LOCUS       c00059_gnlPro..        13493 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KGGOFMJL_59.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 11:27:56
            Original ID  :: gnl|Prokka|KGGOFMJL_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13493
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13493
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3493](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3493
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13493
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13493
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             2..3493
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_1"
                     /sec_met_domain="PFOR_II (E-value: 6.6e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.3e-82, bitscore: 266.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1e-31, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 3.4e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6.1e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.6e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FSEVAAIYPITPSSTMAEYVDEWAAAGRKNIFGETVLVQEMQSEG
                     GAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAGEFLPCVFHVSARTLASHALCIF
                     GDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATIKSRVPFMNFFDGFRTSHEIQKI
                     EMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAENPDHFFQHRESCNNYYEAVPAI
                     VEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSVTEAAREAIDHLVANGEKVGMVA
                     VHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGEPLYLDVKDCFYGAENAPVIVGG
                     RYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDDVTFTSLPQKEEIALGGEGMFEA
                     KFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDSKKSGGFTCSHLRFGDTPIRSTY
                     LVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIWEGEELAKNLPNKVKKYFAQNNI
                     SVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPVDQAVEQMKKFIVKSYGKKGEDV
                     VNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDPAFINEVVRPINAQDGDLLPVSA
                     FKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCNKCAYVCPHASIRPFVLDAEEQK
                     GAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADICPGNPKKGGKALTMKHLESQLA
                     EADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEFSGACSGCGETPYVKLISQLFGD
                     REMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANSLFEDFCEFGLGMELANEKMRAR
                     LVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKELAEKIIPMVEAAKDKCNHCKQI
                     ADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGKDVNILVLDTEVYSNTGGQSSKA
                     TPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEAYPGPS
                     LIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWRYNPALEEEGKNPFQLDSKEPNW
                     EDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKWRYNSYKRLARENWGADTAE"
     CDS             3618..3806
