LOCUS       gnlProkkaHEONPLEH_5    13650 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HEONPLEH_5.
ACCESSION   gnlProkkaHEONPLEH_5
VERSION     gnlProkkaHEONPLEH_5
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 06:43:24
            Original ID  :: gnl|Prokka|HEONPLEH_5
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13650
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13650
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3299:3650]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3300..3650
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13650
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13650
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             309..1820
                     /locus_tag="ctg5_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1893..2960
                     /locus_tag="ctg5_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2997..3281
                     /locus_tag="ctg5_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3300..3650)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_4"
                     /sec_met_domain="PqqD_RRE (E-value: 1.5e-10, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.6e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(3748..5136)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg5_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5384..5779)
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVVKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5786..6559)
                     /locus_tag="ctg5_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6565..7092)
                     /locus_tag="ctg5_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7079..8320)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 383.7; E-value:
                     2.2e-116)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg5_9"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYLWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQVGTVVTTPVVTTHQPSVPA
                     IIHTMQPAVCKDDDDIQDTEEYVEEPPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8330..9424)
                     /locus_tag="ctg5_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9429..10469)
                     /locus_tag="ctg5_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQNQIPLGEASKE
                     AEQTNK"
     CDS             complement(10488..11522)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_12"
                     /sec_met_domain="PF04055 (E-value: 3.6e-17, bitscore: 56.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVLSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 gggcaggaat taaactactg agagcgaaga ttatttattc acaatagaag aagtaccacc
       61 aaatttgacg aagaaccaga aatctttttc aggaagaaat aaaagtaagt tcataatggt
      121 gcagcattga attatttttt ggcggagtta ttctaacact taatagttca aaagcagata
