LOCUS       c00012_gnlPro..        14417 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MGOOKDGP_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 14:43:47
            Original ID  :: gnl|Prokka|MGOOKDGP_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 43492
            Orig. end    :: 57909
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14417
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[53492:56982]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14417
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14417
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(472..1062)
                     /locus_tag="ctg12_43"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPILVQRIFQSDQQNEAKAAAE"
     CDS             1302..2912
                     /locus_tag="ctg12_44"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             2976..3596
                     /locus_tag="ctg12_45"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPSAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAASKDILENSDEFSDLVEPDENGAPPMH
                     SGKMKRPDSSPPPRFSPLFFIPGTPFPRMGSCAAKSISSLPEP"
     CDS             3593..4366
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_46"
                     /sec_met_domain="adh_short_C2 (E-value: 2.4e-75, bitscore:
                     244.9, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             4390..5595
                     /locus_tag="ctg12_47"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMIAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSAGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPTKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             5729..5977
                     /locus_tag="ctg12_48"
                     /transl_table=11
                     /translation="MRVSPSFIPEQDAVAIHGSRIVGNIVDATSVIRADDGKEYEVLGM
                     GPIAVLPEYQRRGIGRRIIGMRRPSRSVRCKGDPYPA"
     CDS             complement(6272..7012)
                     /locus_tag="ctg12_49"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7187..7276
                     /locus_tag="ctg12_50"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             7346..8014
                     /locus_tag="ctg12_51"
                     /transl_table=11
                     /translation="MSLSATAATALLDSSIVGYSDFASQTADFGTRKDSVSITSDDSNL
                     TLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSVSWGVGLNTDRKLQ
                     GLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYSNSGLKFGNQQINQ
                     ILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGLLGLAALMMRRRRA
                     "
     CDS             8269..8676
                     /locus_tag="ctg12_52"
                     /transl_table=11
                     /translation="MQSPASLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSLKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg12_53"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg12_54"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_55"
                     /sec_met_domain="SucD_FumR (E-value: 2.4e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_56"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.9e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12723..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_57"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.9e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             14123..14416