                     /locus_tag="ctg59_2"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(3817..3921)
                     /locus_tag="ctg59_3"
                     /transl_table=11
                     /translation="MTALEEAQTTERQAARQWMEEHQELVNSWIPEKD"
     CDS             complement(3921..4673)
                     /locus_tag="ctg59_4"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDXXXX"
     CDS             complement(4701..5531)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg59_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 3.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALSWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(5528..6754)
                     /locus_tag="ctg59_6"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7208..8494
                     /locus_tag="ctg59_7"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQPFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSTGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(8457..8789)
                     /locus_tag="ctg59_8"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGVPQ
                     CSRMVGRALKEVPDELSIPCHRVVNTAGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(8817..11570)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_9"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1e-20, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPHFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVAXXXXHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAKPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(11903..13129)
                     /locus_tag="ctg59_10"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 gttctctgaa gtagcagcta tctaccccat cactccttct tcgactatgg ctgagtacgt
       61 agacgaatgg gctgccgcag gacgtaagaa catcttcggc gaaacagtat tggtacagga
      121 aatgcaatct gaaggtggtg ctgccggtgc agttcacggt tctcttcagg ctggtgcatt
      181 gactactact tacactgctt ctcagggtct tcttttgatg atccctaaca tgtacaagat
      241 tgccggtgaa ttcttgcctt gtgtattcca cgtttctgct cgtacactgg cttctcacgc
      301 attgtgtatc ttcggtgacc atcaggacgt aatgtcagct cgtcaaaccg gcttcgctat
      361 gttggcagaa ggttctgtac aggaagttat ggatttggca ggtgttgctc atctggctac
      421 tatcaaatca cgcgttccgt tcatgaactt cttcgatggt ttccgtactt ctcacgaaat
      481 ccagaagatc gaaatgttgg aaaacgacga cctcgctccg ctgatcgacc aggaagcttt
      541 ggctgaattc cgtgcccgtg cactgaatcc gatgaagccg gttgcccgtg gtatggctga
      601 aaaccccgac cacttcttcc aacatcgtga atcatgcaat aactactatg aagcagttcc
      661 tgctatcgta gaagaataca tgaacgaaat ttccaagatc acaggccgca aatacggttt
      721 gttcgattac tacggtgcag aagatgcaga acgcgtaatt atcgcaatgg gttctgtaac
      781 tgaagctgcc cgcgaagcta tcgaccactt ggtagcaaac ggcgaaaaag taggtatggt
      841 tgccgtacac ttgtatcgtc cgttctctgc taaacacttc ctggctgctg tacccaagac
      901 tgcaaagagc atcgcagtgc ttgaccgtac aaaagaaccg ggtgctaacg gcgaacctct
      961 ttaccttgac gttaaagact gcttctatgg cgcagaaaat gctcctgtta tcgttggcgg
     1021 tcgctacggt ctgggttcaa aagataccac tccggcacag atcatctctg tattcgaaaa
     1081 cttggctatg ccaatgccga agaaccactt cactatcggt atcgtagacg acgttacgtt
     1141 cacttctctt cctcagaaag aagaaatcgc tctgggcggt gaaggtatgt tcgaagctaa
