LOCUS       gnlProkkaLPLLAMEF_17   10725 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LPLLAMEF_17.
ACCESSION   gnlProkkaLPLLAMEF_17
VERSION     gnlProkkaLPLLAMEF_17
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 07:08:04
            Original ID  :: gnl|Prokka|LPLLAMEF_17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10725
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10725
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1411:5725]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1412..5725
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10725
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10725
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..185
                     /locus_tag="ctg17_1"
                     /transl_table=11
                     /translation="MNGQVTKVKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFS
                     SLGMMIASIANLIKK"
     CDS             200..1348
                     /locus_tag="ctg17_2"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1412..2131
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-16, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2152..3453
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3470..4594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.9e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4604..5725
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg17_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.3e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4694..5701
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg17_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg17_6_Aminotran_5.1"
                     /locus_tag="ctg17_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5722..5865
                     /locus_tag="ctg17_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6068..7552
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.4e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7506..7919
                     /locus_tag="ctg17_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSF"
     CDS             7980..8765
                     /locus_tag="ctg17_10"
                     /transl_table=11
                     /translation="MGDHSYDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVL
                     GFPRNDLLISKNNCNVIKREISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDC
                     DLLKLSKILLKFNAALILKLHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMI
                     TDYTSTYFDFLLVNKPVIFNFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMG
                     LLAGKDIHAEHRRHISLLMNQFQDDNSTKRICDIFLNEI"
     CDS             8774..9523
                     /locus_tag="ctg17_11"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             9523..10563
                     /locus_tag="ctg17_12"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 acatgaatgg tcaggtgacg aaggttaagg gtagtggtaa gaaacagatt gagccgggat
       61 gtgagattat tgtgcctggt aaggctaaga agaaagggaa catagctaat attttaggtt
      121 atgctacttc cttcagttct ttgggaatga tgattgcttc tattgctaat cttataaaga
      181 aataatagaa tttactttta tgtcagaaca acgacaggat aaaaacttgc tctctgaacc
      241 acacaagaca gaaagtgatg agatagaaat tgatttggtc gatatctttc gcaagattat
