LOCUS       c00118_gnlPro..        10479 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MOKPMBAA_118.
ACCESSION   c00118_gnlPro..
VERSION     c00118_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 18:02:31
            Original ID  :: gnl|Prokka|MOKPMBAA_118
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10479
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10479
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1835:6692]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1836..6692
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..10479
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10479
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             2..1318
                     /locus_tag="ctg118_1"
                     /transl_table=11
                     /translation="IGENKWQLSFKEEAYDYFDKAIKLLQGTSSKLEMTMLSYFYGMKM
                     DYLLNDSRSKEALEVGLKREKLLKDIAKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYD
                     QAEKYYQQYLSTENSQTPDGKTYAIPYLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYI
                     SILQKEVKAYKGLKDFEKVAALRESIISIIDGINSKDKQNAALELNAIHKADEQEEYIA
                     EQTLQLRIRNISLAFLGCVTCLILFVLWRIWRHTIIVKYKNKMLAKFINEKLAGKVENK
                     QLFIDGDAEDPIAVPLDLEPETGFSEKDDLSPDEVVESREEEDENKKIFKELNRIVVQD
                     QLYLSPELSREDLAQIVHLNNARFARMIKENTGTNFNGYINELRINYAIQLLKQHPNYT
                     IRAIADEAGFNSTPILYSMFKKKTGMTPYEFKKTQESLG"
     CDS             1389..1751
                     /locus_tag="ctg118_2"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             1836..3068
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_3"
                     /sec_met_domain="HBT (E-value: 1.8e-17, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             3065..4177
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_4"
                     /sec_met_domain="Chorismate_bind (E-value: 2.6e-58,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             4197..5864
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-09, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             5868..6692
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_6"
                     /sec_met_domain="ECH_1 (E-value: 1.7e-82, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             6696..7721
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_7"
                     /sec_met_domain="MR_MLE_C (E-value: 3.6e-30, bitscore:
                     94.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             7718..8824
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_8"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-17, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFL
                     NEWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYI
                     GAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQT
                     EILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVE
                     LFLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIER
                     LLQSSIPVPFVITSVPDRRLGQAVTLLIEGQMEISALGTKLESVLASYYRPKYIYTVNH
                     IPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(8798..9367)
                     /locus_tag="ctg118_9"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             9592..10479
                     /locus_tag="ctg118_10"
                     /transl_table=11
