LOCUS       gnlProkkaFNCPDCCN_26   10879 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FNCPDCCN_26.
ACCESSION   gnlProkkaFNCPDCCN_26
VERSION     gnlProkkaFNCPDCCN_26
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 05:54:59
            Original ID  :: gnl|Prokka|FNCPDCCN_26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10879
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..339
                     /locus_tag="ctg26_1"
                     /transl_table=11
                     /translation="MIPKNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGYSDNARK
                     SKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIA
                     SIANLIKK"
     protocluster    1..10879
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1565:5879]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1566..5879
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10879
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10879
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             354..1502
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1566..2285
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.9e-16, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2306..3607
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1e-12, bitscore:
                     40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3624..4748
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.7e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4758..5879
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg26_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.1e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4848..5855
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg26_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg26_6_Aminotran_5.1"
                     /locus_tag="ctg26_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5876..6019
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6222..7706
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.2e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7660..8919
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             8928..9674
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKKF"
     CDS             9678..10718
                     /locus_tag="ctg26_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 ttcataccta agaatactaa tactgtaact atcaatggtg ctgtcatggt tccgaatacg
       61 gtttcttata tgaagggcaa gaatgtggat tattacctga atcaggccgg tggttattct
      121 gataatgcaa ggaagagtaa gaaattcatt gtttacatga atggtcaggt gacgaaggtt
      181 aagggtagtg gtaagaaaca gattgagccg gggtgtgaga ttattgtgcc tggtaaggct
      241 aagaagaaag ggaacatagc taatatttta ggttatgcta cttccttcag ttctttggga
      301 atgatgattg cttctattgc taatcttata aagaaataat agaatttact tttatgtcag
      361 aacaacgaca ggataaaaac ttgctctctg aaccacacaa gacagaaagt gatgagatag
      421 aaattgattt ggtcgatatc tttcgcaaga ttattgctat tcgtaaaaaa ttatacaaag
      481 ccgttggaat tggttttatt attggaataa ttgtagcggt aagtatccct aaacagtata
      541 cagtaaaggt taccctttct cctgaaatgg gtaatgcgaa ggggagtaat ggtttagccg
      601 gacttgctgc ctcgttttta ggagatgggg ctctaatagg ggaaagcaca gatgccttga
