LOCUS       c00197_gnlPro..         4856 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OOGJOHKA_197.
ACCESSION   c00197_gnlPro..
VERSION     c00197_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 13:54:59
            Original ID  :: gnl|Prokka|OOGJOHKA_197
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4856
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4856
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[713:4856]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      714..4856
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4856
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4856
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..662)
                     /locus_tag="ctg197_1"
                     /transl_table=11
                     /translation="MDFRGRVTLPMIGNYLIHAASSHAGERGFGFNDMSERHTAWVLSR
                     LAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFGFARSIWAAIDVETRR
                     PTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSDLDINGHFNSVKYIEH
                     LLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQDMAICHEGKAICR"
     CDS             complement(714..1268)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg197_2"
                     /sec_met_domain="ALS_ss_C (E-value: 4.9e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(1284..2987)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg197_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     161.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVEYEYKKVDYVRSYQPEPDINKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVAVDVKVLGNAKHTIPMITALLEERR
                     RLEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             complement(3021..4856)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg197_4"
                     /sec_met_domain="ILVD_EDD (E-value: 1.3e-217, bitscore:
                     711.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEIGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKK
                     SFTPPMRQREVSKALRAYGKMVSSADKGGVRIVED"
ORIGIN
        1 gcacgacaga tcgcctttcc ctcatggcaa atagccatgt cttgcttatc gggagcggac
       61 tccgccttat gaagcgtaag cggcatacct tgtttaccct cggattggta ggcgatctcc
      121 agacggccga tctcacgggt cttgaactgg tcgatatcga acaaatccag cagatgctcg
      181 atatacttca cgctattgaa gtgaccgttg atatccaagt cgctgtattt gatcgaatac
      241 gggattccct ccgccttatt ctccgccggc atgatcttgc ccggcttctc gatcgggcac
      301 ggacgctcgt cgatatattt gcccaatgcc tctatatcca ataaggtagg acggcgggtc
      361 tccacgtcga tagccgccca aatagaacgg gcgaatccaa aggttttccc attctcatcc
      421 gccagctcaa aacaacggct ggtgaagagg cgtccgacct catcgatcca agtgtataga
      481 ttaatcttat cgaaggcggt aggatattcc ttcatctcga tagccagacg ggacaacacc
      541 caagccgtat gacgctccga catatcattg aaaccgaacc cacgctctcc ggcatggctg
      601 gaagcggcgt gaatcaaata gttaccaatc atagggagcg ttacacgtcc cctaaaatcc
      661 atcaaatacg gctccgccac gaaatgaaat aatcctactt tctccatatc ttattattgt
      721 tgcttttcat gtaactttcg ctccatatcg gccaacatat cgctcaagcg ctccaccttg
      781 ctcttcgtga tagccacacg tccggagcgg atgaattgca ggacaccgat cgtctcgctc
      841 aactcattga acaaggcttg tgtctcgtca tagtggccac tcttctccaa caccacgcag
      901 gtctcgttca tctccaagat acgagcgttg tatttacgga tcaatccctc cacggttccc
      961 atcttgatga aaagctcggt acttagctta taaagagcga tctcttgata aaccaaatcc
     1021 tcatccgtat tataataagc cttcaagata tccacacgtt tatcgatctg tttcaccacc
     1081 ttatcgatca tatcctcatc ggcgaatgtc gtgatcgtaa acttatggat gcccttgata
     1141 gcggacggag agacggacag agtctcgatg ttcagctgtc ggcgtgtaaa gataatcgtt
     1201 atctggttca aaagacctac gatattctct gaaaagataa taacggtata taatttcttt
     1261 gttgtcatag cttcatctcc tccttatttc tcgtctccca taatcatgtt tgtcacgctt
     1321 cccccggcag gaaccatcgg atataccatt ccgcaagtct ccacgttagc gaccaacacg
     1381 taagcgccgt cgtggtttag catctcagcg atagcgtcgt ccaattcctc ccgcttttca
     1441 acggcacggc cggcgatacc ataggcttta gcgatcgcca cgaaatccgg attctccata
     1501 atggtgtttg aataacgctc gtggaagaac aattcttgcc actgacgtac catacctaag
     1561 aagttattat taagaataat aatcttcacg ttcagtttct cctgcatgat ggtacccaat
