LOCUS       c00037_gnlPro..        16877 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCAOOAJM_37.
ACCESSION   c00037_gnlPro..
VERSION     c00037_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 17:00:56
            Original ID  :: gnl|Prokka|KCAOOAJM_37
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16877
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16877
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3319:6877](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(3320..6877)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16877
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16877
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             46..1281
                     /locus_tag="ctg37_1"
                     /transl_table=11
                     /translation="LYCMSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVA
                     VKDANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQ
                     IRRKELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQM
                     VSELSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVF
                     ITHDLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSV
                     MVDKPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSI
                     ESVVRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKE
                     EINEIIQNAIEL"
     CDS             1278..2108
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg37_2"
                     /sec_met_domain="BPD_transp_1 (E-value: 8.1e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             2136..2996
                     /locus_tag="ctg37_3"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(3007..3195)
                     /locus_tag="ctg37_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(3320..6877)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_5"
                     /sec_met_domain="PFOR_II (E-value: 1.4e-18, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2.2e-31, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 7.1e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.3e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 3.4e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(6911..8020)
                     /locus_tag="ctg37_6"
                     /transl_table=11
                     /translation="MDEIDWSDRLIGIKGTRGVGKTTFLLQYAKEKFGTDRSCLFINMN
                     NFYFSGHSLVDFANEFQKRGGKVLLIDQVFKHPEWSKELRMCYDRFPSLKIVFTGSSVM
                     RLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFRAYSLEEILSTHEQIAKGVLSKVR
                     PLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVEVDILLIKQIELKYLSKIKKLLYL
                     LAVDGPKAPNVSQLASDVQTSRATVMNYIKYLADARLINLVYPKGEEFPKKPSKIMMHN
                     SNLMYSIYPVKVEEQDVLDTFFVNTLWKDHKVHKGDKNVSFMVDEVMPFKICAEGTKIK
                     NNPDVTYALQKAEIGRGNQIPLWMFGFLY"
     CDS             complement(8167..8631)
                     /locus_tag="ctg37_7"
                     /transl_table=11
                     /translation="MRMLSQNIHIIRRRQLRLTCPQCHQTLPQSRVPTPRRELPVFTVS
                     HFRFRQQGHIHAQKFTLCFQEVRIISRRCKHRTSRFGIPHRKQRQVTRHLSGGSRRHIV
                     RLTACQRHIMLRIEYINRSFRHVKDGFNTLFCKYIQEIIRNLHNKEKLIN"
     CDS             8788..9450
                     /locus_tag="ctg37_8"
                     /transl_table=11
                     /translation="LNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYAD
                     GRGRVVFAGYSVFHTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSAL
                     FGGFYHGYLGVDMMICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVF
                     RIDYYPLAGQALEEHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             complement(10012..11439)
                     /locus_tag="ctg37_9"
                     /transl_table=11
                     /translation="LFLIFPAKAQPKHEVRAAWITAVYGLDWPRTRATTPQGIRKQKEE
                     LVDILDKLKAANFNTVLFQTRTRGDVLYPSSIEPFNSILTGKVGGNPGYDPLAFAIEEC
                     HKRGMECHAWMVTIPLGNKKHVASLGKQSVTKRVKDICVPYKNEYFLNPGHPATKEYLM
                     RLVREVVERYDIDGVHFDYLRYPENAPLFPDKYDFRRYSKGRTLDQWRRDNISEIVRYI
                     YKGVKAMKPWVKVSTCPVGKYRDTSRYSSRGWNAFYTVYQDPQGWLGEGIQDQIYPMMY
                     FQGNSFYPFALDWQEQSNGRQVIPGLGIYFLHPDEGKWTRDEVDRQINFIRNQKMAGEG
                     HYRVKYLMDNTQGIYDELIENFYAYPALQPPMTWLDNVPPSAPSALKVTSIDNGYTELN
                     WQPATDNDQRNKPMYVIYASNEYPVDTKKAENIVAQSIRETSYIYAPIQPWNAKKYFAV
                     TAIDRCGNESAPINGDK"
     CDS             11787..13178
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.9e-17, bitscore:
                     55.2, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLAEMLGDDYEVTKFGKGSSGVFIKLREDATTPENPNEYQFAYI
                     NSEQCAAALEYKPNIVIIKFGANDANKKNFEKYGKETFKADYKKLIAKFQALSTKPDIY
                     ICTPPPMYYGDGGFLGSFDDNVAKNYIQPAVREIAEELNLVCVDLYNPLKGHPEFMPGG
                     NDWVHPDHRGHYIIAKEVYKAITGEFVMNPGGITVAASDISLSGSKAKMKNGAIEKAKN
                     GTRLSFDVHFGSLPTYEKVEVDVQLNKKKSGYLDFYLDTETIPFASVDVSGADSKNFTT
                     QSALFDRRIKGKHKVTVQWRGQDAKLKSVTIKEKYMPYVTDNVSQVYLVNKATGMVLDC
                     NPDSKVISAAKYDSEKKSQLFCIENLTYHILRVRNIATNLHVMNNGDKVIVGKPGDDWR
                     VHDPKYALFLTPTDDEGYYSLELSPEARIGLSSANSTEVVGNRSGQIEDLDKWKIVTAD
                     EMKKQ"
     CDS             13411..14841
                     /locus_tag="ctg37_11"
                     /transl_table=11
                     /translation="MITFTLCLLALIAGYFTYGRLMERVFGPDDRKTPALTKADGVDYI
                     PLPTWKIFMIQFLNIAGLGPIFGAIMGAKFGTSSYLWIVLGSIFAGAVHDYFAGMLSLR
                     HGGESLPEIIGRYLGLTTKQIMRGFTVLLMILVGSVFVAGPAGLLAKLTPESLDATFWI
                     VVVFLYYILATLLPVDKIIGKIYPLFAVALLFMAVGILVMLYVNHPALPELWDGLQNTN
                     PDASELPIFPIMFVSIACGAISGFHATQSPLMARCMTSERHGRPVFYGAMITEGIVALI
                     WAAAATYFFHENGMEESNASVIVDAITKDWLGAIGGVLAILGVIAAPITSGDTAFRSAR
                     LIVADFLGLEQKSMRRRLYICIPMFAVAIGLLLYSLRDADGFNMIWRYFAWANQTLAVF
                     TLWAITVYLVVAKKPYWITLIPALFMTSVCSTYICIAPEGLGLSHIVSYCIGIGCVVVA
                     IAWFFIWLGKQKTRKLSE"
     CDS             14838..15068
                     /locus_tag="ctg37_12"
                     /transl_table=11
                     /translation="MKKIKKSTGVAIAFLIYVSVTAAYLLPRNTEVGQTEKILTVVGSY
                     VIVLLLWLVLRKKEQMRERRKKDEQSIHLKK"
     CDS             15073..15558
                     /locus_tag="ctg37_13"
                     /transl_table=11
                     /translation="MKKLALAICLLVVSIAAQAQFEKGKMILNPSVTGLDFSYSKNDKA
                     KFGIGAQAGTFLADGIALMVNVGADWSKPVDEYTLGTGMRFYFNSTGVYLGGGLDWNRF
                     RWSGGHHQTDWGLGIEAGYAYFLSRTVTIEPAVYYKWRFNDSDMSRFGVKVGFGFYF"
ORIGIN
        1 tttgttcttg ttttgctgtg tatattattt taataaccta aaccattgta ttgtatgagt
       61 aaaatagaaa ttaaagatct ctatctggtt tttggcaatg agaagcagaa ggctttgaag
      121 atgttgaaag aaggtaaaac aaaaagtgaa atattgaaag cgaccggatg tacagttgcg