      661 acgcttctct ttcagcagat attgtttctt caactccttt tttattggaa cttttagaaa
      721 tggaagtctc cgtttctaaa aaggatgata aaatgacttt ggggtcttat ctcgatgaag
      781 agtcatctcc ttggtgggat tatcttatag gttttccggg catagtaata ggaggagtta
      841 aatcattatt cggagaagat acggttcctg ccagtggagg gcggcaagga actatcgaat
      901 tgacgaaaga agtaaatgag aagattaatt ttcttaaaaa gaagattagt gcatccattg
      961 ataagaaaac cgccataacg agcattacgg tcaccttaca aaatccgcag atcactgcgg
     1021 ttatagcaga ttctgtcgtt cataaattac aggaatatat tattgggtat cgaacttcaa
     1081 aagtaaaaga agactgtgcg tatttggaac ggttgtttaa agaacgtcag caggaatatt
     1141 atgctgctca aagaaaatat gcggattatg tagacgccca tgataatgtg gttcttcaaa
     1201 gtgtacgtgc tgagcaggag cgtttacaga acgacatgag tttggcttat cagatatata
     1261 gtcaggttgc taatcagttg caggtatcca gagccaaagt acaggaggaa aagccagtct
     1321 ttgcagtagt tgagcctgcc gttgtacctt tgaaaccttc aggtatggga ctcaaaattt
     1381 atattttatt atttgtgttc ctgtccgtat ctggtactct cgtgtgggtg ttttttggca
     1441 aaagtctgct ggctagcttg agaaaagaac tgaaaaataa ggagatagaa caggataaat
     1501 gatgctaaaa cgtcgtttac aacattctta catcaattaa attcacttac tatattatta
     1561 aacgaatgat acgtacagct atgataatgg ctgcgggcat gggaacccgt tttggccaat
     1621 atacagaatt gatacctaaa gggttcgtca aagtgggagg tattccaatg atagttcgtt
     1681 ctattgatac tttgttatca tgtggcattg agcgaattgt aatcggtaca ggatataaac
     1741 aagaagttta tgaagaattg aagacagact atcctatgct tgaaacctgt tttagtcctc
     1801 gttatgctga aacaaatagt atgtatactt tatataatac gcgggagatt ctgggcaatg
     1861 atgatttttt attgttagag tcagatttga tttttgagaa acaagcaata atgagcttat
     1921 tggagtgtcc tgcggcagat gcaatgctaa tagctccagt gacaaagttt caagatcagt
     1981 attatgtgga acatgatgat aattttcgcc tttcttcatg ttctgtcaat aagaataaac
     2041 taaacgctaa aggcgaattg gtcggcatcc ataaactatc cggttccttt tacaaaataa
     2101 tgtgtgctga ttatgcgagt attgttgatg aacaacccaa tttgggatat gagtatgaat
     2161 tactacgaat atcttgttct caatctcctg tttatgtgca taaagtagaa gggctgaaat
     2221 ggtatgaaat cgatgacata tcagatttgg aatatgcaga gaaatatatt gttccgtatt
     2281 gttaattaaa ataatatatc aaattatgag taagacagtt tatattggga tgactgcgga
     2341 tattatgcat ccaggactta tccgcattat taatgaggct actaaatacg gtgatgttat
     2401 aattggtctt cttacagata aagctattgc ggagcataaa cgccttcctt atctgaccta
     2461 tgaacaacga aaagaggtag ttcagaatat taaaggcgta tgtaaagttg ttcctcaaga
     2521 agaatggagc tatgttgaga atctcaaacg cattaaacct gactatataa ttcatggtga
     2581 cgactggaaa accgggcctt tacgtgaaga acgtgtgcgc gtatttgaag tgatgaatga
     2641 acagggagga aaggttatcg aaattccata tactttggga attaattcat cttctttgga
     2701 taaagatatt aaggctatag gtacaacccc tgatgtacgt ttaaaatcac ttcgtcgttt
     2761 gataaatgcc aaacccgtag ttcgtatttt ggaagctcat gatggactat gtggcttgat
     2821 aattgaaaat caggaaatat taaaagggga taagagggaa gtatttgacg gaatgtggtc
     2881 tagtagcctt acggattcaa ccagtaaagg taaacctgat attgaggcgg ttgatttaac
     2941 tacccgattg caagatttga ataatattct ggagtgtact actaaaccta ttatttttga
     3001 tggagataca ggtggtaaaa ttgaacattt cgtatttaca gtacgcactt tagaacgtca
     3061 tggaatttca gctataataa ttgaagataa agttggatta aaaaagaatt cattgtttgg
     3121 tacagatgtt attcaaactc aagatacaat cgaaggtttc tgtaataaga tcaaagcagg
     3181 aaaggcatct cagattactg atgattttat gattatcgct cgtattgaga gccttatagc
