LOCUS       c00017_gnlPro..        15072 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNNPFEBK_17.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 11:39:51
            Original ID  :: gnl|Prokka|HNNPFEBK_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15072
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15072
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:5072]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..5072
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15072
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15072
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             3..740
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.1; E-value:
                     6.1e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_1"
                     /sec_met_domain="Fer4_7 (E-value: 3.5e-12, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.1e-09, bitscore: 28.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.1e-08, bitscore: 26.1,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.2e-08, bitscore: 26.1,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.6e-05, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GVHVSGTEDSAYYYSTYNAPDRNPVSVQKPKIMILGLDAAAAEPM
                     VAVVRCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHM
                     NPETGLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRIYVQCVNKDKGAVARKACT
                     VACIGCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKA
                     DDAAPQVKVAAPKAEVETPKAEV"
     CDS             801..2138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_2"
                     /sec_met_domain="Fer4_10 (E-value: 5.7e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.2e-15, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.3e-49, bitscore:
                     158.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.4e-29, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00011, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             2145..3137
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 6.2e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             3164..3799
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_4"
                     /sec_met_domain="FMN_bind (E-value: 6.5e-24, bitscore:
                     75.7, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKEPIAQANAKTLSDAVSAVVPG
                     FDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVLVGFDAEGKII
                     DYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVDAITASTITSR
                     AFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             3741..4400
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 5.6e-71, bitscore:
                     229.4, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNNLLIPQLPKLWIHSALNKKGVEDMNNFKVMMNGIIKENPTFVL
                     LLGMCPTLGTTSSAINGMGMGLATMFVLICSNVVISAIKNLIPDMVRIPSFIVVIASFV
                     TLLQMIMQAYVPALYATLGLFIPLIVVNCIVLGRAEAFAAKNNPVASLFDGLGMGLGFT
                     IALTLLGAVREFLGTGKIFNLSILPEEYGMLVFVLAPGAFIALGYLIALINSMKKN"
     CDS             4488..5072
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.3e-64, bitscore:
                     207.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSLVS
                     VPKGMQGTPIALITAGLLAMAFMGFSGVVKI"
     CDS             5204..6238
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.3e-53, bitscore:
