggttca ccaacagata ggagaagtga ttatgacaaa agaagatatt
     3241 ataaagcccg agaatctggt tgccaagaaa ccgactctga tgaacgacaa tcccatgcac
     3301 tactgcccgg gatgcagtca cggcgtagtt cataaactcg tagccgaagt tatcgaagaa
     3361 atgggactgg aagacaaagc aataggcatc tcccctgtgg gatgtgccgt gttcatctat
     3421 aattatatag acatcgactg gcaggaagcc gcccatggac gtgcgcccgc acttgccact
     3481 gccatcaagc gcctttggcc agaccgcctg gtgttcactt accaaggaga cggcgacctg
     3541 gcttgtatcg gtactgccga aaccatccac gccttgaacc gcggcgaaaa catcaccatc
     3601 atcttcatca acaatgccat ctatggtatg accgggggac aaatggctcc cactaccctt
     3661 gtaggcatga agacatcgac cagcccttac ggacgtgacg tgcatctgca cggctatccg
     3721 ctgaagatgg ccgatattgc tgcacaattg gaaggaaccg cttacgtgac acgccaaagc
     3781 gtacagtccg ttcccgccat ccgcaaagcg aaaaaggcta tccgcaaagc attcgagaac
     3841 tctatggcag gcaaaggttc caaccttgtg gaaatcgttt ccacctgtaa ctccggctgg
     3901 aagatgtctc ctgcgaaatc caatgaatgg atggtagaga acatgttccc cttctatccg
     3961 ctgggcgacc tgaaagataa ataatcatgc taaagacaga agaacaatga aagaagaaat
     4021 cattatagca ggcttcggtg gacaaggtgt attgtccatg ggaaagattt tggcatattc
     4081 cggattgatg gaaggcaaag aggtgacttg gatgccggct tacggaccgg aacaacgtgg
     4141 tggtacagcc aacgtaacag tcatcgtaag tgacgagaaa atatcctcac ccatcttaag
     4201 caagtacgat gccgccatca tcctgaacca gccgtcactg gagaaattcg aaagcaaggt
     4261 aaaacccgga ggcgtactta tctacgacgg ttacggcatc atcaacccgc cgacgcgtaa
     4321 ggacatccac gtttaccgca tcaacgccat ggatgccgcc aatgaaatga acaacgccaa
     4381 ggcattcaac atgattgtat tgggtggatt attgaaaatc aagccgatgg ttacactgga
     4441 cagtgtactc agaggattga agaagacact gcccgaacgc caccaccact tgataccgat
     4501 gaacgaagaa gctatcaaga aaggaatgga acttattcag gaaatgaaat gaaaggctat
     4561 gtaaagccac tccccataag aggaggaact ttacgccaga ataagagata aaggaaaacg
     4621 gataagccct tgtgatattg atttattgca agggcttatt tcatttcaag ccggaaaaag
     4681 tatggattca agggcagaga accggaagca gtatagaaca aaacagaaaa caagacagtt
     4741 taaaagaagc aaaaaaggct gaattcagta agcaaataat tttttattgt atctttgcgc
     4801 ctaattatga gacgaattgt actgacatat atatttctgt ccgttatagg gatatggggg
     4861 gctatggcgc aaaacacctt aaacccgatg aacaatcgcg accggttcgg taaccagatt
     4921 gacccgaata cccagccgga caatctggaa gacagtacca atactgagat tcaaagtctt
     4981 ccacccaagc tttacatgtg gaaactaagt gagacactgg gcaaccgtac catcatacct
     5041 gccgacacag ccagcctcaa cttccagagc accaatctgg tggaaggaat gttcggccac
     5101 tacaactact tgggaaattt aggttctcca cgtctctcac gtctgttctt cgaacgggag
     5161 gaaagcgaac ctaccatctt catggctccc ttctccagtt ttttcacacg tcccgaccag
     5221 gtgcttttca ccaacagcaa cgtgccttac accaatctta cctactacaa ggccggcaac
     5281 aaagtgaacg gtgaagaacg cttcaagtcc tatttctccg tcaacgtcaa caagcagttg
     5341 gcatttggct tcaacatcga ctatctgtac gggcgcggtt attaccagaa ccagtccacc
     5401 tcgcacttca atgcaggact gttcggtagc tatatcggcg agaaatacca ggtacaagca
