LOCUS       gnlProkkaGBBPJOAN_4    21557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GBBPJOAN_4.
ACCESSION   gnlProkkaGBBPJOAN_4
VERSION     gnlProkkaGBBPJOAN_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 01:09:53
            Original ID  :: gnl|Prokka|GBBPJOAN_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 67818
            Orig. end    :: 89375
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21557
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11557]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11557
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21557
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21557
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             845..2176
                     /locus_tag="ctg4_56"
                     /transl_table=11
                     /translation="MEENQHTEFKESWHDEYTRYISAFCNTEGGVLYIGIDDKGEVVGI
                     EQPKKLIEKLPNFIAQKTGIMPLIHLREKAGKEYLEIEVQPSAMPISVHGRYYTRSGSV
                     TSELQGNQLNMFLAAKMGLTWESVIEEDFSLEDIDTDTVERFKLLAKDRVPSIEQETDL
                     LALMERLNLIVGGRFKRAAVVLFGKNVQRYVLQARIKIGKFLTDTEVLTTDIVEGNLIQ
                     QVDRALDILRTKYLLSYISYEGIHRREKLVYPYEALREALLNSIIHREYFVSSEIQVRV
                     YEDKLVIGNEARLHDITVEDLSRPHPSRPHNKLIADVFYKAGFIESWGRGTQRIIDNCL
                     AEGLSAPVYEHKMGFLYLTFFHERINERINERINERINELSDMEREVYQILREEPTIRQ
                     IDLANRLDLTEQYIRKLIKKLKEHGWIERIGARKNGYWKIIEKS"
     CDS             2173..3435
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 121.7;
                     E-value: 6.9e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_57"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.4e-25,
                     bitscore: 82.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILILNTSELTGGAAVAANRLAKALGKSGVEVSMLVRDRKTDHV
                     KVFSVNNSWTSHRLNSFRFIWERLIIFICNFFSKKNLFQVSIANTGTDLSKHPLVQQAD
                     VIHLHWVNQGFLSLSDIKKLVNTGKPIVWTMHDLWPATAICHYPGGCEKYISNCYQCPM
                     LKRNPFFDLAASVFKEKGKIGLSKITFVGCSRWIMEEAQKGNWLRTACFTSIPNPIDVT
                     AFKRMEKRVARKRFDLPEGKFLLLFAAAKLSDTRKGAIFLIEACEKLKEKYQDRIEIVL
                     MGNSSEELISQFPFKVNTLGYISDQDSMISVYACADMFVIPSLEDNLPNTIMESMACGT
                     PCVGFETGGIPEMIDHLKNGYVAKYKDTNDLAVGIKWIIDNQETFRFSEACVRKVHDCY
                     RESVIAEKYIALYQSLCNKRK"
     CDS             3534..5396
                     /locus_tag="ctg4_58"
                     /transl_table=11
                     /translation="MDDQHKPEWIKVDEWDFVEYVDSLLRSQEAVDLEFKTARAGFPNS
                     VWETYSSFANTDGGTIVLGIKEKNGALFVEGLLPEQIVSYRQIICNQLNNPDCVNVNLL
                     TDKNIQEVDYRGKSLLLIYVPRASRSQRPVYLTRNPLNGHTYKRNNEGDYKCTDTEVRR
                     MIADADEEHPRDSRILCNYSMEDIDLDSLKQYRLLLSSRQPDHPWLTLDDMAFLRKLGG
                     YRQDRQTGQEGFTLAGILMFGRTESITDNECAPSYFPDYQEKMSVDENVRWTDRICMDG
                     TWEANLFQFYRRVYPKLSSVLPKPFRLENGVRLEDTTTHVALREAFVNTLVHCDYMEEG
                     NITIEQWKDRYVFKNPGTLLVSKAQYYAGGESICRNKSLQKMFMLIGFSEKAGSGVNKI
                     FMGWKNANWRPPFVEEQSHPDRVVLNLPMESLYPEEVLEELKRLFGREIERIPYDQFTV
                     LALCYSEKQVSNERLQYILNQHSSNITKLLKSMCNAGFLESIGNGRGTRYRLLFLEKDE
                     SKPQKDESKLKKDESKSQKDESKLEKDESKKYMRYEDLSRLILSVCEDYVALEIIAEAV
                     HREASYLINRVIPRMLEDGLLERLYPSSPKHPLQKYRVRQVGNL"
     CDS             5409..6170
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_59"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.7e-30,
                     bitscore: 97.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQQPTFSIITITYNAERWLERTILSVLSQSYPNIEYILIDGASK
                     DKTVEIIKQYESGIASWISEPDKGLYDAMNKGLKRATGDYVWFLNAGDTLYTADTVQRI
                     VASLKKKVSLPDVIYGETQIVDAEGRSLGMRRLKAPEKLTWKSFRMGMLVCHQSFISKR
                     EIAPLYNTEYRLTADYDWCIQCLRRSKRIHNTRLTLSNFLEEGLSSVNRKASLKERYEV
                     MCKYYGKVSTILLHGWFAVRFYFAKWFKGRV"
     CDS             6194..8698
                     /locus_tag="ctg4_60"
                     /transl_table=11
                     /translation="MRSIMSKWGKHIAAIAVFLVLTVIYFSPAVFEGKVVRQGDTEKAI
                     GMGNSQMDEYEKTAQPGEFSAWSDAMFGGMPYVSGYGNPAPRFPGYLLVEKPLKALGYM
                     DAGMVFTGFVCFYILMCVMGVNWWLAIAGAIAFALASYNLIIIEAGHVTKAYVIAYMPL
                     TLAGMALLFKRKYLWGAVVFLLGVAFSIANTHLQITYYLLLLCFFVYLGYLFNKLKEKA
                     YKELGTVTAIMAGCVILAVLPNAQNMYAQWDLGQNSIRGATELTTTTPSGEKISSGLDK
                     DYAFAWSYGKGELLTLLVPNAYGGSSGGMLGPDSELYKELRAKGAQVGKEVQAPTYWGE
                     KTFTSGPVYFGALVCFLFVLGMFVIRNPMKWWLFGGSVFLILLALGRNFDSFNDFMFHY
                     LPMYNKFRTVEMALVIPGMVFPIIAIWGLKEVLSETVSDALLKKGLIAALAITGGISLI
                     LWLMPSMLLDFRSSFDAQYQLPDWYYNALLMDRASLASADALRSLVFILLGAALLFWFY
                     TSKDRKKVATFVGIGVAVLMLVDLWTVDKRYLNDSNFIRQKPTEVYKETVADQEIMKDK
                     DLSYRVLNLNNPFLETTTSYYHHSVGGYYAAKLRRYQELIDHRLQGELNSVIEAFQKAQ
                     IAEDLMGAFAACPSLNMLNTRYIIYNPEQPPLRNPFAFGNAWFVDKVEVVENADAEIAA
                     LNTINPLTTAVVDKRFADEVKGFTPQLDSTATITLDSYRPNKLVYTTKTNSEQLAVFSE
                     IYYQPGWEATIDGKPAPHFRADWILRAMLVPAGEHQIVFEFRPQGYITAAYITSFSSLI
                     ILLLLIGAIGYSIWRAKKDKTA"
     CDS             complement(8861..9988)
                     /locus_tag="ctg4_61"
                     /transl_table=11
                     /translation="MNKYITYLFLLLLSCGKPQDNNGIFTMDLSKDDLPKTTVSLDDYT
