LOCUS       c00015_gnlPro..        13689 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OGIECGGG_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 12:41:08
            Original ID  :: gnl|Prokka|OGIECGGG_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13689
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13689
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[199:3689]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      200..3689
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13689
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13689
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(200..967)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 7.2e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.1e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1008..2966)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 4e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(2988..3689)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.5e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             complement(3717..3872)
                     /locus_tag="ctg15_4"
                     /transl_table=11
                     /translation="MRKASSSRNRQQNDNHSKLINSNLFPRLFKNPKSAGNSRRGLPSG
                     LEPGIL"
     CDS             3890..4162
                     /locus_tag="ctg15_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4165..4980
                     /locus_tag="ctg15_6"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARNVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLVLTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5014..5421)
                     /locus_tag="ctg15_7"
                     /transl_table=11
                     /translation="MQSPASLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSPKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5676..6344)
                     /locus_tag="ctg15_8"
                     /transl_table=11
                     /translation="MSLSATANTTLLDSSIVGYSDFTSQTADFGTLKDSVSITSDDSNL
                     TLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSVSWGVGLNTNRKLQ
                     GLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYSNSGLKFGNQQIDQ
                     ILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGLLGLAALMMRRRRA
                     "
     CDS             complement(6414..6503)
                     /locus_tag="ctg15_9"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKRKCIH"
     CDS             6678..7418
                     /locus_tag="ctg15_10"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             complement(7636..7770)
                     /locus_tag="ctg15_11"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGRYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(7882..8082)
                     /locus_tag="ctg15_12"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             complement(8096..9301)
                     /locus_tag="ctg15_13"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPVA
