LOCUS       c00068_gnlPro..        14123 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KABDNPCD_68.
ACCESSION   c00068_gnlPro..
VERSION     c00068_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 14:21:38
            Original ID  :: gnl|Prokka|KABDNPCD_68
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14123
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14123
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4478:10464]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4479..10464
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14123
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14123
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             212..1420
                     /locus_tag="ctg68_1"
                     /transl_table=11
                     /translation="MEKLDDMKLTVLYIEYRNFFIDVLSRFYGFEKYDIYHYSEILNVD
                     ELCRNEALNWDMYLIEFWGKEKINWEYLSGNKCLSWTADLFDKYYDYWEWDILSSNEGI
                     FWNELLLNKYKSKLNWNLLSLNKSLPWSIDFINRYVDRLNWVNLSANLSLPWSDYLLEY
                     YENLWDWNLISANPSLPWTDDLIIKYMDRLNWAGLSMNPALPWSSEFIQKYKYNWIWGY
                     SSDWVMTDDIGLCGNSGIHWNEELIEMFDGFIDWGELSLNTGDMWNECLIDKYLCKLHW
                     EECWCPPLGMGGLSSNPSLPWSLDFVDKYKPYLNIKEICSNMSFPWREEDFRNNNGGII
                     NDCDKSYWKLLSMNEGLPWSVGVLYDNRCWFDWNLMKGNVKVYDNCLSVLEKEKMKFLL
                     ELV"
     CDS             1942..2538
                     /locus_tag="ctg68_2"
                     /transl_table=11
                     /translation="VVVVCNVLVAGCASGKVFDRVEKIPHRKVGLLLGTAPVTPWGTKN
                     LYFTYRIDAAVKLFHAKKVDYFIVSGDNHSTDYDEPTCMRDSLVACGVPDERIISDYVG
                     FRTLDLEVRCKAIFGQDSVTVISQSFHNERAIYLAGHNQIDAIAFNAQDVTSVWTTWLR
                     GHSRELLARVKIFIDLIIGKQPRFWGEKVKIPEIR"
     CDS             2614..4161
                     /locus_tag="ctg68_3"
                     /transl_table=11
                     /translation="MAALYPIGIQNFEKIRKEGYLYVDKTALIYQMVKTGSYYFLSRPR
                     RFGKSLLVSTLEAYFQGKEELFEGLAMEKLEQDWLEYPILHLDLNAERYSEASSLDSIL
                     QRHLNLWEDTWGKDEREKTLSDRFIGVIRRAKARSGRRVVILVDEYDKPLLQAIGDELL
                     QDEYRSILKPFYGVLKTMDGDIRFALLTGVTKFGKVSVFSDLNNLMDISMDDRYVEICG
                     MTETEIHAYMEQGVLDLTRNLQMDYEEVCMELKRRYDCYHFTHRSQGMYNPFSLLNTFA
                     KSDFGDYWFETGTPSYLVELLKHTDYDLYNMAHTETNADVLNSIDAVSRNPIPVIYQSG
                     YLTIKSYNPRFKIYTLGFPNQEVEEGFLNYLLPYYTSVNVIDTSFQLFKFIKEIESGDV
                     DAFLSRLQSFFADTPYELIRNLEVHYQNVLFIVFKLVGFYVKVEYRTSRGRIDLVLQTD
                     HYIYIMEFKLDGTTEEAMRQIEEKQYALPFASDERKLFKIGVNFDNETRNIAGWSVD"
     CDS             4479..6314
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_4"
                     /sec_met_domain="ILVD_EDD (E-value: 2.9e-218, bitscore:
