LOCUS       c00025_gnlPro..        16262 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|COIINBLA_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 13:27:17
            Original ID  :: gnl|Prokka|COIINBLA_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16262
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16262
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4269:7848](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4270..7848
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16262
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16262
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(3..740)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_1"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 1.2e-43,
                     bitscore: 138.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLHKIAVIGAGSWGTALSMVLATRECEVVLWTPEEAQARQLAE
                     TRRSPVLSKTALPLAPNIHPTCDLGQVKDAELIVVVVPSVAMRSVTQRLRSLPVQPDAV
                     IVSCTKGIEQGTHKRMTEILQEYLPSNPIGVLSGPNHAEDICLGLPSASLIGFEDPKYA
                     DWVQQIFASKTFRVYSATDIIGMQLGGTIKNVFAIGAGLCEGLNLGDNAQAALLTRGLA
                     EMTRIGVASGGRRETFMGLSGVGD"
     CDS             complement(745..1389)
                     /locus_tag="ctg25_2"
                     /transl_table=11
                     /translation="MIAWIVFYYLIGAIPFGYLAGRIRGIDLRQQGSRNIGATNAWRVL
                     GWKWGLSVFILDFLKGFIPVFGALNWLPFLTGDAGGWDFNVLVVLSCFAVILGHTYTCF
                     LGFRGGKGVATTAGVLFALNPVVACVALASWLVVMGISGIVSLASLVAAVVMIAAGWWI
                     YPLCQDGDVSPQILYVAFFTVVGALVILKHRSNIARLLNGTEHSFYSKKSK"
     CDS             complement(1642..2427)
                     /locus_tag="ctg25_3"
                     /transl_table=11
                     /translation="MVPRTPDILDCASAQWIGKRREQEDVVKSLPAAGGMLGIVCDGMG
                     GHLRGDCASCVVAQEFAAVFAESGIEDIPERLTAALHAANRALSAIQKEPEESGTTLLA
                     VFIRDHFLWWISVGDSPLYLWSGADSFRMDRLNEDHSMRPIADSLYRKGKMSLQGALRQ
                     RCILRSAVMGGPMELVDISAMPLLLHPGDAVLACSDGLQVWSELLREPSFLALQKARDC
                     SSRELVGIIMEQVKDMLEPQQDNASVWAAVMRKPCEGGK"
     CDS             complement(2445..3926)
                     /locus_tag="ctg25_4"
                     /transl_table=11
                     /translation="MSEQQQAHPTTTESELIAVRRDKLAKIRELGIDPYGARFDVTTTP
                     AGLKADFQEDKQVAVAGRLLAIRDMGKSQFFVIGDVRGKIQGFLHKNEVDETTWKLWKL
                     LDRGDWVGIRGTTFLTRTGEPTVKVSGLTILSKSLRPLPDKWHGLADKEVTYRKRHLDL
                     ISNEESASLFVTRSLMIAEIRRFLQERGYLEVETPMLQDVAGGAAAKPFETYHNALDMP
                     LTLRIAPELFLKRLMVGGFTKIFELNRSFRNEGIDRRHNPEFTMLEAYCACGDFETMAN
                     MVEELICHLAEKFCGGLQIDHKDAEGNVLYTIDLSRPWRRADYQDLIRGVAGEDWFDIS
                     PEARRARCEELGVEISPDMKDVDVSQQVYEKLVEEKTMNPCFVTHVAKDLVPLAKLNRE
                     NPDVVDVYELVINGQEISPGYSELNDPDVQKERLEHQAAGETQRVDYDFIETLEYGMPS
                     AGGIGIGIDRVVMMLTGASSIRDVLLFPQLKRKDS"
     CDS             4270..7848
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_5"
                     /sec_met_domain="PFOR_II (E-value: 4.3e-18, bitscore: 55.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.3e-79, bitscore: 255.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.2e-32, bitscore: 103.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.5e-12, bitscore:
                     36.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 7.9e-14, bitscore: 42.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 8.4e-11, bitscore: 31.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-06, bitscore: 17.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.2e-26, bitscore: 81.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQTTVTYSTIDANEAVASVAYRFSEVIAIYPITPSSPMGESAE
                     SWAAVNRKNLWGTVPSVVEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKI
                     AGELTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAADFAAISHAA
                     TLESRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPVLRGT
                     AQNPDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVIILMG
                     SGAEAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTKEPGS
                     QGEPLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNLALDT
                     PKNHFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKIIGQHT
                     NLYVQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDFLKNA
                     ANGATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRINMIMQ
                     TCFFKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTTGKTV
                     NGHAIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNLALDL
                     PEWDPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKFVIQI
                     SPNDCTGCTLCADVCPAKSKTDPTHKALTMVPAGKIHDKEEANWNFFLSLPDVDRTKVR
                     TDNIRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGNLPTT
                     PWSHDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELVDRIL
                     ANPQKDEADIAQQRENIEELKKKIAGKPEYARLLTLADKLVRKSVWILGGDGWAYDIGY
                     GGLDHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATTGKPGVKKDLGLMAM
                     TYGNVYVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAKGLQQQKAWV
                     DSGRVLLYRYNPDLARQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTNKEGFEKLLE
                     EAQKDVWHRWNLYQSIAGMGADKPAE"
     CDS             complement(8314..8751)
                     /locus_tag="ctg25_6"
                     /transl_table=11
                     /translation="MNKIIIANYRETEPQVISREGNSFAVKPVIREADAGKCAASFVEV
                     EPGRYAYGYHYHEVNEEVFYIIRGHAVVRTPEGEKNLEEGDAIAFPASPEGAHVIRNGS
                     ATEKLVYLDVGTRLTPDVVHFPDTASGMVYSSSGVHHFRES"
     CDS             8876..9196
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MTYYNSSCPVETTLQLISSRWKVLILRDLLEGTRRFGELRKSIGP
                     VTQKVLTANLRSMEKDGLLTRKVYAEVPPRVEYTLTELGRSLRPVLASMAEWGSKYQRE
                     NR"
     CDS             complement(9278..11416)
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="MRMRCLFFPLCSAIALTSFVQAQSLERHPLYEPALVSVGTPGDAG
                     NLFAGAKVTASGHYGSDRPELAVDGQTNNAGKYWGCEGIPVWLQIDMGKPRTLSSLHVW
                     PYWEGGRIYKYKIEGSEDGKNWKMLADQSSNSIAATPEGVPFKFNPQTVRYVKITFLGN
                     SAGNEKGGHLVEIKGYGPDAALSLQAAAVKDYDRIPYNGAPGQEMLQDAVRLSGWRGER
                     AGGQIAVWSSQAQPQLSASCAGVKNAAGQIIPVRTAMIRYTRGGNRLISDIIGSENSCD
                     LQAGGVRPVWVEVNIPPSAKPGVYKGKVVVSAESGSPVSVPVILEVAPESLPAPAHWQV
                     HLDLWQHPQAVARWHDVEPWSPEHFALMKPVMKRLADAGQKAITCSLIDEAWNAQTYDW
                     FPPMIEWVKGKNGTMRWNYANFDKWVSFMMNEVGVKGQISCYTMIPWNMKIRYLDEATG
                     KYKFLDLKPNDPSYEAIWGPFLTDFRKHVKSKGWLGKTCIGLDERPDAMVRAAKNVLDK
                     YAPEFKIVSAVNRPTAMTRDVYDVSPVIDHAGTVTGDLLAQRKKEGKKTTFYVCVHPKK
                     PNTFTISPLAEAEWLPLFAAANHLDGFLRWAYNSWNRNPFEKTDFGNWPAGDCYLVYPG
                     NLSSLRFEKLRDGLEEFEKVNILRARAAKNPKAKAAVARMDEELSKLFTVEKSRGDSHE
                     EDVRKAREIIRKTTEISR"
     CDS             complement(11464..12231)
                     /locus_tag="ctg25_9"
                     /transl_table=11
                     /translation="VLAKRIIPCLDVTDGRVVKGTNFINLRDAGDPVECARAYDAQQAD
                     ELVFLDITASSDGRATMADVVRRTAACCFMPLTVGGGIRSVKDMREMLLAGADKVSLNT
                     AAINRPELINEGAAAFGSQCIVVAIDAKRQASGKWGVSTHGGRKFVGLDAVEWAVEAER
                     RGAGEILLTSMDADGAKTGYDIELTRAVSSAVRIPVIASGGAGNLDHMVDVLVEGKADA
                     VLAASIFHFGEYTVPEAKAYFASRGIPVRPLAE"