                     173.6, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGKILVTGGTGYIGSHTVVELQNAGYEVVIIDNLSNSSADVVDN
                     IEKVSGIRPAFEELDCLDYAGLDAVFTKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEIV
                     RDTVASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVVAIHRILENKQKEKVEVFNIGTGRGLSVLELINA
                     FEKATGVKLNYQIVGRRAGDIEKVWANPELANNELGWKAETSIEDTLLSAWKWQLKLRE
                     RGIQ"
     CDS             6849..8384
                     /locus_tag="ctg17_8"
                     /transl_table=11
                     /translation="MSQIVGHISQVIGPVVDVYFEGTEAEMMLPSIHDALEIKRSNGKR
                     LIVEVQQHIGENTVRTVAMDSTDGLQRGMTVHPLGGPITMPIGTQIKGRLMNVVGDSID
                     GMKELDRTGAYPIHRDPPKFEDLTTVQEVLYTGIKVIDLLEPYSKGGKIGLFGGAGVGK
                     TVLIQELINNIAKKQHGFSVFAGVGERTREGNDLLREMIESGVIRYGEEFKKGMEEGHW
                     DLSKVDYDEVAKSQVSLIFGQMNEPPGARQSVALSGLTVAESFRDMGAETDGPRDILFF
                     IDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTRNGSITSVQAVYVP
                     ADDLTDPAPATTFTHLDATTVLSRKITELGIYPAVDPLESTSRILDPHIVGVEHYEVAQ
                     RVKQILQRNKELQDIISILGMEELSDADRTLVNRARRVQRFLSQPFAVAEQFTGVPGTM
                     VSIEDTIKGFKMILDGEVDYLPEPAFLNVGTIEEAIEKGKKLLEQAGGKTIKN"
     CDS             8401..8652
                     /locus_tag="ctg17_9"
                     /transl_table=11
                     /translation="MMKKLHLNIVSPEKELFNGEVESVTLPGTMGSFSILPQHAPIVSS
                     LGTGKLIYATDGEEHELDIQSGFVEMSNGRVAVCIEQQ"
     CDS             8694..9113
                     /locus_tag="ctg17_10"
                     /transl_table=11
                     /translation="VTITKRNYLLHTALLTVLIGIVGGWAYFSINPHHYFGGYPLIPLF
                     FFVFGVFMINMTESCRHRMPGRMLQIYLLMRVMRMLVSMIVMLVYCVAVREEARAFLLT
                     FIANYLIYLIYDSWFFFTFEANRKLKKKSNNEKIA"
     CDS             9097..10167
                     /locus_tag="ctg17_11"
                     /transl_table=11
                     /translation="MKRLRNILTVILLALGMLLPATVRAENTVDVKEIVFGHIGDSYEW
                     HITTWGETHVTIPLPVIVHSSTTGWHAFLSSRLEENGGSYEGFSIAPAGSKYEGKLVEY
                     DATGNEIRPLDISITKVTLALLINSALLLLIILSVAHWYRKHPQGSAAPGGFIGFMEMF
                     IMMVNDDIIKSCVGPKYRKFAPYLLTAFFFIFINNIMGLIPFFPGGANVTGNIAITMVL
                     AICTFLAVNIFGTKTYWKDIFWPDVPWWLKVPVPMMPFIEFFGIFTKPFALMIRLFANM
                     LAGHMAMLVLTCLIFISASMGPALNGTLTVASVLFNIFMNALELLVAFIQAYVFTMLSA
                     VFIGLAQEEHKEKAVK"
     CDS             10224..10481
                     /locus_tag="ctg17_12"
                     /transl_table=11
                     /translation="MLLSVLLQAAAAGVGVSKLGAAIGAGLAVIGAGVGIGKIGGSAME
                     AIARQPEASGDIRMNMIIAAALIEGVALLAVVVCLLVFFL"
     CDS             10583..11083
                     /locus_tag="ctg17_13"
                     /transl_table=11
                     /translation="LLLPDSGLLFWMLLSFGVVFVVLAKYGFPVITKMVEGRKTYIDQS
                     LEVAREANAQLSKLKEESEALIAAANKEQGRILREAMHERDKIIVEARKQAEAAAQKEL
                     DEVKKQIQQEKEEAIRDIRRQVAVLSVDIAEKIIRKNLDEKHEQMEMIDRMLDEVLAAS
                     KNN"
     CDS             11095..11655
                     /locus_tag="ctg17_14"
                     /transl_table=11
                     /translation="MDIGIVSMRYAKALMEYAKSMGAEDTLYKEFCMLDRSFRKHPDLR
                     MALENPILTIREKLTLICTAAVGDAPASREFARFMTLVLKNRRENFLQYICLSFLDLYR
