LOCUS       c00050_gnlPro..        14756 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKJLALBK_50.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 12:45:25
            Original ID  :: gnl|Prokka|FKJLALBK_50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 8516
            Orig. end    :: 23272
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14756
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[18516:22071](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13555
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..14756
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14756
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             660..3710
                     /locus_tag="ctg50_6"
                     /transl_table=11
                     /translation="MKIKYWAGFIVLLILACVNVQCDSSVRSTGDALEEGFKSPPKSAN
                     PGVYWYFMDGNLSKEGITKDLESMARVGISHAIFLEVNAGVPRGKVDMLSPEWMDIFKH
                     MVSESERLGVRLSIATGPGWAGTGGPWVKIEEAMQHLVASTVIVEGSDITNVVLPKPVA
                     RKRFYGDFVFTPDQRKDWEDFYEDVAVLAFPTPEGNEMIGDADEKSLYGRHPYSSMFGV
                     KQFLSTSASYPTAEGSVVNPVDIIDLTSRLRADGSVEGKLPAGKWTIMRFGVRNTGAVT
                     SPAPLPGLGFETDKMDTTAISHHLNNFVGEIFRYAGFQKRTPQSPYGGLAMLHFDSWEM
                     GSQNWTSKFREEFKQRRKYDPQPFYPAYTGFIVGSRELTERFLWDLRKTIQELILENHI
                     GYIREYAHEHGLELSIEPYDMTPVADLELAAAADVPMCEFWRAGFGFNTTFSLTEATSV
                     AHLKAQPVVPAESFTALSDGWDLYPGLLKNQTDWALAAGVNRLMFHTFVHQCFPDSVKP
                     GMTMGGIGVQWNRNQTWWEMSKAYHDYLSRSQFLLQQGRTVSDILYLCPEGNPHVFKAP
                     TSAYSKPDSAYDVLYIHANETFERRPASENQDINILPDKKGYAFDACPPSLLYKATVKN
                     GQIVFPGGAEYRLLVLPNWETMTPEMLKKIKELIMDGATIVGIPPEKSPGLQNYPQCDN
                     EVKTLVEDIWGKEGMPTTVGKRMVGKGQVIWGQDLIKNQDNSYPAYDCIAGLLSEMNIP
                     EDFISNGCLRYTHRTVNECDIYFVSNRSGKPVHTDCIFRVDNRIPELWDALTGEIRELK
                     SFSTDNGQTIVPMQFDTDQSFFVVFRKDGEPSSGKDNFPSFTTVQVLNKPWSVSFEPSM
                     GGPEKVVFEKLTDWSTNENDSIKYYSGIGIYCQTFDMKKTSDKQFYLDLGEVNVMAKVW
                     LNGEEVGTAWTYPWQLDISKYIKSGENQLKIEVVNPWVNRLVGDKVLSDKGVREQYTNT
                     TYQPYNTASPLLKSGLLGPVRILEVVK"
     CDS             3749..4921
                     /locus_tag="ctg50_7"
                     /transl_table=11
                     /translation="MKNRLCLLFVFLCYSIFAFGEGKKQQYDVAAYIWPAYHDDPRFKE
                     INIFPEGKGEWEAIYKAKPKFEGHRQPRVPLWGYLDEADPKVQEKKIDIALEYGVNTFI
                     FDWYWYDDKPFLERVLNEGFLKARNNEKMKFYLMWANHTQTGYLDPNEPDKSKVFWKGE
                     VDFDIFDRFTDHVIKDYFMKPNYYRIDGMPVFAIYELSTFINGLGGMEEAKKALDHFRK
                     KCVKAGLKGVHLQAILWHALPATLSGVPGDKSDTQDNTVKYLGFNSLTNYQWVHFVSIN
                     QDYASWGEKAISKYKEFSESFSIPYFPHVSIDWDNNPRFPGGPQPAVSNVTPQKFEKFL
                     YKAKEFIDKHPDQTPLVTINAWNEWGEGSYLEPDTEFKYGFLEAVKKVFK"
     CDS             complement(5004..5108)
                     /locus_tag="ctg50_8"
                     /transl_table=11
                     /translation="MKYILFITMDLAVYPFLLLIYIVKCIFDKIQPVH"
     CDS             5418..6326
                     /locus_tag="ctg50_9"
                     /transl_table=11
                     /translation="MMNRRLFLKKACGGVLVLAASPSFVSCGGQRPVRFGVVTDLHYSR
                     REPYGTRYFPQTMDKLKEAMEVFNSSNLDFVIEMGDLKDQDNVSQREQTITYLDEIENV
                     FQSFRGPVYHVLGNHDMDSISKDDFLQHTSNQGDADKKAYYSFAFDNIKFIVLDANYNL
