LOCUS       c00121_gnlPro..         6731 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EICFGIAC_121.
ACCESSION   c00121_gnlPro..
VERSION     c00121_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 12:09:29
            Original ID  :: gnl|Prokka|EICFGIAC_121
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6731
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6731
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3042:6532]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3043..6532
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..6731
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6731
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             349..1056
                     /locus_tag="ctg121_1"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTNRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             1485..1718
                     /locus_tag="ctg121_2"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(1752..2537)
                     /locus_tag="ctg121_3"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARNVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLVLTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(2570..2842)
                     /locus_tag="ctg121_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             3043..3744
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_5"
                     /sec_met_domain="SucD_FumR (E-value: 2.9e-14, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3766..5724
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.7e-55, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             5765..6532
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_7"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-24, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.4e-12, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-07, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 agatgagacg atgtgactgg agttcagacg tgtgctcttc cgatctttct tcatatttat
       61 tattcctttt ggatggcaac ttgtagcgaa tttggaattc cccaatcgga tttggaatcc
      121 gtcaagtaat gaaaaagagg ccaaatcaat catgaaacca atgaataaca aagattgccc
      181 cgtcatcttg acaaaaggac cagagatatt aaaaaatcat tattttcaat gaattataaa
      241 tacaatatac taactcttaa tatttttaat tgcttgcgga ttccaaattc gttattcaag
      301 cgcaagtgca tacattgaat cttgcatcat tttattaaga tactgaccat gaagaaatta
      361 ttatccaccc tgattctttc ggccggcatg agcctgagcg ccaccgcgaa taccactctg
      421 ctggatagct ctatcgtggg atattcggac tttacctccc aaacggcgga tttcggcacc
      481 ctgaaagatt ccgtttccat cacgtctgac gacagcaatc tgacgttatc cgggataacc
      541 ttcaacggat acggtaccaa caaccgcgac gttatgtctg tgacgatggt tcttgatctg
      601 tccaaaatca acactccgga gacctatacc gctctgttta acgccaaaaa cagcagtgta
      661 agctggggcg tgggcctgaa cacgaaccgg aaactccagg gattatggaa caacacctca
      721 tacagcgggc ccgtcgttga caccccgctg ggcacggaag ggtccctgac catttccgta
      781 gtcaccggag atcttggcac ccgcatctat tttggcgaca gcgctacgta ctattccaac
      841 agcggcctga aattcggcaa ccagcaaatt gatcagattc tcatggacgc aggactggct
      901 gaatccatcg aacagctcta catccacgac tccctccttt cccaggaaca agttggtcaa
      961 ctgatgagtg aaatcgccag cattccggaa cccgccacgg cttccctggg cctgctggga
     1021 ctggccgcgc tgatgatgcg ccgccgcagg gcataagcct gtaccgtccg cctccctata
     1081 ttcaaaggcc ggctcacaaa atcgtgagcc ggccttttcc ttatccgttc aaacatctgc
     1141 cgaaaaaaca gaggggaaaa gcttccattt gctgcggcaa cctcacggcc agcacttgac
     1201 ggaaaaatgg cattcagtct cccccggtag ggtcatttca agagcttccg gccccgcccc
