LOCUS       c00006_gnlPro..        17188 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FGEGDCHJ_6.
ACCESSION   c00006_gnlPro..
VERSION     c00006_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 12:58:18
            Original ID  :: gnl|Prokka|FGEGDCHJ_6
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17188
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17188
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4212:7188]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4213..7188
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17188
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17188
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..613)
                     /locus_tag="ctg6_1"
                     /transl_table=11
                     /translation="MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGEH
                     LPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTLEYKALGYKTISKEVTLKKGKTLEI
                     NVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQPGVR
                     VETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYG"
     CDS             complement(660..1010)
                     /locus_tag="ctg6_2"
                     /transl_table=11
                     /translation="MDRLRKYLRILLPALFIAYLGCIIAFTHVHIVNGVTIVHSHPYHK
                     TDDGRPDHEHGYAEFQLLHQLSVLQITGAAFVAILLAAFYSFIRNLSFAPVYPDYIVPF
                     RGRRTLRAPPIF"
     CDS             complement(1096..2649)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_3"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.7e-46, bitscore:
                     148.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLESTLKEQLKGIFAGLNANYTFDISISPAHESRQELLDLLGDVA
                     SCSDKISMQVSDGEGLEFILLKDGAKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNFPD
                     ESICNRVKALNGPIHLTTYVSLTCTNCPDVVQALNAMTTLNPQIHHEMVDGAINQAEVD
                     ALKIQGVPSVFADGKLIHVGRGEFGELLSKLEAQYGINESLTEKTVKRYDVVVVGGGPA
                     GASAAIYSTRKGLSVAVVAERIGGQVKETVGIENLISVPETTGTQLADNLRLHMRQYPI
                     DLLEHRRIEKVTIEGNEKVLSTAGGEIFKAPAVIVATGASWRKLNVLGEAEYIGRGVAF
                     CPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEKAKSL
                     PNVEIFVSSQTTEVVGNGDKVTGIRTKDRKTGEERVIHLDGIFVQIGLAANSGVFKEIV
                     ETNRPGEIVIDAHCRTNVPGIYAAGDVSTVPFKQIIISMGEGAKAALSAFEDRVRGVLD
                     "
     CDS             complement(2669..3235)
                     /locus_tag="ctg6_4"
                     /transl_table=11
                     /translation="MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFT
                     FVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHD
                     GEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             complement(3436..4014)
                     /locus_tag="ctg6_5"
                     /transl_table=11
                     /translation="MKTPQEIAEMISKRFYPLPDADLDSLASIIESSKAAKGKLLLDNG
                     QISKYLYYVESGLLRQFYYKNKRDITEHFSCEGNIVICIASTFQREPTRLLIEALEPTV
                     YHRISFSEFSDLLKTSLAINRLYQKILEWALMLSQEKADSWRFESARKRYLRFQQEYPE
                     AAKRASVNHIASYLLMTPESLSRVRAGVL"
     CDS             complement(4213..4947)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 68.1;
                     E-value: 3.3e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_6"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-33, bitscore:
                     105.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWNPK
                     GKVKYQMTPGELLTEVLQYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTALD
                     TSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWI
                     RHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLPYHTMGTYKYEQLGLDYPLKGVEPL
                     SKERLDNAKAIFSRYKPENNKA"
     CDS             complement(4948..7188)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_7"