     3241 gggaaagccg gtaagtgatg ctttagagag agcttttgca tatgtccaag cgggagcgga
     3301 cggtattatg atacatagca aaaataagtc gggtgaagat ataaaagaat tttgtttggc
     3361 gtttcgaaaa cagtatgctc atgtacctat cgtggttgtg cctactacat atgatcatat
     3421 ttatgagtct gaattgtgtg attggggtgt gaatataatt atttatgcta atcatatgct
     3481 tcgtgccgct tatcctgcta tgatgaatgt cgcaaagata atattagaga atgaacgtgc
     3541 tttagaggtg cgcgaactgt gtatgcccat aaaagaaata ttggaactga ttccaggtac
     3601 taaataaaaa gaggaatatc attatgttaa gcgtagaaaa agtttatgaa acgtttctga
     3661 gtcatgacgt tgattttttt acaggagttc cagactcatt actaaaaaat atttgtgcct
     3721 atatcacaga ccatacttca cgtgagaaac atatcatagc tgctaatgaa ggtgcggctg
     3781 taggaattgc ttcaggttat tatatggcat caggtaaggt tcctgtggtt tatatgcaaa
     3841 attccggctt gggtaatact gttaatcctc tgctgtctct tgcagatgaa caagtataca
     3901 gttttccaat gcttttgatg attggctggc gtggtgaacc gggaacaaaa gatgaacctc
     3961 agcataaaaa acagggtgag gtaactttag atttgttgaa agcaatgcgg attccttata
     4021 taattcttga ttcaaatgag aatgatgcat ttattcagct ccatgatatc atacaatcag
     4081 caaaaactaa gaatattcct catgcaataa ttattcggaa agatgttttt ggcaaatata
     4141 aacttcaaaa agagttcgga tgtaattatc ctttatctcg tgaggatgct ttgcaaatag
     4201 ttgtggatta tctgcctgaa aattcagtgg tcgtttctac tactggcaag ctttctcgtg
     4261 agttatttga atatcgagaa atgaaagagc aaggtcatga acatgatttt ctcacggtag
     4321 gctctatggg acatagttca tcaatctctt tgggtattgc tatagcaaag caagatagac
     4381 ctgtttattg cttggatggt gatggagcat ttattatgca tttaggggca attagtaaca
     4441 ttggcgattt atctcctaaa aactattatc atattttgtt taacaatggt gctcacgagt
     4501 ctgtaggagg acagcctact ttaggattta gtttagatat tccggctatt gtccggggga
     4561 gcggatataa gcatacttat actgtttgta caaaagttga aattgaagaa gcaatgaagc
     4621 agcttccaaa gttatgtggt cctgttttgt tggaaataaa ggttaaaata gattctcggg
     4681 agaatttggg acgtcccacg actactccta tagagaataa ggagcatttt atggattttt
     4741 taaaataaat atattcgatg aaaatagaaa gaaaaatatt attaaatcct gggcctgcca
     4801 ctactactga cagtgtaaaa atggcacaag ttgttccgga tatttgtcct cgcgagaaag
     4861 aattcgcagg tatgatgaaa caacttcggg acgatttggt cagagttgct catgggaatt
     4921 tggaaaaaca taccgctgta ttattttgtg gctcaggaac catcaatatt gatatatgtc
     4981 taaattctct tcttcctgaa gacaaaaggg tgcttatagt gaataatggg gcatatagta
     5041 cccgtgctgt agaagtgtgt caatattatg gtttgcctca tattaatttg gaattttccg
     5101 tttacgaacg tcctgattta tcggtggtgg aaaatgtgtt gcaagaaaat cctgatatag
     5161 ctatggttta tactactcat cacgagacgg gtacaggaat tctgaaccct attcgcgaga
     5221 tgggcgctat agctcataaa tatcaggcta aatttgtcgt cgatactact tcttctttgg
     5281 gcatgattcc ttttgatata gagaaagata atgtggattt ttgtatggca tctgctcaaa
     5341 aaggacttca agcgatgaca ggtctttctt ttattatagg caatgaggaa cagattaagt
     5401 tttcaaaaaa atatcccaag cgttcttact attgtaatct ttatttgcag tatgagaatt
     5461 ttgagagaac aggtgaaatg cattttactc caccggtaca aactatttac gccactcgtc
     5521 aggcattaaa tgaatatttt gaagtgggtg aagaagctaa gtttgcccgt cacaaaagag
     5581 tttttgaggc tattcattca ggtataaatg aaattggtct taaaagtgta ataaagcgtg
     5641 aatggcagtc aggactggtt gtctcagttc aatacccaga agatcccaac tgggattttg
     5701 agaaaataca tgattattgt tatgagcgtg gatttacgat ttatccaggt aagatatcaa