                     KDKHIGVGKLITAVPVSQEVRERIHDSASSLLHASMELQTEVDPSIEGGFIFDINDFRL
                     DASIATQLKKVKQQFIDKNRRIV"
     CDS             11785..13371
                     /locus_tag="ctg17_15"
                     /transl_table=11
                     /translation="MLSENIKVSEVSDILRKQLEGIDTRVQLDEIGTVLQVSDGVARIY
                     GLRNAEANELLEFDNGIKAIVMNLEEDNVGAVLLGPTDKIKEGFIVKRTKRIASIMVGE
                     GMLGRVIDPLGAPLDGKGLIGGELYEMPLERKAPGVIFRQPVNQPLQTGLKAVDAMIPI
                     GRGQRELIIGDRQTGKTAIAIDTIINQRANFEAGDPVYCIYVAIGQKGSTVASIVNTLH
                     QYGAMDYTIVVAATAGDPAALQYYAPFAGAAIGEYFRDTGRHALVVYDDLSKQAVAYRE
                     VSLILRRPSGREAYPGDIFYLHSRLLERAAKIISQEEVAREMNDLPDSLKGKVKGGGSL
                     TALPIIETQAGDVSAYIPTNVISITDGQIFLDTNLFNQGNRPAIDVGISVSRVGGNAQV
                     KAMKKVAGTLKIDQAQYRELEAFTKFSGDMDPVTALTIDKGQKNTRLLVQPQYSPMPVE
                     KQIAILYCGTHGLLRNVPLDKVSEFERNFLESLEMNYRMEVLDVLKTGAINDDVCKKIE
                     ETAEAVARQFM"
     CDS             13493..14383
                     /locus_tag="ctg17_16"
                     /transl_table=11
                     /translation="MSSLKEVKNRISSVKSTRQITSAMKMVASAKLHKAQGRIENMLPY
                     QRKLSEILTNFLRTDASFESPYTEKRPVKRVAVVAFSSNSSLCGAFNSNVAKMLERTLE
                     DYQSLGKENILIYPVGRKMEEAVKKMGYVPQGSYQVMADKPSYVEAYELAEKLMHEFVE
                     KQIDHVELIYHHFKSMGSQVLLRENYLPIDLTQVAQEAAEDVPEDARSFNNDYIVEPSV
                     GELIAELLPKVLSQKIFTVLLDSNTSEHAARMLAMQTATDNANELIQDLTKQYNKSRQQ
                     AITNELLDIIGGSLK"
ORIGIN
        1 aaggcgttca tgtcagtgga acggaggaca gcgcttacta ctattcaacc tacaatgcgc
       61 cggatcggaa tcctgtgagc gtacagaagc cgaaaatcat gattctgggc ttggatgccg
      121 ctgctgccga acctatggtt gcggtggtga gatgtaatgg aacttgtgcc aaccgtcctc
      181 gtgtgaacca atacgatggc gccaagagtt gtgccattgc ggcttctctc tatggtggtg
      241 aaacgggttg tagttatggc tgtctgggat gcggcgactg tgtggctgcc tgccagttcg
      301 atgctatcca catgaatccg gagaccggac ttcccgaagt ggatgaggaa aagtgtacgg
      361 cttgtggagc ttgtgccaag gcttgtccga aatctattat tgaaatccgt cctcaaggca
      421 agaaatcacg tcgtatttac gtacagtgtg taaacaagga caagggggcc gtagcacgca
      481 aggcttgtac cgtggcatgt atcggttgcg gcaagtgtgt gaaggtttgt ccgttcgagg
      541 ctatcacgct ggaaaacaat ctggcttaca ttgaccccaa taagtgtaaa tcctgtcgca
      601 agtgcgagga agcttgtccg caaaacacaa tcattgccct caacttcccg ccgcgcaaac
      661 cgaaggctga cgatgcagct ccccaagtaa aggttgcagc tcctaaagct gaggttgaga
      721 ctcccaaagc agaggtttag acttcccaag ttgaggtatg aattaataaa gtaaataaac
      781 gactaaaaat acagaattgt atgttgaaga cattttcaat tggtggagtc catccacacg
      841 aaaataaact ttcagcacat cagcctatca tcaaggcaga gattccggcc aaggccgcta
      901 tcttgctggg acagcacatc ggtgctcctg ccaagcctat cgttgccaaa ggtgatgttg
      961 tgaaagtggg tacaaagatt gccgagcccg gcggttttgt atcagcagcc attcattcgt
     1021 ctgtcagcgg gaaagtcgct aagattgaca cgattgtcga tgccagcggt tacgccaagc
     1081 ctgctatatt cattgacgta gaaggggatg aatgggaaga atccattgac cgttccgaaa
     1141 cgttggtgaa ggaatgcagt ctgacctccg aggaaatcgt gaagaaaatc gctgatgccg
     1201 gtatcgtagg tctgggcggt gcatgcttcc ctacgcaggt caagttgtgt cctcctcctg
     1261 cattcaaggc agagtgtgtc atcatcaacg ccgtagagtg cgaaccgtat ctgactgccg
     1321 accatcagct gatgctggaa catgcggaag aaattatggt aggtgtatcc attctgatga
     1381 aggcggtaaa ggtgaacaag gcattcatcg gcattgagaa caataagccc gatgccatcc