     CDS             12291..12491
                     /locus_tag="ctg25_10"
                     /transl_table=11
                     /translation="MPFNKHVPFLTKALFGSVSIPHIHGKRNLLKFINITIPLTFRPTL
                     HRHEETQCGICPFPARMHKTA"
     CDS             12545..14293
                     /locus_tag="ctg25_11"
                     /transl_table=11
                     /translation="MTTTRSGFTKLAAVCIAILLGAVVWELGWPLTRAEHEWSRLIAAV
                     ATLGHLTGILGSYFRKEINRPSLRLLIFQIISCLMIFLLIAREQQEAGYMRFTELSRLV
                     ITAGLIAIPTLMSLTRIFEWLVGKQKKGRPLMAPAMQFVASLGVVILAGTGLLLLPNST
                     YPGITLSFTDALFTSTSAVCVTGLNAVDFAHTFTPLGEMFTLALIQIGGFGIMTFAYFV
                     AMVAGQGFSLRDRVLLTDLLDEDNLGAVVSFITTIVVSTLFIELCGAVLLYFSWEGKDI
                     NLMGEPLWWHSLFHSVSAFCNAGFSTFPMNLMEPGIRLCYSGQAVIMALIVCGGLGFGI
                     YKEINSRLANRFFSKHRRLHMQWTPYFKLVMISTGILLAGGALAIFAVSSPHAAEPLGE
                     HLWICLFDSVTARTAGFNISDYGRYLPAASLIMCGLMMVGGSPGGTAGGMRTTTCAIAG
                     AEILRILRGRDHVEFFRRRIDQRTVARCVITVVVSCAWIGCFTVLICALEPSMSSLDIF
                     FENCSAFATVGVSRGITPDLSGPSKYLLIVNMLAGRVGLFAFLIALAGTPTPRHYRYPS
                     VKIPLT"
     CDS             14304..15008
                     /locus_tag="ctg25_12"
                     /transl_table=11
                     /translation="MRYTVIGLGQFGQELCTELSARNIEVVAVASTDEELEQIKDLVTY
                     AVVTDYTNPAALRELELDDQSAVIVAIGDSFEENLLVVTHLQKMGVRYIYARVMSPVHE
                     HILSQMNVYALINLSRVASKQLASQLESPEFLRVSPMDENHSIVEIAVPRIWVGKRLRD
                     VGLRTEHHLNLLTIRRGEAQTPQGRREILSIPRIPVIGTPSPDLVFEDHDILVLFGKET
                     NLIEFAQLSKGL"
     CDS             complement(15101..16261)
                     /locus_tag="ctg25_13"
                     /transl_table=11
                     /translation="PKDLRVFLQPISQKAAYFAELRHGLEPDGPLAGKLAEFVEVETGK
                     FCAPSFFDMNRLPAELVTKIWVCDDEGEELAMGTDVAELNNRLGKKLSRRFQETAEDIV
                     SVTGMKEWSCGDLEYTVDVAGRPGYVALVDEGASVGVRVFEDELSAAESHREGCLRFMR
                     LRQTDQLNHLRRKFPLKLEGKLSLHMLGREPSTNAEDLVDVAAEIAMGRPLPRTAEQFA
                     AAEMNLRQNLFDAAHNVADIWELVAGTEHAVRDFTALQKGVRHTERITADLQRQLDWLL
                     RPRFLWAHGAERLPDLKRYMQGIAERIRRIGQQPLARELERLDLFERVYFPWHQVLKEH
                     AGDLRWMQYGYLLEEYRLAVFAPAISVKGRVSEKRLVASFEALSSQ"
ORIGIN
        1 aaatcgccta ctccggaaag gcccatgaag gtttccctgc ggcctccgct ggccacgccg
       61 atgcgcgtca tttccgccag gccgcgggtc agcaaagcgg cctgggcgtt atcccccagg
      121 ttcagccctt cgcataagcc ggccccgatg gcaaagacgt tcttaatggt tccgcccagc
      181 tgcatgccga taatgtccgt agcggaataa acacggaagg ttttggatgc aaatatctgc
      241 tgcacccaat ccgcatactt cggatcttca aatccaatca gggaggcgga cggaaggccc
      301 aggcagatat cttccgcatg attgggaccg gaaagcacgc ctatggggtt ggagggcaga
      361 tattcctgaa ggatttccgt cattctttta tgggttccct gttcaatgcc cttggtgcag
      421 gagacgatga cggcatccgg ctgcaccggc aggctgcgca gccgctgggt cacggaacgc
      481 atggccacgg aaggtaccac tactacaatg agttccgcat ccttcacctg gcccaggtcg
      541 caagtaggat ggatattggg ggccagggga agggcggttt tcgaaaggac ggggctgcgt
      601 cttgtttcgg caagctgcct ggcctgagcc tcttccggcg tccacaggac gacttcacat
      661 tcccgggtcg ccagaaccat ggaaagggcc gtgccccagg aaccggctcc aatgactgct
      721 attttatgta accgattcat catcttactt ggactttttg gaatagaagg agtgctccgt
      781 tccgttgaga agccttgcga tattggaacg gtgcttgaga atcaccagtg cgcctaccac
      841 cgtgaaaaag gcgacgtaaa gtatctgggg ggagacatcc ccgtcctggc aaagcggata
      901 aatccaccat ccggcggcga tcatcaccac agcggccacc aggctggcca gggacacgat
      961 gccggaaatt cccataacca ccagccaaga agccagagcc acgcaagcca ccaccggatt
     1021 gagggcaaat aaaacccccg cggttgtcgc tacgcctttt cctcccctga atcccaggaa
     1081 acaggtgtaa gtatgaccga gtataacagc gaaacaggag agaactacca agacattgaa