     1201 attctacggt ctgggtgctg acggtacagt aggtgccaac aagaactctg ttaagattat
     1261 cggtgacaac accgacaaac actgtcaggc ttacttctct tacgactcca agaagtcggg
     1321 tggtttcact tgttctcact tgcgtttcgg tgatactccg atccgttcta cttacttggt
     1381 aaatactccg aacttcgttg cttgtcacgt tcaggcttac ctgcacatgt acgacgtaac
     1441 acgtggtttg cgtaagaacg gttctttctt gctgaacacc atctgggaag gcgaagaact
     1501 ggctaagaac ctgcctaaca aggtgaagaa atactttgca cagaacaaca tctctgtata
     1561 ctatatcaac gcaactcaga ttgcaatgga aattggtttg ggcaaccgta ccaatacaat
     1621 ccttcagtct gcattcttcc gtatcacagg cgtaatccct gtagatcaag ctgttgaaca
     1681 gatgaagaaa ttcatcgtta agtcttacgg caagaagggt gaagacgttg ttaacaagaa
     1741 ctacgctgct gtagaccgcg gtggtgaata caagactctg actgtcgatc ctgcttgggc
     1801 taacctgccg gatgatgcaa aagcagaaaa caatgatcct gctttcatca acgaagtagt
     1861 tcgtccgatc aatgcacagg acggtgactt gctgccggta tctgcattca agggtatcga
     1921 agacggtact tggtatcaag gtacttccaa atacgaaaaa cgtggtgtag ctgcattcgt
     1981 tcccgaatgg aatgctgaaa actgtattca gtgtaacaag tgtgcttacg tttgtcctca
     2041 cgcttctatc cgtccgttcg tactcgatgc tgaagagcag aagggtgcta agttcgagca
     2101 actgaaagct gtaggtaaag cattcgatgg tatgacattc cgtattcagg tagacgttct
     2161 cgactgtctg ggttgcggta actgtgccga catctgtccg ggtaatccga agaagggtgg
     2221 taaggcattg accatgaaac accttgaaag ccagttggcc gaagctgata actggactta
     2281 ctgcgctgaa aacgtgaaga gcaaacaaca cctggtagac atcaaggcta acgtgaagaa
     2341 ctctcagttc gcaactccgt tgtttgagtt ctcaggcgct tgctccggtt gtggtgaaac
     2401 tccgtacgtg aaactgattt ctcagttgtt cggtgaccgt gaaatggttg ctaacgctac
     2461 aggatgttct tctatctact ccggttcagt tccttctact ccgtacacta tgaacgaaaa
     2521 gggtcacggt cctgcatggg ctaactcctt gttcgaagac ttctgtgaat ttggtctggg
     2581 tatggaactg gctaacgaaa agatgcgtgc ccgtctggtg aaagtaatga acgaagctat
     2641 cgcttctgat tgctgcccgg ctgaatacaa agaagtattt gctgaatgga tcaacaatat
     2701 gctggatgca gaaaagacta aggaactggc cgaaaagatc attccgatgg tagaagctgc
     2761 taaagataaa tgcaaccact gcaagcaaat cgctgatctg caacaatatc ttgttaaacg
     2821 cagccaatgg atcatcggtg gtgacggtgc ttcttatgat atcggttacg gtggtcttga
     2881 ccatgtaatc gcttccggta aggacgttaa catccttgta ttggatactg aggtttactc
     2941 taacacaggt ggtcagtctt ctaaagctac tccggtaggc gctatcgcta agtttgctgc
     3001 tgcaggtaag cgtgtacgta agaaagacct cggtctgatg gctactactt acggttatgt
     3061 atatgttgct cagattgcta tgggtgctga ccaggctcag actctgaaag ctatccgtga
     3121 agctgaagca tatccgggac catcactgat catcgcttac gctccgtgta tcaaccacgg
     3181 tctgaaagcc ggtatgggta agagccagga agaagaagaa aaggctgtta agtgcggtta
     3241 ctggcacttg tggcgttaca accctgcttt ggaagaagaa ggcaagaatc cgttccaact
     3301 ggatagcaaa gaacctaact gggaagactt ccaaggtttc ttgaagggtg aagttcgtta
     3361 cgcttctgta atgaaacaat atcctgctga agctgaagaa ctgtttaaag ctgctgaaga
     3421 aaacgctaaa tggcgttaca acagctacaa acgtcttgcc agagaaaact ggggagctga
     3481 tacagctgaa taataagtag aaatactttg tacataataa aaggcaggaa tcctggaaac
     3541 agattcctgc cttttttgtt tatatcttag aagtaacgat tacttctcac gaagatattc
     3601 attaaaactc taaagatatg atcggatttg ttatttggat tatcggtttg atactgactt