      181 tttctttgac caaaagatag aactaatgat gaattaaaag ttgcaattat ggttttcttc
      241 ccacaacaaa cgggaaaagt cagaagaatc atgtacattt gtaatccgaa aactaaaaga
      301 acatcgcaat gaaaatattt ccaagcagca gtatcaagaa attggacgct tataccattg
      361 agaacgaacc tattgcatca atcgatctga tggaacgtgc agcaaccgta ttaacaaaag
      421 ccatcacaga cagatggaat acggaaacgc cggtcactat ctttgccgga ccggggaata
      481 atggcggaga cgctctcgcc gtagcccgca tgatggctga aaaaggatat aaaatcgagg
      541 tatttctctt caacacgaaa ggagaacttt cacccgactg ccagaccaat aaagaactgg
      601 tagaaatgat ggaagaagta aaattccacg aaatcagtac ccaattcgta cctcccgtcc
      661 tgacgcccga tcatctggta atcgacggat tattcggttc aggcctgaac aaaccgttga
      721 gcggtggatt cgctgccgta gtgaaataca tcaattcctc ccctgccatg gtagtagcca
      781 tcgacattcc ttccggacta atgggagaag aaaatacatt caacgtaaaa gctaatatta
      841 tccgcgccga cgtaactttc agtctgcaac tgccgaagct cgcctttctt ttcgcagaga
      901 acactgaatt tgtcggagaa tgggaagtgc tggatatcca attaagcgaa gacggtattg
      961 aagagatgga gactaactac gaaatgttgg aaatagaaga aatccgttca ctcatcaagc
     1021 cacgcaaaca gtttgcccac aaggggaact tcggccatgc actattgatt gccggttcaa
     1081 aaggaatggc aggagcctct gttctcgctg cccgcgcctg cctccgttcg ggagtagggt
     1141 tgctgactgt tcatgcacca atgtgcaaca acgacatctt gcagacctcc atacccgaag
     1201 caatcgtaga aaccgacatc aacgaaacct gttttgccgt acctaccgat acggacgact
     1261 accaagcagt cggcatcggc ccgggactgg gacgaaacga ggaaacggaa gctgccttgt
     1321 tggagcaact ggaacactgc cagactcctg ttgtagtgga tgccgacgct cttaatatcc
     1381 tcgccaacca ccgccatacc cttacccacc tgccgaaggg ttccatcctc accccgcatc
     1441 cgaaagaact ggaacgtctg accggcaaat gccaggactc ttacgaacgt ctgatgaagg
     1501 cttgcgaact ggcccgtgcc gcccatgtcc acattatttt aaaaggagcc tactccgcca
     1561 ttatcacccc agaaggtaaa tgtttcttca acccaaccgg aaatccggga atggcaaccg
     1621 gaggtagcgg tgacgtactg accggagtaa tcctggcgct gcttgcccaa ggttatccca
     1681 ccgaagaagc cgctaaaatc ggcacttaca ttcacggatt ggcgggcgat gtcgctcaaa
     1741 agaagcaagg aatgatcgga atgatcgcaa gcgatattat cacctgtctg ccgacagcat
     1801 ggcgacttgt aagcgaataa aagttaagaa cttacagttt tttcaataac ttcattaact
     1861 ttgttttcaa aaccagttaa aaagaaccga atatgaaaaa gttgattata gcagcaggac
     1921 tacttatgac aacgtccgcc tatgcacaaa ccgaagtact gacaggggtt acccgaggaa
     1981 aagactatgg agtggtttac agtcttccca aaacccaaat agaacttgaa ataaaagcca
     2041 acaaagtcaa ctatactccg ggagaattca gcaaatatgc tgatcgttac ctgcgactga
     2101 ccaacgtctc cgccgaccct gaagagtact gggaactgac tagcgtaaaa gtgaaatccg
     2161 taggtgtgcc caacagcgaa acgacgtatt tcgtaaaatt gaaggataag acagtagcac
     2221 cgctcatgga actgacagag gatggcattg tgaaaacgat caatgttcct tacagcaaca
     2281 gcagtgtagg caaaaaagcc gctcccgctc ccacagtcct ccaaaagaaa gcaaatcctc
     2341 gtgaattcct gaccgaagag attctgatgg ctagctctac cgccaagatg gccgaactgg
