LOCUS       c00047_gnlPro..        24536 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OPOIIMFC_47.
ACCESSION   c00047_gnlPro..
VERSION     c00047_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 12:58:22
            Original ID  :: gnl|Prokka|OPOIIMFC_47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1105
            Orig. end    :: 25641
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24536
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[11105:15641]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14536
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24536
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24536
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             573..1094
                     /locus_tag="ctg47_3"
                     /transl_table=11
                     /translation="MSFLELARKRCSIRKYAPKNVEQEKIDYILEAARLAPSAVNYQPW
                     YFVWVQSAEGKAKLQECYPREWFKQAPYYLIVCGDHQQSWKRGDHKDHMDIDTAIATEH
                     ICLAAAEQGLGTCWVCNFDTELCRKHFKIPETIEPVVLIPFSYPSDPALFDETPKKRKP
                     IEEIIKRESF"
     CDS             1096..1662
                     /locus_tag="ctg47_4"
                     /transl_table=11
                     /translation="MLYIEVLLLAIGLSMDSLAVSVTGGAVLKNNCTAGNIIKIASVLG
                     IFQAGMTVIGYTMGLGFEKYICAFDHWIAFTLLLYLGGKMIYDSTKEEEEDGKFDPLCN
                     RTLCGLGIATSIDALAVGISLAILKSPLLLQASTIGVVTFAISAFGVYFGNRFGKRIDL
                     KLDLIGGLILIGIGTKILIEHVFFS"
     CDS             1860..3431
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ILVD_EDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_5"
                     /sec_met_domain="ILVD_EDD (E-value: 2.5e-177, bitscore:
                     581.7, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDEAGIGIKEKGGRAANYFVTDICDGEAQGHDGMNYSLVSRDIMA
                     AMMEIHVKATPFDAGVFIASCDKSVPAHLMAIARLDMPAIFMPGGIMKAGPNLLTLEQI
                     GTYSAQYERKEITEEQFMVYKRDACPDCGACSFMGTASTMQVMAEALGIALPGSALIPA
                     HLPELKETARKAGERALGLAKEELKPSDIMTIQAFENAIMVHAAIAGSSNSLLHLPAIA
                     HELGIQLSPDLFDKIHRKIPYLLNIRPSGFWPGEYFWYAGGVPAIMEEIKEFLHLDVMT
                     VTGKTLEENLKDLQLNGFYENCHKYLPALGVKVGDIIKPFHTPIKAQGAIAILKGNLAP
                     EGAVVKHSAISPRLMQVTLKARVFDCEENAIEAVLQKKIHPGEAVFIRYEGPKGSGMPE
                     MFYTTEAIASDPELVETIALITDGRFSGATRGPAIGHVSPEASEGGPIALVENDDLIRI
                     DIPARTLDIIGTDSIERSVEEIEKILSERRAHWIKPESQYKKGILDIYTHNSVSPMKGA
                     YMEFFM"
     CDS             3457..4485
                     /locus_tag="ctg47_6"
                     /transl_table=11
                     /translation="MRKNITILVSLLILSLTACSDKGQYFEESGSVFHTSYHIKYKAKQ
                     ILTDKIDSELQRFNLSLNPFNPNSTIAKVNNNEDVEVDEWFTEVFNKAEEISQKSGGAF
                     DITCAPLINLWGFGFSKMDSVTPQMIDSIKAFVGYQKVRLEGKKIIKEDPRILLNCSSI
                     AKGYACDVIARLLEKEGVKNYMVEIGGEVTMKGVNQQGDCWRVGINKPEIGTSGVTNDV
                     EEIVQLCQKGGVATSGDYRNFYIKDGKKYAHTINPATGYPAGQNILSATIVAEDCMTAD
                     AYATTFMVLGVEKAKLLAQSIPQIEYFIIYADNNGQQKVTYSKGMLEYLPNRKTLAILE
                     NP"
     CDS             4494..4871
                     /locus_tag="ctg47_7"
                     /transl_table=11
                     /translation="MKRYLNQLECKILRAGDSLFNTTTTDNLLIFVFSGKLIIYSQEGT
                     HIAEVAKDHFMLLAQNTNHKVIASAPTRLILIHAGSLSDMIINDPEWNVEKPVVLPIPP
                     ALAHTLNQIEYYMKDKYFTLN"
     CDS             complement(4874..5455)
                     /locus_tag="ctg47_8"
                     /transl_table=11
                     /translation="MLENLKKYKIVLASNSPRRRNLLSGLDIDFEVRVIPDIDESYPDS
                     IDSMEIPLYIARSKAEAYKSTMADDELLITADTIVWTFDGVMGKPANREEAYAMLHALS
                     DHVHQVITGVCIMTKDKNVGFSVESAVCFAKLGDEEINYYLDKYKPYDKAGGYGIQEWI
                     GYIGVEAINGSFYNVMGLPVQKLYQELKHF"
     CDS             complement(5474..5917)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_9"
                     /sec_met_domain="HAD_2 (E-value: 1.3e-08, bitscore: 26.3,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVNIKDGYALQLAVKKGYEVAIITGGYTEAVQIRFSRLGIQHI
                     YMRSAVKVHDFKDFMEKTGLSPEQIMYAGDDIPDYEVMTQVGLPVAPADAAPEIKEIAK
                     YISSRRGGEGVARDVIEXXXXRCGLKDTGSARRLLGGKILVNV"
     CDS             complement(6015..6782)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_10"
                     /sec_met_domain="F420_oxidored (E-value: 2.6e-09, bitscore:
                     28.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVFVGAGNLATRLSLEMRKSGMSIGQVYSHTSEHAKILADELG
                     CGWTVVPEDIVEDADLYVFSLKDAVLQDVIARVKPNNGLWVHTAGSMPISVFEGLTARY
                     GVVYPLQTFSKSREVDFKKIPFFLEANSSEDEKVLGEVARALSSDVRFLSSEKRKNLHL
                     AAVFACNFTNHMYALAEKILEEQQIPGEVLLPLIDETAAKVHVMSPARAQTGPAIRYDE
                     NVINKHMAMLKDPDMRNLYELISRSIHKEARHE"
     CDS             complement(6779..7234)
                     /locus_tag="ctg47_11"
                     /transl_table=11
                     /translation="MAPASKRSNPWQFVVVEDKEMLKKLAGCKKNGSAFLEGCALAVVV
                     LANVMESDVWIEDASVASIYMQLQAEDLGLGSCWCQIRNRVTEDEADSNNYVRSLLDIP
                     YQLDVLSIIGIGYKDQVRKPFDESHLQWEKIHIGKFSLPEENKEAEE"
     CDS             7461..9872
                     /locus_tag="ctg47_12"
                     /transl_table=11
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVRV
                     KNTLIGSMTNEKGYYSFSISPGDSISVIYSCLGYNKAERIIPSAQADMRLNVQMNYTSF
                     DLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQYSVR
                     GGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSV
                     LDITYKKPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTDAEYDP
                     KFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVYFDGRER
                     DRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAENPDDDASA
                     AMSVGRYHEHARNRLNSTVMNVGHYGMARLLNNTLKWGATVQMEKINDKISEWEKRDSS
                     GYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVAGVRGSYWTYN
                     KEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRRVDKDKNGNNITVLNKDLK
                     SQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRYYGENCAKGYAM
                     GLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISLFFQDYFPGYKRV
                     KLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGTDAIMDRGFFRHLK
                     NIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVRLIVDF"
     CDS             10001..10411
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_13"
                     /sec_met_domain="Glyoxalase_4 (E-value: 8.1e-27, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             10448..12001
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_14"
                     /sec_met_domain="CT_Btheta (E-value: 3e-292, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12023..12916
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_15"
                     /sec_met_domain="OAD_gamma (E-value: 4.8e-13, bitscore:
                     40.9, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLLMVLFSMGAKAQLTTSVKLNEVLVVNEDNFVDDY
                     GKRHPWFELFNNSAGTVDLRGCFLTNDKSNPRKYMIPKGDVLTKVPPRQHLLFWADDQP
                     TKGTFHVNFTFDPNKDNYLALYDSDGTTLIDEVTIPAGQKADVSYGLDLDGVGNWSILD
                     KVTPSTNNLTLDSNAKLENFQRNDPWGIGMTITAMAVVFLGLIILYLVFKQIGNAAIKA
                     SKRNAQKAAGTGAAVSANIGQESGEIFAAIATALYEMSDDNHDIENTVLTIHKVQRSYS
                     PWSSKLYSLRQTPNKK"
     CDS             12940..13371
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.7; E-value:
                     3.5e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_16"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.1e-20, bitscore:
                     63.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNTYKVHINSVVDDVAEVEVNGTPYNVKMEKPAKKQ
                     MVTLKRPAQAPTNASGEPVITRQAAPSVAGAVKSPLPGVILSVDCKVGDTVKRGQKILV
                     LEAMKMENNINADRDGKIVEIKVNKGDSVLEGADLVVIG"
     CDS             13376..14536
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_17"
                     /sec_met_domain="OAD_beta (E-value: 1.9e-153, bitscore:
                     501.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLQFLGENIQIFLSYTGFANATPGHIVMLLVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQLGIYEEGSVLNILYQGVKQGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYIIALQMGFDPSQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERVIRMKPPRAVSQTEKIVFP
                     IVGLLLTAFLVPSGLPLLGMLFFGNLIKESGVTRRLAETARGPLIDVITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKFFNLFLKEGNKINPLIGNSGVSAVP
                     DAARISQNVGLEYDPSNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(14818..15534)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_18"
                     /sec_met_domain="Peptidase_M22 (E-value: 1e-27, bitscore:
                     88.7, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLILNIETSTSVCSVALSEGEEVVFEKASFEGPSHAALLGVYME
                     EALEAAKSKGIKLDAVAVSSGPGSYTGLRIGVSVAKGLCFGYGIPLIGIHTLDILASAA
                     IRKNKEEADCLYCAMLDARRMEVYSSIYDSHLNTIRATTADIVDADSYASFLENGKVCF
                     FGDGAAKCETVITSPNACFIDGIYPLAVNMASLSQKAYDDGRFENVAYFEPFYLKEFQA
                     TIAKNKVLNEALGKNK"
     CDS             15736..16596
                     /locus_tag="ctg47_19"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKDKEMEL
                     RSLLLQSLERGKVEFNIFIEYIGKDTPTQINLAAVENYYNQIKEIAEKLNISVPNDWFQ
                     TLLRMPDAIKSETVEPDESEWEVVLETVKDAIKHLCDFRIQEGAMLQKLFEQKIANIAT
                     LLKEVEKYEGERIEKIKARIMDNLQKIAEKDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYFISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMKDELEQIKEQ
                     VLNVL"
     CDS             16611..16982
                     /locus_tag="ctg47_20"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINYLLKQDLHLRFSISATSRAPRGTE
                     KNGVEYYFLTPEEFRSRIANGDFLEYEEVYTDKYYGTLKSAVERILNEGXXXXGRRMQY
                     QEILWRPCPVCLYPTSLHR"
     CDS             17167..17346
                     /locus_tag="ctg47_21"
                     /transl_table=11
                     /translation="MPNIFKNTRFMMGLSIVCGIASLVLGGISLYYKEYIIGGALIFNI
                     FICFINYKGWQKKG"
     CDS             17358..17933
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_22"
                     /sec_met_domain="CTP_transf_like (E-value: 3.5e-25,
                     bitscore: 80.1, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLKIGIYSGSFNPIHIGHLALANWLCEFEGLNEVWFVVTPHNPL
                     KKKDDLLDDSLRLEMAQAAIDGYPKFKVCDIEFHLPKPSYSIDTLRALSSNYPDRDFYF
                     IMGADNWLLFPRWKEYEKILQNYKLLIYPRLGFDISIPTIYPNVKKVDAPLMEISSTFI
                     RNAYQTGKDIRFFLPEGVRPYFGSVANQ"
     CDS             18414..18662
                     /locus_tag="ctg47_23"
                     /transl_table=11
                     /translation="MNSLYMVEGVIGAVGGAIFVQTNKYLQAGMENEDFYGWGLEDGER
                     HYRWLSFGYRIDGVRAVYSICLIPGIKTGCKDKIIGS"
     CDS             18843..20573
                     /locus_tag="ctg47_24"