     1141 atcccagccg cccgcatccc ccgtcaggaa cggcagccag ttcaaggcgc cgaacacagg
     1201 gatgaacccc tttaagaagt ccagaatgaa aacggaaagg ccccacttcc agcccagtac
     1261 gcgccacgca ttggtagcgc ctatgttgcg ggaaccctgc tgcctcaggt caatccctct
     1321 gattctgccg gcaaggtagc cgaacggaat cgctccgatc aggtaataga aaactatcca
     1381 ggcaatcatg ttgtgcggag tgcattttaa tcccccgccg gtcaaatgac aatggggaaa
     1441 tcacctccgg cccggttctt tccggagggg ttgctcccgt aaaagaacac catgcctgac
     1501 ggcctcctcc agatcctcat tttcagggtt ctccgtgccc cggtctgcgg aaaagccctg
     1561 tttaaggcgc aataagaaca gcgcgaacat tttcccgccc gcacagaacc atgctcccgc
     1621 acttccttcg ccggaataag attatttacc gccctcgcag ggtttccgca tgacggcagc
     1681 ccagacggag gcattatcct gctggggctc cagcatatcc ttcacctgtt ccataatgat
     1741 ccccaccagc tccctgctgg aacaatccct ggccttttga agagccagga aagaaggttc
     1801 tctcaacagc tcactccaaa cctgcaagcc atccgagcag gccagcaccg catctcccgg
     1861 atgcaagagc aggggcatgg cgctgatgtc caccagttcc atgggaccgc ccataacggc
     1921 ggaacggaga atgcaacgct gccggagcgc accctgaagt gacattttcc ccttccggta
     1981 aaggctatcc gcaatcggcc tcatggaatg gtcttcattc agccggtcca tccgaaagct
     2041 gtccgccccg ctccataaat acagggggga gtctcccacg ctgatccacc acaggaaatg
     2101 gtcgcggatg aagacggcca gcaatgtggt tccggattcc tccggttcct tctgaatggc
     2161 ggacaatgcc ctgttggcag catgcaaagc cgccgttaaa cgttccggga tatcctcgat
     2221 gccgctttcc gcaaataccg cggcaaattc ctgcgccacc acacaggagg cgcaatctcc
     2281 gcgaagatgc cctcccatgc cgtcgcacac gatgcccagc atcccgccgg cggcgggaag
     2341 acttttaacc acgtcttcct gctcgcggcg tttgccaatc cattgggcgg aagcgcagtc
     2401 cagaatatcc ggggtgcggg gaaccatgca gccggtggtt cggattaact gtccttacgt
     2461 ttcaactgcg ggaagagcag cacgtcacgg atggaagagg cccccgtcag catcatgacg
     2521 acgcggtcga tgccgatacc gatgccgcct gcggagggca ttccgtattc cagcgtttca
     2581 atgaaatcat agtccacgcg ctgggtctcc ccggcagcct ggtgctccag gcgttccttt
     2641 tgcacgtcgg gatcgttcaa ttccgaatag ccgggggaaa tttcctgccc gttgatcacc
     2701 agttcatata cgtccactac gtccggattt tcccggttca gcttggccag gggaaccagg
     2761 tccttggcca cgtgggtaac aaagcagggg ttcatggtct tttcctccac cagtttttca
     2821 tacacctgct gggaaacatc cacatctttc atatccgggc tgatttccac tcccagctct
     2881 tcacagcggg cgcggcgcgc ttcgggggag atgtcaaacc agtcttcccc cgccacgccc
     2941 cggatcaggt cctggtagtc ggcgcgtctc cagggccggc tgaggtcgat tgtgtaaaga
     3001 acgttgcctt ccgcgtcctt gtggtcaatc tgaaggccac cgcagaattt ttccgccaga
     3061 tggcagatga gctcctccac catattcgcc atggtttcaa aatcaccgca ggcgcaatag
     3121 gcttccagca tggtgaattc cgggttgtgg cggcggtcaa ttccttcatt gcggaagctg
     3181 cggttgagtt cgaaaatttt cgtgaagccg cccaccatca ggcgtttgag gaaaagctcc
     3241 ggggcaatgc gcagcgtcaa cggcatatcc agcgcgttat ggtacgtttc aaacggcttg
     3301 gcggcggccc caccggccac atcctgaagc atgggggttt ccacttccag ataaccgcgt
     3361 tcctggagaa agcggcggat ttccgcaatc atgagggagc gcgtaacgaa cagggaggcg
     3421 ctttcctcat tggaaatgag gtccaggtgg cgcttgcggt aggtcacctc cttgtccgcc
     3481 agcccgtgcc acttgtccgg cagggggcgg aggcttttgg aaagaatggt cagtccggat
     3541 acctttacgg taggttctcc ggtacgggtc aggaacgtgg ttcccctgat gccgacccag
     3601 tccccgcggt ccaggagctt ccaaagcttc caggtggttt catccacctc atttttatgc
     3661 aggaacccct ggatttttcc ccgtacgtcc ccaatgacga aaaactggga tttgcccatg
     3721 tcgcgaatag ccagaaggcg gccggcgacg gctacctgtt tgtcttcctg gaaatcggct
     3781 ttcaatccgg cgggagtggt ggtcacgtca aatcttgcgc cgtaggggtc aattcccagc
     3841 tcacggattt tggcgagctt gtcgcggcgc acggcaataa gttcggattc cgtcgtagtc
     3901 ggatgtgcct gctgttgttc ggacatagtg cggggattct aaaggcttgc ttccgttttg
     3961 gctagcgcat tgtcaggcag aggggacatt tttggcggcc ggttttgacc cgaaggttcc
     4021 tccccccttt ttcggaagcc ggatgccgga acatgcccca gtactccggc cgttttgcaa
     4081 aaagcctgga cagaaccaca taaagcacga tattcaaagg aattgaaaca aaactggtct
     4141 tattattaaa aaatggccgg caaatcccca catacgcata attgctttta cctttggcac
