LOCUS       c00025_gnlPro..        13701 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IJPINMDN_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 11:17:42
            Original ID  :: gnl|Prokka|IJPINMDN_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13701
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13701
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[211:3701]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      212..3701
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13701
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13701
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(212..1042)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_1"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.1e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1020..2951)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.2; E-value:
                     4e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-54, bitscore:
                     176.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.1e-38,
                     bitscore: 120.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVLVVGSGLAGA
                     SAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKGGD
                     FRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRTFYARGQTGQ
                     QLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEIKSYAGDTVL
                     LCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVKGDYQSKLTL
                     MSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFGNLAPRDISS
                     RAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEITDDDPHETP
                     MMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQGLSDGYFVI
                     PATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFHRELGLIMWE
                     DCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVADFLEFAQLLC
                     YDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLHKEPLTFENV
                     HLAIRSYK"
     CDS             complement(3000..3701)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="SucD_FumR (E-value: 1.8e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3902..4174
                     /locus_tag="ctg25_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4177..4983
                     /locus_tag="ctg25_5"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWAXXXXDS
                     DPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5017..5424)
                     /locus_tag="ctg25_6"
                     /transl_table=11
                     /translation="MQSPASLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSPKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLDLLDDAAVILGAVLTVFFPDGD"
     CDS             5599..5778
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MFERIRKRPAHDFVSRPLNIGRRTVQAYALRRRIISAASPSRPRE
                     AVAGSGMLAISLIS"
     CDS             5775..6116
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="LTNLFLGKEGVVDVELFDGFSQSCVHENLINLLVAEFQAAVGIVR
                     SAVAKIXXXXVPRSPVTTEMVRDPSVPSGVSTTGPLYEVLFHNPWSFRSVFRPTPQLTL
                     LFLALNRAV"
     CDS             6126..6413
                     /locus_tag="ctg25_9"