                     DGTPYDKGNFDWTKAYIPKDQIDWLKKELKGNNKPVIIFIHQLLDRFSDISKSLCVSNA
                     DEIVPLLEENGNVLAVFQGHHHAGHYSFRNNIHYWTMKGMIEGNLPDNNSFAVVEIDTQ
                     NNIHIDGFYNCEDKDLNRFTV"
     CDS             complement(6549..7298)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_10"
                     /sec_met_domain="MTHFR (E-value: 2.4e-56, bitscore: 181.2,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDL
                     NFLGVYDLLLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGSTFEANETPF
                     SYGMACYPEKHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVKRCRAEGID
                     VPIIPGIKPVVFKNQLTVLPKIFRSDIPEPFATELRKCKNDDEVKAVGVEWCIQQCKDL
                     IAHGVPSLHFYTMMATDSVYKVAKEVY"
     CDS             7583..8602
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_11"
                     /sec_met_domain="Aminotran_4 (E-value: 1.7e-32, bitscore:
                     103.2, seeds: 70, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENMNWSDLAFGYMKTDYNVRCYYRDGKWGELEVSSSEIINIHMA
                     ATCLHYGQESFEGLKAFKGKDGKIRVFRMDENGKRMQASSRGIKMAELPVEMFEEAVRK
                     VVKLNERFVPPYESGAALYIRPLMIGLGAQVGVKPAPEYMFMVFVTPVGPYFKGGFKPS
                     KVCIMREYDRAAPYGTGTIKVGGNYAASLVAGEIAHEKGYAAVLYLDPKEKKYLDECGP
                     ANFFGIRGNSYITPQSHSILPSITNKSLQQLAEDMGLTVERRPVPFEEIATFDEAAECG
                     TAAVIAPISQIDDLDENKSYVIAKDGKPGPVCEKLYNKLRGIQYGDEPDTYGWVTVIE"
     CDS             complement(8757..8954)
                     /locus_tag="ctg50_12"
                     /transl_table=11
                     /translation="MFAGIIQQKSSFPYSTRAFDPDQPVIPINLIHQPPAYRCMQMFYK
                     VFMCFKECFHLTVLLYRPQR"
     CDS             9335..9775
                     /locus_tag="ctg50_13"
                     /transl_table=11
                     /translation="LFGSQTDGLFSGLFASWFLSVLPGETQFLREPVEDNEYDAGGRCL
                     VHQANRAKLSAQTPQTVVSAGYQRTVYAECQSVEQRNRNVTGYSDELYKISDRCPFNEY
                     VISGRRIVSEKTIYCVYVQFESDVPHPSDGGKCAGCARIFFL"
     CDS             9753..9968
                     /locus_tag="ctg50_14"
                     /transl_table=11
                     /translation="VRESFFYNQLLKDNTLNEGMKNAHFLVNGKYNFRIEENMKVKNNP
                     DLYYAVDKVEVGEENMIPLWLFGFLY"
     CDS             10001..13555
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_15"
                     /sec_met_domain="PFOR_II (E-value: 1.1e-19, bitscore: 60.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.3e-83, bitscore: 268.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 4.9e-32, bitscore: 101.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.2e-13, bitscore:
                     39.0, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 4.6e-13, bitscore: 40.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.7e-07, bitscore: 21.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6e-05, bitscore: 13.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 8.1e-25, bitscore: 76.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFLTCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVMVQEMQSEGGAAGAVHGSLQAGALTSTYTASQGLLLMIPNMYKIAG
                     ELLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFVNFFDGFRTSHEIQKIEALENDDLAPLIDQKALAEFRARALNPEKPEARGMAE
                     NPDHFFQHRESSNKYYEAVPAIVEEYMNEISKLTGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLTAQGEKVGLVSVHLYRPFSAKHFLAAVPKTAKRIAVLDRTKEPGATGE