     4201 cagacatgtt ataaatgttc ccgttaagac gcaccttatt tatcaattat atactatccg
     4261 tgcagactta tgagtgatca gacaaccgta acttacagca cgattgacgc taacgaagcc
     4321 gtagcctccg tagcctatcg tttttctgaa gtcattgcca tttaccccat tacaccatct
     4381 tctccgatgg gtgaatcagc tgaaagctgg gccgctgtca acaggaagaa cctgtggggc
     4441 accgttccct ccgtagtgga aatgcagagt gaaggcggcg cggcaggcac cgttcacggc
     4501 gccctccaga ccggagcgct tgcaactacg ttcaccgcat cccaggggct cctgctgatg
     4561 atcccgaaca tgttcaaaat cgcaggggaa ctgactcccg ccgtgttcca cgtagccgcc
     4621 cggtccctgg cttaccaggc cctttccatt tttggcgacc acagcgacgt gatgagcgcc
     4681 cgctcctgcg gatgggccat gctgtgcggc tcctccactc aggaagctgc ggacttcgcc
     4741 gctatttccc acgctgctac actggaatcc cgcattcctt tcatcaattt ctttgacggg
     4801 ttccgcacgt cccacgaaat cggcaagatt gcagacatca cggacgatac cctgaacggc
     4861 atgattaagc aggaatggct ggattccttc cgggaacgag ccctgacccc tgatgctccc
     4921 gttctgcgcg gcactgccca gaacccggac gtttacttcc agggacgtga aacggtcaac
     4981 cgtttctatg aagccactcc ggctattgtc cagaacgcca tggacaaatt cgcggaactt
     5041 accggccgtt cctaccatct ggtggattac accggcgctc cggacgccga acgcgtcatt
     5101 atcctgatgg gatccggcgc tgaagctgtg gaagaaacgg tagaagccat gatgacccgg
     5161 gaaaacgcca aggtaggcgt gctgaaggtg cgcctgttcc gcccattccc cgccgccgaa
     5221 ctcgtcaagg ccctccccgc tacggtcagg aagatcgctg tgctggaccg caccaaggaa
     5281 cccggctccc agggagaacc gctccaccag gacatcatcc aggccctctt cgacgcccag
     5341 gccaacggca cgctgccctt taccaacggc atgcccaagg tggtaggcgg acgctacggc
     5401 ctctcctcca aggaattcac ccccgccatg gtcaagggcg tctatgacaa cctggctctg
     5461 gacactccca agaatcattt caccatcggc atcaacgacg acgtactggg caccagcctc
     5521 ccgtatgatg aagattattc cacggaagcg gacgacgtga cgcgggccat gttcttcggc
     5581 ctcggttccg acggcaccgt aggcgccaat aaggacgcca tcaagatcat cggccagcat
     5641 acgaacctgt atgtgcaggg ctacttcgtg tatgactcca agaaatcggg ttcctccacc
     5701 atttcccacc tgcgcttcgg tccccgtccg atcaaatcca catacctgat caccaaggca
     5761 aacttcctgg ccctgcacca gccttccctg ctggatctgt tcgacttcct gaagaatgcc
     5821 gccaacggcg ccactttcct gatgaacagc ccgcacccgg cggacaaact ctgggacacg
     5881 ctgcccgccc gcatgcagca gcagattctg gacaagaaca tcaagctcta cacgattgac
     5941 gcttttgccg tggcccgcaa aacgggcatg ggcggccgca tcaatatgat tatgcagacc
     6001 tgcttcttca agctggccag cgtgattccc gcggatgaag ccatcggcta catcaagaag
     6061 gccattgcca aaacctacgc caagaagggc caggaagtgg tggacaaaaa catcgccgcc
     6121 gtggacgcca cgctggaaaa cctgcaccag gtggacacaa ccggaaaaac tgtaaacgga
     6181 cacgccattc cgcccgccat gtccccggac gctccggact acgtacaaaa cgtccttggc
     6241 aagatgatgt gcggtgaagg cgacagcatc ccggtcagcc aaatgcccgt ggacggcaca
     6301 ttcccgaatg gaacgtccca gtacgaaaag cgcaatctgg ccctggatct gccggaatgg
     6361 gatccgaccc tctgcatcca gtgcggcaag tgtaccgccg tctgcccgca cgcggttatc
     6421 cgcagtaaat tcttctctcc tgatgctctt gcaaacgctc cggaagggtt tgaatgcctg
     6481 gatgccaagc atccggactg gaagggagag aaattcgtca tccagatttc cccgaacgac
     6541 tgtacgggct gtacgctctg cgcggatgtc tgcccggcca agagcaagac ggacccgacg
     6601 cacaaggccc tgaccatggt cccggccggg aagattcacg acaaggaaga agccaattgg
     6661 aatttcttcc tgagccttcc ggacgtggac cgcaccaagg taagaacgga caacatccgc
     6721 tccatgcagg tgctgcgccc gctgttcgaa ttctccggcg cctgtgccgg ctgcggtgaa
     6781 accccgtatg taaaaatgct ctcccagctc ttcggcaacc gcctggtggt cgccaatgct
     6841 acgggttgct cctccattta cggcggcaac ctgcccacca ccccgtggtc ccatgactct
     6901 gaagggcgcg gccccgcctg ggccaactcc ctgtttgaag acaacgccga attcggcctt
     6961 ggcttccgcg tctccctgga caagcagatg gaacacgcca ttgagcttct tcatgaagct
     7021 gccggcgccg tgggccagga actggtggac cggatattgg ctaatccgca gaaggatgaa
     7081 gcagacatcg cccagcagcg tgaaaacatt gaagaactca agaagaaaat cgccggcaag
     7141 ccggaatacg cgcgcctcct gacccttgcg gataaacttg tccgcaagag cgtgtggatt
