LOCUS       c00131_gnlPro..         7903 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ICGLFAJH_131.
ACCESSION   c00131_gnlPro..
VERSION     c00131_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 10:23:41
            Original ID  :: gnl|Prokka|ICGLFAJH_131
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7903
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7903
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2228:7902]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2229..7902
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..7903
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..7903
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..139)
                     /locus_tag="ctg131_1"
                     /transl_table=11
                     /translation="MVYDLTMLKTFYAAYSEKIERVRNVLRRPMTLAEKILYAHLYDGD
                     K"
     CDS             254..2167
                     /locus_tag="ctg131_2"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQVLLRMEYEYEKEEFKRQTENMG
                     VARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGTSKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NAELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCYEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     IGGNRILEEKIDIGIISPYKAQVQYLRSKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             complement(2229..3272)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg131_3"
                     /sec_met_domain="IlvN (E-value: 2.7e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.4e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIIMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(3323..4075)
                     /locus_tag="ctg131_4"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(4072..4632)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg131_5"
                     /sec_met_domain="ALS_ss_C (E-value: 4.2e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(4665..6416)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg131_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.9e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAKRPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(6508..7902)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg131_7"
                     /sec_met_domain="ILVD_EDD (E-value: 2.1e-166, bitscore:
                     543.3, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNIPTVFVSGGPMEAGEWNGQHLDLIDAMIKSADESVGDKEVAQI
                     EQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATHENRKKLFEDAARLIVENA
                     FRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLHLLAVAHEAGADFKMDDID
                     MLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGGLVDTNVRRVDGMTLAEAI
                     DRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELDTDRATGCIRDLEHAYSKD
                     GGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDAACDGILGGKVVSGDVVVI
                     THEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHVSPEAAAGGN
                     IGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNREVSKALKAYASMVSSADKG
                     AVRLID"
ORIGIN
        1 ctttatcccc atcatacaaa tgagcataca aaattttctc tgctaaagtc atcggacgcc