                     /transl_table=11
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKET
                     FKDDAEPRPVSIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPDENKDTYNVVF
                     KKLLDIGDFVGIKGFVFRTQMGEISVHAQELTVLSKSLRPLPVVKYKDGVAYDGFNDPE
                     LRYRQRYVDLVVNDGVKDIFMKRAAIIKTMRTALDEAGYTEVETPILQSIAGGASARPF
                     TTHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYV
                     QYKDYNWMMSFTEKLLERICIAVNGTSESTIDGKTISFKAPFRRLPILEAIKEKTGYDL
                     EGKSEDEIRTICKELKMEIDDTMGKGKLIDEIFGEFCEGTFIQPTFIIDYPVEMSPLTK
                     MHRSKPGLTERFELMVNGKELANAYSELNDPIDQEERFKEQLRLSEKGDDEAMFIDQDF
                     LRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTAKKDNADKYVALGI
                     SEEWIPALQKAGYLTVDTLKEANANKLRQDLCELNKKYKLELQNPTVQEVEAWIANVGE
                     "
     CDS             20586..21581
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_25"
                     /sec_met_domain="F420_oxidored (E-value: 1.1e-09, bitscore:
                     30.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 3.2e-35,
                     bitscore: 112.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDRIEEFKQ
                     LGHNPCYLTAVKFDTNKINFYSNINQAIKDSDTLIFATPSPFLKQHLKKVKTSLKDKFI
                     ISAIKGIVPDENMLITDYFAEYYKVPTENIAVIGGPCHAEEIALERLSYITLACSDIDK
                     VRTISPVFKNQYLKNSFCKDVTGIEYAAVLKNVYAIAAGICHGMKYGDNFQAVFISNAI
                     EEMRNFVDAVHGLERDITDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKTAQLEMEM
                     IAEGYYGTKCMREINEKYKVNMPILDAVYDILYEKKSPTTVIRQLTETFK"
     CDS             21590..22933
                     /locus_tag="ctg47_26"
                     /transl_table=11
                     /translation="MKNISLNIDKALGTVSKEQVYAQEAKAMECIATLHNGNGAGNDFL
                     GWLHLPSSITDTELADIENTANVLRSKCEVVVAIGIGGSYLGTKAVVEALNNSFDWLQN
                     DRKNPVMLYAGHNIGEDYLYELSEVLKGKQFGIINISKSGTTTEPALAFRILKKQLEDA
                     VGKEEAKHRIVAITDAKRGALRTLADQEGYKTFVIPDNVGGRFSVLTPVGLLPIAVAGI
                     SIRDLVAGAVSMEKATDASVPFADNMAAIYAATRNELYKSGKKIEILANFHPKLHYIAE
                     WWKQLYGESEGKDGKGIFPASVDLTTDLHSMGQWIQDGERTIFETVISVEATDHSVLVP
                     TDEADLDGLNFLAGKHVDEVNKMAELGTQLAHVDGGVPNIKVTMPEVSAFYIGQLFYFF
                     EKACGISGYMLGVNPFNQPGVEAYKKNMFALLNKPGYEKESEAIKARL"
     CDS             complement(23004..23279)
                     /locus_tag="ctg47_27"
                     /transl_table=11
                     /translation="MNRGELVQSLVEETGLPKNVVRTVVNALPTVVAKGIREGESISMK
                     GFGSFVPWQQSERLARNPKTGEEVMITPRVSVKFKAGSDLLKELNE"
ORIGIN
        1 gacccgttgt ctaagacgat ccccacgaaa ttattcaacg cgacagctcg taaattctcg
       61 ggaataaaga acttacacga tttcaattgc ggattgaaag cgtataagaa tgttgtcatt
      121 aaaaatatag aggtgtataa cgatatgcac cgttacatac cttatttagc taagattgcc
      181 ggatttcaca agattggcga gaaagtagtg aaacatcaag cccgcaagta cggaactact
      241 aaattcgggt tggatcgctt cgtgaacggt tatcttgatt tgatcacgct ttggtttact
      301 tccaaattcg gaaagaaacc gatgcacttc ttcggtttat ggggaagcgc tatgttcttc
      361 attggtttta tcgctctagt aatcgtactc agcatgaaat tgatctcgat gtactctgga
      421 gatctaagac ctttggttac aagttcccct tatttctata tttcattgac agcgatgatt
      481 ctgggaaccc agatgttcct agcgggcttt atcggggagt tgatttcccg caattctccg
      541 aatcgcaata actataaaat agaggatgag atatgagttt cctagaatta gcgagaaaac
      601 gttgctctat ccgaaagtat gcccccaaaa acgtagagca agaaaagatt gattatatcc
      661 tagaagcagc tcgtttggcc ccttcggcgg taaattatca accttggtat tttgtatggg
      721 ttcaaagtgc ggaaggaaaa gctaaattac aagaatgcta tccccgggaa tggttcaagc
      781 aagcgcctta ttacttgatc gtttgcggag atcatcagca atcttggaaa cggggcgatc
      841 ataaggatca tatggatatc gatacggcta tcgccacgga acacatttgt ttagccgctg
      901 ccgaacaagg attgggtact tgttgggttt gcaatttcga cacggagctt tgccgtaaac
      961 attttaaaat tccggaaacg atcgagcctg ttgtactgat accgttcagc tatccttccg
     1021 acccggcatt attcgatgag actccaaaga aacgtaagcc catagaagaa attattaaac
     1081 gggaatcatt ctagtatgtt atacattgaa gttctgctac tagcgatcgg cttatccatg
     1141 gatagcctag cagtatcagt taccggcggc gcagttctta agaacaactg caccgccggt
     1201 aatattatta agatagcgag cgtgctcggt atattccaag ccggaatgac cgtgattggt
     1261 tatacgatgg gattaggatt cgaaaaatac atttgcgcct tcgatcattg gatcgcattt
     1321 accctcttgc tttacttagg tggaaaaatg atatacgata gcacgaagga agaggaggaa
     1381 gacgggaaat tcgatcctct atgtaaccgg acattatgcg gattgggaat agcgacaagt
     1441 atcgatgccc tcgccgtagg aatctctctg gcgatcttaa aatcaccgct cttgctgcaa
     1501 gcctcgacta tcggtgttgt caccttcgct atctctgcct tcggtgtcta tttcggtaac
     1561 cgattcggca agagaatcga cttgaagctg gacctcatcg gaggtttaat cttaatcggt
     1621 atcggtacaa agattttgat agagcatgta ttctttagct agggatacct tattgaataa
     1681 ataaccttat acattaatta atagacatga aaagccagca attacgaaaa ctagcgccgg
     1741 agctggattc actccggcta ggcagcggtt ggaaaatcga cgaattgagt aaaccgcaaa
     1801 tcattgtaga aagcagttac ggacatagcc atccgggaag cgcccatctg gataaattga
     1861 tggacgaggc cggaatcggt ataaaggaaa aggggggacg tgccgcaaac tacttcgtca
     1921 ctgatatttg tgatggagag gcgcagggac acgatggtat gaactactca ttagtctccc
     1981 gtgatatcat ggccgccatg atggagattc atgtaaaagc gactcctttc gacgctggtg
     2041 tctttatagc cagttgcgac aaatccgtcc ctgcgcattt gatggcgata gcccggctag
     2101 atatgcctgc tatattcatg cctggtggta taatgaaagc cggtcccaac ctactcacgt
     2161 tagaacaaat cggtacctat agcgcccaat acgagcgaaa agaaataacg gaagaacaat
     2221 tcatggttta taagcgtgac gcatgtccgg attgtggagc ttgctctttc atgggtaccg
     2281 cctctacgat gcaagtaatg gcagaagcgc ttggcatcgc tttaccgggc tccgccttga