                     GSSLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIIRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9325..10071)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_14"
                     /sec_met_domain="adh_short_C2 (E-value: 2.2e-75, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10200..10718)
                     /locus_tag="ctg15_15"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(10782..12347)
                     /locus_tag="ctg15_16"
                     /transl_table=11
                     /translation="LFRETEMTINWGERVALVGPNGAGKSTLFRMILGEDTPDEGSISM
                     DEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDT
                     FNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDE
                     PTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDF
                     LQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPV
                     ARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGK
                     STLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEA
                     RSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEAL
                     VQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGG
                     ITAE"
     CDS             12515..13222
                     /locus_tag="ctg15_17"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQPYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWDEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPMLVQRIF
                     QSDQQNEAKAAAE"
ORIGIN
        1 ggtttcgtcc ggcattgcca agtacggtct cctggattac tgggtgcctt ccggtgtaac
       61 aattttttac gctgcgcgac gatgaggaag caactgtctg gtattttatt cctggttcaa
      121 ggaaacctgg taatgaaaaa actcccgaca gccgatgccg ccgggagttt ttacagagcg
      181 tcttaagaag gaatcttctt tagaaacaga ggccttcctt ggcgttggcc cgcatgaagt
      241 cgcggttgag gcgggcgatg ttgtccacgc tgatgccttt cgggcaggcg gcttcacatt
      301 catactggtt cgtgcagttg ccaaagcctt ccgcttccat ctgcttcatc atggccagga
      361 cgcgcttgga acgttccggc tggccctgcg gcagcagatt gagatgggcg atcttggcgg
      421 aggtgaacag catggcggag gcgtttttac aggaggccac gcaggcgccg cagccgatgc
      481 aggcggccgc gtcaaaggcg gcgtccgcct tcactttttc cacggcgatg ttgttggcgt
      541 tcggcgcgga accggtacgc acgtcaatat agcctccagc ggcgatgatg cggtccaggg
      601 cggagcggtc caccatcagg tcccgcagga ttgggaaagc cttcgcgcgg aagggttcaa
      661 tccagacggt atcgccgtcc ttgaacttgc gcatgtgaag ctggcaagtg gtcacctggc
      721 gttccggccc gtggggaatg ccgttgatgg tcagggagca catgccacag atgccttccc
      781 ggcagtcgtg gtcaaaatgg atgggttcct tgccttcctt gaccaggcct tcattgacga
      841 tgtccagcat ttccaggaag gaggcgtcca ccggaatgtc cttggcggca taggtctcaa
      901 tgcggccctt ggcttcccgg ttttcctggc gccagacctt gagagtgaga ttgagtgttt
      961 tagccatgtt ataatctttc ttttgagtgt taatgtattg gctatcttta cttgtagctg
     1021 cggatggcaa ggtgcacgtt ctcgaaggtc agcggttcct tgtggagaac aggcaggctg
     1081 tccacgccag tgtattccca ggcggctaca taggcgtatt catcgtcgtt gcgcttagct
     1141 tcgccgtccg gcagctggta ttccacgcgg aagtgggcgc cgcaggattc ctggcggttc
     1201 agggcgtcat agcagagcag ctgggcgaat tccaggaagt cggccacgcg gcaggctttt
     1261 tccagttccg cgttgatgcc gtccgccgtg ccggttacgc gcacgttttc ccagaattcc