                     714.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRAAGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             6341..8041
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             8054..8608
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_6"
                     /sec_met_domain="ALS_ss_C (E-value: 1e-18, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             8645..9376
                     /locus_tag="ctg68_7"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             9418..10464
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_8"
                     /sec_met_domain="IlvN (E-value: 1.1e-48, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.5e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             10966..14121
                     /locus_tag="ctg68_9"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKVEKIMGSGFAEALQGMSAGVNVVNVQGNPGADAR
                     VEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAANGV
                     VMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDGMNM
                     QQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEYVWD
                     EDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYSFRT
                     NLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSEKTG
                     ERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNLKFR
                     SALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLSGEW
                     MIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSLLSF
                     FGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWIDNL
                     SLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDLKWE
                     SNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDLRNS
                     GIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSLYEF
                     IAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITNNFQ
                     FKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDADVLIPRWSY
                     NQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVYVTGNNLLTFGPA
                     KKRY"
ORIGIN
        1 cgggcgagaa ctattttggt gcggttgccc tgtattttcg ctttctttct tgcaagttca
       61 agattttctt gataacttgc cactgtgttt cttctaaatc cgtacaatac ataattattt
      121 gaaacttagt aattaaaaat aattatttta gcagaaagag gaaacacttt atttatttca
      181 aactgtgaaa tttaaacagg ctctaattat tatggaaaag ttggatgata tgaaattaac
      241 tgtattatat attgaatata gaaatttttt tattgatgta ttaagtagat tttatggttt
      301 tgaaaaatat gatatatatc attatagtga aattttgaat gttgatgaat tgtgtagaaa
      361 tgaagcttta aattgggata tgtatctgat agaattttgg ggtaaagaaa aaattaattg
      421 ggaatatttg agtggaaata agtgtttgtc atggacagca gatctttttg ataaatatta
      481 tgattattgg gaatgggata tcttgtcttc taatgaggga atattctgga atgagttgct