      301 tgctattcgt aaaaaattat acaaagccgt tggaattggt tttattattg gaataattgt
      361 agcggtaagt atccctaaac agtatacagt aaaggttacc ctttctcctg aaatgggtaa
      421 tgcgaagggg agtaatggtt tagccggact tgctgcctcg tttttaggag atggggctct
      481 aataggggaa agcacagatg ccttgaacgc ttctctttca gcagatattg tttcttcaac
      541 tcctttttta ttggaacttt tagaaatgga agtctccgtt tctaaaaagg atgataaaat
      601 gactttgggg tcttatctcg atgaagagtc atctccttgg tgggattatc ttataggttt
      661 tccgggcata gtaataggag gagttaaatc attattcgga gaagatacgg ttcctgccag
      721 tggagggcgg caaggaacta tcgaattgac gaaagaagta aatgagaaga ttaattttct
      781 taaaaagaag attagtgcat ccattgataa gaaaaccgcc ataacgagca ttacggtcac
      841 cttacaaaat ccgcagatca ctgcggttat agcagattct gtcgttcata aattacagga
      901 atatattatt gggtatcgaa cttcaaaagt aaaagaagac tgtgcgtatt tggaacggtt
      961 gtttaaagaa cgtcagcagg aatattatgc tgctcaaaga aaatatgcgg attatgtaga
     1021 cgcccatgat aatgtggttc ttcaaagtgt acgtgctgag caggagcgtt tacagaacga
     1081 catgagtttg gcttatcaga tatatagtca ggttgctaat cagttgcagg tatccagagc
     1141 caaagtacag gaggaaaagc cagtctttgc agtagttgag cctgccgttg tacctttgaa
     1201 accttcaggt atgggactca aaatttatat tttattattt gtgttcctgt ccgtatctgg
     1261 tactctcgtg tgggtgtttt ttggcaaaag tctgctggct agcttgagaa aagaactgaa
     1321 aaataaggag atagaacagg ataaatgatg ctaaaacgtc gtttacaaca ttcttacatc
     1381 aattaaattc acttactata ttattaaacg aatgatacgt acagctatga taatggctgc
     1441 gggcatggga acccgttttg gccaatatac agaattgata cctaaagggt tcgtcaaagt
     1501 gggaggtatt ccaatgatag ttcgttctat tgatactttg ttatcatgtg gcattgagcg
     1561 aattgtaatc ggtacaggat ataaacaaga agtttatgaa gaattgaaga cagactatcc
     1621 tatgcttgaa acctgtttta gtcctcgtta tgctgaaaca aatagtatgt atactttata
     1681 taatacgcgg gagattctgg gcaatgatga ttttttattg ttagagtcag atttgatttt
     1741 tgagaaacaa gcaataatga gcttattgga gtgtcctgcg gcagatgcaa tgctaatagc
     1801 tccagtgaca aagtttcaag atcagtatta tgtggaacat gatgataatt ttcgcctttc
     1861 ttcatgttct gtcaataaga ataaactaaa cgctaaaggc gaattggtcg gcatccataa
     1921 actatccggt tccttttaca aaataatgtg tgctgattat gcgagtattg ttgatgaaca
     1981 acccaatttg ggatatgagt atgaattact acgaatatct tgttctcaat ctcctgttta
     2041 tgtgcataaa gtagaagggc tgaaatggta tgaaatcgat gacatatcag atttggaata
     2101 tgcagagaaa tatattgttc cgtattgtta attaaaataa tatatcaaat tatgagtaag
     2161 acagtttata ttgggatgac tgcggatatt atgcatccag gacttatccg cattattaat
     2221 gaggctacta aatacggtga tgttataatt ggtcttctta cagataaagc tattgcggag
     2281 cataaacgcc ttccttatct gacctatgaa caacgaaaag aggtagttca gaatattaaa
     2341 ggcgtatgta aagttgttcc tcaagaagaa tggagctatg ttgagaatct caaacgcatt
     2401 aaacctgact atataattca tggtgacgac tggaaaaccg ggcctttacg tgaagaacgt
     2461 gtgcgcgtat ttgaagtgat gaatgaacag ggaggaaagg ttatcgaaat tccatatact
     2521 ttgggaatta attcatcttc tttggataaa gatattaagg ctataggtac aacccctgat
     2581 gtacgtttaa aatcacttcg tcgtttgata aatgccaaac ccgtagttcg tattttggaa
     2641 gctcatgatg gactatgtgg cttgataatt gaaaatcagg aaatattaaa aggggataag
     2701 agggaagtat ttgacggaat gtggtctagt agccttacgg attcaaccag taaaggtaaa
     2761 cctgatattg aggcggttga tttaactacc cgattgcaag atttgaataa tattctggag
     2821 tgtactacta aacctattat ttttgatgga gatacaggtg gtaaaattga acatttcgta
     2881 tttacagtac gcactttaga acgtcatgga atttcagcta taataattga agataaagtt
