LOCUS       c00492_gnlPro..         2779 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HAODCOOH_492.
ACCESSION   c00492_gnlPro..
VERSION     c00492_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 12:37:54
            Original ID  :: gnl|Prokka|HAODCOOH_492
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2779
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2779
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2779]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..2779
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..2779
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..2779
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..1013)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg492_1"
                     /sec_met_domain="IlvN (E-value: 1.2e-47, bitscore: 149.7,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.5e-38, bitscore: 120.5,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQRQGKTYDKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGNAMDRTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYHSVKTGNEAQISIDSNSKPDYREKLEEELKALRESEMWQTAV"
     CDS             complement(1077..1820)
                     /locus_tag="ctg492_2"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGNELSFFCDEV
                     SENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             complement(1820..2383)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg492_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.2e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             complement(2402..2779)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg492_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.3e-30, bitscore:
                     91.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCVFMGDGGLQMNIQELGTIMEQKAPVKIICLNNNYLGNVRQWQA
                     MFFNRRYSFTPMLNPDYMKIASAYDIPSKRVFSREELKAAIDEMLSTDGAFLLEACVVE
                     EGNVLPMTPPGGSVNQMLLEC"
ORIGIN
        1 gtcacggcag tctgccacat ttcgctttcg cgcaatgctt tcagttcttc ttccagtttc
       61 tcacgataat ccggtttgga gttagagtcg attgaaatct gtgcttcgtt accagtcttc
      121 acactgtgat acaacttttc aacgaccggt ttgatagcat cgtggaaggg gcccatccag
      181 tcgagagcac cacgttgagc tgtagtagag cagttagcat acatccagtc cataccgttc
      241 tttgcaaaca acggcatcaa tgactgagtc agctcttcta cagtttcgtt gaatgcttcg
      301 gaaggagtgt gaccgttttc acgtaacact tcgtattgtg ccagcaacag accctggata
      361 gctcccatca atgaaccacg ttcgcctgtc aggtcggaag tagcttcgcg gatgaaagtt
      421 gtttcgaaca aataacctga accgataccg atacccaatg cgattgttct gtccatagcg
      481 ttgcctgttg catcctgata gatagcgtat gaagagttca acccgcgacc ttcaaggaac
      541 atagtacgca aggatgtacc cgaaccttta ggagcaacca tgattacgtc gatatctgca
      601 ggaggaacta cacctgtgcg gtcactccat gtaatagcaa aaccatgaga gaaataaaga
      661 gcttttcctg cagtcaggta aggcttgata gtaggccata cagacattac tgctgcatca
      721 gacaacaggc acataatgat cgtacctttt tcgcaagctt cttcaatacc gaacaaagtt
      781 tcacccggaa cccatccgtc agcaaccgct ttgtcatatg tctttccctg gcgttgacca
      841 acgattacat tgaaaccgtt atcacgaagg ttcagagcct gtccgggacc ttgtacgcca
      901 taaccgatta cagcgattgt ttcatttttc aatacttcac gagctttttc caatggaaat
      961 tcatcacgga taactacatt ttctacagtt ccgccaaaat tcaactgtgc catttttttt
     1021 gtttttttgt tttgatgact tgcgccatct gttattaatt gattttatac tctatattat
     1081 tcaaatatca ctttggaacg gcatactacc tcgctgccgt ttttcttcac ctctacatga
     1141 aactcgtttt cactcacctc atcacagaag aaagagagtt catttccgaa ataactttca
     1201 gccacatacg ccatttcaaa ccggcggata cgtttcgtct gatacagttc tatcggaaac
     1261 aagtcaagta tgtgctcgat ataacgaata ctgtttacgt gtccgttaat atcgatatca
     1321 ctgtattttg ccgtcagcgt cgcaacaggc tgattgcttg tcaccttgat acgcgaaggc
     1381 ttttctatcg ggcagggttc atcgcatata taatcgacga tgcttcctcc atgcaatgcc
     1441 aacagatcgg caggcttacg agtattcaga ttgatcatcg cccatacgga acgggcatag
     1501 ccgatcttct ttccatcctt gtcaatgacg gcaaagttac ggtcggtaaa gagacgatag
     1561 acattctcca cccatgtctg aaccgagaac ttctcgtatt ggtaaggcat ctcgtccagc
     1621 tcgatcgcca gacgggaaag cacccatgtg taattgtcct cgttcagcgt agcaatacca
     1681 aatccacggt cgctggcatg aaaacctgcg caattcagca gatgattccc cagcacgccc
     1741 atggtcaggc ggccgttaaa atctacgtga aacggctctg ccacaaactg ataagtccct
     1801 attttatttt cttcactcat tactcctgtt cctttttact ttgcttatac ttcgcttcct
     1861 gtccgtccag gaactcattc acacgttcga aacagctggt agtaatagcc acacggcccg
     1921 aacggacaaa ttgcagcaca catttcaaag cccgaagttc ttcgtaaagg gaagtaatct
     1981 cttcactcat gccgttcttc tcgacgatag agaataccgg attcacctct acaatgcggg
     2041 cattatatct gcggatcact ttagatgctt ccggagtctc ctgaaaagca ggagtagata
     2101 ccttatataa ggctatctca tggaaataaa tctcgtcttc cgtaaaatag tgcgcctgaa
     2161 tcacatcaat cttcttttcg atctgcttca ccaccttttc gatagtgtcc ttatcagtcc
     2221 acgctgtaat cgtatattta tgtactcctt taatggaaga agcagaaacg ttcaaactct
     2281 cgatgtttat ttgccgacgg gtaaatacag cggtcacctg attcagcaat ccggctatat
     2341 tttcagaatg aactataatc gtatataatg tcttatcact cataactttc taaattaagg
     2401 attaacattc cagcaacatc tgattgactg aaccgcccgg aggggtcatc gggaggacat
     2461 tgccttcttc taccacacag gcttcgagca ggaacgcccc gtctgtcgag agcatttcgt
     2521 cgatggccgc tttcaattct tcccgtgaaa agacacgttt ggaaggaata tcgtaggcgg
     2581 aagcgatttt catgtaatcc ggattcagca tcggagtaaa tgaataacgg cgattaaaga
     2641 acatagcctg ccattggcgc acgttgccga gataattgtt gttcaggcag ataatcttca
     2701 ccggagcttt ctgttccatg atcgtaccca gttcctgaat gttcatttgc agtccgccgt
     2761 cacccataaa tacacatac
//