     5461 gtctacaaca actttttcct gaagatgaac gagaacggcg gtattgcaga cgaccaatac
     5521 atcacccgtc ccgaaaacat gtccggagga aagaaagagt acgagtccac cactattccg
     5581 gtcaaattgg aacagagttc caaccgtaac aaggattttt atatctatct gacacagcgc
     5641 tatcgtcttg gttttacgcg gagagtacgg aacacacaag aaggcaaacc gacggtatcc
     5701 gcacccaaag cctcatcctc cccgtcctct gaatccgaaa tatccgcttc gaacaacgac
     5761 atagcattgc caaacgacag catagcatca aaatcggtca gcacacttgc agctgccaat
     5821 gacagcctgc cgtctgtttc taccgcagac aacgactcac ttttcgaaga agagttcgtc
     5881 cccgtcacca gctttatcca taccttgaaa gtagagcggt cgcggcacca attccgttcg
     5941 ggaagcgagc ccgaaggatt cttcccggaa gactacaagc tttacaagaa ttacagcaac
     6001 gactccacca cggcattcag tgtaaagaac gtgttcggaa tagccttgct ggaaggtttc
     6061 aacaaatatg ccaaagccgg acttacggct tatatctccc acaagttcag ccggtacgac
     6121 ctgatgaaca cggacacgct taccgacatg cgccgcatcc gctacaccga acaggaaatc
     6181 ttcgtgggcg gcgagctcgc caagcgcgaa ggcaaactgt tgcactacaa cgtaaacggt
     6241 gaagtggggt tggtagacaa agccatcggg cagttccgcg tcaacgccaa tctggacctg
     6301 aacttccgtc tatggaaaga tacggtgaac ttctacgccc gcggttatgt gagcaacacg
     6361 cttccttcct tctatatgcg tcattatcac tccaaccact acaactggga caatgacaac
     6421 atggacaaag aattccgtac gcgtgtggaa ggcgagctga acatttccca ttggggaacc
     6481 aatctccgtg ccggtgtaga gaatataaag aactacactt acttcaacca aagcgccctg
     6541 cccgaacaga acggaggcaa catacaagtg ctgtctgcca cgctgaaaca agacttccgc
     6601 ctcggtgtct tccacctgga caacgaggtg acctggcaga agacgagcaa tgaaacagta
     6661 cttccactgc cccaactctc gctctaccat aacttctaca tattggctaa actcgccaag
     6721 aaggtgctga ccgttcagtt gggtgccgat gtccgttact tcaccaagta caacgcaccc
     6781 gcctatgcac ccggcgtcca gcaattccat ctgcaaccta cggacgattt ggtggaaata
     6841 ggcggttacc ccatcgtaaa cgtatatgct aacctgcact tgaagcggac gcgtatcttt
     6901 gccatgatgt atcacgtcaa cgcgggtatg ggaagcgcca attccttcct ggtgccgcac
     6961 taccccatca atccgcgctt gttcaaaatt ggcgtctcat ggaatttcta tgactaacag
     7021 atgactgtat gacgaaaagc agactgctca aatacgcact tctgggaatt gcagcggctc
     7081 tcattgccca ctatctcatc aagaaagaag agaaaccgaa aggtcatccg cgcgattatg
     7141 ccgagataac tgccgaaggc atcatacatg cttcgacgga atacaactcc atcagtttct
     7201 atgtggatga tgacaccttg tccggtttcc actacaagct gatagaagct tttgcacgcg
     7261 accacgggct gcaagcggcc atatcaccgg aaatgagctt caacaagcgg ctggaaggcc
     7321 tggccgacgg gcaatatgac gtgattgcct acggcatcct cgccaccagt gagctgaaag
     7381 actccttgct gcttaccacc cctattgtgc tgaacaagca agtgctggtg caacgcaagc
     7441 ttgagaatat ttccgactcg tcattattca tcaaaagcca actggacctg gctggaaaga
     7501 cactgcacgt agtgaaaggc tccccttcca tactacgcat ccgcaacctg ggaaatgaga
     7561 taggcgacac catctacgtt gaggaaatag agaagtacgg ttccgaacaa ctgattgcct
     7621 tggtagccca tggagacatc gactatgccg tatgcgacga aagcattgcc cgtaccgcag
     7681 ccgacagcat tcctcaaata gacatcaata ccgccatcag cttcacgcaa ttctattcct
