LOCUS       c00044_gnlPro..        12937 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LIOOBEFL_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 13:38:52
            Original ID  :: gnl|Prokka|LIOOBEFL_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2402
            Orig. end    :: 15339
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12937
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12402:15087]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12685
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12937
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12937
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             123..251
                     /locus_tag="ctg44_5"
                     /transl_table=11
                     /translation="MKNIAILAIAGAACLVASCSQQQQQQQTTAPAPAPVVQAKGK"
     CDS             complement(461..1168)
                     /locus_tag="ctg44_6"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQPYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWDEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPMLVQRIF
                     QSDQQNEAKAAAE"
     CDS             1291..2901
                     /locus_tag="ctg44_7"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             2965..3483
                     /locus_tag="ctg44_8"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             3612..4358
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_9"
                     /sec_met_domain="adh_short_C2 (E-value: 7.3e-76, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             4382..5587
                     /locus_tag="ctg44_10"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPVA
                     GSSLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIIRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             5601..5801
                     /locus_tag="ctg44_11"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             5913..6047
                     /locus_tag="ctg44_12"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGRYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(6265..7005)
                     /locus_tag="ctg44_13"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7300..8007
                     /locus_tag="ctg44_14"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTNRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8436..8753
                     /locus_tag="ctg44_15"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDXXXXLEGRTLRRAAGGTNGTTLSGTSGTV
                     P"
     CDS             complement(8710..9495)
                     /locus_tag="ctg44_16"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARNVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLVLTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg44_17"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_18"
                     /sec_met_domain="SucD_FumR (E-value: 8.3e-14, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12685
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 168.5; E-value:
                     8.8e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_19"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-52, bitscore:
                     168.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.8e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVXXXXAKGIVTRNLVTGE
                     IKSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPV
                     KGDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSF
                     GNLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEE
                     ITDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALR
                     QGLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSF
                     HRELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVA
                     DFLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVL
                     HKEPLTFENVHLAIRSYK"
     CDS             12726..12935
                     /locus_tag="ctg44_20"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDRSEEHTSEL"
ORIGIN
        1 tgccgtgaca tggaacaaga aaatctcttg atttctactt gccaccattt acattggtgc
       61 cagcaaacct ccgtggatgc ggaggttcca gtagttaaca aacactgtat ttaattcgaa
      121 ttatgaagaa catcgctatc ctcgccatcg ccggcgccgc ttgcctggtc gcttcctgct
      181 cccagcagca gcagcaacag caaaccaccg ctcctgctcc cgctccggtt gtgcaggcca
      241 agggcaagta agtttgcagc ggggttttgc cctgcaacac tagcaaatta tccaattaat
      301 ccgcactcgg tgtacgcact gagtgcgttt ttatttgccc tgagtccgga ttccctccgc
      361 catttgccga ttcgccggga ttttccttaa aaacggagga taccgcaaac cgccgcggcg
      421 cagcaccgtg tgccggttcc tgccggatca ggcttcccct ttattcagcg gccgccttcg
      481 cctcattctg ctgatcggac tgaaatatcc gctgaaccag catggggcgt ttcctggccc
      541 acccgggcca gaccaggtga tgttccatgc cgtaggaatg gccctccgga aaggccttgg
      601 aaacaaatgg ttcccgccag tcctcatccc atttgccgcc ttcccggtcc ttctgggtca
      661 gcgtcaccag atgcccgcag ttcttccagg catccagaac aatggagccc tgcaatccct
      721 tccccgcggc attgacatac acgcaactgt gctccctgcc cgttcctcgg tctcgaatcg
      781 tcagccctat gcggaaatac ttcacggggc ggcggcgcag gtcccggtac aaatcctgct
      841 ggacctgcca gcacagcccc ctgtcgcgca ggttggaatt gaccagaata ttgttcagcc
      901 agccaaacag cacagtcctg ttgtcccggg caatcgcggc ggactggacc acggccgtgt
      961 ccgccagcca cctggcctcc gctccggcag cgggaagaga ggcctgatcc ggcggcagca
     1021 gcgccaggaa ggcattagcc agcccggaca tttgctgctg cacgtaaggt tgttgtatat
     1081 aatcctccgc cggaggagta cagcaggaac tccatccgca caaaagggcg gcagcaagca
     1141 aaagcctgaa tgtctgcgtg gtcggcatgg cgcgccaagg ctagcaaact acgcgtaaaa
     1201 atccagtaaa gctttcaaaa atgcctgcct ccgccctgac ggctcttgcc ttcccctttc
     1261 catcccggta gaatacatcc tctcttcacc atgctgacga tcaaaaatct cacaaaatcc
     1321 cacgccggac ggaccttgtt cagggaaacg gaaatgacca ttaactgggg ggaacgggtg
     1381 gctctggttg gccccaacgg agcaggcaaa tccaccctgt tccgcatgat tctgggagaa
     1441 gacacgccgg acgaaggctc catcagcatg gatgaatacg ccatcgtggg ctatcttccc
     1501 caggaagcca gcgaaccgaa ggatgaaacc gttctggaaa tcgccctggg catcacgccg
     1561 gaaatggaac aggccatcca caccatccgg acggcggaaa acgccaacaa aacggatacg
     1621 ccggaatacg cggaagccat tgacactttc aacgccgcca acggttacca gctggagccc
     1681 aaagccaaga aaattctcaa agggctggcc tttcgggaaa gcgacttcca tcgcccagcc
     1741 cgggaaatgt ccggcggctg gatcatgcgc gcgtacctgg ccaagctcct tgtcctggag
     1801 ccggacctcc tgatgctgga cgaacctacc aaccacctgg acctcctgtc cctgctgtgg
     1861 ctccagcgat acctgaaaaa ctaccccgga gccatcctga tgatttccca cgaccgggat
     1921 ttcatggatg agctggtgga aagcgtgtac gacatcgaca acgaagaact ggtggaatac
     1981 cgcggcaatt actcggactt cctccaacaa aaggacgtgc gcttcgagca gcttcaggcg
     2041 gcctaccgca accagcagaa ggaaatagcg cacattcagg aatttattga ccgtttccgc
     2101 tccatcaatt ccaaagccgg gcaagtccag agccgcatca agcagctgga aaagatgaaa
     2161 atcattcaaa aaccggtagc ccgcaggaaa gtatttaaat tcaacttccc ccagcctccg
     2221 cgcagcaccc agaaagtcat tgagctggaa aaagtctgcc aatcctatgg cgaccgcagg
     2281 gtttatgaaa acctggacct gctggtggaa cgcggggagc gcactgttct tgtaggcccg
     2341 aacggcgcgg gcaaatccac tcttctcaaa atcctggcgg gcatcatccc cattgactcc
     2401 ggacaacgca ctcccggtac cacgacgcgc atcggctact tctcccaggc gcgaacggaa
     2461 aacctgaatc cggaaaatac cgtgctggag gaaatcatga aatgcagcgc tgaaatccgg