     1321 ttgcggagct ggggaatgcg ttcaatggcg tgggtcaggc tttcttccgt gcgggccatg
     1381 ccgcagtctt cccacataat gaggcccagt tcccggtgga aggagtccac cgtcttggtg
     1441 cccttcacat tcaggagctt gttgatgcgt tccttcactt cgtcttccgc agccttgaat
     1501 tccggggcgg cggtggtgac ggcgccgggt ttggtggtcg tcaggtaagc gggcagcgtg
     1561 gcgggaatga cgaagtagcc gtcagacagg ccctgcatca gggcggaggc tcccaggcgg
     1621 ttggcgccgt ggtcggagaa gttggcttca ccgaggacgt gcagcccctt cacattggac
     1681 atgaggttgt agtccaccca caggccgccc atggtgtagt gggaggcggg gtagatcatc
     1741 atgggcgttt catgggggtc gtcgtccgtg atttcttcgt acatgtcaaa cagattgccg
     1801 tattggccgt caatccattc gcgacccatg cgcttgattt catccgcaaa atccaggaag
     1861 acgcccttgc cggtgacggc cacgccgcgg ccgtcgtcgc aggcttcctt ggcggcgcgg
     1921 gaggaaatgt cgcgcggggc caggttgccg aaggagggat acttgcgttc caggtagtag
     1981 tcccgttctt cttcgggaac atcggaaggc ttgatttcct ttttacggat tttttctgcg
     2041 gtttcacggg acttgggcac ccagatgcgg ccgctgttgc ggagggattc cgacatcagc
     2101 gtcagtttgg actggtagtc gcccttgacc ggaatgcagg tggggtggat ttgcgtgaag
     2161 caggggttgg cgaagaaagc accgcgcttg taggccttgt aggcggcagt gacgttgcag
     2221 cccatcgcgt tggtggacag gaagaacacg ttgccgtagc cgcccgtgca gagcaggacg
     2281 gtatcccctg cgtaggattt gatttcgccg gtaaccagat tgcgggtgac gatgcccttg
     2341 gcttcgccgt ccaccagcac cagatccatc atttcatggc gggagaacat ttcaatgtgt
     2401 cccttggcca cttccttttc cagggcctgg taggcaccca gcaggagctg ctggcccgtc
     2461 tgtccgcgtg cgtagaaggt tcgcttgagc tgggcgccac cgaaggagcg gttgtccagc
     2521 aggccgccgt attcacggcc gaagggaacg ccctgggcca cacactggtc aatgatgttg
     2581 gaggagactt ccgccagacg gtagacattg gcttcacggg cgcggaagtc gccgccttta
     2641 acggtgtcgt aaaacaggcg gtaaacggag tcgccgtcgt tctggtagtt cttggctgcg
     2701 ttaatgccgc cctgggccgc aatggagtgg gcgcggcggg ggctgtcctg gtagcagaag
     2761 catttgacgt tgtagccaag ttcggcaagc gtggcagcag cggaggcgcc agccaggccg
     2821 gaacctacca caagcaccgt gtacttgcgc ttgttgttcg gattgatcag tttggactca
     2881 agcttgtact tggaccattt gtcctgaata gggccggagg gaattttggc atccggcatc
     2941 cagtcgctta cgggaaaatt aatcatgact ttgagaggag ttgatggtta tttgatgata
     3001 cccagaagaa ccgagaccgg cacggagatg aagcccaggc agataatcgc gccgtaggcg
     3061 atggcgataa agttgtagaa gggccggatt ttgcgggaat cgacgcccac agtctggaag
     3121 atggactgta ccccgtggcg cagatggctg aacagcatca gaacggccag gatgtagaag
     3181 gcggagcacc atacgttgga aaatccggtc acgatcatct tgtacacgtc aaaggtttcc
     3241 accgtaccgt cggaaatgaa ggtggtgaac tgggcggggt cgtatcctac gcgcagggtg
     3301 tactggtaca ggtggtagat caggaacacc aggacggtca gaccggtata gatcatgtag
     3361 cgggaggaga gcgttgcctt gatggtgttc ttgaacacgt agggttcgcg ggccgcatgg
     3421 ttttccagct tcagctggat ggtcagccag acgtggatga tgaagatcac cgcaagcccc
     3481 gcgcggattc cccagagggc tgcttccggc atggagtgca ggccgtgggc gtaggtgttg
     3541 atccattcag ggcctccgaa gatgagaagg ttgcctgcca ggtgtcccgc aaggaacaag
     3601 accaaacata accccgtcag agccacaatg attttgcggc cgatggagga tgtcacgaat
     3661 gtacatatgg tttttactag tgcattcata ggcgctctaa tgaaataaat gcgtcttcac
     3721 aggatgcccg gttcaagccc ggatggcaag cctcttcttg aatttccggc gcttttcgga