                     /sec_met_domain="Gly_radical (E-value: 4.3e-46, bitscore:
                     145.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.4e-282, bitscore:
                     926.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENECWDHFKGETWKREINVRDFIQSNYTPYEGDDSFLVASSE
                     KTRKVWNKLTEMFKVEREKGVYDAETKLPQGIDVYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTEEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTAILIEEKKRFLNRLDIQEITEEIIQSREEISEQIKAL
                     KAFEKMCASYGFDVTRPAQNAREAVQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEK
                     DIREGKLTEEEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTRTSYRYLHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRG
                     EYLEYDEVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFM
                     EYLRQHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGA
                     IAALASVAKLPFQHAHDGISYTFAVSPATLGKEREVQINNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             complement(7359..9662)
                     /locus_tag="ctg6_8"
                     /transl_table=11
                     /translation="MEQCEENSQENDDVIIEKEISKLIEEQRLFTESIYACLPVGIEIY
                     DAHGVLRSINDHALRMYGVDDRTSVVNIVNLYKSPFVDSELLARIQSGEDISLEFEYDF
                     DRVNKDAYYSSHNKDTMIYGVKVIPIWSRKKHLIGHILLANDMTSVKEVEFRTEESKKN
                     LEMAMKAANMASWVYDVNKKVFNPLYGLTVAKKNMPMEAVLDILHPQDRAPLIRLFSQL
                     IGNEIEQGQMTLRFYNEQEEMYRYYESRMRLSTEHRGKLQIIGTQMDITERLQMAKKAQ
                     DLIAKRDLAMKVSNIVHWDFDVNSQKFESYNDPINDYVSDRLLTVSEYMDVIYPEDRSV
                     FYDAMQSLIAGKNVTINFTCRIQTKYDETWQYCDFMGVPFDQDENGDIIRYTGFRQNIP
                     KIQQLNRELKERNYKIELSFKTVGMSYWDFDVKNLKFSAFNDPINDFYSEKTITPEDYL
                     NATHPDDVVFVRKYMEHMFRGIDKDFNVKYRSKTKWDDEWQTLLVTGIQVERDKEGHVT
                     RYTGITINNTKWEKMIQQLKELKEKAELSDRLKSAFLANMSHEIRTPLNAIVGFSELMV
                     TCDDPEEKKEYINIIQSNNELLLRLINDILDLSKIESGIIERRKENFNLAKVCNELFVT
                     IQAKMTNPNVELRLDGPNSECWVLLDRNRLKQVWMNFLTNAVKCTKSGYIKMGYGIERK
                     GLRIYVEDTGIGIPDDLHDKVFTRFEKLNEFSQGTGLGLTISRAIVEAAGGEVGFTSKL
                     GVGSTFWAWLPLRP"
     CDS             9819..13859
                     /locus_tag="ctg6_9"
                     /transl_table=11
                     /translation="MRFTRLILALTSFLILITQTDLFASTVLHKTSMVDLSNNAIICMH
                     QDPDGYLWIGTYDGLNLYNGKDTYVYRFELNNKNSLCSNIIHKISDAEPGFLWISTSLG
                     INKFSLKERKVTESFPGYMECDLLASDSSGITLAICKENRISCYTPSSDGFRDLPREGV
                     GPQTVRTLFAGTDGHFYLLLASGILKKLTPDFSDTTFNLLSEERQFHNKPILSAFYENN
                     HIFIVDTDNKLYRQHVDGKGKEFLFDLPEITKQYGNIIKICTFQSNVYIVFRNGNILDL
                     SQPENTINMGIGIFCLMNDKRQEILWLGTDGQGIRMFYDKPDLFGSILLKDLPINIQNP
                     IRSLYTDDDQSLWLGTKGDGIVRIQAYDTYHNKKMIPQSAITHFTTADGLSSNRVYCFQ
                     KSEYHPCIWIGTEGPGLTYYSYKEKRIKTIPQREDTTPLRYVHSICEVDDSTLWLATTG
                     NGLQKVTLHIDKAVPTIGKVQTFPLKNGKNICKEIQSMVYDNDSTLFLGSRGGYGVIRF
                     NIFNQGYEFLQTNNLRNPAIGDVLSVCQTEDSTFYAGASSGLTRIKFRGGKMRLRQFDK
                     SDGIVNDMIHGIHEGNDSCIWLSTNKGLTKYNPRNNFFHNYHQPYFSVTEFSDDAYWKC
                     PYSERLFFGGINGLVWVNKQTEPEHTYQPELSFFELQMDKQILPLYKDISRNGVTVPAD
                     VQSLTIAFVAPDYINGENYEYSYQLVNYNSSWEKLQKTNKVTFMNLPYGEYLLKVRYRN
                     DVIDSSAKEYTLPIKVLPPIYLSSLAIFTYLFIGTVLLIIATYRIHHQILKKQKQIADK
                     IKEEQKEKLYESKLNFFTHITHELCTPLTLINGVENYIQAYAATSKDKTLEKYTSVLRE
                     NVEELNGLIQEILDFRKAEDAGFSHTHIRRVSVSSLLRTQFEWFYPLSEQHQIQFKIDA
                     PKELYWNTDSVYFKKILANLISNAFKYTEDGGTVRISLHEEENFLVLKVYNTGKGIEEA
                     DMQNIFDRYRILGTMDNDDNRQNTTRNGLGLFICHSLVQSLGGKIDIESEVGQYAEFTV
                     TLPFGIIEETSDNTIDEEIPVSLPSPNTDIQKPQISHTAQKETEDKPMILVIDDHKDIV
