LOCUS       gnlProkkaMDOLKGLI_20   10703 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDOLKGLI_20.
ACCESSION   gnlProkkaMDOLKGLI_20
VERSION     gnlProkkaMDOLKGLI_20
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 04:13:56
            Original ID  :: gnl|Prokka|MDOLKGLI_20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10703
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10703
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1389:5703]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1390..5703
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10703
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10703
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             2..163
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIA
                     SIANLIKK"
     CDS             178..1326
                     /locus_tag="ctg20_2"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1390..2109
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-16, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2130..3431
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3448..4572
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.8e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4582..5703
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg20_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.2e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4672..5679
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg20_6_Aminotran_5.1"
                     /locus_tag="ctg20_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5700..5843
                     /locus_tag="ctg20_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6046..7530
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.3e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7484..8743
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             8752..9498
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKKF"
     CDS             9502..10542
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 ggttaagggt agtggtaaga aacagattga gccgggatgt gagattattg tgcctggtaa
       61 ggctaagaag aaagggaaca tagctaatat tttaggttat gctacttcct tcagttcttt
      121 gggaatgatg attgcttcta ttgctaatct tataaagaaa taatagaatt tacttttatg
      181 tcagaacaac gacaggataa aaacttgctc tctgaaccac acaagacaga aagtgatgag
      241 atagaaattg atttggtcga tatctttcgc aagattattg ctattcgtaa aaaattatac
      301 aaagccgttg gaattggttt tattattgga ataattgtag cggtaagtat ccctaaacag
      361 tatacagtaa aggttaccct ttctcctgaa atgggtaatg cgaaggggag taatggttta
      421 gccggacttg ctgcctcgtt tttaggagat ggggctctaa taggggaaag cacagatgcc
      481 ttgaacgctt ctctttcagc agatattgtt tcttcaactc cttttttatt ggaactttta
      541 gaaatggaag tctccgtttc taaaaaggat gataaaatga ctttggggtc ttatctcgat
      601 gaagagtcat ctccttggtg ggattatctt ataggttttc cgggcatagt aataggagga
      661 gttaaatcat tattcggaga agatacggtt cctgccagtg gagggcggca aggaactatc
      721 gaattgacga aagaagtaaa tgagaagatt aattttctta aaaagaagat tagtgcatcc
      781 attgataaga aaaccgccat aacgagcatt acggtcacct tacaaaatcc gcagatcact