     5761 ctgaggatac ttttagaatc tgtgctttag gagagataga agtagatgat attgagaact
     5821 tctttaaagt actaaaagct gcattaaatc attataacgt cacattaccg atgtcatgat
     5881 tgcagaaata ttattgaaga ttcgtcattt ttatttttcc cttcgtggta tacacttcca
     5941 tccggaaagt gttatttctg gagtgcctat tcgtagcttt cgcttagtag gcaaatatgg
     6001 caatattaat ttgaggtgat gcattaggag ttctttattc ttataaaaag gcatcggtag
     6061 ttataggaga taatgtttgt gtagggtaat ttgcttttag tgggagagac catattagaa
     6121 ttgcggtaag gggcgaagaa gataataacc aattagtgag aatattggaa aaatataatt
     6181 gatatcggta aatgtagttg tttttatact gtatttaagt aatggaaaat ctaaagcaga
     6241 aaactgtatc aggaataatg tggagcgcta tagaacgttt ctctttacaa ggagtacagt
     6301 ttataattca aataatatta gctcgtttgt tactaccatc ggattatggt atgatcggga
     6361 tgttagctat ttttcttcaa gtcgctcaag tatttataga tagcggtttt acaaatgctt
     6421 taatccagaa aaaagataga actgaagagg attttgccac tgtcttttat tttaatattc
     6481 ttgtcgcagt attattctat ggtatattgt ttttttcggc ttctttgatt gcagactttt
     6541 ataatatgcc gactttagtt cttgtaattc gttttatagc attgtcgttg ataataaatg
     6601 ctttatcggc tattcacaga acgaaattaa ttatttctgt aaactttaaa actcaatcta
     6661 aaatttcatt aggtgcagct tttatatcag gcgtgattgg aatatggatg gcttatgtcg
     6721 gttgcggggt ttgggcttta gtttggcaaa ctctcttaaa tagtataatt ttgacaattt
     6781 tgttttactg tttagttcat tggaaacctt tacatacttt ctccaaaagt tcttttgaaa
     6841 gattattcaa tttcggatct aaattattga tctcaagtct tatcaataca gtatatcgta
     6901 atctgtatac cattgtaata ggaaaaaagt tttctgttgt agagcttggt tactatacaa
     6961 gagcagaaca atttgctatt tttccttcca ataatttaaa tgctttagtt tctagagtag
     7021 cgtatcctat tttaagttcc attcaagatg atgataaatg tttaacaaac gcatatcgaa
     7081 attatatcag attatcctca tatataattt ttcctttaat ggtaggttta cttgttttgg
     7141 ctaatcctat tattagtcta ttgttaacag ataaatggtc tggggttgtt attcttttac
     7201 agatattatg tttggattgg atgtttgatc atttgagcca aattaatttg aatttattat
     7261 gggttaaagg aagatctgat ctgtcgttac gtcttgaaat aataaaaaag acgattgcta
     7321 tattcattct ttttgtgtca attccatttg ggcttgaggt gatgtgttgg ggtagagtta
     7381 tttactctct gatagcgaca tatttgaata catattatac taattctctt attgatttga
     7441 ccttaaagtt gcaagttaaa gatgtatttc caagtttaat actctctttc ataatggggg
     7501 ggatcgtttt tatatgtatt tctttctttg aaactgatat agtaaaaatt gtgattggat
     7561 gtattactgg gatgtccttc tatattttac tttcttttct ttttaagcta gattcttttt
     7621 tttgtatttt aacattgatc attaaaacta aaaacataga tgaaaatatt aaaaaagatt
     7681 tttcaagtaa tagtaaagat aattaaccat tgtgtgccag ttgatagtag atcattgtat
     7741 tttattcctc atcctaattg tagaacagat aaatatgata ttataaatta ttcgtcagat
     7801 aatgttctcg ttctgttaaa ttatttgcta aaaaaagata gtgctgaata ttataaaata
     7861 tatgttgaaa tttatgattc ttctcgtatt tcagaatatc aagaatatat ttatggcata
     7921 aatcctaata ttaggtgtac ttttttatgt gcatgtgttg gacgtttttt ctttaataaa
     7981 gtatctttta aggatatgtt gtatgccttt ttttgttttt gtagagcaag taaatgtttt
     8041 acagctactt tttattatga tttttcattt aaaaaacgct ctcaacagat tatttgtttg
     8101 gggtattata ctccattcaa agatgattat catatgggag atcattctta tgataaattt
     8161 cgtaatacaa catgtaactc atttgattac tctattgcta cttcttgttt aagtgctaga
     8221 ataatttcaa tagattgtgg aatctcatat gataaattca aagtcttagg atttcccaga
     8281 aatgatttgt tgatatcgaa aaataattgc aatgttatta aaagagaaat ttcgaaattt