                     TKWTRIDLETTEDCLLDPSFNIYPTDHFIVAYSFNRILVFDHTGHFIREISHFGEGPDE
                     HGLLFNCTVNPTSEQLVFVEMGNTEEIIRYDLSSGKQLTAIPIVAKKQLCDLLFIKDST
                     LVCFPYAGNQKQMAYKQNLAGEWIGTPPIPISEPAGPYNPIPISLFQVDNQWIYKGIYE
                     DTLYLVNNLEPFARFSRKDISPSKTELEVQNSSFINHLFTSNGMSLFGYPQYQLKEVSE
                     GIFDLVLVDFRAFLFNHADKQILEIEKMNCPPLSIIYEQKNLNDLFMLISSRNPKKLVL
                     KVPAEFMGKEEDENPVLFISDLIYPKKKQPTRGKP"
     CDS             complement(10001..11557)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_62"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 5.8e-08,
                     bitscore: 25.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.9e-15, bitscore: 49.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.1e-09, bitscore: 31.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.3e-09, bitscore:
                     27.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLEYKNSPVLGFILNSKYYLYDRYSNSIFTVPRIFFEYLDDLI
                     SLDTDEFTQKYHNIFSKEEIIDLFKTLDYCQNDKKLIKPNRIPKFTISSIYSNAKKVEK
                     KLKKELTFLCINITEECNLRCEYCIFSGKYTKSRRHNSNNQIEWNYIEKGVNLFLEHST
                     DSNIRKIGFYGGEPLLYFDIIRKTINYVRSKCDNAIFTITTNATLLKDKILSFFVENNV
                     EITISLDGPQNIHDKNRIFPNGVGSFNTVIKNIESIKRLHHDFFENNIKFSATLSPGKY
                     KIKDLIDFFTYDMFPTLKRADLPLSLNYINYEENKYLSEVKYLDWTKKTENEIFKLYKK
                     IHIKGINKTSEIPAVLRALPIHREMMYINLRSNIAFDEFKFFWPNGACIPGMRSIFLNS
                     KGIFLPCEKLNSETEFCIGDVSTGFDIKKISQLIADYSREIAPLCSNCWAFRFCGECWT
                     TAVKNGQISKDFRSQYCSYIKSYWARRLFLYTEIIEKNPKAFSYQGSIDYPEFMSHMIN
                     E"
     CDS             complement(11601..11774)
                     /locus_tag="ctg4_63"
                     /transl_table=11
                     /translation="MKQKTKKISWENFKDEIKVISAGQQKLLTGGGCACCICSPGNGNS
                     GLGGSTKASISH"
     CDS             complement(11795..12607)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_64"
                     /sec_met_domain="TIGR04085 (E-value: 6.2e-11, bitscore:
                     34.9, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-07, bitscore: 24.1,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFHITISFDGEKEIQGLNRLSKDKKNSFDIVYNNIRKIQLNNTRY
                     FEQYVTINSVYSINITSSLSEFTNYLEAHFKNKFAINIQSSEINDEYTKFHNNFTKSFL
                     SIYENIHIQGFENSSPPLFIISSDLHKKMMFFSRRSNNILQEETRFIPIKSCLPYLNKI
                     YISPTGDIFMCSDLYYIKGFNIGNIDKSIELNKLQDIMTQYTNFRNKTCKKCWVYRFCD
                     FCFYTLYASKERKGINKYCKIIKYDYAQVIKSYIKILKSNGSAFDIYY"
     CDS             12660..12794
                     /locus_tag="ctg4_65"
                     /transl_table=11
                     /translation="MIVNDTLLLNVFMYSTIFFIKLNLSRGSPPMNDIWWLQLLLFLK"
     CDS             complement(12850..13179)
                     /locus_tag="ctg4_66"
                     /transl_table=11
                     /translation="MEDLFKTYKRNVALGINIDNLYYIYDRSSNNILEVSKYIYENLDY
                     LSLFESSIENIFINKKLSANYFNQWIPKLNTLKQNIDNTLSELTLNITETCNFRCKYCF
                     FNKKK"
     CDS             complement(13191..14033)
                     /locus_tag="ctg4_67"
                     /transl_table=11
                     /translation="MRKQILIICIYIGELPWYFKFFLKSCSFNKDIDFLILCDQDMTSK
                     GISNNIKIKRYDLQDFKKDVHRSLNINTPIQNGYKLCDFKPAYGYIFSRYIEGYDFWGY
                     CDIDVIFGNIRAFITENILSKYEIITVRQDYLSGCFTLFKNEHKTNTLFMQSKNYLKVF
                     LSEKNFCFDETNFAFDEFAKSKDAYNINTEIESMTHVVLKMKDKGLLKPYFNLHILEGL
                     PGNMTWKKGTLLYKNKYEVLLYHLIFFKDFFKQYNKSTVPDEFIIEQTRITEISAFSY"
     CDS             complement(14177..15304)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 98.1;
                     E-value: 1.1e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_68"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.1e-18,
                     bitscore: 59.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFAILSPIYPYRGGIAQFSGMLYTELVKEGHEVKAFNFKRLYPD
                     ILFPGKTQYVEAGDRAIEIESVRVLDSVNPVSYFSTVNAIRSYAPDVLIISYWMSFFVP
                     GYAHVANRMKKHCKVITLIHNAIPHEPRFFDKPLASLLFKQCHGFIVMSDNVRYDLRKL
                     YPGAKYIQNPHPLYNHFGSKINKNEACRKLGIHPSKKNLLFFGLIRDYKGLDLLIEAMG
                     QLNEDYHLIIAGECYGSFEKYQALIDASPAKERIFVHCEYISDEEIPIYFSAADALVLP
                     YRSATQSGVVSVAYNYDLPMLSTPVGDFKNSIEKPGTGIVVPEISATALAQGIEELFTP
                     SQQATIPANISKEKAALSWETLTRKLLDFINSGFI"
     CDS             complement(15407..16780)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_69"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.7e-08, bitscore:
                     26.3, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLAEFGRKEIEIAEHEMPGLMALRQKYADQKPLKGARITGSLHM
                     TIQTAVLIETLVALGADVRWASCNIFSTQDHAAAAIAADGVPVFAWKGETLEEYWWCTD
                     MALRFPEGKGPHMIVDDGGDASLLIHMGYRAENDAETINRKGGNHEEQVILDTLNRILQ
                     EDNGRWHRTVAEMKGVSEETTTGVHRLYQMMEKGELLVPAINVNDSVTKSKFDNLYGCR
                     ESLADGIKRATDVMIAGKVVVVAGYGDVGKGCSHSMRSYGARVLVTEIDPICALQAAME
                     GFEVTTMEEAVKEGNIFVTTTGNCDIITIEHMTQMKDQAIVCNIGHFDNEIQVDKLVNY
                     PNIKHTNIKPQVDKYTFPNGNSIFLLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQMDL
                     WQMAYEVGVYRLPKRLDEEVARLHLERIGVKLSTLSQKQADYIGVPVEGPYKADHYRY"
     CDS             complement(17011..17772)
                     /NRPS_PKS="Domain: PKS_KR (10-164). E-value: 2.3e-16.