     2521 gaggaagaag cgcgttccat cctgggttcc ttcctgttcc ggaggctgga tgtggaaaaa
     2581 cgcgtcagcg ttctttccgg cggggaaaaa tcgcggctca gcctggtcaa attcctggtg
     2641 gatccgccca acctcctgct gatggacgag ccgaccaccc acctggacct tttgtccgta
     2701 gaagccctgg tgcaggctct gaagcattat gaaggaacac tggtcttcat ctcccacgat
     2761 gtgcacttca tccgttccct ggcacaaaaa accctgcatg tgaaccgggg gaccatcacc
     2821 gcctacgcag gtggatatga ctactatctg gaaaagtcag gcattctgga cgatgaaaaa
     2881 ggcggcatca cagcggaata aggctctttt ttcagtttcc cctttttcct tgccgtggat
     2941 ttcatcctgc cttaaaagaa caggatgaag gcttttcttg ttcctctctt atattctgcg
     3001 cttctgtccg gagcctctct tgcatttggt gaaacggccg ccggaacggc ttcccccgca
     3061 gcagcggctc cggcggaaaa aattccttcc gcggaatccc tgatcaacca ggccttttcc
     3121 tttgccatca atatccagca gacgttggca ggcgttcagg acaaggaaag cgcggacaac
     3181 gccgtcaaaa cgctgcagga cattcagaag gacatccggc atttcctcca gcttcaggat
     3241 aaattgaacg atgcggaaaa ggagaaagaa gacgccttga tagaaaaaat ggaaaaacga
     3301 atggaaatgc tggacaaccg ctgcaggcag gaaggcaaac gcctgtttga ggcccgctat
     3361 tacggttccg ccgccttaaa ggacattttg gaaaattcgg atgaattcag cgacctggta
     3421 gaaccggatg aagacggggc gccccccggt gcactccggg aaaatgaaga ggccggacag
     3481 tagccccccg ccccgtttct ccccccctct tttttcattc ccggcacgcc ccttccccgt
     3541 atgggttcct gcgcggccaa gtccatttca agcttgccga aaccgtgaaa aacgggttta
     3601 ctgtgggcag catgcaaaag ttagcaggta aaacagccat cgttaccggc gcgggccgcg
     3661 gaatcggcaa tgccgtcgcg cgccgcttcg cttcggaagg agccagggtc atcctgatca
     3721 gccgcagtcc atccagctgc gggggggccg cagaagaaat caacaaggaa tttccggatt
     3781 cctgcaaggc ctacccctgc gacgtagcgg attacgcggc cgttcaggaa accatggccg
     3841 ccattttgaa agacttcccg cagattgaca tcctggtgaa caacgccggc atcacgcggg
     3901 actccctgat gctccgcatg aaagaggaag actgggatgc cgttctggac accaacctga
     3961 aaagcgcgtt caatacggtc aaggccctcc agcgcgttct catgaaatcc ccggccgggc
     4021 gcatcatcaa catgagctcc gtcatcggtc tcgtcggcaa catcggccag gccaattacg
     4081 ccgcttccaa ggcgggcctc atcggtttca ccaaatcact ggctcaggaa ttcgctccgc
     4141 gcaaagtcac gtgcaacgcc attgctcccg gcttcatctc cacggaaatg tccaatgcca
     4201 ttcccgacaa tctcaaggaa gaaatcgtta agaaaatacc tttgaaagaa caaggttccg
     4261 tggaagatat cgccgccctg acggccttcc ttgcctctga cgatgcccgt tacatcaccg
     4321 ggcaggtcat tgcctgcgac ggaggcatga cgatgtaggg cattccggtt ttctccattc
     4381 catgcgcggc attttccttg tttcctgctt tctgggagga agcgccctgc tggccgggtg
     4441 ccgggaagaa aataattccc cccgcccggc cacggaagat gccgcgcgca ttaccagcgc
     4501 acgccagtgg ggagaaagcc gatccgcgct gcaaaaacgg gaactggacc gcgctgccgg
     4561 tcctgccctt cccattccgg atgacctgcc gtcccgggag ctggtcggca caacgcgcca
     4621 aatccatcag ctcattgaag cttccggaaa tccggcacgt tttgaatcct acacggaaac
     4681 ggttcccgtg gcgggatctt ccctgcgcat ggtcgccata ccgggaggaa cgttcctcat
     4741 ggggagtccc gcggaagagc cgcaccggaa accggacgaa ggtccgcagc ataaagtgag
     4801 catctccccc ttctggatct cggaaacgga aatcccctgg gaactttata cggccttcat
     4861 ggaaaacggg cgtccgcgcg ccaaggacgg ccagcttctg gaggaacagc cggatgacga
     4921 actgtgggac tccgttacgc agcctaccgc cccctacacc gccatgaacc tgggcatggg
     4981 ccacggctat gaacacggtc tgcccgccat ctccatgtcc caccacgccg ccagcaaatt
     5041 ctgcgaatgg ctgagcgccc agaccgggca ttactaccgc ctgcccacgg aggcggaatg
     5101 ggaatacgcc tgccgggccg gctcccccgg cgcctattct tacggaaacg gggaagcctc
     5161 tctggaccag tacgcctggt actggaacaa ctccaatgac cgctatcaga aaacaggctc
     5221 taaaaaacca aataagtggg gactccggga catgcacgga aatgtggcgg aatgggtttt
     5281 ggactcttac gttccggatg cctacggcaa acggagcggc ttgcccgcga aagacccctt
     5341 ggtcatcatc cccggcgccc ctcacatcat tcgcggcggt tcgtgggaag acgacccgga