                     /translation="MENMNPESLLRKAQALGEDIKEMESIDVMGAYQQAQTQIKTNRRR
                     SMYNQLMRYAAFLTIPLLLSSLILGYLYWGATDTEEKYAEVMAATGSVIRYELPDHSVV
                     WLNSGSTLRYPTVFKKDNRNVELKGEAYFEVEADRKRPFYVNTPAGLSVYVYGTKFNVN
                     AYEDDNSIETVLEKGKVNVISPDGKTTVQLAPGERLLYNKVDQKLLKGKVDVYEKVAWK
                     DGKLIFRNAELGEIFKRLARHFNVDIQFNNISGKEYKYRATFRNETLPQILDYLAKSAA
                     LKWRTEEAVQQADDT"
ORIGIN
        1 cattggtgaa aataaatggc aattgtcttt caaagaggag gcatatgact attttgacaa
       61 agctatcaaa ttgcttcaag gtacaagttc caaattggaa atgactatgc tttcatactt
      121 ttatgggatg aaaatggatt atctgctcaa tgattcccgt agtaaagaag cattggaggt
      181 tgggttgaag cgcgaaaagc tacttaaaga tatagctaaa ttaccggaaa aaacaaaagg
      241 ctttcttgat ctgcaatata cttacttgta tgcaaaaatg tcgtatatct gctatctgga
      301 aggaaagtat gatcaggcgg aaaaatatta tcaacaatat ttgtcaacag agaattcaca
      361 gacaccggat ggaaaaacct atgcgatacc ttatctgcta gtgtctaaac aatatcagaa
      421 agtcgttgat caatgtcagg attttaagaa attgatgcaa gagcaggata ctgtcaactt
      481 gcagtatatt agtatccttc agaaagaggt gaaagcttat aaaggcttga aggattttga
      541 aaaagtagca gcattacgtg agtctattat ttctattatt gatggtatta acagcaagga
      601 taagcagaat gcggctttgg aattaaatgc tattcataaa gctgacgagc aggaagaata
      661 tattgccgaa cagactttac agttaagaat cagaaacata tcacttgctt ttttgggatg
      721 tgtcacttgt ctcattttat ttgtgctatg gcggatttgg cgtcatacga ttattgttaa
      781 atataaaaac aaaatgctgg caaagtttat caatgagaaa ctggctggaa aagtagagaa
      841 caaacaatta ttcatagatg gagatgcgga agatccgata gctgttccat tggacttgga
      901 accggaaact ggcttttccg aaaaagacga tttatctccg gatgaagtag tggagagtag
      961 ggaggaagag gatgagaata agaaaatttt caaagaactg aatcgtattg ttgttcagga
     1021 tcagttatat ctgtctccgg aattgtcgag agaggatctg gctcagattg tacatttgaa
     1081 taatgcgcgt ttcgcccgga tgatcaagga aaacaccgga actaatttca acgggtatat
     1141 taatgaactt cgtattaact atgcgattca gttattgaag caacatccca attataccat
     1201 tcgtgcgata gctgatgaag ccggatttaa tagtacgcct attctgtaca gtatgttcaa
     1261 gaaaaagact ggtatgactc cttacgaatt taaaaaaacg caggaatcct taggttgatt
     1321 ttggcttttt cgataaacaa ttttccgttt tatcggttta ttcttatgat aactaaatat
     1381 aaacggaaat ggtgcaagtt aggataaagc gagtgtacga agacttttca gagaccgacg
     1441 gatatcgggt gctggtagat aaactctggc cacgtggaat caaaaaagaa tggttgaaat
     1501 atgattactg ggcaaaagat ataacgcctt ccgcagcact gcgcagatgg tttcatgaag
     1561 atattccggg tcactggaat gattttgtcg taatgtatca gaaggaactg gaagcttctc
     1621 aagctgttgc cgattttctg actcttatca aacctcatcc ggtgatcact ttgctttatg
     1681 catccaaaga accggtttat aatcatgccc gaatccttcg tgattatttg gaaatgcatc
     1741 tgaaagagtg aaattaaagt aatttttatc tctttccgct ttcagtcgtt cactcaattt
     1801 cctacctttg taatctaaat caaaatcgtg tgtccatgaa gtataaatta ttagttcttg
     1861 atgtagacgg aacgcttctc aatgatgcaa aagaaattag taaacgtaca ttggctgctt
     1921 tgctgaaagt tcagcagatg ggagtacgta tcgtgttggc atccggccga ccgacttacg
     1981 gtctgatgcc tttagccaaa tccctagaac tcggaaatta tggaggttat atcctttctt
     2041 ataatggttg ccagataatt aatgctcaaa acggagaaat actgtttgag cggaggatta
     2101 atccggaaat gttgccttat ctggaaaaga aggcaagaaa aaataatttc gcactgttca
     2161 cttaccatga tgatacgatc attactgaca ctccggagaa tgaacatatc cagaatgaag
     2221 ctcgcttgaa taatttgaaa gtgatcaagg aagaggaatt ttctgtagca attgactttg
     2281 ctccgtgtaa gtgtatgctt gtcagcgatg acgaggaagc gttggttagt ctggaaggac