                     PLYLDVKDCFYGQADAPVIVGGRYGLGSKDTTPAQILAVYENLALPMPKNQFTLGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKYCQAYFSYDS
                     KKSGGFTCSHLRFGDHPIRSTYLVNTPNFVACHVQAYLRMYDVTRGLRENGTFLLNTVW
                     NGEELANHLPNKVKRYFAQKNITVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DLAIEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYTQLAVDPSWANLPDDEVVANNDP
                     AFINEVVRPINAQDGDLLKVSAFKGIEDGTWRQGTAKYEKRGVAAFVPVWDGENCIQCN
                     KCAYVCPHASIRPFVLDAAEQAAAPFSNSLKATGKQFEGMQFRIQVDVLDCLGCGNCAD
                     VCPGNPKKGGKALKMVALEGQLAEAPNWEYCTEKVSSKQHLVDIKANVKNSQFATPLFE
                     FSGACSGCGETPYVKLITQLFGDREMVANATGCSSIYSGSVPSTPYTTNAKGQGPAWAN
                     SLFEDFCEFGLGMELANEKMRARLQAAMEASIANEACPAANKELYTEWIANQNDADKTK
                     ELAEKIIPMVEANKDKCPNCATIAELSHFLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KNVNILVLDTEVYSNTGGQSSKATPVGAIAKFAASGKRIRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYDGPSLIIAYAPCINHGLKKGMGKSQQEEADAVACGYWHLW
                     RYNPALEEEGKNPFSLDSKEPDWSKFQDFLKGEVRFASLTKQFPAEAAQLFQAAEDNAK
                     WRLNNYKRLAKQQWGVEE"
     CDS             13665..14321
                     /locus_tag="ctg50_16"
                     /transl_table=11
                     /translation="MAKNKSKQNQFQLLSPEKYIRLKARNLPIEVCYVSDDWKDERGAV
                     AEVIVVRRHAGGNYTFGVYVVDTLCLGVKHSVYRFNVPPDEYDDFVERTVTDCGIKISY
                     NEAHNFIYGAIAFAEEFGIKPDKSFALTQYILEEDTEEIPLIEYKYGRGGRPHLVAETS
                     LEASKYIPILEESTGGDFGLEILEDRDVFDDDEFDDEFDDDEFDDEYDEEDNKTM"
     CDS             complement(14588..14755)
                     /locus_tag="ctg50_17"
                     /transl_table=11
                     /translation="AVVCELAALKQHSLRTLSADASLNAHQLRPFIERFAFSWDGRYRL
                     LKKKGSVIII"
ORIGIN
        1 agaaatattt caaacatcct caatattata agatagatgg aaaacctgtt tttatgattt
       61 acgatatacc acagctgata gcaggtttgg gaggaatcga agaaacagca gatgctttgg
      121 attggttcaa gaaggaaacg aagaaggccg gattcccagg acttgagttg cagataacga
      181 tgtggtccat taatatgaac tatagtgggt tcgatgccgg gaaaacaacg aatcccgaga
      241 attcgtttgt gaagaaatta ggatttacta gcggaactca ttatcagttt gcccatttta
      301 cgaatgtaaa tgaagattat aatgtaatta tggacgctgt tgaaaaagaa tgggaacgca
      361 ttgattcttc ttacgacttt acttactatc ctcatataag tgtgggatgg gataatagtc
      421 cccgtacggg tgtaagtgca gttgtgaaga ataatacacc cgaaaatttt gaaaaagcac
      481 ttcgtcgtgc taaagctttt gccgaccggc atccgaagca gaaaccgctg ataaccataa
      541 atagttggaa tgaatggacg gagactagtt atctgatgcc ttgtaatgta tttggctatg
      601 gttatttaga ggcagttaaa aatgtatttg ttgattctaa ttaataaatg aattatcgaa
      661 tgaaaattaa atattgggca ggatttattg ttctgcttat tcttgcgtgc gttaatgtac
      721 aatgtgattc tagtgtaaga tccaccggag atgcattaga agaaggattt aaatcacctc
      781 ccaaaagtgc aaatccggga gtttattggt attttatgga tgggaacctt tcgaaagaag
      841 ggataacgaa agatttggaa tcaatggccc gggtggggat ttcgcatgca atttttctag
      901 aagtgaatgc cggagttcct cgtggaaaag tagatatgct cagtccggaa tggatggaca
      961 tatttaaaca tatggtttca gagagtgaaa ggttaggggt acgtttatct attgctactg
     1021 ggccgggatg ggcaggaact ggtggaccat gggtgaaaat agaagaagct atgcagcatt
     1081 tggttgccag tacagttata gtagaaggat ctgatataac aaatgtggtt cttcccaagc
     1141 ctgttgcaag aaaacgtttt tatggtgatt ttgtgtttac accggaccaa aggaaagatt