     1261 acttccgtac acgccccttt ttcccatgcc gggacagccg gaaccggagc atgcaaagcc
     1321 cggcttccct cagcatccgg aacagcccat cctttcagca atccatttcc ccgcacggtc
     1381 cggatcgctg cggttccgtc cgtcggcaac agactccttc cccgaaacag ggaaaaggag
     1441 tgggaaaatg gctgagcttg aacctttatc ccccgttccc gtccatgaac cttcaaaaac
     1501 agcagctgct actgcgcctg ttccggtatt tcaaaagcag aaaaggagaa ccgcgttttt
     1561 tcaacaaacg gaatatatgc cttctggccg ccgccggcgc ctacatcctg actcccgacg
     1621 aattcctgtt tgacggaatc ggcaggctgg gccttctgga tgacgcggcg gtcatcctgg
     1681 gcgccgtcct caccgtcttt ttcccggacg gggactagag ggccgtaccc tccgccgcgc
     1741 cgcgggcgga actaacggga cgacactttc cggaacttcg gggactgtcc cataaatgtc
     1801 tccggatttt ccaggagaag acgttccgtt tcctgccggg aaaaaccgcg cctgcgcagc
     1861 tcgcaggcca gggccgtcag caccagggga tcggaatccc cccagtccgc tgcggaattg
     1921 gcccagacac ggtccattcc gtacaattcc agaatatccg ccgcccgctt gggattcagc
     1981 ttgctggtgg gataaagggt cagcccggcc cagtaaccgg cctccttcac cagcgggaag
     2041 gtatgttcct cacagtgatc caccagcacg cggcaagggt ccagatccgg acggtttttc
     2101 agggcggaaa gaatcattac ggtcccctta agcttgtctt ccagatgggg agtgtgaatc
     2161 agcacaagct ggttgaggcg caccgccaga tccagatgct cttcaaaaat agtcatttca
     2221 tgggaagtat tccggttcag tcctatttcc ccgatgccga ggacattggg ccggtcaatg
     2281 aactccggaa tcagcttcat cacattccgc gcgaaagcca cgtcctgcgc ctccttggga
     2341 ttgatgcaca gccatgtgta atggtccatg ccgaacttgg ccgccctggc gggttcgcat
     2401 tccgtaagct gtacgaaata atcccggaaa ccgtccgcgg acgaacggtc gtaaccggcc
     2461 cagaacgccg gttcccctac cgccaggcag ccggcctgcg ccatggcccg gtattcgtcc
     2521 gtggtgcggc acaccatatg tatatgaggt tctatgaaag ccatcattct tatttgctga
     2581 ggttcggggc tccgcaggcc gctttggctg cggcggtttc cggcacggtg tcatccctgt
     2641 aggaaagggc ttccagaatg gcccggacgc gtccggggcc ggatgcggat aagaggggaa
     2701 gaacatccat cagggcatgg taacggaaat ccgcctcccc ttccccgcgg tccacccggt
     2761 ccagaaatgc ggccacatcc agaacgccgg cgcgcgccgc tgcgaaatcc gcgtccagca
     2821 cttccttttt acttcttttc atgcacagac gatacgccta tgcggaaagc ctcgtcaagc
     2881 cggaacaggc aacaaaatga taaccattcc aaactgataa acagcaacct ctttccccgg
     2941 cttttcaaaa atccgaaaag cgccggaaat tcaagaagag gcttgccatc cgggcttgaa
     3001 ccgggcatcc tgtgaagacg catttatttc attagagcgc ctatgaatgc actagtaaaa
     3061 accatatgta cattcgtgac atcctccatc ggccgcaaaa tcattgtggc tctgacgggg
     3121 ttatgtttgg tcttgttcct tgcgggacac ctggcaggca accttctcat cttcggaggc
     3181 cctgaatgga tcaacaccta cgcccacggc ctgcactcca tgccggaagc agccctctgg
     3241 ggaatccgcg cggggcttgc ggtgatcttc atcatccacg tctggctgac catccagctg
     3301 aagctggaaa accatgcggc ccgcgaaccc tacgtgttca agaacaccat caaggcaacg
     3361 ctctcctccc gctacatgat ctataccggt ctgaccgtcc tggtgttcct gatctaccac
     3421 ctgtaccagt acaccctgcg cgtaggatac gaccccgccc agttcaccac cttcatttcc
     3481 gacggtacgg tggaaacctt tgacgtgtac aagatgatcg tgaccggatt ttccaacgta
     3541 tggtgctccg ccttctacat cctggccgtt ctgatgctgt tcagccatct gcgccacggg
     3601 gtacagtcca tcttccagac tgtgggcgtc gattcccgca aaatccggcc cttctacaac
     3661 tttatcgcca tcgcctacgg cgcgattatc tgcctgggct tcatctccgt gccggtctcg
     3721 gttcttctgg gtatcatcaa ataaccatca actcctctca aagtcatgat taattttccc
     3781 gtaagcgact ggatgccgga tgccaaaatt ccctccggcc ctattcagga caaatggtcc
     3841 aagtacaagc ttgagtccaa actgatcaat ccgaacaaca agcgcaagta cacggtgctt
     3901 gtggtaggtt ccggcctggc tggcgcctcc gctgctgcca cgcttgccga acttggctac