                     WLITETLSSEYQVQEAYNAEEALEFLKQYTPSLIITDIMMPNIDGLELISLIKENRYTR
                     HIPLIIVSAKISDQEQAAGLNIGADAYLTKPFSPTVLLSVVNRLMTNQRELKEYFYSPE
                     SAYQYTEGQLLHQEDKEFLDAVTAIIKENVSKEGLGPELVADALNINTRILYRRFKKIS
                     TMTPSDFIKDYRLNYAAQLLVNTNMSVQEIIYNVGISNKSYFYREFARKYNMTPKEYRT
                     KEA"
     CDS             14062..17124
                     /locus_tag="ctg6_10"
                     /transl_table=11
                     /translation="MEKKSEGKTRKCLTLLGGRTSLLLCLSLMFQSSYAAGDSTVPEMG
                     NMEIHQIAQQSSTIKGVVKDQKGEPLIGVSIVVKGTTNGTASDFDGNFTLDVPDNSTLV
                     FSFIGFKLQEVRYTGQKTLNIVLAEDSETLDEVVVVGYGSQKKGEITSSVTSVKASDFN
                     KAPVVNPMQLVEGRVAGLTVSRGSTDPNGEVKVQMRGASSLKGSNEPLVIIDGMPGNMT
                     SLNAIAPEDIEAIDVLKDGSAAAIYGTRGNNGVIIVSTRHPQAGTTQVDYSGYIMHEAV
                     YKRPEILNGDEFVAYGKETNNANIRDFGGRDNHYDALLNKSNFTHVHNLTATGGNGKTN
                     YRASLNYKKNDGMIRNTSRETINGSIAVNHRAFDDKLQLSFNLANSFVKVDAVSDDVDK
                     VGDIPNYGILYQAIRINPTMPIYKEDGSFWETYSGYEDFNPVARIYQRTKKKEFKNLLA
                     NFKAQYEIIPGLTAAAFFAMEKNDALTNDYSMREEYSQYKDGTNGRAKKEYYQNTNRTT
                     EWTANYNTSINGVHNITGLLGYSYQDFEYEQFSAENKNFLTDVFGTNNLEAGGYLKDGK
                     AEMKSKKETSKLIAFFARANYNYDGKYMASASIRREGSTKFGANNKWAWFPSVSAGWMI
                     SREDFMESQEVFDVLKFRAGFGITGSLPTDPYMSLATYGTGAGAWNAYTGSWLTATYGP
                     NINPNPDLKWEKNESLNVGFDFGLLGGRLNGTIDWYSRTTRDLISSYNAQQPSLIYNTI
                     TTNVGTMRNRGIELALNAEVVKTKDFSYTANFTFSYENNKLTSLSNDVYKSSYEDQYDL
                     PSPGNPGKAYRLQEGQPIASFFGYVCDGINPDGTWNLRDIDGKEGLSDADRTFIGNGLP
                     KFKAGLQNTFTYKNFDFSFFLRGMFDYDVLNEGAIYFGTTVNIDQSGTNVYKDALKNKV
                     TEQPLFSSYYLEKGNFLKIDNVTLGYTFNFKNNKYVRNLRIYGNVTNLATITGYSGLTP
                     DVNVTGLQAGIEKRGSYPTTRTFTFGVNFGF"
ORIGIN
        1 gcccatatac gccggataaa gcgctgaata tgggacgtga atcaatcagt atttgggtat
       61 aaggtccgtc taatccattg atccggactt gctggaaacc gcaattctgg caattcgtct
      121 ctacccgtac acccggttgg aaatttagtc cctgtgccaa attcaccgca ttggtcgtag
      181 taaaaacctt cgcatccaat acattcacta atgtgggagc caaccggcgg gaagtttccg
      241 cacgattcgc agataccacc acgccatcca aggcgatctg gtcttcttcc agttctacat
      301 taatctctaa ggtttttcct ttctttaggg tcacttcttt agagatagtc ttatacccga
      361 gcgctttata ttctagcgta aatttacctt ccggcagatt cttcaggaaa taatgtcccg
      421 agttatcggt ggtcgtaccg atcgtggtac cttttaacaa tacgttgata aagggaagat
      481 gttcccctgt tttcttatcc aatacatgtc cgaaaacatt tgcgtctgag tcgtttagac
      541 ggtcctctcc cgtggcctga gctaccgtta gggcacagca caggcatagt ataaagatga
      601 aaaatttatt cattttaatt tattctgata agtaatacaa tgttattaat ctcacaatat
      661 cagaatatgg gaggagcccg aagcgtacgt cttccccgga agggaacgat atagtccgga
      721 tagaccggag cgaaagataa gttacggata aaggaataaa aagccgccag cagaatagcg
      781 acgaaagccg cacctgttat ctgcaagaca gataactgat gaagcaactg aaactcggcg
      841 tagccatgtt catggtccgg acgaccatcg tccgttttat gatacgggtg agaatggacg
      901 attgttaccc cgttgacaat atgaacgtgg gtaaacgcaa taatacatcc caaataggct
      961 atgaacagcg cagggagtaa tatcctcaga tattttctta atctatccat ctcttttctc
     1021 tcgatcgcaa atatagtaat ataaccgata aaagagatac gctgttcaaa aattacctat
     1081 ttgtaggtac tttcctcaat caagtacgcc acgtacccga tcttcaaagg ccgaaagggc
     1141 cgctttggcg ccttctccca tagaaataat gatttgctta aagggtacgg tggaaacgtc
     1201 gcccgctgca taaatacccg ggacattcgt ccggcaatgt gcgtcaatca cgatctcacc
     1261 gggacgattt gtttcgacaa tctccttaaa gacaccacta ttagcggcta agccgatttg
     1321 aacaaaaata ccgtctaaat gaataacacg ctcttcccct gtcttacgat cctttgtacg
     1381 gataccggtt accttgtcgc catttccaac cacctcggtt gtttgtgaac taacaaagat
     1441 ctcgacattc ggcaaactct tcgctttctc ttgcaagact tgatccgctt ttaactcatc
     1501 cataaactcc aaaacggtta ctttcgaaca gatccccgcc aaatcaatag ccgcctcgat
     1561 accggaattt ccaccgccaa ccacggcaac atgttttccc ttataaaacg gaccgtcgca