       61 gcagtacgtt ccgtacgcgt tctatcttct ccgaataagc agcataaaac gttttgagca
      121 tcgttaaatc atataccata accactattt tttagttttt cattattgta aagattacaa
      181 attaatatca taaacaaata aaaaggctga atagtttaac aaaataaagc attttttctg
      241 tcggaagcga agaatgatta cctttgcaac catgaaggaa caagattcaa atagtcctat
      301 tattcacctc cagcagcaac aagttttgct gcgcatggaa tacgaatacg aaaaagagga
      361 attcaaacgc caaaccgaaa acatgggagt tgcccggaaa gtgaaacggg gactttgctg
      421 gtatcctgcc actccgggac gaagttacta taattcactg aatcaattag taatagaaat
      481 tacacacaca gaaaataccg atatagaaca taattttgag ttcggccgtc ccgtatgttt
      541 tttccgccag tctgctgatg gaaaaataac ctatatgaac ttcaccgcta ccgtaagcta
      601 tgccgacgag acacggatgg tagcgataat gcccggagcc ggtgccgtta tggaagtgca
      661 ggaaacggac aacctcggcg tgcaacttta tttcgacgaa acatcctatc ggaccatgtt
      721 cgaagccttg gaagatacgt tacgctccaa aggcaaccgc ctggccgaat tgcgggacat
      781 attgctggga acctcgaaag ccggtttccg agagctctat cccgtacggt ttccctggct
      841 gaactccacg caggagacag ctgtaaacaa agtgctgtgt gcccgcgacg tggccattgt
      901 acacggtcct ccgggaaccg gaaaaacgac caccttagtg gaagccatct acgaaaccct
      961 gcatcgggaa ccgcaggtac tggtatgtgc ccaaagcaat actgccgtcg actggatttc
     1021 ggaaaaactt gtggaccgtg gcgtcaatgt cctgcgtatc ggcaatccga cccgtgtcaa
     1081 cgacaagatg ctttccttta cctacgagcg tcgtttcgag aaccatccgc tttatccgga
     1141 gctgtggagc atccggaaaa atctccgtga actgggcagc cgtgcccgcc gtggcagcta
     1201 tgacgaacgc gaaggagtac gcagccgtat gagccgcctg cgcgaccgcg ccaccgcatt
     1261 ggaaatacaa atcaatgcag agctttttga tggggcacat gtcatagcct ccacgctagt
     1321 aagcagcaat caccggctgc tgaacggacg ccgtttcggc acccttttca ttgatgaagc
     1381 agcccaggcc ttagaagctg cctgctggat agctatccga aaagcagacc gcgtggtgtt
     1441 ggcgggtgac cactgccaac ttccgcccac tataaaatgc tacgaagctg cccgtggagg
     1501 tctggaacga acattgatgg agaaagtggt gtccaacaaa cctgccgttg tctctttgct
     1561 gaaagtacaa taccgcatgc acgaggaaat catgaaattt ccttcccaat ggttttataa
     1621 tggcgagttg gaagccgctc ccgaagtgcg ttaccggggc atcctggact gggatacccc
     1681 catccactgg attgacacct ccgaaatgga tttcaaagaa gaatttgtgg gagagacttt
     1741 cggacgcatt aataaggcgg aagcggacct gctcctatca gaactgaaaa tctacatcaa
     1801 ccgtatcggt ggcaaccgca ttctggaaga aaaaatagac atcggcatca tctcccctta
     1861 caaggcacaa gtgcaatatc tccgcagcaa gataaaggca gacgcttcac tcaagcctta
     1921 tcgcagcttg ttcactgtaa atacggtgga tggcttccaa gggcaagagc gcgatgttat
     1981 cttcatcagc cttgtccgtg ccaacgaaga aggacagata ggattcctga atgatttaag
     2041 gagaatgaat gtagccatca cccgggcacg tatgaagctg gtgatattgg gagaggcaga
     2101 gacgctgaaa catcacggtt tttaccggaa gctattggag tttattcaaa atatagggaa
     2161 tcaataataa agaaataccc cctccggtaa caccgaagag ggtatttcac ctatttatat
     2221 aaagctgatt aattgttttc cggacgaagt ttacgaactg taacagctgt ctgccacatt
     2281 tcgctttcac gcaaggcttt caattctgca ttcagcttct cacgataatc gggtttggag
     2341 ttactgtcga tagaaatctg agcttcgttg cccgacttca cacttgcata caatttctgt
     2401 acaaccggct tgatggcatc atggaacggg gtcatccaat ccagcgcacc acgctgtgcc
     2461 gtagtagaac agttggcata catccagtcc ataccgttct tggcaaacaa tggcatcaaa
     2521 gattgagtca actcttccac tgtttcattg aatgcttcag aaggagtatg gccgttttcg
     2581 cgcaatactt catactgagc caacagcaat ccctggatag cacccatcaa tgaaccgcgt
     2641 tcaccggtca agtcggaagt ggcttcgcgg atgaaagttg tctcgaacaa atatcccgaa