     8341 gcgggatatg atgtaactaa atatatagtt tatactccaa cttttcgtga ttatgagact
     8401 gttactgaag gtaatttgcg ttcaatactc ggatatgttg attgtgattt gttgaagtta
     8461 tcgaaaatac tattgaagtt taatgcggct ttaattctta aattacatcc tttgcagaat
     8521 aaaacagtct taaaaaaaga tttacccaaa ggtatacttg tttttgaaca aacatataaa
     8581 tatggattgt atgatctttt gtcattttca gatggaatga ttactgatta tacttctacc
     8641 tattttgatt ttttattggt aaataagcca gtcatattta atttctacga tattgaagaa
     8701 tatcgtagag taagaggttt ctcatttgag ccaatagaat ttttttgtgc aggtgatatt
     8761 gtttacaatt ataatgaatt gatagatgct gtgatgggac ttctggctgg gaaagatatt
     8821 catgctgaac atcgacgtca tatttcttta ttgatgaatc aatttcaaga tgataattca
     8881 acaaagagaa tatgtgacat atttttaaat gaaatataat aaataaaatg aattatgcat
     8941 ttgtggtgca ggcacgttta ggttctacac gtttgcctgg aaaaatattg aaacctttct
     9001 atggtaatca atcgattctt gacttaatgg ttcataagct ttctgctata tcgaatattc
     9061 cagtaattat tgctacaaca aattctgtta tcaatgaacc tattgaaaag aaggcacttg
     9121 cattaggggt aaagtgcttc agaggtgagg agaatgatgt tttaaaacga ttcattgatg
     9181 ttgctgaata ttttgatata cagggtatat tccgaatatg ttctgataat ccatttttag
     9241 atgtacatgc ggcaaggcaa ttggtcgaaa tagcaatgaa atcttgtaac gattatataa
     9301 gttttgatat tgatggtact ccatcaatta aaactcattt cggtttttgg ggagaatttg
     9361 taacgcttga tgcgctgaag cgagttatag gatttactga tgatttattg tatcgtgaac
     9421 atgttactaa ttatatatat agtcatcctg aactttttaa tattcaatgg atttcaggat
     9481 ctccagtcgt gtcaaaacat cataatattc gactcacgat tgatacgtta gaagattttt
     9541 ctgtagcaca gagaatatat agggatttac aagaaaaaag agtggaaata tcgatagaag
     9601 tgattgtaga ctatgttcga agacatgcag aatacattca actgatgaaa caacaaataa
     9661 aaaaaaaatt ctaaataatg aagaatactt atattattgg tgaaataggg cagaatcata
     9721 atggttctgt tgacttggct aagttgatta ttgaattaat ctcacgacct gtacatgagg
     9781 atgtttttgg tatggatttc atgccaatga atgctgttaa aatgactaaa agagatttat
     9841 cagaagaatt ggctgtttct caaatgaatc aaatatatga caatcctaat tcttttgggc
     9901 gtacttatgg tgaacatcgt gcttttcttg agcttgatga tcaagcgcat tttgagattt
     9961 ataaatatgc taagtcatta ggattagatt ttatcgagac gttatgtgcc aaaggatgtc
    10021 tgtctttgct taaactgttc acaccggata ggctaaaagt tgctagtcgt gatttgacta
    10081 acttaccatt gcttgaagca ttagcagaaa ctcatattcc tattatatta tcgacaggaa
    10141 tggctggtca aagagaactt gacaatgcat tagatgtgat aacgagatat catagtaata
    10201 tagctattct acattgtgta tctcagtatc caactcatcc aaataatttg aatctacgta
    10261 caataacata tttgaagaag cattacaata agtttgagat aggtttttct gatcatacaa
    10321 taggtatttc tgctgctaca gctgctgtag cgatgggagc ggaaattata gaaaagcatg
    10381 taacaattga tcggcatatg aaaggaacag accagcttgg ctctttaggt ccagatgggg
    10441 ttaatcgtat gattcgagat attcgcatag cagagtgttg gcttggtact gaagatcttt
    10501 atatagaaaa aggggtggag aagtctaaga taaaacttga acgttctatt gccactcgaa
    10561 aatatattcc agcaggtagt attattcaag agtcggacat tcatttactg agtcctggtg
    10621 atggttataa atggatagat aaaaaaaatg taattggtca ttttgctaaa caagatatat
    10681 cagcgaatga aataatatat cctgatttta ttgaatagat atattcctac tgcaacttgt
    10741 attacggtat agagtactgc ctgctataag ctaagtagtg attaataaat aagggtaaaa
    10801 tactaaaaaa atgaaagaga taaagcttat acttacagat attgatggcg tttggactga
    10861 tggcggaatg ttttatgat
//