     1621 atgaggacaa aaagccactc cacgccctat atactctgcc tcacccagta cattcaattt
     1681 acgccagcta gcgcccgtag cgacaataac cgccggagcc ttgaatatct cacctccagc
     1741 cgtagataaa accttctcgt ttccttctat cgttaccttc tctatacgac gatgctccag
     1801 caggtcaatc ggatattgcc gcatatgcaa gcgcagattg tcagccaact gggtacctgt
     1861 tgtctccgga actgaaatca gattctcaat tcctaccgtc tccttcacct gcccgccgat
     1921 acgctccgcc acgacagcga cactcagccc ctttcgtgtg gaataaatag cggcagaagc
     1981 accagccgga cccccaccga ccacaaccac gtcatatcgt tttaccgtct tctccgtcag
     2041 gctctcattg attccatact gagcttccag cttcgataac aattcaccga attccccacg
     2101 tcctacatgg atcagttttc catccgcaaa gacagagggg acgccttgta tcttcaaggc
     2161 atcaacttcc gcctgattga tagccccatc taccatctca tgatggatct gaggatttaa
     2221 agtcgtcata gcgtttaatg cctgtaccac atccgggcaa ttcgtacaag tcaaagagac
     2281 ataggtcgtc agatgtatcg ggccattcaa ggctttaaca cgattacaaa tgctctcgtc
     2341 cggaaaattc ttgcctttcc catctgaatt caagatcgcc aacagcaagg aagtaaactc
     2401 gtgtccatta ggtactccac gaaacttaat ccccgttttc gctccatcct ttaataaaat
     2461 gaattccaat ccctccccat cagatacctg catagatatt ttatccgaac aagaggcaac
     2521 atcacctaat aaatccaaca attcctgtct actttcatgc gcaggagaga tcgatatatc
     2581 aaaggtataa ttcgcattta accctgcgaa tatacctttt aattgttctt ttaatgttga
     2641 ttctaacacg atctatactc ttaattattt agattttccc taccaagtca atgctaggtt
     2701 tcaaggtagc ctcccctttc ttccatttag caggacaaac ctcaccatca tgtgaagcga
     2761 caaactgagc ggcttcaact ttacgaagta actcggaagc gtcacgaccg atattgttat
     2821 catgaatctc ggccactttg atctttcctt ccggatttac caagaaagtg ccacggtatg
     2881 ccataccctc ttcctcaatc atcacaccaa acgcacgact cagtgctcca gtgggatccg
     2941 ccaacatcgg atattggatc ttacggatag tctcggaagc gtcatgccaa gctttatgta
     3001 caaaatgaga gtctgtactt acagagtaaa tttctactcc cattgattta aactgctcat
     3061 acttctcagc catatcgacc aactctgttg gacaaacaaa tgtaaaatcg gccgggtaga
     3121 agaaaaagat agcccactta cccaagacgt cctcgttggt tacagtcttg aaattaccat
     3181 tttgaaaagc ttgtacttta aactccggaa gttgagaatt aataatcggt tccatacttg
     3241 ttcctatttt taaatgaata ctatttgttt ttatttccga tacaaaaata taacatattt
     3301 cttcattaaa acaatttttc taatcgatat attttatgag gttatagata atactttatc
     3361 aatcaataaa aagggcctat cctcacggat aagcccttca atatcttggg ttttggatta
     3421 ccgcatcagt aacgattata acactcccgc ccgcacccgg ctcaaagatt cgggtgtcat
     3481 caataaatac gaggcgatat gattgacaga agcacgtttc gctgcttccg gatattcctg
     3541 ttgaaaacgc agataacgtt ttcttgccga ctcaaaacgc caagagtccg ctttctcttg
     3601 cgaaagcatc aaagcccact ccagtatttt ctggtacaat ctattaatag ctaaagatgt
     3661 tttcaataaa tcgctaaatt ccgaaaaaga gatccggtga taaaccgtcg gttccaatgc
     3721 ctcgattaat aaacgcgtcg gttctctttg gaatgtgctg gctatacaaa taacgatatt
     3781 tccctcacag gagaaatgct cggtaatatc acgtttattc ttatagtaaa actggcgtaa
     3841 taatcccgat tccacataat ataaatattt agatatttgt ccgttatcca acaataattt
     3901 tcctttcgca gccttacttg attctatgat cgaggccaga gaatccaaat ccgcatcggg
     3961 taatggataa aaacgtttgg atatcatttc ggctatttct tgtggtgtct tcatactatt
     4021 catcattttc tgatctatat cattttttat ctccttacaa aaatagatat ttgttgcata
     4081 taacaaaaca aacacatatt aaatagtcaa ggttagtcta ggcaaaaaat tattactatc
     4141 gtttaaaagc taatcggatt agattgtttt ccctgattag ctgttgcata atcgcaaggc
     4201 ttgatcgaga gatcaggcct tgttattttc tggtttgtag cgagagaata tcgctttcgc
     4261 attatctaaa cgttcttttg ataagggttc cacccccttt aacggataat cgaggcctaa
     4321 ttgctcatat ttataggttc ccatcgtatg ataaggcaat aattccactt tgcgaaccac
     4381 tttatatgaa ctgacatacc gagctaacgc ctccagccac tcgtcattat ccgtatatcc
     4441 ggggacaata acatggcgaa tccaagtatc tatgccacgt ctctccaatt catccaagaa
     4501 cagaagcgta ttatcctgct tgacacccgc cagtaacgga tgtaaatccg ggtttaaggt
     4561 tttgatgtcc aataacacta agtccgcata atccaagact tcccaagctt ttgaggtaca
     4621 tacgaaacca gatgtgtcca aagctgtgtg aagaccttgc tcttggcaca aacggaaaaa
     4681 ctctttcaga aactcaggtt gcaataaagg ttccccaccg gtaacagtca cccccccacg