      181 gtgaaagatg cgaatctttc cattaatgaa ggcgaaatat tcgtcattat ggggctgtcc
      241 ggtagtggaa agtccacttt actccgctgc atcaaccgtt tgatacgccc tacttccgga
      301 gaagtgatta tcaatggaac agacatagcc aaagtgtcgg ataaggaact gttgcagatt
      361 cgccggaaag aactggctat ggtctttcag aacttcggtc tgcttcctca ccgttctgtc
      421 ttgcataata tagctttcgg gctcgaacta cagggagtaa aaaagggaga acgggagcag
      481 aaagcgatgg aaagcatgca actggtgggg ctgaaaggct acgagaatca gatggtaagt
      541 gaactgtcgg gtgggatgca gcagcgtgtc gggctggcgc gggctttggc caataatccc
      601 gaagtcctgt tgatggatga ggccttctcg gcactcgatc ctttgatccg tgtgcagatg
      661 caggatgaac tgctgacttt gcagtcgaag atgaaaaaaa cgattgtctt tattactcac
      721 gacctgagtg aagcgattaa attgggtgac cggattgcta tcatgaagga tggagaaatt
      781 gtacaaatcg gtacatcgga agaaatcctg accgaacctg ccaacgctta tgtagaacga
      841 tttgtggaga atgtagatcg aagcaagatt ataacagctt cctctgttat ggtagataaa
      901 cccatagtgg cacgtttgaa gaaagaaggc ccggaggtgc tgatccgtaa gatgcgcgaa
      961 cggaatctga ccgttcttcc ggtagtcgat tccaataatc tgttagtagg agaggtgcgg
     1021 ttgaatgact tgctgaaact acgaaaagag caaatccgct ccatcgagtc cgtagtaagg
     1081 catgaagttc attcagtgct gggtgatacg gtgctggaag atattcttcc gttgatgaca
     1141 aaaacgaact cgccaatctg ggtcgtaaat gagaatcggg agtttgaagg cgtagtgcca
     1201 ctttcctcat tgatcatcga agtaacggga aaagataaag aagaaattaa tgaaatcatt
     1261 caaaacgcaa tagaattatg ataaatatcg gacaatatat agagactgcc attaattggc
     1321 tcacagaaca ttttgcttcc ttttttgatg ctctcagcat ggggatcgga ggattcatag
     1381 acggttttca gcacgtactg tttggaatac ctttttatat cacaattgca gtgctggctg
     1441 cgctcgcctg gtttaagtcg ggtaagggga cagccgtatt taccctcttg ggtttattgc
     1501 ttatttacgg catgggcttt tgggaagaaa cgatgcagac attggcattg gtactttctt
     1561 ccacttgtct ggcattgctt ttaggcgttc cgttgggaat ctggactgcc aacagtgatc
     1621 gttgtaacaa gataatgcgc cctgtcctcg actttatgca gacaatgcct gcctttgtct
     1681 atctgattcc tgccgttcta ttcttcggat tgggaactgt gccgggagct tttgccacca
     1741 tcatctttgc aatgcctcct gtggttcgtc tgaccggtct gggcattcgt caggttccta
     1801 aaaacgtagt agaagcctcc cgctcttttg gagctactcc ctggcagctt ctttataagg
     1861 tgcaattgcc tttggcgttg cctactattc tgacgggaat caaccagacg atcatgatgt
     1921 cactttcgat ggtagtgatt gctgccatga tttctgccgg aggattggga gaaatcgtgc
     1981 tgaaaggtat cacccaaatg aaaatcggac tcggatttga aggcggtatc gcagtcgtga
     2041 tattggcgat cgtgctggac cgcatcactc agggtatggc agataacaga aaaagtaaaa
     2101 agaaataaga atcacaccaa agaaaggaat aatcaatgaa taagataaaa atgattgcgg
     2161 caatgtttat tgccggcata ctcttaacct tcgtttcctg cggagacaac ggaaagagta
     2221 agaagataag tatcgcttat gccaactggt cggaaggtat tgcaatgaca aaccttgcca
     2281 aagcgatttt tgaagatcag gggtacgatg taaagttgct gaatgccgac cttgcaccta
     2341 tatttacctc tatctcccgt aagaaagcag acgtatttat ggatgtctgg atgcctgtca
     2401 ctatggaaga ttatatgaaa caatacgggg ataaactcga agttatcggg gatatttatg
     2461 atggtgcccg tatcgggctg gtggttccgg attacgttac gatcaactca atcgaagaac
     2521 tgaacgcgga aaaggaacgt ttctccggtc agattgtcgg tattgatgcc ggagccggta
     2581 ttatgaaagc taccgatcag gccatcaaag actatggatt ggattataaa ctgatgactt
     2641 cgagcggacc tgccatgact gcttccctaa agaaagcgat tgataagaaa gactggattg
     2701 tcgtgacggg atggacgcct cactggatgt tcgaccgttt caagctgaaa gttcttcagg
     2761 acccgaagct gatatatgga aatacggaat ccattcatac catagcatgg aaaggtttta
     2821 gcgagaaaga cccttttgct gccgaacttt tgggcaacat tcgtctgaca gatgcggaaa
     2881 tcagctcctt aatgactgct ctggaagagg cgcagacaac ggaaagacag gctgcccgtc