     2401 tggctaaaga aatctataac atccgcgaaa gcaaaaatgc cttattgcgc ggacaggctg
     2461 acaatatgcc ttcagacgga gcacagctta agattatgct cgacaatctg aatgcacagg
     2521 aagaagccat gacgcaaatg ttctccggca cctgcaacaa ggaagagaga acattcactg
     2581 tccgccttac ccctgacaag gaatttaaca atgaagttgc tttccgcttc tcgaagaagt
     2641 taggtgtagt tgccaacaat gatttggcag gaactccgtt ttatatcagt ctgaaagacc
     2701 tgaaatcggt caagatacca caggaagatg gtaagaagaa gaaagatttg gatggaatcg
     2761 cctacaacgt acccggacaa gctatggtta cattgaccga cggcaaaaag aaactttacg
     2821 aaggtgaact tcctattact caatttggtg tgatagaata tctggctccg gttttgttca
     2881 acaagaattc taccatcaaa gtttattttg atccgaatac gggaggattg ctcaaagtgg
     2941 acagagaaga agggaaatag aaaaacgaga aagtgaactt ctaaaaaaca aagaatatgg
     3001 ttggtgaagg acatgcattc gacatgatac gccgaataaa agagggacgg gaagcttccc
     3061 gcctacgtcg tgaacgtgct aacgacaagt tgaagcattt aaaccgtgca aacgaacctt
     3121 atccactacc caataccact cccgaagaaa tggaacgtat catccacgac tcggagaaaa
     3181 agaaagagaa agacagcaat tattttgttt ggggaacgct tattatcatg ggagtcctga
     3241 tagcaattgc cgtcatactt tgggctgtat ttatcaaata aataataata aattcctatt
     3301 tatacgactg gtatcaccag ttttataaat ccatctttct gcatttgaga aagataagcc
     3361 gatacacgcg actcgtagcc ctcttcattt tgaaagtggt ctgcgagttt ttctataatc
     3421 tcacgaacat tgcgttttcc atctatcagt tcccatacag ccgtaccgtg ttcttccaat
     3481 ttcacatgaa gttctttcga cattcctttc ggcacaagga agcgttgcat ccacggatat
     3541 ttaaaacggg gaaaggagag cacaattgtc tccccttccc tttctgctgt aatatgttca
     3601 ctgcgacagg gaatgacctc taacaggttg attttctctt tggcagccat acttcttatt
     3661 ttttatttca gagtattcat actgataccc ttttgtttac accttgatac aaaattcctt
     3721 tgttacttta ggtattgaat ttcccagtta cttttggata ttcgcctctt ccagaccgta
     3781 tcccttcttc ttgttctctg ccttcaacat caaagccaca atcagagcaa gtacaccaaa
     3841 gagagcaaaa atagtcatcg gcaacgtgta gtcataagtc tgtgcaccgt ctactaccgg
     3901 acctttgcaa taagtattca acacccatcc gatcaacaaa ggaacaccca tcaatcccca
     3961 gttctgtacc cagaaaatca atgcgtatgc ggtacccaac tgtttttccg gaataatctt
     4021 cggaacagac ggccacatag ctgaaggcac caacgagaag gcaaatccca atataatcat
     4081 gatgatagta gcaaaccacc atatattcag tataggcaga gcaaacatcg tatgcacaaa
     4141 aataagcatc actgatccga ttatcatcaa tgtggctccc ttaccgatac ggtcataaag
     4201 cgaaccgaac aacggagtca ggataatcgc accaatcggc aacaatccgg gaatcgttcc
     4261 cgccaacttc ggatctacgt tatatttctg caccatcaag tcggcagcat acttgataaa
     4321 ggggaataca gccgagtaga acaatacaca tagtaatgca atcaaccaga atcctttatt
     4381 ggtaataata tacacaatat ctttcatacg gaacggttct tccggttcca atccctctgc
     4441 atccaaagaa gcatccaact tcttatcata gaaagtataa aggaaaaaag caatcgtacc
     4501 cacgcacaac ataatcagac aaaacaaaat cggagcagga atatttgtat ggaatgtgcc
     4561 actctcatcc gtagatccga aaaagtctgc caaaggaact gtcaatacca tcgccagagt
     4621 tgttccgata cgtgccgtag ccatttcaag tcccatagcc aatgccattt ccttgccctt
