LOCUS       c00045_gnlPro..        14883 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCAOOAJM_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 17:00:56
            Original ID  :: gnl|Prokka|KCAOOAJM_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 14508
            Orig. end    :: 29391
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14883
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[24508:29391]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14883
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14883
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14883
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             667..1284
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_15"
                     /sec_met_domain="Hexapep (E-value: 6.8e-08, bitscore: 23.1,
                     seeds: 216, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKSKRELAFFIQADRIMNGFPEKRSILTYMKEFFHPQRDILRFL
                     KLMRKCDYYANGSKNTLLFLFYKIKYSRTSQRLGFSIDYTSFGYGLVIPHYGTIVVGGP
                     NKIGNFAVLHTCTCIAGGGKNIGDGLYLSTGSQIVGNVKIGDNVTVATHSLVLSDCVAN
                     TLVAGSPSIVKKEDCQPWYRRDGELYFERVETVKYLKLKYGI"
     CDS             1637..2773
                     /locus_tag="ctg45_16"
                     /transl_table=11
                     /translation="MEKINKRLWIITELFPPDETSTSYILGEVANAMVQKYNVSVICGP
                     EVYDKRKKQDVNNKFTLHESIEVYRTEGADLDKNTTKGKVLSFLLISKRMITLVKKYIR
                     KGDKVLMVTNPAPMVPLMARLKKKVGFELHILVHDVFPENTRPAGLKLPMYGIFKHIFD
                     KAYSKADQLIVLGRDMKCVLLEKVEKVLKGKEDCPKITIIENWADIDNIKPQPFPEGKV
                     ILEYAGNIGRVQGLDKVMDKLPENVELHFYGTGAMEEKLKERKRKNVFFHGAYFRSQQN
                     EVLAACDIALVTLQDGMFGLGVPSKTYNILASGRPVLFLGPKGSEIDLLVREKGIGYCE
                     WPEKWDKEVLAEMGKKARALAEAEYSESVILKKILRVI"
     CDS             2773..3669
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_17"
                     /sec_met_domain="Epimerase (E-value: 3.1e-23, bitscore:
                     73.3, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLLFTGGTGFLGKNVRPILDKMYEVTTCGITSDDTIKVNLAKE
                     IPELEQHYDVVLHACGKAHVVPKTEVEKQAFFDVNYTGTVHLCNALEKVGVPNALVFIS
                     TVAVYGCEFGELITEEHLLKGDTPYAKSKIQAEKYLTEWCKKYNVVLGILRPSLLAGKD
                     APGNLGAMVDGVKRGFYMNIAGGKAVKSVLMAEDIARIMPALIKKGGVYNVCDTFQPTF
                     GQISESVANQLGKRKPISIPIWMAKCMALVGDLLGEKAPINSYKLEKMTRSLTFSNEKA
                     RKELDWEPLDVLTNYKI"
     CDS             3801..4790
                     /locus_tag="ctg45_18"
                     /transl_table=11
                     /translation="MTTYIIIFVLLLVVELVYFCIADSCNIIDKPNERSSHSMIVLRGG
                     GIIFLVGAWMWSVFFGFQYPWFLVGLTLVAGVSFVDDIHSLPDSVRLVVQFAAAVMAFY
                     QLGILHWSMWWIILLALIVYVGATNVINFMDGINGITTGYSLAVLIPLALVNMNSTFVE
                     ESLIISTILASLVFCVFNFRPKGRAKCFAGDVGSIGIAFIMLFLLGNVIIKTTDITWLI
                     FLLVYGVDGCLTIAHRIMLHENLGEAHRKHAYQIMANELKIGHVKVTSLYMVMQLLISL
                     GFIYLCPNTVLAHWLYLVTTLVVLAITYIFFMKKYYHLHEEYLVSLKK"
     CDS             4796..5242
                     /locus_tag="ctg45_19"
                     /transl_table=11
                     /translation="MEFDKEFLGKLLEQAMENPRLRQNFDLRTSSADTSQRMLNALQPQ
                     TEVPIHRHEKTSETVICLVGKLEEIIYEEVNEYVHEATSCCDDVIRQKSFKEVSRQILS
                     PAEGKFGIQIPAGAWHTINVIESSVIFEAKDGAYNGYGNTTDKE"
     CDS             5297..6082