     7201 ctgggcggcg acggctgggc ctacgacatc ggctacggcg gcctggacca cattctggcc
     7261 agcggccgga acgtgaaggt gctggtcatg gatacggaag tatactccaa caccggcggc
     7321 cagtgctcca aatccacccc gcgcgccgca gtagccaaat tcgccacgac cggcaagccc
     7381 ggagtgaaaa aggatctggg gctcatggcc atgacttacg gcaacgtgta cgtagcctcc
     7441 gtcgctctcg gcgccaagga cgaacacacg ctgaaagcct ttgtggaagc ggaagcctat
     7501 gacggtccgg ctctcatcat cgcctactcc cactgcatct cccacggcat caacatggcc
     7561 aagggcctgc agcagcagaa ggcatgggtg gattccggcc gagtcctgct ttaccgctat
     7621 aatccggacc tggcccgcca gggcaagaat ccgctgattg tggaaggcaa gggcccgaag
     7681 ggcgatctgc gcgatgtact gctcagcgaa aaccgcttca aacttctggc gaagaccaat
     7741 aaggaaggat tcgaaaaact ccttgaagaa gcccagaagg atgtctggca ccgctggaac
     7801 ctgtaccaaa gcattgccgg catgggtgcc gacaaacctg cggaataagg tataggccgc
     7861 ttaatttcaa cgcccctgtc cagcttatcc ggcaggggcg ttttttactg ccggatattc
     7921 atgaaaaaca aaccatgaat atttcgggga ggggattgct tttccgcccc gccatacagc
     7981 cacgcaagca ggcttcccgc gccagtactt tcccttcctg aaagccggag aattcatcct
     8041 tcccccgcag cacaaaaaag ggcgcacacc ttgctgcaag gccgggtttt aatatatcac
     8101 cttatacggg ttaatttccg catggagatt ttgaaggcct tcaatgaacc gcagcgtttg
     8161 cggccagcca tgtccaaggc aaagaggagc attttatgcg gccaggggaa tactgtttcc
     8221 tcacaccttc ctccccagag gagcgcggcc cgctttcctg cggaccgcgc cggtggaaaa
     8281 accggaaaaa ggctttaaaa cagggatgct gcttcaagat tcccgaaaat ggtgcacacc
     8341 ggaagaggaa tataccattc cggatgccgt atccgggaag tgcaccacat caggcgtcag
     8401 gcgagtgccc acatccagat agaccagttt ctccgtagcg gatccgttgc gaataacatg
     8461 cgctccctct gggctggcgg ggaatgcaat cgcatccccc tcttctaaat tcttttcacc
     8521 ctcaggcgta cgcacaacgg catggcccct gatgatgtaa aatacctctt cattcacttc
     8581 atgataatgg tagccatagg cgtaccgccc cggctccact tccacgaaac tggccgcaca
     8641 ttttccggca tccgcttccc gaatgacggg ctttaccgca aaggaattac cctcccggct
     8701 gataacctga ggctccgtct ccctgtaatt ggcaatgatg atcttgttca tggcattatc
     8761 tgttcatgct tgccgtaacg gcaggcactt attaaaatag gcggcaacat tctttttgta
     8821 aagtaggcag aaaatagtac cctagattcc tgaaagaaac cattgcttaa aataaatgac
     8881 ttactataat tcatcatgcc ctgttgaaac tactctccaa ctgatttcct cccgctggaa
     8941 agtgctcatc ctccgcgatc tgctcgaagg cacccggcgg tttggagaac tccgcaaatc
     9001 cattgggcct gtgacgcaga aagttctgac cgcgaacctg cgttctatgg aaaaggacgg
     9061 cctgcttacg cgaaaggtgt atgcggaagt acctccgcgc gtggaatata ctcttacgga
     9121 actggggcgc agtctgcgcc ccgtcctggc ctccatggcg gaatggggat cgaaatacca
     9181 aagagaaaac cgctgatcct cccccctttc cggagcttaa ccgaacctcc ggaaagacat
     9241 ggaaatacag cggtttccct ttttcccgca agaaaggtca gcgggaaatt tccgtcgttt
     9301 tacggataat ttcgcgggct ttccgcacgt cttcctcatg ggaatccccg cggctttttt
     9361 ccacggtaaa gagcttggaa agctcttcat ccatgcgggc tacggcagct ttcgccttag
     9421 gattttttgc ggcgcgggcg cgcaggatat tgaccttttc aaattcctcc agtccgtccc
     9481 ggagtttttc aaaccgcagg gaactgagat tgccgggata aacaaggtag cagtctcccg
     9541 cgggccagtt cccgaaatcc gtcttttcaa acggattgcg gttccaggaa ttataagccc
     9601 atctcaaaaa gccgtccaaa tgattggcgg cggcaaagag gggaagccat tccgcctccg
     9661 ccagcggaga aatagtgaag gtgttgggct ttttgggatg gacacagaca tagaacgtcg
     9721 tcttttttcc ctcctttttg cgctgcgcca gcagatcgcc cgtgaccgtg cctgcatggt
     9781 caattacagg agagacgtca taaacgtccc gggtcatggc cgtaggccga ttgacggcgg
     9841 aaacgatttt gaattccggg gcatacttgt ccagtacatt cttggccgcc ctgaccatag
     9901 cgtccggccg ttcatccagc ccgatgcagg ttttgcccag ccagcccttg ctcttgacgt
     9961 gcttgcgaaa atccgtcagg aaaggccccc agatagcttc ataggaggga tcgttcggct
    10021 taagatccag aaatttgtac tttccggtcg cctcatccag ataacggatt ttcatgttcc
    10081 agggaatcat ggtatagcag gatatctgtc ccttgacgcc cacctcgttc atcatgaagg
    10141 aaacccactt gtcaaaattg gcgtaattcc agcgcatggt tccgtttttg cccttgaccc