      541 gcttaataag tataaatcta agttaaattg gaatttgttg agcttaaata aatcgttacc
      601 gtggtcaatt gattttataa atcgctatgt tgatagatta aattgggtta atttaagtgc
      661 taatctgtca ttgccttggt ctgactattt gttggaatat tatgagaatt tatgggattg
      721 gaacttgata agtgccaatc catcgttgcc ttggactgat gatttaatca ttaaatatat
      781 ggatcgttta aattgggctg gattaagtat gaatccagcg ttaccttgga gttctgagtt
      841 tatacaaaag tataaatata actggatctg gggatattca tcagattggg taatgaccga
      901 tgatataggt ttatgtggca attcgggtat tcactggaat gaggaattga tagagatgtt
      961 tgatggtttt attgattggg gagagcttag tttaaataca ggagatatgt ggaatgaatg
     1021 tttgattgat aaatatttat gtaaattgca ttgggaagaa tgctggtgtc ctcctttggg
     1081 tatgggaggt ctcagtagta atccttcatt gccttggagc ttggactttg tggataaata
     1141 taaaccttat ttaaatataa aagaaatttg ttctaatatg tctttccctt ggcgtgaaga
     1201 ggattttaga aataataatg gtggaataat aaatgattgt gataaatctt actggaaatt
     1261 attgagtatg aatgaaggtt taccttggtc tgtaggagta ctatatgata atagatgttg
     1321 gtttgattgg aatctaatga aaggaaatgt gaaagtatac gataactgtt taagtgtttt
     1381 agaaaaagaa aagatgaaat ttttacttga attagtttga ttgaagtatc aaaaaatggt
     1441 cgtggatgat tgggtaggat agttatataa gtgacgaagc tgaagaaaag aatatgcgcc
     1501 tatattttat agaaaagtct attgctatgc taatacaagt aaagatcgtg tgttgaaaaa
     1561 tatgacatcg tattttgggg acagtgaaaa tattattagt taatacagtc tgcaaaattt
     1621 atattactct gataggttgg agcaatcgtt ctttgcaggg atgatatgtt ttatccggta
     1681 atgattggtg aagacggaag ctttcctgtc aaatgaaata tgacatgctt atggctttgg
     1741 atatgtctgg aaataatacc tttgctatat gccttttaca aaaatattcc taagaagaaa
     1801 tagattgttt tattaggatt gttattttgt tggtgacaat cctttataat aaaagagcaa
     1861 gtctgtgaaa aaaagtaatt caaagtaaga agaaaatcat acaattaacc attatttctg
     1921 ctcatttctg tcataaacat agtggttgta gtttgtaacg tgttggtggc aggttgtgcc
     1981 tcaggtaagg tatttgacag ggtggaaaag ataccacatc gtaaagtcgg tttgttgttg
     2041 gggactgctc cggttactcc ttggggaacg aaaaatcttt attttacgta tcgtattgat
     2101 gcggcagtca aattgtttca tgcaaaaaag gttgattact ttattgtaag tggtgataat
     2161 cattcaacag attatgatga gccgacttgt atgcgtgatt cgttagttgc ctgtggtgta
     2221 ccggatgagc gaattatttc ggattatgtc ggttttcgaa cgcttgattt ggaagtgcga
     2281 tgtaaagcca tttttggaca ggatagcgtt actgttattt cgcagtcttt tcataacgag
     2341 cgtgcgatct atttggcggg tcataatcaa atagatgcga ttgcattcaa tgcccaagat
     2401 gtgacttctg tgtggacaac ctggttgagg ggacatagtc gtgagctttt ggctcgggtt
     2461 aaaatattta tagacttgat tattggtaag caaccccgtt tttgggggga gaaggtcaag
     2521 attccggaaa tccgatgaaa atgtaatata ataagatact tattgataaa aaataagtta
     2581 cctttgtctt gatagataat ataaaaacgg tttatggctg cactttatcc tattggcata
     2641 caaaatttcg agaagattcg taaggagggg tatctctatg ttgataaaac agcgttgatt
     2701 tatcaaatgg tgaagaccgg gagttattac ttcctgagtc gtccgcgccg tttcggcaaa
     2761 tcgttgttgg tttcgacttt ggaggcctat tttcagggta aggaggagtt gttcgaggga