      841 gcggttatag cagattctgt cgttcataaa ttacaggaat atattattgg gtatcgaact
      901 tcaaaagtaa aagaagactg tgcgtatttg gaacggttgt ttaaagaacg tcagcaggaa
      961 tattatgctg ctcaaagaaa atatgcggat tatgtagacg cccatgataa tgtggttctt
     1021 caaagtgtac gtgctgagca ggagcgttta cagaacgaca tgagtttggc ttatcagata
     1081 tatagtcagg ttgctaatca gttgcaggta tccagagcca aagtacagga ggaaaagcca
     1141 gtctttgcag tagttgagcc tgccgttgta cctttgaaac cttcaggtat gggactcaaa
     1201 atttatattt tattatttgt gttcctgtcc gtatctggta ctctcgtgtg ggtgtttttt
     1261 ggcaaaagtc tgctggctag cttgagaaaa gaactgaaaa ataaggagat agaacaggat
     1321 aaatgatgct aaaacgtcgt ttacaacatt cttacatcaa ttaaattcac ttactatatt
     1381 attaaacgaa tgatacgtac agctatgata atggctgcgg gcatgggaac ccgttttggc
     1441 caatatacag aattgatacc taaagggttc gtcaaagtgg gaggtattcc aatgatagtt
     1501 cgttctattg atactttgtt atcatgtggc attgagcgaa ttgtaatcgg tacaggatat
     1561 aaacaagaag tttatgaaga attgaagaca gactatccta tgcttgaaac ctgttttagt
     1621 cctcgttatg ctgaaacaaa tagtatgtat actttatata atacgcggga gattctgggc
     1681 aatgatgatt ttttattgtt agagtcagat ttgatttttg agaaacaagc aataatgagc
     1741 ttattggagt gtcctgcggc agatgcaatg ctaatagctc cagtgacaaa gtttcaagat
     1801 cagtattatg tggaacatga tgataatttt cgcctttctt catgttctgt caataagaat
     1861 aaactaaacg ctaaaggcga attggtcggc atccataaac tatccggttc cttttacaaa
     1921 ataatgtgtg ctgattatgc gagtattgtt gatgaacaac ccaatttggg atatgagtat
     1981 gaattactac gaatatcttg ttctcaatct cctgtttatg tgcataaagt agaagggctg
     2041 aaatggtatg aaatcgatga catatcagat ttggaatatg cagagaaata tattgttccg
     2101 tattgttaat taaaataata tatcaaatta tgagtaagac agtttatatt gggatgactg
     2161 cggatattat gcatccagga cttatccgca ttattaatga ggctactaaa tacggtgatg
     2221 ttataattgg tcttcttaca gataaagcta ttgcggagca taaacgcctt ccttatctga
     2281 cctatgaaca acgaaaagag gtagttcaga atattaaagg cgtatgtaaa gttgttcctc
     2341 aagaagaatg gagctatgtt gagaatctca aacgcattaa acctgactat ataattcatg
     2401 gtgacgactg gaaaaccggg cctttacgtg aagaacgtgt gcgcgtattt gaagtgatga
     2461 atgaacaggg aggaaaggtt atcgaaattc catatacttt gggaattaat tcatcttctt
     2521 tggataaaga tattaaggct ataggtacaa cccctgatgt acgtttaaaa tcacttcgtc
     2581 gtttgataaa tgccaaaccc gtagttcgta ttttggaagc tcatgatgga ctatgtggct
     2641 tgataattga aaatcaggaa atattaaaag gggataagag ggaagtattt gacggaatgt
     2701 ggtctagtag ccttacggat tcaaccagta aaggtaaacc tgatattgag gcggttgatt
     2761 taactacccg attgcaagat ttgaataata ttctggagtg tactactaaa cctattattt
     2821 ttgatggaga tacaggtggt aaaattgaac atttcgtatt tacagtacgc actttagaac
     2881 gtcatggaat ttcagctata ataattgaag ataaagttgg attaaaaaag aattcattgt
     2941 ttggtacaga tgttattcaa actcaagata caatcgaagg tttctgtaat aagatcaaag
     3001 caggaaaggc atctcagatt actgatgatt ttatgattat cgctcgtatt gagagcctta
     3061 tagcgggaaa gccggtaagt gatgctttag agagagcttt tgcatatgtc caagcgggag
     3121 cggacggtat tatgatacat agcaaaaata agtcgggtga agatataaaa gaattttgtt
     3181 tggcgtttcg aaaacagtat gctcatgtac ctatcgtggt tgtgcctact acatatgatc
     3241 atatttatga gtctgaattg tgtgattggg gtgtgaatat aattatttat gctaatcata