     3661 tcagagctgc catagagatt tggaatataa atgcggctgt agagaaaaga cttatagcga
     3721 ttgtattaat cgttcttacc agctggctgg gactactttt ctactacttc tatggtaaag
     3781 aaagaatggc gggatggttg aagtagtgtt tgcatatcaa tctttctcag gaatccaact
     3841 gttcaccagt tcctgatgtt cttccatcca ttgacgggca gcctgtcttt ccgttgtctg
     3901 cgcctcttcc agagcagtca ttaannnnnn nnnncatctg tcagacgaat gttgcccaaa
     3961 agttcggcag caaaagggtc tttctcgcta aaacctttcc atgctatggt atgaatggat
     4021 tccgtatttc catatatcag cttcgggtcc tgaagaactt tcagcttgaa acggtcgaac
     4081 atccagtgag gcgtccatcc cgtcacgaca atccagtctt tcttatcaat cgctttcttt
     4141 agggaagcag tcatggcagg tccgctcgaa gtcatcagtt tataatccaa tccatagtct
     4201 ttgatggcct gatcggtagc tttcataata ccggctccgg catcaatacc gacaatctga
     4261 ccggagaaac gttccttttc cgcgttcagt tcttcgattg agttgatcgt aacgtaatcc
     4321 ggaaccacca gcccgatacg ggcaccatca taaatatccc cgataacttc gagtttatcc
     4381 ccgtattgtt tcatataatc ttccatagtg acaggcatcc agacatccat aaatacgtct
     4441 gctttcttac gggagataga ggtaaatata ggtgcaaggt cggcattcag caactttaca
     4501 tcgtacccct gatcttcaaa aatcgctttg gcaaggtttg tcattgcaat accttccgac
     4561 cagttggcat aagcgatact tatcttctta ctctttccgt tgtctccgca ggaaacgaag
     4621 gttaagagta tgccggcaat aaacattgcc gcaatcattt ttatcttatt cattgattat
     4681 tcctttcttt ggtgtgattc ttatttcttt ttactttttc tgttatctgc cataccctga
     4741 gtgatgcggt ccagcacgat cgccaatatc acgactgcga taccgccttc aaatccgagt
     4801 ccgattttca tttgggtgat acctttcagc acgatttctc ccaatcctcc ggcagaaatc
     4861 atggcagcaa tcactaccat cgaaagtgac atcatgatcg tctggttgat tcccgtcaga
     4921 atagtaggca acgccaaagg caattgcacc ttataaagaa gctgccaggg agtagctcca
     4981 aaagagcggg aggcttctac tacgttttta ggaacctgac gaatgcccag accggtcaga
     5041 cgaaccacag gaggcattgc aaagatgatg gtggcaaaag ctcccggcac agttcccaat
     5101 ccgaagaata gaacggcagg aatcagatag acaaaggcag gcattgtctg cataaagtcg
     5161 aggacagggc gcattatctt gttacaacga tcactgttgg cagtccagat tcccaacgga
     5221 acgcctaaaa gcaatgccag acaagtggaa gaaagtacca atgccaatgt ctgcatcgtt
     5281 tcttcccaaa agcccatgcc gtaaataagc aataaaccca agagggtaaa tacggctgtc
     5341 cccttacccg acttaaacca ggagagcgca gccagcactg caattgtgat ataaaaaggt
     5401 attccaaaca gtacgtgctg aaaaccgtct atgaatcctc cgatccccat gctgagagca
     5461 tcaaaaaagg aagcaaaatg ttctgtgagc caattaatgg cagtctctat atattgtccg
     5521 atatttatca taattctatt gcgttttgaa tgatttcatt aatttcttct ttatcttttc
     5581 ccgttacttc gatgatcaat gaggaaagtg gcactacgcc ttcaaactcc cgattctcat
     5641 ttacgaccca gattggcgag ttcgtttttg tcatcaacgg aagaatatct tccagcaccg
     5701 tatcacccag cactgaatga acttcatgcc ttactacgga ctcgatggag cggatttgct
     5761 cttttcgtag tttcagcaag tcattcaacc gcacctctcc tactaacaga ttattggaat
     5821 cgactaccgg aagaacggtc agattccgtt cgcgcatctt acggatcagc acctccgggc
     5881 cttctttctt caaacgtgcc actatgggtt tatctaccat aacagaggaa gctgttataa
     5941 tcttgcttcg atctacattc tccacaaatc gttctacata agcgttggca ggttcggtca
     6001 ggatttcttc cgatgtaccg atttgtacaa tttctccatc cttcatgata gcaatccggt
     6061 cacccaattt aatcgcttca ctcaggtcgt gagtaataaa gacaatcgtt tttttcatct