     1201 gggaggattt ttatgaagat gtagcagttt tggcatttcc tacaccggaa ggaaatgaaa
     1261 tgattggtga tgcagatgaa aagtctcttt atggcagaca tccttatagt tccatgtttg
     1321 gagtaaaaca atttttatct acatccgcat cttacccgac agcggaaggt tcagttgtaa
     1381 atcctgtaga cattatagat cttacctcca gactgagagc agatggttct gttgaaggaa
     1441 aacttccggc agggaaatgg actataatga gatttggagt gcgtaatacc ggtgctgtta
     1501 caagtccagc tccgttaccg ggattaggtt ttgaaacgga taaaatggat acgacagcaa
     1561 tctctcatca tttgaataat tttgtaggag aaatcttccg ttatgcaggt ttccaaaaaa
     1621 gaacaccgca gtctccttat ggaggtttgg ctatgcttca ttttgatagt tgggagatgg
     1681 gatcgcagaa ctggacatct aagtttcgtg aagaattcaa acaacgaaga aaatatgatc
     1741 cgcaaccttt ttatccggct tatacaggct ttattgtagg aagtcgtgaa ttaactgaaa
     1801 gattcttgtg ggatttgcgt aaaacaatac aagaactgat attggaaaac catatcggat
     1861 atattagaga atatgctcat gaacatgggt tggaactttc gatagaacct tatgatatga
     1921 ctccggtagc tgatctggaa cttgctgctg ctgcggatgt tcctatgtgt gagttctgga
     1981 gagccggatt tggatttaat acgactttta gtttgacaga ggcgacttcc gttgcacatc
     2041 ttaaagctca gcccgtagtt ccggccgaga gctttactgc ccttagtgat ggttgggatt
     2101 tatatcccgg tttgttgaag aaccaaacag attgggcttt agcggcgggt gttaaccggc
     2161 tgatgttcca tacatttgtg catcaatgtt ttcctgatag tgtaaagccg ggtatgacaa
     2221 tgggaggtat tggagttcaa tggaatcgta atcaaacctg gtgggagatg agtaaggctt
     2281 atcatgacta tctttcccgt tctcaatttt tattacaaca ggggcgtacc gtttcagata
     2341 ttctttatct ctgtccggaa ggaaatcccc atgtttttaa agcaccgacc tccgcttata
     2401 gtaaaccgga ttctgcgtat gatgtgcttt atattcatgc gaatgagact tttgaaagaa
     2461 gaccggcatc agaaaatcag gatataaata tcctcccgga taagaaggga tatgcttttg
     2521 atgcatgtcc acccagtctt ttgtataaag ctacagtgaa aaatggtcag attgtatttc
     2581 ctggtggagc tgagtatcgt ctgctggtat tacccaattg ggagacaatg acgccggaga
     2641 tgctcaaaaa aataaaagag ttgataatgg atggagctac aattgtaggc atccccccgg
     2701 aaaagtctcc tggtttacaa aattatcctc agtgcgataa tgaggtgaaa acattagtag
     2761 aagatatttg ggggaaagag ggaatgccca caacagtagg aaaacgaatg gttggaaaag
     2821 gacaggttat ctgggggcaa gatcttataa agaatcagga taattcttat ccggcttatg
     2881 actgtatagc tggtttactt tcagaaatga atattccgga agattttatc tctaacggat
     2941 gtttacgata tacacatcgt acagtgaacg aatgtgatat ctatttcgtt tccaatcgtt
     3001 ccggaaagcc ggttcatacg gactgtattt ttcgtgtaga taatagaatt ccggagttat
     3061 gggatgcttt aacaggtgaa atcagggaac ttaaatcttt ctcaacagac aatggacaaa
     3121 cgatcgttcc aatgcagttt gatacggatc agagcttttt tgtagtattc cgtaaagacg
     3181 gtgaaccctc ttctgggaaa gataatttcc catcatttac tacagttcaa gttctcaata
     3241 agccatggtc tgtttcattt gaaccgagta tgggtggtcc ggaaaaggtt gtgtttgaaa
     3301 aattgacaga ctggagtaca aatgaaaatg atagtattaa gtattattcc ggtattggta
     3361 tatattgtca aacatttgat atgaaaaaga cttctgataa acaattttat cttgatttgg
     3421 gagaagtcaa tgtcatggct aaagtttggc ttaatgggga agaggtcgga acagcctgga
     3481 catatccgtg gcaacttgat attagtaagt atattaagtc aggagaaaat caattaaaaa
     3541 tagaagttgt taatccctgg gttaatagac tggtaggtga taaggtgttg tctgataaag
     3601 gtgtacggga acagtatacc aatactactt atcaacctta taacacagca tcaccattat
     3661 taaaatcagg tttgctggga cctgtgagaa ttttagaagt cgtaaaatag attttataag
     3721 taaatgtatt attaaaaaag tagagaatat gaaaaatcga ttgtgtttat tatttgtgtt
     3781 tttatgttac tcaatttttg catttggaga agggaaaaag caacagtatg acgtcgcagc
     3841 ttatatttgg ccagcttacc atgatgatcc tcgttttaaa gagattaata tttttccgga