     1441 agctgatgac gaaggttgct tccagctatg caggtatcga ggtggtaccc ttgaaggtac
     1501 aatatccgca gggtggtgaa aagcagttga ttgatgctgt catcagtcgc caggttgcag
     1561 ccggtgcgtt gcctatctcc acgggagctg tggtgcagaa tgtgggtacc gcatttgccg
     1621 tttaccaggc cgtacagaag aacaaacctc tgtttgagcg tgtcattacc gtgaccggta
     1681 agtctctggc aaagccgtcc aatttcctgg cacgtatcgg tacgccgatg aagcagctga
     1741 ttgaagcttg cggcggtttg cccgaagata cgggtaagat tatcggcggt ggcccgatga
     1801 tgggtaaagc tctggtaaat acggatgtac cgacagccaa aggaagctcc ggtattctga
     1861 ttatgaacga gaaggaagcc aagcgcggcg aagtacagcc ttgtatccgt tgtgccaagt
     1921 gcgtgggagc ctgcccgatg gggttggagc cgtatctgct ggctaccgtt tcggcccacg
     1981 gagattttga aagagtagag aaagaagaca ttatgtcgtg tatagaatgc ggttcatgcc
     2041 agttcacttg tccttccaac cgtccgatgc tggattatat ccgcttgggt aagggtaagg
     2101 taggagcgat gatccgtgca cgtcaagcta aaaaataacg aagtatgaat aaattaatcg
     2161 tatccctttc gccccacgtt cacggcggtg acagcgtgaa gaagaatatg tacggtgtgc
     2221 ttatcgcatt gattccggca ttcctcgttt cgctttactt tttcggactg ggtgcgctga
     2281 ttgttacggc aacttccgta gcagcctgct tgttctttga atgggccatc ggcaaattcc
     2341 tcatgaaaaa agagaccaca accatcaccg acggctctgc catcattacc ggtgtgttgc
     2401 tggcctttaa cctgccttcc aacctgccca tctggattat catccttggt gccttgtttg
     2461 ccatcggggt aggcaagatg tccttcggag gtttgggttg caatcccttt aaccctgcac
     2521 tggcaggacg tgtattcctg ttgctttcat tccccgtgca gatgacgaca tggccggctg
     2581 taggccagtt gacagcctat acggatgcca cgacggctgc tacgccgctg gctattatga
     2641 aaggtgtcat caatggtgct ccgggcatgt ccctgagcga ccttccggga gctttcgacc
     2701 ttctgatagg taataatgga ggatgtctcg gtgaggtgag tgctttggcg ctgctgcttg
     2761 gtttgttcta catgttgtgg aagaaaatca tcacctggca cattccggta tctattctgg
     2821 tgacggtatt cgtgttctcc ggtatcatgt atctggtcaa tccggaactt tatgtatccc
     2881 cggtcgtaca gttgttgtcc ggtggtctga tgctgggtgc tgtctttatg gctacggact
     2941 acgtgacttc tccgatgagc cacaaaggta tgctgattta tggtgtttgc atcggcctac
     3001 tgactgtcat catccgtctg ttcggtgcat atccggaggg tatgtcgttt gccattctga
     3061 ttatgaatgc gttcactccg ctcatcaaca cctatgttaa acctaaacgc tttggggagg
     3121 tagcgaagaa gaaatgaaaa agttagaatc atccttgaag aatatgttgc tggtacttac
     3181 gggcgttacc gcaatctccg tagcgttgct ggcttatgta aacgaattga cgaaggagcc
     3241 cattgcgcag gccaatgcaa agaccttgag cgatgccgta agtgcggtgg ttccgggctt
     3301 cgacaatgac cccattgccg agaagaagat gcaggaagta aacggagtac agtattctgt
     3361 atatcctgcc accaaaggtg gagaatatat cggagctgct gtggaagctg ttgccatggg
     3421 ttttggcggt gagctgaaag tgttggtcgg tttcgatgct gaaggcaaaa tcatcgacta
     3481 ctccttgttg tcgcatgtgg aaactccggg gttgggttcc aaggctgccg actggttcaa
     3541 gaaaggcaat aaaggtgaca tcaccggcat gaatccgggt gaagctgcat tgacagtgag
     3601 caaggacggt ggtaaagtag atgccattac agcgtctacc atcacctcac gtgctttttt
     3661 gaatgcagtg aatgcggctt atgctgccta tgccggtcag gaaactgccg acggcactac
     3721 cggcgctact caaaagaatg ttgaacaacc tgctgattcc gcagctcccg aagctgtgga
     3781 tacactcagc gctaaataag aaaggagtag aagatatgaa taattttaaa gttatgatga
     3841 acgggattat caaagagaat cctacgtttg tactcctgct gggtatgtgt cctacactgg
     3901 gtaccacttc ctctgccatt aacggtatgg gtatgggact ggctacaatg ttcgtgctga
     3961 tatgttccaa tgtggtgatt tctgccatca agaatctgat tcccgatatg gtgcgtatcc
     4021 cttcattcat tgtagtcata gcatcatttg tgacactgtt gcagatgata atgcaagctt
     4081 acgttcctgc attgtacgcc acactgggcc tgttcattcc gctgattgtt gtaaactgta
     4141 tcgtattggg acgtgccgag gcatttgctg ccaaaaacaa tccggtggct tccttgttcg
