LOCUS       c00369_gnlPro..         3415 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HABBHGLJ_369.
ACCESSION   c00369_gnlPro..
VERSION     c00369_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 11:13:55
            Original ID  :: gnl|Prokka|HABBHGLJ_369
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3415
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..240
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_1"
                     /sec_met_domain="ILVD_EDD (E-value: 4.4e-35, bitscore:
                     109.5, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKE
                     CALITDGRFSGGTSGLSIGHVSPEAAAXXXXXXD"
     protocluster    1..3415
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2860]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..2860
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3415
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3415
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             194..424
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_2"
                     /sec_met_domain="ILVD_EDD (E-value: 1e-16, bitscore: 49.0,
                     seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLPKRLPXXXXXXIKDGDIIEIDIPNRSINVKLTDEELAARLMT
                     PVTRNREVSKALKAYASMVSSADKGAVRLID"
     CDS             516..2267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAVQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             2300..2860
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_4"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-20, bitscore: 60.8,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             2857..3414
                     /locus_tag="ctg369_5"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHIL"
ORIGIN
        1 gacggtattc tgggtggaaa ggtggtcagt ggagacgtcg tcgtcatcac tcacgaaggg
       61 ccgaaaggtg gaccgggtat gcaagagatg ctttatccta cttcttatat caaatcccgc
      121 catctgggta aggagtgtgc attgattacc gacgggcgtt tcagtggtgg tacttccgga
      181 ctaagtatcg gacatgtttc tcccgaagcg gctgccgnnn nnnnnnnnnn nnnagattaa
      241 ggatggggac attatcgaaa ttgatatacc gaaccgttct atcaatgtga agttgacgga
      301 tgaagagctt gcagcacgcc ttatgactcc ggtaacccgc aaccgtgaag tctccaaagc
      361 attgaaagca tatgccagta tggtgagttc cgctgacaaa ggggctgtga ggctgattga
      421 ttaaaagccc ccctttccga aagcgagggg aggagagaat gaaacaaatt tttcaagcta
      481 ctattgagct tttaaatata atgaatagat aaagtatggc tgataataat aaaaagagta
      541 acttttcctc cctctcccaa ggagagggtc ggggtgaggc tctaataaca ggcgcagaag
      601 cattgatgcg ctctctggag catcagggag taaagactat tttcggttat ccgggaggga
      661 gcatcatgcc ggtattcgat gccttatacg accaccggaa ggaattgaac cacatcttgg
      721 ttcgccatga acaaggagca acccatgcgg tacaaggctt tgcacgtgta tcaggcgagg
      781 ttggcgtttg tctggttacc agtggaccgg gtgctaccaa tactatcacg ggcattgcag
      841 atgccatgat tgacagtacg cctatcgttg tcattgccgg ccaggtaggg acgaacttct
      901 tgggtacgga tgcatttcag gaagtggact tggtaggcat tactcagcct atcacgaaat
      961 ggagttacca gattcgtcgt gcagaagatg tggcctgggc agtggcacgt gctttctatg
     1021 tggcaaagag cggacgtccg ggaccggtcg tgctggattt tgctaaaaac gcccaagtgg
     1081 agaaaacaga atatgcgcct actaaggtgg actatgtccg tagctatctt cccgttcccg
     1141 aaatggagcc ggaggccata cggaaggctg ctgaattaat aaatggtgcg gaacggcctt
     1201 tggtgctggt aggacaaggc gtggagctgg gagaagccca gcaagagctt cgtgctttca
     1261 ttgagaaagc cggaatgcct gccggatgca ctttattggg actttccgca ttacctacga
     1321 accatccgtt gaacaaagga atgcttggta tgcacggtaa cctggggccc aatatcaata
     1381 ccaataaatg tgatgtcctt atcgccgtag gcatgcgctt tgatgaccgt gtgacgggta
     1441 aattggaaac atatgccaag caggcgaaga ttatccactt tgatattgac cctgccgaaa
     1501 tagataagaa tgtaaagacc gatgttgctg tcctgggaga ttgcaaagag acactggctg
     1561 ccgttaccca attgctggaa cccgccaacc atcaggaatg gattgacagt ttccggcaat
     1621 acgaggaagt ggaagaggaa aaggtaatcc gtccggaatt acatccggca ggaaaagcgc
     1681 taagcatggg tgaggtggtg cgtgctgtga gtgaggctac ccataacgag gcgatattgg
     1741 tgactgatgt cggccagaat cagatgatgt ccgcccgtta tttcaaatac agcaaggaac
     1801 gtagcattgt tacttccggt ggcctgggta ctatgggctt cggccttccg gcagctatcg
     1861 gtgccacttt tggacgtccg gaccgcacgg tatgcgtatt catgggagac ggcggcttgc
     1921 agatgaacct gcaggaactg ggtaccatca tggaacaaaa ggctccggtg aagatgattc
     1981 tgttgaacaa taacttcctg ggcaatgttc gtcaatggca ggcgatgttc ttcaatcgtc
     2041 gttattcgtt tactccgatg atgaatccgg attatatgaa gattgcttcg gcatatgata
     2101 ttcctgcacg cagggtaatg acccgcgagg agctggcaaa agcgattgac gagatgatag
     2161 cgactgacgg accgttcctg ctcgaagctt gtgtggagga agaaggaaat gtaatgccga
     2221 tgacacctcc gggcggttcg gtcaatcaga tgttgttgga atgctgaagt catgcgaaat
     2281 taaagaattt actctatcta tggataaaaa actatataca atcattgttc attcggaaaa
     2341 ctttgccggt ttgctgaatc aggtgacggc tgtgtttacc cgccggcaga taaacatcga
     2401 gagtttgaat gtatcggcct cctccatcaa gggggtacat aaatatacca ttaccgcttg
     2461 gacggacaag gataccattg aaaaggtgac caagcagatt accaagaaaa tagatgtgct
     2521 gcaagcccat tatttcacgg atgatgaaat ctatcagcac gagattgccc tttataaaat
     2581 aacgacccct acgctggaag aaaaaccgga ggtgtccaaa gtaatccgta agtacaatgc
     2641 ccgtattgtg gaggtgaatg ctgtatttgc cattgttgag aagaatggca tgagtgagga
     2701 aataaccaat ctttatgagg agttgcgcca gttggattgc gtacttcagt tcgtccgttc
     2761 gggtcgcgta gccattacga ccagctgctt tgagcgtgtc aatgaatatc tggcggaccg
     2821 tgaagcaaaa tatcgtcaaa gtaaacacca ggaatcatga tgagcgagaa caataagata
     2881 ggtacctaca agtttgttgc cgaaccgttt catgtcgact ttaccggacg gctgacaatg
     2941 ggagtattgg gcaaccattt gttgaattgt gcgggtttcc atgccagcga ccgcggtttt
     3001 ggcatcgcga ctctaaacga ggacaattat acttgggtat tgtcccgtct ggctgtcgaa
     3061 ctggatgaaa tgccttatca gtacgaagat ttctccattc agacttgggt ggagaatgtc
     3121 tatcgccttt ttacagaccg taatttcgct atcatcgata aggagggtaa gaagattggg
     3181 tatgcacgtt ccgtttgggc gatgattagc atgaataccc gtaagccggc agatttgctg
     3241 gctcttcata gtggcagcat tgtagattat gtttgcgatg agccttgccc gatagaaaaa
     3301 ccttcgcgga taaaggtggc ctcaaaggaa ccggttgctg ctttggtagc caaatacagt
     3361 gatattgaca ttaacgggca tgtgaacagc atccgttaca tcgagcatat ccttg
//