     2941 aatggatgga agaacatcag gaactggtga acagttggat tcctgagaaa gattgatatg
     3001 caaacactac ttcaaccatc ccgccattct ttctttacca tagaagtagt agaaaagtag
     3061 tcccagccag ctggtaagaa cgattaatac aatcgctata agtcttttct ctacagccgc
     3121 atttatattc caaatctcta tggcagctct gaaagtcagt atcaaaccga taatccaaat
     3181 aacaaatccg atcatatctt tagagtttta atgaatatct tcgtgagaag taatcgttac
     3241 ttctaagata taaacaaaaa aggcaggaat ctgtttccag gattcctgcc ttttattatg
     3301 tacaaagtat ttctacttat tattcagctg tatcagctcc ccagttttct ctggcaagac
     3361 gtttgtagct gttgtaacgc catttagcgt tttcttcagc agctttaaac agttcttcag
     3421 cttcagcagg atattgtttc attacagaag cgtaacgaac ttcacccttc aagaaacctt
     3481 ggaagtcttc ccagttaggt tctttgctat ccagttggaa cggattcttg ccttcttctt
     3541 ccaaagcagg gttgtaacgc cacaagtgcc agtaaccgca cttaacagcc ttttcttctt
     3601 cttcctggct cttacccata ccggctttca gaccgtggtt gatacatgga gcgtaagcga
     3661 tgatcagtga tggtcccgga tatgcttcag cttcacggat agctttcaga gtctgagcct
     3721 ggtcagcacc catagcaatc tgagcaacat atacataacc gtaagtagta gccatcagac
     3781 cgaggtcttt cttacgtaca cgcttacctg cagcagcaaa cttagcgata gcgcctaccg
     3841 gagtagcttt agaagactga ccacctgtgt tagagtaaac ctcagtatcc aatacaagga
     3901 tgttaacgtc cttaccggaa gcgattacat ggtcaagacc accgtaaccg atatcataag
     3961 aagcaccgtc accaccgatg atccattggc tgcgtttaac aagatattgt tgcagatcag
     4021 cgatttgctt gcagtggttg catttatctt tagcagcttc taccatcgga atgatctttt
     4081 cggccagttc cttagtcttt tctgcatcca gcatattgtt gatccattca gcaaatactt
     4141 ctttgtattc agccgggcag caatcagaag cgatagcttc gttcattact ttcaccagac
     4201 gggcacgcat cttttcgtta gccagttcca tacccagacc aaattcacag aagtcttcga
     4261 acaaggagtt agcccatgca ggaccgtgac ccttttcgtt catagtgtac ggagtagaag
     4321 gaactgaacc ggagtagata gaagaacatc ctgtagcgtt agcaaccatt tcacggtcac
     4381 cgaacaactg agaaatcagt ttcacgtacg gagtttcacc acaaccggag caagcgcctg
     4441 agaactcaaa caacggagtt gcgaactgag agttcttcac gttagccttg atgtctacca
     4501 ggtgttgttt gctcttcacg ttttcagcgc agtaagtcca gttatcagct tcggccaact
     4561 ggctttcaag gtgtttcatg gtcaatgcct taccaccctt cttcggatta cccggacaga
     4621 tgtcggcaca gttaccgcaa cccagacagt cgagaacgtc tacctgaata cggaatgtca
     4681 taccatcgaa tgctttacct acagctttca gttgctcgaa cttagcaccc ttctgctctt
     4741 cagcatcgag tacgaacgga cggatagaag cgtgaggaca aacgtaagca cacttgttac
     4801 actgaataca gttttcagca ttccattcgg gaacgaatgc agctacacca cgtttttcgt
     4861 atttggaagt accttgatac caagtaccgt cttcgatacc cttgaatgca gataccggca
     4921 gcaagtcacc gtcctgtgca ttgatcggac gaactacttc gttgatgaaa gcaggatcat
     4981 tgttttctgc ttttgcatca tccggcaggt tagcccaagc aggatcgaca gtcagagtct
     5041 tgtattcacc accgcggtct acagcagcgt agttcttgtt aacaacgtct tcacccttct
     5101 tgccgtaaga cttaacgatg aatttcttca tctgttcaac agcttgatct acagggatta
     5161 cgcctgtgat acggaagaat gcagactgaa ggattgtatt ggtacggttg cccaaaccaa
     5221 tttccattgc aatctgagtt gcgttgatat agtatacaga gatgttgttc tgtgcaaagt
     5281 atttcttcac cttgttaggc aggttcttag ccagttcttc gccttcccag atggtgttca
     5341 gcaagaaaga accgttctta cgcaaaccac gtgttacgtc gtacatgtgc aggtaagcct
     5401 gaacgtgaca agcaacgaag ttcggagtat ttaccaagta agtagaacgg atcggagtat
     5461 caccgaaacg caagtgagaa caagtgaaac cacccgactt cttggagtcg taagagaagt
     5521 aagcctgaca gtgtttgtcg gtgttgtcac cgataatctt aacagagttc ttgttggcac
     5581 ctactgtacc gtcagcaccc agaccgtaga atttagcttc gaacatacct tcaccgccca
     5641 gagcgatttc ttctttctga ggaagagaag tgaacgtaac gtcgtctacg ataccgatag
     5701 tgaagtggtt cttcggcatt ggcatagcca agttttcgaa tacagagatg atctgtgccg