                     /transl_table=11
                     /translation="VLILDRSRTIVTDITSRLLVPYPLKVIPDNVRLLSSDVMETESFR
                     VPKSAVWEVKSEYPTIELSSRVVFAVALRLMPAERIRVDNNFFMVSILIK"
     CDS             6591..6680
                     /locus_tag="ctg25_10"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLQVAIQKE"
     CDS             complement(6937..7185)
                     /locus_tag="ctg25_11"
                     /transl_table=11
                     /translation="VLAVGAAVPPAAYKYVLDVSCIKSITDWLTARKRYVNAASRSRGE
                     PSREEKLNVRLIPAAVVPVLVLQPMTELSEPFSTRKP"
     CDS             7217..7426
                     /locus_tag="ctg25_12"
                     /transl_table=11
                     /translation="LTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             complement(7644..7778)
                     /locus_tag="ctg25_13"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGRYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(7890..8090)
                     /locus_tag="ctg25_14"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             complement(8104..8952)
                     /locus_tag="ctg25_15"
                     /transl_table=11
                     /translation="MGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENGR
                     PRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEW
                     LSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKK
                     PNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPDS
                     LRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKGE
                     P"
     CDS             complement(9333..10106)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_16"
                     /sec_met_domain="adh_short_C2 (E-value: 1.9e-75, bitscore:
                     244.9, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10208..10726)
                     /locus_tag="ctg25_17"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(10790..12400)
                     /locus_tag="ctg25_18"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             12523..13230
                     /locus_tag="ctg25_19"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQTYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPILVQRIF
                     QSDQQNEAKAAAE"
ORIGIN
        1 ggggcttgct taggtttcgt ccggcatttc caagtacggt ctcctggatt actgggtgcc
       61 ttccggtgta acaatttttt acgctgcgcg acgatgagga agcaactgtc tggtatttta
      121 ttcctggttc aaggaaatct ggtaatgaaa aaactcccga cagccgatgc cgccgggagt
      181 ttttacagag cgtcttaaga aggaatcttc tttagaaaca gaggccttcc ttggcgttgg
      241 cccgcatgaa gtcgcggttg aggcgggcga tgttgtccac gctgatgcct ttcgggcagg
      301 cggcttcaca ttcatactgg ttcgtgcagt tgccaaagcc ttccgcttcc atctgcttca
      361 tcatggccag gacgcgcttg gaacgttccg gctggccctg cggcagcaga ttgagatggg
      421 cgatcttggc ggaggtgaac agcatggcgg aagcgttttt acaggaggcc acgcaggcgc
      481 cgcagccgat gcaggcggcc gcgtcaaagg cggcgtccgc cttcactttt tccacggcga
      541 tgttgttggc gttcggcgcg gaaccggtac gcacgtcaat atagcctcca gcggcgatga
      601 tgcggtccag ggcggagcgg tccaccatca ggtcccgcag gattgggaaa gccttcgcgc
      661 ggaagggttc aatccagacg gtatcgccat ccttgaactt gcgcatgtga agctggcaag