     2341 actggaagag acggttgaac ggagctttgg atgttttccg ttccgaacct tattttctgg
     2401 aagtagtgcc gtgtgcgatt gataaagcca acacattggg agctttattg gaagaactgg
     2461 atgtgaagcg tgaagaagtc atcgctatag gagacggtgt gtgcgatgta acgatgattc
     2521 agctggcagg actgggagtg gcgatggggc attcgcagga ttcggtaaag gtctgtgcgg
     2581 attatgtgac agcttccaat gaggaagacg gagtggctct ggctgtcgaa aaggcgataa
     2641 tagcggaagt tcgcgctgca gagattcctt tggaccagtt gaatgcacag gcgcgtcacg
     2701 cattgatggg taatctgggt atccaatata catatgccga cgaagaccgt gtagaggcga
     2761 cgatgccggt agatcaccgt acccgtcagc cgttcggtat tttgcacggt ggagctacgc
     2821 ttgcattggg agaaacagtt gccggactcg gctcgatgat tctctgtcag ccggatgaaa
     2881 ttgtggtagg aatgcaggtc agcggaaatc atatatcttc tgcgcacgaa ggtgatacag
     2941 tacgtgcagt agcgacgatt gtacacaaag gacgttcctc ccatgtatgg aatgtggacg
     3001 tttttacttc aaccaataaa ctggtgtcct ctatacgggt ggtcaacagt gtgatgaaaa
     3061 aaagatgatt gacgaaaaaa gtaacttgac aactattgat gcacttattc agcggaaaca
     3121 gccctttgct gtttatcgtg ttcccgggga gaagtatcct cgtctgttga cagaagatgt
     3181 cggagctgtc cgcttgattt tcgatttgaa agaactgaat ggacaaagag gatttgtgat
     3241 tgctccgttc cgtatagata agtcatgtcc gattgtgttg atacagtccg acaggactgg
     3301 acaaccgttg cctatggaaa tcgtggcaga ggaagagcag gacttgcaaa gttatccgga
     3361 ggaatctttt catacccttt gtactgggaa gtatgcgacc tgttttcata catttattga
     3421 agccttgcgt gatgctacct ttgataaact ggtgctttcc cgtagtctca ctattggaaa
     3481 gaatccggag ttttcccctt cagctgtttt tcgtgcagct tgtcaacgtt atattcattc
     3541 ctatatctat ctgtgttata ctcctcagac gggcgtgtgg ctgggaagta cccccgaaat
     3601 tatattgtcg ggcgaaaaaa atgaatggaa cacagttgcc ctggcaggaa ctcaaccttt
     3661 gcagaatggt aaacttccgc aagtatggga tgacaaaaac cgtcaggagc aggattatgt
     3721 ggcgtcctat atccgtcggc agcttctttc gctgggcatt cgctccacag agagcggacc
     3781 ttatccggct tatgccggtg ccttgtcaca tctgaaaact gatttccatt tctctttgaa
     3841 agataataaa aatctgggag accttctgaa agtcctgcat ccgactcctg ccgtgtgcgg
     3901 actgcctaaa gaagaagcct accggttcat tttggaaaat gaagggtacg atcgtaagta
     3961 ttattccggt tttatcggtt ggctcgatcc ggagggacgc acagatttgt atgtgaatct
     4021 gcgttgcatg cacattgaag acgagcaatt gacactgtat gccggtggcg gattgttagc
     4081 ctcttcagag ttgaatgatg aatggcagga aacggaaaag aaattgcaga ccatgaggcg
     4141 tattcttgtg tctgctccaa taatgatgaa tcactaacaa gctaatcact atcaatatgt
     4201 attcggacaa gaaaaatata ctccagttgg tcgcgctgct tgaggcgcat ggaattacga
     4261 aagtagtgtt atgtcccggt agccgtaatg cacctattgt gcatacgctg tctactcatc
     4321 cgggttttac ttgttatgct atgacggatg aacggagtgc cggttatttt gcgattggtc
     4381 ttgcgctgaa tggcgggcat cctgctgccg tttgctgtac ttccggtaca gcgttgctca
     4441 atcttcatcc tgctgtggca gaagcgtatt atcagaatat acctttagtt gttatctctg
     4501 ccgatcggcc tgctgcctgg attggacaga tggcgggaca gacattgccg cagcccggtg
     4561 tttttcagac attggtgaag aagtcggtaa accttccgga gattcagaca gaagaggatg
     4621 aatggtactg taaccgcttg gtgaatgaag ccttgctgga aaccaaccat catggaaaag
     4681 gtccggtaca tattaatatt cctatatccg aacctttgtt ccagtttacg gtggagtcgc
     4741 ttcccgaagt acgtgtcatt acgcgctatc aggggctgaa tgtatacgac cgggattaca
     4801 atgacctgat cgaacgcttg aacagatatc agaagcggat gattattgtc ggacagatga
     4861 acttgattta cttgtttgag aaacggcata ccaaattgtt atataaacat ttcgtgtggc
     4921 tgaccgagca tatcggtaat cagacagtac ccggtattcc agtgaagaat tttgatgcgg
     4981 cgctttatgc gatgcccgaa gagaaaaccg gccagatgac tcccgagtta ttgattactt