                     Score: 52.1. Matches aSDomain:
                     nrpspksdomains_ctg4_70_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     226.9; E-value: 4.5e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_70"
                     /sec_met_domain="adh_short (E-value: 2.2e-37, bitscore:
                     121.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.7e-31, bitscore:
                     101.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMTKTTEEKVALVTGSAMGIGLACAEAFAKAGYITVLADIREPR
                     EQVEKLVAEGHKAVAYRCDVSNTQAVKEMIDWIVATYGRLDAALNNAGIQTPQRPMAEI
                     TDDEFDRTVAVDLKGVWNCMRYEILQMLKQGGGAIVNTSSQGGVTGFPGQAAYIACKHA
                     VIGLTRTAAIDYAAKNIRINAVCPGVIRTPMAEDLMRRDPSLEKELVRDIPAGRLGKPE
                     EIANAVLWLCSPQASFVDGHALLVDGAFSIH"
     aSDomain        complement(17281..17742)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_70_PKS_KR.1"
                     /evalue="2.30E-16"
                     /label="ctg4_70_PKS_KR.1"
                     /locus_tag="ctg4_70"
                     /protein_end="164"
                     /protein_start="10"
                     /score="52.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGSAMGIGLACAEAFAKAGYITVLADIREPREQVEKLVAEG
                     HKAVAYRCDVSNTQAVKEMIDWIVATYGRLDAALNNAGIQTPQRPMAEITDDEFDRTVA
                     VDLKGVWNCMRYEILQMLKQGGGAIVNTSSQGGVTGFPGQAAYIACKHAV"
     CDS_motif       complement(17296..17355)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_70_0001"
                     /evalue="2.10E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg4_70"
                     /protein_end="159"
                     /protein_start="139"
                     /score="13.8"
                     /tool="antismash"
                     /translation="VNTSSQGGVTGFPGQAAYIA"
     CDS             complement(17876..18694)
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 53.5; E-value: 3.3e-16)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_71"
                     /transl_table=11
                     /translation="MDGINTLRYSDLFLAMYFDGGKSCLHRNHSHVLVYVYSGEMVIDE
                     KGQITRLHKGECAFIRKDFSVQMTKQAWNGEQFKAIFLMFTMKFLRDFYSKLDRNTLPK
                     DAKRDQVSLYKLPSNRPDIVSLFESMTPYFNSKIQPTDELLQLKMVEGVYVLLNTDKNL
                     YASIFDFTDPWKIDILEFMERNYMNDISMEEIANYTGRSLSTFKRDFKKCSALSPREWL
                     IRRRLEAAHGLIRKGGRKVSEICFEVGFKNLSHFSKIYKIAYGVPPTEDI"
     CDS             complement(18788..20437)
                     /NRPS_PKS="Domain: AMP-binding (11-443). E-value: 1e-97.
                     Score: 319.2. Matches aSDomain:
                     nrpspksdomains_ctg4_72_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     380.5; E-value: 1.7e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_72"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-108, bitscore:
                     355.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELHNRTLGQWLEHWAENTPDKEYIVYSDRDLRFTWSEFNKRVDD
                     MAKGMLAIGITHGTHVGVWATNVPDWLTFLYAGAKIGAVLVTINTNYKQSELEYLVENA
                     DIHTMCITDGVFDGSYVDMVYTMLPELKTSQRGYLKSERFPRLRNVVYIGQEKYRGMYN
                     TPEMLLLGQNIKDETLEAAKARVNCHDVVNMQYTSGTTGFPKGVMLTHYNIANNGFLTG
                     EHMKFTADDKLCCCVPLFHCFGVVLASMNVLTHGCTQVMVEKFDPLLVLASIHKERCTA
                     VYGVPTMFIAELNHPMFEMFDLTSLRTGIMAGSLCPVELMKTVDEKMHMRVTSVYGLTE
                     TSPGMTHSRIEDPAEVRYNTVGHEFEFTEVRVIDPETGEECPVGVQGEMCNRGYNNMKG
                     YYKNEAATNEAIDKDGFLHSGDLGVRDENGNFRITGRIKDMIIRGGENIYPRELEEFLY
                     HFPGVKDVQVAAVPSKKYGEEVGAFIILHDGVTATEEEVKDFCRGKIARHKIPKYIFFV
                     DTFPMTGSGKIQKFKLKDLGLKLLQEQGITPA"
     aSDomain        complement(19109..20404)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_72_AMP-binding.1"
                     /evalue="1.00E-97"
                     /label="ctg4_72_AMP-binding.1"
                     /locus_tag="ctg4_72"
                     /protein_end="443"
                     /protein_start="11"
                     /score="319.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LEHWAENTPDKEYIVYSDRDLRFTWSEFNKRVDDMAKGMLAIGIT
                     HGTHVGVWATNVPDWLTFLYAGAKIGAVLVTINTNYKQSELEYLVENADIHTMCITDGV
                     FDGSYVDMVYTMLPELKTSQRGYLKSERFPRLRNVVYIGQEKYRGMYNTPEMLLLGQNI
                     KDETLEAAKARVNCHDVVNMQYTSGTTGFPKGVMLTHYNIANNGFLTGEHMKFTADDKL
                     CCCVPLFHCFGVVLASMNVLTHGCTQVMVEKFDPLLVLASIHKERCTAVYGVPTMFIAE
                     LNHPMFEMFDLTSLRTGIMAGSLCPVELMKTVDEKMHMRVTSVYGLTETSPGMTHSRIE
                     DPAEVRYNTVGHEFEFTEVRVIDPETGEECPVGVQGEMCNRGYNNMKGYYKNEAATNEA
                     IDKDGFLHSGDLGVRDENGNFRITGRIKDMIIR"
     CDS_motif       complement(19208..19294)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_72_0002"
                     /evalue="1.40E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_72"
                     /protein_end="410"
                     /protein_start="381"
                     /score="11.2"
                     /tool="antismash"
                     /translation="PVGVQGEMCNRGYNNMKGYYKNEAATNEA"
     CDS_motif       complement(19805..19855)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_72_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_72"
                     /protein_end="211"
                     /protein_start="194"