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_20"
                     /sec_met_domain="SLBB (E-value: 2.6e-09, bitscore: 27.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLGYYVLAAFLLTACQSYKKVPYLQDAEVVLYSTQDTQLYDAK
                     IMPKDLLIIVVSCTSPELAAPFNLTVATQNNAVLNYTTTQPVLQQYLVDNEGNINFPVL
                     GELHVGGLTKKATEQMIVEKLKPYIKETPIVTVRMVNYKISVIGEVARPGTFTISNEKV
                     NILEALAMAGDMTVYGLRDDVKLIRENANGKQEIIPLDLNKAETILSPYYYLQQNDIIY
                     VTPNKAKARNSDVGNSTSLWFSATSILVSIASLLFNILK"
     CDS             6094..8532
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_21"
                     /sec_met_domain="CbiA (E-value: 3.1e-10, bitscore: 31.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEANQNSKERQTVEEQIDFRALLFKYIIHWPWFVGAVLLCLVGA
                     WFYLHWATPIYNISATVLIKDEKKGGGAGVSSELEDMGLSGLMTSSKNIDNELEVLRSK
                     TLVKEVVNQLGLYITYKDEDEFPAKGLYKTSPVQVSLTPQEAEKLKTSLVVEMTLQPEG
                     SMDVNVTVGEKGYQKHFEKLPAIFPTDEGTLAFFQEVDSVTLQDGTKVPRMEKSVRHIT
                     ATINKPMRVARGYCNSLSIAPTSKTTSVAVISLKNSSLQRGQDFINQLLEMYNRNTNND
                     KNEIAQKTAEFIDERIGIISKELGSTEANLESFKRDAGITDLTSEAQIALAGNAEYEKK
                     SVENRTQISLVNDLRKYLRGNEYEVLPSNVGLQDAALIGAIERYNEMLIERKRLLRTST
                     ENNPTIVNLDTSIRAMKANVQATLEGTLQGLMITKESLDREASRYSRRISNAPGQERAY
                     VSIARQQEIKAGLYLMLLQKREENAIALAATANNAKIIDEAIADDIPVSPKRSMIYLIA
                     LVLGVGIPVGIIYLIELTKFKIEGRADVEKLTSVPVVGDIPLTDEKNDKNGSIAVFENK
                     NNLMSETFRNIRTNLQFMLNNDQKVILVTSTVSGEGKSFVSSNLAISLSLLGKKVVIVG
                     LDIRKPGLNKVFQLSNKERGITQYLSNPETDLMELVQPSDVNKNLFILPGGTVPPNPTE
                     LLARNGLDRAIETLKKNFDYVILDTAPIGMVTDTLLIGRVADLSVYVCRADYTHKAEYT
                     LINELSFEKKLPNLCTVINGVDLKKRKYGYYYGYGKYGKHYGYGKRYGYGYGYGQDTKR
                     "
     CDS             8689..9210
                     /locus_tag="ctg45_22"
                     /transl_table=11
                     /translation="MSVIYKVVTRPSDPRVPNSPKKYYPHLITLGQSVNLKYIAQKMQG
                     YSSLSIGDIKSVIQNFVEKMKEQLLEGKSVNIEGLGVFMLTACSKGADAAKDVNAKSVD
                     SVRIFFQANKELRITKTATRADEKLDLISLDEYLKKLNASVTPNDPDDGENGGGGNEGG
                     GDEEAPDPTV"
     CDS             9569..9994
                     /locus_tag="ctg45_23"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKVIDITDVTAASYQVGERVMVIGETSMGMMAVTLAFIIPFVLLIVSLFAWMALIGNEL
                     YAALLSLAVLIPYYFVLWLNKTRMKQHFSFTIKPINN"
     CDS             10001..10882
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.6; E-value:
                     4e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_24"
                     /sec_met_domain="Fer4_7 (E-value: 1.9e-12, bitscore: 38.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6.3e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.3e-08, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6.2e-09, bitscore: 26.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 2.2e-08, bitscore: 25.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 5.5e-11, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.2e-06, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAATEAEPMVAVV
                     RCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNTIIELNFPPRKPKAEEAP
                     KTVAAEAPKVTE"
     CDS             10907..12244
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_25"