     3901 aggaaagggt gaatgggagg ccatttataa agctaaaccg aagtttgaag gacatcggca
     3961 acccagagtt cctttatggg gatatttgga cgaggcagat ccgaaggttc aggagaaaaa
     4021 gattgatata gctttggaat atggtgttaa tacgtttatc tttgactggt attggtatga
     4081 tgataaacct tttttggaaa gagttttgaa cgaaggtttc ctgaaagccc ggaataatga
     4141 aaaaatgaag ttttatttga tgtgggctaa tcatacgcaa accggttatt tagatccgaa
     4201 tgaaccggat aaaagtaaag tgttctggaa aggagaagtg gattttgata ttttcgatcg
     4261 ctttaccgac catgttatca aagactattt tatgaaacct aattattata gaatagatgg
     4321 aatgcctgtg tttgccattt atgaattgag tacattcatt aatggtttgg gtggtatgga
     4381 agaggctaag aaagccttag atcattttag aaaaaaatgt gtgaaagctg gcttgaaagg
     4441 tgttcatttg caggcaattt tgtggcatgc tcttccagcg acattatcag gagttccggg
     4501 agataagtcg gacactcagg ataatacagt caaatattta ggctttaata gtttgacaaa
     4561 ttaccaatgg gttcattttg tttcgattaa tcaggattat gcttcatggg gagaaaaagc
     4621 tatttccaaa tataaagaat tcagtgaaag tttctctatc ccttattttc cgcatgtttc
     4681 tatcgattgg gataataatc ctcgtttccc tggtggtcca caacctgctg tatcaaatgt
     4741 tacacctcaa aaatttgaga aattcctata taaagcaaaa gagtttatag ataaacatcc
     4801 ggatcagact cctttagtaa cgattaatgc ctggaacgaa tggggagaag gtagttatct
     4861 ggaaccggat acagaattta aatatggatt tctggaagca gttaaaaagg tttttaaata
     4921 agacttcccg atcctaatca tataattcag ctcaaaagga tattgaaatg tccctttggg
     4981 ctgatttttg tttgtattga aaatcagtga actggttgta tcttatcaaa gatgcatttt
     5041 actatataaa ttagtagcag aaaaggatat actgccagat ccatagtaat gaatagtatg
     5101 tatttcattt cttttttctt ttaaattcca cctgtaagac agaaatatat caaaaacccc
     5161 tatcggcctg acagattttt tgtatttgta tgaaaagaag atgagcaaag gctctaaaaa
     5221 gatgcatctg ggtttgaaat tggggtaatt taacaaataa gcttttttcg ggagattgaa
     5281 aatttgttct caactcatcc taaatccggg atggtagata tattgacttt ttattattaa
     5341 tattgtaagc caatgctgat agcctgctac atccggcagg ttaccggcat gactctataa
     5401 cctatgaaat ttttaatatg atgaacagac gcttattttt aaaaaaggca tgcggagggg
     5461 tgttggtcct ggcagcttct ccttcatttg tatcctgtgg tggacaacgg cctgtccggt
     5521 ttggggttgt taccgatctg cattattcgc ggcgggaacc ttatgggacc cgttatttcc
     5581 ctcagacaat ggataagttg aaagaggcca tggaggtctt caactcttcc aatctggatt
     5641 ttgtgatcga aatgggcgat ctgaaggatc aggataacgt ctctcagcgg gaacagacaa
     5701 ttacttatct ggatgaaata gaaaacgtct ttcaatcgtt ccggggaccg gtttatcatg
     5761 tcctgggaaa tcatgatatg gatagcatct ccaaagacga tttcctgcaa catacctcca
     5821 atcaggggga tgccgacaag aaagcttatt attcatttgc ctttgataat ataaaattca
     5881 tagtcctgga tgcgaattac aatttggacg gtacaccgta tgataaaggt aattttgact
     5941 ggacaaaggc atatattcct aaagaccaga tagactggtt gaaaaaagaa ttgaaaggaa
     6001 ataacaaacc ggtcatcatt tttatccatc agttgttaga ccgcttctcc gatatcagta
     6061 aatcgctttg tgtaagtaat gcggacgaaa tagttcctct gttggaagaa aatgggaatg
     6121 tgctagctgt attccaggga catcatcatg cgggacatta cagtttccgt aataatatcc
     6181 actactggac aatgaaaggg atgatagaag gaaaccttcc cgataacaac agttttgctg
     6241 ttgtggagat cgatacgcag aataatattc atatcgatgg tttctataat tgtgaagata
     6301 aggatttgaa tcgcttcacg gtgtaaagtt attcagttga tctgcgtaaa gcaatctaat
     6361 gttttttcag acagaggtag gtctaaataa atttagaggt aggtgtaaat cgaattagag
     6421 gtacgtctaa attcatttac acctacctct aatttataag acatagtaat gttctccgga
     6481 tttagtcagt attatgcttt ttatccaacc cgttgtctcc tggcaatcga ttagttccac
     6541 caacggtttt aatatacttc tttcgccact ttataaacac tatccgtagc catcatcgta
     6601 taaaaatgca ggctggggac accgtgggcg atcaggtctt tgcattgctg gatgcaccat