                     /score="23.3"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     CDS             complement(20450..21031)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 92.5; E-value: 6.5e-28)"
                     /gene_kind="other"
                     /locus_tag="ctg4_73"
                     /transl_table=11
                     /translation="MGNNKIIGAKIKNIRESKQLSIEEVAERSGLGIEQIERIEGNLDF
                     PSLAPLIKIARVLGVRLGTFLDDQAELGPVVCRKKDSEADGIGFTNNATQGHKHMDYHS
                     LSQDKSGRHMEPFLIEIAPSEEGEDFILSTHEGEEFIYVLNGVVEINYGKNTYILEEGD
                     SIYYDSIVAHHVHAAADNKARILGVVYTPY"
     CDS             complement(21191..21460)
                     /locus_tag="ctg4_74"
                     /transl_table=11
                     /translation="MYLDSAKKKELFEKYGKSATNTGSAESQIALFTFRISHLTEHLKV
                     NHKDYATERSLKMLVGKRRRLLDYLIKTDIERYRAIIKELGIRK"
ORIGIN
        1 ctgttttgat ggattttctt tcagaaaatg aagctgtgtt taaaaattca gttcgattga
       61 ttgaacagga gaacaaaggt gtttctgcag cgaggaacca aggtattaaa gaagctagag
      121 gtgagattat tgcctttctt gatgctgatg acgagtggtt acctgattat ttaaaaacta
      181 tcgctttctt ggttgaaaaa tatccggaat gtgatatttt tggtacagct tattcattta
      241 agatgaataa tatgataact cccgcatcaa ttgattatta ttcttttaaa gagaatgagg
      301 gtattttaga taattatttt acgatggcct caaaagcgag aggacctatt tggacttcag
      361 ctgtggctgt tcgaaaaaag gctattttat ctattggttg tttccctgag ggcatttctt
      421 taggtgaaga tgtaatcgtt tgggctaaat tagcttgctt gtataaaata gcttattcga
      481 aatcaaacct agcattgtat agaagagata gcagttgcta tttgagtgtt aagaaaaata
      541 tgcagccagc aataaaagaa gactatgttg gtatagagct ttggaggcta aactgctctt
      601 atcagataaa agacttagat aattatgttt atctttggta caagataaga tttgtaatct
      661 ttgtttttga taatgataag aaaagtgcat ttttggagta tatacgttta ttgccttggg
      721 gattattgaa tttggattgt aactatcatt tgtttttaaa ttgtttacca tattccttgt
      781 tagttaaatt aaatacttgt gttcggagga tatttagaaa aaaagtttga tataatttta
      841 gattatggaa gaaaaccaac ataccgaatt caaagagtca tggcatgacg aatatacccg
      901 ttatatatca gctttctgta atacggaggg tggtgtatta tatatcggta tcgatgataa
      961 aggagaagtt gtagggatag agcagccaaa gaagttgatt gagaaactgc cgaactttat
     1021 cgctcagaaa acgggtatta tgcctcttat ccatttgagg gagaaggccg gtaaagaata
     1081 tttggaaata gaagtccaac cttctgccat gccgatttcc gtgcatggac ggtattatac
     1141 ccggagtgga agcgttactt ccgagctaca agggaatcag ctaaatatgt ttttggctgc
     1201 gaaaatgggt ttgacatggg aaagtgtgat cgaggaggat ttctcattgg aggacataga
     1261 taccgatacg gtagaacgtt ttaagctatt ggctaaagac cgggttcctt ccatcgagca
     1321 ggaaacggat ctgctggctt tgatggagcg gttgaatttg atcgtaggag gccgtttcaa
     1381 gagagccgct gtagtcttgt ttggaaagaa tgtgcagaga tatgtgttac aagctcgtat
     1441 taaaatagga aagttcctta ccgatacgga ggtactgaca accgatattg tcgaggggaa
     1501 cctgattcag caggttgatc gggctttgga tatattgcga acgaaatatt tattaagtta
     1561 tatatcgtat gaggggattc ataggcgtga gaaactggtt tatccctacg aggctctgcg
     1621 ggaagcctta ttgaattcga ttatccatcg agaatatttt gtttcttccg aaattcaggt
     1681 acgtgtttac gaggacaagc tggtgatagg gaatgaagct cgtttgcacg atattacggt
     1741 tgaggacttg tctcgtcctc acccctctag acctcataat aagttgatag cggatgtttt
     1801 ttacaaagct ggctttatcg agagttgggg acggggaaca caacgtatta ttgacaactg
     1861 cttggcagaa ggattatccg ctcctgtata tgagcataag atgggttttt tatacttgac
     1921 tttttttcat gagcggataa atgagcggat aaatgagcgg ataaatgagc ggataaatga
     1981 attgtcggat atggaacggg aggtatatca gatcttgcga gaggagccta ctatccgtca
     2041 aatagattta gcaaatcgtt tggatttgac agagcagtat atccggaagc ttataaaaaa
     2101 gttgaaagag catggttgga ttgaacgcat tggagctagg aaaaatggtt attggaaaat
     2161 aatagagaag tcatgaagat attgatatta aatacctctg aattaaccgg tggagcggca
     2221 gtcgccgcaa accgactagc gaaagcattg ggtaaatctg gtgtagaggt ttctatgtta
     2281 gtacgtgatc ggaaaacaga ccatgtaaaa gttttctctg taaataattc atggacttca
     2341 cataggctta attcttttcg cttcatttgg gaacgactga taatctttat ctgtaacttc
     2401 tttagcaaga agaacctctt tcaagtttcc atagccaata caggcacgga tttatcgaag
     2461 cacccattag tgcaacaggc ggatgtgatt catctgcatt gggtgaatca aggatttttg
     2521 tctctttctg atattaagaa attagtaaat accggaaaac ctattgtgtg gactatgcat
     2581 gatttgtggc cagctacggc tatttgtcat tatccgggag gatgtgagaa gtatatatcg
     2641 aattgttatc agtgcccgat gctgaaacga aatccgtttt ttgatttagc ggcttctgtt
     2701 tttaaggaga aagggaaaat agggttatct aagattacat ttgtcggttg tagccgatgg
     2761 ataatggaag aggcccaaaa aggcaattgg ttgagaacag cctgttttac ctcgattcct
     2821 aacccgattg acgtgacagc ctttaagcgt atggaaaagc gggtggcccg taaacgattc
     2881 gacctgccgg aaggtaagtt ccttcttctt tttgccgccg ctaagctttc agatacccgg
     2941 aaaggagcga tttttttgat cgaggcttgc gaaaaactaa aagagaaata ccaagatcgc
     3001 atagaaatcg tgttgatggg aaatagctcg gaagaattga ttagccagtt tccttttaag
     3061 gtgaatacgc tgggatatat atcggatcaa gactctatga tttccgttta tgcctgtgcc
     3121 gatatgttcg ttattccttc gttggaggat aacttaccca atacgattat ggagtcgatg
     3181 gcatgcggta cgccttgtgt gggatttgag acaggaggga ttccggagat gatagatcat
     3241 ttgaagaatg ggtatgtagc taaatataag gatacaaatg atttggctgt agggattaag
     3301 tggataattg acaaccaaga gacttttcga tttagtgagg cttgcgtccg caaggtgcat
     3361 gattgctata gggaatcggt tattgccgaa aaatatatag ctttgtatca gagcctgtgt
     3421 aataagagaa aatagcgtga aagaagatca gcatatcgaa gtaagaatga atgcttgctg
     3481 gtaagtgatt gaaagcaaat gaaaattgct acatttgtgg aaaaatggaa taaatggacg