     2341 tccccgccca tttacccgag ttaaaagaaa ccgcccgtaa agccggagaa cgtgcgctcg
     2401 gactagcgaa agaagagtta aaaccctccg atatcatgac gatacaagcg tttgaaaatg
     2461 cgatcatggt acatgccgcc atagcgggtt ccagcaacag cctgcttcat cttccagcta
     2521 tcgcccatga actgggaatc cagttatcac cggatttgtt cgacaagata catcgtaaga
     2581 tcccctacct tttaaatata cgtcccagcg gtttttggcc cggcgaatat ttctggtatg
     2641 cgggaggcgt accggcgatc atggaagaaa tcaaagaatt cctccatctc gacgtcatga
     2701 ctgttaccgg caaaacattg gaagaaaact taaaagattt acaactcaac ggcttctatg
     2761 agaattgcca taaatatctt cctgccctag gagtaaaggt tggcgatatt atcaaacctt
     2821 ttcatacacc gatcaaggca caaggagcca tcgctatatt gaaaggaaat ttagcgcccg
     2881 aaggggcagt cgtaaaacat tcggcgattt caccccgctt gatgcaagtc accctgaaag
     2941 cgagggtatt cgattgtgag gagaacgcta ttgaggcggt attacaaaag aaaatccatc
     3001 cgggagaagc ggtatttatc cgttatgaag gaccgaaagg aagtggaatg ccagaaatgt
     3061 tttatacgac agaagcgatc gcctccgatc ctgagttggt agagaccatc gcattgatca
     3121 ccgacggtcg tttctccgga gcgacccgag gcccggcgat cggacatgta tccccggagg
     3181 cttccgaggg gggaccaatc gccttggtcg agaacgatga cttgatccgt atcgatattc
     3241 cagcgagaac attggatata atcggtaccg acagtattga gagaagcgtg gaagagatag
     3301 aaaagatcct atccgaaagg cgtgcacatt ggataaaacc agagtcacaa tataaaaaag
     3361 gaatccttga tatttataca cacaatagcg tctcccccat gaaaggggca tatatggaat
     3421 tttttatgta agttcgcgac ataaaatttc ataatgatgc gcaagaatat taccatatta
     3481 gtcagcctgt tgatcttatc gcttacggct tgctcggaca agggccaata tttcgaagag
     3541 agtggttctg tttttcatac aagttaccac atcaaataca aggccaagca aatcctaacc
     3601 gataagatcg acagcgagct gcaacgtttt aacctctcct taaatccttt caaccccaac
     3661 tccacgatcg cgaaagtcaa taataacgag gatgtggagg tagacgaatg gtttaccgaa
     3721 gtattcaata aggcggaaga aatctcccaa aaatcaggag gagcttttga tattacttgc
     3781 gctccattaa ttaatctatg gggattcgga ttcagtaaga tggatagcgt aaccccgcag
     3841 atgatcgata gcataaaggc tttcgtcggt tatcaaaaag taagattgga aggaaagaaa
     3901 atcatcaaag aagatccccg gattctattg aattgttcgt ccatcgcaaa aggttatgct
     3961 tgcgatgtca tcgcccgcct gctggaaaag gaaggcgtaa agaactacat ggtagaaata
     4021 ggtggtgagg tcaccatgaa aggcgtaaat caacaaggag actgttggcg agtcggcatc
     4081 aacaagccgg aaatagggac aagcggcgta acaaatgatg ttgaagagat cgtacaatta
     4141 tgccaaaaag gaggtgtggc tacttctggt gactaccgaa acttctacat caaggatggt
     4201 aagaaatatg cccatacgat caatccggcg accggttatc ccgctggaca aaatattctt
     4261 agcgcgacaa tcgtggcgga agattgtatg acagcagacg cttacgctac gactttcatg
     4321 gttttgggag tcgagaaagc gaagctactg gcacaatcca tcccccaaat agagtatttc
     4381 attatttatg cggacaacaa cggacaacag aaagtcacct actcaaaagg tatgttggaa
     4441 taccttccta acagaaaaac attggctatc ctcgaaaatc cttaagttcc tacatgaagc
     4501 gttatctaaa tcaacttgaa tgcaaaatac tgagagccgg agattccctg tttaatacca
     4561 caaccacgga taacctatta atcttcgtat tttcgggaaa acttattatt tacagccaag
     4621 aagggacaca tatagcggaa gtggcaaaag atcatttcat gctacttgcg caaaacacca
     4681 atcataaggt tatagcctca gcccctaccc gccttatctt aatacatgcg ggcagtctat
     4741 ccgacatgat cataaatgac ccggaatgga atgtggagaa accggtcgtc ttaccgattc
     4801 ccccagcctt agcgcacaca ttaaatcaga tagaatatta tatgaaggat aaatacttta
     4861 ccttgaattg agattaaaaa tgtttcaatt cctgataaag cttttgcaca ggtaatccca
     4921 tcacgttata aaagctacca ttgatagcct ctaccccgat ataaccgatc cactcctgaa
     4981 tgccataccc tcccgcttta tcataaggtt tatatttatc caaataataa ttaatctctt
     5041 catcacccaa ttttgcgaaa caaaccgcag attcgacgga aaagcctaca tttttgtcct
     5101 tcgtcatgat acaaacgcca gttattacct gatgtacatg atccgacaaa gcatgaagca
     5161 tagcataagc ttcctcccgg ttcgcaggct tccccataac cccgtcaaac gtccagacga
     5221 tcgtgtccgc cgtgatcagc aattcatcat ctgccatagt cgatttatag gcctccgctt
     5281 tcgaacgggc aatatataaa gggatctcca tggagtcaat agaatccggg taagactcgt
     5341 caatatccgg aattaccctc acctcgaagt cgatatccag accagataac aaattccgtc
     5401 gtctcggaga attagaggct aagacgatct tgtacttttt taaattctct aacataacct
     5461 attcgattaa gcgttacaca ttcaccaaaa ttttaccacc caaaagcctc ctcgccgaac
     5521 cagtgtcctt gagcccgcat cgnnnnnnnn nntgctcgat cacgtcccta gctacgcctt
     5581 cgccacctcg ccgggaggat atatatttcg ctatctcctt gatctccgga gccgcatccg
     5641 caggtgccac cggcaatccg acttgcgtca ttacctcata atcaggaata tcatcacccg
     5701 catacatgat ttgctcagga gacaagcccg ttttttccat gaaatcctta aagtcatgca
     5761 cctttacagc gctacgcata taaatatgtt gtattcccaa acgagaaaag cgaatctgta
     5821 cggcttccgt atatccaccc gtaattatag cgacctcata acctttcttc acggccaatt
     5881 gcaaggcata gccatccttg atattgacag tacgcatcgg atcgccattc gggtgaagcg
     5941 gaatcacatc gcaggatagc accccgtcta catcaaagac aaaagccttt atttttctca
     6001 aatcatagtt tatactactc atgtcgagcc tccttatgta tacttcggct aatcagctca
     6061 tatagatttc gcatatccgg atctttaagc atagccatat gtttgtttat cacattctcg
     6121 tcatatcgta tagctggtcc cgtttgggct cgcgccggcg acattacatg taccttagcg
     6181 gctgtctcgt ctatcaaagg tagcaagacc tctcccggta tttgctgttc ttccaagatc
     6241 ttttcagcta gcgcatacat atgattcgta aaattacaag cgaaaaccgc cgctaaatgt
     6301 aagttctttc gcttctcgga ggagaggaaa cggacatcac tggagagcgc cctagccacc
     6361 tctcccagca ccttctcatc ttcagacgag ttcgcctcta aaaaaaacgg tattttcttg
     6421 aaatccacct ccctactctt actaaacgtt tgtaacggat aaaccacccc atatctagcc
     6481 gtaagacctt caaatacaga gattggcata ctccctgccg tgtgcaccca caaaccgtta
     6541 ttcggtttta cacgggcgat aacatcttgg agcacggcat ctttcaaaga gaaaacatac
     6601 aagtcggcat cttccacaat atcttccggg acaacagtcc acccacatcc caattcatcg
     6661 gctaaaatct tagcatgctc acttgtgtga ctatacactt gcccgatact cattccggac
     6721 ttacgcattt ccaacgaaag ccgggtagct aagtttccgg caccaacaaa tacgactctc