                     /sec_met_domain="Fer4_10 (E-value: 2.8e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.7e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 5.9e-51, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 3.7e-30, bitscore: 94.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.8e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKPAIFIDVEGDE
                     WEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             12251..13243
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_26"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.3e-120,
                     bitscore: 393.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIVKFLMKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPL
                     ALMKQAVHGDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPV
                     SIIVTVFVFAGIMHMVDPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             13270..13953
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_27"
                     /sec_met_domain="FMN_bind (E-value: 2e-23, bitscore: 73.8,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     YTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILGMNPGETPLAV
                     TKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQKNEPAVAPEGEAAA
                     NDTNN"
     CDS             13989..14555
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_28"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.6e-70, bitscore:
                     226.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILPEEYGML
                     IFVLAPGAFIALGYLIAIINSLKKA"
     CDS             14578..14883
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_29"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.7e-35, bitscore:
                     113.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLGYLQTITFILVIAGLVQMVEIILKKVSPSLYQAL"
ORIGIN
        1 ttaatcatta tgctgctcag tttaattggg ctttagataa tgttggtata aagactactt
       61 gggtttacag aattgatgcc gatgaagttg ttactccgga actggccgct gaaattgttg
      121 atgcatgtaa tgaacatcgc aatgatgatg taaacggatt tgtaatgaag tttttgattg
      181 ctttcatggg aaaattcttg aagcatggcg gtatgtatcc attctataat cttacgatct
      241 ttaagtttgg aaaggggcgt tacgagaata gagctatggg cgaacatgta atcttgagcg
      301 aggggcgaag tcttgatttg aagaacgact gtctgcatta tgatttcaag agtcttgatg
      361 cttggatcaa caaacataat tggtatgcaa caagagaagt tgctgactac ttttcgacca
      421 gagctattgg acaagttgac ccgaattctt tgtaccatga ggcaaagaaa actagcaagc
      481 ttcgtgatgg tctttactat aggatgccta aatatctgcg tgcaaaatta tatttttggt
      541 accgctatta tattaagttg ggatttcttg acggaaaagc tggttatgtg catgcgttcc
      601 ttcaggcata ttggttccgc ttcttagtag atgcaaaaat aatggaacaa gaaattaaga
      661 gcagtcatga taaaaagtaa aagagaactg gctttcttca ttcaagcaga tagaataatg
      721 aacggttttc ctgaaaaacg aagtatcctt acttatatga aggaattctt tcatccacaa
      781 agggatattc ttcgtttctt gaaattgatg cgtaagtgtg attattatgc aaatggaagt
      841 aagaatacac tacttttctt attctataaa atcaaataca gtcgtacatc tcagaggttg
      901 gggttctcta tagactatac ttcttttggt tatggtttgg ttatcccgca ttatggaact
      961 attgttgttg gcggtccaaa taaaataggg aattttgctg tactccatac ttgcacatgt
     1021 atagctggag gaggaaaaaa tataggtgat ggactgtatc ttagtacagg atctcagatt
     1081 gttgggaatg taaaaattgg agataatgtt acggtggcaa ctcacagtct tgttctttca
     1141 gattgtgtgg cgaatacact cgtcgcgggc tctccttcaa tagtaaaaaa agaagattgc
     1201 caaccttggt atagaagaga tggcgaattg tattttgaaa gagtggaaac tgtaaaatat
