LOCUS       c00166_gnlPro..         7237 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ODBCPAFE_166.
ACCESSION   c00166_gnlPro..
VERSION     c00166_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 11:15:53
            Original ID  :: gnl|Prokka|ODBCPAFE_166
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7237
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..81)
                     /locus_tag="ctg166_1"
                     /transl_table=11
                     /translation="MEKGLRNISTTSQLLTHLSPYLLMTRR"
     protocluster    1..7237
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[162:6126]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      163..6126
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..7237
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..7237
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             163..1581
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_2"
                     /sec_met_domain="ILVD_EDD (E-value: 1.2e-151, bitscore:
                     495.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEIGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNLPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVXXXGHF
                     RRQGRFRRCGRHHV"
     CDS             1604..1981
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_3"
                     /sec_met_domain="ILVD_EDD (E-value: 3.4e-45, bitscore:
                     143.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHISPEAA
                     SGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKKAFTPPMRQREVSKA
                     LRAYGKMVSSADKGGVRIVED"
     CDS             2015..2554
                     /locus_tag="ctg166_4"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVXXXSRRDWHHATDHEMGLSNPQAGGDRMGCFSCFLYRFYRPSGS
                     SCAGFSEGRASRVGGI"
     CDS             2508..3731
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.5e-51, bitscore:
                     162.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLDLAKDAQVGLVEYEYKKVDYVRSYQPEPDINKDRIKAAADLIN
                     EAKKPFCLVGQGVLLGGAEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGN
                     VGPNRKTNECDVLIAIGMRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVAVDVKVLG
                     NAKHTIPMITALLEERKRPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSE
                     ATGNDAVLVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTV
                     CFFTGDGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENP
                     DFVAIAKAYGIAGRAVEKREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVT
                     NMIMGDEK"
     CDS             3747..4301
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_6"
                     /sec_met_domain="ALS_ss_C (E-value: 1.2e-17, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             4308..5033
                     /locus_tag="ctg166_7"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDVEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             5083..6126
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_8"
                     /sec_met_domain="IlvN (E-value: 1.6e-47, bitscore: 150.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.1e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPTDIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(6282..7121)