     4201 acggtctggg catgggcttg ggctttacca ttgcactgac attactgggt gccgtgcgtg
     4261 agttcctggg aaccggcaag atattcaact tgagtatcct tcccgaagaa tacggcatgt
     4321 tggtatttgt ccttgctccg ggtgcattca ttgcattggg ctatctcatt gctttaatca
     4381 acagtatgaa gaagaattaa taatgaaaaa ttaaaaatga aaaaattgag aacgtatcgg
     4441 cggtaagctg ccgggctttt aatttttagt ttttaattct taatttaatg attatggaat
     4501 atatattgat atttatctcg gcaatctttg taaacaacat cgtattgtcg caattcttgg
     4561 gaatttgccc gttcttggga gtttccaaga aagtggagac tgcattgggc atgtcggcag
     4621 cggtggcatt cgtgctcacc atcgccacta tcgtgacatt ccttattcag aagtatgtgc
     4681 tcgacgcttt tgatttgggc tatttgcaga ctattacctt tatcctggtg attgccgcat
     4741 tggtgcagat ggtagagatt atcctgaaga aagtttctcc ttctctgtat caggccttgg
     4801 gcgtgttcct gccgttgatt actaccaact gctgtattct cggtgtggct atccttgtta
     4861 tccaaaaaga ttatgatttg ctgacgggag tggtttatgc attctccacg gcacttggtt
     4921 tcggcttggc actgacactg tttgcaggcc tgcgcgagca aatgagcctg gttagtgtac
     4981 cgaaaggtat gcagggtact ccgatagctt tgattactgc cggactgctg gcaatggcat
     5041 tcatgggctt ttcgggggtt gtgaagattt aaagaagaaa aaacggaaat aaagtggaag
     5101 ggggataaac taaaatttat cccccttttt ctgtttttat taatttattt ccttacattt
     5161 gtggcgtatt gataacctaa aagctaaatt atctatattt aatatgaaag ggaaaatctt
     5221 agttacgggt ggaaccggtt atattggttc tcacacggtg gtggaacttc aaaacgcagg
     5281 ttatgaagtt gttattattg ataatttgtc aaactccagc gcagatgttg tagataacat
     5341 agagaaggta tcgggcatcc gccctgcatt cgaggaattg gattgcttgg attatgccgg
     5401 tcttgacgct gtgtttacca aatataaagg cattaaagcc atcattcact ttgcggccag
     5461 caaggctgtg ggtgaatctg tccagaaacc attgctttac tatcgtaata acctggtttc
     5521 actgataaac ctgctggaat tgatgccgaa gcatggagtg gaaggtatcg tattctcttc
     5581 ttcctgcaca gtttacggcc agccggacga acttccggta acggaaaagg cacctattaa
     5641 gaaagctgag tctccgtatg gaaacacgaa gcaaatcaat gaagagattg tacgtgatac
     5701 ggttgcttcc ggtgctccga taaacgccat cttgttgcgt tacttcaacc cgataggtgc
     5761 acaccccaca gcattgttgg gagagttgcc taacggtgta ccgcagaact tgattcctta
     5821 tcttacccag accgctatcg gcatccgtga gaaactgagc gtgtttggtg acgattatga
     5881 tactcccgac ggttcttgta tccgcgactt catcaatgta gtcgatttgg ccaaagcaca
     5941 cgtagtggct atccaccgta tcttggagaa caagcagaag gaaaaagtgg aagtattcaa
     6001 tatcggtaca ggtcgtggac tttccgtatt ggaactgatt aatgctttcg aaaaggctac
     6061 cggtgtaaaa ctgaactatc agatagtagg tcggcgtgcc ggtgatattg agaaggtatg
     6121 ggcaaacccg gaattggcaa acaatgaact gggttggaag gcagaaacaa gtattgaaga
     6181 tactttactt tctgcatgga aatggcagtt gaagcttcgt gaaagaggta ttcaatgaca
     6241 aactttgaat ttgtgttttt taacaaatag gcaataaaca aatgcctccc cgcatttgtt
     6301 tataatgtgc aaatcagcct gaagctgttt atgtatatgt gaatatccgt aactagtacg
     6361 tatgcctccc cggcatagac aggtaagatt gcatagtagt tttgtcgtgt tttattttgt
     6421 gtttgtgttg tgaataagcc ttgtcgagag acaaggctta ttttttgtat attatataca
     6481 gaatctctgt tgtcaattca gtgttttttc ataagatggg taggcaattc ctttttctta
     6541 ctaattgtta actgacgtta tcatgtctgt aacaatttgt tccaattgta gtattaatcg
     6601 ttcaaaatag tcttttttgt tcaaaaaatg ctatacacgg taacaactac atgcaaattg
     6661 tttatacatt tgcgttgttg tttatgtaac tattgggatg aacaaaccat agctgacaaa
     6721 cgttaatagg tacgagtaca tagctgatga aagacgcgac ttggctgact tgttaatgag
     6781 gatacacgcg acttacaact tagtattggg aaaaataatt aaggaaatat agaataaaaa
     6841 gattgcttat gtcacagatt gtcggacata tctcacaggt aatcgggcct gtagtagacg