     2941 ggattaaaaa agaattcatt gtttggtaca gatgttattc aaactcaaga tacaatcgaa
     3001 ggtttctgta ataagatcaa agcaggaaag gcatctcaga ttactgatga ttttatgatt
     3061 atcgctcgta ttgagagcct tatagcggga aagccggtaa gtgatgcttt agagagagct
     3121 tttgcatatg tccaagcggg agcggacggt attatgatac atagcaaaaa taagtcgggt
     3181 gaagatataa aagaattttg tttggcgttt cgaaaacagt atgctcatgt acctatcgtg
     3241 gttgtgccta ctacatatga tcatatttat gagtctgaat tgtgtgattg gggtgtgaat
     3301 ataattattt atgctaatca tatgcttcgt gccgcttatc ctgctatgat gaatgtcgca
     3361 aagataatat tagagaatga acgtgcttta gaggtgcgcg aactgtgtat gcccataaaa
     3421 gaaatattgg aactgattcc aggtactaaa taaaaagagg aatatcatta tgttaagcgt
     3481 agaaaaagtt tatgaaacgt ttctgagtca tgacgttgat ttttttacag gagttccaga
     3541 ctcattacta aaaaatattt gtgcctatat cacagaccat acttcacgtg agaaacatat
     3601 catagctgct aatgaaggtg cggctgtagg aattgcttca ggttattata tggcatcagg
     3661 taaggttcct gtggtttata tgcaaaattc cggcttgggt aatactgtta atcctctgct
     3721 gtctcttgca gatgaacaag tatacagttt tccaatgctt ttgatgattg gctggcgtgg
     3781 tgaaccggga acaaaagatg aacctcagca taaaaaacag ggtgaggtaa ctttagattt
     3841 gttgaaagca atgcggattc cttatataat tcttgattca aatgagaatg atgcatttat
     3901 tcagctccat gatatcatac aatcagcaaa aactaagaat attcctcatg caataattat
     3961 tcggaaagat gtttttggca aatataaact tcaaaaagag ttcggatgta attatccttt
     4021 atctcgtgag gatgctttgc aaatagttgt ggattatctg cctgaaaatt cagtggtcgt
     4081 ttctactact ggcaagcttt ctcgtgagtt atttgaatat cgagaaatga aagagcaagg
     4141 tcatgaacat gattttctca cggtaggctc tatgggacat agttcatcaa tctctttggg
     4201 tattgctata gcaaagcaag atagacctgt ttattgcttg gatggtgatg gagcatttat
     4261 tatgcattta ggggcaatta gtaacattgg cgatttatct cctaaaaact attatcatat
     4321 tttgtttaac aatggtgctc acgagtctgt aggaggacag cctactttag gatttagttt
     4381 agatattccg gctattgtcc gggggagcgg atataagcat acttatactg tttgtacaaa
     4441 agttgaaatt gaagaagcaa tgaagcagct tccaaagtta tgtggtcctg ttttgttgga
     4501 aataaaggtt aaaatagatt ctcgggagaa tttgggacgt cccacgacta ctcctataga
     4561 gaataaggag cattttatgg attttttaaa ataaatatat tcgatgaaaa tagaaagaaa
     4621 aatattatta aatcctgggc ctgccactac tactgacagt gtaaaaatgg cacaagttgt
     4681 tccggatatt tgtcctcgcg agaaagaatt cgcaggtatg atgaaacaac ttcgggacga
     4741 tttggtcaga gttgctcatg ggaatttgga aaaacatacc gctgtattat tttgtggctc
     4801 aggaaccatc aatattgata tatgtctaaa ttctcttctt cctgaagaca aaagggtgct
     4861 tatagtgaat aatggggcat atagtacccg tgctgtagaa gtgtgtcaat attatggttt
     4921 gcctcatatt aatttggaat tttccgttta cgaacgtcct gatttatcgg tggtggaaaa
     4981 tgtgttgcaa gaaaatcctg atatagctat ggtttatact actcatcacg agacgggtac
     5041 aggaattctg aaccctattc gcgagatggg cgctatagct cataaatatc aggctaaatt
     5101 tgtcgtcgat actacttctt ctttgggcat gattcctttt gatatagaga aagataatgt
     5161 ggatttttgt atggcatctg ctcaaaaagg acttcaagcg atgacaggtc tttcttttat
     5221 tataggcaat gaggaacaga ttaagttttc aaaaaaatat cccaagcgtt cttactattg
     5281 taatctttat ttgcagtatg agaattttga gagaacaggt gaaatgcatt ttactccacc
     5341 ggtacaaact atttacgcca ctcgtcaggc attaaatgaa tattttgaag tgggtgaaga
     5401 agctaagttt gcccgtcaca aaagagtttt tgaggctatt cattcaggta taaatgaaat
     5461 tggtcttaaa agtgtaataa agcgtgaatg gcagtcagga ctggttgtct cagttcaata