                     /locus_tag="ctg12_58"
                     /transl_table=11
                     /translation="MEAAPEPDPLPFEAIRIHGERTVGPPSTSADGHSAHGTFTIPEGK
                     GGKKLYGTCSLFLGVDDWGSLEVKDSGGNVVAQVDLKENPQTAGEQGGHKYHT"
ORIGIN
        1 cttttctgta atgccgtgac atggaacaag aaaatctctt gatttctact tgccaccatt
       61 tacattggtg ccagcaaacc tccgtggatg cggaggttcc agtagttaac aaacactgta
      121 tttaattcga attatgaaga acatcgctat cctcgccatc gccggcgccg cttgcctggt
      181 cgcttcctgc tcccagcagc agcagcaaca gcaaaccacc gctcctgctc ccgctccggt
      241 tgtgcaggcc aagggcaagt aagtttgcag cggggttttg ccctgcaaca ctagcaaatt
      301 atccaattaa tccgcactcg gtgtacgcac tgagtgcgtt tttatttgcc ctgagtccgg
      361 attccctccg ccatttgccg attcgccggg attttcctta aaaacggcgg ataccgcaaa
      421 ccgccgcggc gcagcaccgt gtgccggttc ctgccggatc aggcttcccc tttattcagc
      481 ggccgccttc gcctcattct gctgatcgga ctggaatatc cgctgaacca gaatggggcg
      541 tttcctggcc cacccgggcc agaccaggtg atgttccatg ccgtaggaat ggccctccgg
      601 aaaggccttg gaaacaaatg gttcccgcca gtcctcctcc catttgccgc cttcccggtc
      661 cttctgggtc agcgtcacca gatgcccgca gttcttccag gcatccagaa caatggagcc
      721 ctgcaatccc ttccccgcgg cattgacata cacgcaactg tgctccctgc ccgttccacg
      781 gtctcgaatc gtcagcccta tgcggaaata cttcacgggg cggcggcgca ggtcccggta
      841 caaatcctgc tggacctgcc agcacagccc cctgtcgcgc aggttggaat tgaccagaat
      901 attgttcagc cagccaaaca gcacagtcct gttgtcccgg gcaatcgctg cggactggac
      961 cacggccgtg tccgccagcc acctggcctc cgctccggca gcgggaagag aggcctgatc
     1021 cggcggcagc agcgccagga aggcattagc cagcccggac atttgctgct gcacgtaagt
     1081 ttgttgtata taatcctccg ccggaggagt acagcaggaa ctccatccgc acaaaagggc
     1141 ggcagcaagc aaaagcctga atgtctgcgt ggtcggcatg gcgcgccaag gctagcagac
     1201 tacgcgtaaa aatccagtaa agctttcaaa aatgccagcc tccgccctga cggctcttgc
     1261 cttccccttt ccatcccggt agaatacatc ctctcttcac catgctgacg atcaaaaatc
     1321 tcacaaaatc ccacgccgga cggaccttgt tcagggaaac ggaaatgacc attaactggg
     1381 gggaacgggt ggctctggtt ggccccaacg gagcaggcaa atccaccctg ttccgcatga
     1441 ttctgggaga agacacgccg gacgaaggct ccatcagcat ggatgaatac gccatcgtgg
     1501 gctatcttcc ccaggaagcc agcgaaccga aggatgaaac cgttctggaa atcgccctgg
     1561 gcatcacgcc ggaaatggaa caggccatcc acaccatccg gacggcggaa aacgccaaca
     1621 aaacggatac gccggaatac gcggaagcca ttgacacttt caacgccgcc aacggttacc
     1681 agctggagcc caaagccaag aaaattctca aagggctggc ctttcgggaa agcgacttcc
     1741 atcgccccgc ccgggaaatg tccggcggct ggatcatgcg cgcgtacctg gccaagctcc
     1801 ttgtcctgga gccggacctc ctgatgctgg acgaacctac caaccacctg gacctcctgt
     1861 ccctgctgtg gctccagcga tacctgaaaa actaccccgg agccatcctg atgatttccc
     1921 acgaccggga tttcatggat gagctggtgg aaagcgtgta cgacatcgac aacgaagaac
     1981 tggtggaata ccgcggcaat tactcggact tcctccaaca aaaggacgtg cgcttcgagc
     2041 agcttcaggc ggcctaccgt aaccagcaga aggaaatagc gcacattcag gaatttattg
     2101 accgtttccg ctccatcaat tccaaagccg ggcaagtcca gagccgcatc aagcagctgg
     2161 aaaagatgaa aatcattcaa aaaccggtag cccgcaggaa agtatttaaa ttcaacttcc
     2221 cccagcctcc gcgcagcacc cagaaagtca ttgagctgga aaaagtctgc caatcctatg
     2281 gcgaccgcag ggtttatgaa aacctggacc tgctggtgga acgcggggag cgcactgttc
     2341 ttgtaggccc gaacggcgcg ggcaaatcca ctcttctcaa aatcctggcg ggcatcatcc