      721 tggtcacctg gcgttccggc ccgtggggaa tgccgttgat ggtcagggag cacatgccgc
      781 agatgccttc ccggcagtcg tggtcaaaat ggatgggttc cttgccttcc ttgaccaggc
      841 cttcattgac gatgtccagc atttccagga aggaggcgtc caccggaatg tccttggcgg
      901 cataggtctc aatgcggccc ttggcttccc ggttttcctg gcgccagacc ttgagagtga
      961 gattgagtgt tttagccatg ttataatctt tcttttgagt gttaatgtat tggctatctt
     1021 tacttgtagc tgcggatggc aaggtgcacg ttctcgaagg tcagcggttc cttgtggaga
     1081 acaggcaggc tgtccacgcc agtgtattcc caggcggcta cataggcgta ttcatcgtcg
     1141 ttgcgcttag cttcgccgtc cggcaactgg tattccacgc ggaagtgggc gccgcaggat
     1201 tcctggcggt tcagggcgtc atagcagagc agctgggcga attccaggaa gtcggccacg
     1261 cggcaggctt tttccagttc cgcgttgata ccgtccgccg tgccggttac gcgcacgttt
     1321 tcccagaatt ccttgcggag ctggggaatg cgttcaatgg cgtgggtcag gctttcttcc
     1381 gtgcgggcca tgccgcagtc ttcccacatg atgaggccca gttcccggtg gaaggagtcc
     1441 accgtcttgg tgcccttcac attcaggagc ttgttgatgc gttccttcac ttcgtcttcc
     1501 gcagccttga attccggggc ggcggtggtg acggcgccgg gcttggtggt cgtcaggtaa
     1561 gcgggcagcg tggcgggaat gacgaagtag ccgtcagaca ggccctgcat cagggcggag
     1621 gctcccaggc ggttggcgcc gtggtcggag aagttggctt caccgaggac gtgcagcccc
     1681 ttcacgttgg acatgaggtt gtagtccacc cacaggccgc ccatggtgta gtgggaggcg
     1741 gggtagatca tcatgggcgt ttcatggggg tcgtcgtccg tgatttcttc gtacatgtca
     1801 aacagattac cgtattggcc gtcaatccat tcgcggccca tgcgcttgat ttcatccgca
     1861 aaatccagga agacgccctt gccggtgacg gccacgccgc ggccgtcgtc gcaggcttcc
     1921 ttggcggcgc gggaggaaat gtcgcgcgga gccaggttgc cgaaggaggg atacttgcgt
     1981 tccaggtagt agtcccgttc ttcttcggga acatcggaag gcttgatttc cttcttacgg
     2041 attttttctg cggtttcacg ggacttgggc acccagatgc ggccgctgtt gcggagggat
     2101 tccgacatca gcgtcagttt ggactggtag tcgcctttga ccggaatgca ggtggggtgg
     2161 atttgcgtga agcaggggtt ggcgaagaag gcaccacgct tgtaggcttt gtaggcggca
     2221 gtgacgttgc aacccatcgc gttggtggac aggaagaaca cgttgccgta gccgcccgtg
     2281 cagagcagga cggtatcccc tgcgtaggat ttgatttcgc cggtaaccag attgcgggtg
     2341 acgatgccct tggcttcgcc gtccaccagc accagatcca tcatttcatg gcgggagaac
     2401 atttcaatgt gtcccttggc cacttccttt tccagggcct ggtaggcacc cagcaggagc
     2461 tgctggcccg tctgtccgcg tgcgtagaag gttcgcttga gctgggcgcc gccgaaggag
     2521 cggttgtcca gcaggccgcc gtattcacgg ccgaagggaa cgccctgggc cacacactgg
     2581 tcaatgatgt tggaggagac ttccgccaga cggtagacat tggcttcacg ggcgcggaag
     2641 tcgccgcctt taacggtgtc gtaaaacagg cggtaaacgg agtcgccgtc gttctggtag
     2701 ttcttggccg cgttaatgcc gccctgggcc gcaatggagt gggcgcggcg ggggctgtcc
     2761 tggtagcaga agcatttgac gttgtagcca agttcggcaa gcgtggcggc agcggaggcg
     2821 ccagccaggc cggaacctac cacaagtacc gtgtacttgc gcttgttgtt cggattgatc
     2881 agtttggact caagtttgta cttggaccat ttgtcctgaa tagggccgga gggaattttg
     2941 gcatccggca tccagtcgct tacgggaaaa ttaatcatga ctttgagagg agttgatggt
     3001 tatttgatga tacccagaag aaccgagacc ggcacggaga tgaagcccag gcagataatc
     3061 gcgccgtagg cgatggcgat aaagttgtag aagggccgga ttttgcggga atcgacgccc
     3121 acagtctgga agatggactg taccccgtgg cgcagatggc tgaacagcat cagaacggcc
     3181 aggatgtaga aggcggagca ccatacgttg gagaatccgg tcacgatcat cttgtacacg
     3241 tcaaaggttt ccaccgtacc gtcggaaata aaggtggtga actgggcggg gtcgtatccc