     3301 tgcttcgtgc cgcttatcct gctatgatga atgtcgcaaa gataatatta gagaatgaac
     3361 gtgctttaga ggtgcgcgaa ctgtgtatgc ccataaaaga aatattggaa ctgattccag
     3421 gtactaaata aaaagaggaa tatcattatg ttaagcgtag aaaaagttta tgaaacgttt
     3481 ctgagtcatg acgttgattt ttttacagga gttccagact cattactaaa aaatatttgt
     3541 gcctatatca cagaccatac ttcacgtgag aaacatatca tagctgctaa tgaaggtgcg
     3601 gctgtaggaa ttgcttcagg ttattatatg gcatcaggta aggttcctgt ggtttatatg
     3661 caaaattccg gcttgggtaa tactgttaat cctctgctgt ctcttgcaga tgaacaagta
     3721 tacagttttc caatgctttt gatgattggc tggcgtggtg aaccgggaac aaaagatgaa
     3781 cctcagcata aaaaacaggg tgaggtaact ttagatttgt tgaaagcaat gcggattcct
     3841 tatataattc ttgattcaaa tgagaatgat gcatttattc agctccatga tatcatacaa
     3901 tcagcaaaaa ctaagaatat tcctcatgca ataattattc ggaaagatgt ttttggcaaa
     3961 tataaacttc aaaaagagtt cggatgtaat tatcctttat ctcgtgagga tgctttgcaa
     4021 atagttgtgg attatctgcc tgaaaattca gtggtcgttt ctactactgg caagctttct
     4081 cgtgagttat ttgaatatcg agaaatgaaa gagcaaggtc atgaacatga ttttctcacg
     4141 gtaggctcta tgggacatag ttcatcaatc tctttgggta ttgctatagc aaagcaagat
     4201 agacctgttt attgcttgga tggtgatgga gcatttatta tgcatttagg ggcaattagt
     4261 aacattggcg atttatctcc taaaaactat tatcatattt tgtttaacaa tggtgctcac
     4321 gagtctgtag gaggacagcc tactttagga tttagtttag atattccggc tattgtccgg
     4381 gggagcggat ataagcatac ttatactgtt tgtacaaaag ttgaaattga agaagcaatg
     4441 aagcagcttc caaagttatg tggtcctgtt ttgttggaaa taaaggttaa aatagattct
     4501 cgggagaatt tgggacgtcc cacgactact cctatagaga ataaggagca ttttatggat
     4561 tttttaaaat aaatatattc gatgaaaata gaaagaaaaa tattattaaa tcctgggcct
     4621 gccactacta ctgacagtgt aaaaatggca caagttgttc cggatatttg tcctcgcgag
     4681 aaagaattcg caggtatgat gaaacaactt cgggacgatt tggtcagagt tgctcatggg
     4741 aatttggaaa aacataccgc tgtattattt tgtggctcag gaaccatcaa tattgatata
     4801 tgtctaaatt ctcttcttcc tgaagacaaa agggtgctta tagtgaataa tggggcatat
     4861 agtacccgtg ctgtagaagt gtgtcaatat tatggtttgc ctcatattaa tttggaattt
     4921 tccgtttacg aacgtcctga tttatcggtg gtggaaaatg tgttgcaaga aaatcctgat
     4981 atagctatgg tttatactac tcatcacgag acgggtacag gaattctgaa ccctattcgc
     5041 gagatgggcg ctatagctca taaatatcag gctaaatttg tcgtcgatac tacttcttct
     5101 ttgggcatga ttccttttga tatagagaaa gataatgtgg atttttgtat ggcatctgct
     5161 caaaaaggac ttcaagcgat gacaggtctt tcttttatta taggcaatga ggaacagatt
     5221 aagttttcaa aaaaatatcc caagcgttct tactattgta atctttattt gcagtatgag
     5281 aattttgaga gaacaggtga aatgcatttt actccaccgg tacaaactat ttacgccact
     5341 cgtcaggcat taaatgaata ttttgaagtg ggtgaagaag ctaagtttgc ccgtcacaaa
     5401 agagtttttg aggctattca ttcaggtata aatgaaattg gtcttaaaag tgtaataaag
     5461 cgtgaatggc agtcaggact ggttgtctca gttcaatacc cagaagatcc caactgggat
     5521 tttgagaaaa tacatgatta ttgttatgag cgtggattta cgatttatcc aggtaagata
     5581 tcaactgagg atacttttag aatctgtgct ttaggagaga tagaagtaga tgatattgag
     5641 aacttcttta aagtactaaa agctgcatta aatcattata acgtcacatt accgatgtca
     5701 tgattgcaga aatattattg aagattcgtc atttttattt ttcccttcgt ggtatacact