     6661 tcgacaccta cggcttttac ttcatcatca tttttacatt tccgcaattc ggtagcaaac
     6721 ggttcgggaa tgtctgaacg gaatatttta ggtaatacgg tcagctggtt tttaaagaca
     6781 actggcttga tgcctgggat gatcgggaca tcgatacctt cggcacggca gcgtttcaca
     6841 aatgaataat atttttcatt atcgaaaaac atctgggtaa ccagatagtc ggcaccgttt
     6901 tttactttct ctttcagata aaaaatatcc gattccatat tcggtgcttc ctcatgtttt
     6961 tccggatagc aagccatacc gtatgagaag ggtgtttcgt ttgcttcgaa tgtggaaccg
     7021 tctacggcaa tacctttatt gaaattgttt acctgttcct gaaggtcagt cgcatgttcg
     7081 tgatataaat ccgtattttg tccggcttcc agtgttttta catcaccacg caacagcagc
     7141 aggtcgtaaa ctcccaggaa attaagatcg atcaatgcat attccgtttc atcttttgta
     7201 aatcccttac atataatatg tggaactgcc ggaataccat atttgttctg gatggcagaa
     7261 gcaatggcaa ccgaacccgg acgcttgcgg atgttcactt tttggaagct gccgtcgggc
     7321 aaggtcttat agatatattc gctgtggtga gaagttatat taatgtattt agggtcgaat
     7381 tctttcagtt tatcaatcac attatatacc ttctgtatgc tgttcccttt cagaggaggt
     7441 agaatttcaa atgaaaaagc agtcgtttta ctgccgttga tcagatcaat aactttcata
     7501 ttttaattat ttttgctgca aaagtaacaa ttatcatccg aaatagctta cttttgcgct
     7561 cataatctaa ttacgacaag atatggaaaa tatgaattgg tctgatctgg cattcggtta
     7621 tatgaagaca gactacaatg tacggtgtta ctatcgtgat ggtaagtggg gtgaattgga
     7681 agttagctct tctgaaatta ttaatattca catggcagct acttgcctcc attacggaca
     7741 ggagtcgttt gaaggtttga aagcattcaa gggaaaagac ggtaaaatcc gtgtgttccg
     7801 tatggatgaa aacggcaaac gtatgcaagc ttccagccgt ggtatcaaga tggctgaact
     7861 tcctgtggaa atgtttgaag aagcagtccg taaagttgtg aagttgaacg agcgttttgt
     7921 tcctccctat gagagtggag cagcattata tatccgcccg ctgatgatcg gtttgggtgc
     7981 gcaggtgggc gtaaaaccgg ctcccgaata tatgtttatg gtattcgtaa ccccggtagg
     8041 accttatttc aaaggtggtt tcaaaccgtc aaaggtttgt atcatgcgtg aatacgaccg
     8101 tgctgcgcct tatgggactg ggacgatcaa agtcggtggt aattatgcag ccagcctggt
     8161 agccggagaa atagcgcatg aaaaggggta tgccgccgta ttgtatctgg acccgaaaga
     8221 aaagaaatat ctggacgaat gcggtcctgc caacttcttc ggtattcgtg gaaacagtta
     8281 catcactccg cagtctcatt ctattctgcc gtctatcact aacaagagtt tgcagcagct
     8341 ggctgaagat atgggactga cggttgaacg tcgtcctgtt ccttttgaag aaatagctac
     8401 attcgatgaa gcagcagaat gcggaacagc tgccgttatc gccccgattt cacagattga
     8461 tgatttggat gaaaataaat catacgtgat agccaaggac ggtaaacccg gacctgtttg
     8521 cgaaaaacta tataacaaac tgcgtggcat ccaatacggt gacgaacctg atacatacgg
     8581 ttgggttacg gtaattgaat aatcagataa aagatgttga cagttaatgt ttttagataa
     8641 accggaagca ttaactgcca actctaaatt ctcaaacgtc aatacgcttt gccaactttg
     8701 gattgccaac tgaaaataaa attgctatct cggtattgca aagttgagga tattttctat
     8761 ctttgcggtc tatatagtaa gacagtcagg tggaagcatt ctttaaaaca cataaatacc
     8821 ttgtagaaca tttgcatgca ccggtacgcc gggggctgat ggatgagatt gattggaatg
     8881 accggttgat cgggatcaaa ggctctcgtg gagtagggaa aactactttt ttgctggatt
     8941 atgcccgcga acattttggt gctgataata aagagtgcct gtatataaat ctgaatcact
     9001 tttattttac ggaacgtacg ctggtcgact ttgcttctga gttcagggca aaaggaggga
     9061 aggtgttgtt gattgaccag gttttcaaat attccggatg gtcgaaagag ttacgttatt
     9121 gttatgataa ttttgaagat ctgaagatta tcttttccgg ttcgtcagtg atgaggttga
     9181 aagaggaaaa tccggatctc tcaggtaaag ttgtttcata taatttgcgt ggtttttctt
     9241 tccgagagtt tttgaatctg atgtcgggaa acagttttcc ggcttatacg tttgaagaaa
     9301 taatcgggaa ccatcaggag attgcgaaga atatttgttc ggtagccaaa ccgatggctt