     2821 ttggcgatgg agaagctgga acaggattgg ttggagtatc cgatattgca tttggattta
     2881 aatgcggaga ggtattcgga ggcttcgtcc ttggatagta ttttgcaacg tcatttgaac
     2941 ctgtgggaag atacatgggg aaaagatgaa cgggaaaaga ctttgtccga tcgttttata
     3001 ggggtgatcc gccgggcaaa agctcgatcg ggaaggcgtg tggtcatttt ggtggatgaa
     3061 tacgacaaac ctttgttgca ggctattggg gatgagctgt tgcaggatga ataccgttct
     3121 atattaaaac cgttttatgg ggtgttgaag acgatggacg gtgatatccg ttttgctttg
     3181 ctgacaggtg tgacaaagtt cggtaaagta agtgtgttca gtgatttgaa caatttgatg
     3241 gatatttcga tggatgatcg ttatgttgag atttgtggta tgaccgagac ggaaatccat
     3301 gcgtatatgg aacaaggggt gttggatttg actcgtaatc tgcaaatgga ttatgaagaa
     3361 gtttgcatgg aattgaaacg ccgttatgat tgttatcatt ttactcatag gtcgcaaggc
     3421 atgtacaatc cgttcagttt gttaaacaca tttgcgaagt ctgactttgg agattactgg
     3481 tttgagacag gtaccccctc ttacttggtc gagctgttga agcataccga ctatgacttg
     3541 tacaatatgg cacatacgga aacgaatgca gatgtgttga acagtatcga tgccgtttcg
     3601 cgtaacccga taccggttat ttaccaaagt ggttatttga cgatcaaatc ctataatcct
     3661 agatttaaaa tatatacatt gggctttcca aatcaggaag tagaagaggg gtttctgaat
     3721 tatttgcttc catattacac ttctgtcaat gttattgata cttccttcca gctttttaaa
     3781 ttcattaaag aaatcgagtc tggggatgtg gatgctttcc ttagccggtt gcaaagtttt
     3841 tttgccgata cgccatatga attgattcga aatctggaag tgcactacca gaacgtcctg
     3901 ttcatcgtct tcaaactggt cggtttctat gtgaaggtgg aatatcgtac ttcccgtggt
     3961 cgcattgacc tggtgttgca aaccgatcat tacatttata taatggagtt taagttggat
     4021 ggcacgacag aggaggcgat gaggcagatc gaagagaagc agtatgcctt gccttttgcc
     4081 tcggatgaac ggaaactttt taagataggg gtgaactttg ataatgaaac acggaacata
     4141 gccggttggt cggtcgattg atgtagattt taataatact gttaaaatgc aagatgaacc
     4201 gccctctttt attgataaat gaaagaaaaa gtaagatttt tcttttaaat cctttgctcg
     4261 tacaaattat tattctacat ttgcagcgtc aaacaaaata aagacgataa gaaaagatga
     4321 tgaacaatgt attacatatt attctcgtgg tggtccttct agtcattagt aggtaaggag
     4381 aaaggtgtgt aagaagttgt gaagtcgtaa aagatatttc ttaagccttt ctccatatag
     4441 agaagggctt ttttattgac taaaagataa aaacagatat gatgaagaat ccgttaagaa
     4501 gctcctatag cacagaaggc agacgtatgg ccggagcccg tgcattatgg cgtgccaacg
     4561 gcatgaaaga agaacagttc ggtaaaccga tcattgccat tgtgaattca tttacccagt
     4621 ttgtaccggg ccatgtgcat ctacacgaga tcggacagca ggtaaaagcg gaaatcgaaa
     4681 agctcggttg ctttgccgca gaatttaata cgatcgctat tgatgacggt attgctatgg
     4741 gacacgacgg aatgctttat tctctgcctt cccgcgacat cattgctgac agtgtggaat
     4801 atatggtgaa tgcgcataag gctgatgcaa tggtttgtat cagtaactgc gacaagatta
     4861 ctccgggtat gctgatggcc agtatgcgtc tgaatattcc gacaatcttt gtatccggcg
     4921 gtccgatgga agccggtaat ctggacggac gtgcactcga tttgatcgac gccatgattg
     4981 aagcggctga cgattctatc agcgatgaac aagtagaaaa ggtggaacgt tccgcttgcc
     5041 cgacctgcgg ttgctgttct ggtatgttca cggctaactc tatgaactgt ctgaacgaag