     1621 tcctgaatcg tcatctgcat acccccatca ccggtaaaga agcagaccgt acggtccggg
     1681 gccccgaact ttgcgcccat agcggccggc agaccaaatc ccatcgtacc taaaccaccg
     1741 gaagtcacca cgctacgggt ttgtttatat ttgaaatagc ggacgcccat catctggttc
     1801 tgcccaacgt cggttaccaa tacagcgtcg ttaccggtcg cctcggaaac cttacggact
     1861 acctcgccca ttttcagttg gccctcggtc ggatacaatt ccttctcgat taccttatcg
     1921 tattcctctt tctcgtcccg atcgaactcg gcattccatt ccagacgtct acgttcttcc
     1981 aacaacgccg tgatcatcgg tatcgtgtgc ttggcattac ccagcacctt tacatccacg
     2041 gcaacattct tgcctatttc cgagttatcg atatccagat ggataatctt ggcttgctta
     2101 gcgtatgtct ttaaatcgcc agtcacacgg tcgtcgaaac gcataccgat agcgatcaat
     2161 acatcacact cattcgtttt ccggttcggc cctacgtttc catgcatgcc gagcattccc
     2221 ttgttcaatg ggaaatcggt tggcaacgca gataagccca ataccgtaga tccggcaggt
     2281 atatcattct tttggagaaa cgctttcaat tcctcttccg caccgcctaa caatactccc
     2341 tgcccgacca gacagaaggg tttcttcgcc tcattgatta aatcggcggc ggccttgata
     2401 cgatccttat tgatatccgg ctccggttga taactacgta cgtaatcgac cttcttatat
     2461 tcatattcca ccaaccctac ttgcgcgtcc ttcgctaaat ccagcacaac tggacccgga
     2521 cggcctgtag aagcgatata aaaagcacga gaaacagccc atgcgatctc ctccggcttg
     2581 cggatttgat aagcccattt cgtgatcggt tgcgtgatgc caatcacgtc gacttcctga
     2641 aaagcatcgg ttcccaacaa cggcgagggt acttgaccgg cgattacgac cattggcgta
     2701 ctatccatca gcgcgtcagc gatacccgtg atggtattcg tagcgcccgg gccggaagta
     2761 accaacgtca ctcctacctt gccggataca cgggcatatc cttgagccgc atgggtagcg
     2821 ccttgctcgt ggcgcaccaa tacatgcctc aactggtccc tataatcata taaactgtcg
     2881 taaataggta tcgcctgtcc gccgggataa ccgaagatag tatctactcc ttcagcaatc
     2941 aacgctttca gcaaagcttc cgaaccggtt atcttttgtt tctccataag aaataacgtg
     3001 tttaatgtat attattggct ttaatcttca acaatcctta cacctccctt atcggcggag
     3061 ctaaccatct tcccgtacgc tctcaacgct ttcgagacct cacgctgacg catcggcggc
     3121 gtaaaggatt tctttccacg cgcctcttcc gctttacggc gctcggccaa ctcctcgtcg
     3181 ctcagccgca cgttgatgga acgttccggg atattgatct cgatgatatc cccgtctctc
     3241 accagtccga tagcgccacc ggaagcggcc tcaggagaga tatgcccgat agaaagaccg
     3301 gacgtaccgc cactgaaacg accatccgtg atcaaggcgc actccttacc taagtgacgg
     3361 ctctttatat aagaggtagg atataacatc tcttgcattc ccggccctcc tttcggaccc
     3421 tcatacgtga tgacgaccac atcgcctgaa acgaccttgc ctcctaaaat gccctcgcaa
     3481 gcggcatcct gtgaatcgaa gactttcgcc gggccggaga atttccaaat actctcatcc
     3541 acgccggcgg tttttacgac acatccgtcc aaggcgatat tccctctcaa aacagccaag
     3601 ccgccatcct tggaataagc gtgctccacg tcacggatac aaccttcggc acgatccgta
     3661 tctaattcct tataataaga ttcttgggaa cccatctgga tactgaaccg atgagcggga
     3721 gcgctcttgt atttacggat cgcctcctcc gttacgttcg gggaagtgac ggcgtattta
     3781 tcaacagcct cggccaaggt caggccgtcc gcacgtctcg tgctgccatc cacaagcccg
     3841 gctttcatca actcgttcat gataccgagg attccaccgg cacggtttac gtcttgtaca
     3901 tgataagtgt gcgtattcgg ggctacctta cacaggcaag gagtcttgcg ggataacata
     3961 tcgatatcct ccatatgaaa atcggcgccg gcttcttgtg ccacggccaa taagtgaagc
     4021 actgtattgg tagacccccc catggcgata tccagcgaca tggcgttcaa gaaagcctga
     4081 cgggtagcga tgttgcgagg taacacggaa tcatccccgt cacgatagta tttgtaagcg
     4141 ttctctacga tttgcttagc cgcgtcacgg aaaagttgga tacggttctt atgggtagcc
     4201 acgatcgtcc cgttacccgg aagcgccaga ccgatcgcct cgttcaagca gttcatagag
     4261 ttagcggtaa acataccgga acaacaaccg caacccggac acgcatggcg ttccacctgc
     4321 tcgatacgct catcgcttac cgatgtatcg gcagactcaa tcatcgcgtc gatcaaatca
     4381 agatggcggc catccagctc acctgcctcc atcgggccac cggacacgaa caccgtcggg
     4441 atatttaatc gcatggaagc cataagcata cccggcgtga tcttatcgca attgctgatg
     4501 caaaccatag cgtccgcctt atgggcattt accatatatt ccacgctgtc cgcgataatg
     4561 tcgcgtgaag gaagcgagta aagcatccca tcgtgcccca tagcgatacc gtcgtcgata
     4621 gcgatcgtat taaattcagc ggcgaaacaa ccttgtttct cgatctcggc cttgaccagt
     4681 tgcccgatct catgcaaatg cgtatgcccc ggcacgaact gggtaaatga atttacgata
     4741 gcgataatag gcttgccgaa ctgttcctct ttcatcccgt tggcacgcca tagcgcacgg
     4801 gctccggcca tcctacgacc ttcggtgcta aatgagcttc ttaacggatt cttcat
//