     5761 tccatccgga aagtgttatt tctggagtgc ctattcgtag ctttcgctta gtaggcaaat
     5821 atggcaatat taatttgagg tgatgcatta ggagttcttt attcttataa aaaggcatcg
     5881 gtagttatag gagataatgt ttgtgtaggg taatttgctt ttagtgggag agaccatatt
     5941 agaattgcgg taaggggcga agaagataat aaccaattag tgagaatatt ggaaaaatat
     6001 aattgatatc ggtaaatgta gttgttttta tactgtattt aagtaatgga aaatctaaag
     6061 cagaaaactg tatcaggaat aatgtggagc gctatagaac gtttctcttt acaaggagta
     6121 cagtttataa ttcaaataat attagctcgt ttgttactac catcggatta tggtatgatc
     6181 gggatgttag ctatttttct tcaagtcgct caagtattta tagatagcgg ttttacaaat
     6241 gctttaatcc agaaaaaaga tagaactgaa gaggattttg ccactgtctt ttattttaat
     6301 attcttgtcg cagtattatt ctatggtata ttgttttttt cggcttcttt gattgcagac
     6361 ttttataata tgccgacttt agttcttgta attcgtttta tagcattgtc gttgataata
     6421 aatgctttat cggctattca cagaacgaaa ttaattattt ctgtaaactt taaaactcaa
     6481 tctaaaattt cattaggtgc agcttttata tcaggcgtga ttggaatatg gatggcttat
     6541 gtcggttgcg gggtttgggc tttagtttgg caaactctct taaatagtat aattttgaca
     6601 attttgtttt actgtttagt tcattggaaa cctttacata ctttctccaa aagttctttt
     6661 gaaagattat tcaatttcgg atctaaatta ttgatctcaa gtcttatcaa tacagtatat
     6721 cgtaatctgt ataccattgt aataggaaaa aagttttctg ttgtagagct tggttactat
     6781 acaagagcag aacaatttgc tatttttcct tccaataatt taaatgcttt agtttctaga
     6841 gtagcgtatc ctattttaag ttccattcaa gatgatgata aatgtttaac aaacgcatat
     6901 cgaaattata tcagattatc ctcatatata atttttcctt taatggtagg tttacttgtt
     6961 ttggctaatc ctattattag tctattgtta acagataaat ggtctggggt tgttattctt
     7021 ttacagatat tatgtttgga ttggatgttt gatcatttga gccaaattaa tttgaattta
     7081 ttatgggtta aaggaagatc tgatctgtcg ttacgtcttg aaataataaa aaagacgatt
     7141 gctatattca ttctttttgt gtcaattcca tttgggcttg aggtgatgtg ttggggtaga
     7201 gttatttact ctctgatagc gacatatttg aatacatatt atactaattc tcttattgat
     7261 ttgaccttaa agttgcaagt taaagatgta tttccaagtt taatactctc tttcataatg
     7321 ggggggatcg tttttatatg tatttctttc tttgaaactg atatagtaaa aattgtgatt
     7381 ggatgtatta ctgggatgtc cttctatatt ttactttctt ttctttttaa gctagattct
     7441 tttttttgta ttttaacatt gatcattaaa actaaaaaca tagatgaaaa tattaaaaaa
     7501 gatttttcaa gtaatagtaa agataattaa ccattgtgtg ccagttgata gtagatcatt
     7561 gtattttatt cctcatccta attgtagaac agataaatat gatattataa attattcgtc
     7621 agataatgtt ctcgttctgt taaattattt gctaaaaaaa gatagtgctg aatattataa
     7681 aatatatgtt gaaatttatg attcttctcg tatttcagaa tatcaagaat atatttatgg
     7741 cataaatcct aatattaggt gtactttttt atgtgcatgt gttggacgtt ttttctttaa
     7801 taaagtatct tttaaggata tgttgtatgc ctttttttgt ttttgtagag caagtaaatg
     7861 ttttacagct actttttatt atgatttttc atttaaaaaa cgctctcaac agattatttg
     7921 tttggggtat tatactccat tcaaagatga ttatcatatg ggagatcatt cttatgataa
     7981 atttcgtaat acaacatgta actcatttga ttactctatt gctacttctt gtttaagtgc
     8041 tagaataatt tcaatagatt gtggaatctc atatgataaa ttcaaagtct taggatttcc
     8101 cagaaatgat ttgttgatat cgaaaaataa ttgcaatgtt attaaaagag aaatttcgaa
     8161 atttgcggga tatgatgtaa ctaaatatat agtttatact ccaacttttc gtgattatga