     4741 ggcgataaaa ctcttatact gtaagacttc cgtcaatagc tcgccgggag tcatctgata
     4801 tttcaccttc cctttcgggt tccaagtatc cgggttatgg caatacaggc aacgcaacgg
     4861 gcagccctgc ataaaaacga caaagcgaat tccgggacca tctacggtcc cgaaactctc
     4921 taatgaatgt atcttacctt ttatcactta cagtgaatgg ttaatggttc ttgaaataac
     4981 atccaactgt tgttcacgag tcagtttcac gaagtttacc gcatatccgg atacacggat
     5041 cgtaagttgc ggatatttct caggatgttc catagcgtcg atcaacaaat ccttatcaaa
     5101 tacgttaaca ttcagatgct gacctccatc cggagtaaaa tagccatcca ataagctaac
     5161 cagattattg atctgcactt cacgctcctt tcccaacgta gccggagaaa cagcgaaagt
     5221 ataagagata ccgtcgtgcg catgctggaa tggaagcttc gctaccgaag ctagcgcagc
     5281 gatagcacct ttcgtatcac gaccgttcat agggttcgcg cccggagcga aaggagttcc
     5341 accgatacgg ccatccggtg tcgtaccagt cttcttacca tataccacat tagaggtgat
     5401 cgtaaggatg gactgcgtag gtttcgcatg gcgataggtc tcgtgctgac gcaaatattc
     5461 catgaacttc tcggtgatct ctacagcgat actatccgta cgatcatcgt tattaccgaa
     5521 aggaacatat tcgccctcac gttcgaaatc aaccgccaag ccacgctcgt cacggatcac
     5581 acgtactttc gtatcacgga tagcagccaa cgaatcggca acgatagaaa gaccggcgat
     5641 acctgtcgca cggatacgct ctacatcccc atcgtgaagc gacatctcga atgcctcata
     5701 cgcgtattta tcatgcatat aatggattat cttcaaggcg ttcacataca ctttcgccaa
     5761 ccagcgcatc atttgctcat acttagccat cacctcatcg tattccagat actcgccgcg
     5821 aaccggctcg aacatcgggg ctacctgtac gccgctgcgc tcatcccgtc ctccgttgat
     5881 cgcatataat aaacatttcg ccaaattcgc acgggctccg aagaactgca tctgcttacc
     5941 gatcttcata ggagaaacgc aacaagcgat accataatca tctccataat ccggacgcat
     6001 caaatcgtcg ttctcatatt ggatagccga cgtatcgata gagaccttgg cacagaaacg
     6061 tttccagttc tcgggagcgt tcttaaacca cagaaccgtc aaattgggtt ctggtgccgg
     6121 acctagatta tataatgtat ggagataacg ataggaagtt cttgttacca aagaacggcc
     6181 atccactcct tggccgccca aggactctgt tacccaaacc ggatcaccgg agaacaaatc
     6241 attgtattcc ggcgtacgta agaaacgaac gatacgcaac ttgatgatca gctggtctac
     6301 caattcttgc gcctcctctt cggtcaactt accctcacgg atgtctttct cgatataaat
     6361 atccaaaaac gtagaagtac gtccgataga catcgccgcg ccatcttggt cttttaccgc
     6421 cgccagataa gctaagtaca caaactgaac tgcctcacga gcgttttgtg ccggacgagt
     6481 cacatcaaag ccatagctag cgcacatttt ctcgaacgct ttcaaagcct tgatctgttc
     6541 ggaaatctcc tcacggctct ggatgatctc ttccgtgatc tcttggatat ccaaacgatt
     6601 caagaaacgc tttttctcct cgatcaagat tgccgtacca tacagagcga cacgacgata
     6661 gtcaccaata atacgtcctc taccatatgc gtcgggcaga ccggtgataa tagccgaacg
     6721 acgtgcggca atcatctctt ccgtatatgc ggagaaaacg ccctcgttat gcgtcttacg
     6781 gtacttcgtg aagatctctt tcgtcatcgg gtccaaatga taaccataag cttccaagct
     6841 attctcaacc atacggatac cgcccttcgg gaagatacca cgtttcagcg gagcatcggt
     6901 ttgtaaccca acgatcacct cattctcctt atcaatatag cccgggccat atacatcgat
     6961 cccttgaggt aattttgtct cggcgtcata aactcccttt tccctctcga ccttaaacat
     7021 ctcggtcagc ttgttccaga ccttacgggt cttctcggaa gaagcgacta aaaaggaatc
     7081 atccccttca taaggcgtat agttactctg gataaaatct cttacattga tctctctttt
     7141 ccaggtctca cccttaaagt gatcccagca ctcattctca aatttcataa acaatcttat
     7201 ctaataccac atttttaccg ccgcaaaggt aggagaatta tcgtcatatt tctgtcacat
     7261 atgctacacc agttctaaaa tccctataaa ttgcgataaa aaagcttctc atccttcact
     7321 attttaaaag gacattacca ataaatgggg agtcagacct aagggcgaag aggcaaccat
     7381 gcccaaaaag tagatccgac accaagtttt gaagtaaagc ccacttctcc ccctgccgct
     7441 tctacgatag ctctggagat cgtcaagcca agtccggtac cctgcgagaa ctcattcaat
     7501 ttctcaaaac gggtaaatac tttgtcatgc aaatcatccg gtataccgat tcccgtatcc
     7561 tcaacataga tacgaagacc tttcctttca atgccatatc ccattttaat atatccggat
     7621 ttggtgcatt ttaccgcatt agtgaggaaa ttcatccata cttgcttaag ccggtttcta
     7681 tccagaagta cccagcactc cgagttggga ccatctaaac gtaactcgac attcggattt
     7741 gtcatcttcg cctgaatcgt aacaaataac tcattacaaa ccttagccag attgaaattc
     7801 tccttcctac gttcaattat gcctgactct atcttggaaa gatcaaggat atcgttgatc