                     /locus_tag="ctg166_9"
                     /transl_table=11
                     /translation="MHKGLLVVGRGIGQVMFQGNALSGLLMLIGIACSSWTLALLALAG
                     NIASTLAAYLLGYSREDIREGLYGFNGTLVGIAIGVFMRINIGSISLLLMGSALSSGIA
                     RQFNRQNKLPGYTAPFILSVWILLILCRYLFPSLMLPTVATPPGHVPDLLHAFTANIGQ
                     VMFQGNMLTGLFFLLAILVNSRLNAAYTIWGASLPLGMILLPATSIADFNMGLLGYNGV
                     LCAIAAGNHLSIRSLIRATLAILLSIGLQIGGMRLGITTLTAPFVLSVWITNLIIKQ"
     CDS             complement(7164..7235)
                     /locus_tag="ctg166_10"
                     /transl_table=11
                     /translation="QVDDHAAKHIVTGILAQLPELRS"
ORIGIN
        1 ccttctagtc attagtaggt aaggagaaag gtgtgtaaga agttgtgaag tcgtagagat
       61 atttcttaag cctttctcca tatagggaaa ggctttttta ttataaataa atcaaggtag
      121 aggcgtggat aaagcgctct acgaacaaaa aataggaaag agatgaagaa tccgttaaga
      181 agctcattta gcaccgaagg tcgtaggatg gccggagccc gtgcgctatg gcgtgccaac
      241 gggatgaaag aggaacagtt cggcaagcct attatcgcta tcgtaaattc atttacccag
      301 ttcgtgccgg ggcatacgca tttgcatgag atcgggcaat tggtcaaggc cgagatcgag
      361 aaacaaggtt gtttcgccgc tgaatttaat acgatcgcta tcgacgacgg tatcgctatg
      421 gggcacgatg ggatgcttta ctcgcttcct tcacgcgaca ttatcgcgga cagcgtggaa
      481 tatatggtaa atgcccataa ggcggacgct atggtttgca tcagcaattg cgataagatc
      541 acgccgggta tgcttatggc ttccatgcga ttaaatctcc cgacggtgtt cgtgtccggt
      601 ggcccgatgg aggcaggtga gctggatggc cgccatcttg atttgatcga tgcgatgatt
      661 gagtctgccg atacatcggt aagcgatgag cgtatcgagc aggtggaacg ccatgcgtgt
      721 ccgggttgcg gttgttgttc cggtatgttt accgctaact ctatgaactg cttgaacgag
      781 gcgatcggtc tggcgcttcc gggtaacggg acgatcgtgg ctacccataa gaaccgtatc
      841 caacttttcc gtgacgcggc taagcaaatc gttgagaacg cttacaaata ctatcgtgac
      901 ggggatgatt ccgtgttacc tcgcaacatc gctacccgtc aggctttctt gaacgccatg
      961 tcgctggata tcgccatggg ggggtctacc aatacagtgc ttcacttatt ggccgtggca
     1021 caagaagccg gcgccgattt tcatatggag gatatcgata tgttatcccg caagactcct
     1081 tgcctgtgta aggtagcccc gaatacgcac acttatcatg tacaagacgt aaaccgtgcc
     1141 ggtggaatcc tcggtatcat gaacgagttg atgaaagccg ggcttgtgga tggcagcacg
     1201 agacgtgcgg acggcctgac cttggccgag gctgttgata aatacgccgt cacttccccg
     1261 aacgtaacgg aggaggcgat tcgtaaatac aagagcgctc ccgctcatcg gttcagtatc
     1321 cagatgggct cccaagaatc ttattataag gaattagata cggatcgtgc cgaaggttgt
     1381 atccgtgacg tggagcacgc ttattccaag gatggcggct tggctgtttt gagagggaat
     1441 atcgccttgg acggatgtgt cgtaaaaacc gccggtgtgg atgagagtat ttggaaattc
     1501 tccggcccgg cgaaagtnnn nnnnnnnggg cattttagga ggcaaggtcg tttcaggcga
     1561 tgtggtcgtc atcacgtatg aggggccgaa aggggggccg ggaatgcaag agatgttata
     1621 tcctacctct tatataaaga gccgtcactt aggtaaggag tgcgccttga tcacggatgg
     1681 tcgtttcagt ggcggtacgt ccggtctttc tatcgggcat atctctcccg aggccgcttc
     1741 cggtggcgct atcggactgg tgagagacgg ggatatcatc gagatcaata tcccggaacg
     1801 ttccatcaac gtgcggttga gcgacgagga gttggccgag cgccgtaagg cggaagaggc
     1861 acgtggaaag aaagccttta cgccgccgat gcgtcagcgt gaggtctcga aagcgttgag
     1921 agcgtacggg aagatggtta gctccgccga taagggaggt gtaaggattg ttgaagatta
     1981 aagccaataa tatacattaa acacgttatt tcttatggag aaacaaaaga taaccggttc