     5101 cgattggatt ggctcttccc ggcaacggaa cagttgttgc aacacatgcc aaccgtaccc
     5161 gcctgttcaa aaaagccgcg aagatgattg ttgataatgc ctttaaatat tatcgtgacg
     5221 gcgatgattc cgtattgcct cgcagtattg ccacccgtca ggcctttctg aatgctatgt
     5281 cgctggatat tgccatgggg ggatcgacga atacagtcct tcacctgttg gccgtggctc
     5341 atgaagcgga agtcgatttt acaatgaaag acatcgatat gctttcacgc aaaacaccgg
     5401 ttatctgtaa agtggctccg agttgttctt atcatgtgga agatgtgaac cgtgccggag
     5461 gtattatcgg tattatgaat gagctggtaa aagccggtct ggtggacggt tccgtgaaac
     5521 gtgcggatgg tctgactttg aatgaggcta tcgaccaata ctgcattacc tctgtaaatg
     5581 taacggaaga agcaatcaat atttataaaa gtgctccggc ccaccgtttc aatctggtgc
     5641 tcggatcgca ggaaagttat tataaagaac tggataccga ccgtgcagcc ggatgtatcc
     5701 gcgatgtgga acatgcttat gtgaaagacg gcggtctggc tgttctgtat ggaaatattg
     5761 cacaggacgg ttgtgtggtt aaaacagccg gggtagatga aagtatcttc cgttttgccg
     5821 gccctgccaa agtattcgat tcgcaggatg ccgcttgcga aggtatcctg aaagatcaag
     5881 tcgtctccgg cgatgtcgtc gttatcacct atgaaggtcc taagggtggt ccgggtatgc
     5941 aggaaatgtt gtatcctacc tcttatataa agagtaaaca tctgggtaaa gaatgtgcgt
     6001 taatcacaga cggacgcttc agcggtggaa catcgggttt gtcaatcgga catatttctc
     6061 ccgaagcggc tgcaggcgga gcgattggct tagtgaaaga cggcgatatt atcgaaatta
     6121 atattcccga aagaaccata catgtaaagg tgacagacga agaactggcc aaacgccgtg
     6181 aagcggaaga agcccgcgga acaaaagcct ttacacctcc tttccgccaa cgtacggtat
     6241 cgaaagcact gaaagcatat gcaaagatgg ttgcttcggc cgataagggc ggtgtacgaa
     6301 tagtagaaga ttaataaaca ccaaatacta tattttagag atggacaaac aaaagataac
     6361 cggttcggaa gctttgctga aagcgctgat cgctgaagga gtagatacta tcttcggtta
     6421 tccgggtggg caggcgatac caatttacga tagtttatac gattacagag atcagttaaa
     6481 acatattctg gtgcgccacg aacaaggtgc aacacatgct gcacagggat atgcccgtgt
     6541 ttccggaaaa gtgggagtaa cggtggttac ttcgggtccc ggggcaacca ataccatcac
     6601 tggtattgcc gatgcgctga tggacagtac accgatggtg gtgattgccg gccaggttcc
     6661 gtctccgctg cttggaacag atgctttcca ggaagttgat gtgatcggta tcacacaacc
     6721 gattaccaaa tgggcttacc agatacgccg cccggaagaa attgcttggg ccgtttcccg
     6781 tgctttctat atcgcatcga ccggtcgccc gggacctgtg gtactggatt tggcgaaaga
     6841 tgcacaggtg ggtttggtag attatgagta tcagaaagtg gattatgttc gtagttacca
     6901 acctgaaccg gatatcaggg aggaacgtat cgaggcggct gcttcattga taaataatgc
     6961 caaaaagcca ttctgtctgg tagggcaggg ggttatcctg ggaggagctg aagaagaact
     7021 gaaagaattc ttgttgaaaa acgatatacc agccggttct accgtattgg gcttgtctgc
     7081 attaccttcg gacttcccat taaataaagg tatgttgggg atgcatggaa atgtcggacc
     7141 gaaccgcaag acaaacgaat gtgacgtgct gattgctatc ggtatgcgtt tcgatgatcg
     7201 cgtaaccggc gacctgaaga cttatgccaa gcaggcaaag attatccacc tggatatcga
     7261 caattcggag atcggaaaga atgtgccggt cgacgtgaaa gtgctgggaa atgccaagca
