LOCUS       c00123_gnlPro..         8999 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MPAGDJAE_123.
ACCESSION   c00123_gnlPro..
VERSION     c00123_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 13:19:36
            Original ID  :: gnl|Prokka|MPAGDJAE_123
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8999
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1443
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_1"
                     /sec_met_domain="ILVD_EDD (E-value: 4e-177, bitscore:
                     578.7, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLIDAM
                     IKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATHEN
                     RKKLFEDAAKLIVANAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLHLL
                     AVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGGLV
                     DTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELDTD
                     RATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDAAC
                     DGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTS
                     GLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNREVS
                     KALKAYASMVSSADKGAVRLID"
     protocluster    1..8999
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:5722]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..5722
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8999
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8999
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1535..3286
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.9e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             3319..3879
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_3"
                     /sec_met_domain="ALS_ss_C (E-value: 4.2e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             3876..4628
                     /locus_tag="ctg123_4"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYIAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             4679..5722
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_5"
                     /sec_met_domain="IlvN (E-value: 2.7e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.4e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIIMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(5784..7697)
                     /locus_tag="ctg123_6"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQLLLRMEYEYEKEEFKRQTENMG
                     VARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGTSKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NAELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCHEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     IGGSRILEEKIDFGIISPYKAQVQYLRSKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             7812..8999
                     /locus_tag="ctg123_7"
                     /transl_table=11
                     /translation="MVYDLTMLKTFYAAYSEKIERVRNVLRRPMTLAEKILYAHLYDGD