     7741 ggggggtaag caaacagtcc cctatcctgc tggacagcct caacacatgg ctggatagtt
     7801 tcaaaaaggg aaaagaatac aagaaaatct acaaacgata ctacgggaaa cgaaactaag
     7861 ctgcactttt ccatacacgc agcatatccc tacttttaca actagttatc aatcagcagc
     7921 ttattactgc aaaatcctgc atacattttg cagtgccact gcaaagccgt tgcagtgata
     7981 ctgcaacacg tttgcagtcg cactgcaaaa tacatgcagc aagaatgcaa acaagatgca
     8041 gtcatcaaat acccatatcg atattacggc atacccgaag taaagaatta gagtccttcc
     8101 acctccctta gccacatctc cgacgaagca tcgctcggca ttctccaatc accgcgcgga
     8161 ctcagagaga tactgcccac cttcggacca tccggcaaac aggaacgctt gaactgctgg
     8221 ttgaagaaac gacggcagaa agtctgcaac cattttttga tggtttcttc atcatacatc
     8281 cccttgaatg tccgtgctgc caggaaaaat atcttggaag gacggaaacc gcagcgcagg
     8341 aagtaataaa ggaagaagtc gtgaagctca tacggcccca ccaaatcctc ggtaatctgc
     8401 tggatattac cgttctcatc tgccggaatc agttccgggc tgatgggagt atccacaata
     8461 tcgagcaagg tagcacgtga agcatcgtcc atatcatgct ctgccaccca tttcaccaag
     8521 tgcttcacca gagtcttggg gacgctggca ttcacaccgt acatcgacat gtgatcgccg
     8581 ttgtaagtgg cccatcctaa agcaagttcc gaaaggtcgc ccgtaccgat aaccattccc
     8641 caggtctggt tggcaatatc catcaagatt tgggtacgct cccgtgcctg cgcattctcg
     8701 taaaccacgt cgtgcacatg gacatcatgg tctatgtctt tgaaatgctg tatgcaggcc
     8761 tccttgatac tgacttcgcg gacagtcaca ccgagggagt tcatcaggtc gatggcattc
     8821 gtgtaagtac ggtcggtcgt tccgaatccc ggcatggtga caccgacaat accctggcgg
     8881 gaccatccca acttatcgaa agtctttacg caaaccagca gcgccagcgt agaatccagt
     8941 ccacccgaaa tgccgataac ggcactcttc gctttagtat gcaccagacg ttgcgccagt
     9001 ccggacacct ggatggagaa tacctcctca cagcgttcgt ccaacgctat cccctgcgga
     9061 acaaatggat gcggttcaaa agtacgtgtc aggttcaaat ccctgctgtt gacatactcc
     9121 gtagagattc gtaccggaag ggccgaaaca caatttgcat ggcaagccgc gaaggtcgta
     9181 ttcacccggc gctccgtacg caagtgttcc acatcaattt cactgatgac cacctgccct
     9241 tcgaaagaga agcgttcgtt tgccgccagc agagtcccgt tctcataaat cagtccgttg
     9301 ccggcaaaca ccacatccgt agtggattct ccgaaaccgc atgagctgaa tacataaccg
     9361 gcaatgcacc gtgccgactg ctggctgata agcgagcgca gataattgtg cttgccgata
     9421 ccttcattgt cggccgaaag attgaacaag atttccgcac cttgcagtgc cagcgtggaa
     9481 ctgggcggta tgggtgccca caaatcttcg catatctcca ctccgaaagt ggtatctgcc
     9541 gtttcgaaca gcaggtctct ccccatcgga ataatctgcc cgcaaaggcg cacactgttt
     9601 tctgccacat cacatgcgga agtaaaccag cgcttctcat aaaactcctt ataattggga
     9661 agataagtct tcgggacaac gcccagcact ctccccttct gaatgacaac cgccgcattc
     9721 agcaacacac cgttcagtgc aacgggcatg cccaatatcg aaatgatatc catctggcgc
     9781 gtattgttca gaatctgtat cagccccatt tccgcctctt cgagcagaag ttgctgggca
     9841 aagaggtcgc cacaagtata tccggtaatg cacaactccg gaaaagcaat gatttgcaca
     9901 cctttcccat cggctataat aatctctttt tcaatctctg aggcattgaa cttacagtca
     9961 gccaccttga cacggggcac agccgccgct acttttacat atccgtaatt cataaggatg