     2401 ccattgactc cggacaacgc actcccggta ccacgacgcg catcggctac ttctcccagg
     2461 cgcgaacgga aaacctgaat ccggaaaata ccgtgctgga ggaaatcatg aaatgcagcg
     2521 ctgaaatccg ggaggaagaa gcgcgttcca tcctgggttc cttcctgttc cggaggctgg
     2581 atgtggaaaa acgcgtcagc gttctttccg gcggggaaaa atcgcggctc agcctggtca
     2641 aattcctggt ggatccgccc aacctcctgc tgatggacga gccgaccacc cacctggacc
     2701 ttttgtccgt agaagccctg gtgcaggctc tgaagcatta tgaaggaaca ctggtcttca
     2761 tctcccacga tgtgcacttc atccgttccc tggcacaaaa aaccctgcat gtgaaccggg
     2821 ggaccatcac cgcctacgca ggcggatatg actactatct ggaaaagtca ggcattctgg
     2881 acgatgaaaa aggcggcatc acggcggaat aaggctcttt tttcagtttc ccctttttcc
     2941 ttgccgtgga tttcatcctg ccttaaaaga acaggatgaa ggcttttctt gttcctctct
     3001 tatattctgc gcttctgtcc ggagcctctc ttgcatttgg tgaaacggcc gccggaacgg
     3061 cttccccctc agcagcggct ccggcggaaa aaattccttc cgcggaatcc ctgatcaacc
     3121 aggccttttc ctttgccatc aatatccagc agacgttggc aggagttcag gacaaggaaa
     3181 gcgcggacaa cgccgtcaaa acgctgcagg acattcagaa ggacatccgg catttcctcc
     3241 agcttcagga taaattgaac gatgcggaaa aggagaaaga agacgccttg atagaaaaaa
     3301 tggaaaaacg aatggaaatg ctggacaacc gctgcaggca ggaaggcaaa cgcctgtttg
     3361 aggcccgcta ttacggttcc gccgcctcaa aggacatttt ggaaaattcg gatgaattca
     3421 gcgacctggt agaaccggat gaaaacggtg cgcccccgat gcactccggg aaaatgaaga
     3481 ggccggacag tagccccccg ccccgtttct cccccctctt tttcattccc ggcacgccct
     3541 ttccccgtat gggttcctgc gcggccaagt ccatttcaag cttgccggaa ccgtgaaaaa
     3601 cgggtttact gtgggcagca tgcaaaagtt agcaggtaaa acagccatcg ttaccggcgc
     3661 gggccgcgga atcggcaatg ccgtcgcgcg ccgcttcgct tcggaaggag ccagggtcat
     3721 cctgatcagc cgcagtccat ccagctgcgg gggggccgca gaagaaatca acaaggaatt
     3781 tccggattcc tgcaaggcct acccctgcga cgtagcggat tacgcggccg ttcaggaaac
     3841 catggccgcc attttgaaag acttcccgca gattgacatc ctggtgaaca acgccggcat
     3901 cacgcgggac tccctgatgc tccgcatgaa ggaggaagac tgggatgccg ttctggacac
     3961 caacctgaaa agcgcgttca atacagtcaa ggccctccag cgcgttctca tgaaatcccc
     4021 ggccgggcgc atcatcaaca tgagctccgt catcggtctc gtcggcaaca tcggccaggc
     4081 taattacgcc gcttccaagg cgggcctcat cggtttcacc aaatcactgg ctcaggaatt
     4141 cgctccgcgc aaagtcacgt gcaacgccat tgctcccggc ttcatctcca cggaaatgtc
     4201 caatgccatt cccgacaatc tcaaggaaga aatcgttaag aaaatacctt tgaaagaaca
     4261 aggttccgtg gaagatatcg ccgccctgac ggccttcctt gcctctgacg atgcccgtta
     4321 catcaccggg caggtcattg cctgcgacgg aggcatgacg atgtagggca ttccggtttt
     4381 caccattcca tgcgcggcat tttccttgtt tcctgctttc tgggaggaag cgccctgctg
     4441 gccgggtgcc gggaagaaaa taattccccc cgcccggcca cggaagatgc cgcgcgcatt
     4501 accagcgcac gccagtgggg agaaagccga tccgcgctgc aaaaacggga actggaccgc
     4561 gctgccggtc ctgcccttcc cattccggat gacctgccgt cccgggagct ggtcggcacg
     4621 acgcgccaaa tccatcagct cattgaagct tccggaaatc cggcacgttt tgaatcctac
     4681 acggaaacgg ttcccgcggc gggagcttcc ctgcgcatga tcgccatacc gggaggaacg
     4741 ttcctcatgg ggagtcccgc ggaagagccg caccggaaac cggacgaagg tccgcagcat
     4801 aaagtgagca tctctccctt ctggatctcg gaaacggaaa tcccctggga actttatacg
     4861 gccttcatgg aaaacgggcg tccgcgcgcc aaggacggcc agcttctgga ggaacagccg
     4921 gatgacgaac tgtgggactc cgtcacgcag cctaccgccc cctacgccgc catgaacctg
     4981 ggcatgggcc acggctatga acacggcctg cccgccatct ccatgtccca ccacgccgcc