     6781 attcttccgc ctctttattt tcttccggaa gagagaactt tcctatatgt atcttctccc
     6841 attgtaaatg ggattcatca aaaggcttac gaacctgatc cttataaccg ataccaatga
     6901 tagacaagac atccaattga taagggatat ccagcaacga acgaacataa ttattcgaat
     6961 ccgcctcgtc ctctgttacc cggttccgaa tctgacacca gcaactgccc aatcccaaat
     7021 cctccgcttg caattgcata taaatagaag cgaccgaagc gtcctcgatc caaacatcgc
     7081 tttccatcac attcgccaag acaaccacgg ccaaggcaca accctccaga aaagcagaac
     7141 catttttctt acacccggca agtttcttca acatttcctt atcttccacg accacgaact
     7201 gccaaggatt actacgtttt gaggccggag ccatcaacgc cgctttcaag atcagttcta
     7261 cctgctcggg tgaaagtagt tgttcggtaa acttacgtgt acttcttcta ttttgtataa
     7321 gtgttgcaaa actctccatt tttttcgttc tttgtactct tttaatatta agattcgcaa
     7381 atataaatat aattttttgc acccatatat acgtatcgtt cttttttctc gttagtattt
     7441 ttataattga acaatagatt atgaagattc gtgcgatagc cgcgctgcta tttatactta
     7501 tttccgtgag tgcctttggc gaaggccgca taaaaatcac tggttatgtc cgtgacgccg
     7561 acggtaaccc tctggaatta gtgaatgtcc gggttaagaa cacgttgatc ggctccatga
     7621 ccaacgagaa gggatattat tccttttcca tatcgccggg ggattctatc tccgttattt
     7681 actcttgtct gggatataat aaagctgaac gtatcattcc ttcggcacaa gccgatatgc
     7741 gcctgaacgt acagatgaac tatacctcat ttgatttagg ggaagtatct gttactgcca
     7801 tccgcaaaca gaccacgacc atggagtccc taaatgcgga caaaatcaag ttattgcccg
     7861 atccctccgg aggtagtata gagagcttgg tcgttacgtt tgccggagta tcgtccaata
     7921 acgagttaag ttcccagtat tccgtacgtg gaggtagtta tgatgaaaat atcgtttatg
     7981 tgaatgggat cgaggtattc cgtccgcttc tgattcgctc gggacaacaa gagggcctta
     8041 gctttatcaa tccggacctg acggaggcgg tcaatttcgc cgccggtggc ttcgaggctc
     8101 gttacggaga caagatgagt tccgtgctgg atattaccta taaaaagcct aagatattcg
     8161 aaggctcggc ttccgcaagc ttgttgggcg cgaatgctta tgtaggcagt tctatcggta
     8221 aatttaccca agtaacgggt ttccgcttta aaagcggtcg gtctattttg ggtaccatgg
     8281 atacagacgc agaatacgac cctaaattta tcgatctgca aacttacatc acgtaccaat
     8341 tggcccctaa atgggaaatc aatttcttgg gaaacctcgc taacaataat tataaattca
     8401 ccccttatag ccgggaaacc tctttcggta cagccgagca tcccaagaac ttcaaagtct
     8461 atttcgacgg aagggaaaga gaccgtttcc aaaccttatt cggtgcgctt acattgaaac
     8521 acaaccccaa tgagaacaca gagttgggac ttcaagcctc cgctttcaaa agcaaggaag
     8581 aagagggata cgatatcgcc ggagaatatt ggctaagcga gaacggagcg gaaaatccgg
     8641 atgacgacgc gtcagccgcc atgtccgtag gccgttatca cgagcacgca cgaaaccgtt
     8701 tgaactccac cgtcatgaat gtcgggcact atgggatggc ccgcctttta aacaatacgt
     8761 tgaaatgggg agccacggta caaatggaga aaatcaatga taagatcagt gaatgggaaa
     8821 aaagggattc ctcaggttat tctttgcccc aaaccggtaa taacgtaagt gtatattcga
     8881 acctcttttc tgataatcag atagaaagca cacgcttttc cgcttatgcg caagacgcgt
     8941 tcaaattcag gaccaagcaa ggtctgttca cgttagtcgc aggggttaga ggtagttatt
     9001 ggacttataa taaggagttc cttttcagtc cccgtgcctc attgggcttt atcccgaact
     9061 tcgaccaaga cttgacgctc cgtttcgcca ccggactgta ttatcaatcg cccttctaca
     9121 aggaattacg tagagtagac aaagataaga acggcaataa tatcacggta ttgaacaaag
     9181 atctaaagtc acaacgctcc atccatttca tattgggagg agattatacg ttccgtgccg
     9241 tagaccggaa tttcaaggtg accgccgaga tgtactataa aaagctggac aatctgaatc
     9301 cctacaccgt agataacgtc aagatccgct attacggcga gaactgcgcc aaaggttacg
     9361 ccatgggact cgatgtcaaa ttcttcggag aattcgtacc gggtaccgac tcatggatca
     9421 gcttctcctt gatgaaagcc cagcaaacca tccgggaaac aacgaccgtt cctatggcca
     9481 atagccaagg ctacaacatc tcactcttct tccaagatta tttcccgggc tataaacgag
     9541 tcaagctaaa tctgaaagga gttctatccg gaggacttcc ccagacaatc ccgggcaaag
     9601 gatacgaagc cggctatttc cgtacgcccg cctacaaacg tgtagatatc ggcctctcct
     9661 atcaattggc aggaggcacg gacgctatca tggacagggg cttcttccgc catttgaaaa
     9721 acatttggct aggtctggat gtatttaaca tattagacat caaaaacgtt agttcctact
     9781 attggataac agatgtatat aatgtccaat acgcagttcc aaactatctg accggacgtc
     9841 aattgaacgt tcgtctgatt gtcgattttt aataaaatgt atctttaaac acatttactg
     9901 ggagataaaa acaaaaaatt atttcctcat tcataaaaag tagtgtacat ttgcacacaa
     9961 tagaaacaaa catttactaa atctttaaat tattattgac atggaactta cacatatcga
    10021 acatttaggt atcgcagtga agagtatcga ggcttgttta ccctattatg aaggcgttct
    10081 tggattaaaa tgctacaata tcgaagtagt agcagaccaa aaagtaaaaa ccgcattttt
    10141 caaggtagga cagactaaga ttgaattact agagccgacc agcgaagata gcacgatcgc
    10201 aaaatttatc gagaaaaaag gtgaaggtat ccaccatatc gcattcgcgg tacctgatgt
    10261 acaggcagct ttgaacgagg ctgaggaaaa aggcgttaaa ttaatcgata aagctccccg
    10321 tggtggcgcg gaaggcttga acatcgcttt ccttcacccg aaatcaactt gcagcgtatt
    10381 gacagagctt tgcatgccgg gcaacaaata attaatccgt tcatttctaa caacaaatca
    10441 aaatacaatg agtaaccagc ttgaaaaagt aaaagagctc atcgcacttc gtgagcaagc
    10501 tcgcttgggt ggaggagaga aaagaatcga atcacagcac aaaaaaggca aatataccgc
    10561 tcgtgagcgt atcgccatgt tgcttgacga aggtagtttc gaggaattcg acatgtttgt
    10621 tcaacaccgt tgtacaaact tcggtatcga gaaaactaaa tatttaggcg atggtatcgt
    10681 aacaggttat ggtacgatcg acggacgttt ggtatatatc ttcgctcaag atttcaccgt
    10741 attcggtgga gccttgtctg aggctttggc tatgaagatc tgtaaagtaa tggatcaagc
    10801 catgaagatg ggcgctcccg ttatcggttt gaacgactcc ggtggagctc gtatccaaga
    10861 aggtgtaaac gccttggcag gatacgcaga gattttccaa cgtaacatct tggcttccgg
    10921 tgttgttccc cagatttccg gtatcttcgg cccttgcgcc ggtggagccg tttattctcc
    10981 ggctttgaca gacttcaaca tcatgacacg tggtaccagc tatatgttct tgactggtcc
    11041 gaaagtcgta aaaaccgtaa caggtgagga tgtaacccaa gagcagttgg gtggagccag
    11101 cgtacacact accaaatcgg gtgtagccca tttcgctgtc gatacagaag aagatggttt
    11161 gcaattgatc cgtaaattgc tcagtttctt acctcagaac aacttagagg aaacgccgtt