     6121 tcgactgcaa agtcagcagt tcatcctgca tctgcacacg gatcaaagga tcgagtgccg
     6181 agaaggcctc atccatcaac aggacttcgg gattattggc caaagcccgc gccagcccga
     6241 cacgctgctg catcccaccc gacagttcac ttaccatctg attctcgtag cctttcagcc
     6301 ccaccagttg catgctttcc atcgctttct gctcccgttc tccctttttt actccctgta
     6361 gttcgagccc gaaagctata ttatgcaaga cagaacggtg aggaagcaga ccgaagttct
     6421 gaaagaccat agccagttct ttccggcgaa tctgcaacag ttccttatcc gacactttgg
     6481 ctatgtctgt tccattgata atcacttctc cggaagtagg gcgtatcaaa cggttgatgc
     6541 agcggagtaa agtggacttt ccactaccgg acagccccat aatgacgaat atttcgcctt
     6601 cattaatgga aagattcgca tctttcaccg caactgtaca tccggtcgct ttcaatattt
     6661 cactttttgt tttaccttct ttcaacatct tcaaagcctt ctgcttctca ttgccaaaaa
     6721 ccagatagag atctttaatt tctattttac tcatacaata aaatggttta ggttattaaa
     6781 ataatataca cagcaagaca agaacaaacg ataacaggaa tnnnnnnnnn naaatacggg
     6841 acaaataaca atgaatcccg aaataattaa tagaatgatt attgacagac tgagtaatta
     6901 aaaaaggaat agaatttgat aagataatcc tttcaacgaa tagcaaaaaa atagcatttt
     6961 tatgtataaa aacagcctgt tccagtatct tgctggcaca aagatacaaa aaacagatta
     7021 aacatgcaaa ttatattcaa aatccggggc atacagaggg ctttatttgt aatgatatgg
     7081 aaagttttcg ggtaatattc ccctatcact cagcaaaata gaacaaaccg gcagataaat
     7141 ataaaataag tttgaatatt tcacctaaac accgtatatt tggcgtcaat aactaaacta
     7201 gatttatatg ttcaacaggg ctattacaat tttcctgggg aaggataatt gtcattacac
     7261 aacaaaagaa aaacaaacag gtactgccac actagacgac aaaagccaag tacagttcct
     7321 tagtaaaaag aaccccaaaa tgccgttttt ctatagtcgg cggaatctct acatgatagg
     7381 tttcctgctc gcttttatag tgactctgct cgaatttatg cgaggacggc atcaaaactt
     7441 tatggtcttc tcagacgcta ctcaattctt ctggcaaggc atcagcccat acacaaccga
     7501 atttgtagaa gctcacggac gctacttcct ttattctcct gttttcacgg tattgttcgc
     7561 tccgtttgcg tatctgcctg catggctggg acctttcgcg tggaatctat tcaattattc
     7621 attgtttttt gtagcgatct tcacgctgcc ccaaccattc acccagcagc agaaatgccg
     7681 tatgttcctc tttctgttac tgattttagg acaaagttta ctttcatttc agtataacat
     7741 aacggtagcc tatttattct tattcgccta tacgttattg gaaaaagacc gtggatttct
     7801 ggctgttctg ttaatcatga tttcgggatg taccaaagta tatggaattt tcgaactggc
     7861 attgttgctg tgttatcctc acgtatggcg taactttggc tatgccgttg caatgggcat
     7921 tgtattgctt gcgttaccgt taatcaaaat agctcctgca gatttgctcc cctattatga
     7981 agaatggtgc catagtcttg ctgttcatca atccaccgga gcttatgatt catttttcta
     8041 tgcccgcccc attgcagcat ggacattgcc acacttccgt gcacttcaga taggaatgct
     8101 cggtctgctg actctgctct ttttggggaa tttccgcaaa tggtcgtctt ttgccttccg
     8161 tgcccaagct ttgggcattc tcatgggctg ggtagtatta ctgagtgact ccgccgagaa
     8221 gcatacctat attatcgcat tggcaggttt catgctctgg tattggagca gaccaacacg
     8281 taccgcaaca gacaagattc tattttggtg ctgttttgtg ctgttatgta tcgttcctat
     8341 cgacatattc gtccctgtac ccatcagaga tttcattacc aggaccttat ggcttcatgt
     8401 atgggttttc tttattgtat ggatacggat gatatggctt accttccttg catccttcat
     8461 tcatccacgt gccacaaatg ttctttcaga ttaacgcatc cgttagcttt gaaagaaact
     8521 tcttctgcca gcaagagttg tttttgttcc acccaaccgg gcaccagcct tccggcggta