     7321 tacgattccg atgattacgg ctttactgga agaacggaag cgtccggaat ggaatgctga
     7381 attcgaaccg gatgaaaaag aggaatataa taaggtaata gaaaaagaac tctatcctac
     7441 cgaaggccaa ctgaaaatgg gcgaagtagt ccgtaaggtt tccgaagcaa ccgataatga
     7501 tgcgattctg gttacggatg taggtcagaa ccagatgatg ggtgttcgct atttcaaata
     7561 taaacaaaca cgcagcgtag ttacttcagg aggtttggga acgatgggct ttggccttcc
     7621 cgccgccatt ggagcgaagc tgggagcgcc tgaccgtacg gtctgtttct ttaccggcga
     7681 cggtggtatc cagatgacta tccaggagtt gggaactatc atgcaggaaa atctgaatgt
     7741 aaagatcatc gttcttaaca acaatttcct gggaatggta cgccagtggc aggagctgtt
     7801 cttcaacgaa cggtattcga ataccatcat gaagaatccg gattttgtag cgatagccaa
     7861 ggcttttggt attgcttccc gtgcggtaga taaacgggaa gacttggatg aggcgattgc
     7921 tgaaatgttg aatcacgatg gtgcctatat gttggttgcc aatgtggaaa cttgtggtat
     7981 ggtatatccg atggttccgg ccggaggaag cgtgacaaac atgattttgg gtgataagta
     8041 aggaggagaa actatgaata caaaacaatt atataccgtt attatctttt cggaaaacac
     8101 tgttggtctt ctgaatcaga taactgttat ctttacgcgc cggcaactga acattgagac
     8161 gctttctgtt tctccctctg ctataaaggg aatacataag tttacaatta ctacctttgc
     8221 cgacgaggat acgatcgaca aggtcgtaaa acagatcgac aagcgtgtgg atatcctgaa
     8281 agcctattat aatacggatg aagacctggt ttaccaggaa atcgctcttt ataaactgag
     8341 taccgaactc tttatcaaga tggggacggt tgaggatctg atccgtaagt acaatgcccg
     8401 tatccttgaa atgaatgagg attgtgtggt gttggaaaag agtggtcatt atgatgagac
     8461 acaggctttg tttaaagaat tgagtgagac gatcggtgtc ctgcaattta tccgttccgg
     8521 acgcgttgct ataacgaaga gtaaggtaga acgtctgagc gacatgttat ctgcaatgga
     8581 aaagaagttg caggaaaaac atgtctgaga ataataagga aacattttgt aaataaagta
     8641 aattatggag aagaacaaag taggagaatt tcatttcgta acagagtctt atctgacgga
     8701 cttccgggga cgtattacaa tccctatgat cggaacttat ttgttgcatg ctgcttcttg
     8761 ccatgccgcc gaccgtggat tcggatataa cgatatgacc gaaaggcata ccgcctgggt
     8821 tctttcccgt ctggctatcg agatgacttc ttatcctgcc atgtctgaat ccgtaacttt
     8881 atatacctgg gtggatgagg tcggtaagtt gtttaccagc cgttgctttg aactggtgaa
     8941 cggcgaaggc aagacctttg gctttgcccg ctctatctgg gcggctatcg atatggaaac
     9001 ccgccgcccg accttgctcg atgtggaggg cctgagtgct tatatcaccg accgtccctg
     9061 tccgattgaa aaaccgggta aaattgctcc ggtggaaaac aacacttccg gcgaacctta
     9121 ccgtgtgaag tatagtgacc tggacgtaaa cggccacctg aacagtatca aatacatgga
     9181 acacctgctc gacttgttcg atatcagtct gttccgagaa aaagagataa gccgtttcga
     9241 aatagcttat cagtccgaag gaaagtatgg gatggagctg actctccata accaggaagt
     9301 atccctcgat aaatataata tggcaatctg taacgacggc aaagccatca gccgcgctgc
     9361 cgttacctgg atctgaaaaa caaattattt tatatacatt ttaatagtaa aaagaaaatg
     9421 gcagtaatga attttggcgg cgttgacgaa aacgtagtaa cccgcgaaga atttccgttg
     9481 gaaaaggcaa gagaagtatt gaaagacgaa acaatcgctg taataggtta cggcgtacaa
     9541 ggtcctggcc agagcctgaa cctgcgcgac aacggtttta acgtaattgt aggacaacgt