     7861 aatcgcaata acaactcatt attggattgg atgatattta tatattcttt tttttcttcc
     7921 ggatcatcac aagttaccat taactctgaa aaaccaacaa tagcgtttaa cggggtacgt
     7981 atctcgtgac tcatattagc gagaaacgca gacttgagac gatccgaaag ttccgctttc
     8041 tcctttaatt ccttcaattg ctgaatcatc ttctcccact tcgtattatt gatcgtaata
     8101 ccggtatagc gagtcacatg gccttcttta tctctttcaa cctggattcc agtaaccaat
     8161 aaggtctgcc actcgtcatc ccatttggtt ttggaacgat atttaacgtt gaaatcttta
     8221 tctatgcccc ggaacatatg ctccatatat ttccgcacaa aaaccacatc atccggatgt
     8281 gtagcgttca aataatcctc gggagtgatt gtcttttccg aataaaaatc attgatagga
     8341 tcattaaaag cactgaattt caggtttttt acatcaaaat cccaatacga cataccaacc
     8401 gtcttgaaag aaagctctat cttgtaattt ctttctttaa gttcccgatt caattgctgg
     8461 atcttaggaa tgttttgcct gaatcccgta tagcgtatta tatctccatt ttcatcttga
     8521 tcgaaaggga cacccataaa atcacaatac tgccaagtct catcatactt ggtttgtatg
     8581 cgacaggtaa aattgatggt gacattcttt ccagctatca gggattgcat tgcgtcgtaa
     8641 aaaacagacc ggtcctcggg gtatataaca tccatatact ccgaaacggt caataaccga
     8701 tctgaaacgt aatcgttgat cggatcatta taagattcga atttctggga atttacatca
     8761 aaatcccaat gaacaatatt actgactttc atggccagat cacgttttgc gatcagatcc
     8821 tgcgctttct tggccatttg caacctttcg gttatatcca tttgtgtccc gatgatctgc
     8881 aattttccac gatgttctgt cgataggcgc atccggctct cataataacg atacatctct
     8941 tcttgctcgt tatagaaacg caaagtcatt tgtccttgtt ctatctcatt tcctatcaat
     9001 tgagagaaga gccggattaa cggagctcga tcttggggat gcaaaatatc cagtaccgcc
     9061 tccattggca tatttttttt ggctacggtt agtccatata atggattaaa aaccttttta
     9121 ttcacatcat atacccaaga agccatatta gccgctttca tggccatctc cagatttttc
     9181 ttgctttctt ccgtacggaa ttccacctct ttcacggaag tcatatcatt tgcgagtaat
     9241 atatgtccga taagatgttt ttttctactc catatcggga taactttaac cccatagatc
     9301 atcgtgtctt tattatggga agaataatat gcatccttat taacccgatc aaaatcatac
     9361 tcaaactcca aggaaatatc ttcacccgat tgtatccgag ctaaaagttc tgaatcaaca
     9421 aatggacttt tgtaaagatt gactatattc accaccgatg tccggtcgtc cacaccatac
     9481 atcctcaacg catggtcgtt tatactacgc agcacaccat gtgcgtcata aatttcaata
     9541 cccaccggca gacaagcata tatactctcc gtaaataaac gctgttcttc tattaattta
     9601 gaaatttctt tctctattat cacatcgtca ttttcttgag aattctcttc acattgttcc
     9661 atctgtcact tactttattt cgtattatca tacgtcagac attctaattt atacgaaagc
     9721 cctgcttttt gcaaaagtaa acaaaaaagt gaattctttt ctgttcgttc ataaagatat
     9781 tatctttgcg ctgaaaacaa acactaaatc ttaaatacat gagattcaca aggcttattc
     9841 tagcgttaac cagtttcctt atattgatca cgcaaacaga cctatttgcc tcaaccgtat
     9901 tgcataaaac ttctatggtt gatctctcga acaacgccat tatctgcatg catcaagatc
     9961 cggatggcta tttgtggatc gggacttacg acggacttaa cttatacaac ggaaaagata
    10021 cgtatgtata tcgtttcgaa ttaaataaca aaaactctct ttgtagtaat atcattcaca
    10081 aaatatccga cgcagaaccc ggctttttat ggatatcaac ctctttaggt atcaataaat
    10141 tctcactaaa agaacggaaa gtcaccgagt ctttccccgg atacatggaa tgcgatctat
    10201 tagcgtccga ttcatccggc atcacgctcg ctatttgtaa ggaaaacagg atctcttgct
    10261 acaccccatc tagcgatggg ttccgggacc tgccgagaga aggagtaggc cctcaaaccg
    10321 tacgtacctt attcgccggg acggacggac atttttattt attattagcc tcgggcatac
    10381 tgaaaaagtt gactccggat ttctccgata ctacttttaa tttgctatcg gaagaacgcc
    10441 aattccataa taaaccgatc ttatccgcat tttacgagaa taatcatatt ttcatagtag
    10501 ataccgacaa taaattatat cgacagcatg tagacggaaa ggggaaagaa ttcctgttcg
    10561 atctgcctga aataacaaaa caatatggta acatcatcaa gatatgcacc ttccaatcca
    10621 atgtgtatat cgttttccgt aacggcaata ttctagacct aagccaaccg gaaaacacga
    10681 taaatatggg catcggtatc ttttgcctga tgaacgataa aagacaggag attctctggt
    10741 taggaacaga cgggcaaggt atacggatgt tttatgacaa acccgatctt ttcggctcta
    10801 tcttactcaa ggatttaccg attaatatac agaaccccat acgttcttta tatacagatg
    10861 acgatcaatc cctttggctc gggacaaaag gagacggtat tgtccggata caagcgtatg
    10921 acacttacca taacaaaaag atgatcccac aaagcgctat cacgcatttc accaccgccg