    11221 agttgagtgc aaagacccga tcgatcgtct ggatgatgta ttgaacgata tcattcccga
    11281 taacgccaac caatcttacg atatgtatga ggttatcggt acgatcgtcg ataacaacga
    11341 gttcctagag gtccatgcgg actacgctaa gaatatcatc gtaggtttcg ctcgtttcaa
    11401 cggacaatcc gtcggtatcg tagctaacca gccgaaggtt atggcaggat gcttggatag
    11461 caacgcatct cgtaaagcag gtcgcttcgt tcgtttctgc gacgctttca atattccttt
    11521 ggtaacattg gttgacgttc cgggattcct tccgggtaca ggtcaggaat acaacggtgt
    11581 aatccttcat ggcgctaaat tgctttacgc ttatggtgag gctaccgttc ctaagattac
    11641 cgttacattg cgtaagtctt acggtggagc ttattgcgtg atgagttcta aacatttacg
    11701 tggtgatatg aattacgcat ggccgacagc cgagatcgcc gttatgggcc cgagcggtgc
    11761 cgtagaggtt atcttcgcca aggaagtagc agccgctgaa gatccgaaag catgcgcagc
    11821 agagaaagaa gctgaatata agaaagcatt cgctaatcct tataacgcag ctcaatacgg
    11881 ttatatcgac gatgttatcg aaccgcgtaa cactcgtttc cgtattattc gtgctttgca
    11941 gcaattgcag actaagaagt taagcaatcc tgctaagaaa catgataacc tgcctctata
    12001 atccgtaaaa caggagatga atatgataaa taagaaaata ggggtattgc tactgttaat
    12061 ggttctcttc agtatgggag ccaaggcaca gttgactacc tccgttaaat taaatgaagt
    12121 gctagttgtc aatgaagata actttgttga tgactatgga aaacgccatc catggtttga
    12181 gttatttaat aactcagcag gtacggtgga tttacgagga tgcttcttaa cgaacgataa
    12241 aagtaatccc agaaaatata tgatcccgaa gggagatgta cttaccaaag ttcctccccg
    12301 ccagcatctt cttttttggg cagatgatca gccaacaaaa gggacatttc atgtaaactt
    12361 cacattcgat ccaaacaaag ataattatct agccttatat gattcagatg gtacaacttt
    12421 gatcgacgag gtgacaatcc ctgccgggca aaaagcagat gttagttacg gtctggatct
    12481 tgatggagta ggaaattgga gtatccttga caaagtgact cctagcacca ataatctgac
    12541 gttagattcg aatgcgaaac ttgagaactt ccaacggaac gacccatggg gtattggtat
    12601 gaccataaca gccatggcag tcgtattcct tggcttaatc attttgtatc tagtattcaa
    12661 gcagatcggt aacgcagcga tcaaagctag caagcgtaac gctcaaaaag ccgcaggaac
    12721 aggtgctgcc gtatcagcca atatcggtca agaatcaggt gaaatttttg ccgctatcgc
    12781 taccgctctt tatgagatga gcgatgacaa ccacgatatc gagaacacgg tattgactat
    12841 ccacaaggtt caacgcagct attcaccatg gagttctaag ctttattctc tgcgtcagac
    12901 tccaaataaa aagtaatcat cctaaaatcc aattgacgaa tgaaaagttt taaatatacc
    12961 attaacggta acacatataa agtacatatc aactcagttg tagatgatgt ggcagaggta
    13021 gaggtaaacg gaacccctta taacgtaaaa atggagaaac ctgcgaaaaa acaaatggtt
    13081 acattgaaac gtccggctca agctccgacc aatgccagcg gtgaacctgt tatcacccgt
    13141 caagcagctc caagtgtagc cggcgctgtt aaatctccgc tgccaggtgt aattttaagt
    13201 gtagactgta aagtcggcga tacagttaag agaggccaaa agatcttggt attggaagcc
    13261 atgaagatgg aaaacaacat caatgccgat cgtgacggta aaattgtaga aattaaagta
    13321 aacaaaggcg actctgtatt ggaaggtgca gatctcgttg taatcggtta atgatatgca
    13381 agaaagtttc ttacaattcc taggagaaaa tatccaaata tttctctcct atacaggatt
    13441 tgcgaacgcg actccagggc atatcgtgat gctattggta ggtttgctgt tcatattcct
    13501 agcgattaaa tatgaattcg agccaatgct tctgatccct attggtttcg gtatcttgat
    13561 cggaaatatc cctttcaagg atgccggatt acaattaggt atatacgaag agggttctgt
    13621 attgaacatt ttataccaag gagtgaaaca aggttggtat ccccccttga tattcctcgg
    13681 tatcggtgcc atgacagact tctccgcttt gatatccaat cctaagttaa tgctagtcgg
    13741 agctgccgcc caatttggta ttttcggtgc ttatatcatt gcattgcaaa tgggatttga
    13801 cccgagccaa gccggtgcta tcggtattat cggaggagct gatggtccaa ccgcaatctt
    13861 cttgtcatcc aagttagctc ctaacttgat gggtgctatc gctgtatccg catactcata
    13921 tatggcattg gttcctatta tccagccacc gtttatgaga ttgcttacaa cgaagaaaga
    13981 acgtgtgata cgtatgaaac ctccaagagc cgtttcacag acggagaaaa tcgttttccc
    14041 gatcgttggc ttgctattga cagccttctt ggtaccgtct ggtttgccat tgttaggaat
    14101 gttgttcttc ggtaacttga tcaaggaaag tggtgttact cgccgtttgg cagagacagc
    14161 ccgcggcccg ctgatcgatg ttattacgat cttgttaggc atcacggtag gtgcttctac
    14221 acaagctacc cagttcttaa cattgaactc tatcaagatt ttcggtttgg gtgcgttgtc
    14281 attcgttatc gctacttgtg ccggtgtatt gttcgttaag ttctttaacc tgttcttgaa
    14341 agaaggcaac aagatcaatc cgttgatcgg taactccggt gtatccgccg tacctgacgc
    14401 tgcccgtatt tcccagaacg taggtttgga atacgatcca agcaactact tgttgatgca
    14461 cgctatgggt ccgaacgtag caggtgtaat cggttccgct gtagctgccg gtatcttgct
    14521 aggattcctt ggttaataaa acaactatct atattaaaaa aggcgaggtc cgaaaggatc
    14581 ccgccttttt atgttattgt tctcagttag cttgctctat aggaaccgga ctaatctccg
    14641 tactcgtatc ctccaccaac gttgtcccga ggaacaacca gatcatcaaa aggattatag
    14701 cgacaaccac accaaatacc aatagcgtat tcacactttt ctttctcatg tctttaactg
    14761 atttattcat tttagaataa acagccggaa catgaatttg gttgtgtact cttactctta
    14821 tttgtttttc cctaacgcct cgttcagcac tttgttctta gcgatcgttg cttggaattc
    14881 tttcaaatag aaaggctcaa aataagccac attctcaaaa cggccatcat catatgcttt
    14941 ctgcgacaag gatgccatat ttacagctaa tggatagata ccatctataa aacaggcgtt
    15001 cggagaagtg attaccgtct cacatttagc ggcaccgtct ccaaagaaac aaaccttacc
    15061 gttctctaaa aaagaagcat acgaatcagc atctacgata tcagcagtcg tggcacgtat
    15121 cgtgttgaga tgggaatcat aaatcgaaga gtagacttcc atacgacggg catccaacat
    15181 agcgcaatac aagcaatcgg cctcctcctt atttttccga atagcggcag acgctaaaat
    15241 atccagcgta tgaataccga tcaaaggaat accataccca aagcataatc ctttagccac
    15301 agacaccccg atgcgtaacc ccgtataaga tccgggtccg ctacttaccg ccacagcatc
    15361 cagttttatc cctttcgact tcgcagcttc taatgcctct tccatataaa cgcccaataa
    15421 cgccgcatga gacggcccct cgaaggaagc cttctcaaag accacctcct ccccttccga
    15481 cagggctact gaacatacgg aagtggatgt ctcgatattt aagatcaatg acataataat
    15541 taactattaa caattgataa ttgaacgaac aaacaatctc aatccttcaa tctgattagg
    15601 ctgcgaaggt atacaaaaat tcattatgct atcaaggcag ccctatgaga aacatctatt