     4681 gaaccatttc actataatct tggaaacagt gataccagca atctccacac ctacaccaaa
     4741 gatagcatat cccaatgcag ccaacgtcac ctgtgtttta aatccaaaga gcatggcacc
     4801 ttccggaaaa gtagtagaaa tcgcatagta tttcaatcca caaccaaaca ccatcaataa
     4861 gcaagctccc attccggtga aacgaactcc cattttgtcc aaaatgatac caccgaagat
     4921 cagcatcaac aagaatacgt taaaccaacc gtaagcgctt gtgaagaatc cataatcaag
     4981 actatcccat aatagttctt tctcaagcat gggttttaga ggagacatta cgtcggtgag
     5041 gaaatagccg catagcatag taaatgcgac caatgctaga acactccatc ggagtacggc
     5101 ggagtcattc aatttctgtt tcaaatgttc tgtcattgtt atatttaaaa aagtagttaa
     5161 taatcttata cagccaacaa aggtagttaa atctcgtttg tttctatcac aaagagattg
     5221 tttttacaag aaaaagttaa gtgcggatta cactgaccac gcggaatatt gaaaatccgt
     5281 gtaatctgcg taatccgcac ttaaatatca aagaaatgca gcatccgtct gcaccttccc
     5341 attaatggtt ttaccccaaa gtcttacctg acgacggagt gaattactct gctgcaggag
     5401 caggagtttc agtagccggt gccggagttt ctgtagcagg tgcattggta gcaggagctt
     5461 cagtttgcgg cgcagccgta cctgcgggta agttatacgg gttagtctgt tgttctttct
     5521 gtgcctgttc caacactgca tctttaacaa ctgcagaacg aggaactaca taagcagtag
     5581 caatgctcat tacaaccata aagatggcca ggccccatgt tgctttttcc agaaagtctg
     5641 tagtcttgcg tacgcccatg atggcgttag atgaagagaa accagaagca agtccgcctc
     5701 cttttgagtt ctgaatcagc acgatgaaac acatcaacaa ggctgcaata accattaaga
     5761 taacgaataa taagtacatt tttagttatt ttgaattagc gttaataatc aatttctcca
     5821 aaaatctgat ttggtctgca aagtaagcat ttttttttgg atatttcaag cttaattttt
     5881 taattatttc aagagctttt gaatatcgtt gctgtttaac atagattttt gccaaagttt
     5941 ccgtaaaaca gctgtcatct tcctcttctt ctttcatcgt ttcttcttcg gtaagttcgt
     6001 ccgaagaggt tggcgaagat ggcatttctt ctcttaaagg tttcatgcag aggggagagt
     6061 cgctctcgct cttttctata aagtcgtcaa tcagttcgaa gcctttgagt ttgggcgttt
     6121 cttcggccgg ctgttccgtg gctggagtct cctccaaaag ataagaagtg taatccatcg
     6181 aatagtcgaa actggtccgg gcagtcacct cttcgggtac tgtggacaag aaagcgtcga
     6241 tcaatgctaa tgtgcggtct acggacggtt cgtctttcag cacctccgtg agaggtactc
     6301 cctttttccg tgcctgcaca tcatagcggt caccttcaat caaccggaac aactgccgtc
     6361 tgtctgcaat gtaaagaact gctttccgca gttctccacc gaaactaata tcatggagaa
     6421 tatacagatt cttcagatac agcagacgaa gtgactgaaa atacggatac ctcgcaagaa
     6481 gattgcgcag ttcgtacaaa gtatccctat tcagcgtctc gggatgctga atccattgtt
     6541 gaaagttaac agaagtcatt tatattacca gtttgctaca gttgcattaa aaatttggtc
     6601 ggtgatctct ttagacattt cagcaatcaa tccgtcctgt acggcagtca acaactgggt
     6661 agagtcgtag gtacggaacg cagaaaactg ttgttcaaag tcttcggcat gattggtgtt
     6721 gttgacaaaa cgcacattga cggtgatagt caacttcgtc tccgaagaat aaccgtcggc
     6781 agatactgcc tggttgtact gattgtaccc tgtgatttct ccgtcaatct gcaagtcggc
     6841 attttgactc ggcttgagca gttgcagacg ggtctgccga atgaagatat ctttcaggtc