     1261 ctaaagttaa agtatggcat atagatagga ctaggattct ttaaaaggca ttgcaattat
     1321 tgtactagtc ttgtttaata tgggactgtt gaagttagaa tactatggaa tggatgtatt
     1381 tcttgtattg ttctgttgct gtttaacagt atagttaagg cacgtttttt gttttttaaa
     1441 caattctttc aagtgatagt aatggtgagg atatttgact aataggtgtg gcgtgaaatt
     1501 ttgaataaat gttcatttta atgtttttat gtagaaagta ctgaaagtgc tttcttgtgc
     1561 ttacacagca gaactgaacg tttacaatct attataattt gctattaaaa tagtatgtaa
     1621 aatatgtaaa tgttgtatgg agaagattaa caaaagactg tggattataa cagaactgtt
     1681 tcctccagat gagacttcta caagctacat cctaggagag gtagctaacg cgatggtaca
     1741 gaagtataat gtgagtgtga tttgtggtcc ggaagtatac gataaacgta agaaacagga
     1801 cgtcaataat aaattcacac tacatgagag tatagaggtg tatcgtacag agggtgcaga
     1861 cttggacaag aatactacca agggtaaagt tctctctttt ttgctaataa gtaagaggat
     1921 gattactctc gtgaagaagt atattcgtaa aggtgataag gtcttgatgg tgaccaatcc
     1981 ggcgcctatg gtgccgttga tggcgagatt gaagaaaaag gtgggatttg aactccacat
     2041 acttgtgcac gatgtatttc cagagaatac ccgtccggct ggattgaaac tccctatgta
     2101 tggaatattc aaacatatct ttgacaaggc ttatagtaaa gctgaccaac tcatcgtatt
     2161 gggacgagac atgaaatgtg tcttgttgga gaaggtagag aaagttttga aaggtaaaga
     2221 agattgccct aaaattacga ttattgagaa ttgggcggat attgacaata ttaaaccaca
     2281 gcctttccct gaaggtaagg tcattcttga atatgcaggt aatatcggtc gtgtacaggg
     2341 gttagataag gtgatggaca aattgccaga aaatgtggaa ttacattttt atggtacagg
     2401 agcgatggag gaaaagctta aggaaagaaa gagaaaaaat gtcttctttc atggtgctta
     2461 tttccgctct caacagaatg aggtgttggc tgcttgtgat attgcccttg tgactcttca
     2521 agatggtatg ttcggactgg gggtaccaag taaaacctac aatattttgg cgtcaggtcg
     2581 tcctgtcctt tttcttggac cgaaaggtag tgagatagac ctgttggttc gtgagaaggg
     2641 cattggctat tgtgaatggc ctgagaaatg ggacaaagag gttttggcag aaatgggtaa
     2701 gaaggctcgt gcattggctg aagctgaata ttctgaaagt gtaatattaa aaaagatctt
     2761 gagggttata taatggagaa actacttttt accggtggta cgggcttttt aggaaagaat
     2821 gttcgtccga tattggataa gatgtatgag gtgacaactt gtggcatcac ttcagatgat
     2881 acgataaagg ttaatttagc aaaagagatt cctgagttgg aacagcatta tgatgtggtg
     2941 ttgcatgctt gtggtaaagc ccatgtagtg cccaagactg aagtagagaa gcaggcattt
     3001 tttgatgtta actatacagg tacagtccat ttatgcaatg cacttgagaa ggtgggagtg
     3061 cctaatgccc ttgttttcat cagtactgtg gctgtatatg gttgcgagtt tggtgaacta
     3121 attactgaag agcatctatt gaagggtgat actccgtacg ctaagagtaa gattcaggct
     3181 gagaaatatc tgactgaatg gtgtaaaaag tacaatgttg ttcttggaat tctccgtcct
     3241 tcacttctcg caggtaagga tgctccaggc aaccttggtg ctatggtaga tggtgtgaag
     3301 agaggctttt acatgaatat tgccggaggt aaagcagtga agagtgtttt gatggcagaa
     3361 gatattgctc gtatcatgcc tgctttgata aagaaaggtg gtgtgtataa tgtatgcgat
     3421 acattccaac caacttttgg tcagattagt gagtcggtag caaatcagct gggcaagagg
     3481 aagcccatta gtatcccaat atggatggct aagtgtatgg ctttagttgg cgatctctta
     3541 ggggaaaaag ctccaataaa cagctataaa ctggagaaga tgaccagaag tctcaccttt
     3601 agtaatgaga aagcacgtaa ggaacttgat tgggaaccgt tggatgtact aacaaactat
     3661 aaaatttgat tgaaaacact cttttgttgc attttattcg cagagtatta tatagaaatt
     3721 cttgatgaca ataatctttg aaatacattc atagttatag ataaaaccac actagataga
     3781 ttaaaatata actaagccat atgacaacat acattattat tttcgttttg cttctcgttg
     3841 tagaactcgt ttatttctgt attgcagata gctgtaacat tattgataag cctaatgagc
     3901 gttcatcaca ttctatgatt gtattgcgtg gtggaggtat aattttcttg gttggtgcat