     2701 ccgatgccga tacccagtgc aatcgtcttg tcaaaagcct tacccgtagc atcctgatag
     2761 acggcatatg atgagttcaa gccacgaccc tcgaggaaca tggtacgaag tgaagtaccg
     2821 gaacctttgg gagcaaccat aataacatca atatctttag gaggaaccac gccggtacgg
     2881 tcgttccagg taatagcaaa accatgagag aagtaaagag cctttccggg agtcaaataa
     2941 ggtttgatag tcggccatac agacattaca gctgcgtcag acaacagaca catgatgata
     3001 gtacctttct gacaagcctc ttcgatgccg aacaaagtct cacccggtac ccatccgtca
     3061 gccacagcct tttcgtatgt cttacccgga cgttgtccta caatcacatt gaaaccgtta
     3121 tcacgcaagt tgcaagcctg gcccgggcct tgtacgccat aaccgattac tgcaattgtt
     3181 tcatctttca aaatctcacg tgctttttcc aaaggaaatt cttcgcgggt cattacattc
     3241 tcaataacac cgccaaaatt caattgtgcc attttttgtt ttaattttta tttgtggctt
     3301 acgccaacgt tgataaattt atttatttct ctgtaaatat cactttagag cgacagacca
     3361 cttcgctgcc attctttttc acctccacat cgtaaacgcc ctcaccggca tcatccatga
     3421 acaaagtcaa ctcatcccca taatagcttt cggctacata tgccatttca aaacgacgga
     3481 tgcgcttctc cttatacatc tctatcggga acaaatcaag gatatgctcg atgtaacgga
     3541 tgctgttcac atgcccgtta atgtcaatat cactgtattt ggctaccaaa gcagcaaccg
     3601 gttcctttga ggccaccttt atccgcgaag gtttttctat cgggcaaggc tcatcgcaaa
     3661 cataatctac aatgctgcca ctatgaagag ccagcaaatc tgccggctta cgggtattca
     3721 tgctaatcat cgcccaaacg gaacgtgcat acccaatctt cttaccctcc ttatcgatga
     3781 tagcgaaatt acggtctgta aaaaggcgat agacattctc cacccaagtc tgaatggaga
     3841 aatcttcgta ctgataaggc atttcatcca gttcgacagc cagacgggac aatacccaag
     3901 tataattgtc ctcgtttaga gtcgcgatgc caaaaccgcg gtcgctggca tggaaacccg
     3961 cacaattcaa caaatggttg cccaatactc ccattgtcag ccgtccggta aagtcgacat
     4021 gaaacggttc ggcaacaaac ttgtaggtac ctattttatt gttctcgctc atcatgattc
     4081 ctggtgttta ctttgacgat attttgcttc acggtccgcc agatattcat tgacacgctc
     4141 aaagcagctg gtcgtaatgg ctacgcgacc cgaacggacg aactgaagta cgcaatccaa
     4201 ctggcgcaac tcctcataaa gattggttat ttcctcactc atgccattct tctcaacaat
     4261 ggcaaataca gcattcacct ccacaatacg ggcattgtac ttacggatta ctttggacac
     4321 ctccggtttt tcttccagcg taggggtcgt tattttataa agggcaatct cgtgctgata
     4381 gatttcatca tccgtgaaat aatgggcttg cagcacatct attttcttgg taatctgctt
     4441 ggtcaccttt tcaatggtat ccttatccgt ccaagcggta atggtatatt tatgtacccc
     4501 cttgatggag gaggccgata cattcaaact ctcgatgttt atctgccggc gggtaaacac
     4561 agccgtcacc tgattcagca aaccggcaaa gttttccgaa tgaacaatga ttgtatatag
     4621 ttttttatcc atagatagag taaattcttt aatttcgcat gacttcagca ttccaacaac
     4681 atctgattga ccgaaccgcc cggaggtgtc atcggcatta catttccttc ttcctccaca
     4741 caagcttcga gcaggaacgg tccgtcagtc gctatcatct cgtcaatcgc ttttgccagc
     4801 tcctcgcggg tcattaccct gcgtgcagga atatcatatg ccgaagcaat cttcatataa
     4861 tccggattca tcatcggagt aaacgaataa cgacgattga agaacatcgc ctgccattga
     4921 cgaacattgc ccaagaagtt attgttcaac agaatcatct tcaccggagc cttttgttcc
     4981 atgatggtac ccagttcctg caggttcatc tgcaagccgc cgtctcccat gaatacgcat
     5041 accgtgcggt ccggacgtcc aaaagtggca ccgatagctg ccggaaggcc gaagcccata
     5101 gtacccaggc caccggaagt aacaatgcta cgttccttgc tgtatttgaa ataacgggcg
     5161 gacatcatct gattctggcc gacatcagtc accaatatcg cctcgttatg ggtagcctca
     5221 ctcacagcac gcaccacctc acccatgctt agcgcttttc ctgccggatg taattccgga