     6901 tctatttcga aggaacggag gcagaaatga tgttgccgag tattcacgac gcactggaaa
     6961 taaaaaggtc gaacggcaaa agactgattg tagaggtaca gcagcacatt ggtgaaaaca
     7021 cggtgcgtac tgttgctatg gacagtacgg acggcctgca gagaggaatg acagtgcatc
     7081 cgctgggagg ccccatcacc atgccgatag gtacacaaat caaaggccgc ctgatgaacg
     7141 tagtgggcga ctctatcgac ggcatgaagg agttggaccg taccggtgct tatcccatcc
     7201 atcgcgaccc ccctaagttt gaagatttga ctaccgtaca agaggtgctt tatacaggca
     7261 tcaaggttat cgacttgctg gaaccatata gcaagggcgg taaaatcggt ctgtttggtg
     7321 gcgccggtgt aggcaagacg gtgcttatcc aagagctcat taataatatt gcgaagaagc
     7381 agcacggctt ctctgtgttt gccggtgtag gagaacgtac acgtgaaggc aacgacctgc
     7441 tgagagaaat gattgaatcc ggcgttatcc gttacggaga agaattcaag aaaggtatgg
     7501 aggaaggcca ttgggatttg tccaaagtag attatgacga agtggccaaa tcacaagtgt
     7561 ctttgatatt cggtcagatg aacgaacctc ccggtgcgcg tcagtccgtg gcattgtctg
     7621 ggttgacggt ggccgagtcc ttccgtgaca tgggagcgga gacggacggt ccgcgtgaca
     7681 ttctgttctt cattgataat atcttccgtt tcacccaagc cggttccgag gtttcggcct
     7741 tgctgggccg tatgccttct gccgtaggct atcagccgac actggcaacg gaaatgggtg
     7801 ccatgcagga gcgtattacc tctacaagaa acggctccat cacttccgtg caggctgtat
     7861 atgtgcctgc cgatgacttg acggacccgg cacctgccac aacgtttacc cacctcgatg
     7921 ccaccacggt gttgagtcgt aagattactg aacttggtat ttatcctgct gtggacccgt
     7981 tggaatctac ttcacgcatt ctcgacccac acatcgtggg ggtagaacac tacgaagtgg
     8041 cacaacgtgt aaaacaaata ttgcagcgca acaaggaatt gcaagacatt atctccatcc
     8101 ttggtatgga ggaactctct gatgccgacc gtacgttggt gaaccgtgca cgtcgtgtgc
     8161 agcgtttcct ttcacagccg tttgccgttg ccgagcagtt tacgggtgtc ccaggtacaa
     8221 tggtttccat tgaggacact atcaaaggct tcaagatgat tcttgacgga gaggtggact
     8281 acctgcccga acctgctttc ttgaatgtgg gaaccattga agaagccatt gagaagggta
     8341 agaaactact ggagcaggca gggggaaaaa cgattaaaaa ttaaaagtct gggagctttg
     8401 atgatgaaaa agttgcattt gaatattgtt tcaccggaga aggaactctt caacggggaa
     8461 gtggaaagtg ttacattgcc gggcactatg ggctcttttt ctatcctgcc gcagcatgca
     8521 ccgattgtat catcgttggg aacggggaaa ttgatttacg caacggacgg tgaggaacat
     8581 gagttggata ttcaaagcgg attcgtggag atgagtaacg gaagggttgc cgtctgtata
     8641 gaacagcaat aggctattaa aaaattaaaa attaaaaaat agaggttgtt ggcgtgacta
     8701 ttactaagag aaactactta ttgcatacag cgctcttgac ggtattgata ggaattgtag
     8761 gcggttgggc gtatttttcg ataaatccgc atcactattt cggcggttat ccgctgattc
     8821 cgcttttctt ctttgttttc ggagtattca tgattaatat gaccgaaagc tgccgtcacc
     8881 ggatgccagg acgaatgttg cagatttatc tgctgatgcg tgtgatgaga atgctggtct
     8941 ccatgattgt gatgctggtt tattgcgttg cagtacgtga ggaagccagg gcgtttttgt
     9001 tgacgtttat agccaactat ctgatatatt tgatttatga ttcctggttc ttcttcactt
     9061 ttgaggcgaa tcggaaactg aaaaagaaaa gtaacaatga aaagattgcg taacatactg
     9121 actgtaattc tgctggcact gggcatgttg ctacccgcca cggtgcgggc cgagaatacg
     9181 gtggacgtga aggagattgt cttcgggcat atcggcgatt cttacgaatg gcacatcacg
     9241 acgtggggcg aaactcacgt tacgattcct ttgccggtaa tagtgcatag ctctaccacc
     9301 ggatggcatg cctttctatc ctcacgtctg gaggagaacg gtggaagtta tgaaggcttt
     9361 tccatcgctc ccgcaggaag caagtacgaa ggcaagctgg tggagtatga tgccaccgga
     9421 aacgaaatac gcccgttgga catctccatc acgaaggtga cactggcttt gctcatcaac
     9481 agcgcattgc tgcttctcat cattttgagt gtggcgcact ggtatcgcaa gcacccgcag
     9541 ggaagtgccg ctcccggtgg tttcatcggg tttatggaga tgtttatcat gatggtgaac
     9601 gatgatatta taaagagctg tgtcggtccg aagtaccgta aattcgcacc ttacttgctg