     3961 ggatgtggag tgtattcttt ggttttcagt atccttggtt cttagtagga ctaacactgg
     4021 tggcaggcgt gagttttgtg gatgatattc attcattgcc agattctgtg agattagtag
     4081 tacagtttgc agctgcggta atggcttttt atcagttggg tatactgcat tggtcaatgt
     4141 ggtggataat attactggca ctaatagtat atgttggtgc gacgaatgta ataaacttta
     4201 tggatggaat caatggtatt acgacaggat attctttggc tgtgttaatt ccgttggcat
     4261 tggtaaatat gaatagtact tttgttgaag agagtttgat tatatctacg attctcgctt
     4321 cactggtgtt ctgtgtcttt aattttcgac cgaaaggtag ggctaaatgt tttgccgggg
     4381 atgttggctc tatcggcatt gcctttatca tgctgtttct attgggtaat gtgataatca
     4441 agactacgga tattacttgg ctgatatttt tattagtcta tggtgtggat ggttgtctaa
     4501 ctattgcaca tcgtattatg ttgcatgaga atttgggcga ggcacaccgt aagcacgcct
     4561 atcagattat ggctaatgaa ttaaagattg gacatgtaaa ggtgacatct ctgtatatgg
     4621 ttatgcagtt attgatttct cttggattta tttatctctg tcccaataca gtgcttgctc
     4681 actggctgta tttggttact acattggttg tattagctat tacttacatc ttttttatga
     4741 aaaaatacta ccatttacat gaggaatatc tcgtatcatt gaaaaaataa tagttatgga
     4801 atttgataaa gaatttttgg gaaaattatt ggaacaggct atggagaatc cacgtttgcg
     4861 tcagaacttc gacttgcgta cttcatctgc cgacaccagc caacgtatgc tcaatgcttt
     4921 gcaaccacaa acagaagtgc ctattcatcg acatgaaaaa acatcagaaa ctgtaatatg
     4981 tcttgtcggt aaattagaag aaataatcta tgaagaagtg aatgaatacg ttcatgaggc
     5041 aacttcctgt tgtgatgatg tgataagaca aaaaagcttt aaagaagttt cacgtcagat
     5101 actatctcct gcagaaggta aattcggtat ccaaatacct gcaggggcgt ggcatacgat
     5161 aaatgttata gagtcttctg ttatttttga agcaaaagac ggggcatata atggatatgg
     5221 aaatacaaca gataaagagt gattgagttt taatgacgat agaataaaaa acaatataaa
     5281 gaaatatatg aagagaatga aacaactagg ctattacgta ttggcagctt ttctgttaac
     5341 agcctgccag tcttacaaaa aagtacctta cctgcaggat gctgaagtgg tattgtatag
     5401 tactcaagat acacaattgt atgacgcaaa gattatgcca aaggatttgt taatcattgt
     5461 ggtttcgtgt actagtccag aattggcagc gcctttcaat ttgacagtag ctacgcagaa
     5521 taatgctgtt ttgaattata caactactca gcctgttttg caacaatatc tagtggataa
     5581 tgaaggtaat atcaactttc ctgtattggg cgaacttcat gtgggtggat tgacaaagaa
     5641 ggcgactgaa cagatgattg tggaaaagtt gaaaccttat attaaggaaa cacctattgt
     5701 aacggtacgt atggtgaatt ataagatttc cgtgattggt gaggttgccc gtcccggtac
     5761 atttacgatt tccaatgaaa aggtgaacat cctggaagct ttggctatgg caggtgatat
     5821 gaccgtatat ggtctgcgtg atgatgttaa gctgatacgg gagaatgcca atggcaagca
     5881 ggaaattatt ccgttggact tgaataaggc agagactatt ctttctccat actactattt
     5941 acaacagaat gatatcatct acgtgactcc caataaggca aaagctcgaa actcagacgt
     6001 gggaaatagt acaagtttat ggttctctgc tacttcgatc cttgtttcta ttgccagttt
     6061 gttgtttaat atcctgaaat aaaagaaaga attatgaaag aagcaaatca aaacagtaaa
     6121 gaacgtcaaa cggttgagga gcagattgat ttccgggcac tgctttttaa atatattatt
     6181 cactggccct ggtttgtagg tgctgtgttg ctatgtttgg ttggtgcgtg gttttatctg
     6241 cattgggcta cgccaattta taatatttcc gccaccgttc tgataaaaga cgagaagaag
     6301 ggtggaggtg caggagtttc ttcggaattg gaggatatgg ggttaagtgg cctgatgaca
     6361 tcttctaaaa acattgataa tgagttggaa gttctacgtt cgaaaacctt ggtaaaagag
     6421 gtggttaatc agttgggact gtatataact tataaagatg aggatgaatt tcctgctaaa
     6481 ggtttatata agacatctcc ggtacaagtg agtttgacac ctcaagaggc tgaaaaactg
     6541 aaaacttcgc tggtagtaga gatgacctta cagcctgaag gtagtatgga tgtgaatgtg
     6601 actgtaggtg aaaagggtta tcagaaacat tttgaaaagc tgcctgccat ttttccaaca
     6661 gatgaaggta cattggcttt ctttcaggaa gttgattcag taactttaca ggatggaacg