     5041 agcaaattct gcgaatggct gagcgcccag accgggcatt actaccgcct gcccacggag
     5101 gcggaatggg aatacgcctg ccgggccggt tccgccggcg cctattctta cggaaacggg
     5161 gaagcctctc tggaccagta cgcctggtac tggaacaatt ccaatgaccg ctaccagaaa
     5221 acaggctcta aaaaaccaaa taagtgggga ctccgggaca tgcacggaaa tgtggcggaa
     5281 tgggttttgg actcttacgt tccggatgcc tacggcaaac ggagcggctt gcccacgaaa
     5341 gaccccctag tcatcatccc cggcgcccct cacatcgttc gcggcggttc gtgggaagac
     5401 gacccggaca gcctgagaag cgctgcgcgc cgcgccagca cccccgcctg gaaccgtcag
     5461 gatcctcaaa accctaaaag catctggtac ctgacggacg gaggcatgat cgggttccgc
     5521 gtggtgcgcc ccatgaacat tccggacatt atgacgatgc accgcctctg gaatttctcc
     5581 aagggggagc cgtaaagaac aatctttcat gaccattgca ttaagaacgg aacaatcctc
     5641 agaccatgcc gaaacggaac atgtcacgag agaagcgttc tgaaactatt tcgtccccgg
     5701 ctgcaatgaa cattacctgc tccatatcat gcgcgtcagt ccttccttca tcccggagca
     5761 ggatgcagtc gccatccacg gcagccgcat cgtcgggaac atcgttgatg caacgtccgt
     5821 catcagggca gacgatggaa aagaatatga agtgctgggc atggggccca ttgccgttct
     5881 tccggaatac cagcgccggg gaataggacg gcggataata ggtatgcggc ggccctccag
     5941 gtctgtgcgc tgcaaagggg atccctatcc ggcctgaaag gccgctatgt gaaagctact
     6001 gtgtaccata tggacgaaaa gcgcgctgcc gaatttgacg gcattttccg gtaaagaaaa
     6061 agctttccgg tactgcgtct caaaaacgtt tccagcaaat tgccgccatg cggaaaaaac
     6121 cggatacggc cccctgcccc cggaaattcc gtaccttccg gagggcatga atcccgcata
     6181 cggataagca attcttcctc tctggatata aaaaacaaga gctgttccgc aagaacagct
     6241 ctcatccgcc gatttttcgc catcaggaag ctcaagccct gcggcggcgc atcatcagcg
     6301 cggccagtcc cagcaggccc agggaaaccg tggctggttc cggcaccatt tcccctcgga
     6361 tttccgtgaa aatcggggat aataagctga aagtattggt tccgttggct cccgtaataa
     6421 cgacagaatc accaggcgct ccctcggcgt cataatggcc gcggatgccg ggagcagtca
     6481 atccgccgct gatcgttacg gtatctcctt ccgtgttagc agtaggggcg gctgttcccc
     6541 ccgcagcata taaatacgtt ttagacgtat cctgcatcaa gtccatcacg gactggctca
     6601 cggccaggaa acggtatgtc aatgccgcgt caagaagcag gggagaacca tccagggaag
     6661 aaaaactgaa cgtcagatta atccctgctg cagtagttcc cgtattggtg ctccagccga
     6721 tgaccgaatt gtcggagcca ttcagcacca ggaagccgta agtgacatta gcgcccaaat
     6781 tgttggcggc tccgcgcagc gtaaaactgt ccagtctgat ctctccggac agggaggagg
     6841 gagaagagga atcggaagga gccagggaag aagaccccag gccaagataa aacccatgga
     6901 tggtactatt gtaattatcc gtaccgggag tgtaataatt aaaaacggtc gctgcctccg
     6961 aggaaacagc aaagcttccc atcgcgatta aaaatgtcag tgttttcttc atatttatta
     7021 ttccttttgg atggcaactt gtagcgaatt tggaattccc caatcggatt tggaatccgt
     7081 caagtaatga aaaagaggcc aaatcaatca tgaaaccaat gaataacaaa gactgccccg
     7141 tcatcttagc aaaaggacca gagatattaa aaaatcatta ttttcaatga attataaata
     7201 caatatacta actcttaata tttttaattg cttgcggatt ccaaattcgt tattcaagca
     7261 caagtacata cattgaacct tgaatcattt tattaagata ctgaccatga ataaattatt
     7321 atccaccctg attctttcgg ccggcatgag cctaagcgct accgcggcta ccgctctgtt
     7381 ggatagctcc atcgtgggat attcggactt tgcctcccaa acggcggatt tcggcacccg
     7441 gaaagattcc gtttccatca cgtctgacga cagcaatctg acgttgtccg ggataacctt
     7501 caacggatac ggtgccaaca accgcgacgt tatgtctgtg acgatggttc ttgacctgtc
     7561 caaaatcaac actccggaga cctataccgc tctgtttaac gccaaaaaca gcagtgtaag
     7621 ctggggcgtg ggcctgaaca cggaccggaa actccaggga ttatggaaca acacctcata