     8581 tttacaactc tatggcaggg aatggataat tcatccggca cttctttcaa tgcacgtccc
     8641 accatccgcg agcattgggg tacccccaac aacaaagcaa tacctccata ggtagatact
     8701 tttcccacag gtatctggga tacgacttcg tacacttcct tccgaaagga ttcggaaaag
     8761 ctctctttat ctactttata atctttcata tatccctctt tacgatatca atgaaatcat
     8821 cctttccttt tcaggaaatc tgtcgggctc tctccaaact gctctttata gcacttggcg
     8881 aaataagaag gtgaactgaa accgacttca taaccaatct ccgctacggt catgtccgaa
     8941 gaagcaagca aagaagctgc cttcttcaaa cgggcgatac ggagcaattc attcggagag
     9001 tagttagtca atgatttaat cttgcgataa agctgcacac ggcttagtcc catgtctttg
     9061 cccaagtcct ccacattcaa accggagtct cccattttct cttcaatcaa tgacttgaat
     9121 ctttctacaa aatccttgtc catatcgcag acatcttctt ttgccaatgt ctgcccgtca
     9181 ccaaagaact gtttcagacg acggtgagaa tcaatcagat tgcggacacg tgccagcaac
     9241 agctgtgaac tgaacggctt tgaaatataa gaatccgcac caccgtcata tccctgaata
     9301 cgctgttcgt ccagtgaaca cgctgtcagc agaataaccg gaatatgaca ggtctgtaac
     9361 tcacttttca gccggcggca acattcaatg ccatcaatgc ccggcatcat cacatcagaa
     9421 atgatcaggt ccggaacata cttcatagcc ttacggattc cttcggagcc gtctgccgct
     9481 tcaatcaccg tatagtctgt atgcaacaac gtatggacat acgaacggat atcctcatta
     9541 tcatcaataa tcagtacgga cggtttggaa gagtcatatc ctttttccag ttcttcctct
     9601 tccgccaata gaacatctgt tgtacgggaa tccgcagaaa caagggtggt atccggtttg
     9661 gcagcaacag cctcacaaga ctgtacaggc agttcaacgg taaagaccgt gccctgtttc
     9721 tcatcgctct ctacggagat cataccaccg tgcatttcta cgaaggcttt taccaatgcc
     9781 agtccgattc ccgaaccggt atggtgcata tcgatcttat agaaacggtc gaatacattg
     9841 cgaatatgtt cggcagaaat catggaaccg gtatttgcca ccgtgaaacg tatccatcgc
     9901 ttgtcctctt tactaaggga agacagacgg acggctattt tcccgttttc cggtgtaaac
     9961 ttaaaggcat tggacagaag attgaaataa atacgttcca gcttctccat gtctgccagt
    10021 gtatgataat ccgtatccgg catactatca aaagaaaaat ggatatgctt cttacgggct
    10081 gccgcctgaa aagactcatt ccatccttcg aaagaagaaa ggacatccac cgtaaccgga
    10141 gtatattcca tcttgccgtt ttcatattta cggaaatcca gaatctgatt gaccagacgc
    10201 agaaggatat tcacatttcg ctgaatcagc atgagcatcc ggtgctgatc tccactcaat
    10261 gtcttgtccg ccaataaatg ttnnnnnnnn nnggcaacca atgtcaacgg agtacggaag
    10321 tcgtgagaaa tattggtgaa aaagaccagc ttggcatggg tagcttcttc cagttgatga
    10381 gagagctgta tcaattggtc acgctgttct tccagtttgt cacgctgctc ttccaattgc
    10441 tgcttctgct taaaaagctc tttattcaag cgattcttag agcggagtga tttataaacg
    10501 accaataata aaccggctac caataaaagg ataatcagac tgccgtataa aacaacctgt
    10561 tgtgtagcta cctgagagag gtatccaccg atacgtccgt tgagcgtttc aatcttttta
    10621 tcgagttcgg agatgtgtgt agtctgcaac tgcatgacgt gtgcgttggt acggtccaca
    10681 acagcggtat tcatcactgt ttctttggga tagggtttct tctccagaat gtccatagcc
    10741 agttgcagta ccttatcgcc attggtcgga tagataaagg tggcatccag cacactgtcc
    10801 aaaaccagtt ccagtccgtt tcccttaccc ggcaaggcat ctatgccgac aaaaatcatt
    10861 tccttctccc gccctgccat ctttgctgcc tgataggcac ccggagcgat acggtcatta
    10921 tgggcataca cagcatcaat cttaggatgc ctccgaagca tactatccat ttctatctct
    10981 gccggaccac gttcccacgc agcatccgct ttatcaatca gctttatatc cgggaattta