     5401 cagcctgaga agcgctgcgc gccgcgccag cacccccgcc tggaaccgtc aggatcctca
     5461 aaaccctaaa agcatctggt acctgacgga cggaggcatg atcgggttcc gcgtggtgcg
     5521 ccccatgaac attccggaca ttatgacgat gcaccgcctc tggaatttct ccaaggggga
     5581 gccgtaaaga acaacctttc atgaccattg cattaagaac ggaacaatcc tcagaccatg
     5641 ccgaaacgga acatgtcacg agagaagcgt tctggaacta tttcgtcccc ggctgccatg
     5701 aacattacct gctccatatc atgcgcgtca gtccgtcctt catcccggag ctggatgcag
     5761 tcgccgtcca cggcagccgc atcgtcggga aacatcgttg atgcaacgtc cgtcatcagg
     5821 gcagacgatg gaaaagaata tgaagtgctg ggcatggggc ccattgccgt tcttccgaaa
     5881 taccagcgcc ggggaatagg acggcgaata atatgtatgc ggcggccctc caggtctgtg
     5941 agctgcaaag gggttcccta tccggcctga aaggccgcta tgtgaaagct gccgtgtacc
     6001 atatggacga aaagcgcgct gccgaatttg acggcatttt ccggtaaaga aaaagctttc
     6061 cggtactgcg tctcaaaaac gtttccagca aattgccgcc atgccgaaaa aaccggatac
     6121 ggccccctgc ccccggaaat tccgtacctt ccggagggca taaatcccgc atacggataa
     6181 gcaattcttc ctctctggat ataaaaaaca agagctgttc cgcaagaaca gctctcatcc
     6241 gccgattttt cgccatcagg aagctcaagc cctgcggcgg cgcatcatca gcgcggccag
     6301 tcccagcagg cccagggaaa ccgtggcggg ttccggcacc atttcccctc ggatttccgt
     6361 gaaaatcggg gataataagc tgaaagtatt ggttccgttg gctcccgtaa taacgacaga
     6421 atcaccaggc gctccctcgg cgtcataatg gccgcggatg ccgggagcag tcaatccgcc
     6481 gctgatcgtt acggtatctc cttccgtgtt agcagtaggg gcggctgttc cccccgcagc
     6541 atataaatac gttttagacg tatcctgcat caagtccatc acggactggc tcacggccag
     6601 gaaacggtat gtcaatgccg cgtcaagaag caggggagaa ccatccaggg aagaaaaact
     6661 gaacgtcaga ttaatccctg ctgcagtagt tcccgtattg gtgctccagc cgatgaccga
     6721 attgtcggag ccattcagca ccaggaagcc gtaagtgaca ttagcgccca aattgttggc
     6781 ggctccgcgc agcgtaaaac tgtccagtct gatctctccg gacagggagg agggagaaga
     6841 ggaatcggaa ggagccaggg aagaagaccc caggccaaga taaaacccat ggatggtact
     6901 attgtaatta tccgtaccgg gagtgtaata attaaaaacg gtcgctgcct ccgaggaaac
     6961 agcaaagctt cccatcgcga ttaaaaatgt cagtgttttc ttcatattta ttattccttt
     7021 tggatggcaa cttgtagcga atttggaatt ccccaatcgg atttggaatc cgtcaagtaa
     7081 tgaaaaagag gccaaatcaa tcatgaaacc aatgaataac aaagattgcc ccgtcatctt
     7141 gacaaaagga ccagagatat taaaaaatca ttattttcaa tgaattataa atacaatata
     7201 ctaactctta atatttttaa ttgcttgcgg attccaaatt cgttattcaa gcgcaagtgc
     7261 atacattgaa tcttgcatca ttttattaag atactgacca tgaagaaatt attatccacc
     7321 ctgattcttt cggccggcat gagcctgagc gccaccgcga ataccactct gctggatagc
     7381 tctatcgtgg gatattcgga ctttacctcc caaacggcgg atttcggcac cctgaaagat
     7441 tccgtttcca tcacgtctga cgacagcaat ctgacgttat ccgggataac cttcaacgga
     7501 tacggtacca acaaccgcga cgttatgtct gtgacgatgg ttcttgatct gtccaaaatc
     7561 aacactccgg agacctatac cgctctgttt aacgccaaaa acagcagtgt aagctggggc
     7621 gtgggcctga acacgaaccg gaaactccag ggattatgga acaacacctc atacagcggg
     7681 cccgtcgttg acaccccgct gggcacggaa gggtccctga ccatttccgt agtcaccgga
     7741 gatcttggca cccgcatcta ttttggcgac agcgctacgt actattccaa cagcggcctg
     7801 aaattcggca accagcaaat tgatcagatt ctcatggacg caggactggc tgaatccatc
     7861 gaacagctct acatccacga ctccctcctt tcccaggaac aagttggtca actgatgagt
     7921 gaaatcgcca gcattccgga acccgccacg gcttccctgg gcctgctggg actggccgcg
     7981 ctgatgatgc gccgccgcag ggcataagcc tgtaccgtcc gcctccctat attcaaaggc
     8041 cggctcacaa aatcgtgagc cggccttttc cttatccgtt caaacatctg ccgaaaaaac
     8101 agaggggaaa agcttccatt tgctgcggca acctcacggc cagcacttga cggaaaaatg
     8161 gcattcagtc tcccccggta gggtcatttc aagagcttcc ggccccgccc cacttccgta
     8221 cacgcccctt tttcccatgc cgggacagcc ggaaccggag catgcaaagc ccggcttccc