     6901 ctcattgaat ttggttgcca acggagcata tacatactcc gacttgatcg ggaagtcggc
     6961 tatcgaaatg gtctttacct tatcataatt gatagacgat ccgttaaact tataggaaac
     7021 agtgcacgca atgactacca acggcaagcc gaacagtagc aaagggcgta ttattttctt
     7081 aatccaattc atattctttt atttttctat aaagtgtacg ctcggaaata ttcaagtcct
     7141 tggccgcact cttccgcttt ccgtgatgcc tttcaagtgc tttgcgtatc atttcttttt
     7201 ccacttcgtc cagtgacaaa ggaggttctt ctacatattc ttccgtgtct tgtatgtcgt
     7261 catcatcctt gcaaaccgca ggctgcatgg tatgaatgat cgcaggtacc gaaggctggt
     7321 gtgtcgtcac taccggagta gtaaccaccg ttcccacttg tcctacctgt cccacctgtc
     7381 cggcacgttc cgccatcagg ttgtgcacca tcttcttcag ctccgccact tcctggcgca
     7441 tatcgaacag aacagaataa agaatctccc gttcgctctc aaagccttta ctctcacgcg
     7501 ttcccatcag cgcgggaaga cgttgcgtat tttgtgcggg aagataattc tgcaagatag
     7561 cagcagagat ctccctgttg gtttcaatga tagatatttg ctcggtgatg ttcttcaact
     7621 gacgaacgtt gccgggccac aggtaagcca ataactcttt cttcgcatcc tccgtcaact
     7681 ggatagcagg catccggtat ttctctgcaa agtctgcgga aaacttacgg aacaacaaaa
     7741 gtacatcgtc accacgttca cgcaaaggcg gtatttggat aggcaccgta ttcaaccggt
     7801 aatataaatc ttcacggaaa cgtccttctg caatcgcttg tgtcagattg acattggtag
     7861 ctgccacaat acgaacatcc gtcttttgca ctttggacga acctactttt ataaactcgc
     7921 cactctccaa cacacggagc aaacgcgcct gggtaggcat cggcaactcc cctacttcat
     7981 caaggaaaat agtaccaccg tcggcttcgc caaagtaccc tttccgttcg ccaatcgcac
     8041 cggtaaacgc acccttctca tgcccgaaca gttcggaatc aatcgtgccc tccggaatag
     8101 caccacagtt gacagcaata tactgtccat gcttcctccg gctatattga tgaataatct
     8161 gcggaaaact ttcttttccg actccacttt ctccggtaat cagcacagac aaatcggtag
     8221 gagctacctg aatggcaaca tctatggcgc gcgacaatgc ttcggtattt ccaataatac
     8281 cgaaacgctg tttcacttgt tgtatctctg ctctcgtcat cactcgtttt taatcttcgt
     8341 ctactgtatc cagcttcagt ttatcactat cgtcacgttt ctcgtaatac tgtttacgca
     8401 acggattggc acgagccact ttttcccgct gacgattacg gaacacatcg atggcaacat
     8461 agattgcctg acggaaagaa tcttcacaag ccaatccctt gcctgcaata tcgtatgccg
     8521 ttccatgagc cggagaagta cgtactaccg gcaggcctgc cgtatagttc accccgtctt
     8581 ccatagccaa ggccttgaac ggagccagcc cctgatcgtg atacatcgcc aggataccgt
     8641 caaaatgagt ataattgcct gaacccataa agccgtcggc cgcataagga ccgtagcaaa
     8701 ggattccttt ctcttccatt tctttcatgg cagggataat cacttcctgc tcttccattc
     8761 ccaacaaacc accgtctccg gcatgaggat tgagagagag caccgcaata cgcggagcgc
     8821 cgataccgaa atcctgtttc agacaacgat ggaatatcat cagtttctcc tgaatcagtt
     8881 ctttggtaat cgtagtcgcg atctctctaa cagggatatg tgtcgtcacc aaagccaccc
     8941 ggaagtcatt cttcatcaaa atcatcaatg acttatcacc attgcccaga cgttcttcga
     9001 tatattccgt atgtccgggg aaggagaact cttccgactg aatcgtatgt ttgttgatcg
     9061 gagctgttac gataacgtct atcagccctt cgcgatattc ttcgatggca cgttccaaag
     9121 ctcccagcgc agctttaccg gcttcgggat cgggtttgga aaattccact ttcacctcat