     3541 atcagcataa gcctgaatgg attaaggtgg acgagtggga ttttgtagaa tatgtggata
     3601 gcttgttgcg tagtcaagag gctgtcgatt tagagtttaa gaccgctcgt gccggattcc
     3661 caaatagtgt gtgggaaacg tattcttcat ttgcgaatac agatggagga actatcgttc
     3721 tgggaataaa ggagaaaaat ggggcactat ttgtggaggg acttcttcca gagcaaattg
     3781 tgtcttatcg gcaaatcatt tgtaaccaat tgaataatcc ggattgcgtt aatgttaatt
     3841 tacttactga caagaatatt caagaggtag actatagagg aaaatctctt ttgctgattt
     3901 atgttccgag agcatctcgt tcacaacgtc ctgtatattt aacaagaaat cccttgaatg
     3961 gacatactta taaacgaaat aatgagggag attataaatg tacggatacg gaagttcgca
     4021 gaatgattgc cgatgcggat gaggaacatc cgagagattc tcgtatttta tgtaattatt
     4081 caatggaaga tattgatttg gactcactta aacaatatcg actgctactt tctagtcgtc
     4141 agccagatca cccttggttg acacttgatg atatggcttt tttgagaaaa ttgggaggat
     4201 atcgacaaga taggcaaaca ggtcaagaag ggtttacttt agcgggtata ttaatgtttg
     4261 gaaggacaga aagtataacg gataatgaat gtgctccatc ttattttccg gattatcagg
     4321 aaaaaatgtc ggtagatgag aatgttagat ggacagatcg catttgtatg gatggaactt
     4381 gggaagcgaa tctttttcaa ttttatcggc gtgtgtatcc taaattatca tctgtactgc
     4441 ctaagccatt ccgtttggag aatggtgtga gattggaaga tactaccacg catgtcgctt
     4501 tacgtgaggc atttgtaaat acattggtgc attgtgatta tatggaggaa ggaaatataa
     4561 cgatagaaca atggaaagat cgttatgtat ttaaaaatcc cggaacactg ctagtgagta
     4621 aggcccagta ttatgccgga ggtgaaagta tatgccgtaa taagagcttg caaaagatgt
     4681 ttatgctgat tggcttctct gagaaagcag gaagtggggt gaataagatt tttatgggtt
     4741 ggaaaaatgc gaattggaga cctccatttg tggaggagca aagtcacccg gatcgggtgg
     4801 tgttgaattt accgatggaa agtttgtatc cagaggaagt cttagaagaa cttaagcgtc
     4861 tgtttggacg ggaaattgaa agaattccat atgatcaatt cacggttttg gctctttgtt
     4921 actctgaaaa acaagtatct aatgaaagac ttcaatatat tttgaaccaa catagctcaa
     4981 atattacaaa gctactaaaa agtatgtgca atgctggttt tttggagtct ataggaaatg
     5041 gccggggaac taggtaccgt ttgctgtttt tggagaagga tgaaagcaag cctcaaaagg
     5101 atgaaagcaa actgaagaag gatgaaagca agtctcaaaa agatgaaagc aaactggaga
     5161 aggatgaaag taagaaatat atgcgttatg aggatttgtc gaggttaata ctatctgttt
     5221 gtgaggatta tgtagctctg gaaataatag cggaagctgt tcatagagag gcttcttatt
     5281 taattaatcg ggttatacca agaatgttag aggatgggct actagagaga ttatatccgt
     5341 cttctcctaa gcatccttta caaaaatatc gtgtgagaca agtcggaaat ttataagaga
     5401 taatggaaat gaatcagcaa cctacatttt cgatcataac gatcacctat aatgcggagc
     5461 gatggttgga gcgtacgata ttgagcgtac ttagccagtc gtatccgaat atcgagtata
     5521 tattgattga cggagcgtcg aaggataaga ccgtagagat catcaagcaa tatgagtccg
     5581 gtatcgcttc ttggataagc gagcctgata aaggcttgta tgatgctatg aataagggat
     5641 tgaagcgggc tacgggggat tatgtgtggt tcctgaatgc gggggataca ctttataccg
     5701 cagataccgt gcaaagaatt gtggcgtctt tgaaaaagaa agtatctttg ccagacgtga
     5761 tttacggaga gacccagatc gttgatgcgg agggtagatc attagggatg cgcagattga
     5821 aagcaccgga gaaactgact tggaaaagtt tccggatggg aatgttggtt tgtcaccagt
     5881 cgtttatatc aaaacgggag atcgctccgt tatataatac ggaataccgt ttgacggcgg
     5941 attatgattg gtgtatccaa tgtctgagac gatcgaaaag aatacataat acacgtttga
     6001 ccctgtctaa ttttttagag gaaggattaa gtagtgtgaa ccggaaagct tccttaaagg
     6061 agcgatatga ggtcatgtgt aagtattatg gcaaggtgtc gacgattctg ttgcatggtt
     6121 ggttcgccgt gagattctat tttgccaaat ggtttaaagg tagagtataa acaataaatt
     6181 atagataagt tttatgcgga gtataatgag taaatgggga aaacatatcg cagcgatagc
     6241 cgtattcttg gtattgacgg tgatttattt ttctccggcc gtatttgagg gtaaggtagt
     6301 ccggcaaggg gatacggaaa aggctatcgg tatggggaat agccagatgg atgaatatga
     6361 gaagacggcc caaccgggag aattcagcgc atggtctgat gctatgtttg gcggaatgcc
     6421 ttatgtgtcg ggatatggaa atccggctcc acgatttccc ggatatcttt tagtggagaa
     6481 gcctttaaaa gcgctggggt atatggatgc ggggatggtg tttaccggat tcgtttgttt
     6541 ctatatcttg atgtgtgtca tgggcgtaaa ttggtggttg gcgatcgctg gtgctatcgc
     6601 tttcgcttta gcatcttata atctgatcat tatagaggcc ggccatgtca cgaaagcgta
     6661 tgtaatcgct tatatgccat taacgttggc gggtatggcc ctgttgttca agcgtaagta
     6721 tttatggggg gcggtcgtgt tcttgttggg tgtcgcattc tctatcgcga atacgcacct
     6781 gcaaatcact tattatttat tattactttg cttcttcgtt tatttgggat atttgttcaa
     6841 taaactgaag gaaaaagctt ataaagaact gggtacggta accgctatta tggctggatg
     6901 cgtgatattg gcggtgttgc cgaatgccca gaatatgtat gctcaatggg atttgggaca
     6961 gaactctatc cgtggggcta cggaattaac gacaacgacc ccttcgggcg agaagatttc
     7021 ttccggctta gacaaggatt atgcgttcgc ttggagctat ggaaaagggg agttgttgac
     7081 cttgttggtc ccgaatgcct atggtggaag ttcaggtgga atgctaggcc cggattctga
     7141 gctatataag gaattaaggg cgaaaggcgc tcaagtcgga aaagaggtac aggctcctac
     7201 ctattgggga gagaagacat ttacttccgg gccggtttat ttcggggcat tggtctgctt
     7261 cttgtttgtt ctgggaatgt tcgtgatccg gaatccgatg aaatggtggt tattcggagg
     7321 ttctgtcttt ttgatattgc tggcattggg acgtaatttt gatagcttca atgactttat
     7381 gttccattac ttgccgatgt ataataagtt ccgtaccgta gagatggcat tggttattcc
     7441 gggtatggta tttcctatta tcgctatatg gggattgaaa gaggtgttat ccgagaccgt
     7501 gagcgatgcc ttgttgaaga aaggattgat cgctgctttg gctatcacgg ggggcatttc
     7561 tttaatcctt tggttgatgc cgagtatgct gttggatttc cgttcttctt tcgacgctca
     7621 atatcagttg ccagattggt attacaacgc cttgttaatg gatcgtgctt ccttggcttc
     7681 ggcggatgcg ttgcgctctt tggtctttat cttattaggg gcggctttgt tgttctggtt
     7741 ctatacctcg aaagatcgga aaaaggtggc gacattcgta gggatcggtg ttgcggtctt