                     KVKNYRRGEDYVNFRPDRVAMQDATAQMALLQFMNAGREQVAVPSTVHCDHLIQAYKGA
                     KEDVATATKTNEEVYNFLRDVSSRYGIGFWQPGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKMPRLIGVHLKGKLSGWVAPKDVILKLAGI
                     LTVKGGTNAIIEYFGPGTASLSATGKATICNMGAEVGATTSLFPYDERMGTYLKATGRE
                     EVAKMAASVAADLRADDEVLANPEKYYDRIIEIDLSLLEPYINGPFTPDAATPISKFAE
                     VVITNNYPRRMEVGLIGSCTNSSYQDLSRAASLARQVKEKNLKVASPLIVNPGSEQ"
ORIGIN
        1 agtaactgtg acaagattac tccggggatg ttgatggcgg ctatgaggct gaatataccg
       61 actgtgtttg tttcaggcgg tccgatggaa gccggggaat ggaacggaca acatttggat
      121 ttgattgatg ctatgattaa atctgctgat gaaagtgtgg gcgataaaga ggtggcacag
      181 attgagcaac atgcctgccc cacttgcgga tgctgctcag gcatgtttac cgctaattcc
      241 atgaattgcc tgaatgaagc gattggattg gcactgcccg gtaacggcac gattgtagcc
      301 actcacgaaa atcgcaagaa actatttgag gatgcagcta agttgattgt agcgaatgcc
      361 tttagatatt atgaagaagg ggatgagagt gtactcccgc gcagtattgc tacccgcgag
      421 gcatttttga atgccatgac gctggatatt gcgatgggcg gttccactaa tacggtactt
      481 catttgttgg ctgtggctca cgaagccgga gcggatttta agatggacga tattgacatg
      541 ctctcccgca agaccccctg cttatgcaag gtggctccca atacccaaaa gtatcatgta
      601 caagacgtta accgtgccgg tggcatcatt gccatcatgg atgagcttgc caagggcgga
      661 ttggtcgata cgaatgtccg ccgtgtggat ggaatgacgt tggcagaggc aatcgaccgg
      721 tatagtatta ccagctctaa tgtatgtaaa gaggcaatca agaaatactc cagtgcggca
      781 gccggaaagt tcaatctggt actcggctca caaaatgcgt cttataagga actcgatacg
      841 gaccgtgcga ccggttgtat ccgtgatttg gaacatgcat acagcaagga tggcggtctg
      901 gcggttttga agggaaatat agctcaggac ggttgcgttg tcaagactgc cggtgtagac
      961 gagagtatct ggaaatttac ggggccagcg aaagtcttcg actcacaaga tgcggcttgt
     1021 gacggtattc tgggtggaaa ggtggtcagt ggagacgtcg tcgtcatcac tcacgaaggg
     1081 ccgaaaggtg gaccgggtat gcaagagatg ctttatccta cttcttatat caaatcccgc
     1141 catctgggta aggagtgtgc attgattacc gacgggcgtt ttagtggcgg tacttccgga
     1201 ctaagtatcg gacatgtttc tcccgaagcg gctgccggtg gtaatatcgg caagattaag
     1261 gatggggaca ttatcgaaat tgatataccg aaccgttcta tcaatgtgaa gttgacggat
     1321 gaagagcttg cagcacgccc tatgactccg gtaacccgca accgtgaagt ctccaaagca
     1381 ttgaaagcat atgccagtat ggtgagttcc gctgacaaag gggctgtgag gctgattgat
     1441 taaaagcccc cctttccgaa agcgagggga ggagagaatg aaacaaattt ttcaagctac
     1501 tattgagctt ttaaatataa tgaatagata aagtatggct gataataata aaaagagtaa
     1561 cttttcctcc ctctcccaag gagagggtcg gggtgaggct ctaataacag gcgcagaagc
     1621 attgatgcgc tctctggagc atcagggagt aaagactatt ttcggttatc cgggagggag
     1681 catcatgccg gtattcgatg ccttatacga ccatcggaag gaattgaacc acatcttggt
     1741 tcgtcatgaa caaggagcaa cccatgcggc acaaggcttt gcacgtgtat caggcgaggt
     1801 tggcgtttgt ctggttacca gtggaccggg tgctaccaat actatcacgg gcattgcaga
     1861 tgccatgatt gacagtacgc ctatcgttgt cattgccggc caggtaggga cgaacttctt
     1921 gggtacggat gcatttcagg aagtggactt ggtaggcatt actcagccta tcacgaaatg