     5521 cccagaagat cccaactggg attttgagaa aatacatgat tattgttatg agcgtggatt
     5581 tacgatttat ccaggtaaga tatcaactga ggatactttt agaatctgtg ctttaggaga
     5641 gatagaagta gatgatattg agaacttctt taaagtacta aaagctgcat taaatcatta
     5701 taacgtcaca ttaccgatgt catgattgca gaaatattat tgaagattcg tcatttttat
     5761 ttttcccttc gtggtataca cttccatccg gaaagtgtta tttctggagt gcctattcgt
     5821 agctttcgct tagtaggcaa atatggcaat attaatttga ggtgatgcat taggagttct
     5881 ttattcttat aaaaaggcat cggtagttat aggagataat gtttgtgtag ggtaatttgc
     5941 ttttagtggg agagaccata ttagaattgc ggtaaggggc gaagaagata ataaccaatt
     6001 agtgagaata ttggaaaaat ataattgata tcggtaaatg tagttgtttt tatactgtat
     6061 ttaagtaatg gaaaatctaa agcagaaaac tgtatcagga ataatgtgga gcgctataga
     6121 acgtttctct ttacaaggag tacagtttat aattcaaata atattagctc gtttgttact
     6181 accatcggat tatggtatga tcgggatgtt agctattttt cttcaagtcg ctcaagtatt
     6241 tatagatagc ggttttacaa atgctttaat ccagaaaaaa gatagaactg aagaggattt
     6301 tgccactgtc ttttatttta atattcttgt cgcagtatta ttctatggta tattgttttt
     6361 ttcggcttct ttgattgcag acttttataa tatgccgact ttagttcttg taattcgttt
     6421 tatagcattg tcgttgataa taaatgcttt atcggctatt cacagaacga aattaattat
     6481 ttctgtaaac tttaaaactc aatctaaaat ttcattaggt gcagctttta tatcaggcgt
     6541 gattggaata tggatggctt atgtcggttg cggggtttgg gctttagttt ggcaaactct
     6601 cttaaatagt ataattttga caattttgtt ttactgttta gttcattgga aacctttaca
     6661 tactttctcc aaaagttctt ttgaaagatt attcaatttc ggatctaaat tattgatctc
     6721 aagtcttatc aatacagtat atcgtaatct gtataccatt gtaataggaa aaaagttttc
     6781 tgttgtagag cttggttact atacaagagc agaacaattt gctatttttc cttccaataa
     6841 tttaaatgct ttagtttcta gagtagcgta tcctatttta agttccattc aagatgatga
     6901 taaatgttta acaaacgcat atcgaaatta tatcagatta tcctcatata taatttttcc
     6961 tttaatggta ggtttacttg ttttggctaa tcctattatt agtctattgt taacagataa
     7021 atggtctggg gttgttattc ttttacagat attatgtttg gattggatgt ttgatcattt
     7081 gagccaaatt aatttgaatt tattatgggt taaaggaaga tctgatctgt cgttacgtct
     7141 tgaaataata aaaaagacga ttgctatatt cattcttttt gtgtcaattc catttgggct
     7201 tgaggtgatg tgttggggta gagttattta ctctctgata gcgacatatt tgaatacata
     7261 ttatactaat tctcttattg atttgacctt aaagttgcaa gttaaagatg tatttccaag
     7321 tttaatactc tctttcataa tgggggggat cgtttttata tgtatttctt tctttgaaac
     7381 tgatatagta aaaattgtga ttggatgtat tactgggatg tccttctata ttttactttc
     7441 ttttcttttt aagctagatt cttttttttg tattttaaca ttgatcatta aaactaaaaa
     7501 catagatgaa aatattaaaa aagatttttc aagtaatagt aaagataatt aaccattgtg
     7561 tgccagttga tagtagatca ttgtatttta ttcctcatcc taattgtaga acagataaat
     7621 atgatattat aaattattcg tcagataatg ttctcgttct gttaaattat ttgctaaaaa
     7681 aagatagtgc tgaatattat aaaatatatg ttgaaattta tgattcttct cgtatttcag
     7741 aatatcaaga atatatttat ggcataaatc ctaatattag gtgtactttt ttatgtgcat
     7801 gtgttggacg ttttttcttt aataaagtat cttttaagga tatgttgtat gccttttttt
     7861 gtttttgtag agcaagtaaa tgttttacag ctacttttta ttatgatttt tcattttaaa
     7921 aacgctctca acagattatt tgtttggggt attatactcc attcaaagat gattatcata
     7981 tgggagatca ttcttatgat aaatttcgta atacaacatg taactcattt gattactcta
     8041 ttgctacttc ttgtttaagt gctagaataa tttcaataga ttgtggaatc tcatatgata