     7681 cagcgggccc gtcgttgaca ccccgctggg cacggaaggt tccctgacca tttccgtagt
     7741 caccggagat cttggcaccc gcatctattt tggagacagc gctacgtact attccaacag
     7801 cggcctgaaa ttcggcaacc agcaaattaa tcagattctc atggacgcag gactggctga
     7861 atccatcgaa cagctctaca tccacgactc cctcctttcc caggaacaag ttggtcagct
     7921 gatgagtgaa atcgccagca ttccagaacc cgccacggct tccctgggcc tgctgggact
     7981 ggccgcgctg atgatgcgcc gccgcagggc ataagcctgt accgtccgcc tccctatatt
     8041 caaaggccgg ctcacaaaat cgtgagccgg ccttttcctt atccgttcaa acatctgccg
     8101 gaaaaaacag ggggaagaag cttctatttg ctggctaccc tcacggccag cacttgacgg
     8161 ggaaatggca ttcaggctcc cccgggaggg tcatttcaag agcttccggc cccgccccac
     8221 ttccgtacac gccccttttt cccatgccgg gacagccgga accggagcat gcaaagcccg
     8281 gcttccctca gcatccggaa cagcccatcc tttcagcaat ccatttcccc gcacggtccg
     8341 gatcgctgcg gttccgtccg tcggcaacag actccttccc tgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgccg
     8701 cgggcggaac taacgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgcagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agcttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcact
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggct
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatca aggcgacgct
    10321 ctcctcccgc tacatgatct ataccggcct gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct tcatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacattattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgctggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggc tgcaacgtca ctgccgccta caaggcctac aagcgcggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaagggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagtggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaaaaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggctgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgttgcccg cttacctgac gaccaccaag cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gccaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gacggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ccggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa agcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgct tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggctttggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 cagatttcct tgaaccagga ataaaatacc agacagttgc ttcctcatcg tcgcgcagcg
    13621 taaaaaattg ttacaccgga aggcacccag taatccagga gaccgtactt ggaaatgccg
    13681 gacgaaacct aagcaagccc ccgtccgaca gcgacggccc catctttctt cgagagagaa
    13741 aaacattgat tacaggaatt agactgatgc ccggaaggga tagcctcctg tcaagggctc
    13801 agcatgagag gaaaacattt tctaacaaac agacaacatt gatgtctatt aagggaatgc
    13861 actgagcgta agaattataa tattattttc tcatggaata aattctcatg ttcttaaaat
    13921 aacagaaatt tttcaaataa attcttattg acgctaaatc tgaataatgc tattgggaaa
    13981 atgcccgctg aggattgccc tcatcttgtt ttattcatta atctcagctt tttaatacct
    14041 gatgaatccg cctcatcgtt ctgccgttcc cgcttaccgg aaatggtact ttggagccgg
    14101 cggcagcccc ggcaggcggg gcatggaggc agctccggag cccgatccgc taccgtttga
    14161 agcgatccgg atccatgggg aaagaaccgt ggggccgccg agcacgtcgg cggacgggca
    14221 cagcgcgcac gggacattca ccatcccgga agggaagggg ggaaaaaagc tctacggcac
    14281 ctgctcgctc ttccttgggg tggacgactg gggaagcctg gaagtaaagg actccggcgg
    14341 caacgtggtg gcgcaggtgg atctgaagga aaacccgcag acggcgggcg aacagggcgg
    14401 gcacaaatac cacacgg
//