     3301 acgcgcaggg tgtactggta caggtggtag atcaggaaca ccaggacggt caaaccggta
     3361 tagatcatgt agcgggagga gagcgttgcc ttaatggtgt tcttgaacac gtagggttcg
     3421 cgggccgcat ggttttccag cttcagctgg atggtcagcc agacgtggat gatgaagatc
     3481 accgcaagcc ccgcgcggat tccccagagg gctgcttccg gcatggagtg caggccgtgg
     3541 gcgtaggtgt tgatccattc agggcctccg aagatgagaa ggttgcctgc caggtgtccc
     3601 gcaaggaaca agaccaaaca taaccccgtc agagccacaa tgattttgcg gccgatggag
     3661 gatgtcacga atgtacatat ggtttttact agtgcattca taggcgctct aatgaaataa
     3721 atgcgtcttc acaggatgcc cggttcaagc ccggatggca agcctcttct tgaatttccg
     3781 gcgcttttcg gatttttgaa aaaccgggga aagaggttgc tgtttatcag tttggaatgg
     3841 ttatcatttt gttgcctgtt ccggcttgac gaggctttcc gcataggcgt atcgtctgtg
     3901 catgaaaaga agtaaaaagg aggtgctgga cgcggatttc gcagcggcgc gcgccggcgt
     3961 tctggatgtg gccgcatttc tggaccgggt ggaccgcggg gaaggggagg cggatttccg
     4021 ctaccatgcc ctgatggatg ttcttcccct cttgtccgca tccggccccg gacgcgtccg
     4081 ggccattctg gaagcccttt cctacaggga tgacaccgtg ccggaaaccg ccgcagccaa
     4141 agcggcctgc ggagccccga acctcagcaa ataagaatga tggctttcat agaacctcat
     4201 atacatatgg tgtgccgcac cacggacgaa taccgggcca tggcgcaggc cggctgcctg
     4261 gcggtagggg aaccggcgtt ctgggccggt tacgaccgtt cgtccgcgga cggtttccgg
     4321 gattatttcg tacagcttac ggaatgcgaa cccgccaggg cggccaagtt cggcatggac
     4381 cattacacat ggctgtgcat caatcccaag gaggcgcagg acgtggcttt cgcgcgggat
     4441 gtgatgaaac tgattccgga gttcattgac cggcccaatg tcctcggcat cggggaaata
     4501 gggctgaacc ggaatacttc ccatgaaatg actatttttg aagagcatct ggatctggcg
     4561 gtgcgcctca accagcttgt gctgattcac actccccatc tggaagacaa gcttaagggg
     4621 accgtaatga ttctttccgc cctgaaaaac cgtccggatc tggacccttg ccgcgtgctg
     4681 gtggatcact gtgaggaaca taccttcccg ctggtgaagg aggccggtta ctgggccggg
     4741 ctgacccttt atcccaccag caagctgaat cccaagcggg cggcggatat tctggaattg
     4801 tacggaatgg accgtgtctg ggccannnnn nnnnnggatt ccgatcccct ggcgctgacg
     4861 gccctggcct gcgagctacg caggcgcggt ttttcccggc aggaaacgga acgtcttctc
     4921 ctggaaaatc cggagacatt catgggacag tccccgaagt tccggaaagt gtcgtcccgc
     4981 taattccgcc cgaggcgcgg cggaggatac ggccctctag tccccgtccg ggaaaaagac
     5041 ggtgaggacg gcgcccagga tgaccgccgc gtcatccaga aggtccagcc tgccgattcc
     5101 gtcaaacagg aattcgtcgg gagtcaggat gtaggcgccg gcggcggcca gaaggcatat
     5161 attccgtttg ttgaaaaaac gcggttctcc ttttctgctt ttgaaatacc ggaacaggcg
     5221 cagtagcagc tgctgttttt gaaggttcat ggacgggaac gggggataaa ggttcaagct
     5281 cagccatttt cccactcctt ttccctgttt cggggaagga gtctgttgcc gacggacgga
     5341 accgcagcga tccggaccgt gcggggaaat ggattgctga aaggatgggc tgttccggat
     5401 gctgagggaa gccgggcttt gcatgctccg gttccggctg tcccggcatg ggaaaaaggg
     5461 gcgtgtacgg aagtggggcg gggccggaag ctcttgaaat gaccctaccg ggggagactg
     5521 aatgccattt ttccgtcaag tgctggccgt gaggttgccg cagcaaatgg aagcttttcc
     5581 cctctgtttt ttcggcagat gtttgaacgg ataaggaaaa ggccggctca cgattttgtg
     5641 agccggcctt tgaatatagg gaggcggacg gtacaggctt atgccctgcg gcggcgcatc
     5701 atcagcgcgg ccagtcccag caggcccagg gaagccgtgg cgggttccgg aatgctggcg
     5761 atttcactca tcagttgacc aacttgttcc tgggaaagga gggagtcgtg gatgtagagc
     5821 tgttcgatgg attcagtcag tcctgcgtcc atgagaatct gatcaatttg ctggttgccg
     5881 aatttcaggc cgctgttgga atagtacgta gcgctgtcgc caaaatannn nnnnnnnggg