     5041 atggcggaca tgtggtttcc aagcggttga aaaaatatct tcggcagcat ccgcctaaag
     5101 aacattggca tgtgtctgct gatggagaag tggttgacct ttacggttct ctgactaccg
     5161 tcatcgaaat ggacccgttt gagtttctgg agaaaatagc tccattgctg gataaccgcg
     5221 tgccggagta tccccgtgta tgggagaatt attgcaagac cattcccgaa ccggagttcg
     5281 gatattcgga aatgtcggct atcggtgctt tgataaaagc attgccggaa tcatgtgcat
     5341 tgcatctggc aaatagttct gttatccgct atgctcagtt ataccaggtt ccttctacga
     5401 ttgaggtatg ctgtaatcgg ggtacaagcg gcatcgaagg ctcgttgtcc acggcagtgg
     5461 gatatgccgc cggttcggat aaactaaatt ttatagttat aggtgacctt agtttctttt
     5521 atgatatgaa tgctttgtgg aacatcaatg tccgtcccaa tctacgcatt cttttgctga
     5581 ataacggagg aggggagatt ttccatacat tacccggact ggatatgtcg ggtacatcgc
     5641 acaagtatat tacagccgtt cacaagacat ctgccaaagg atgggcggaa gaacgcggat
     5701 tcctttatca acgggtagag aatgaagaac agcttgccga agcgatgaaa accttcacac
     5761 aaccggaagc catggaacaa ccggttctga tggaagtatt cagcaataaa aataaagatg
     5821 cacgtatact gaaagattat tatcatcaac taaaacaaaa atagattatg tcaacacaaa
     5881 gagaatggac aaccatcaga gaatacgaag atatcctctt tgattactat aatgggattg
     5941 cccgcatcac cattaaccgt gaacgctatc gaaatgcatt tactccgact acaacggctg
     6001 aaatgagtga cgcattgcgc atttgccggg aagaagcgga tattgatgtg atcgtgatta
     6061 cgggagctgg tgacaaggct ttctgttcgg gcggtgacca gaatgtgaaa gggcgtggcg
     6121 gctatatcgg caaggacggt gttccccgtc tgagtgttct ggatgtacag aaacaaatcc
     6181 gcagcattcc gaaaccggta attgctgccg taaatggatt tgccattggt ggcggacacg
     6241 tgcttcatgt agtttgcgat ttatcgattg cttcggagaa tgcgatcttc ggacagaccg
     6301 gtcctcgcgt aggtagcttt gatgcaggtt tcggagcctc ttatctggct cgtgtcgtcg
     6361 gtcagaagaa ggcacgtgag atatggttcc tttgccggaa atacaatgcg caggaagcgt
     6421 tggatatggg attggtgaat aaagtagttc cattggagca actggaggat gagtatgtgc
     6481 aatgggcgga agaaatgatg ctgctcagtc cgttggcctt gcggatgatt aaagccggat
     6541 tgaatgccga actggacggc caggcaggta ttcaggagct ggcaggggat gcgaccttgc
     6601 tttactatct gacggatgag gctcaggaag gaaagaatgc atttctggag aaacgtaaac
     6661 ctaactttaa gaaatatccg aagttccctt aaacaatgga ttgcaaaata gacattattc
     6721 cgcgggtgct tcatttcaag cagccggccg gaacttcacg aggcacatac acaacgcgaa
     6781 aagtctggta tcttcatttt actgctcccg aatttcccaa ttgggtaggg atcggggagt
     6841 gcgctcctct gccaaatctt agctgtgatg atcttcccga ttacgaggaa gtgctggcta
     6901 aaatctgccg gcaggtagag aatcagggag gtaagctgga catggaagct ctatgcaagt
     6961 acccttccat cctttttggc ttggagacag ccattcgtca cttttttgaa ggaagctggg
     7021 ctttgtggga tacacccttc tcacgtgggg aagcaggtat tccgataaac gggcttatct
     7081 ggatgggtga cttcaataga atgcttgctc agatagagaa gaagatggag gcgggattcc
     7141 gctgtataaa gttgaagatc ggtgccatca actttgaaga agaactggct ttactccaac
     7201 atatccgctc tcactattct tctaaagaaa tagaattgcg tgtagatgcc aacggagcat
     7261 tctcaccaac agatgcgatg gagaaattga aacgcttgtc cgaactggac ttacattcga
     7321 tagaacagcc cattcgtgcc ggacaatggg aagaaatggc acgtcttact tccgaatctc
     7381 ctttgccgat agctttggat gaggaactga taggctataa tacctgggaa gaaaagcaaa
     7441 gattactttc ggctatccgt ccgcaatata ttattatcaa accttctctt catggcggat
     7501 tagccggtgg cgaggagtgg attgcagaag cggagaaact gaatatcggt tggtggataa
     7561 cttctgctct ggagtctaat atcggtctga atgctatcgc tcaatggtgt gctacttttc
     7621 agaatccatt gccgcaaggg ttaggcaccg ggttactctt tacagataat gtagagatgc
     7681 ctcttgaaat cagaaaagat tgtttgtggt tttgtaaatg atgatattcg accgacaaaa
     7741 acagcgtttg ttgctggagg gaaaggaata tactccgggc gatatacata gccttgtagc