     5761 gagtggtatc ttttgaaccc agaccgtagc gaccgccaac gataacagga gcattttctg
     5821 cgccatagaa gcagtcttta acgtcaaggt aaagaggttc gccgttagca cccggttctt
     5881 ttgtacggtc aagcactgcg atgctctttg cagtcttggg tacagcagcc aggaagtgtt
     5941 tagcagagaa cggacgatac aagtgtacgg caaccatacc tactttttcg ccgtttgcta
     6001 ccaagtggtc gatagcttcg cgggcagctt cagttacaga acccattgcg ataattacgc
     6061 gttctgcatc ttctgcaccg tagtaatcga acaaaccgta tttgcggcct gtgatcttgg
     6121 aaatttcgtt catgtattct tctacgatag caggaactgc ttcatagtag ttattgcatg
     6181 attcacgatg ttggaagaag tggtcggggt tttcagccat accacgggca accggcttca
     6241 tcggattcag tgcacgggca cggaattcag ccaaagcttc ctggtcgatc agcggagcga
     6301 ggtcgtcgtt ttccaacatt tcgatcttct ggatttcgtg agaagtacgg aaaccatcga
     6361 agaagttcat gaacggaacg cgtgatttga tagtagccag atgagcaaca cctgccaaat
     6421 ccataacttc ctgtacagaa ccttctgcca acatagcgaa gccggtttga cgagctgaca
     6481 ttacgtcctg atggtcaccg aagatacaca atgcgtgaga agccagtgta cgagcagaaa
     6541 cgtggaatac acaaggcaag aattcaccgg caatcttgta catgttaggg atcatcaaaa
     6601 gaagaccctg agaagcagtg taagtagtag tcaatgcacc agcctgaaga gaaccgtgaa
     6661 ctgcaccggc agcaccacct tcagattgca tttcctgtac caatactgtt tcgccgaaga
     6721 tgttcttacg tcctgcggca gcccattcgt ctacgtactc agccatagtc gaagaaggag
     6781 tgatggggta gatagctgct acttcagaga acatatacga gatatgtgct gcagcttggt
     6841 taccatcaca tgtgatgaat ttcttctgtt tagtcataac taaattaaat atttaagtaa
     6901 ataaatcttt ttagtataag aatccgaaca tccagagagg tatttggttg ccgcggccta
     6961 tctcagcctt ttgcaacgca tacgtcacgt ccgggttatt ctttattttt gtaccttccg
     7021 cacaaatttt gaacggcatc acttcgtcta ccatgaaaga gacgttttta tctcctttat
     7081 gtaccttatg gtctttccat aaagtgttaa cgaagaacgt gtcgagtaca tcctgttctt
     7141 ccactttcac cggataaatg gagtacatca ggttagagtt gtgcatcata atctttgacg
     7201 gtttctttgg gaattcttct cctttcgggt aaaccagatt aatcagacgc gcgtctgcca
     7261 gatacttgat atagttcatt accgtagcgc gggatgtctg tacgtcactt gccagttggc
     7321 tcacgttcgg agctttcggt ccgtccacag ccaacaaata tagtaatttt tttatctttg
     7381 aaagatattt cagctcaatt tgtttgatca gcaggatatc cacttctacc atcatgttca
     7441 ttgttttcag cagattctcc gagaaatttc gtttttcaag gaagaaaggg tagaaaccat
     7501 gatgcaggta atcctgaaaa taatccagcg gtcgtacttt ggaaagtact cctttggcta
     7561 tctgttcatg tgtactgagg atttcttcga ggctgtatgc ccggaatttc attcctgtct
     7621 gcaagttcag aaattcacgg aaagagaatc cgcgcaggtt ataacttttc gcaatgtcac
     7681 gcaattcgag gttttcctct ttgagtcgca tgacggaaga accggtgaag acaatcttca
     7741 ggctggggaa acggtcatag cacattcgta gctctttgct ccattcggga tgtttgaaca
     7801 cctggtcgat cagcagtact tttccgccac gtttctgaaa ctcgttggcg aagtcaacaa
     7861 ggctgtgacc ggagaaataa aagttgttca tattgatgaa cagacaggaa cgatcggtgc
     7921 cgaatttctc tttggcgtac tgcaggagga aagtggtttt tcctacgcca cgtgtccctt
     7981 tgataccaat cagacggtca ctccagtcga tctcgtccat aagatcgcgg cgaacggggg
     8041 cattggtgtg ctcaacgagg taggcgtgtg tgcgatagaa tgattccatt tcgtttcttt
     8101 gtttttcggc tggcaaatat agtgcttttt ttaggatttg caaagtagag atagcaaaaa
     8161 tgtgctttaa tttataagtt tctctttatt gtgtaagttc ctgattattt cctgtatata
     8221 tttgcagaat aatgtgttga atccatcttt gacatgacga aaagacctgt ttatatattc
     8281 aatccggagc atgatatggc gttggcaagc ggtgagacga actatatggc gccggcttcc
     8341 gcccgacaga tggcgagtga cctggcgttg cttcctatgt ggtatgccga agcgggaagt
     8401 gcggtgcttg caccgtctgc ttataatgcg gacttcctga aaacaaagag tgaacttttg
     8461 ggcatggatg tggccttgtt gacggaaccg gaagtggctg acggtaaaga ctggaagttc