     5941 tgccaagatc tccggtgact acggaaatgg tcagggaccc ttccgtgccc agcggggtgt
     6001 caacgacggg cccgctgtat gaggtgttgt tccataatcc ctggagtttc cggtccgtgt
     6061 tcaggcccac gccccagctt acactgctgt ttttggcgtt aaacagagcg gtataggtct
     6121 ccggagtgtt gattttggac agatcaagaa ccatcgtcac agacataacg tcgcggttgt
     6181 tggtaccgta tccgttgaag gttatcccgg ataacgtcag attgctgtcg tcagacgtga
     6241 tggaaacgga atctttcagg gtgccgaaat ccgccgtttg ggaggtaaag tccgaatatc
     6301 ccacgataga gctatccagc agagtggtat tcgcggtggc gctcaggctc atgccggccg
     6361 aaagaatcag ggtggataat aatttcttca tggtcagtat cttaataaaa tgatgcaaga
     6421 ttcaatgtat gcacttgcgc ttgaataacg aatttggaat tccccaatcg gatttggaat
     6481 ccgtcaagta atgaaaaaga ggccaaatca atcatgaaac caatgaataa caaagattgc
     6541 cccgtcatct tgacaaaaga accagagata ttaaaaaatc attattttca atgaattata
     6601 aatacaatat actaaccctt aatattttta attgcttgcg gattccaaat tcgctacaag
     6661 ttgccatcca aaaggaataa taaatatgaa gaaaacactg acatttttaa tcgcgatggg
     6721 aagctttgct gtttcctcgg aggcagcgac cgtttttaat tattacactc ccggtacgga
     6781 taattacaat agtaccatcc atgggtttta tcttggcctg gggtcttctt ccctggctcc
     6841 ttccgattcc tcttctccct cctccctgtc cggagagatc agactggaca gttttacgct
     6901 gcgcggagcc gccaacaatt tgggcgctaa tgtcacttac ggcttcctgg tgctgaatgg
     6961 ctccgacaat tcggtcatcg gctggagcac caatacggga actactgcag cagggattaa
     7021 tctgacgttc agtttttctt ccctggatgg ttctcccctg cttcttgacg cggcattgac
     7081 ataccgtttc ctggccgtga gccagtccgt gatggacttg atgcaggata cgtctaaaac
     7141 gtatttatat gctgcggggg gaacagccgc ccctactgct aacacggaag gagataccgt
     7201 aacgatcagc ggcggattga ctgctcccgg catccgcggc cattatgacg ccgagggagc
     7261 gcctggtgat tctgtcgtta ttacgggagc caacggaacc aatactttca gcttattatc
     7321 cccgattttc acggaaatcc gaggggaaat ggtgccggaa ccagccacgg tttccctggg
     7381 cctgctggga ctggccgcgc tgatgatgcg ccgccgcagg gcttgagctt cctgatggcg
     7441 aaaaatcggc ggatgagagc tgttcttgcg gaacagctct tgttttttat atccagagag
     7501 gaagaattgc ttatccgtat gcgggattca tgccctccgg aaggtacgga atttccgggg
     7561 gcaggaggcc gtatccggtt ttttcggcat ggcggcaatt tgctggaaac gtttttgaga
     7621 cgcagtaccg gaaagctttt tctttaccgg aaaatgccgt caaattcggc agcgcgcttt
     7681 tcgtccatat ggtacacggc agctttcaca tagcggcctt tcaggccgga tagggaaccc
     7741 ctttgcagct cacagacctg gagggccgcc gcatacatat tattcgccgt cctattcccc
     7801 ggcgctggta tttcggaaga acggcaatgg gccccatgcc cagcacttca tattcttttc
     7861 catcgtctgc cctgatgacg gacgttgcat caacgatgtt tcccgacgat gcggctgccg
     7921 tggacggcga ctgcatccag ctccgggatg aaggacggac tgacgcgcat gatatggagc
     7981 aggtaatgtt catggcagcc ggggacgaaa tagttccaga acgcttctct cgtgacatgt
     8041 tccgtttcgg catggtctga ggattgttcc gttcttaatg caatggtcat gaaaggttgt
     8101 tctttacggc tcccccttgg agaaattcca gaggcggtgc atcgtcataa tgtccggaat
     8161 gttcatgggg cgcaccacgc ggaacccgat catgcctccg tccgtcaggt accagatgct
     8221 tttagggttt tgaggatcct gacggttcca ggcgggggtg ctggcgcggc gcgcagcgct
     8281 tctcaggctg tccgggtcgt cttcccacga accgccgcga acgatgtgag gggcgccggg
     8341 gatgatgacc aaggggtctt tcgcgggcaa gccgctccgt ttgccgtagg catccggaac
     8401 gtaagagtcc aaaacccatt ccgccacatt tccgtgcatg tcccggagtc cccacttatt
     8461 tggtttttta gagcctgttt tctggtagcg gtcattggag ttgttccagt accaggcgta