     2041 ggaagctttg ctgaaagcgt tgattgctga aggagtagat actatcttcg gttatcccgg
     2101 aggacaggcg atacctattt acgacagttt atatgattat agggaccagt tgaggcatgt
     2161 attggtgcgc cacgagcaag gcgctaccca tgcggctcaa ggatatgccc gtgtatccgg
     2221 caaggtagga gtgacgttgg ttacttccgg cccgggcgct acgaatacca tcacgggtat
     2281 cgctgatgcg ctgatggata gtacgccaat ggtcgtaatc gccggtcaag taccctcgcc
     2341 gttgttggga accgatgctt ttcaggaagt nnnnnnnnnn agtcgacgtg attggcatca
     2401 cgcaaccgat cacgaaatgg gcttatcaaa tccgcaagcc ggaggagatc gcatgggctg
     2461 tttctcgtgc tttttatatc gcttctacag gccgtccggg tccagttgtg ctggatttag
     2521 cgaaggacgc gcaagtaggg ttggtggaat atgaatataa gaaggtcgat tacgtacgta
     2581 gttatcaacc ggagccggat atcaataagg atcgtatcaa ggccgccgcc gatttaatca
     2641 atgaggcgaa gaaacccttc tgtctggtcg gacagggagt attgttaggc ggtgcggaag
     2701 aggaattgaa agcgtttctc caaaagaatg atatacctgc cggatctacg gtattgggct
     2761 tatctgcgtt gccaaccgat ttcccattga acaagggaat gctcggcatg catggaaacg
     2821 tagggccgaa ccggaaaacg aatgagtgtg atgtattgat cgctatcggt atgcgtttcg
     2881 acgaccgtgt gactggcgat ttaaagacat acgctaagca agccaagatt atccatctgg
     2941 atatcgacaa ctcggaaatc ggcaagaatg ttgccgtgga cgtaaaggtg ctggggaatg
     3001 ccaagcacac gataccaatg atcacggcgt tgttagaaga acgtaaacgt ccggaatgga
     3061 atgccgagtt cgatcgggac gagaaagagg aatacgataa ggtaatcgag aaggaattgt
     3121 atccgaccga gggccaactg aaaatgggcg aggtagtccg taaggtttcc gaggcgaccg
     3181 gtaacgacgc tgtattggtg accgacgttg ggcagaacca gatgatgggc gtccgctatt
     3241 tcaaatataa acaaacccgt agcgtggtga cttccggtgg tttaggtacg atgggatttg
     3301 gtctgccggc cgctatgggc gctaagttcg gagctccgga ccgtacggtc tgcttcttta
     3361 ccggtgatgg gggtatgcag atgacgattc aagaattggg taccatcatg caggaaaaac
     3421 tgaacgtgaa gattatcatt cttaataata acttcttagg tatggtacgt cagtggcaag
     3481 aattgttctt ccacgagcgt tattcaaaca ccatcatgga gaatccggat ttcgtggcga
     3541 tcgctaaagc ctatggtatc gccggccgtg ccgttgaaaa gcgggaggag ctggacgacg
     3601 ctatcgctga gatgctaaac cacgacggcg cttacgtgtt ggtcgctaac gtggagactt
     3661 gcggaatggt atatccgatg gttcctgccg ggggaagcgt gacaaacatg attatgggag
     3721 acgagaaata aggaggagat gaagctatga caacaaagaa attatatacc gttattatct
     3781 tttcagagaa tatcgtaggt cttttgaacc agataacgat tatctttaca cgccgacagc
     3841 tgaacatcga gactctgtcc gtctctccgt ccgctatcaa gggcatccat aagtttacga
     3901 tcacgacatt cgccgatgag gatatgatcg ataaggtggt gaaacagatc gataaacgtg
     3961 tggatatctt gaaggcttat tataatacgg atgaggattt ggtttatcaa gagatcgctc
     4021 tttataagct aagtaccgag cttttcatca agatgggaac cgtggaggga ttgatccgta
     4081 aatacaacgc tcgtatcttg gagatgaacg agacctgcgt ggtattggag aagagtggcc
     4141 attatgacga gacacaagcc ttgttcaatg agttgagcga gacgatcggt gtcctgcaat
     4201 tcatccgctc cggacgtgtg gctatcacga agagcaaggt ggagcgcttg agcgatatgt
     4261 tggccgatat ggagcgaaag ttacatgaaa agcaacaata ataagatatg gagaaagtag
     4321 gattatttca tttcgtggcg gagccgtatt tgatggattt taggggacgt gtaacgctcc
     4381 ctatgattgg taactatttg attcacgccg cttccagcca tgccggagag cgtgggttcg
     4441 gtttcaatga tatgtcggag cgtcatacgg cttgggtgtt gtcccgtctg gctatcgaga
     4501 tgaaggaata tcctaccgcc ttcgataaga ttaatctata cacttggatc gatgaggtcg
     4561 gacgcctctt caccagccgt tgttttgagc tggcggatga gaatgggaaa acctttggat