    15661 tatgagaaaa taaacatcaa atctaaaagg aaaccactat ctttgcgcaa acttttgaga
    15721 aaaatgatac aatcaatgac tgggttcggt aaggttactg ccgagctccc ttcaaaaaaa
    15781 gtaaccgtag agataaaggc tttaaacagt aagcaattgg atttgtccac ccgtatccct
    15841 tccatataca aggataagga aatggagctt cggagcctgt tacttcaatc tttggagcgg
    15901 ggaaaagttg agttcaatat ctttatagaa tatataggca aagatactcc tacacagatc
    15961 aatcttgccg ccgtagagaa ttattacaac caaatcaagg agatcgcaga gaaactgaat
    16021 atcagcgttc cgaacgattg gttccagacc ttgctccgga tgccggacgc aatcaagtct
    16081 gagaccgtag aaccggacga atccgaatgg gaggtggttt tagaaacggt aaaggacgct
    16141 atcaagcacc tgtgtgattt ccgtatccaa gaaggagcca tgcttcaaaa gcttttcgag
    16201 caaaagatag ccaatatcgc cactctgttg aaagaagtgg agaaatacga gggggaacgt
    16261 atcgagaaga tcaaggctcg tatcatggat aacctgcaaa agatagccga gaaggactac
    16321 gacaagaatc gtttcgagca ggagatgatc tattacatag agaagctgga tgtcaacgag
    16381 gaaaagaacc gtctggacaa ccacttgaaa tattttatct caaccatgga atccggtcac
    16441 ggccaaggca agaagctcgg ttttatcgct caggaaatgg ggcgtgagat caatacgctc
    16501 ggatcaaaga gcaaccacgc cgagatgcag aagatcgtgg tccagatgaa agacgagttg
    16561 gaacaaatca aggaacaggt actaaacgta ttataataag attaacgaga atggctggca
    16621 aattaattat cttctccgca ccctcgggtt ccggaaaatc aaccattatt aattatcttt
    16681 tgaaacaaga tttacacctt cgtttctcca tctcggctac cagccgggct ccgcggggaa
    16741 ccgagaagaa tggtgtggaa tattatttcc ttacgccgga agagttccgc agtcgtatcg
    16801 ctaatggaga cttcttggaa tatgaggagg tgtataccga taaatattac ggtacgttaa
    16861 aaagcgcggt agagcgtatc ttgaatgaag gggnnnnnnn nnntggtagg cggatgcaat
    16921 atcaagaaat tctatggaga ccgtgccctg tctgtcttta tccaacctcc ttgcatcgat
    16981 gacctacgga agcgattgga aggacgggga acagacagcc cggaagttat cgaaagccgt
    17041 atcgccaagg ctgagtatga attagggttc acgggacagt ttgataaggt tgtcgtaaac
    17101 gatgatctgg agactgccca aaaagacgcg ttgaagatca ttcgtgagtt cttaaacaaa
    17161 tagtctatgc ctaatatatt caagaatacc cgttttatga tggggctttc tatcgtttgt
    17221 gggatagcga gcctcgtatt aggtggtatc agcctgtatt ataaggagta tatcatcggg
    17281 ggtgccctga tatttaatat attcatttgt tttatcaact ataagggttg gcaaaagaag
    17341 gggtaagtat aaatcggatg agactcaaga tcggcatcta cagtggatcg ttcaatccca
    17401 ttcacatagg ccatctcgcc ttggcgaact ggctatgtga gttcgaggga ctgaatgagg
    17461 tgtggttcgt ggtcacgcct cataatccgc tgaagaaaaa ggatgacttg ctagatgact
    17521 cacttcggtt ggaaatggcc caagccgcca ttgacggata tccgaaattc aaggtctgcg
    17581 atattgagtt ccacctgccg aaaccttctt attccattga taccttgcga gccttatcca
    17641 gcaactatcc ggatagggac ttttatttta tcatgggagc cgataactgg ctgctttttc
    17701 cccgatggaa agaatatgaa aaaatactcc aaaactacaa actgctgatt tatccccgcc
    17761 taggattcga tatctcgatc ccaaccattt atccgaacgt gaaaaaggta gacgctccct
    17821 tgatggaaat ctcctccaca tttatccgta acgcttacca aaccggcaag gatatccgtt
    17881 tcttcctgcc ggaaggagtg cggccttatt tcgggtcagt agcaaatcag tgacatacct
    17941 gcgatagaag atatacttac ttgggttatg aagtatatat cctatgccac ttgaagtata
    18001 tattcttcga gaagggaagt tataccgtga ttatttacag ctttgccatc ttagggcaat
    18061 ctgccaaaat tcccattaaa acatgtttta cagcacagcc gttaaagatg atccccgtaa
    18121 catcaaaaca ggctcacccg ataatctttt tggagtatcc aaatatataa tttgagcctt
    18181 gtcaagtgaa taactaacgg ttacaccgag gattactgaa tggtttcccc ggtgtgatat
    18241 tggcattgtt gaacattaag caaagatatt tatgcgaata gacttgacaa gatctaagac
    18301 atacgaggta gcttatccat acgatgggaa tgctttggac acttcaaata tattgaggga
    18361 acattactgg ccacatagag acattgactt cctaaaaaaa acaccaaaga aaaatgaact
    18421 ctttgtatat ggtggaagga gttattgggg cagtcggagg agcgattttt gtccaaacga
    18481 acaaatatct gcaagcgggt atggaaaatg aggatttcta tggctggggc ttggaggacg
    18541 gagaaagaca ttaccgttgg ttgagttttg gctaccggat tgacggagtg agggctgttt
    18601 attccatttg tctcatcccc gggatcaaaa cgggatgtaa agataaaatt attgggtctt
    18661 aagttcatta gcctacaaac ctaagatact tcaccaagga tcctaagata ctttaccgat
    18721 gaacctaaga tactttatcc atgaacaaac aagatcggtg acctcaacct tttaccacat
    18781 aagtcagcat aaatcagaaa tattttgtac ttttgcgccg tattatacaa aataatagca
    18841 taatgaatct attagaactg agtgaacagg aaataataag acgtaatagc atggagcagt
    18901 tgcgtcagat ggggatagag ccttatcccg cagctgagta tgtaacgaac gcattttcca
    18961 aagaaataaa agagacattc aaagacgacg ctgagccacg cccggtaagt atcgccggcc
    19021 gtatcatgag ccgtcgtatc atgggtaagg cttccttcat ggaattgcag gattccgagg
    19081 gcagaataca ggtctatatc tcccgtgacg atatttgtcc ggatgagaat aaggacacct
    19141 acaatgtcgt tttcaagaaa ttactggata tcggtgattt cgtcgggatc aagggattcg
    19201 ttttccgtac tcagatggga gaaatttccg ttcatgctca agaattgaca gttttgtcta
    19261 aatcacttcg tccgctaccg gtcgttaaat ataaggacgg tgtcgcttat gacggtttta
    19321 atgacccgga gcttcgctac cgtcaacgtt acgtggattt ggtagtaaac gatggcgtaa
    19381 aagatatttt catgaaacgt gcggctatca tcaagaccat gcgtaccgct ttggatgagg
    19441 ccggatatac ggaggtagag actccgatcc tgcaatctat cgccggagga gctagcgcac
    19501 gtccgttcac gacacatcat aactccttgg acatcgattt atatttacgt atcgctaccg
    19561 agttgtattt gaaacgattg atcgtcggtg gattcgaggg tgtatacgag atcggtaaga
    19621 atttccgtaa cgagggtatg gaccgtacgc acaacccgga gttcacttgt atggaacttt
    19681 atgtccaata caaagactat aactggatga tgagcttcac tgagaagctg ttggagcgta
    19741 tctgtatcgc cgtgaacggt acgagcgaga gcacgatcga cggtaagaca atcagcttca
    19801 aggctccttt ccgccgtttg ccgatcttag aggcgatcaa ggaaaagacg ggttacgact
    19861 tggaaggtaa gagcgaggac gagatccgta cgatctgcaa ggaattgaag atggagatcg
    19921 acgatacgat gggtaaaggt aaattgatcg acgagatctt cggggagttc tgcgagggta
    19981 cgtttatcca gccgaccttc atcatcgact atccggttga gatgagcccg ctgactaaga
    20041 tgcaccgtag caaaccggga ttgaccgaac gcttcgagtt gatggtaaac gggaaggaat