     8521 tctccgtggg gttgggaccc tgctttgcgg aagcgtttga tgacattggg ggcaggtcag
     8581 acggagctgc cttctgcgga ttatatgaat attctgagag agcattcgca tcgtctgcag
     8641 gcggtaaagt tgttgcctgg gttgcggttg aatgaatact tctgtggaga atctttttat
     8701 ttgagtactt tggcggagtg cagtgcgttc gtcgaagggc gggaagcgtg cttgttaaaa
     8761 gctccgcttt ccggaagcgg gaaaggattg aattggtgta aaggcatatt tactactttt
     8821 atttccggtt ggtgtgcccg tgtcgctgct tctcagggtg gggtggtagg cgaacctata
     8881 tataataagg tggaagattt cgctatggag ttttatgctg acgggagagg aagggttgtt
     8941 tttgccggat attcggtctt ccacacgggt gggagtggga tgtatgcagg gaatgacttg
     9001 ctgtctgacg agaagattct gcagaaacta tcggcttatg tgccacaaga agaatttatc
     9061 aggctgcgga ctcgtttgga agaagaattg tcagctttgt tcggtggctt ttatcatgga
     9121 tacttgggag tggatatgat gatttgtcat tttccggatg aagcgcctgt ttaccggatt
     9181 catccttgtg tcgaaattaa tctgcgaatg aatatggggg tggtggcatg gctcttgacg
     9241 gatcgttatt tggctgcgga tgcggaagga gtttttcgga ttgattatta tcctttagcc
     9301 ggtcaggctt tggaggaaca tcggcagatg tcggcttcgt tccctttgtc cgtagagaat
     9361 aatcgggtgt gtgccggata tttgccgtta gtaccggtga cgcctcaaag ccggtatcgt
     9421 gcgtttcttt tgcttactct cccccagtga aaaagatagt gcttttgctc tcatgctcta
     9481 acagttcgtc tgtatccctt tattcatcga tgttttagct gttagagatc cagtggtagc
     9541 agagtgagag caaggacttg ctctcactct gcatcgtcct gataaatacc gtttttactg
     9601 tgttattctt tgatttacag gatgttaata tctgatatct caactgttaa cgtttgattt
     9661 ctcagatatt aataattgag aaatcaagta ttaaggactg ataatttatg tattattgac
     9721 tgatatatga tttaatgttt tcagagagag cagtactatt gaagtagctg atgcgttcaa
     9781 tgtgattgga acatgcggtt aagtcaatca aatcaacagt agtttcagat agtttcgagc
     9841 gtttggaact aaagtttcaa gcgtatgaaa ctctagtttc tcaccgatga aactacagtt
     9901 tcacaccgat gaaactctgg tttcaagcaa tggaaactct ttgaagatac tgctaaattg
     9961 gaattggtga acatcggaaa agtcatattg tggtaatact gtctgaaatg cctacttatc
    10021 tccatttatg ggtgcactct cattcccgca acggtcgata gccgttactg caaaatactt
    10081 cttggcattc caaggctgga tgggtgcata aatgtaactt gtttcacgaa tactttgtgc
    10141 gacaatattt tccgctttct ttgtatctac cggatattca ttggaagcat aaatcacgta
    10201 catcggttta ttccgttggt cattatccgt cgctggttgc cagttcaatt cggtatatcc
    10261 gttgtcgatg gacgtaactt tgagtgctga gggggcagac ggcggaacgt tatccaacca
    10321 tgtcatcggg ggctgtaatg ccggataggc atagaagttc tcaatcagtt cgtcataaat
    10381 tccctgagta ttgtccatca gatacttgac acggtaatgc ccttctcctg ccattttctg
    10441 attacggatg aaattaatct gacgatccac ttcgtcgcgt gtccacttcc cttcgtcggg
    10501 atggaggaaa tagatgccca gccccggaat aacctgtcgt ccgttgctct gttcctgcca
    10561 gtcgagcgcg aaaggataga aactgtttcc ctgaaaatac atcatgggat atatctgatc
    10621 ctgaatacct tctccgagcc atccttgcgg gtcttgataa acggtataga acgcattcca
    10681 accacgggaa gaatagcggg aagtatctct gtattttcct acagggcaag tacttacctt
    10741 tacccacggc ttcattgctt tcacaccttt atatatgtac cggacgattt cggaaatgtt
    10801 atcccgtcgc cattgatcca aagtacgtcc tttgctgtaa cggcggaaat cgtatttgtc
    10861 ggggaataga ggagcattct ccggatagcg caggtagtcg aaatgcactc cgtctatatc
    10921 atagcgctcc accacttccc gaacgagtct catgagatac tctttcgtag caggatgccc
    10981 cggattaagg aaatattcat ttttataagg cacgcatata tctttcactc gcttggtgac
    11041 agattgtttg ccgagagaag cgacgtgctt tttgttgcct agcggaatag tcaccatcca
    11101 cgcatgacat tccatccccc gcttgtggca ttcctcaatc gcaaaggcca acggatcata
    11161 tcccggattt cctccgactt ttccggtcag gatagaattg aacggttcga tggaagaagg
    11221 atacagcaca tctccgcgtg tacgggtctg aaacaggaca gtattgaagt tggcagcttt
    11281 cagtttatca aggatatcca ccaattcttc cttttgcttg cggatgccct gaggagtcgt