     7801 gatgttggtt gacttatgga cggtggataa acggtatttg aacgatagta actttatccg
     7861 ccagaaacct acagaggtat ataaagagac ggtagccgat caagaaatca tgaaggataa
     7921 ggacctttct tatcgtgtct tgaatttgaa taatcctttc ttggagacaa cgacctcgta
     7981 ctatcaccat tccgttggtg gttattatgc cgcgaagctg agacggtacc aagaactgat
     8041 cgaccaccgt ctgcaaggag agcttaactc ggttatcgag gctttccaga aagcgcagat
     8101 cgcggaggat ttgatggggg cgttcgctgc ttgcccgtcc ttgaatatgc taaatacacg
     8161 ttatattatc tataatccgg agcaaccgcc tttgaggaat ccgttcgctt tcggcaacgc
     8221 ttggtttgtg gataaagtgg aggtcgtgga gaatgcggat gcggaaatag cggcgttgaa
     8281 tacgattaat ccgttaacga cggcggttgt cgataaacgt ttcgctgatg aggtgaaagg
     8341 tttcacgcct caattggact ctaccgctac gataacattg gatagttatc gccctaataa
     8401 gttagtttat acgacgaaga ctaattctga gcaattagca gtattctctg agatctatta
     8461 tcaaccggga tgggaggcta cgattgatgg gaagcccgct cctcatttcc gggcggattg
     8521 gatattaagg gctatgttag ttcctgcggg agagcatcag atcgtatttg agtttagacc
     8581 gcaaggttat attacggcgg cttatataac ctcatttagt tcattgataa tccttttgtt
     8641 attgattgga gcgatcggtt actcgatctg gagagctaaa aaagacaaga cagcctaaat
     8701 atccagttgt agagacgggg cgtgccccgt ctcggcacag actaatgggt attttaaagt
     8761 ttccattttg aggagatgag acggggcacg ccccgtctct acaactaggt ggaaattggt
     8821 aacgattatt cgttatggat aaagccaagc agttttctcg ttagggtttc ccacgagtgg
     8881 gctgcttttt ctttggatat atcaagtcgg atatgaataa gactgggttt tcatcttctt
     8941 cttttcccat gaattccgct ggaactttta gtaccaattt cttcgggttc cgggaggaga
     9001 tcagcatgaa tagatcattt aaattttttt gttcataaat aattgacaga ggtgggcagt
     9061 tcattttttc tatttcaaga atttgtttgt ctgcgtgatt aaaaaggaag gctcgaaaat
     9121 caactaaaac taaatcgaat atgccttcag atacttcttt taactgatat tgcgggtatc
     9181 cgaataatga cattccgtta gaggtaaaca gatgatttat aaaagagctg ttctgtacct
     9241 ctaattctgt ttttgatgga ctgatgtctt tccttgaaaa acgagcgaaa ggttctaaat
     9301 tattcactaa gtaaagcgtg tcttcgtaga tccctttata gatccattga ttatccactt
     9361 gaaatagact gataggtatg ggattatatg gacctgccgg ttcggagatg ggaatggggg
     9421 gtgttccaat ccattccccg gctagatttt gtttgtaggc catttgcttt tgattgcctg
     9481 cgtatgggaa gcagacaagt gtagagtcct tgataaataa taagtcacat aactgctttt
     9541 ttgcgacgat tggtatcgca gtcaattgtt tgccactcga tagatcataa cgaattattt
     9601 cttcggtatt tcccatttct acgaagacaa gttgttcact cgtaggattg actgtacagt
     9661 tgaataaaag accatgttcg tcgggacctt ctccgaaatg ggagatctcg cggataaaat
     9721 gtcctgtatg gtcgaatacg aggattcgat taaaggaata agcgacaata aaatgatctg
     9781 tagggtagat gttaaacgat ggatcaagta ggcaatcttc agtagtctca agatctatcc
     9841 ttgtccattt ggttgtataa tcatccaatg ataccgttgt tttgggaagg tcatctttgg
     9901 atagatccat tgtgaatata ccgttattat cttggggctt tccgcaagat aataataaaa
     9961 ggaatagata tgtaatgtat ttgttcatgg ttgttttagt ttattcgtta atcatgtgag
    10021 acataaattc aggataatct atacttcctt gataagagaa tgctttggga tttttttcga
    10081 ttatttctgt atacaaaaat agccttcttg cccaataact ttttatataa ctgcaatatt
    10141 gcgatctaaa atcttttgat atttgtccat tctttactgc ggttgtccag cattccccac
    10201 aaaacctaaa tgcccagcag ttggaacata gtggagctat ttctcttgag taatctgcta
    10261 tgagttgtga tatttttttt atgtcaaatc ctgttgatac atcacctatg caaaactctg
    10321 tttctgaatt tagtttctcg catggcaaaa agatcccttt agaattcaag aaaatacttc
    10381 tcatcccagg tatgcaggct ccattaggcc aaaagaactt aaattcatca aaagctatat
    10441 tacttcttaa attgatatac atcatttctc gatgaatagg tagggctctt agaactgctg
    10501 gtatttcaga agttttattg attcctttta tatggatttt tttatataac ttaaaaattt
    10561 cgttttcagt tttttttgtc caatctaaat attttacttc gcttaaatat ttattttctt
    10621 cgtaatttat ataattaaga cttaatggaa ggtctgctct tttcagcgta gggaacatat
    10681 cgtatgtaaa aaagtcaatt aaatctttga ttttgtattt cccaggtgat aatgtcgctg
    10741 agaattttat attattttca aaaaaatcat gatgtaatcg tttgatagat tctatgtttt
    10801 ttatgacggt gttaaaactc ccaacgccat taggaaaaat cctgttttta tcatgaatgt
    10861 tttgaggacc atctaggcta atggtgatct ctacattatt ttctacaaag aaagacaaaa
    10921 ttttgtcttt tagtaaagtt gcatttgtgg taattgtgaa aattgcgtta tcacatttac
    10981 ttcggacata attgatagtt tttcttatta tgtcaaaata tagaagaggt tcgcctccat
    11041 agaaacctat ttttctaata ttagagtctg tgctgtgttc taagaataaa ttaacacctt
    11101 tttctatata attccactcg atttgattgt tgctgttatg tcttcttgat ttcgtatatt
    11161 tcccagagaa tatgcagtac tcgcatctga gattacattc ttcagttata tttatgcata
    11221 ggaaggttaa ttcttttttg agtttctttt ctactttttt agcgttagaa tagatggatg
    11281 aaatggtgaa tttaggtatt ctattaggtt ttattagttt tttgtcgttt tggcaataat
    11341 ctaatgtctt aaatagatct ataatctcct cttttgaaaa aatattatga tatttttgag
    11401 tgaattcatc tgtgtcaagg ctaattagat cgtctaaata ctcaaaaaat attcttggaa
    11461 ctgtaaaaat ggaattggaa tatctatcgt ataggtaata ttttgaattt aaaatgaaac
    11521 ctagtactgg gctatttttg tattctagtt tttccataaa gtgaaagctt atgcggggag
    11581 agaaatctcc ccgcaggtta ttaatgtgaa attgaagctt tggttgagcc tcctaaaccg
    11641 ctattcccat tacctgggct acagatgcag caagcacatc cacctccggt gagtaacttt
    11701 tgctgtccgg cagagattac tttaatctcg tctttaaagt tttcccatga gattttcttc
    11761 gttttttgtt tcatacgctg aataatttta tatgttagta atatatatca aacgcactcc
    11821 cgtttgattt taatatctta atatatgatt tgatgacttg ggcgtaatca tattttatta
    11881 ttttacaata tttatttatt ccttttcgtt ctttagaagc atataatgta taaaaacaaa
    11941 aatcgcagaa tctataaacc caacattttt tacatgtttt atttctgaag ttagtgtatt