     3781 tttttgaaaa gccggggaaa gaggttgctg tttatcagtt tggaatggtt atcattttgt
     3841 tgcctgttcc ggcttgacga ggctttccgc ataggcgtat cgtctgtgca tgaaaagaag
     3901 taaaaaggaa gtgctggacg cggatttcgc agcggcgcgc gccggcgttc tggatgtggc
     3961 cgcatttctg gaccgggtgg accgcgggga aggggaggcg gatttccgtt accatgccct
     4021 gatggatgtt cttcccctct tatccgcatc cggccccgga cgcgtccggg ccattctgga
     4081 agccctttcc tacagggatg acaccgtgcc ggaaaccgcc gcagccaaag cggcctgcgg
     4141 agccccgaac ctcagcaaat aagaatgatg gctttcatag aacctcatat acatatggtg
     4201 tgccgcacca cggacgaata ccgggccatg gcgcaggccg gctgcctggc ggtaggggaa
     4261 ccggcgttct gggccggtta cgaccgttcg tccgcggacg gtttccggga ttatttcgta
     4321 cagcttacgg aatgcgaacc cgccagggcg gccaagttcg gcatggacca ttacacatgg
     4381 ctgtgcatca atcccaagga ggcgcaggac gtggctttcg cgcggaatgt gatgaagctg
     4441 attccggagt tcattgaccg gcccaatgtc ctcggcatcg gggaaatagg actgaaccgg
     4501 aatacttccc atgaaatgac tatttttgaa gagcatctgg atctggcggt gcgcctcaac
     4561 cagcttgtgc tgattcacac tccccatctg gaagacaagc ttaaggggac cgtaatgatt
     4621 ctttccgccc tgaaaaaccg tccggatctg gacccttgcc gcgtgctggt ggatcactgt
     4681 gaggaacata ccttcccgct ggtgaaggag gccggttact gggccgggct gaccctttat
     4741 cccaccagca agctgaatcc caagcgggcg gcggatattc tggaattgta cggaatggac
     4801 cgtgtctggg ccaattccgc agcggactgg ggggattccg atcccctggt gctgacggcc
     4861 ctggcctgcg agctgcgcag gcgcggtttt tcccggcagg aaacggaacg tcttctcctg
     4921 gaaaatccgg agacatttat gggacagtcc ccgaagttcc ggaaagtgtc gtcccgttag
     4981 ttccgcccgc ggcgcggcgg agggtacggc cctctagtcc ccgtccggga aaaagacggt
     5041 gaggacggcg cccaggatga ccgccgcgtc atccagaagg cccagcctgc cgattccgtc
     5101 aaacaggaat tcgtcgggag tcaggatgta ggcgccggcg gcggccagaa ggcatatatt
     5161 ccgtttgttg aaaaaacgcg gttctccttt tctgcttttg aaataccgga acaggcgcag
     5221 tagcagctgc tgtttttgaa ggttcatgga cgggaacggg ggataaaggt tcaagctcag
     5281 ccattttccc actccttttc cctgtttcgg ggaaggagtc tgttgccgac ggacggaacc
     5341 gcagcgatcc ggaccgtgcg gggaaatgga ttgctgaaag gatgggctgt tccggatgct
     5401 gagggaagcc gggctttgca tgctccggtt ccggctgtcc cggcatggga aaaaggggcg
     5461 tgtacggaag tggggcgggg ccggaagctc ttgaaatgac cctaccgggg gagactgaat
     5521 gccatttttc cgtcaagtgc tggccgtgag gttgccgcag caaatggaag cttttcccct
     5581 ctgttttttc ggcagatgtt tgaacggata aggaaaaggc cggctcacga ttttgtgagc
     5641 cggcctttga atatagggag gcggacggta caggcttatg ccctgcggcg gcgcatcatc
     5701 agcgcggcca gtcccagcag gcccagggaa gccgtggcgg gttccggaat gctggcgatt
     5761 tcactcatca gttgaccaac ttgttcctgg gaaaggaggg agtcgtggat gtagagctgt
     5821 tcgatggatt cagccagtcc tgcgtccatg agaatctgat caatttgctg gttgccgaat
     5881 ttcaggccgc tgttggaata gtacgtagcg ctgtcgccaa aatagatgcg ggtgccaaga
     5941 tctccggtga ctacggaaat ggtcagggac ccttccgtgc ccagcggggt gtcaacgacg
     6001 ggcccgctgt atgaggtgtt gttccataat ccctggagtt tccggttcgt gttcaggccc
     6061 acgccccagc ttacactgct gtttttggcg ttaaacagag cggtataggt ctccggagtg
     6121 ttgattttgg acagatcaag aaccatcgtc acagacataa cgtcgcggtt gttggtaccg
     6181 tatccgttga aggttatccc ggataacgtc agattgctgt cgtcagacgt gatggaaacg