     8521 ctggtccaga gaggcttccc cgtttccgta agaataggcg ccgggggagc cggcccggca
     8581 ggcgtattcc cattccgcct ccgtgggcag gcggtagtaa tgcccggtct gggcgctcag
     8641 ccattcgcag aatttgctgg cggcgtggtg ggacatggag atggcgggca gaccgtgttc
     8701 atagccgtgg cccatgccca ggttcatggc ggtgtagggg gcggtaggct gcgtaacgga
     8761 gtcccacagt tcgtcatccg gctgttcctc cagaagctgg ccgtccttgg cgcgcggacg
     8821 cccgttttcc atgaaggccg tataaagttc ccaggggatt tccgtttccg agatccagaa
     8881 gggggagatg ctcactttat gctgcggacc ttcgtccggt ttccggtgcg gctcttccgc
     8941 gggactcccc atgaggaacg ttcctcccgg tatggcgacc atgcgcaggg aagctcccgc
     9001 cacgggaacc gtttccgtgt aggattcaaa acgtgccgga tttccggaag cttcaatgag
     9061 ctgatggatt tggcgcgttg tgccgaccag ctcccgggac ggcaggtcat ccggaatggg
     9121 aagggcagga ccggcagcgc ggtccagttc ccgtttttgc agcgcggatc ggctttctcc
     9181 ccactggcgt gcgctggtaa tgcgcgcggc atctttcgtg gccgggcggg gggaattatt
     9241 ttcttcccgg cacccggcca gcagggcgct tcctcccaga aagcaggaaa caaggaaaat
     9301 gccgcgcatg gaatggagaa aaccggaatg ccctacatcg tcatgcctcc gtcgcaggca
     9361 atgacctgcc cggtgatgta acgggcatcg tcagaggcaa ggaaggccgt cagggcggcg
     9421 atatcttcca cggaaccttg ttctttcaaa ggtattttct taacgatttc ttccttgaga
     9481 ttgtcgggaa tggcattgga catttccgtg gagatgaagc cgggagcaat ggcgttgcac
     9541 gtgactttgc gcggagcgaa ttcctgagcc agtgatttgg tgaaaccgat gaggcccgcc
     9601 ttggaagcgg cgtaattggc ctgaccgatg ttgccgacga gaccgatgac ggagctcatg
     9661 ttgatgatgc gcccggccgg ggatttcatg agaacacgct ggagggcctt gaccgtattg
     9721 aacgcgcttt tcaggttggt gtccagaacg gcatcccagt cttcctcttt catgcggagc
     9781 atcagggagt cccgcgtgat gccggcgttg ttcaccagga tgtcaatctg cgggaagtct
     9841 ttcaaaatgg cggccatggt ttcctgaacg gccgcgtaat ccgctacgtc gcaggggtag
     9901 gccttgcagg aatccggaaa ttccttgttg atttcttctg cggccccccc gcagctggat
     9961 ggactgcggc tgatcaggat gaccctggct ccttccgaag cgaagcggcg cgcgacggca
    10021 ttgccgattc cgcggcccgc gccggtaacg atggctgttt tacctgctaa cttttgcatg
    10081 ctgcccacag taaacccgtt tttcacggtt ccggcaagct tgaaatggac ttggccgcgc
    10141 aggaacccat acggggaagg ggcgtgccgg gaatgaaaaa agaggggggg agaaacgggg
    10201 cggggggcta ctgtccggcc tcttcatttt cccggagtgc accggggggc gccccgtctt
    10261 catccggttc taccaggtcg ctgaattcat ccgaattttc caaaatgtcc tttaaggcgg
    10321 cggaaccgta atagcgggcc tcaaacaggc gtttgccttc ctgcctgcag cggttgtcca
    10381 gcatttccat tcgtttttcc attttttcta tcaaggcgtc ttctttctcc ttttccgcat
    10441 cgttcaattt atcctgaagc tggaggaaat gccggatgtc cttctgaatg tcctgcagcg
    10501 ttttgacggc gttgtccgcg ctttccttgt cctgaacgcc tgccaacgtc tgctggatat
    10561 tgatggcaaa ggaaaaggcc tggttgatca gggattccgc ggaaggaatt ttttccgccg
    10621 gagccgctgc tgcgggggaa gccgttccgg cggccgtttc accaaatgca agagaggctc
    10681 cggacagaag cgcagaatat aagagaggaa caagaaaagc cttcatcctg ttcttttaag
    10741 gcaggatgaa atccacggca aggaaaaagg ggaaactgaa aaaagagcct tattccgccg
    10801 tgatgccgcc tttttcatcg tccagaatgc ctgacttttc cagatagtag tcatatccac
    10861 ctgcgtaggc ggtgatggtc ccccggttca catgcagggt tttttgtgcc agggaacgga
    10921 tgaagtgcac atcgtgggag atgaagacca gtgttccttc ataatgcttc agagcctgca
    10981 ccagggcttc tacggacaaa aggtccaggt gggtggtcgg ctcgtccatc agcaggaggt
    11041 tgggcggatc caccaggaat ttgaccaggc tgagccgcga tttttccccg ccggaaagaa