     8221 gactgttact gaaggtaatt tgcgttcaat actcggatat gttgattgtg atttgttgaa
     8281 gttatcgaaa atactattga agtttaatgc ggctttaatt cttaaattac atcctttgca
     8341 gaataaaaca gtcttaaaaa aagatttacc caaaggtata cttgtttttg aacaaacata
     8401 taaatatgga ttgtatgatc ttttgtcatt ttcagatgga atgattactg attatacttc
     8461 tacctatttt gattttttat tggtaaataa gccagtcata tttaatttct acgatattga
     8521 agaatatcgt agagtaagag gtttctcatt tgagccaata gaattttttt gtgcaggtga
     8581 tattgtttac aattataatg aattgataga tgctgtgatg ggacttctgg ctgggaaaga
     8641 tattcatgct gaacatcgac gtcatatttc tttattgatg aatcaatttc aagatgataa
     8701 ttcaacaaag agaatatgtg acatattttt aaatgaaata taataaataa aatgaattat
     8761 gcatttgtgg tgcaggcacg tttaggttct acacgtttgc ctggaaaaat attgaaacct
     8821 ttctatggta atcaatcgat tcttgactta atggttcata agctttctgc tatatcgaat
     8881 attccagtaa ttattgctac aacaaattct gttatcaatg aacctattga aaagaaggca
     8941 cttgcattag gggtaaagtg cttcagaggt gaggagaatg atgttttaaa acgattcatt
     9001 gatgttgctg aatattttga tatacagggt atattccgaa tatgttctga taatccattt
     9061 ttagatgtac atgcggcaag gcaattggtc gaaatagcaa tgaaatcttg taacgattat
     9121 ataagttttg atattgatgg tactccatca attaaaactc atttcggttt ttggggagaa
     9181 tttgtaacgc ttgatgcgct gaagcgagtt ataggattta ctgatgattt attgtatcgt
     9241 gaacatgtta ctaattatat atatagtcat cctgaacttt ttaatattca atggatttca
     9301 ggatctccag tcgtgtcaaa acatcataat attcgactca cgattgatac gttagaagat
     9361 ttttctgtag cacagagaat atatagggat ttacaagaaa aaagagtgga aatatcgata
     9421 gaagtgattg tagactatgt tcgaagacat gcagaataca ttcaactgat gaaacaacaa
     9481 ataaaaaaaa aattctaaat aatgaagaat acttatatta ttggtgaaat agggcagaat
     9541 cataatggtt ctgttgactt ggctaagttg attattgaat taatctcacg acctgtacat
     9601 gaggatgttt ttggtatgga tttcatgcca atgaatgctg ttaaaatgac taaaagagat
     9661 ttatcagaag aattggctgt ttctcaaatg aatcaaatat atgacaatcc taattctttt
     9721 gggcgtactt atggtgaaca tcgtgctttt cttgagcttg atgatcaagc gcattttgag
     9781 atttataaat atgctaagtc attaggatta gattttatcg agacgttatg tgccaaagga
     9841 tgtctgtctt tgcttaaact gttcacaccg gataggctaa aagttgctag tcgtgatttg
     9901 actaacttac cattgcttga agcattagca gaaactcata ttcctattat attatcgaca
     9961 ggaatggctg gtcaaagaga acttgacaat gcattagatg tgataacgag atatcatagt
    10021 aatatagcta ttctacattg tgtatctcag tatccaactc atccaaataa tttgaatcta
    10081 cgtacaataa catatttgaa gaagcattac aataagtttg agataggttt ttctgatcat
    10141 acaataggta tttctgctgc tacagctgct gtagcgatgg gagcggaaat tatagaaaag
    10201 catgtaacaa ttgatcggca tatgaaagga acagaccagc ttggctcttt aggtccagat
    10261 ggggttaatc gtatgattcg agatattcgc atagcagagt gttggcttgg tactgaagat
    10321 ctttatatag aaaaaggggt ggagaagtct aagataaaac ttgaacgttc tattgccact
    10381 cgaaaatata ttccagcagg tagtattatt caagagtcgg acattcattt actgagtcct
    10441 ggtgatggtt ataaatggat agataaaaaa aatgtaattg gtcattttgc taaacaagat
    10501 atatcagcga atgaaataat atatcctgat tttattgaat agatatattc ctactgcaac
    10561 ttgtattacg gtatagagta ctgcctgcta taagctaagt agtgattaat aaataagggt
    10621 aaaatactaa aaaaatgaaa gagataaagc ttatacttac agatattgat ggcgtttgga
    10681 ctgatggcgg aatgttttat gat
//