     9661 acggccttct tctttatttt catcaacaac attatggggc tgattccttt ctttcccgga
     9721 ggggccaacg tgacgggaaa tatagccatt acgatggtat tggccatctg tactttcttg
     9781 gccgtgaata tctttggaac caagacttat tggaaagata tcttttggcc ggatgtgccc
     9841 tggtggctga aggtaccggt ccccatgatg ccgtttatcg agttcttcgg tattttcacc
     9901 aaaccgtttg ctttgatgat acgtcttttt gccaatatgc tggcagggca catggcaatg
     9961 ctggtgctta cctgcctgat attcatctcg gccagtatgg gacctgcttt gaacggaacg
    10021 ctgaccgtgg catcggtgtt gttcaatatc tttatgaatg cacttgagtt gttggttgcc
    10081 tttatccagg catatgtgtt caccatgctg tcagccgtgt tcatcggtct ggcgcaggaa
    10141 gagcataagg agaaggcggt gaagtgatac gattattggg aatataaata ttaataaaaa
    10201 taaccattta aaaactgaaa gttatgttac tatctgtatt attgcaagct gctgcggcag
    10261 gtgtgggagt tagtaaactg ggtgcagcca ttggtgctgg tttggctgtt attggtgctg
    10321 gtgtaggtat tggtaaaatc ggcggttctg ctatggaggc cattgcccgc cagccggaag
    10381 catccggaga tatccgtatg aacatgatta ttgccgctgc cttgattgaa ggtgttgctt
    10441 tgttggcagt agttgtgtgt ttattggtat tctttttata atgtacaatc taccatttac
    10501 catttacaat ttgtccgtgc agcatcaccg cgcagccaaa ttgtaaatcg taaattgtca
    10561 aatagtaaat aaaattatgt cattgttatt acccgatagt ggtctgctgt tctggatgct
    10621 cctttcattc ggtgtggtgt ttgtggtgct tgccaagtac ggttttcccg ttatcaccaa
    10681 gatggtggaa ggtcgcaaga cctacatcga ccagtctttg gaagtggcac gcgaagcaaa
    10741 tgcccagctc tccaaactga aagaggagag tgaagcgttg attgctgctg ccaacaaaga
    10801 acaaggacgt attctgcggg aggcgatgca tgagcgtgac aagattatcg tcgaagcacg
    10861 caagcaggcg gaagccgccg cgcagaagga gctggacgaa gttaaaaagc agatacagca
    10921 agagaaggaa gaggccatcc gcgatattcg ccgccaggtg gcagtcttgt ccgtagatat
    10981 agccgagaaa attatccgca agaatctgga cgagaaacat gagcagatgg agatgataga
    11041 ccggatgctg gatgaagtgc tggccgcaag taaaaacaat taattctcaa agaaatggat
    11101 ataggaatcg tttcgatgcg ttatgcgaaa gcattgatgg aatatgccaa gagcatgggg
    11161 gcagaagata ctctgtacaa ggagttttgt atgctcgacc gtagcttcag gaaacatccc
    11221 gatttgcgca tggcattgga aaaccccatc ctgacgatac gtgagaagtt aacacttatc
    11281 tgtaccgctg ctgtggggga tgctcctgcg agccgtgagt ttgcgcgttt catgaccctg
    11341 gtgttgaaga atcggcggga aaactttctc cagtacatct gcctgagttt tctggatttg
    11401 taccggaaag acaagcatat cggtgtagga aagctgataa cagccgttcc cgtcagccag
    11461 gaagtgcggg agcgcatcca tgacagtgct tcctccctgc tgcatgccag catggagctg
    11521 cagactgaag tggatccctc cattgaaggt ggttttatct tcgacatcaa cgacttccgt
    11581 ctggatgcca gtattgctac gcagcttaag aaagtgaaac agcagttcat tgataagaat
    11641 agaagaatcg tgtgatttac gatttgacaa tttacaattt actatttaat agtcttgtga
    11701 tgcgtaagtt gtagaggtca aacagtatat gattcgggtt ctttcaaata gtaaatagta
    11761 aatcgtaaaa tagtaaatac taagatgttg tctgaaaata taaaagtaag cgaagtctcc
    11821 gatattctcc gtaagcaact ggaagggatt gacacccgcg tacagttgga cgagattggc
    11881 acggtactgc aagtcagtga cggtgtagcc cgtatctatg ggttgcgcaa tgccgaagcc
    11941 aacgagttgt tggagttcga caacggcatc aaggccattg tgatgaacct cgaagaggat
    12001 aatgtgggtg ctgtgttgct tggccctacg gataaaatca aggaaggctt cattgtaaag
    12061 cgtaccaagc gtattgcttc catcatggtg ggagagggta tgctgggccg tgtaatagac
    12121 cctctgggtg cgccgctcga tggcaaagga ctgataggcg gagaacttta tgaaatgccg
    12181 ctggaacgca aggcgccggg agttatcttc cgtcagccgg tgaatcagcc gctacagacc
    12241 ggtctgaagg ctgtggatgc catgatacct attggccgcg gacagcgtga actgattatc
    12301 ggtgaccgcc agaccggtaa gacggccatt gccatcgata ccatcatcaa ccagcgtgcc