     9601 aaaggtggta agacctggga aaaggccgtt gctgacggtt gggtaccggg cgaaacactg
     9661 ttcgatatcg aagaagcatg cgaaaaagca actatcatcc agtatctgct ttcagatgct
     9721 gctcagattg aagtttggcc gcgcatcaaa aaatacctga ctccgggtaa ggctttgtat
     9781 ttctctcacg gattcggtat cacttacaaa gaacgtacaa acatcatccc tcctgctgat
     9841 gtagacgtaa tcctggttgc tccgaaaggt tcaggtactt cactgcgccg tatgttcttg
     9901 cagggtcgtg gtctgaactc aagctacgca atcttccagg atgcaacagg caaagcatgg
     9961 gatcgcgtga ttgcactggg tatcggtgtt ggttctggtt acttgtttga aacaacattc
    10021 aagaaagaag tttattctga cctgaccggc gaacgtggta ctttgatggg agctatccag
    10081 ggattactgt tggctcagta cgaaactttg cgtgaaaacg gtcacgaacc ttctgaagca
    10141 ttcaatgaaa cagtagaaga actgactcag tcattgatgc cgttgttcgc agaaaacggt
    10201 atggactgga tgtatgcaaa ctgttcaaca actgcacagc gtggtgcttt ggactggatg
    10261 ggcccgttcc acgatgctac aaaaccggtg ttccagaagt tgtatagcga agttgcctgc
    10321 ggtaacgaag cacagcgttc tatcgacaca aacagcaagc ctgactatcg tgaaggtctg
    10381 gaaaaagaac tggctgctct tcgcgaaagt gaaatgtggc gtgcaggtgc tgttgttcgt
    10441 aaacttcgtc ctgaaaacaa ctaataaatg gtgatacatt aatagttaaa cattttgtga
    10501 tataaaaacg gcaatccggc ttttcgggtt gccgtttttt tatggtttat gtaatgcgtt
    10561 aatggttaaa aaatgttttt gattgcaact gttattgatt tttcatccca atatgtatgt
    10621 cattgtttga atgtggattt tagataaaaa aatcaattaa atggtggtta aaatatattt
    10681 attagagcaa taaatataca taattatgct tgtattaaat aatgataagt tatatttgct
    10741 gatggagata ctgtagtttg tagagtggaa atatagaagg atgttgtgtg taatgatcag
    10801 tatatctttg ttttagttaa ctttatttta ttgaaatgta tgccagtcac ttttatctta
    10861 gaaaagtgta acctctaatg aaatgaacgc tattgtgatt aattttattt aattaaagac
    10921 ttgaatttag ctatgtggac caactcaaaa ctaattagat cactaatgat ttctgtatta
    10981 ttaggtgcgg caggtgcgat tgctgccaat cctacaggtc cggaaacgat ggtagtacaa
    11041 cagggtaata aggtaaccgg cctggtagag gaccagatgg gacctgtcgc cggagcttct
    11101 gttgtagtga aaggaaccac tatcggtacg ataaccgata tcgatggaaa gtttacgctg
    11161 gataatgttc ggcggggagc ggttattgtt atttcctttg tcggcctggc cactcaggag
    11221 atcacttgga acggacaatc tattttaaat gtaaaattaa gtgatgcgac acaggacctg
    11281 gatgaagtcg ttgtcgtagc ctatggaacg gctaagaaat caaccttcac cggatcggcc
    11341 tccgttgtaa aagtcgaaaa gatcatgggc tccggctttg cggaagcatt gcaggggatg
    11401 agtgccggtg tgaatgttgt gaatgtacag ggtaaccccg gagctgatgc ccgtgtggag
    11461 atccgtggta ttgcttccat gtccggaaag gccgatccgt tatatattgt ggacgggatg
    11521 ccttacgatg gaaaactgaa tcagatcaat cctacggaca tagaatcgat gacggtgctg
    11581 aaggatgcgg cggccacttc gctctacggt tcgcgtgcag caaacggcgt cgtaatgatt
    11641 acaaccaagc ggggtaaatc agaaaaaccg cgtattaact tccgcggagg ttggggtact
    11701 tcggataatg ctgtcaagaa tccgaaaaaa gccgatccgt accagcagct ggaaaatacc
    11761 tggtatgcct tgtattatga tgcccttctt tatgacggca tgaatatgca acaggcgggc
    11821 gattatgctt cgtcgcaggc attgaccaaa caggtaaagg ctacaaaaga ttcgaatggt