    10201 attcaatcat gggcgggaac cagtcataag tctgggcatt ccaggcttca tcaatcaggg
    10261 agcatgtaat ggccttttgc ccggcatccg ccagcctttt catcaccggc ttcatcagtg
    10321 cgaaatgctc cggagaccac ggttccacat catgccagcg ggccacggcc tgcggatgct
    10381 gccacaagtc cagatgaact tgccaatgcg cgggagcagg gagggattcc ggcgccacct
    10441 ccagaattac cggcacactg acgggagagc cgctttctgc ggaaactact acttttcctt
    10501 tgtacacgcc gggtttggca gacgggggga tattgacctc cacccatacc ggacgcacgc
    10561 ctccggcttg caaatcgcag ctgttttcgc tgccgatgat atctgaaatc agcctgttgc
    10621 cccccctggt gtagcgtatc atggcagtcc ggacagggat aatctgtccg gcagcgtttt
    10681 ttaccccggc gcaggaggcc gataactggg gctgcgcctg ggaagaccag acggcaatct
    10741 gcccgccagc gcgttcgcct ctccagccgg acagacgcac ggcatcctga agcatttcct
    10801 gcccgggagc gccattgtaa ggaatacggt cataatcctt caccgctgca gcctgcaggc
    10861 tcagagcggc atcgggtccg taccctttga tttccaccag atgccccccc ttctcattgc
    10921 cggcgctatt gcccaaaaaa gtgattttaa cgtaacggac cgtctgcgga ttgaatttga
    10981 agggaacgcc ttccggagtg gcggcaatgc tgttggaaga ctgatccgcc aacattttcc
    11041 agttctttcc gtcttcggaa ccttctattt tatatttgta aatgcgccct ccctcccaat
    11101 agggccatac atgcagggag gaaagcgtcc ggggctttcc catatctatc tggagccaga
    11161 cgggaatgcc ctcgcaaccc cagtatttgc cggcgttatt cgtctgcccg tccacggcca
    11221 gttccggacg gtcactgccg taatgaccgg aagcggttac tttggctccg gcaaataaat
    11281 tacctgcatc acccggagtt cctacggaaa caagggcggg ttcatacagg ggatgcctct
    11341 ccagggactg ggcctggaca aaagacgtta aggcaatagc ggaacacaga ggaaaaaaaa
    11401 gacagcgcat acgcatatta cgcaccggaa tttcattttc tctcaaaaga aaagctgttt
    11461 ccgctattcc gccaaaggac gcacgggtat tcctctggaa gcaaagtaag ccttggcttc
    11521 cggcaccgtg tattccccaa aatggaaaat ggaagccgcc agcacggcat ccgccttccc
    11581 ttccaccagc acatccacca tgtgatccaa attacccgca cccccgctgg cgattaccgg
    11641 aatgcgcacc gcactgctta cggcgcgggt caattcaata tcataacccg ttttggctcc
    11701 gtccgcatcc atgctggtca acaagatttc cccggctccg cggcgttccg cctccacagc
    11761 ccattccacg gcatccagcc ccacgaattt ccggcctcca tgggtggaaa cgccccactt
    11821 gccggaagcc tggcgcttgg cgtcaatagc gacgacgatg cactggctgc caaaagccgc
    11881 cgcaccttca ttaatcagct ccggcctgtt gatggccgcc gtattcaggg aaaccttgtc
    11941 cgcacccgcc agaagcattt cgcgcatgtc ctttacggaa cggatgccgc cgcctaccgt
    12001 cagcggcatg aagcagcatg ccgccgtgcg gcgcaccacg tccgccatgg tggcacggcc
    12061 atcggaagaa gcggtaatat ccagaaaaac aagttcatcc gcctgctggg catcatacgc
    12121 cctggcacat tctacaggat ccccggcatc tctcagatta atgaaattgg tccccttgac
    12181 gaccctgccg tccgttacgt ccagacacgg aatgattctt ttagccagca cggccctatc
    12241 aagccatcac cgccgccaaa ggaaaagcct aaaatacggc ttgccgcggg atgcctttta
    12301 ataaacatgt tccctttttg accaaggccc tcttcggcag cgtttccatc ccgcatatcc
    12361 acggtaagag aaatttactg aaattcatca atatcactat tccactcact ttccggccga
    12421 ccctgcaccg ccatgaagaa acgcagtgcg gcatctgccc ctttcccgcc cgcatgcata
    12481 aaacggccta agagcttttc tttccatgtc caggtggtag agtccgcata aggcatttcc
    12541 attcatgacc actacacgct cgggattcac caaacttgca gccgtctgca ttgccattct
    12601 tctgggggcg gtggtctggg agctgggctg gcccctgacg cgggcggaac atgagtggtc
    12661 gcggctgatt gcagccgttg ccacgctggg ccacctgacg ggcattctgg gttcctattt
    12721 ccggaaggaa atcaaccgcc cttccctgag gctcctgatt ttccaaatca tcagctgcct
    12781 catgattttt ctcctgattg ccagggaaca acaggaagcg ggatacatga ggttcacgga
    12841 actttcccgc ctggtgatta cggccgggct gattgccatc cccacgctga tgtccctgac
    12901 caggattttt gaatggctgg tgggcaagca aaaaaaaggc cggcctctta tggcccccgc
    12961 catgcagttt gtagcttctc tgggagtagt catcctggca ggcaccggat tgcttctgct
    13021 gcctaattcc acatatccgg gtattacact cagttttacg gatgccctgt tcaccagcac
    13081 cagcgcagta tgcgtcaccg gtctgaacgc cgtggatttt gcccatactt tcaccccgct
    13141 gggagaaatg ttcacgcttg cccttatcca gattggcgga ttcggcatca tgacgttcgc
    13201 ctacttcgta gccatggtgg caggccaggg tttttccctg agggaccgcg tgctgctgac