    11041 ctgatggcag ccataaatcc ctgatgccgt tccattgcag gagtcgaacc gctcaatcct
    11101 gtcagttcta ctatatttcc cttccctttc agactggagg caatatagtt tcctaccgaa
    11161 cgaccgattt cataattatc ggctccgata taggcagtat atttatccga aagaatcttc
    11221 cggtctacaa gaataacggg gatgcctttc tgataagctt cttctacaat cggagtcata
    11281 ggagcagctt cgttagcgga aataatcagc agatcgactc cttcgtccat aaaataatgg
    11341 acatcttccg cctgcttact gttatcatct cctgccgaac ggatttccac cgaaacgcca
    11401 ttataaaaca ttgcttcccg aagaatctca tcattcatct tatgtcgcca tgaatcatcg
    11461 ctgcattgag ccaccccaat acgaaaatgg ggtgtatcct gccggcaagc cgtcatcccg
    11521 attaaaccaa acagcaccag catccacttc agatatctca tcgtcttcat ccatctcatc
    11581 atttcatagt tctttctgta atccaattaa gaacaaaaat aagaaataat actgtaaagt
    11641 tctctaactt cagctattta ttattctaaa aagaaggaaa gcagtcctct ttcagaccat
    11701 cggaaagtat taacaaaagt ataaagcgta aaacaaacac ttaatcaatg ttataaaaca
    11761 tagcgtttta cttggataat ttgcagattt cacagaagtc cgtatctttg cactgtgttt
    11821 ttcatagtat tagatttaag gttaacaaag gttggagcaa ggcgttgctc ctttttttat
    11881 gccctgacct ttcatctacc ggttagtttt catcccattc cttttccagt ttaccatcaa
    11941 tagtgtagcg tttccatcgt cctacacggc gaccattctt atattcccca cattcacgaa
    12001 gctggtcatt ctttacataa cgagcttcga acggtccgtt ctgccttccg ttcacatagg
    12061 tagaagtttc ccaataatca aagcggttgc tcactatcag ccgtcgttcc ttgccatgca
    12121 atctgccggc ctgataggta gcttcatatc tcaattcacc attttccaga ttatattcac
    12181 ggtataaacc gtctttacga tcgttcttca tataatattc tttctgcctt accccacttc
    12241 cgttggcaaa tgagacatgg agtccatctt cttttccatc cagataggtt tcaatcatca
    12301 gcgtatctcc gctttcagca aaagtagtcc accgaccatt cttctttcca ttcttataac
    12361 tacccagtat acgtggcgag ccaaacgtaa acacggacga atattcaccg tcctgcaaac
    12421 cttcttcatt gaaataaacg gtctcataca aatcatatgt acctttcaga aaagtatact
    12481 gtttgcctac ctgcttcccg tccttgtaat tatgctcttt ccgcaaagta ccgtcagatt
    12541 cgtacgacag ttgcttcccg tgctctttcc ccatccggaa gtttctttca ctttccactt
    12601 ttccggtagt aaagtaactt ttgctcgtac cgtccagctt accttcctta taggactttt
    12661 cttctttcag cttaccgtca aacttggagt taatcttgaa gaggccatcc ttccgccctt
    12721 ctttataact tccttccgtt attaatatat tgtccacata ttctttgtat ccgccatcat
    12781 aaaaaccatc tttaaaagat gccagcacat aggcggaatg ataaccatct atgatgcgat
    12841 gttcgccatt caatgctttt tccgttttca gttcctgaaa caacagtctg ccatcgccta
    12901 cattaacaac agatacctga tcgatcttat attccttttg cgcaaacaaa ggaagagcaa
    12961 gatataaaaa caaaaatacg ttccagcttt ttgatctgag gaagttcgaa atgtgtttca
    13021 taaagtagtt ttctcttttt gatttattat ttaaaaacct gccgcaaaga taggcaatcg
    13081 gcttataaaa caaggcaagg aagaggggga caattaaaaa aaagaacatc tgttattatc
    13141 attctaataa ttaacagatt aagtagtaaa tcaaaacaca gggaaggggg acatttactg
    13201 aaataagaaa cagaaaagaa gatgtgtcaa aagcaactaa attcccctcc ttcaggaagg
    13261 aggagagttt agttgctttt gacacatctt ctttttgaat ttaaagagat tctacaacaa
    13321 tctgtctttc agaacaaccg gaagttcggg cattgcaccg ctctgcgtac aaacataagc
    13381 ggaaacttcg acagccagct tatgagcttc gggaacagac ttgccattca gaatggaagc
    13441 acagaaagcg gcagtaaagg aatcccccgc tcctaccgta tcggctaccg gaa
//