     7801 agaaggtgag ggaaaccacc cttctgctat atgggacttg tatctttttc taaacgaatg
     7861 gtttaatgat gatcctgtga tcactgtaca tacttccggt tctacggggg cacctaaaga
     7921 attgcttgtt cgcaaagatc agatgataca gagtgcacgc ctgacttgtg agtttctgga
     7981 tttaaagcag ggtgaaacgg cattattgtg tatgaacctt cgctatatcg gggcgatgat
     8041 ggtagtcgtc cgttctttga ttgccgggtt gaatcttata gtacgtcggg cttccggtca
     8101 tccattggca gatgtggaca ctcctttaag gtttgcggct atggtgcctt tgcaggtgta
     8161 taatacattt cagatacccg aagagaaaga gaaattaaag caaacggaga ttttaattat
     8221 aggaggcgga gcagttgaca aggctttaga ggaaaaaatc agaaatctgt ccaatgctgt
     8281 ttattcaact tacgggatga cggaaaccct ttctcacatc gctcttcgcc gtctgaatgg
     8341 cgcagcagca tccgatcgtt attatccttt ttcatccgta gagttgtttt tgtcttcaga
     8401 aaatactttg atgattaatg ctccgcttgt ttgcgatgat actctgcaga caaatgatat
     8461 tgcccgcatt tatccggacg gtagttttac gattctggga agaaaggata atgtaatcaa
     8521 tagcggagga attaaagtgc aggcagaaga gatcgaaagg ttacttcagt cgtctatccc
     8581 tgtaccgttt gtgatcactt ccgttccgga tcggcgtttg gggcaggctg ttactttatt
     8641 gatagaaggg cagatggaga taagtgcgct agggactaaa ttggaatcag tcttagcatc
     8701 ttattatcgt cctaaatata tttatacggt aaatcatatt cctcaaacgg gaaatgggaa
     8761 gattaatcgt aaagagtgcc gtgttttagc agagagctta cagttgctcg ggagacagga
     8821 ataataaaaa cagcgggagg taatctttca actcgttccg caggagttcc attgtttttt
     8881 gtttataccg attaatggat tttacgctga gattcatttc ttcggcaatt tccgcatgtg
     8941 ttttgccttc aaagaaactt ttcataaata cggtgcgata gttttccgga agcttattta
     9001 atgtttcgta tagcattcgg tataactcat caagtgtata tacactatct gtttctgttt
     9061 catatagagg agctttcttt tggatatttt cggcataact ccattcatac tcctgatgtt
     9121 tcagaaagtt caaacagctg ttttttacac acatttttat atatcccaat gctgtctctg
     9181 attgcaaatc gaaagagtcg gtatccaact tgtcccatag ggaggtgaat acatccgaaa
     9241 caatgtcctc gcggacttct ttatcatcta caaatctttt tgcatacagg cagaaagggg
     9301 cataataatc ctcgtaaagt tgtttgaaag ctctttcttt agtctgtctg gaaaaagata
     9361 ttttcattat tttgagattc tgtagttttt cattttactt caaatatata ataagaaaat
     9421 cagcatttcc taaaattttc tttctttttt cgtttttggt atgaagctgt ggaaaataag
     9481 atagcttaaa aaataaaata aaaaaaagta tgttatacct gtcccttttc gattacctca
     9541 gttgtactat tagtgtaatt gcaattaaaa gataagattt tgaaagagaa tatggaaaat
     9601 atgaatccgg aatcattgct ccgaaaagcg caggcattag gagaggatat taaggaaatg
     9661 gagtctattg atgtaatggg tgcctatcaa caagcacaga cccaaataaa gacaaacaga
     9721 agaaggagta tgtataatca gttgatgcgt tatgctgcat tcttgactat acctttatta
     9781 ctttcttctt tgattttggg atatttatat tggggagcaa cggatactga agagaagtat
     9841 gcagaagtca tggcggctac aggttcagtc attcgttacg aacttcctga ccattcggtt
     9901 gtctggttaa actccggtag tactttacgt tatcctaccg tttttaagaa agataatcgt
     9961 aatgttgaat taaaaggtga agcctatttt gaagtagaag cggacaggaa acggcctttt
    10021 tacgtcaata ctcctgccgg gttaagtgtc tatgtgtacg gaaccaaatt taatgtgaat
    10081 gcttacgaag atgataatag tatagaaacg gtattagaaa agggtaaagt aaacgttatt
    10141 tcaccggacg gaaaaacaac agttcagtta gctccaggag aacgattgct ttataataag
    10201 gtagatcaga aattgttgaa gggaaaagtg gatgtttatg aaaaggtggc atggaaagac
    10261 ggtaagttga tattccgcaa tgccgagttg ggtgaaatat tcaaacggct ggcacggcat
    10321 tttaatgtag atattcagtt taataatata tcgggaaaag aatataaata tcgtgcgacc
    10381 ttccgtaatg aaacactgcc acagatattg gattatctgg ctaagtctgc tgccttgaag
    10441 tggagaactg aggaggcggt acaacaggca gatgataca
//