    12001 gtgtcattat atcttgtagc ttgtttaatt ctatagattt atcaatattt ccgatattaa
    12061 atccttttat gtaatataaa tcgctgcaca tgaaaatgtc acctgtcggt gatatatata
    12121 tcttgtttaa gtaaggaagg cagcttttta tgggaataaa tcttgtttct tcttgcagga
    12181 tgttgtttga tcttcttgaa aagaacatca tctttttatg taagtcgctg gaaattataa
    12241 ataaaggggg ggagctattt tcgaatcctt gtatgtgtat attttcatat attgataaaa
    12301 aggattttgt gaaattatta tggaatttcg tgtattcatc gtttatctca gatgattgaa
    12361 tatttatagc aaatttattt ttgaaatgtg cttctagata gttggtgaat tcggaaaggg
    12421 aacttgttat attgattgaa tatacggaat ttattgttac atattgttcg aagtatcttg
    12481 tgttgtttag ttgtattttg cgtatattgt tatatactat atcaaaactg ttttttttat
    12541 cttttgataa tctgttcaat ccttgaattt ctttttctcc atcaaaactt atagttatat
    12601 gaaacatgtt ttcaattaga taatttaata tgtcttcttt taataaagag ccatttgtta
    12661 tgattgtgaa tgatactttg ttgttgaatg tttttatgta ttcaacaatt ttttttatta
    12721 agttgaactt gagtagaggc tctcctccta tgaatgatat ttggtggttg caattattgc
    12781 tgtttttgaa ataaaaatca actgcttttt ttgctgtttt taaggacatt gatttggagt
    12841 atgattcttc tatttttttt tgttaaagaa acaatacttg catctgaagt tgcacgtttc
    12901 tgtaatattt agtgttaatt cagataacgt attatctatg ttttgtttta atgtgttgag
    12961 cttaggaatc cattgattaa agtagtttgc tgaaagtttt ttattaataa aaatattttc
    13021 aatggaactt tcaaaaagtg atagataatc tagattttca tagatatatt tactgacttc
    13081 taaaatgtta ttagaagacc tgtcgtatat gtaatatagg ttgtctatat taatacctaa
    13141 tgcaacattc cttttgtatg ttttaaatag atcttccata tgaatagatt ttaatagcta
    13201 aatgcggaaa tctcagttat tcttgtttgc tctataatga attcatccgg tacagtactt
    13261 ttgttatatt gtttgaagaa atctttaaag aatattaggt gatataataa aacctcatac
    13321 ttgtttttat ataatagggt tcctttcttc catgtcatat ttccaggtag tccttcaagg
    13381 atatgaaggt tgaagtatgg ctttaataag cctttatctt tcatttttaa tacaacatga
    13441 gtcatgcttt ctatctctgt atttatatta tatgcatctt ttgattttgc aaattcatca
    13501 aaagcaaagt ttgtttcgtc aaagcaaaag tttttttcag atagaaaaac ttttagataa
    13561 tttttgcttt gcataaatag tgtgtttgtt ttatgttcgt tcttgaacaa tgtaaaacac
    13621 ccggataaat aatcttgacg gacagttata atttcatatt tagaaagtat attttctgtt
    13681 ataaatgctc ttatattccc aaaaatgaca tcaatatcac agtatcccca aaaatcatag
    13741 ccttctatat atctagaaaa tatgtaacca tatgccggtt taaaatcaca tagtttgtat
    13801 ccattttgaa ttggagtatt gatgtttaaa gatctatgaa catctttttt aaagtcttgt
    13861 agatcatatc ttttgatttt aatattgtta gagatccctt tactagtcat gtcttgatcg
    13921 caaaggatga gaaagtcaat gtccttgttg aaggaacaag attttaggaa gaatttaaaa
    13981 taccaaggta attctcctat gtagatgcat attatcaata tttgttttct cattcttgta
    14041 tttaacgtga tttcgcaatg taatgatttt agagaaataa gtatgtatgt cttttatttt
    14101 ttttgcgtta aaaaaataaa atgcatctat ctgtgctgtt tgaagagaat gtcaagtgga
    14161 aaatagtcag taagtcctag atgaaaccgc tattgataaa atcgagcagt tttctcgtta
    14221 gggtttccca cgagagggct gctttttctt tggatatgtt cgcagggatg gtggcttgct
    14281 gtgagggggt gaaaagttcc tcgatacctt gggcgagggc cgttgcggat atctcaggca
    14341 ctacgatgcc tgtacccggc ttttcgatgc tgttcttgaa atcgcctacg ggagtactta
    14401 acataggtaa atcgtaattg taggctacgg atacgacacc gctttgagtg gcggagcgat
    14461 aggggagtac caaggcatcc gccgctgaga aataaatggg gatttcctcg tcgctgatat
    14521 attcacagtg gacgaatata cgttcttttg ccggagatgc atcgatcaga gcctgatact
    14581 tctcgaaact accgtaacat tcgccggcta taatgagatg gtaatcctcg ttaagctgtc
    14641 ccatcgcttc tatcagcaga tctaatcctt tataatcccg tatcagtcca aagaatagaa
    14701 gattcttttt ggacggatgg attcctaatt tccggcacgc ctcgttcttg ttgatcttac
    14761 tcccgaaatg attgtaaagc gggtgtgggt tctggatata tttagcgccc gggtaaagtt
    14821 tccgcaaatc ataccgcacg ttatcgctca tcacgataaa gccatggcat tgcttgaaaa
    14881 gtaacgaagc taaaggcttg tcgaagaaac gcggctcatg gggaatcgca ttgtggataa
    14941 gggtgattac cttgcaatgc ttcttcatcc ggttcgctac gtgggcgtat ccgggaacga
    15001 aaaaggacat ccagtaagag ataatcagta cgtccggcgc ataggaacga atggcgttta
    15061 cggtactgaa ataactaacc gggttgacgc tatctaatac tcgcacgctc tcgatttcga
    15121 tcgcacggtc tcccgcttct acgtattgag tcttgccggg aaataagata tccggataaa
    15181 gacgtttgaa gttgaaagcc tttacttcat gaccttcttt tactaattcc gtatagagca
    15241 tcccgctgaa ttgggcgata ccgccacgat agggataaat aggggagaga atagcgaaac
    15301 gcatggtaat tgaaaattaa gaattgaaaa ttgaaaatta agaatcgaga actacaggag
    15361 ctgccctccc ttcattatca attctcaact ttcaatcttc aattaattag tatctgtaat
    15421 gatcagcctt gtacggtcct tctaccggta caccgatata atcagcttgc ttttgtgata
    15481 atgtagataa tttcacgccg atacgttcca agtgtaggcg ggcaacttcc tcatccaagc
    15541 gtttcggtaa gcggtataca cctacctcat aagccatttg ccataagtcc atctgggcaa
    15601 gcacttggtt cgtgaacgag ttactcatta cgaatgacgg gtgtcccgta gcgcaaccta
    15661 agtttaccaa gcgtccctct gccaataaga agatggagtt tccgttcggg aacgtatatt
    15721 tgtccacttg aggtttgata ttcgtgtgct tgatattcgg atagttgaca agcttgtcca
    15781 cttggatctc gttgtcgaag tgaccgatgt tacatacgat cgcttgatct ttcatctgtg
    15841 tcatatgctc gatcgtgatg atatcgcagt ttccggtggt tgtaacgaag atgttaccct
    15901 ctttcacggc ctcttccatg gtcgtaacct cgaaaccttc catagcggct tgcagggcgc
    15961 agatcggatc gatctcggtc acgagtacgc gagccccgta agagcgcatg gagtgagagc
    16021 agcctttacc tacgtcaccg tatccggcca cgactactac cttgccggcg atcatcacgt
    16081 ctgtagcccg tttgatgccg tccgccaaag actcacggca accgtataag ttatcgaact
    16141 tggatttcgt cacggagtca ttaacattga tagccggaac cagcaactca cctttctcca
    16201 tcatctgata cagacggtga acgccggtgg tcgtctcttc cgacacacct ttcatctcgg