    11341 agcccgtgta cggggccagt ccagaccata tacagccgta atccatgctg cacgaacttc
    11401 gtgcttgggt tgcgccttag ccggaaagat aagaaacaaa agtgaaagaa tgaaaatagt
    11461 tcggtgcata ttattccctt ttagatgcta aatctctgca aagctagcaa aaatgtctgt
    11521 aaattgatta ttcctttttt atttaatgct atttgacaga aaattactga ttctctttta
    11581 gtggtatcta cattcttagc cgtcttttaa taaggtacga aatataaaat attaatataa
    11641 caagataata aacaatgaaa aagctactat ctgtgtcgct ctgtcttttg tttgcggcga
    11701 gtctgactgc ccagacggga aagattagag ttgctactgt tggaaacagt atcaccggag
    11761 gaacgaatga ttatggttat tacgcgatgc ctttggctga aatgctcggt gatgattatg
    11821 aagttaccaa atttggtaaa ggctcttccg gggtatttat aaaattaaga gaagatgcga
    11881 ctactcccga aaatcctaat gaatatcaat tcgcttacat taattctgag caatgcgcag
    11941 cggcacttga gtataaacct aatattgtca ttattaagtt tggtgcaaat gatgccaaca
    12001 agaagaattt cgaaaaatat ggtaaggaga cttttaaagc agactataag aagttgatcg
    12061 ctaaattcca ggctctttcg actaaaccgg atatttatat ttgtacgcct ccgccgatgt
    12121 attatggcga tgggggattt ctaggttcat ttgatgacaa tgtagcaaag aattatattc
    12181 agcctgccgt aagagagatt gcggaggaac ttaatctggt ctgtgtagat ctgtataatc
    12241 ccttgaaggg acatccggaa tttatgccgg gtggcaacga ttgggtgcat cccgaccata
    12301 gagggcatta tattatagcg aaggaagtgt ataaggcgat aacgggtgaa ttcgttatga
    12361 accccggtgg aataacagtg gctgcttcgg atatttctct ttcgggttcg aaggcgaaga
    12421 tgaagaatgg tgctattgaa aaagcgaaga acggtacgag attgtcattc gatgtacatt
    12481 ttggctcatt gcctacgtat gagaaagtag aggttgacgt gcaattgaat aaaaagaaat
    12541 cgggatactt ggatttctat ctggatactg aaacaattcc ttttgcctcg gttgatgttt
    12601 cgggtgccga ctctaagaat ttcactacac aatctgctct tttcgaccgt cggataaaag
    12661 gcaaacataa agtgactgta caatggagag gacaggatgc caaactgaaa tcagtaacta
    12721 tcaaggaaaa atatatgcct tatgtaaccg ataatgtgtc tcaggtctat ttggtaaaca
    12781 aggcaaccgg tatggtattg gattgtaatc cggattcgaa agtgatttct gccgcaaaat
    12841 atgattcgga aaagaagtcc caattgtttt gtatcgagaa tttgacgtat catatcctcc
    12901 gtgtcagaaa tatagcgacc aaccttcatg taatgaataa tggagataaa gtgattgtgg
    12961 gtaaaccggg tgatgactgg cgagtacatg atcctaaata tgcattgttc ctgacaccta
    13021 cggatgatga aggctattat tcattggagc tgtctcctga agcaagaata ggtttgtctt
    13081 ctgcgaacag tacagaggtg gtaggcaata gaagcggcca aattgaagac ttggataaat
    13141 ggaaaatcgt gacagcagat gaaatgaaga agcagtaatt cagaccttgg tgtatatatc
    13201 ggattaccta tattagcatt gaaaagaaag gaggttgtat ctaaaccttt gccggaagaa
    13261 caagaaacaa aagtgaaaga atgaaaatag ttcggtgcat attctttatt ttttgtttta
    13321 aatccctgca aagttagcaa aagtgtcggt attgttgggc tgtttcgtga gattatgtta
    13381 catttgcgac agttaaaaaa acaacacgcc atgattacat ttaccctgtg cctgctggcg
    13441 ttgatagcag gctatttcac gtatggacgc ctgatggagc gcgtctttgg tccggacgac
    13501 cgtaaaacac cggctcttac caaagccgac ggagtagact atattccgtt gcctacctgg
    13561 aaaatattca tgattcaatt ccttaatatc gccggactgg gtccgatatt cggtgcgatt
    13621 atgggagcga agttcggtac ttcttcttat ttatggattg tattgggaag tatttttgca
    13681 ggcgctgttc atgattactt tgccggaatg ctttctttac gtcatggggg agagagtctt
    13741 cccgaaatca taggccgtta tctggggctg actaccaaac agatcatgcg tggatttact
    13801 gttcttctga tgattctcgt cggttccgtc ttcgtagccg gacctgccgg actattggcc
    13861 aagctgactc cggaaagtct ggacgccacc ttttggattg ttgttgtatt cctatattat
    13921 attctggcta ccctgcttcc ggttgataag atcatcggta aaatatatcc gttgtttgca
    13981 gtagccttgc tgtttatggc ggtcggtatc ctggtgatgc tttatgtcaa tcaccccgct
    14041 ttgcccgaac tatgggacgg cttgcagaat accaatccgg atgccagtga actgccgatc