     6721 aaagttcctc ggatggagaa gagtgtacgt catataactg cgacaataaa taaaccgatg
     6781 agagtggcaa gaggttattg taacagtctg tctattgccc ctacttctaa gactacttcc
     6841 gtagccgtaa tttcattgaa gaactccagt ttgcagcgtg ggcaggattt catcaaccag
     6901 ttgcttgaaa tgtataatcg caatacgaac aatgataaga acgagattgc tcagaagacg
     6961 gcggaattta tcgatgaacg tattggcatt atctcaaaag aattgggtag tacagaagct
     7021 aatctggagt ccttcaagcg tgatgccggt atcacggatt tgacgagtga agctcagata
     7081 gccttggccg gtaatgcgga atatgaaaag aagagtgtgg agaatcgtac tcaaatcagc
     7141 ttggtgaatg acttgcgtaa gtatttgcga ggtaatgaat atgaagtttt gccaagtaat
     7201 gtgggtttac aagatgctgc cttgattgga gcgattgaac gttataacga gatgcttatt
     7261 gaacgtaaac gcctgctgcg tacgtcaaca gagaataatc ccacgattgt taacttggat
     7321 acgagtatcc gtgccatgaa agccaatgtg caggctactc ttgaaggaac cttgcaggga
     7381 ctgatgatta ccaaagagag ccttgaccgt gaagcgagtc gctattcccg ccgtatcagc
     7441 aacgctccgg gacaggaacg tgcttatgta agtattgccc gtcagcagga gatcaaggcc
     7501 ggattgtatc tgatgttgtt acagaaacgt gaagagaatg ctattgcgct tgctgctact
     7561 gcgaataatg cgaagatcat tgatgaagcg atagctgacg atattccggt atctcccaaa
     7621 cgctctatga tctatttgat tgcattggta cttggtgttg gaattccggt tggtatcatc
     7681 tatttgattg aactgactaa attcaagatc gaaggtcgtg ccgatgtaga gaaactgaca
     7741 agtgtgcctg ttgtcggtga tattccatta actgatgaga agaatgataa gaatggttct
     7801 atcgctgtct tcgagaacaa gaataatctg atgagtgaaa ccttccgtaa tattcggacc
     7861 aatcttcagt ttatgctcaa taatgatcag aaggtgatcc ttgtgacctc gactgtcagt
     7921 ggcgaaggaa aatcattcgt ctcgtcgaat ttggcaatca gtctttctct tttgggaaag
     7981 aaagtggtga ttgtcgggct cgatattcgt aagccaggac tgaataaagt attccagctc
     8041 tctaataagg agagaggtat tactcagtat ctttccaatc ctgaaacgga tttgatggaa
     8101 cttgttcagc cttctgatgt aaataagaat ctgtttattc ttccgggtgg tactgttcct
     8161 cctaatccaa cagaactgtt ggctcgtaac ggtttggaca gagcgataga aactttgaag
     8221 aagaacttcg attatgtcat ccttgatact gctcctatcg gcatggtgac ggatacctta
     8281 ttaataggtc gtgtagcaga cttgtcagtt tacgtatgcc gtgctgacta cactcataag
     8341 gcggaatata cattgatcaa tgaactgtct tttgagaaga agctgcctaa tctttgtact
     8401 gtcatcaacg gtgtagacct gaagaagcga aaatacggtt attactacgg ctacggtaag
     8461 tatggcaagc attacggcta tggcaaacgt tatggctacg gctatggata tggccaagat
     8521 acaaaaagat aaatatctga atatctatga attataactt ttctcagaaa aagagccccg
     8581 caaggggctt ttctttttgt tatctgaaat aaaagcctca cctttgcatt gttgatcaac
     8641 aaaacgtgaa taaaataact tgaatttgaa tctttaaaaa aacgtattat gagtgtaatt
     8701 tacaaagttg ttacgcgacc atctgacccg cgtgttccca attctcccaa gaaatattat
     8761 ccgcatctga tcactttagg tcagtctgtc aatctgaaat atattgcgca gaaaatgcag
     8821 ggctattctt ctttatccat cggtgatatc aagagtgtga ttcagaattt tgtggagaaa
     8881 atgaaagagc aacttctgga aggtaagtct gtgaatatcg aaggcttggg tgtatttatg
     8941 ctgactgcct gctcgaaagg ggcggatgcg gcgaaagacg tcaatgctaa aagtgtggat
     9001 agcgtgcgca tcttctttca ggcgaataag gaactgcgta tcacgaagac ggctacccgt
     9061 gcagatgaaa aactggattt gatcagtttg gatgaatatc tgaagaagtt gaatgcctct
     9121 gtgactccga atgatccgga tgatggtgaa aatggcggtg gtggaaatga aggaggagga
     9181 gatgaggaag ctccggatcc gactgtataa tctgaaaagc ttaaaaaaga aaggaggaaa
     9241 aatctatgaa gaaaacttgg agtgtagttt tgaaagtaat cattgctgta gccggtgcga
     9301 ttgccggagt actgggagta caggctgcat cattgtaagc agcattcagt aaataaagta
     9361 attggttaga taagacaggc aggcgggaag aactttcccg cctgctttgt tgtatgctaa