     9361 attttcagga ttatttgcat catggttttt atccgttctt cctggagaaa cgcaatttct
     9421 cagagaacct gttgaagaca atgaatatga tgctggaggt agatgtcttg tacatcaagc
     9481 aaatcgagca aagttatctg cccaaactcc gcaaactgtt gtatctgctg gctatcagcg
     9541 caccgtgtac gccgaatgtc agtcagttga gcaaagaaat agaaacgtca cgggctacag
     9601 tgatgaatta tataaaatat ctgaccgatg cccgtttaat gaatatgtta tatccggtag
     9661 gcgaatcgtt tccgaaaaaa ccatctactg tgtatatgta caattcgaat ctgatgtacc
     9721 ccatccgtcc gatggaggta aatgtgcagg ctgtgcgcga atcttttttc tataaccagc
     9781 ttttgaaaga caatacgcta aatgagggaa tgaagaacgc acactttttg gtaaacggaa
     9841 agtataattt caggatagag gaaaatatga aagtaaaaaa caatcccgat ttatactatg
     9901 ctgtagacaa ggtcgaagta ggagaagaga atatgatccc gctttggctg tttggctttt
     9961 tatactaaga aattctttta aatactaata gtaaaagtct atgacaaaac agaagaaatt
    10021 tttgacctgt gatggtaacc aggctgctgc tcatatttca tatatgttca gtgaagtagc
    10081 cgctatctac cccatcactc cgtcgtctac aatggcagaa tatgtagacg aatgggctgc
    10141 cgccggacgt aagaacattt tcggcgaaac tgttatggta caggaaatgc aatcagaagg
    10201 tggtgctgca ggtgcagttc acggttcttt gcaggctggt gccctgactt caacttacac
    10261 ggcttctcag ggattgttgc tgatgatccc taatatgtac aagattgccg gtgagttgct
    10321 tccttgcgta ttccatgtat ctgcccgtac actggcatct catgccttgt gtatcttcgg
    10381 cgatcatcag gatgttatgt ctgctcgtca gactggtttc gcaatgttgg cagaaggttc
    10441 tgttcaggaa gttatggact tggcgggtgt agctcatctg gcaactatca agtctcgcgt
    10501 tcctttcgtg aacttcttcg acggtttccg tacatctcac gaaatccaga agatcgaagc
    10561 tctggaaaat gatgacctgg ctccgctgat cgaccagaag gcgttggctg aattccgtgc
    10621 acgtgctttg aatccggaaa aaccggaagc tcgcggtatg gctgaaaacc cggatcactt
    10681 cttccagcac agagaatctt caaacaaata ctatgaagca gttcctgcta tcgtagaaga
    10741 atatatgaac gaaatctcca aactcacagg ccgtaaatat ggtttgttcg attactacgg
    10801 agcagaagat gcagaacgcg tgattatcgc aatgggttct gtaaccgaag ctgcccgcga
    10861 agctatcgac cacctgactg ctcagggtga aaaagttggt ttggtttctg ttcatttgta
    10921 tcgtccgttc tctgctaagc acttcctggc agctgttcct aagactgcaa aacgtatcgc
    10981 agttcttgac agaacaaaag aaccgggtgc aactggcgaa cctttgtatc tggatgtaaa
    11041 agactgtttc tacggacagg ctgacgctcc ggttatcgtg ggtggccgtt atggtttggg
    11101 ttctaaagat actactccgg cacagattct tgccgtttac gaaaatctgg cattgccgat
    11161 gccgaagaat cagttcacac tgggtatcgt agacgatgtt acattcactt ctcttcctca
    11221 gaaagaagaa atcgctttgg gcggcgaagg tatgttcgaa gctaagttct acggattagg
    11281 tgctgacggt acggtgggtg ctaacaagaa ctctgtaaag attattggtg acaatacaga
    11341 caaatattgc caagcatact tctcttacga ctctaagaag tccggtggtt tcacttgttc
    11401 tcacctgcgt ttcggtgatc atccgattcg ttctacttat ttggtaaata ctccgaactt
    11461 cgttgcttgt cacgttcagg cttatctgcg tatgtacgat gttactcgcg gtttgcgtga
    11521 aaacggtaca ttcctgttga acactgtatg gaatggcgaa gagttggcta accacctgcc
    11581 gaacaaggta aaacgttatt tcgctcagaa aaatattact gtttactata tcaatgcgac
    11641 tcagattgct ttggaaattg gtttgggtaa ccgtactaac acaattcttc agtccgcatt
    11701 cttccgcatc acaggtgtaa ttcctgttga tctggctatc gaacagatga agaaattcat
    11761 cgtgaagtct tatggtaaga aaggtgaaga tgtagttaac aagaactatg ctgctgttga
    11821 tcgtggtggc gaatatactc agcttgctgt cgatccgtca tgggcaaacc tgccggacga
    11881 tgaagttgta gcaaataacg atcctgcttt catcaacgaa gtggttcgtc ctatcaatgc
    11941 tcaggatggt gacttgctga aggtttctgc attcaagggt atcgaagatg gtacttggcg
    12001 tcagggaaca gctaaatacg aaaaacgtgg tgtggctgct ttcgttcctg tatgggatgg