     8101 aattcaaagt cttaggattt cccagaaatg atttgttgat atcgaaaaat aattgcaatg
     8161 ttattaaaag agaaatttcg aaatttgcgg gatatgatgt aactaaatat atagtttata
     8221 ctccaacttt tcgtgattat gagactgtta ctgaaggtaa tttgcgttca atactcggat
     8281 atgttgattg tgatttgttg aagttatcga aaatactatt gaagtttaat gcggctttaa
     8341 ttcttaaatt acatcctttg cagaataaaa cagtcttaaa aaaagattta cccaaaggta
     8401 tacttgtttt tgaacaaaca tataaatatg gattgtatga tcttttgtca ttttcagatg
     8461 gaatgattac tgattatact tctacctatt ttgatttttt attggtaaat aagccagtca
     8521 tatttaattt ctacgatatt gaagaatatc gtagagtaag aggtttctca tttgagccaa
     8581 tagaattttt ttgtgcaggt gatattgttt acaattataa tgaattgata gatgctgtga
     8641 tgggacttct ggctgggaaa gatattcatg ctgaacatcg acgtcatatt tctttattga
     8701 tgaatcaatt tcaagatgat aattcaacaa agagaatatg tgacatattt ttaaatgaaa
     8761 tataataaat aaaatgaatt atgcatttgt ggtgcaggca cgtttaggtt ctacacgttt
     8821 gcctggaaaa atattgaaac ctttctatgg taatcaatcg attcttgact taatggttca
     8881 taagctttct gctatatcga atattccagt aattattgct acaacaaatt ctgttatcaa
     8941 tgaacctatt gaaaagaagg cacttgcatt aggggtaaag tgcttcagag gtgaggagaa
     9001 tgatgtttta aaacgattca ttgatgttgc tgaatatttt gatatacagg gtatattccg
     9061 aatatgttct gataatccat ttttagatgt acatgcggca aggcaattgg tcgaaatagc
     9121 aatgaaatct tgtaacgatt atataagttt tgatattgat ggtactccat caattaaaac
     9181 tcatttcggt ttttggggag aatttgtaac gcttgatgcg ctgaagcgag ttataggatt
     9241 tactgatgat ttattgtatc gtgaacatgt tactaattat atatatagtc atcctgaact
     9301 ttttaatatt caatggattt caggatctcc agtcgtgtca aaacatcata atattcgact
     9361 cacgattgat acgttagaag atttttctgt agcacagaga atatataggg atttacaaga
     9421 aaaaagagtg gaaatatcga tagaagtgat tgtagactat gttcgaagac atgcagaata
     9481 cattcaactg atgaaacaac aaataaaaaa aaattctaaa taatgaagaa tacttatatt
     9541 attggtgaaa tagggcagaa tcataatggt tctgttgact tggctaagtt gattattgaa
     9601 ttaatctcac gacctgtaca tgaggatgtt tttggtatgg atttcatgcc aatgaatgct
     9661 gttaaaatga ctaaaagaga tttatcagaa gaattggctg tttctcaaat gaatcaaata
     9721 tatgacaatc ctaattcttt tgggcgtact tatggtgaac atcgtgcttt tcttgagctt
     9781 gatgatcaag cgcattttga gatttataaa tatgctaagt cattaggatt agattttatc
     9841 gagacgttat gtgccaaagg atgtctgtct ttgcttaaac tgttcacacc ggataggcta
     9901 aaagttgcta gtcgtgattt gactaactta ccattgcttg aagcattagc agaaactcat
     9961 attcctatta tattatcgac aggaatggct ggtcaaagag aacttgacaa tgcattagat
    10021 gtgataacga gatatcatag taatatagct attctacatt gtgtatctca gtatccaact
    10081 catccaaata atttgaatct acgtacaata acatatttga agaagcatta caataagttt
    10141 gagataggtt tttctgatca tacaataggt atttctgctg ctacagctgc tgtagcgatg
    10201 ggagcggaaa ttatagaaaa gcatgtaaca attgatcggc atatgaaagg aacagaccag
    10261 cttggctctt taggtccaga tggggttaat cgtatgattc gagatattcg catagcagag
    10321 tgttggcttg gtactgaaga tctttatata gaaaaagggg tggagaagtc taagataaaa
    10381 cttgaacgtt ctattgccac tcgaaaatat attccagcag gtagtattat tcaagagtcg
    10441 gacattcatt tactgagtcc tggtgatggt tataaatgga tagataaaaa aaatgtaatt
    10501 ggtcattttg ctaaacaaga tatatcagcg aatgaaataa tatatcctga ttttattgaa
    10561 tagatatatt cctactgcaa cttgtattac ggtatagagt actgcctgct ataagctaag
    10621 tagtgattaa taaataaggg taaaatacta aaaaaatgaa agagataaag cttatactta
    10681 cagatattga tggcgtttgg actgatggcg gaatgtttta tgatc
//