     9421 aatatcaaat agttggcgtt actttttcgt gtgcgataac gaaaacacaa aaaataacat
     9481 tttattatgt agaaaaaaat gagggaatgc ttcgtagttc acaaataatg attaaatttg
     9541 ccgcgatttg taatgttgag tttgcaaaat gacgaataat actataaagc atctaggtat
     9601 tgtggaaaac atacagggtt ctcatctgtc ggtgagaatc gttcagacgt cggcttgtgc
     9661 ggcttgtagc gcaaaaggcc actgttcttc ggcggatagt aaagacaaag tcatagatat
     9721 aacggatgtt acagctgctt cctatcaggt aggagagcgg gtgatggtga tcggcgaaac
     9781 gtcgatgggc atgatggctg taacccttgc attcataatt ccttttgtac ttctgattgt
     9841 ttccctgttc gcatggatgg cgttgatagg gaatgaactg tatgcggctc ttctttctct
     9901 ggcagttctt attccttatt atttcgtatt gtggctcaat aaaacgcgaa tgaaacaaca
     9961 tttttcattt actataaaac caataaataa ctaaaacatt atgaatttga ttctgattgc
    10021 agtgatttca ttgggagcta tagcgctcgt gctggccgct attctttatg tagcttccaa
    10081 gaaatttgcc gtgtatgaag acccgcggat tgcccaggtg ggggaagtgt tgccccaggc
    10141 aaactgtggt ggatgtggct atcctggttg tagcggattt gccgatgctt gcgtcaaagc
    10201 cggttcgctg gatggtaaat tctgccctgt aggcggtcag cctgtcatgg cacaaattgc
    10261 tgatattctc ggactggcag ctactgaagc tgaaccgatg gtagcagtag taagatgtaa
    10321 cggaagctgt gccaatcgtc cgcgtattaa tcaatacgac ggtgcgaaga gttgcgctat
    10381 tgccgcttca ttgtatggtg gagaaacagg ttgtagctac ggatgcctcg gatgtggcga
    10441 ctgtgtggct gcctgccagt ttgacgctat ccacatgaat cctgaaacgg gacttccgga
    10501 agtggatgaa gccaaatgta cagcttgtgg cgcttgtgtg aaggcttgtc cgaaggcgat
    10561 catcgagatt cgtccgcaag gcaagaaatc acgccgtgtg tacatctctt gtgtgaacaa
    10621 agacaaggga gccgtagcac gtaaggcttg tacagtgagc tgtatcggct gtggtaagtg
    10681 tgtcaagact tgtccgttcg aagccattac gctggagaac aacctggctt acatcgatcc
    10741 gaacaagtgt aaatcatgcc gtaagtgcgt ggaagtttgt ccgcagaaca cgattatcga
    10801 gctgaacttc cctccacgta aaccgaaggc ggaagaagca ccgaaaacag ttgctgcaga
    10861 agctccgaag gtaacagaat aataacagaa taaaatacag aattgtatgt taaagacatt
    10921 ttcaattggt ggagttcatc cacacgaaaa taaattgtcg gcacatcaac ctatcatcac
    10981 agcggaagtt cctgcaaagg cagttattct gttggggcag cacattggcg cacctgccaa
    11041 accgatagta gcaaaaggtg atatggtgaa ggtaggcacg aagattgccg aacctgccgg
    11101 cttcgtttcg gcagcaattc actcttctgt cagtggaaaa gtggcgaaga ttgatacagt
    11161 agtcgatgcg agcggttatg caaaacctgc tatctttatt gatgtagaag gcgacgaatg
    11221 ggaagaaacc attgaccgta gcaagacact ggtcaaagaa tgtgagcttt cgtccgaaga
    11281 aatcgtgaag aagattgccg atgccggtat cgtaggtttg ggtggtgctt gtttccctac
    11341 acaggtgaaa ctttgtccgc ctccttcgtt caaggcagaa tgtgtgatta tcaatgcggt
    11401 ggaatgtgaa ccgtatctga ctgccgacca tcagctgatg ctggaacacg cggaagaagt
    11461 catggtaggt gtctccattc tgatgaaagc cgtgaaggta aataaggcat ttatcggaat
    11521 tgagaataac aagccggatg ctattgaact gatgacgaaa gttgcttcca gttatgcagg
    11581 catcgaagtt gttcctttga aagtgaaata tcctcagggt ggtgagaaac agttgattga
    11641 tgcgattacc aaacgccagg tggcaagtgg tgcgctgcct atctctactg gggcagttgt
    11701 gcagaatgtg ggtacggcat ttgctgttta tgaagctgtt cagaaaaata aaccgttgtt
    11761 tgagcgtgtg attaccgtaa ctggcaagtc tgtggccaaa ccttccaact tcctggcgcg
    11821 tatcggtaca ccgatgaaac agctgattga tgcttgtggc ggtctgccgg aggatacggg
    11881 aaaagtgatc ggtggcggtc cgatgatggg taaggctctg gtgaatatcg aagttcctac
    11941 cgcaaaaggc agttccggta tcctgattat gaatcagaag gaagccaaac gtggtgaagc
    12001 acaaacctgt atccgttgcg caaagtgtgt gagcgcttgt ccgatgggac tggagccgta
    12061 cttgctcgga gctttgtccg aaaacggaga ttttgaaaca atggaaaaag aaagaatcat
    12121 ggattgtatc gagtgcggtt cctgtcagtt cacttgtcct gccaaccgtc cgctgcttga