     4621 ttgcccgttc tatttgggcg gctatcgacg tggagacccg ccgtcctacc ttattggatg
     4681 tagaggcatt gggcaaatat atcgacgagc gtccgtgccc gatcgagaag ccgggcaaga
     4741 tcatgccggc ggagaataag gcggagggaa tcccgtattc gatcaaatac agcgacttgg
     4801 atatcaacgg tcacttcaat agcgtgaagt atatcgagca tctgctggat ttgttcgata
     4861 tcgaccagtt caagacccgt gagatcggcc gtctggagat cgcctaccaa tccgagggta
     4921 aacaaggtat gccgcttacg cttcataagg cggagtccgc tcccgataag caagacatgg
     4981 ctatttgcca tgagggaaag gcgatctgtc gtgcggcggt tacttggaga taataaaaga
     5041 gatacataaa taggttttta aacattaata gttaaaaaga aaatggcaca aatgaatttt
     5101 ggcggtgttg tagagaatgt aatgacccgc gaggaatttc cgttggaaaa ggcaagagag
     5161 atattaaaag atgagacaat cgctgttatc ggctatggcg tacagggacc gggacagtca
     5221 ttgaaccttc gtgacaatgg cttcaacgta atcgttggcc agcgccaagg taagacttac
     5281 gagaaagcgg ttgaggacgg atgggttccg ggtgagactc tgttcggtat cgaggaggct
     5341 tgcgacaagg ccacgatcat catgtgctta ttgtccgacg ctgccgtaat gtctgtatgg
     5401 cctacgatga agccttatct gacagctggc aaggccctgt atttctctca tggtttcgcg
     5461 atcacttgga acgatcgtac gggcgttgtt cctcccacgg atattgacgt gatcatggtc
     5521 gctccgaagg ggtctggtac gtctttgcgt tccatgttcc ttgagggtcg tggcttgaac
     5581 tcttctttcg ctatctatca agacgctact ggcaaggcaa tggatcgtac gttggcgttg
     5641 ggtatcggta tcggttccgg ttatttgttc gagacgactt tcatccgtga ggctacttcc
     5701 gacttgaccg gtgagcgcgg ttctttgatg ggcgctatcc aaggtttgtt gttggcccag
     5761 tatgaggtat tgcgcgagaa tggacatact ccttccgagg ctttcaacga gacggtcgag
     5821 gagttgactc aatccttgat gcccttattc gccaagaatg gtatggactg gatgtacgct
     5881 aactgctcta cgactgccca gcgtggcgct ttggactgga tgggtccgtt ccacgacgca
     5941 atcaagccgg ttgtcgagaa attgtatgcg aacgtaaaat gcggtaacga ggctcagatc
     6001 tctatcgatt ctaactctaa gccggattat cgtgagaaat tggaggctga attgaaggcg
     6061 ttgcgcgaga gcgagatgtg gcagactgct gttaccgtac gcaagcttcg tccggagaac
     6121 aactaatcca atcttaatcc ttatatatca gcaaaaagag gcgggtcact tacgggtggc
     6181 tcgccttgcg tgtccttgcg gccttggccg ctgtttcttt tacggggatg ttgcttaatt
     6241 tcgtcatagt cgtaatcatt attaaatgga tgatgctgga atcattgctt tattataagg
     6301 tttgttatcc atacggagag tacgaatggg gcggtaaggg tcgtgatccc cagacgcatg
     6361 ccgccaatct gtaatccgat agatagtaag atcgccaagg ttgcccgtat caggctacgg
     6421 atagaaagat ggttgcctgc cgcgatagcg cataatacac cgttgtagcc gagcaacccc
     6481 atgttaaaat cagcgatgct tgtcgccggt agtaatatca tccccaatgg cagcgacgcg
     6541 ccccatattg tgtaggctgc gtttaagcgt gagtttacta agatggcaag aagaaagaat
     6601 agccctgtta gcatattgcc ttgaaacatc acttgtccga tgttagcggt gaaagcatga
     6661 agtaaatcgg ggacatgccc gggaggagtc gctacggttg gaagcatcaa cgaagggaat
     6721 agatatcgac ataggattaa taaaatccat accgaaagta tgaatggggc tgtatatccc
     6781 ggtagtttat tctggcgatt gaattgccgg gcgatcccgc ttgataaggc ggatcccata
     6841 agaagcagag atatcgaccc gatatttatt ctcatgaata ctccgatcgc tatacctacc
     6901 agtgttccgt tgaaaccata tagtccttcg cgtatatctt cgcgagaata tccgaggaga
     6961 taggccgcca gcgtgcttgc gatattgccg gctaacgcca ataacgctaa agtccatgaa
     7021 ctacaggcaa tacctatcag cattaatagt ccggaaagag cattgccttg aaacatcact
     7081 tgaccgattc cccggcctac aacgagtaat cccttatgca taccatttta gttttgactg
     7141 cgaaaataac gaaaatagca caatcacgag cgtaattcgg gcaactgtgc caagattccg
     7201 gttacgatat gttttgcggc atgatcgtca acctgtt
//