     6241 gaatctttca gggtgccgaa atccgccgtt tgggaggtaa agtccgaata tcccacgata
     6301 gagctatcca gcagagtggt attcgcggtg gcgctcaggc tcatgccggc cgaaagaatc
     6361 agggtggata ataatttctt catggtcagt atcttaataa aatgatgcaa gattcaatgt
     6421 atgcacttgc gcttgaataa cgaatttgga atccgcaagc aattaaaaat attaagagtt
     6481 agtatattgt atttataatt cattgaaaat aatgattttt taatatctct ggtccttttg
     6541 tcaagatgac ggggcaatct ttgttattca ttggtttcat gattgatttg gcctcttttt
     6601 cattacttga cggattccaa atccgattgg ggaattccaa attcgctaca agttgccatc
     6661 caaaaggaat aataaatatg aagaaaacac tgacattttt aatcgcgatg ggaagctttg
     6721 ctgtttcctc ggaggcagcg accgttttta attattacac tcccggtacg gataattaca
     6781 atagtaccat ccatgggttt tatcttggcc tggggtcttc ttccctggct ccttccgatt
     6841 cctcttctcc ctcctccctg tccggagaga tcagactgga cagttttacg ctgcgcggag
     6901 ccgccaacaa tttgggcgct aatgtcactt acggcttcct ggtgctgaat ggctccgaca
     6961 attcggtcat cggctggagc accaatacgg gaactactgc agcagggatt aatctgacgt
     7021 tcagtttttc ttccctggat ggttctcccc tgcttcttga cgcggcattg acataccgtt
     7081 tcctggccgt gagccagtcc gtgatggact tgatgcagga tacgtctaaa acgtatttat
     7141 atgctgcggg gggaacagcc gcccctactg ctaacacgga aggagatacc gtaacgatca
     7201 gcggcggatt gactgctccc ggcatccgcg gccattatga cgccgaggga gcgcctggtg
     7261 attctgtcgt tattacggga gccaacggaa ccaatacttt cagcttatta tccccgattt
     7321 tcacggaaat ccgaggggaa atggtgccgg aacccgccac ggtttccctg ggcctgctgg
     7381 gactggccgc gctgatgatg cgccgccgca gggcttgagc ttcctgatgg cgaaaaatcg
     7441 gcggatgaga gctgttcttg cggaacagct cttgtttttt atatccagag aggaagaatt
     7501 gcttatccgt atgcgggatt tatgccctcc ggaaggtacg gaatttccgg gggcaggggg
     7561 ccgtatccgg ttttttcggc atggcggcaa tttgctggaa acgtttttga gacgcagtac
     7621 cggaaagctt tttctttacc ggaaaatgcc gtcaaattcg gcagcgcgct tttcgtccat
     7681 atggtacacg gcagctttca catagcggcc tttcaggccg gatagggaac ccctttgcag
     7741 ctcacagacc tggagggccg ccgcatacat attattcgcc gtcctattcc ccggcgctgg
     7801 tatttcggaa gaacggcaat gggccccatg cccagcactt catattcttt tccatcgtct
     7861 gccctgatga cggacgttgc atcaacgatg tttcccgacg atgcggctgc cgtggacggc
     7921 gactgcatcc agctccggga tgaaggacgg actgacgcgc atgatatgga gcaggtaatg
     7981 ttcatggcag ccggggacga aatagttcca gaacgcttct ctcgtgacat gttccgtttc
     8041 ggcatggtct gaggattgtt ccgttcttaa tgcaatggtc atgaaaggtt gttctttacg
     8101 gctccccctt ggagaaattc cagaggcggt gcatcgtcat aatgtccgga atgttcatgg
     8161 ggcgcaccac gcggaacccg atcatgcctc cgtccgtcag gtaccagatg cttttagggt
     8221 tttgaggatc ctgacggttc caggcggggg tgctggcgcg gcgcgcagcg cttctcaggc
     8281 tgtccgggtc gtcttcccac gaaccgccgc gaatgatgtg aggggcgccg gggatgatga
     8341 ccaaggggtc tttcgcgggc aagccgctcc gtttgccgta ggcatccgga acgtaagagt
     8401 ccaaaaccca ttccgccaca tttccgtgca tgtcccggag tccccactta tttggttttt
     8461 tagagcctgt tttctgatag cggtcattgg agttgttcca gtaccaggcg tactggtcca
     8521 gagaggcttc cccgtttccg taagaatagg cgccggggga gccggcccgg caggcgtatt
     8581 cccattccgc ctccgtgggc aggcggtagt aatgcccggt ctgggcgctc agccattcgc
     8641 agaatttgct ggcggcgtgg tgggacatgg agatggcggg cagaccgtgt tcatagccgt
     8701 ggcccatgcc caggttcatg gcggtgtagg gggcggtagg ctgcgtaacg gagtcccaca