    20101 tggcgaacgc ttatagcgag ctaaacgatc cgatcgacca agaagaacgt ttcaaggagc
    20161 aattacgctt gagcgagaaa ggggacgacg aggcgatgtt catcgatcaa gatttcttac
    20221 gcgcccttca attcggtatg cctcctacgt cgggtatcgg tatcggtatc gaccgtctgg
    20281 ttatgttgat gaccggacag acaacgatcc aagaggtatt gcttttcccg caaatgcgtc
    20341 cggagaaaac cgcaaagaaa gataacgccg acaaatacgt agccttgggt atttccgagg
    20401 agtggattcc cgctttgcag aaagccggct acctaacggt tgacacgctg aaagaagcga
    20461 acgccaacaa attaagacaa gatctttgtg agcttaataa aaaatataag ttagaactgc
    20521 aaaatcctac ggtccaagaa gtagaggctt ggatagccaa tgtaggagaa taaaagcgtg
    20581 atacgatgga tttgcccgga aaaatcgcga taatgggagg tggtagctgg gctaccgcct
    20641 tagccaagat cgtactttca actcaagata gtatcaactg gtacatgcgt aggcccgatc
    20701 gtatcgagga gttcaagcag ttgggacaca acccgtgtta cctcaccgcc gtgaaattcg
    20761 acacgaacaa gataaacttc tattccaata tcaaccaagc gatcaaggac tcggatacct
    20821 tgatcttcgc tacgccttcc cctttcttga aacaacattt gaagaaggtg aagacctctt
    20881 tgaaagataa gtttatcatc tcggcgatca agggtatcgt accggatgag aatatgttga
    20941 ttacggatta cttcgcggag tattacaagg ttccgacaga aaatatagca gttatcggtg
    21001 gtccctgtca tgcggaagag atcgctctgg agcggctctc gtacattacg ttggcttgtt
    21061 ccgacatcga taaggtccgt acgatatccc ccgttttcaa gaatcaatac ttaaagaatt
    21121 ccttctgtaa ggatgtgacc ggtatcgaat acgccgccgt actgaagaac gtgtacgcta
    21181 tcgccgccgg tatttgccat gggatgaaat atggcgataa cttccaagcc gtatttatct
    21241 cgaacgctat tgaggagatg cgtaatttcg tggacgccgt acacgggctg gagcgggata
    21301 tcaccgactc cgtctacctt ggcgatttgc tggttaccgc ttattcccgg ttcagccgta
    21361 accgtacttt cggaaccatg atcggtaaag gatattccgt gaagacagcg cagctggaga
    21421 tggaaatgat cgccgaggga tattatggaa ccaagtgtat gcgtgagatc aatgagaaat
    21481 ataaagtgaa catgccgata ctggacgctg tttatgatat attgtacgag aagaaatcgc
    21541 caacaacggt cattcgtcaa ttaacggaaa cgtttaaata aaatagcata tgaaaaacat
    21601 cagtttaaac atcgacaagg ctctgggcac tgtctccaag gaacaggttt acgctcaaga
    21661 ggccaaggca atggaatgta ttgccacatt acataacggt aacggagcag gtaacgactt
    21721 tttgggttgg ttgcatctcc cctcttctat cacggacaca gagttggccg acatcgagaa
    21781 tacggcgaac gtgcttcgtt ctaaatgtga agtggtcgta gccattggta tcggtggtag
    21841 ctatttgggt accaaagcgg tagtagaagc gttaaacaac agcttcgact ggttgcaaaa
    21901 cgaccgtaaa aacccggtta tgttatacgc cggacacaat atcggagagg attatcttta
    21961 tgaattaagc gaagttttga aaggtaagca attcggtatt atcaatatct ccaagtctgg
    22021 tacgactaca gagccggctt tggctttccg tatcttgaag aaacaattgg aagatgctgt
    22081 tggcaaggaa gaggctaaac atcgtatcgt agctatcacg gacgctaaga gaggcgcttt
    22141 acgtaccttg gcggatcaag aaggttacaa gactttcgtc atccctgata acgtaggtgg
    22201 acgtttctct gttttaactc cggtcggttt gcttccgatc gccgtggcag gtatcagcat
    22261 ccgcgacttg gttgctggag ctgtttccat ggaaaaagct acagacgcga gcgttccttt
    22321 cgctgataat atggccgcta tctatgccgc tactcgtaac gagttgtata agagcggtaa
    22381 aaagattgag atcttggcta acttccatcc gaaattgcat tatatcgcag aatggtggaa
    22441 acaactttat ggagagagcg aaggtaaaga cggcaaaggt attttccccg catctgtaga
    22501 tttgacaacc gatttgcatt ccatgggtca atggattcaa gacggtgagc gtacgatttt
    22561 cgaaacggtt atctccgtgg aagctacaga tcatagcgta ttggttccta cagacgaggc
    22621 tgatttggat ggattgaact tcttggcagg caagcatgta gacgaggtaa acaagatggc
    22681 tgagttaggt actcagttag ctcacgtaga tggtggcgtt cctaatatca aggtaactat
    22741 gccggaagta agtgcgttct atattggtca gttgttctat ttcttcgaga aagcttgtgg
    22801 catcagtggt tatatgttgg gcgttaaccc attcaatcaa ccgggtgtcg aggcttataa
    22861 gaagaatatg ttcgccctgt tgaataagcc gggatacgag aaagaaagcg aagctatcaa
    22921 agcacgttta taatacgatt taccccataa aaaaacggtt ttctcatcac gaggaaaccg
    22981 ttttttcgtt tgaatagttt ttattactca tttaattctt taagtaaatc gctcccggcc
    23041 ttgaatttga ccgagacacg tggagtaatc attacttcct cccctgtttt cggattacgt
    23101 gccaatcgct cggattgttg ccaaggtaca aaagatccaa atcctttcat ggaaatagat
    23161 tctccttccc gtattccttt cgccacaaca gtcggtaacg cattcactac ggttctaaca
    23221 acatttttcg gcaatcctgt ttcttccaca agagattgta ctaattctcc tctattcata
    23281 ctagataata aatataccat tcttcaccag aaaagagtcc ggtgagaact tagttgttta
    23341 atcattgcaa atatatgaat atttggggaa tatcaaaata acatatatta aaaatcaatg
    23401 catacagaaa tattatatac ctaaatgtag gtataattga acccctttca gatagacaag
    23461 tgagactttg gtagaaatat aattaataag aaatagtata cagtattatg atatcactta
    23521 ttcatagcaa gttatagcct ttgaaaattc gttattaatg cgtttactag agttctcacc
    23581 gaactacgtc ataatttatt gattaattat ctcaacgaaa taaatttata tcccttattt
    23641 ttcaatacat ccatcaactc atccagataa ttatagaatt tatcaatccg gttagggtgt
    23701 acatgtaggt ggatcaaaag taagcaccca tttaaaccat ttttgtttca taaaatgaaa
    23761 ttccattata tatcatattt atttaatttc aagaagcttt cctcccattt ctgttaattc
    23821 cgatttatta cgtacctttg tattggtttt taagaaggta ataacatgat tcaagaagcg
    23881 attatccgat atctgcgtaa acacaggcag gaatcccttt ctcccaaagc tgttcttttc
    23941 gatatggatg gtgtattata tgactctatg cgttttcatg cacgggcatg gcatgaggta
    24001 gcgaccctcc atcagctaac ttctcggccg gaagactttt atatgttcga aggacgtact
    24061 ggggaaagca cgatcaacga gctataccaa cgcactttcc aacgagacgc taccgccgag
    24121 gagaagcaaa cgatctataa agagaaagcg gatctattca atacctataa tgacggtgcc
    24181 cccatgatcg gcgccgcaga ggttctaaaa gaagtggaag catccggact gcaacgattg
    24241 gttgtcaccg gttccggcca acatagcttg atcgataagc taaaccatac ctatccggga
    24301 catttcaacc gagagaaaat ggttacggct ttcgacgtga aatatggcaa gccacacccc
    24361 gaaccttatt taatgggact tcaaaaagcg catgcgaagc ctaatgaaac ttttgtggta
    24421 gagaacgctc ccatgggagt agaagctgcc gtggcagcca atatctttac gatagccgta
    24481 aacaccggac ctctccccga tcaagtttta ttagatgccg gagcggattt actata
//