    10021 ctatattatt tattcggtgc aaagatacgg caaaattctg attaagagag ataagggaaa
    10081 aacgttttat ctatatcggc acgagaaact gactaaaacc gggtgcatcc tgccttcgct
    10141 tttatgacaa aaatacggca acctacctac aagaagagga acatatataa acaattttaa
    10201 tgaccgcaac taaaaatttt ccaaaaatct tttggagaat tataggaact tcctatcttt
    10261 gcaagtgaat taaaaatgta ataattacaa gtttgaaact ttagattata tggatgtagt
    10321 aaaacgattg cagaatcata atatcaagcc ttcagtacag cgcatagcca tcatgaatta
    10381 cttgatagag catcgtacgc atcccacggt ggatgaaatc tatacggcac tgtctccctc
    10441 cataccgaca ctgtctaaaa caacggtata caataccttg aaactactga gcgagcaagg
    10501 tgccgcacaa accctgacta tcgacgagcg taacacatgt tatgatgccg ataccagccc
    10561 gcacggtcat ttcttgtgca agcgttgcgg aaagatttat gacttgatgt gcaataacaa
    10621 catcaagaaa gtggtcgaca tggatatgga cgggcacgat gtgcaggaaa tccactacta
    10681 ttataaagga atctgtaaac attgcataga agaagaacgt ttaagaacaa caaagaataa
    10741 ctaattcaac taattaaaat ctgagagaaa atgaaaaaat ttagatgtac tgtatgcggt
    10801 tacgtatacg aaggagatgc agctcccgaa aagtgcccat tgtgtaaagc tcccgcaagc
    10861 aagttcgtag aagttgaaga agcaacagct gacggcccgc tggtatttgc cgacgaacac
    10921 gtaatcggcg tagccaaagg ttgcgacgac gaaatgatta aggacctaaa caaccacttc
    10981 atgggcgaat gtacagaagt tggtatgtac ttggcaatga gccgccaggc agaccgtgaa
    11041 ggttatcccg aagttgcaga agctttcaag cgttacgctt gggaagaagc agaacacgct
    11101 tccaagtttg ccgaactgct gggcgactgc gtatgggaca ccaagacaaa cctcgaaaag
    11161 agaatgaacg cagaatcagg tgcatgcgaa gacaagaagc gtatcgctac ccgtgccaaa
    11221 gcattgaacc tcgacgctat ccatgacacc gttcacgaaa tggctaagga cgaagcccgt
    11281 cacggtaaag gtttcgaagg tctgtacaac cgctatttca agaaataatc ctatactttt
    11341 atagtaatgt gaagaaaagg gactgctaat gttagtaagt cccttttttt attccaactt
    11401 ttttcacttt acaatgtcac gtttgtattt cccattcgtc ttatctgtgt aaatggaact
    11461 caaagaattc aaaataaccg ttcttccact ccgtgccaag ctgttgaact atgcacggaa
    11521 gttgaccgac gaaccggagg atgcagaaga tgccgtccag gaggtactgc tcaagctatg
    11581 gaacaaaagg cttgaactgg agcaataccg gagcatcgaa gcatttgcca tgacgttgac
    11641 gcacaacatc tgtatagata tgtggcgctg caaacgcaac gacaacctat ctcttgacat
    11701 tgtgcaggcg gcatccccca ccggaacacc ggaacggctg ttggaaatca aagatgaaat
    11761 ccgcttgatg cacgaaatca tccactcgct gcccaatctt caacgcacca tcatgcagat
    11821 gaaagacatc gaaggatacg aaacggacga aatcgccgaa atcacgggat gcggaccgga
    11881 agccatccgc agcaatctgt caagagcccg gaagaaagtg agagacgttt acctgcgaac
    11941 catacaagaa agaaaagaaa ggagaaatga gccatgaaga tagatgaact gctggataaa
    12001 tatttcgaag gggaaacttc ctgcgaagaa gagcgtgaac tgcgccgttt ctttaccgaa
    12061 gaggaagtgc cggagcacct gcaaacgtac cgccccctat tcgcttatct gaaccgggaa
    12121 gcaacttcaa tggcagaacc gacagaggaa aaatccgtaa caacagaatc ggcaaaggaa
    12181 gtacccgcac agcggaagcc tttccgtctc tatcgcacat tctatgctgt cagcggcatt
    12241 gccgccggat tgctcctgct tctcggggta gctaagatta tatttccgct ttccggtgtt
