LOCUS       gnlProkkaKPIIPBHD_320   3650 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KPIIPBHD_320.
ACCESSION   gnlProkkaKPIIPBHD_320
VERSION     gnlProkkaKPIIPBHD_320
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 04:46:26
            Original ID  :: gnl|Prokka|KPIIPBHD_320
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3650
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3650
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1:3136]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..3136
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..3650
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3650
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(2..1078)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.3;
                     E-value: 1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg320_1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3e-21, bitscore:
                     63.9, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-21, bitscore:
                     64.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPT"
     CDS             complement(1095..2396)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg320_2"
                     /sec_met_domain="CTP_transf_like (E-value: 6.1e-14,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 6.3e-122, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 7.1e-64, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(2417..3136)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg320_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-17, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(3200..3649)
                     /locus_tag="ctg320_4"
                     /transl_table=11
                     /translation="MYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDN
                     VVLQSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSG
                     MGLKIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
ORIGIN
        1 tcgtgggacg tcccaaattc tcccgagaat ctattttaac ctttatttcc aacaaaacag
       61 gaccacataa ctttggaagc tgcttcattg cttcttcaat ttcaactttt gtacaaacag
      121 tataagtatg cttatatccg ctcccccgga caatagccgg aatatctaaa ctaaatccta
      181 aagtaggctg tcctcctaca gactcgtgag caccattgtt aaacaaaata tgataatagt
      241 ttttaggaga taaatcgcca atgttactaa ttgcccctaa atgcataata aatgctccat
      301 caccatccaa gcaataaaca ggtctatctt gctttgctat agcaataccc aaagagattg
      361 atgaactatg tcccatagag cctaccgtga gaaaatcatg ttcatgacct tgctctttca
      421 tttctcgata ttcaaataac tcacgagaaa gcttgccagt agtagaaacg accactgaat
      481 tttcaggcag ataatccaca actatttgca aagcatcctc acgagataaa ggataattac
      541 atccgaactc tttttgaagt ttatatttgc caaaaacatc tttccgaata attattgcat
      601 gaggaatatt cttagttttt gctgattgta tgatatcatg gagctgaata aatgcatcat
      661 tctcatttga atcaagaatt atataaggaa tccgcattgc tttcaacaaa tctaaagtta
      721 cctcaccctg ttttttatgc tgaggttcat cttttgttcc cggttcacca cgccagccaa
      781 tcatcaaaag cattggaaaa ctgtatactt gttcatctgc aagagacagc agaggattaa
      841 cagtattacc caagccggaa ttttgcatat aaaccacagg aaccttacct gatgccatat
      901 aataacctga agcaattcct acagccgcac cttcattagc agctatgata tgtttctcac
      961 gtgaagtatg gtctgtgata taggcacaaa tattttttag taatgagtct ggaactcctg
     1021 taaaaaaatc aacgtcatga ctcagaaacg tttcataaac tttttctacg cttaacataa
     1081 tgatattcct ctttttattt agtacctgga atcagttcca atatttcttt tatgggcata
     1141 cacagttcgc gcacctctaa agcacgttca ttctctaata ttatctttgc gacattcatc
     1201 atagcaggat aagcggcacg aagcatatga ttagcataaa taattatatt cacaccccaa
     1261 tcacacaatt cagactcata aatatgatca tatgtagtag gcacaaccac gataggtaca
     1321 tgagcatact gttttcgaaa cgccaaacaa aattctttta tatcttcacc cgacttattt
     1381 ttgctatgta tcataatacc gtccgctccc gcttggacat atgcaaaagc tctctctaaa
     1441 gcatcactta ccggctttcc cgctataagg ctctcaatac gagcgataat cataaaatca
     1501 tcagtaatct gagatgcctt tcctgctttg atcttattac agaaaccttc gattgtatct
     1561 tgagtttgaa taacatctgt accaaacaat gaattctttt ttaatccaac tttatcttca
     1621 attattatag ctgaaattcc atgacgttct aaagtgcgta ctgtaaatac gaaatgttca
     1681 attttaccac ctgtatctcc atcaaaaata ataggtttag tagtacactc cagaatatta
     1741 ttcaaatctt gcaatcgggt agttaaatca accgcctcaa tatcaggttt acctttactg
     1801 gttgaatccg taaggctact agaccacatt ccgtcaaata cttccctctt atcccctttt
     1861 aatatttcct gattttcaat tatcaagcca catagtccat catgagcttc caaaatacga
     1921 actacgggtt tggcatttat caaacgacga agtgatttta aacgtacatc aggggttgta
     1981 cctatagcct taatatcttt atccaaagaa gatgaattaa ttcccaaagt atatggaatt
     2041 tcgataacct ttcctccctg ttcattcatc acttcaaata cgcgcacacg ttcttcacgt
     2101 aaaggcccgg ttttccagtc gtcaccatga attatatagt caggtttaat gcgtttgaga
     2161 ttctcaacat agctccattc ttcttgagga acaactttac atacgccttt aatattctga
     2221 actacctctt ttcgttgttc ataggtcaga taaggaaggc gtttatgctc cgcaatagct
     2281 ttatctgtaa gaagaccaat tataacatca ccgtatttag tagcctcatt aataatgcgg
     2341 ataagtcctg gatgcataat atccgcagtc atcccaatat aaactgtctt actcataatt
     2401 tgatatatta ttttaattaa caatacggaa caatatattt ctctgcatat tccaaatctg
     2461 atatgtcatc gatttcatac catttcagcc cttctacttt atgcacataa acaggagatt
     2521 gagaacaaga tattcgtagt aattcatact catatcccaa attgggttgt tcatcaacaa
     2581 tactcgcata atcagcacac attattttgt aaaaggaacc ggatagttta tggatgccga
     2641 ccaattcgcc tttagcgttt agtttattct tattgacaga acatgaagaa aggcgaaaat
     2701 tatcatcatg ttccacataa tactgatctt gaaactttgt cactggagct attagcattg
     2761 catctgccgc aggacactcc aataagctca ttattgcttg tttctcaaaa atcaaatctg
     2821 actctaacaa taaaaaatca tcattgccca gaatctcccg cgtattatat aaagtataca
     2881 tactatttgt ttcagcataa cgaggactaa aacaggtttc aagcatagga tagtctgtct
     2941 tcaattcttc ataaacttct tgtttatatc ctgtaccgat tacaattcgc tcaatgccac
     3001 atgataacaa agtatcaata gaacgaacta tcattggaat acctcccact ttgacgaacc
     3061 ctttaggtat caattctgta tattggccaa aacgggttcc catgcccgca gccattatca
     3121 tagctgtacg tatcattcgt ttaataatat agtaagtgaa tttaattgat gtaagaatgt
     3181 tgtaaacgac gttttagcat catttatcct gttctatctc cttatttttc agttcttttc
     3241 tcaagctagc cagcagactt ttgccaaaaa acacccacac gagagtacca gatacggaca
     3301 ggaacacaaa taataaaata taaattttga gtcccatacc tgaaggtttc aaaggtacaa
     3361 cggcaggctc aactactgca aagactggct tttcctcctg tactttggct ctggatacct
     3421 gcaactgatt agcaacctga ctatatatct gataagccaa actcatgtcg ttctgtaaac
     3481 gctcctgctc agcacgtaca ctttgaagaa ccacattatc atgggcgtct acataatccg
     3541 catattttct ttgagcagca taatattcct gctgacgttc tttaaacaac cgttccaaat
     3601 acgcacagtc ttcttttact tttgaagttc gatacccaat aatatattcc
//