    12181 ttactgccgc ttgggtaagg gtaaagtagg agctatgatt cgtgcacgtc aagctaaaaa
    12241 ataacgaagt atggaaaata aattaatcgt atcactatca ccccacgtgc atggcggaga
    12301 cagcgtacag aaaaatatgt atggcgtgct gatcgcactg attccggctt ttctggtgtc
    12361 gctttatttc ttcggcctgg gggctctgat tgtcacggct acttcggtag cagcctgttt
    12421 attcttcgaa tgggcgatcg ttaaattctt aatgaagaaa cctgctacaa ccatttgtga
    12481 cggttctgct gtcattacag gtgtgttgct ggcattcaat ctaccttcca atctgcctat
    12541 ctggattatc attctgggtg cactgttcgc aattggtgta ggcaagatgt ctttcggtgg
    12601 tctgggctgc aacccattca acccggcatt ggcgggacgt gtattcctgt tgctttcttt
    12661 cccggtgcag atgacaacat ggccggtagt aggtcagctg acatcttata tggacgctac
    12721 caccggtgct actccgctgg cattgatgaa acaggctgtt cacggcgatg caagtgcttt
    12781 gagccagata cctgatgcgc tgactctgtt tatcggacag aacggcggat gtatcggtga
    12841 agtaagtgcg ctggcactgt tgctcggact ggtatacatg ctctggaaaa agatcatcac
    12901 ctggcatatt ccggtttcta tcattgtgac tgtatttgta tttgcaggca ttatgcatat
    12961 ggtggatccc gaaaagtatg tttctccggt attgcaacta ctctccggag gtctgatgct
    13021 gggagctgtc tttatggcaa ccgactatgt gacttctccg atgagcaaga aaggtatgct
    13081 gatttacggt gtttgtatcg gtctgctgac ggtggttatc cgtctgttcg gtgcatatcc
    13141 cgaaggtatg tcattcgcca tcctgattat gaatgcgttc actccgctga ttaacaccta
    13201 ttgtaaacct aaacgctttg gggaggtagc gaagaagaaa tgaaaaagtt acaatcatct
    13261 ttaaagaata tgttgctggt acttacgggc gttacagctg tttccgtagc gttgctggct
    13321 tatgtgaacg aactgacgaa aggccctatt gccgaagcga atgcaaagac gctgaacgag
    13381 gccttgaaaa aggtgcttcc tgaatatacc aataatccgg tagccgaaag cgatactgtt
    13441 ttcagcgaga aagacggaaa gaaaatcgtg gatttcatta tctatccggc caagaatggc
    13501 gaaaagtggg taggttctgc cgttgaagcc aagtcaatgg gatttggcgg tgaactgaaa
    13561 gtgctggtgg gctttgatgc tgaaggcaag atttataact actctttatt ggcgcacgct
    13621 gaaactccgg gattgggttc gaaagcggac aaatggtttg gagcttatga tcctgcaaag
    13681 aacgaaaaac cggtatctca cgaagaaagt gcaaagtcta ttttgggcat gaatccggga
    13741 gagactccat tggctgtgac caaagacatg aatggacagg tagatgctat cacggcttct
    13801 actatcactt cacgtgcttt cctgaatgcg gtgaatgctg cttatcaggc atataaaggc
    13861 ggtgaggtgg atacgaattc cggagcttcc cagaaaaatg aaccggctgt tgcgccggaa
    13921 ggtgaagcag ctgctaatga cactaataac taagaaagga ggagacagtt atgaataatt
    13981 ttaaagtaat gatgaacggg attatcaaag agaatcctat ttttgtgctc ctgctcggta
    14041 tgtgtcctac actgggtacg acatcatcgg caatcaacgg tatgggtatg ggactggcca
    14101 ctatgttcgt cctgatttgc tcgaacgtgg taatttcatc tatcaagaat ctgattccgg
    14161 atatggtacg catcccttca tttatcgtgg tgatcgcgtc attcgtgaca ctgttgcaga
    14221 tgataatgca agcatacgtg cccgatctgt atgctaccct cggtcttttc attccgctga
    14281 tcgtagtaaa ttgtatcgta ttgggacgtg cggaagcttt tgcagcgaag aacaatccgc
    14341 tggcttctat gtttgatggt atcggtatgg gatttggttt taccattgcc ctgactctgt
    14401 tgggtgccgt acgtgaattc ctcggaacag gtaagatatt taatctgacc attctgccgg
    14461 aagaatacgg aatgctgatc tttgttttgg ctccgggtgc ctttatcgct ttaggttatc
    14521 tgattgccat tattaatagt ctgaagaaag cctaactcta ttaaataaga aaagaatatg
    14581 gaatatatat tgatatttat ctcggcaatc tttgtaaaca acattgtgtt gtcgcagttc
    14641 ctgggaatct gtccgttcct gggtgtttcc aagaaggtgg aaacagcgat gggtatgagt
    14701 gcggcagttg ctttcgtgct gactatcgct accatcgtca cattcctgat tcagaagttt
    14761 gtgttggacg ctttcggatt ggggtactta cagacaatca cttttattct ggttattgcc
    14821 ggactggtgc agatggtaga aattattctg aagaaagttt ctccttcttt gtatcaggca
    14881 ctg
//