    12061 tgaaaactgt atccagtgta ataagtgtgc atatgtttgt cctcacgctt ctatccgtcc
    12121 gttcgtgttg gatgctgctg aacaggctgc tgctccgttc tctaactctt tgaaggctac
    12181 tggtaaacag tttgaaggta tgcagttccg tattcaggta gacgttcttg actgtctggg
    12241 ttgtggtaac tgtgccgacg tttgtccggg taatccgaag aagggtggca aagcgcttaa
    12301 gatggttgct ttggaaggtc agttggctga agctcctaac tgggaatatt gcactgaaaa
    12361 ggtttcaagc aaacaacact tggttgacat caaggctaac gtgaagaact ctcagttcgc
    12421 aactccgttg tttgagttct ccggtgcttg ctccggttgt ggtgaaactc cgtatgtgaa
    12481 gctgatcact cagttgttcg gtgaccgtga aatggtagct aacgcaacag gttgttcgtc
    12541 tatctattca ggttctgttc cttctactcc gtatacaaca aatgcaaaag gacagggtcc
    12601 ggcttgggct aactcattgt tcgaagactt ctgcgaattc ggtctgggta tggaattggc
    12661 taacgaaaag atgcgtgccc gtttgcaggc agcaatggaa gcttctatcg caaacgaagc
    12721 atgtccggct gcaaataaag agttgtacac agaatggatt gctaatcaga atgatgctga
    12781 taagacgaaa gagttggcag aaaagatcat tccgatggtg gaagcaaaca aggataaatg
    12841 tccgaactgt gcaacaatcg ctgaactgag ccacttcctg gtaaaacgtt cacaatggat
    12901 catcggtggt gacggtgctt cttacgatat cggttacggt ggtcttgacc atgtaattgc
    12961 ttcaggtaag aacgttaaca tcctggtatt ggatactgaa gtttattcaa atacgggagg
    13021 ccagtcttct aaagctactc cggtaggtgc aatcgctaag tttgctgctt ccggtaagag
    13081 aatccgcaag aaagacctgg gtctgatggc tacaacttac ggttatgttt atgttgctca
    13141 gatcgcaatg ggtgccgatc aggctcagac gttgaaagcg atccgcgaag ctgaagctta
    13201 tgatggtcct tcattgatca ttgcttatgc tccttgtatc aaccacggtt tgaagaaggg
    13261 tatgggtaag agccagcagg aagaagctga tgcagtagca tgtggttact ggcatttgtg
    13321 gcgttacaac ccggctttgg aagaagaagg caagaatccg ttctctttgg atagcaaaga
    13381 accggattgg agcaagttcc aggacttcct gaagggtgaa gtacgtttcg catctctgac
    13441 aaaacaattc ccggccgaag ccgctcaatt gttccaggct gccgaagaca acgctaagtg
    13501 gagacttaac aactacaagc gtttggctaa acagcagtgg ggtgttgaag aataattgat
    13561 tatttgatca tctaaatagt aaaacggaat cttcgaaaga gggttccgtt tttttgtata
    13621 agccaaataa atcgtacctt tagcgaaact aaacaaataa gcaaatggca aaaaataaaa
    13681 gcaagcagaa tcagtttcag ttactctctc ctgaaaagta tattcgtttg aaagctagaa
    13741 atttaccgat agaggtgtgt tatgtttccg atgactggaa agatgaaaga ggggctgtag
    13801 cggaagtgat cgtagttcgt cgtcatgccg gtggaaatta tacattcgga gtttacgtcg
    13861 tagatacgtt gtgtctggga gtgaaacatt ctgtatatag gtttaatgtg ccaccggatg
    13921 agtatgacga ttttgttgaa agaacggtaa ctgattgcgg tattaaaatc agttataatg
    13981 aagctcataa ttttatttat ggggctatag cgtttgccga agagttcggg atcaaaccgg
    14041 ataagagttt tgccctgacg caatatatac tggaagagga tacggaagag attcctttga
    14101 ttgaatataa atatgggaga ggtggccgcc ctcacctggt tgccgaaaca tctcttgagg
    14161 caagtaagta tatccctata ctggaagaat ctacaggcgg cgatttcggt cttgagatat
    14221 tggaagatcg tgatgtgttt gatgatgatg aattcgacga cgaattcgat gatgacgaat
    14281 ttgatgatga atatgacgag gaggataata agacaatgta agaatattac aataataata
    14341 tagagggaat tggttcagtt tttatcagat ttgaatgtta cttttctctt gatagaaaag
    14401 taaccaaaag atcaaggctc aaccggcttc actgctccgg tgaaagactc cactcgaaaa
    14461 tccgaaactc gctccgctca aacaacggat tttcttaacc gttccgtctt tcatctccgc
    14521 ggacgttcac ccgcttaggc ctttcctagg aagctatgct tcctcttagg atggccgata
    14581 ccgacaccta tataataata acagatcctt tctttttcaa cagtcggtat cggccatccc
    14641 aggagaacgc aaagcgttct atgaaaggcc tcagttgatg agcgttaagc gaagcatccg
    14701 cagagagcgt ccggaggctg tgctgtttga gcgcagcgag ttcacagacg acagcg
//