     1981 gagttaccag attcgtcgtg cagaagatgt ggcctgggca gtggcacgtg ctttctatgt
     2041 ggcaaagagc ggacgtccgg gaccggtcgt gctggatttt gctaaaaacg cccaagtgga
     2101 gaaaacagaa tatgcgccta ctaaggtgga ctatgtccgt agctatcttc ccgttcccga
     2161 aatggagccg gaggccatac ggaaggctgc tgaattaata aatggtgcgg aacggccttt
     2221 ggtgctggta ggacaaggcg tggagctggg agaagcccag caagagcttc gtgctttcat
     2281 tgagaaagcc ggaatgcctg ccggatgcac tttattggga ctttccgcat tacctacgaa
     2341 ccatccgttg aacaaaggaa tgcttggtat gcacggtaac ctggggccca atatcaatac
     2401 caataaatgt gatgtcctta tcgccgtagg catgcgcttt gatgaccgtg tgacgggtaa
     2461 attggaaaca tatgccaagc aggcgaagat tatccacttt gatattgacc ctgccgaaat
     2521 agataagaat gtaaagactg atgttgctgt cctgggagat tgcaaagaga cactggctgc
     2581 cgttacccaa ttgctggaac ccgccaacca tcaggaatgg attgacagtt tccggcaata
     2641 cgaggaagtg gaagaggaaa aggtaatccg tccggaatta catccggcag gaaaagcgct
     2701 aagcatgggt gaggtggtgc gtgctgtgag tgaggctacc cataacgagg cgatattggt
     2761 gactgatgtc ggccagaatc agatgatgtc cgcccgttat ttcaaataca gcaaggaacg
     2821 tagcattgtt acttccggtg gcctgggtac tatgggcttc ggccttccgg cagctatcgg
     2881 tgccactttt ggacgtccgg accgcacggt atgcgtattc atgggagacg gcggcttgca
     2941 gatgaacctg caggaactgg gtaccatcat ggaacaaaag gctccggtga agatgattct
     3001 gttgaacaat aacttcttgg gcaatgttcg tcaatggcag gcgatgttct tcaatcgtcg
     3061 ttattcgttt actccgatga tgaatccgga ttatatgaag attgcttcgg catatgatat
     3121 tcctgcacgc agggtaatga cccgcgagga gctggcaaaa gcgattgacg agatgatagc
     3181 gactgacgga ccgttcctgc tcgaagcttg tgtggaggaa gaaggaaatg taatgccgat
     3241 gacacctccg ggcggttcgg tcaatcagat gttgttggaa tgctgaagtc atgcgaaatt
     3301 aaagaactta ctctatctat ggataaaaaa ctatatacaa tcattgttca ttcggaaaac
     3361 tttgccggtt tgctgaatca ggtgacggct gtgtttaccc gccggcagat aaacatcgag
     3421 agtttgaatg tatcggcctc ctccatcaag ggggtacata aatataccat taccgcttgg
     3481 acggacaagg ataccattga aaaggtgacc aagcagatta ccaagaaaat agatgtgctg
     3541 caagcccatt atttcacgga tgatgaaatc tatcagcacg agattgccct ttataaaata
     3601 acgaccccta cgctggaaga aaaaccggag gtgtccaaag taatccgtaa gtacaatgcc
     3661 cgtattgtgg aggtgaatgc tgtatttgcc attgttgaga agaatggcat gagtgaggaa
     3721 ataaccaatc tttatgagga gttgcgccag ttggattgcg tacttcagtt cgtccgttcg
     3781 ggtcgcgtag ccattacgac cagctgcttt gagcgtgtca atgaatatct ggcggaccgt
     3841 gaagcaaaat atcgtcaaag taaacaccag gaatcatgat gagcgagaac aataaaatag
     3901 gtacctacaa gtttgttgcc gaaccgtttc atgtcgactt taccggacgg ctgacaatgg
     3961 gagtattggg caaccatttg ttgaattgtg cgggtttcca tgccagcgac cgcggttttg
     4021 gcatcgcgac tctaaacgag gacaattata cttgggtatt gtcccgtctg gctgtcgaac
     4081 tggatgaaat gccttatcag tacgaagatt tctccattca gacttgggtg gagaatgtct
     4141 atcgcctttt tacagaccgt aatttcgcta tcatcgataa ggagggtaag aagattgggt
     4201 atgcacgttc cgtttgggcg atgattagca tgaatacccg taagccggca gatttgctgg
     4261 ctcttcatag tggcagcatt gtagattatg tttgcgatga gccttgcccg atagaaaaac