    12361 aattttgaag ctggtgatcc ggtgtattgt atttatgtag ccattggtca gaaaggttct
    12421 accgttgcct ctatcgtgaa taccctgcac cagtacggtg cgatggacta taccattgtg
    12481 gtggctgcta cggcgggcga cccggctgca ttgcagtatt acgctccctt tgcaggggct
    12541 gccatcggag agtatttccg tgataccggc cgtcatgcgc tggtggtcta tgacgacttg
    12601 tccaagcagg cggtggccta tcgtgaagtg tctctgattc tgcgccgtcc atcaggacgt
    12661 gaggcctatc cgggtgatat cttctatctg cactcccgtt tgttggaacg tgcggcgaag
    12721 attatcagcc aggaggaagt ggcacgcgag atgaacgacc tgccggacag tctgaaaggc
    12781 aaggtgaaag gtggcggttc gctgactgca ttgcccatta tcgaaactca ggcaggagac
    12841 gtgtctgcct atatcccaac gaatgtgatt tcaatcactg acgggcagat attccttgat
    12901 acgaacctct tcaaccaggg taaccgtccg gccattgacg tgggtatctc tgtgagccgt
    12961 gtgggtggta atgcccaagt caaggctatg aagaaggtgg caggtacatt aaagattgac
    13021 caggcacagt accgggagct ggaagcgttt accaagttca gtggcgatat ggaccccgtg
    13081 acggcattga ccatcgacaa gggacagaag aatacacgcc tgctggtaca gccccaatac
    13141 agcccgatgc cggtagaaaa gcagattgcc attctttatt gcggcacgca cggcttgttg
    13201 aggaatgttc ctttggacaa ggtcagcgag tttgaacgca acttccttga gtctcttgag
    13261 atgaactatc gcatggaggt actcgacgtt ttaaagacgg gtgccatcaa tgacgatgtc
    13321 tgcaagaaga ttgaggagac ggcagaggcg gttgcaaggc aattcatgtg atttacgatt
    13381 ggacgattta cgatttacga ttggagttac tctatatggt aagttgtaaa tcggacgcag
    13441 gcagaagtta cctcaatcgt aaatcgtaaa taattaaatc gtaaatagat atatgtcttc
    13501 actgaaagag gtaaaaaata gaataagctc cgtcaagagt acacgccaga taacatcggc
    13561 tatgaagatg gtggcatctg ccaaactgca taaggcgcag gggcggattg agaatatgct
    13621 gccttatcaa cggaagctga gtgagattct gacgaacttt ctgcgtacgg atgcttcctt
    13681 cgagtcgccc tataccgaga aaagacccgt gaagagggta gcggtcgtgg cgttttcgtc
    13741 caatagttcc ttgtgcggtg cattcaactc gaatgtggcg aagatgctgg aacggacttt
    13801 ggaagattac cagtcgctgg gcaaggagaa tattctgata tatcccgttg ggagaaagat
    13861 ggaggaagcc gtcaagaaaa tgggatatgt gccgcaaggc agctaccagg tgatggcaga
    13921 caagccttcg tacgttgaag cgtatgagct ggcagagaag ttgatgcatg agtttgtgga
    13981 aaagcagatt gaccatgtgg agctgattta ccatcacttc aaatcgatgg gttcgcaggt
    14041 gctgctccgc gagaattatc tgcccattga cctgacgcaa gtagcgcagg aggcggcaga
    14101 agatgtaccg gaggatgccc gcagttttaa taatgattac attgtggaac cttccgtcgg
    14161 cgaactgata gcggaacttc tgccaaaagt gttgagtcag aagatattta ccgtgcttct
    14221 cgattccaat acttcggaac atgctgcccg tatgcttgcc atgcagacgg cgacagataa
    14281 tgccaacgag ctgattcaag atttgacgaa acagtataac aagagccgtc agcaggccat
    14341 tacgaatgag ctgctcgata ttatcggcgg tagcttgaaa tagtccggat tgcctcgtaa
    14401 agggctttct taggatgggt acaaataaat ggaataatag gacaaggata acgaaataac
    14461 cgctatcttt gtcctattat catatatggc tactgatgaa atccgtatca ttctgagaga
    14521 gagcggattg gttgaataat aaacatatca atggagaata atcccgaaat agcgcttgca
    14581 tggcaattca ttgaaaacac aggcactcat ctttttttga ccggcaaggc aggtaccggt
    14641 aagacaactt tcctgcgaaa actgagggca gagagtccga aacggatgat tgtacttgca
    14701 ccgacgggaa ttgccgctat caatgcaggc ggtgtcacca tccactcttt tttccaagta
    14761 cctttcgctc cttatgtgcc cgaaagctca ttcagcgcag atggcaaggc aacctaccgt
    14821 tttcgttacg ggaaagagaa aatcaacatt atacgcagca tagatttatt ggtcatcgat
    14881 gaaatcagta tggtccgtgc cgacttgctc gattcggtgg atgccgtctt gaggcggttc
    14941 cgcgaccgga acaaaccctt tggcggcgtg caactgctga tgattggcga cttacagcag
    15001 ctgtctcccg tagtgaaaga cgatgagtgg cagatgctgc gcaaatacta tgacacgcct
    15061 tatttcttct cc
//