     9181 catccgtaca gttcaccacg ctcaaacggt tgtaccccgc ttcggtagca gagttgacaa
     9241 tgctgaaatt ggtctgtata tccagcgctt tgcgatgata agccgctact ttcggtgagc
     9301 cataaatgat cggagtacat agttccaaca tcgtagggtc ggaaaatgtc ttaagaatca
     9361 cctcatagcc caccccgtta atatctcctt gggtgatacc tatccttatc ttgttatctt
     9421 ccatgttttt atttattagt ttgttccgct tccttagatg cttctcccaa tggaatctga
     9481 ttctgctgaa cttcattcgg aagtttcagt gtatacagag atgcttccat ctggcgtacc
     9541 aggttgcgtt tcattttatc aggtgaataa acaaatattt ctgctgttat aattcgttgg
     9601 tttttctcgt ccagacgagt atgagataca tacgggccac ccataaagtc gcccttcata
     9661 cgccacaggc cacgtgcttc cattgtgtag ctgttctgta cattgatcgg acggacatcg
     9721 gtcagcaaac tatcggtcga catataaacg ccttccttga atccggggat attggctttc
     9781 atcacggagt cacgtttgtg cacaaaatat tctttggtaa acgtatcctt gtcagtgtac
     9841 ggataagagt acatcacaaa gttacggtcg gcactacctg tgttggtaga ggcccaaaag
     9901 aaatcatccc cggtctttga attagccagt tcggcatcca cccagatgtc gcatccgaac
     9961 aaactgtcca ctttctgcga aatgaagtta ctatgcttcc cttccaggaa cgtaatctga
    10021 cggttcattt ccgcacgggt aaagaagtcg acaatcgtct ttttgttctc ttccacaaac
    10081 ttctcgaact cttcttcgtt cggagcctgg atagtcaata tcatctgcgg attggcatac
    10141 acgtccttcg catatttgaa cgaggctttc gtatatatat cctgtatatc tacaataata
    10201 atgttacgta tcaacttcag cgtagaatca taatctttcg gtgaagtata cataatccgg
    10261 aaagaaggtt ccgactgcgg caaaccgggc atatcagcat cgagcgcatc atgtaaagcc
    10321 cttccggcag cacgatccca aacaccgtga tctactacaa ccaaaagctc gtaagcacga
    10381 ccactagagg tgtgatttcc tttcagacca caagatgcaa cgacaaaggc taccaaagcg
    10441 atgcataaaa taaaagagta ctttttcatg atgttcggtt ttatatatta actttcatta
    10501 tttttctcct gtttcgctgt cgacagcata ccgcaagcgg caaaaatatc ttcgcccctg
    10561 gatgaacgga tagtggtgaa aagtccgtgt gacgtcagat aatcacgaaa acgggtcatc
    10621 gtatccatgt ccgctccctc gaggtctacc cccggtatgg catgaaaacg aatcagattc
    10681 accctgcaat ccagcccgcg aagaagtttc agcaactctt tggcatagac ctgcgaatca
    10741 ttgagccctt taaaaacaat atattcaaac gaaagtcgac gttgtttact aaaatcatag
    10801 ttttttaaca gttccaccat ttcggtgatt gaaaacgcct tttccgccgg cattaattca
    10861 gcacgctgaa cggtcagcgg agagtgaagg ctgatggcaa ggtgacagtc attttcttca
    10921 ataaaacgct gcaatccttt ccgtagcccg actgtagaaa gcgtgatacg tttcggactc
    10981 catgcgtaac cgtaggtagc ggtcagtagt tccaatgctt tcaatacctc atccaggtta
    11041 tcgagcggct cgcccattcc catcattacg acattagtca gtttgtcccg ttccggcagc
    11101 gaatgaatct gattcatgat ctggctggcg gtcaggttag cggtataccc ctgtttaccg
    11161 gtcatacaga acttacagtt catcttgcaa cctacttgtg acaacacgca caacgttgcc
    11221 cggtcatcat ccggtatata aaccgactct acaaaatggt tctcacccac tttataaaga
    11281 tacttcaccg taccatctac agagcgcatt tcatctaccg gagcttccgc tcccacctca
    11341 tagttctgct tgagcaactc ccggtgtttc aatgacaaat tagtcatatc atcaatcgag