     4321 cttcgcggat aaaggtggcc tcaaaggaac cggttgctgc tttggtagcc aaatacagtg
     4381 atattgacat taacgggcat gtgaacagca tccgttacat cgagcatatc cttgatttgt
     4441 tcccgataga gatgtataag gagaagcgca tccgtcgttt tgaaatggca tatatagccg
     4501 aaagctatta tggggatgag ttgactttgt tcatggatga tgccggtgag ggcgtttacg
     4561 atgtggaggt gaaaaagaat ggcagcgaag tggtctgtcg ctctaaagtg atatttacag
     4621 agaaataaat aaatttatca acgttggcgt aagccacaaa taaaaattaa aacaaaaaat
     4681 ggcacaattg aattttggcg gtgttattga gaatgtaatg acccgcgaag aatttccttt
     4741 ggaaaaagca cgtgagattt tgaaagatga aacaattgca gtaatcggtt atggcgtaca
     4801 aggcccgggc caggcttgca acttgcgtga taacggtttc aatgtgattg taggacaacg
     4861 tccgggtaag acatacgaaa aggctgtggc tgacggatgg gtaccgggtg agactttgtt
     4921 cggcatcgaa gaggcttgtc agaaaggtac tatcatcatg tgtctgttgt ctgacgcagc
     4981 tgtaatgtct gtatggccga ctatcaaacc ttatttgact cccggaaagg ctctttactt
     5041 ctctcatggt tttgctatta cctggaacga ccgtaccggc gtggttcctc ctaaagatat
     5101 tgatgttatt atggttgctc ccaaaggttc cggtacttca cttcgtacca tgttcctcga
     5161 agggcgtggc ttgaactcat catatgccgt ctatcaggat gctacgggta aggcttttga
     5221 caagacgatt gcactgggta tcggtatcgg ttcgggatat ttgttcgaga caactttcat
     5281 ccgcgaagcc acttccgact tgaccggtga acgcggttca ttgatgggtg ctatccaggg
     5341 attgctgttg gctcagtatg aagtattgcg cgaaaacggt cacactcctt ctgaagcatt
     5401 caatgaaact gtggaagagt tgactcaatc tttgatgcca ttgtttgcca agaacggtat
     5461 ggactggatg tatgccaact gttctactac ggcacagcgt ggtgcgctgg attggatgac
     5521 cccgttccat gatgccatca agccggttgt acagaaattg tatgcaagcg tgaagtcggg
     5581 taacgaagct cagatttcta tcgacagcaa ctccaaaccc gattatcgtg agaagctgaa
     5641 tgcagaattg aaagccttgc gtgaaagcga aatgtggcag acagctgtta cagttcgtaa
     5701 acttcgtccg gaaaacaatt aatcagcttt atataaatag gtgaaatacc ctcttcggtg
     5761 ttaccggagg gggtatttct ttattattga ttccctatat tttgaataaa ctccaatagc
     5821 ttccggtaaa aaccgtgatg tttcagcgtc tctgcctctc ccaatatcac cagcttcata
     5881 cgtgcccggg tgatggctac attcattctc cttaaatcat tcaggaatcc tatctgtcct
     5941 tcttcgttgg cacggacaag gctgatgaag ataacatcgc gctcttgccc ttggaagcca
     6001 tccaccgtat ttacagtgaa caagctgcga taaggcttga gtgaagcgtc tgcctttatc
     6061 ttgctgcgga gatattgcac ttgtgccttg taaggggaga tgatgccgaa gtctattttt
     6121 tcttccagaa tgcggctgcc accgatacgg ttgatgtaga ttttcagttc tgataggagc
     6181 aggtccgctt ccgccttatt aatgcgtccg aaagtctctc ccacaaattc ttctttgaaa
     6241 tccatttcgg aggtgtcaat ccagtggatg ggggtatccc agtccaggat gccccggtaa
     6301 cgcacttcgg gagcggcttc caactcgcca ttataaaacc attgggaagg aaatttcatg
     6361 atttcctcgt gcatgcggta ttgcactttc agcaaagaga caacggcagg tttgttggac
     6421 accactttct ccatcaatgt tcgttccaga cctccacggg cggcttcgtg gcattttatg
     6481 gtgggcggaa gttggcagtg gtcacccgcc aataccacgc ggtctgcttt tcggatagct
     6541 atccagcagg cagcttctaa ggcctgggct gcttcatcaa tgaaaagggt gccgaaacgg
     6601 cgtccgttca gcagccggtg attgctgctt actagcgtgg aggctatgac atgtgcccca