     8761 gttcgtcatc cggctgttcc tccagaagct ggccgtcctt ggcgcgcgga cgcccgtttt
     8821 ccatgaaggc cgtataaagt tcccagggga tttccgtttc cgagatccag aagggggaga
     8881 tgctcacttt atgctgcgga ccttcgtccg gtttccggtg cggctcttcc gcgggactcc
     8941 ccatgaggaa cgttcctccc ggtatggcga ccatgcgcag ggaagatccc gccacgggaa
     9001 ccgtttccgt gtaggattca aaacgtgccg gatttccgga agcttcaatg agctgatgga
     9061 tttggcgcgt tgtgccgacc agctcccggg acggcaggtc atccggaatg ggaagggcag
     9121 gaccggcagc gcggtccagt tcccgttttt gcagcgcgga tcggctttct ccccactggc
     9181 gtgcgctggt aatgcgcgcg gcatcttccg tggccgggcg gggggaatta ttttcttccc
     9241 ggcacccggc cagcagggcg cttcctccca gaaagcagga aacaaggaaa atgccgcgca
     9301 tggaatggag aaaaccggaa tgccctacat cgtcatgcct ccgtcgcagg caatgacctg
     9361 cccggtgatg taacgggcat cgtcagaggc aaggaaggcc gtcagggcgg cgatatcttc
     9421 cacggaacct tgttctttca aaggtatttt cttaacgatt tcttccttga gattgtcggg
     9481 aatggcattg gacatttccg tggagatgaa gccgggagca atggcgttgc acgtgacttt
     9541 gcgcggagcg aattcctgag ccagtgattt ggtgaaaccg atgaggcccg ccttggaagc
     9601 ggcgtaattg gcctggccga tgttgccgac gagaccgatg acggagctca tgttgatgat
     9661 gcgcccggcc ggggatttca tgagaacgcg ctggagggcc ttgaccgtat tgaacgcgct
     9721 tttcaggttg gtgtccagaa cggcatccca gtcttcctct ttcatgcgga gcatcaggga
     9781 gtcccgcgtg atgccggcgt tgttcaccag gatgtcaatc tgcgggaagt ctttcaaaat
     9841 ggcggccatg gtttcctgaa cggccgcgta atccgctacg tcgcaggggt aggccttgca
     9901 ggaatccgga aattccttgt tgatttcttc tgcggccccc ccgcagctgg atggactgcg
     9961 gctgatcagg atgaccctgg ctccttccga agcgaagcgg cgcgcgacgg cattgccgat
    10021 tccgcggccc gcgccggtaa cgatggctgt tttacctgct aacttttgca tgctgcccac
    10081 agtaaacccg tttttcacgg tttcggcaag cttgaaatgg acttggccgc gcaggaaccc
    10141 atacggggaa ggggcgtgcc gggaatgaaa aaagaggggg ggagaaacgg ggcggggggc
    10201 tactgtccgg cctcttcatt ttcccggagt gcaccggggg gcgccccgtc ttcatccggt
    10261 tctaccaggt cgctgaattc atccgaattt tccaaaatgt cctttaaggc ggcggaaccg
    10321 taatagcggg cctcaaacag gcgtttgcct tcctgcctgc agcggttgtc cagcatttcc
    10381 attcgttttt ccattttttc tatcaaggcg tcttctttct ccttttccgc atcgttcaat
    10441 ttatcctgaa gctggaggaa atgccggatg tccttctgaa tgtcctgcag cgttttgacg
    10501 gcgttgtccg cgctttcctt gtcctgaacg cctgccaacg tctgctggat attgatggca
    10561 aaggaaaagg cctggttgat cagggattcc gcggaaggaa ttttttccgc cggagccgct
    10621 gctgcggggg aagccgttcc ggcggccgtt tcaccaaatg caagagaggc tccggacaga
    10681 agcgcagaat ataagagagg aacaagaaaa gccttcatcc tgttctttta aggcaggatg
    10741 aaatccacgg caaggaaaaa ggggaaactg aaaaaagagc cttattccgc tgtgatgccg
    10801 cctttttcat cgtccagaat gcctgacttt tccagatagt agtcatatcc acctgcgtag
    10861 gcggtgatgg tcccccggtt cacatgcagg gttttttgtg ccagggaacg gatgaagtgc
    10921 acatcgtggg agatgaagac cagtgttcct tcataatgct tcagagcctg caccagggct
    10981 tctacggaca aaaggtccag gtgggtggtc ggctcgtcca tcagcaggag gttgggcgga
    11041 tccaccagga atttgaccag gctgagccgc gatttttccc cgccggaaag aacgctgacg
    11101 cgtttttcca catccagcct ccggaacagg aaggaaccca ggatggaacg cgcttcttcc
    11161 tcccggattt cagcgctgca tttcatgatt tcctccagca cggtattttc cggattcagg