     5281 cggattacct tttcctcttc cacttcctcg tattgccgga aactgtcaat ccattcctga
     5341 tggttggcgg gttccagcaa ttgggtaacg gcagccagtg tctctttgca atctcccagg
     5401 acagcaacat cagtctttac attcttatct atttcggcag ggtcaatatc aaagtggata
     5461 atcttcgcct gcttggcata tgtttccaat ttacccgtca cacggtcatc aaagcgcatg
     5521 cctacggcga taaggacatc acatttattg gtattgatat tgggccccag gttaccgtgc
     5581 ataccaagca ttcctttgtt caacggatgg ttcgtaggta atgcggaaag tcccaataaa
     5641 gtgcatccgg caggcattcc ggctttctca atgaaagcac gaagctcttg ctgggcttct
     5701 cccagctcca cgccttgtcc aaccagcacc aaaggccgtt tcgcaccatt tattaattca
     5761 gcagccttcc gtatggcctc cggctccatt tcgggaacgg gaagatagct acggacatag
     5821 tccaccttag taggcgcata ttctgttttc tccacttggg cgtttttagc aaaatccagc
     5881 acgaccggtc ccggacgtcc gctctttgcc acatagaaag cacgtgccac tgcccaggcc
     5941 acatcttctg cacgacgaat ctggtaactc catttcgtga taggctgagt aatgcctacc
     6001 aagtccactt cctgaaatgc atccgtaccc aagaagttcg tccctacctg gccggcaatg
     6061 acaacgatag gcgtactgtc aatcatggca tctgcaatgc ccgtgatagt attggtagca
     6121 cccggtccac tggtaaccag acaaacgcca acctcgcctg atacacgtgc aaagccttgt
     6181 gccgcatggg ttgctccttg ttcatgacga accaagatgt ggttcaattc cttccgatgg
     6241 tcgtataagg catcgaatac cggcatgatg ctccctcccg gataaccgaa aatagtcttt
     6301 actccctgat gctccagaga gcgcatcaat gcttctgcgc ctgttattag agcctcaccc
     6361 cgaccctctc cttgggagag ggaggaaaag ttactctttt tattattatc agccatactt
     6421 tatctattca ttatatttaa aagctcaata gtagcttgaa aaatttgttt cattctctcc
     6481 tcccctcgct ttcggaaagg ggggctttta atcaatcagc ctcacagccc ctttgtcagc
     6541 ggaactcacc atactggcat atgctttcaa tgctttggag acttcacggt tgcgggttac
     6601 cggagtcata gggcgtgctg caagctcttc atccgtcaac ttcacattga tagaacggtt
     6661 cggtatatca atttcgataa tgtccccatc cttaatcttg ccgatattac caccggcagc
     6721 cgcttcggga gaaacatgtc cgatacttag tccggaagta ccgccactaa aacgcccgtc
     6781 ggtaatcaat gcacactcct tacccagatg gcgggatttg atataagaag taggataaag
     6841 catctcttgc atacccggtc cacctttcgg cccttcgtga gtgatgacga cgacgtctcc
     6901 actgaccacc tttccaccca gaataccgtc acaagccgca tcttgtgagt cgaagacttt
     6961 cgctggcccc gtaaatttcc agatactctc gtctacaccg gcagtcttga caacgcaacc
     7021 gtcctgagct atatttccct tcaaaaccgc cagaccgcca tccttgctgt atgcatgttc
     7081 caaatcacgg atacaaccag tcgcacggtc cgtatcgagt tccttataag acgcattttg
     7141 tgagccgagt accagattga actttccggc tgccgcactg gagtatttct tgattgcctc
     7201 tttacataca ttagagctgg taatactata ccggtcgatt gcctctgcca acgtcattcc
     7261 atccacacgg cggacattcg tatcgaccaa tccgcccttg gcaagctcat ccatgatggc
     7321 aatgatgcca ccggcacggt taacgtcttg tacatgatac ttttgggtat tgggagctac
     7381 cttgcataag cagggggtct tgcgagagag catgtcaatg tcgtccatct taaaatccgc
     7441 tccggcttcg tgagccacag ccaacaaatg aagtactgta ttagtggaac cgcccatcgc
     7501 aatatccagc gtcatggcat tcaaaaatgc ctcgcgggta gcaatactgc gcgggagtac
     7561 actctcatcc ccttcttcat aatatctaaa ggcattctct acaatcaacc tggctgcatc
     7621 ctcaaatagt ttcttgcgat tttcgtgagt ggctacaatc gtgccgttac cgggcagtgc
     7681 caatccaatc gcttcattca ggcaattcat ggaattagcg gtaaacatgc ctgagcagca
     7741 tccgcaagtg gggcaggcat gttgctcaat ctgtgccacc tctttatcgc ccacactttc
     7801 atcagcagat ttaatcatgg catcaatcaa atccaaatgc tgtccgttcc attccccggc
     7861 ttccatcgga ccgcctgaaa caaacacagt cggtatattc agc
//