    11881 aatctgattt atgtcactcc gttcagacat atcaatgaaa attacgtatt gcatgacggc
    11941 aatgggaatc cttacatgaa tcctaatctg gaatatgtct gggatgaaga tgattgggat
    12001 gtctacaaag ctatcttctc ccgtaaactg cgccaggatt atagtgtgga tataagtggt
    12061 caggccaatg gtggaaaaac agcctatttc ttctccggcg gttatctgga cgaccaggga
    12121 tatggtaacc ggcagtatta taaacgttat tctttccgta ccaacctgag tacagagttg
    12181 ttcgattggt ggaaagtggc cggtagcctt tcttattcgc gtcatcgcca gaacctttcc
    12241 ggtggtgcca gccgtgcggc taactttacg acgactttgt cttcaccctg gttacgtaat
    12301 gaagataata ccggttgggt cgtttctgaa aaaacagggg aacggatgta cagttacggt
    12361 aaatatacca ataacttctt tggtgcccat atcctgaata actcgggtga ttattgggat
    12421 aatccgaacg atgacagttt cgataacaat atggggcata tcctgtctgc tcaggtaaat
    12481 acagagttta ctcttccttt caacctgaaa ttccgttcgg ctttgaatat tgacgattac
    12541 tggtatcgta ccatgcaata tacttccgcc gtacatggca gcggacagac tgcaccttat
    12601 ggtatttcta tactggcaga cggtggttat gccagccgtt ataatttcaa taaacgttcc
    12661 accacctgga ataatgtatt gtctggtgaa tggatgattg gtgaccatac gatttcaggt
    12721 ctggtcggac atgagtggta tacctgggac tcccactacg aacaaggttg gggtgaaggt
    12781 atcatggaac tgggtaaata tgaattatcg aataccacca agaacttcgg tgtttccggc
    12841 ggacgtgata aatactctct gctttcgttc tttggtaagg tcgattataa cttcttgaat
    12901 aagtattact tgtccgcttc acttcgtgag gatggttctt cccgtttcag ctccgatcat
    12961 cgctggggta cattctggtc gacaggcggt tcatggcgaa tatcgaaaga aggttttatg
    13021 gaagacctga aatggattga taacctttcg ttgcgtggta gttacggtac gactggtaat
    13081 gataagctga tcgtgcgtga atcgaatggt aaggcagggg atgaagtcct ttacggatac
    13141 cagggtactt atgaaagtga tgacctgtat ctgaaatccg gtttaaaacc atctacctat
    13201 ccgacaccgg acttgaagtg ggaaagtaat cagcaatgga atatcggttt agatttttcc
    13261 gtattcaacc gacttagcgg tacagtggaa tattattccc gtacttccca tgacttgttg
    13321 tattataagg aactgcctct ctctgcccag gttggtagtg catccgggta taatatgaat
    13381 atcggtgacc tgcgtaatag cgggattgaa atcacattga atgcgaatat ccttacaacg
    13441 aaagatttca gatgggatat cgatgccaac atgagtacgc tgaaaaatga ggtgacttat
    13501 ttgcctacag gtccttacac ttattctggt accgcctgta cctacaagat ggaggaaggc
    13561 aagtctctgt atgaatttat cgctccccag tacgacggtg ttaatccgga aaccggagta
    13621 cccggctggt tgatccgcga tggtaacggc ggttggaaac gtacggaaaa gcaggaagaa
    13681 gtaacgacag acgattttgt gtactgtggc tccgcgattc ccaaagtgtt cggtgctatc
    13741 accaataact tccagttcaa agggatcgac ctgtcgttca tgttctatta ttcttatggt
    13801 tccaaaatat cggactatac atataaagaa cgtatcatga accgtccggg tgtcggtgtg
    13861 atacaggagt tggttgagga cagatggcgt cagccgggcg atgcggatgt gcttatccca
    13921 cgttggtcgt acaaccagta tggcgcgacg gtaaaatatg cagataactt cgtattcgac
    13981 aaccactact ggcgtctgag aaacctgaca ttaggctata cgctgcctaa gagccttacc
    14041 cgcaaggccc tggtagaaaa cctgcgtgtt tatgtaaccg gtaataacct gttgactttc
    14101 ggtcctgcca aaaaacgcta cac
//