    11101 cgctgacgcg tttttccaca tccagcctcc ggaacaggaa ggaacccagg atggaacgcg
    11161 cttcttcctc ccggatttca gcgctgcatt tcatgatttc ctccagcacg gtattttccg
    11221 gattcaggtt ttccgttcgc gcctgggaga agtagccgat gcgcgtcgtg gtaccgggag
    11281 tgcgttgtcc ggagtcaatg gggatgatgc ccgccaggat tttgagaaga gtggatttgc
    11341 ccgcgccgtt cgggcctaca agaacagtgc gctccccgcg ttccaccagc aggtccaggt
    11401 tttcataaac cctgcggtcg ccataggatt ggcagacttt ttccagctca atgactttct
    11461 gggtgctgcg cggaggctgg gggaagttga atttaaatac tttcctgcgg gctaccggtt
    11521 tttgaatgat tttcatcttt tccagctgct tgatgcggct ctggacttgc ccggctttgg
    11581 aattgatgga gcggaaacgg tcaataaatt cctgaatgtg cgctatttcc ttctgctggt
    11641 tgcggtaggc cgcctgaagc tgctcgaagc gcacgtcctt ttgttggagg aagtccgagt
    11701 aattgccgcg gtattccacc agttcttcgt tgtcgatgtc gtacacgctt tccaccagct
    11761 catccatgaa atcccggtcg tgggaaatca tcaggatggc tccggggtag tttttcaggt
    11821 atcgctggag ccacagcagg gacaggaggt ccaggtggtt ggtaggttcg tccagcatca
    11881 ggaggtccgg ctccaggaca aggagcttgg ccaggtacgc gcgcatgatc cagccgccgg
    11941 acatttcccg ggcggggcga tggaagtcgc tttcccgaaa ggccagccct ttgagaattt
    12001 tcttggcttt gggctccagc tggtaaccgt tggcggcgtt gaaagtgtca atggcttccg
    12061 cgtattccgg cgtatccgtt ttgttggcgt tttccgccgt ccggatggtg tggatggcct
    12121 gttccatttc cggcgtgatg cccagggcga tttccagaac ggtttcatcc ttcggttcgc
    12181 tggcttcctg gggaagatag cccacgatgg cgtattcatc catgctgatg gagccttcgt
    12241 ccggcgtgtc ttctcccaga atcatgcgga acagggtgga tttgcctgct ccgttggggc
    12301 caaccagagc cacccgttcc ccccagttaa tggtcatttc cgtttccctg aacaaggtcc
    12361 gtccggcgtg ggattttgtg agatttttga tcgtcagcat ggtgaagaga ggatgtattc
    12421 taccgggatg gaaaggggaa ggcaagagcc gtcagggcgg aggcaggcat ttttgaaagc
    12481 tttactggat ttttacgcgt agtctgctag ccttggcgcg ccatgccgac cacgcagaca
    12541 ttcaggcttt tgcttgctgc cgcccttttg tgcggatgga gttcctgctg tactcctccg
    12601 gcggaggatt atatacaaca aacttacgtg cagcagcaaa tgtccgggct ggctaatgcc
    12661 ttcctggcgc tgctgccgcc ggatcaggcc tctcttcccg ctgccggagc ggaggccagg
    12721 tggctggcgg acacggccgt ggtccagtcc gccgcgattg cccgggacaa caggactgtg
    12781 ctgtttggct ggctgaacaa tattctggtc aattccaacc tgcgcgacag ggggttgtgc
    12841 tggcaggtcc agcaggattt gtaccgggac ctgcgccgcc gccccgtgaa gtatttccgc
    12901 atagggctga cgattcgaga ccgaggaacg ggcagggagc acagttgcgt gtatgtcaat
    12961 gccgcgggga agggattgca gggctccatt gttctggatg cctggaagaa ctgcgggcat
    13021 ctggtgacgc tgacccagaa ggaccgggaa ggcggcaaat gggaggagga ctggcgggaa
    13081 ccatttgttt ccaaggcctt tccggagggc cattcctacg gcatggaaca tcacctggtc
    13141 tggcccgggt gggccaggaa acgccccatt ctggttcagc ggatattcca gtccgatcag
    13201 cagaatgagg cgaaggcggc cgctgaataa aggggaagcc tgatccggca ggaaccggca
    13261 cacggtgctg cgccgcggcg gtttgcggta tcctccgttt ttaaggaaaa tcccggcgaa
    13321 tcggcaaatg gcggagggaa tccggactca gggcaaataa aaacgcactc agtgcgtaca
    13381 ccgagtgcgg attaattgga taatttgcta gtgttgcagg gcaaaacccc gctgcaaact
    13441 tacttgccct tggcctgcac aaccggagcg ggagcaggag cggtggtttg ctgttgctgc
    13501 tgctgctggg agcaggaagc gaccaggcaa gcggcgccgg cgatggcgag gatagcgatg
    13561 ttcttcataa ttcgaattaa atacagtgtt tgttaactac tggaacctcc gcatccacgg
    13621 aggtttgctg gcaccaatgt aaatggtggc aagtagaaat caagagattt tcttgttcca
    13681 tgtcacggca ttacagaaaa g
//