     3961 aacgtcaaat gcttctgcta ccaggacagc ccccgccgcg cccactccat tgcggcccag
     4021 ggcggcatta acgcagccaa gaactaccag aacgacggcg actccgttta ccgcctgttt
     4081 tacgacaccg ttaaaggcgg cgacttccgc gcccgtgaag ccaatgtcta ccgtctggcg
     4141 gaagtctcct ccaacatcat tgaccagtgt gtggcccagg gcgttccctt cggccgtgaa
     4201 tacggcggcc tgctggacaa ccgctccttc ggtggcgccc agctcaagcg aaccttctac
     4261 gcacgcggac agacgggcca gcagctcctg ctgggtgcct accaggccct ggaaaaggaa
     4321 gtggccaagg gacacattga aatgttctcc cgccatgaaa tgatggatct ggtgctggtg
     4381 gacggcgaag ccaagggcat cgtcacccgc aatctggtta ccggcgaaat caaatcctac
     4441 gcaggggata ccgtcctgct ctgcacgggc ggctacggca acgtgttctt cctgtccacc
     4501 aacgcgatgg gctgcaacgt cactgccgcc tacaaggcct acaagcgcgg tgctttcttc
     4561 gccaacccct gcttcacgca aatccacccc acctgcattc cggtcaaggg cgactaccag
     4621 tccaaactga cgctgatgtc ggaatccctc cgcaacagcg gccgcatctg ggtgcccaag
     4681 tcccgtgaaa ccgcagaaaa aatccgtaaa aaggaaatca agccttccga tgttcccgaa
     4741 gaagaacggg actactacct ggaacgcaag tatccctcct tcggcaacct ggccccgcgc
     4801 gacatttcct cccgcgccgc caaggaagcc tgcgacgacg gccgcggcgt ggccgtcacc
     4861 ggcaagggcg tcttcctgga ttttgcggat gaaatcaagc gcatgggtcg cgaatggatt
     4921 gacggccaat acggcaatct gtttgacatg tacgaagaaa tcacggacga cgacccccat
     4981 gaaacgccca tgatgatcta ccccgcctcc cactacacca tgggcggcct gtgggtggac
     5041 tacaacctca tgtccaatgt gaaggggctg cacgtcctcg gtgaagccaa cttctccgac
     5101 cacggcgcca accgcctggg agcctccgcc ctgatgcagg gcctgtctga cggctacttc
     5161 gtcattcccg ccacgctgcc cgcttacctg acgaccacca aacccggcgc cgtcaccacc
     5221 gccgccccgg aattcaaggc tgcggaagac gaagtgaagg aacgcatcaa caagctcctg
     5281 aatgtgaagg gcaccaagac ggtggactcc ttccaccggg aactgggcct cattatgtgg
     5341 gaagactgcg gcatggcccg cacggaagaa agcctgaccc acgccattga acgcattccc
     5401 cagctccgca aggaattctg ggaaaacgtg cgcgtaaccg gcacggcgga cggcatcaac
     5461 gcggaactgg aaaaagcctg ccgcgtggcc gacttcctgg aattcgccca gctgctctgc
     5521 tatgacgccc tgaaccgcca ggaatcctgc ggcgcccact tccgcgtgga ataccagctg
     5581 ccggacggcg aagctaagcg caacgacgat gaatacgcct atgtagccgc ctgggaatac
     5641 actggcgtgg acagcctgcc tgttctccac aaggaaccgc tgaccttcga gaacgtgcac
     5701 cttgccatcc gcagctacaa gtaaagatag ccaatacatt aacactcaaa agaaagatta
     5761 taacatggct aaaacactca atctcactct caaggtctgg cgccaggaaa accgggaagc
     5821 caagggccgc attgagacct atgccgccaa ggacattccg gtggacgcct ccttcctgga
     5881 aatgctggac atcgtcaatg aaggcctggt caaggaaggc aaggaaccca tccattttga
     5941 ccacgactgc cgggaaggca tctgtggcat gtgctccctg accatcaacg gcattcccca
     6001 cgggccggaa cgccaggtga ccacttgcca gcttcacatg cgcaagttca aggacggcga
     6061 taccgtctgg attgaaccct tccgcgcgaa ggctttccca atcctgcggg acctgatggt
     6121 ggaccgctcc gccctggacc gcatcatcgc cgctggaggc tatattgacg tgcgtaccgg
     6181 ttccgcgccg aacgccaaca acatcgccgt ggaaaaagtg aaggcggacg ccgcctttga
     6241 cgcggccgcc tgcatcggct gcggcgcctg cgtggcctcc tgtaaaaacg cctccgccat
     6301 gctgttcacc tccgccaaga tcgcccatct caatctgctg ccgcagggcc agccggaacg
     6361 ttccaagcgc gtcctggcca tgatgaagca gatggaagcg gaaggctttg gcaactgcac
     6421 gaaccagtat gaatgtgaag ccgcctgccc gaaaggcatc agcgtggaca acatcgcccg
     6481 cctcaaccgc gacttcatgc gggccaacgc caaggaaggc ctctgtttct aaagaagatt
     6541 ccttcttaag acgctctgta aaaactcccg gcggcatcgg ctgtcgggag ttttttcatt
     6601 accaggtttc cttgaaccag gaataaaata ccagacagtt gcttcctcat cgtcgcgcag
     6661 cgtaaaaaat tgttacaccg gaaggcaccc agtaatccag gagaccgtac ttggcaatgc
     6721 cggacgaaac c
//