    10981 acggcctatc cagcaaccgg gtgtattgct tccaaaaaag cgagtaccat ccatgtatct
    11041 ggattggcac ggaaggcccg ggactgacct attattcgta taaagagaaa cgaataaaaa
    11101 cgataccgca acgagaagac accacccctc tacgctatgt ccactctatt tgcgaggtag
    11161 atgattccac attatggcta gcgacaacgg gtaacggatt gcaaaaggtt accttacata
    11221 tagataaagc cgtacctaca atcgggaagg tacaaacctt cccgttaaaa aacggaaaga
    11281 acatctgtaa agaaatccaa tcgatggtat atgacaacga ctctaccctg ttcctcggaa
    11341 gccgtggcgg ttacggagtc attcgtttca atattttcaa tcaaggatat gaattcctgc
    11401 aaaccaacaa tttaagaaac ccggccattg gagatgtgct ttccgtatgc cagaccgaag
    11461 attccacgtt ttatgcaggc gccagctccg gtctcacccg gattaaattc agagggggaa
    11521 agatgcgttt acgccaattc gataaaagcg acgggatcgt aaacgacatg atccatggta
    11581 tccatgaggg gaacgatagc tgtatctggc ttagtaccaa taaaggtctc accaaatata
    11641 atccccggaa caactttttc cataattatc atcagcctta ctttagcgtc acggaattct
    11701 ctgatgacgc ttattggaaa tgcccatact ccgagcgttt attctttgga ggcatcaacg
    11761 gattagtctg ggtaaataaa caaacggagc cggagcatac ctatcaaccc gaattaagtt
    11821 tcttcgagtt gcaaatggat aaacaaatcc ttccattata taaggacatc agccggaacg
    11881 gtgtaacggt tccggctgat gtgcaatcgt taacgattgc gttcgtcgct ccggattaca
    11941 tcaacgggga gaattacgag tattcgtatc agttggtcaa ctataattcc tcttgggaaa
    12001 aattgcaaaa gacaaacaag gtaactttca tgaacctacc gtacggggaa tatttgctga
    12061 aagtccgtta tcgcaacgat gtcattgatt cgtcagcaaa agaatacact ctacctatca
    12121 aggtattacc tcctatttat ctaagctcgt tagccatttt cacgtatctt tttatcggta
    12181 cggttttgct catcatcgcc acctatcgta tccatcacca aatactaaag aaacagaagc
    12241 agatcgcaga caagatcaag gaggagcaaa aagagaagct atacgagtcc aagctgaatt
    12301 tctttaccca cattacgcat gagctatgca ccccgcttac cttgatcaat ggcgtggaga
    12361 attatatcca agcctatgcc gccacctcaa aagacaagac attagaaaaa tacacttcag
    12421 tcctccggga aaatgtagag gaactgaacg gacttatcca agaaatcctt gatttccgga
    12481 aagcagaaga cgcaggattc agtcatacgc acatccggag agtatccgta tcctctcttt
    12541 tgcgaactca attcgaatgg ttttacccac tatccgagca acaccaaatc caattcaaga
    12601 tcgatgctcc caaagagctt tattggaata cggattccgt ctatttcaag aagatcctag
    12661 caaatctgat ttccaacgca tttaagtata cggaagacgg gggcacggtt cgtatctcct
    12721 tacatgagga ggagaacttc ctcgtcctta aagtttacaa caccggcaaa ggaatcgagg
    12781 aggcagacat gcaaaatatt ttcgaccgat atcgtatcct tggcacgatg gataacgatg
    12841 ataacaggca aaatacgaca cggaatggcc tcggcttatt tatctgccac agcctcgtac
    12901 aatccttagg tggtaaaatc gacatagaga gtgaggtcgg ccaatatgct gaatttacag
    12961 ttaccttacc ttttggcatc atagaggaga cctcagacaa cacgatagac gaagagattc
    13021 ccgtatcgct tccttcccca aacacggata tacaaaagcc gcaaatctca catacggcac
    13081 aaaaagagac ggaagataaa ccgatgatac tcgttatcga cgatcataaa gacatcgtct
    13141 ggctaatcac ggaaaccctc tcttccgaat atcaggttca ggaagcttat aatgcggagg
    13201 aggctctgga attcctcaag caatacactc cctcccttat catcaccgat atcatgatgc
    13261 ctaatatcga cggattggaa ttgatctctc ttatcaagga aaatagatat acccgtcata
    13321 tcccgcttat tatcgtatct gccaaaatat cagaccaaga gcaagcggca ggacttaata
    13381 tcggagcgga tgcctatcta accaagcctt tctcgccaac agttctccta tccgtcgtga
    13441 atcgattgat gactaaccaa agagaattaa aagagtattt ctattctccg gaaagtgctt
    13501 atcaatatac ggaagggcaa ttattacatc aagaagacaa ggaattcctt gacgccgtaa
    13561 ccgctatcat caaagaaaat gtcagcaagg aaggactcgg tcccgagctg gtagcggacg
    13621 cattgaatat aaacactcgc atcttatatc gtcgtttcaa gaaaatatct actatgacgc
    13681 cgagtgattt tataaaggat tataggttaa actatgcagc gcaattactc gtgaatacca
    13741 acatgagcgt tcaggaaatt atttataatg taggaatttc taacaaatca tacttctata
    13801 gggaatttgc ccgtaaatat aacatgacac ctaaggaata ccgcacaaaa gaggcataaa
    13861 tcattgattc ctaaacagtg tcataatcta ccaaaaaagt atcataatct gctatatgca
    13921 tttcatgaca cttctttggc atttcaaagc actcttcaat tcgttaagac ctattaatat
    13981 tgctgtcgaa tagcaaagca aaccgcttgt gtgtattctt ccttcgggaa gcacattatt
    14041 aacttttaat ttaatgtttt tatggaaaaa aagagtgaag gtaagacgag gaaatgcctg