     6661 tcaaaaagct ctgcattgat ttgtatttcc aatgcggtgg cgcggtcgcg caggcggctc
     6721 atacggctgc gtactccttc gcgttcgtca tagctgccac ggcgggcacg gctgcccagt
     6781 tcacggagat ttttccggat gctccacagt tccggataaa gcggatggtt ctcgaaacga
     6841 cgctcgtagg taaaggaaag catcttgtcg ttgacacggg tcggattgcc gatacgcagg
     6901 acattgacgc cacggtccac aagtttttcc gaaatccagt cgacggcagt attgctttgg
     6961 gcacatacta gtacctgcgg ttcccgatgc agggtttcgt agatggcttc cactaaggtg
     7021 gtcgtttttc cggttcccgg aggaccatgt acaatggcca cgtcgcgggc acacagcact
     7081 ttgtttacag ctgtctcctg cgtggagttc agccagggaa accgtacggg gtagagctct
     7141 cggaaaccgg ctttcgaggt tcccagcaat atgtcccgca attcggccag gcggttgcct
     7201 ttggagcgta acgtatcttc caaggcttcg aacatggtcc gataggatgt ttcgtcgaaa
     7261 taaagttgca cgccgaggtt gtccgtttcc tgcacttcca taacggcacc ggctccgggc
     7321 attatcgcta ccatccgtgt ctcgtcggca tagcttacgg tagcggtgaa gttcatatag
     7381 gttatttttc catcggcaga ctggcggaaa aaacatacgg gacggccgaa ctcaaaatta
     7441 tgttctatat cggtattttc tgtgtgtgta atttctatta ctaattgatt cagtgaatta
     7501 tagtaacttc gtcccggagt ggcaggatac cagcaaagtc cccgtttcac tttccgggca
     7561 actcccatgt tttcggtttg gcgtttgaat tcctcttttt cgtattcgta ttccatgcgc
     7621 agcaaaagtt gttgctgctg gaggtgaata ataggactat ttgaatcttg ttccttcatg
     7681 gttgcaaagg taatcattct tcgcttccga cagaaaaaat gctttatttt gttaaactat
     7741 tcagcctttt tatttgttta tgatattaat ttgtaatctt tacaataatg aaaaactaaa
     7801 aaatagtggt tatggtatat gatttaacga tgctcaaaac gttttatgct gcttattcgg
     7861 agaagataga acgcgtacgg aacgtactgc ggcgtccgat gactttagca gagaaaattt
     7921 tgtatgctca tttgtatgat ggggataaag tgaagaacta cagacgggga gaagactatg
     7981 tgaatttccg tcccgaccgt gtggccatgc aggatgcaac ggctcaaatg gccttattgc
     8041 aatttatgaa tgcaggccgt gagcaggttg ccgtgccttc cactgtgcat tgtgaccatt
     8101 tgattcaagc atataaaggt gcaaaagaag atgttgcgac tgctacgaag accaacgagg
     8161 aggtctataa ttttctccgt gatgtttctt cccgctatgg tataggtttt tggcagccgg
     8221 gggcaggcat tattcaccag gtggtattgg agaactacgc atttccgggt ggaatgatgg
     8281 taggcacgga ctctcatacg cccaatgccg gaggtttggg catggtggcc attggtgtgg
     8341 gtggtgccga tgcggtggat gtgatgaccg gcatggaatg ggaactgaaa atgccgcgtc
     8401 tgataggcgt acacttgaag ggtaaattga gtggctgggt agctcccaaa gacgttattc
     8461 tgaagttggc gggtattctt actgtaaaag ggggaaccaa tgccatcatt gaatattttg
     8521 gaccgggaac cgcttcattg tctgccactg gaaaggctac catctgcaat atgggggcag
     8581 aggtgggggc gactacctcc cttttccctt acgatgagcg catgggtacc tacttgaagg
     8641 ctaccggacg tgaagaagtg gcaaaaatgg ctgcttccgt agctgccgac cttcgcgccg
     8701 acgacgaagt gctggcaaat ccggaaaaat attacgaccg catcattgaa atagacctct
     8761 cgctattgga accgtatatc aacgggccct ttacgccgga tgcagcaaca ccgatatcga
     8821 aatttgccga ggtagtgata accaataact atccccgccg gatggaagtc ggcctgatag
     8881 ggtcgtgcac caattcgtcc tatcaggatt tgagccgcgc agcctccctt gcccggcagg
     8941 taaaggaaaa gaatctgaag gttgcttccc cgctgattgt caaccccggt tcggagcag
//