    12301 cccgaaaatt atgtcgtcat cgacggccag cggtatacag acgagaaact ggtggaagcc
    12361 aaagcactag aagccctgca gaacgccagc ttcacggatg aagatttaag caacttactg
    12421 tttcaacact aatataacaa ggttatgaaa acatctatac tgatttgcat acgtagtctg
    12481 tgcctctttt ccctgctgat ttgcctgcca gcctttgtac atgcacaaga gagactgcaa
    12541 atagccgacc tattcagcaa gtatggcgag caaaaggacg tgaccagggt agaactgaac
    12601 ggcagtatcc tgaaatctta ccgcatgact acctacaaga gccttgtgtt caagaatgta
    12661 tccccctatc gccgggaaat tcagcaggcc attgtacacg acaagcaaga taacgcaaag
    12721 aaggcgcagg aggtaatgga aagcggtgtg ctgcgtagcg cttattacca actgaaagag
    12781 gtggaacgca atggaaagaa gctgaaccgc tacatcattt tcaagatagg aaaagactcc
    12841 atgggcactt tgatttacat agagggtctg ctcagtgaaa aggaaatgat ggatatgctt
    12901 tacaaatcgg aataacacta aaaacaatat acgatatgaa aaccagaatt atgattttgg
    12961 cctgcctgct tgctgtgcca gccggccgca tggcagcaca acaacagact gaccctgaac
    13021 agaaagctac agtacagaca caaggcgact ccatcatcat ccggaaagga aaaggagaca
    13081 tgcgcatcaa ggtgtacgaa gagcagttgg aagacggaga aaagaaagaa gtacaaattt
    13141 atgaaggagt ctatctcgag aaagtggatg cagacaagcg cactttcctc gacgcactgc
    13201 cattcatccc caaaaagaga agatacaatg cttacgaacc gcactgttcc ggtctgtata
    13261 ttggctacag ccggctggct aacgacttcc tttccttcgg agcaagcgac aagatgggac
    13321 tcgacttatc caagtcatgg gaattcggct tcaacatcct ctccgtatat cacaacttca
    13381 agaagaaccc gcattgggga atcaacctgg gagtcagctg gggataccgt tctttcaata
    13441 tcgacggtaa ctatgccttg ctgaaggaaa acggaaccag catcttcacc gcaggcaacg
    13501 aagacaccag ttacaataaa agccgtctgc gccatttctt cttccgtgta cccgtattga
    13561 tggaatggca gcaaagagtg ggaagaaaca aagtgttctt caatgccggt cccgaatttg
    13621 agatacgtca cagcgtgaag tcattctcac acatcaacgg aggcaagaag aaaaccgtag
    13681 gcaaaggtat gtatgtgcag cccgtcggca taaacctgct ggcacaagcc ggttatggta
    13741 atatcggcat ttacctgcgc tactccacat acggattatt ccagaaagac aagggaccgg
    13801 aagtatctcc ctattcattt ggcgtggcat ggtatctgta atccctcccc tataacacaa
    13861 gactccccga aatgtatttg tacattccgg ggagttcttt tataccctaa ggtattgaca
    13921 atgaaaggtt atctgcaata aaaattgttc ttctaaaaac gcatgcccaa tgtaaatagc
    13981 actttactgc gagtgttggt aacttccgtt gttggcggtg ttaccaagcc atttatatca
    14041 ttataaaacg gatagaaatc agatttataa gtatcgaatt tataagccaa atccgcataa
    14101 aacgaagaaa agcgataacc gatacctaaa gtgaaagtat tcatcgattt gctattggca
    14161 aaatccgtat ctgtatttat agaattggaa ggcaatgcct taatagcatc ctttttatag
    14221 gctgcagtac tgtaattgta accggcacgc agagagaaag caggtatcgg cttgtattct
    14281 gctcctaaac gaagcgtact tacccccttc atacagaggt cagcctcacc cgtttcccat
    14341 gccatctcat caccttcagg atatttgaac ttcatgcttg agtagtcctc atattcatat
    14401 tcagctccca aagccagatt attaccgact gtatagccca aacttgcatt aaatacccac
    14461 ggggtttgca gcttaaaatc acggtccata tctctaccgc ctaatgcaga ataagtatcc
    14521 acagtggtac gagtaggagt ttcatcccca gc
//