    14101 ttcccgatta tgtttgtgag tatcgcctgc ggtgccatat ccggtttcca tgccacgcag
    14161 agtcctttaa tggcccgctg catgacttca gaacgtcatg gacgtccggt tttctatggt
    14221 gcaatgatta ccgaaggcat cgttgctttg atatgggcgg cagccgctac ttatttcttc
    14281 catgaaaatg gaatggaaga aagtaatgct tccgtgatag tagacgctat cactaaagac
    14341 tggctgggag ctatcggtgg agtgctcgcc attcttggag taattgcggc tcccattact
    14401 tcgggagata ccgctttccg ttccgcccgc ctgattgtgg cggactttct gggactggaa
    14461 caaaaaagta tgcgccgtcg tttatacatt tgtattccga tgttcgcagt agctatcggt
    14521 ctgcttcttt atagcttgcg tgacgcggac ggatttaaca tgatctggcg ttactttgcc
    14581 tgggccaacc agacattggc ggtgttcacc ctctgggcta tcacagtcta ccttgtggta
    14641 gccaaaaagc cttattggat tacgctgatc cccgccttat ttatgacgag tgtttgttct
    14701 acttatatat gtattgctcc cgaagggctg ggactttcgc atatagtttc ctactgcatc
    14761 ggtataggat gcgtagtggt agctattgcc tggttcttta tctggctggg aaaacaaaaa
    14821 actagaaaac tatcagaatg aagaaaataa aaaaatcgac aggagttgct atcgcattcc
    14881 ttatttatgt atcagtaacg gcagcctatt tgttacctcg caacacggaa gtcggccaga
    14941 cggagaagat tcttacggtg gtaggttctt acgtcatcgt actcctgctt tggctcgtgc
    15001 tccggaagaa ggaacaaatg cgtgaacgcc gtaaaaaaga cgaacaatct attcacttaa
    15061 aaaagtaaat ttatgaagaa attagcttta gctatttgtc tgctggtggt atcaatagct
    15121 gcccaagcac aatttgagaa aggaaaaatg attcttaatc cttctgtaac gggattggat
    15181 ttttcgtata gtaaaaacga taaggcgaag tttggtattg gtgcgcaagc cggtacattc
    15241 cttgccgacg gtatcgcatt gatggttaat gtcggtgctg attggtcaaa acccgtagac
    15301 gaatacacat tagggacagg aatgcgtttc tactttaatt ccaccggtgt gtatctgggc
    15361 ggaggtctcg actggaaccg cttccgttgg agcggaggac atcaccagac tgactggggg
    15421 ctaggcatcg aagccggata cgcttacttc ctttcccgca ccgtaaccat cgaacccgcc
    15481 gtatattaca aatggcgctt caacgatagc gacatgtcac gtttcggcgt taaggttgga
    15541 ttcggattct acttctaaca atggataatt gaaaatggat aatgagctgc gctgtttact
    15601 gcatagccat tatccatttt caattatcca ttatccatta agcaagcttt tctttcagaa
    15661 actgccccgt atagcttgct ccgcaagcgg ctacttcttc cggtgtacct accgctacga
    15721 tatttccgcc tttgtctccg ccttccggtc cgaggtcgat tacataatcg gcacatttga
    15781 taacatccat attatgttcg atgatgacaa tgctgtgtcc ccgtcggatg agtgcgtcga
    15841 aggcatccag cagtttgcgg atgtcgtgga agtgcagtcc ggtggttggt tcgtcaaaga
    15901 taaacagggt cgggtcggct ttctcctgac tcagatagaa tgccagtttt acacgttggt
    15961 tttcaccacc ggatagggta gaagaggatt ggcctaattt gatatatccc agtccgacat
    16021 cctgtagcgg aagcagtctt tttacaatct tcttctgacc gtgttcggtg aagaattcga
    16081 cggcttggtt tactgtcatt tccagtacat catagatgtt cttatcctgg aatttcacct
    16141 ccagtgtatc tgctttaaaa cgtttaccgt gacaggattc gcattccagc accaagtctg
    16201 ccataaactg catttctaca gtgatggttc cttcgccttt acattcctcg catcgtccgc
    16261 cttcgctgtt gaaactgaaa tgtccggctg tgtatcccat ttgttttgcc agaggctgtt
    16321 ccgcccatag cttccggatt tcgtcataag ccttgatgta agtcaccgga ttggaacggg
    16381 acgatttgcc aatcgggttt tgatcgacaa attcgatatt tctcaagtta cgcaggcttc
    16441 cactgataga agagaactct cccgggcggt cgctgcattc atccagttcg cgttttagtg
    16501 cccgatagaa gatatcccgc actaacgtac tcttaccgga accggaaaca cccgtgacta
    16561 ctgtcatcac attgagaggg aactttacat tcactccttt cagattgttt tcgcgggcac
    16621 ctgtcagttc gatataattg ttccacggcc gacgatgttc gggaacggga atctcctctt
    16681 ctcccaacag ataacgtacc gtatgactat tgctgccttt tttcaggtct ttcatatcgc
    16741 cctgataaac gacttctcct cccaggcggc cggcattcgg accgatatcg atgatgtaat
    16801 cggcggcacg gattatttct tcatcgtgct ctaccactac cactgtgttt ccgagttcct
    16861 gcaattgacg caatacg
//