    14101 actttattag gtggacgaac ctctttgtta ctttgtttat ctttaatgtt tcagtcctct
    14161 tatgcggccg gagattctac tgttcctgaa atgggaaaca tggagattca tcagatcgca
    14221 cagcaaagtt caaccattaa aggtgtagta aaagaccaaa agggtgaacc tctgattggc
    14281 gttagtattg ttgtgaaagg aaccacgaac ggaacagctt cggactttga cggaaatttc
    14341 accttggatg tgccggataa cagcacattg gtattttcct tcatcggctt caaactccaa
    14401 gaagttcgtt ataccgggca aaaaacattg aacatagtct tagctgaaga ctctgagaca
    14461 ctagacgagg tagtagtcgt tggctacggt tcccaaaaga aaggtgagat cacctcatcc
    14521 gttaccagcg tgaaagcatc cgactttaac aaggcaccgg tagtgaaccc gatgcaattg
    14581 gtggaaggac gtgtagctgg tctgactgta tcacgtggta gcaccgaccc taatggcgag
    14641 gtaaaagtac agatgcgtgg tgcctcatct ctgaaaggta gcaatgagcc tctcgttatt
    14701 attgacggta tgccgggtaa tatgacttct ttgaatgcta tcgcacccga ggatatcgag
    14761 gcgatcgacg tattgaaaga cggttccgca gccgctatct acggaacccg gggtaataac
    14821 ggtgtgatca tcgtctccac gagacatccg caagccggaa ctactcaagt ggattactca
    14881 ggatatatca tgcacgaggc ggtttataaa cgaccggaaa tcttaaatgg agacgagttc
    14941 gtcgcttatg gcaaggaaac caacaacgcc aatatccgcg actttggtgg acgggataac
    15001 cattacgacg ctttattgaa taagagtaat ttcacccatg tacacaactt gaccgctaca
    15061 ggtggtaatg gtaagacaaa ctatcgcgct tctttaaatt acaaaaagaa tgatggtatg
    15121 atccgtaaca ccagccgtga aacgatcaat ggctctatcg ccgtgaacca ccgtgcgttt
    15181 gatgataaac tacagctttc tttcaatcta gcaaactctt tcgtgaaagt ggacgcagtt
    15241 tccgatgatg tggataaggt aggagatatc cctaattacg gcatattata ccaggcgatc
    15301 cgtatcaacc cgacgatgcc tatttataag gaagacggct ccttctggga aacttacagc
    15361 ggttacgaag atttcaaccc ggtagcccgc atataccagc gtaccaagaa aaaggaattc
    15421 aagaatttat tggcgaactt caaggctcaa tatgagatta tccccggtct gacagccgcc
    15481 gctttcttcg ctatggagaa gaacgacgca ttaactaacg attatagtat gcgtgaggaa
    15541 tatagccaat ataaagacgg tacaaacgga cgcgccaaaa aagaatatta tcagaatacc
    15601 aaccgtacta ctgaatggac agcaaactac aatacttcca tcaacggcgt acacaatatt
    15661 accggtttgc tgggatacag ttaccaagat tttgaatacg agcaattcag cgccgagaac
    15721 aagaacttct tgacggacgt attcggtacc aataacctag aagccggcgg ttacctaaaa
    15781 gatggtaagg ccgagatgaa gagtaaaaaa gagaccagca aactgatcgc cttcttcgcc
    15841 cgcgccaact ataattatga cggtaaatac atggccagcg cctctatccg ccgtgaaggt
    15901 tccacgaagt tcggagcgaa caacaaatgg gcttggttcc cctctgtcag cgcaggctgg
    15961 atgatctctc gtgaggactt catggagagc caagaagtat tcgacgtatt gaaattccgt
    16021 gccggtttcg gtatcacggg tagtctacct accgatccgt atatgtctct cgctacctac
    16081 ggtacaggcg ctggagcttg gaacgcttac accggttcat ggctaaccgc cacttacggt
    16141 ccgaatatca acccgaatcc agatttgaaa tgggagaaga atgaatcctt gaacgtaggt
    16201 ttcgacttcg gcttgctagg tggacgccta aatggtacga tcgattggta tagtcgtacg
    16261 actcgcgact tgatcagtag ctacaatgcc caacagccat ctttgatcta caacacgatc
    16321 accaccaacg taggcacgat gagaaataga ggtatagaat tagcattaaa cgcagaggtc
    16381 gtaaagacta aggatttctc ttacacggct aatttcacgt tctcatacga gaataataaa
    16441 ttgacatctt tgtctaacga cgtgtacaaa tcttcttacg aggatcaata tgacctgccc
    16501 tctccgggta acccgggcaa ggcttaccgc ctacaagaag gacagccgat cgcgtcattc
    16561 ttcggttatg tatgcgatgg tatcaacccg gacggaactt ggaatcttcg cgacatagac
    16621 ggaaaggaag gtctgtctga cgctgaccgt acctttatcg gtaatggttt gccgaaattc
    16681 aaggctggct tacagaacac atttacctat aagaactttg acttcagctt cttcctgcgc
    16741 ggtatgtttg attatgacgt attgaacgag ggtgctattt atttcggaac gactgtcaat
    16801 atcgatcagt ctggcacaaa cgtatataag gatgccttga agaacaaggt aacagagcaa
    16861 ccattgttct cttcttatta tctagagaaa gggaacttct tgaagatcga taacgtgaca
    16921 ctaggttata cattcaactt caaaaataat aaatatgtgc gcaacttacg tatttatggt
    16981 aatgtcacca atcttgcgac tattacagga tactcaggtt taacccctga cgtaaacgta
    17041 acaggactac aagcaggtat agagaagcgc ggatcttatc ccaccacccg taccttcacg
    17101 tttggcgtta attttggatt ctaattaagt aacaatagat ttaagacaat acaatgaaag
    17161 ctttaaaaaa tatatgcgca atttcatt
//