    11221 ttttccgttc gcgcctggga gaagtagccg atgcgcgtcg tggtaccggg agtgcgttgt
    11281 ccggagtcaa tggggatgat gcccgccagg attttgagaa gagtggattt gcccgcgccg
    11341 ttcgggccta caagaacagt gcgctccccg cgttccacca gcaggtccag gttttcataa
    11401 accctgcggt cgccatagga ttggcagact ttttccagct caatgacttt ctgggtgctg
    11461 cgcggaggct gggggaagtt gaatttaaat actttcctgc gggctaccgg tttttgaatg
    11521 attttcatct tttccagctg cttgatgcgg ctctggactt gcccggcttt ggaattgatg
    11581 gagcggaaac ggtcaataaa ttcctgaatg tgcgctattt ccttctgctg gttgcggtag
    11641 gccgcctgaa gctgctcgaa gcgcacgtcc ttttgttgga ggaagtccga gtaattgccg
    11701 cggtattcca ccagttcttc gttgtcgatg tcgtacacgc tttccaccag ctcatccatg
    11761 aaatcccggt cgtgggaaat catcaggatg gctccggggt agtttttcag gtatcgctgg
    11821 agccacagca gggacaggag gtccaggtgg ttggtaggtt cgtccagcat caggaggtcc
    11881 ggctccagga caaggagctt ggccaggtac gcgcgcatga tccagccgcc ggacatttcc
    11941 cgggctgggc gatggaagtc gctttcccga aaggccagcc ctttgagaat tttcttggct
    12001 ttgggctcca gctggtaacc gttggcggcg ttgaaagtgt caatggcttc cgcgtattcc
    12061 ggcgtatccg ttttgttggc gttttccgcc gtccggatgg tgtggatggc ctgttccatt
    12121 tccggcgtga tgcccagggc gatttccaga acggtttcat ccttcggttc gctggcttcc
    12181 tggggaagat agcccacgat ggcgtattca tccatgctga tggagccttc gtccggcgtg
    12241 tcttctccca gaatcatgcg gaacagggtg gatttgcctg ctccgttggg gccaaccaga
    12301 gccacccgtt ccccccagtt aatggtcatt tccgtttccc tgaacaaggt ccgtccggcg
    12361 tgggattttg tgagattttt gatcgtcagc atggtgaaga gaggatgtat tctaccggga
    12421 tggaaagggg aaggcaagag ccgtcagggc ggaggcaggc atttttgaaa gctttactgg
    12481 atttttacgc gtagtttgct agccttggcg cgccatgccg accacgcaga cattcaggct
    12541 tttgcttgct gccgcccttt tgtgcggatg gagttcctgc tgtactcctc cggcggagga
    12601 ttatatacaa caaccttacg tgcagcagca aatgtccggg ctggctaatg ccttcctggc
    12661 gctgctgccg ccggatcagg cctctcttcc cgctgccgga gcggaggcca ggtggctggc
    12721 ggacacggcc gtggtccagt ccgccgcgat tgcccgggac aacaggactg tgctgtttgg
    12781 ctggctgaac aatattctgg tcaattccaa cctgcgcgac agggggctgt gctggcaggt
    12841 ccagcaggat ttgtaccggg acctgcgccg ccgccccgtg aagtatttcc gcatagggct
    12901 gacgattcga gaccgaggaa cgggcaggga gcacagttgc gtgtatgtca atgccgcggg
    12961 gaagggattg cagggctcca ttgttctgga tgcctggaag aactgcgggc atctggtgac
    13021 gctgacccag aaggaccggg aaggcggcaa atgggatgag gactggcggg aaccatttgt
    13081 ttccaaggcc tttccggagg gccattccta cggcatggaa catcacctgg tctggcccgg
    13141 gtgggccagg aaacgcccca tgctggttca gcggatattt cagtccgatc agcagaatga
    13201 ggcgaaggcg gccgctgaat aaaggggaag cctgatccgg caggaaccgg cacacggtgc
    13261 tgcgccgcgg cggtttgcgg tatcctccgt ttttaaggaa aatcccggcg aatcggcaaa
    13321 tggcggaggg aatccggact cagggcaaat aaaaacgcac tcagtgcgta caccgagtgc
    13381 ggattaattg gataatttgc tagtgttgca gggcaaaacc ccgctgcaaa cttacttgcc
    13441 cttggcctgc acaaccggag cgggagcagg agcggtggtt tgctgttgct gctgctgctg
    13501 ggagcaggaa gcgaccaggc aagcggcgcc ggcgatggcg aggatagcga tgttcttcat
    13561 aattcgaatt aaatacagtg tttgttaact actggaacct ccgcatccac ggaggtttgc
    13621 tggcaccaat gtaaatggtg gcaagtagaa atcaagagat tttcttgttc catgtcacgg
    13681 cattacaga
//