    13261 ggatctgctt gatgaagaca atctgggggc cgtcgtctcc tttatcacca ctattgtggt
    13321 cagtacgctg ttcatcgaac tgtgcggcgc cgtccttctt tatttctcct gggaagggaa
    13381 ggacatcaac ctgatggggg agcctttgtg gtggcattcc ctgttccact ccgtttccgc
    13441 cttttgcaat gctggttttt caactttccc gatgaatttg atggagccgg gcatccgcct
    13501 gtgctacagc gggcaggcgg tcatcatggc actgatcgta tgcggcggcc tgggattcgg
    13561 catttacaag gaaatcaatt cgcgcctggc aaaccgcttt ttttccaaac accgccgcct
    13621 gcacatgcag tggacccctt acttcaaact ggtgatgatc tccacgggga ttttgctggc
    13681 gggaggcgcc ctggccatct ttgccgtttc ctctccccat gccgcggaac cgttggggga
    13741 acacctctgg atttgccttt tcgacagcgt cacggcacgc acggcgggat tcaatatcag
    13801 cgactacggc cgctatctgc ccgcagccag cctcatcatg tgcggtctga tgatggtagg
    13861 aggcagcccc ggcggcacgg caggcggcat gagaaccact acctgcgcca ttgcaggcgc
    13921 ggaaatcctg cgcatcctcc gcggcaggga tcatgtggaa ttcttccgcc gccgcatcga
    13981 ccagcgcacc gtggcgcgct gcgtgattac cgtggtggtc tcctgcgcct ggatcggctg
    14041 ctttaccgtc ctgatttgcg ccctggagcc ctccatgagt tctctggata tcttctttga
    14101 aaactgcagc gcttttgcta cggtaggcgt gtcgcggggc attactccag atttaagcgg
    14161 cccttccaaa taccttctta tcgtcaacat gctcgccggc cgcgtggggc tcttcgcttt
    14221 tctcattgcg ctggccggca cccctactcc gaggcattac cgctatccat ccgtcaaaat
    14281 cccgttaacc tgaatatacc attatgagat acaccgttat cggcctgggc cagtttgggc
    14341 aggaactctg cacagaactt tccgcccgta atattgaagt agtagccgtt gcctccacgg
    14401 atgaagaatt ggagcaaatc aaggatctgg tgacttatgc cgtggtgacg gattacacta
    14461 atccggccgc tttgcgtgag ttggaactgg acgaccagtc cgccgtcatt gtcgccatcg
    14521 gagacagttt tgaagaaaac cttctcgtcg tcacgcacct tcagaaaatg ggcgtccgct
    14581 acatctacgc ccgcgtcatg agtccggtgc acgaacacat tttaagccag atgaacgtgt
    14641 atgcgctcat caacttgtcc cgcgtggctt ccaagcaact cgccagccag ttggaatccc
    14701 cggaattcct gcgcgtctcc cccatggacg aaaaccacag catcgtggaa atagccgtgc
    14761 cgcgcatctg ggtgggcaag cgcctgcggg atgtgggcct gcgcacggaa caccacctca
    14821 acctgctcac catccgccgc ggggaggccc agactccgca ggggcgccgg gaaatcctgt
    14881 ccataccgcg cattcccgtc attggcaccc cttccccgga tctcgttttt gaagaccacg
    14941 acattctggt cctgttcggc aaggaaacca atttgattga attcgcccaa ttatccaaag
    15001 gattgtaaac catcctccgc gagcaggctg agggtatccc tctccatttc agaaaaaggc
    15061 gccggataag ccgcctgtgc aaacagcctc cgtcctggtt ttactggctt gacaatgcct
    15121 caaaagaagc caccagacgt ttttcggaga cgcggccctt gacggagatg gcgggagcga
    15181 aaacggccag gcggtattct tccagcaaat aaccgtattg catccagcgc aggtctccgg
    15241 catgttcctt caaaacctga tgccagggaa aatacacgcg ttcaaagagg tccaggcgtt
    15301 ccaattccct ggcaaggggt tgctggccga tgcgtctgat acgctccgca attccctgca
    15361 tgtaccgttt caggtccggc aagcgttccg ctccatgcgc ccacaggaaa cgggggcgta
    15421 acaaccagtc aagctggcgc tgaaggtcag ccgtgatgcg ctccgtatgg cgcacgccct
    15481 tttgcagcgc cgtaaagtcc ctgacggcat gttccgtacc cgccaccagt tcccatatat
    15541 ccgccacgtt atgcgccgcg tcaaaaaggt tttggcgcag attcatttcc gcagcagcga
    15601 attgctccgc cgtgcgcggc aaaggacggc ccatggctat ctccgcggca acgtccacca
    15661 ggtcttccgc attggtagac ggctcccgtc cgagcatatg aagagagagc tttccttcca
    15721 gcttcaacgg aaattttctg cggagatggt taagctggtc cgtctggcgc aggcgcatga
    15781 aacgcaggca tccttcccgg tgggattccg cagcgctcag ttcatcctca aagacacgga
    15841 cgcccacgga tgctccttca tccaccagag ccacataacc cggccttccc gccacatcca
    15901 ccgtgtattc caaatctccg cagctccatt ccttcatgcc ggttacggac acgatatcct
    15961 ccgctgtttc ctggaaccgg cgggaaagtt ttttacctag gcggttattc agttccgcaa
    16021 catccgtgcc catggcaagc tcttcccctt catcatcaca cacccatatt ttcgtaacca
    16081 gctccgcagg aagacggttc atgtcaaaaa aggagggcgc gcaaaatttt cccgtttcca
    16141 cttccacaaa ttccgccagt tttcccgcca gcggcccgtc cggttccagg ccatgcctca
    16201 gttccgcaaa gtaagcggcc ttttggctga taggctggag aaagacgcgc aaatccttgg
    16261 ga
//