     8281 tcagcatccg gaacagccca tcctttcagc aatccatttc cccgcacggt ccggatcgct
     8341 gcggttccgt ccgtcggcaa cagactcctt ccccgaaaca gggaaaagga gtgggaaaat
     8401 ggctgagctt gaacctttat cccccgttcc cgtccatgaa ccttcaaaaa cagcagctgc
     8461 tactgcgcct gttccggtat ttcaaaagca gaaaaggaga accgcgtttt ttcaacaaac
     8521 ggaatatatg ccttctggcc gccgccggcg cctacatcct gactcccgac gaattcctgt
     8581 ttgacggaat cggcaggctg ggccttctgg atgacgcggc ggtcatcctg ggcgccgtcc
     8641 tcaccgtctt tttcccggac gnnnnnnnnn nactagaggg ccgtaccctc cgccgcgccg
     8701 cgggcggaac taacgggacg acactttccg gaacttcggg gactgtccca taaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgcagctc
     8821 gcaggccagg gccgtcagca ccaggggatc ggaatccccc cagtccgctg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagtc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agcttcatca cattccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggataa gaggggaaga
     9661 acatccatca gggcatggta acggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcact
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggct
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatca aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggtct gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg taggatacga ccccgcccag ttcaccacct tcatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggatttt ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaagctt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgctgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg tggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgctggtgnn
    11341 nnnnnnnnaa gccaagggca tcgtcacccg caatctggtt accggcgaaa tcaaatccta
    11401 cgcaggggat accgtcctgc tctgcacggg cggctacggc aacgtgttct tcctgtccac
    11461 caacgcgatg ggctgcaacg tcactgccgc ctacaaggcc tacaagcgcg gtgctttctt
    11521 cgccaacccc tgcttcacgc aaatccaccc cacctgcatt ccggtcaagg gcgactacca
    11581 gtccaaactg acgctgatgt cggaatccct ccgcaacagc ggccgcatct gggtgcccaa
    11641 gtcccgtgaa accgcagaaa aaatccgtaa aaaggaaatc aagccttccg atgttcccga
    11701 agaagaacgg gactactacc tggaacgcaa gtatccctcc ttcggcaacc tggccccgcg
    11761 cgacatttcc tcccgcgccg ccaaggaagc ctgcgacgac ggccgcggcg tggccgtcac
    11821 cggcaagggc gtcttcctgg attttgcgga tgaaatcaag cgcatgggtc gcgaatggat
    11881 tgacggccaa tacggcaatc tgtttgacat gtacgaagaa atcacggacg acgaccccca
    11941 tgaaacgccc atgatgatct accccgcctc ccactacacc atgggcggcc tgtgggtgga
    12001 ctacaacctc atgtccaatg tgaaggggct gcacgtcctc ggtgaagcca acttctccga
    12061 ccacggcgcc aaccgcctgg gagcctccgc cctgaggcag ggcctgtctg acggctactt
    12121 cgtcattccc gccacgctgc ccgcttacct gacgaccacc aaacccggcg ccgtcaccac
    12181 cgccgccccg gaattcaagg ctgcggaaga cgaagtgaag gaacgcatca acaagctcct
    12241 gaatgtgaag ggcaccaaga cggtggactc cttccaccgg gaactgggcc tcattatgtg
    12301 ggaagactgc ggcatggccc gcacggaaga aagcctgacc cacgccattg aacgcattcc
    12361 ccagctccgc aaggaattct gggaaaacgt gcgcgtaacc ggcacggcgg acggcatcaa
    12421 cgcggaactg gaaaaagcct gccgcgtggc cgacttcctg gaattcgccc agctgctctg
    12481 ctatgacgcc ctgaaccgcc aggaatcctg cggcgcccac ttccgcgtgg aataccagct
    12541 gccggacggc gaagctaagc gcaacgacga tgaatacgcc tatgtagccg cctgggaata
    12601 cactggcgtg gacagcctgc ctgttctcca caaggaaccg ctgaccttcg agaacgtgca
    12661 ccttgccatc cgcagctaca agtaaagata gccaatacat taacactcaa aagaaagatt
    12721 ataacatggc taaaacactc aatctcactc tcaaggtctg gcgccaggaa aaccgggaag
    12781 ccaagggccg cattgagacc tatgccgcca aggacattcc ggtggacgcc tccttcctgg
    12841 aaatgctgga catcgtcaat gaaggcctgg tcaaggaagg caaggaaccc atccattttg
    12901 accacgacag atcggaagag cacacgtctg aactcca
//