    11401 gctaccttct tttcgtaaag ccaggatgca atctgcttgg cagcaaagcc gggcataccc
    11461 agtctttttg tcaatgattg aagctctaca agagtcattc ctaaaagggg atatttagac
    11521 attcttcttt ctgttgatag tttatatctg caaatgtaag gaaataaagt cgatttccgt
    11581 atagcaggaa tgtaaaagtt aacaaaaaag ggaagtatgc ctccgttatg attcaaccac
    11641 gctgatatat tgaagtagct tttgcgccat ttcagaatcc tcgccattct ttttcacttc
    11701 atgaccgtac gcctcacgga aacaagccag cgcctcttcc cgttcattac aaaagctgtg
    11761 caaaacccct aagttctgac aagccagaat cgtatcttct tcctcccatc ccaaatactt
    11821 ctttcgcagt tcgaactctc tgaagaaagc ctctttcgcc attggataat tctccaactt
    11881 cacataagcc tgtgctttgt aataatatac cagacaggaa gcattagggt cagcatcatc
    11941 gtgaatatcc aaagacgtcg caatacgaat cacgttatca tagtctttat tcatgtaata
    12001 ctgctgcata atatcacatc tcaatgcctc atatcggaca gtcagttccg ccagacgcgg
    12061 tttttcgctg aaatacattt catgcagaag agactcacgg aagaataaag tagacgcctg
    12121 ctcatcgcca cgttcattca tcatccgttt gaattccctg catagataat acaactgttt
    12181 atgacaagcg acgatctgtt ttttattatc tatctgtata gcaatgtcca acgcctgatt
    12241 catcagcatc catgcttcat cgtatcgttt gatataataa agacatttac cctgcatacg
    12301 caaacattta gccactccac cggacagtct gccattcaat gactcgtgca tttcagcaac
    12361 tttccggaat ttctcggcag cactctcttc ctcatcctta tagtaatcac aataagccag
    12421 atattcggaa agttcaatga cttctgcctg actcttctcg tcagcagaag ccgcatgata
    12481 atcaagcgcc ctattcagat agatcactgc ttcattgtat tgctcattgt agtaatatgc
    12541 cagagctaga tttcggcagg tgttggcaat ctccagttcc ggagtcggta caatgttttc
    12601 ctgcatcacc aatgctttca ggaaacagtc gcatgccgtt tcgtattctt cattacgggc
    12661 atatcggcat ccctcattca tcttcaatac cgacttggca atgagtggca tagcagcacc
    12721 ttccatactc ttctcactca cagcagctgc cgccttcgtc agatggaaag aactgctcaa
    12781 gaaagtagcc atatcattag caataacagg aattaaaaaa gaatcgatct catcaaagtc
    12841 caattcggca tagacttcag gcgtaacttc aggattgtcg ttcatgatcg ctttccagct
    12901 atcttccaac aaagaacgat tcgtgcgata cagaatctcg aaaatctcca catcacaaat
    12961 ccaatccttc aatatatccc attcttgcat cttatagcat tgataggtaa tctccacttt
    13021 atagcgatac gaatcatggt agcagaactg tttcatgcga tagttataat cggcaaaagt
    13081 caacggatgg gaaaggattt cttcctcatc cagcagagcg gaaataattt catggcgact
    13141 atcatctata cattcgtcat cttgagcgaa atagcgttcg atcgcctcta ccatttgtgt
    13201 gtcaccaatg caatatcgtc ctcctttgtt ggtgagccag ctgctcattt ccactctcaa
    13261 ctgcgaccaa agtatctgat taatgtctgc catgctcttc acttcatctt cggtaaatcc
    13321 ttctaaagta agtgaaagca tcagaagcgt tcttccaatc tcttcggaac cataatcagc
    13381 cgacaaacgc cgtagcacac tgtcatagaa ttgcccaacc tcattgagcc ggcaatatcc
    13441 acgcatatat tcattgagag catcgtactg accgaacgaa accagctcgt tgagcaatac
    13501 acttaaacag cgcggttgtt tagccagcac ccacgaagca agaatatctt cctgctgtgc
    13561 agacaaagcc ttggagtaag tagacaaata ttgctttgag aacgacttgg catccgcctg
    13621 tgaaaagcca ttcaactgga aatgagcgca
//