    16261 ctaccgtacg gtgccaacgg ccgttatctt cttgaaggat gcgatttaat gtatccagga
    16321 ttacctgttc ctcatgattc ccgcctttgc ggttgatggt ctccgcgtcg ttctccgcac
    16381 gatagcccat gtgaatcagc aaggaagcgt cgccgccatc gtcaacaatc atgtgagggc
    16441 ctttaccttc cggaaaacga agcgccatgt ccgtacacca ccaatattct tccagcgtct
    16501 cgcctttcca agcgaatacc ggtacgccgt ccgccgcgat agcggctgcc gcatggtcct
    16561 gtgtggagaa gatgttacag ctagcccagc gaacgtccgc tcccaacgca actaatgttt
    16621 cgattaacac cgccgtctga atagtcatat gcagtgagcc ggtgatacgt gcgcctttca
    16681 agggtttctg atcggcgtat ttctggcgta gcgccattaa tcccggcatt tcgtgttcgg
    16741 cgatctcgat ctctttgcga ccgaattcag ccaaactcat atctgccact ttataaggca
    16801 gattagttgg aaataattgt gacataaatt aatactataa atggttgaga cgcgaaggta
    16861 cgaaaaagcg ttgatagtag gtgttcttta tctatgaatt tccatctagg gcagaggctt
    16921 gccgaggggt aggtgggttc gttactgcaa cctgccttgc agtagttctg caacagccat
    16981 gcagtattgg gctctctgta gttttgcgct ttaatgaata ctgaaggctc catctaccaa
    17041 tagcgcgtgg ccatcgacga agctcgcttg cgggctgcat agccaaagta cggcgttggc
    17101 gatctcttcc ggtttaccga gccgccctgc gggaatgtcg cgcaccagct ccttctccaa
    17161 ggaagggtca cgccgcatta agtcttccgc catcggcgta cggataacgc ccggacatac
    17221 ggcattgatg cggatgttct ttgccgcata gtcgatagcg gcggtacgtg tcagtccgat
    17281 aacggcatgc ttacaggcta tgtaggccgc ttgccccgga aatcccgtga ctccgccttg
    17341 cgatgaggtg ttgacgatgg ctccgccgcc ttgtttcagc atttgcagga tctcataacg
    17401 catgcagttc cagacacctt tcaaatccac agccacggta cggtcgaatt catcgtcggt
    17461 gatttctgcc attgggcgtt gcggtgtttg tatgcctgcg ttgttaagag ccgcgtccag
    17521 tcttccgtag gtagctacga tccagtcgat catctccttt acggcttgcg tgtttgatac
    17581 gtcgcaccga tacgctacgg ccttatgtcc ctcggctact aatttctcta cctgttctct
    17641 cggctcacgg atgtctgcca atacggttat gtatccagcc ttggcgaagg cttcggcgca
    17701 agcgagtccg atacccatcg cagaaccggt tactaaagct actttctctt ccgttgtctt
    17761 tgtcatgatc atttgattta cattttgtta ttatttatgt cgcgaagata aggagggagt
    17821 ggtatagagg ctttgttatg tggttcaaat agctttgttg tgtgggccat taatattata
    17881 tatcctcggt tggcggtacg ccatacgcta tcttatagat tttcgagaaa tgggaaaggt
    17941 tcttgaagcc tacttcgaaa caaatctccg agaccttacg ccccccttta cgtatcagcc
    18001 cgtgtgcggc ttcaaggcgg cgtcggatga gccattcccg gggcgagaga gcgctacatt
    18061 tcttgaaatc acgtttaaat gtggagagac tgcgtcccgt atagttggcg atttcttcca
    18121 tggaaatatc gttcatgtaa ttccgctcca tgaattccag tatgtctatc ttccatggat
    18181 cggtaaaatc gaagatagag gcatatagat tcttgtcggt attgagcaac acataaacgc
    18241 cctcgaccat ttttagttgc agcaattcgt ctgtcggttg gatcttggaa ttgaaataag
    18301 gggtcatcga ctcaaacaag cttacgatat cgggacggtt ggacggtagc ttgtaaaggc
    18361 ttacctgatc tcgcttggca tctttaggga gagtatttcg atctaatttg ctgtaaaagt
    18421 cgcgtaggaa cttcatggtg aacatcaaga agatcgcctt gaactgctcg ccattccatg
    18481 cttgtttcgt catctgcaca ctgaagtcct tgcggatgaa agcgcattct cctttatgta
    18541 accgggtgat ttggcctttc tcgtcgatta ccatctctcc ggaatataca tacaccaaca
    18601 catgcgaatg attccggtgc aggcagctct tcccgccatc gaaatacatc gctaaaaata
    18661 aatccgagta acgcagcgtg ttgattccgt ccatagttct ttaggaaaat gggcaacacg
    18721 agaagatcgt accgcccatt atgaagattt taaagtaact gtcaactgtt agctgtccac
    18781 taaatcgtca ggccggcgtg ataccttgct cttgcaatag tttcagcccg aggtctttca
    18841 acttgaactt ctgtatcttt ccgcttccgg tcatcgggaa ggtatcgacg aagaagatgt
    18901 atttcgggat cttatgccgg gcgatctttc cgcggcagaa atctttcacc tcttcctccg
    18961 tagccgtcac accatcgtga aggatgataa aggcacccac ttcctctcca tatttcttgg
    19021 aaggaacagc ggctacttgc acgtctttca cgccggggaa atgataaagg aattcctcca
    19081 gctcacgtgg atagatattc tcgcctccac ggataatcat atccttgata cggccggtga
    19141 tacggaagtt tccattctca tcacgaacgc ccaagtcgcc ggaatgcagg aaaccatcct
    19201 tgtcgatcgc ctcattggtg gcggcttcgt ttttatagta acctttcatg ttattataac
    19261 cgcggttaca catctcgccc tgtacgccga cggggcattc ctcgccagtc tccggatcga
    19321 taacccgtac ctcggtaaat tcgaactcat ggcctacagt attataacgc acctcggccg
    19381 gatcttcgat acgggagtgg gtcatacccg gtgaggtctc tgtcaatcca tacacgctgg
    19441 ttacacgcat atgcatcttc tcgtccacgg ttttcatgag ttcaaccggg caaagagaac
    19501 ctgccataat accggtacgt aacgacgtga ggtcgaacat ctcgaacatc gggtggttca
    19561 gctcggcaat gaacatggta ggcacgccgt acacggccgt gcaacgctct ttatgtatag
    19621 aagctaatac caatagcgga tcgaatttct cgaccatcac ttgcgtacat ccatgcgtca
    19681 atacgttcat ggaagctaat accacgccaa agcaatgaaa gagaggtacg cagcaacaaa
    19741 gcttatcgtc ggcggtgaat ttcatatgct cacccgtcaa gaaaccgttg ttggcgatgt
    19801 tgtagtgagt caacatgacc cctttcggga agccggtcgt accggaagta tattgcatat
    19861 tgacaacgtc gtggcaattt actctcgctt tggcagcctc taaggtctca tccttgatat
    19921 tttgtccgag gagcaacatc tcgggcgtat tgtacatacc cctgtatttc tcctgtccga
    19981 tatatactac atttctcaag cgtgggaaac gctcgctttt caaatacccc cgttgagagg
    20041 tcttcaattc cggcaacatg gtatagacca tgtccacgta acttccatca aacacgccgt
    20101 ctgtgataca catcgtatgg atatcggcgt tctctactag gtattccagc tcgctttgtt
    20161 tatagttcgt attgatcgtg accaatacgg caccgatctt cgcgcctgca tataggaatg
    20221 tcaaccaatc cggtacgttc gtcgcccata cgccgacatg tgtgccatgg gtgataccga
    20281 tcgccaacat acctttcgcc atgtcgtcca cacgcttgtt gaattcgctc caagtgaaac
    20341 gtaagtcacg gtctgaataa acgatatact ccttatccgg tgtattctcg gcccaatgtt
    20401 ccagccattg gccaagggtt ctgttatgta attccataaa acgccggatt taataaggtg
    20461 tatagacaac tcctaggatt cgggccttgt tgtcggctgc cgcatgtaca tgatgcgcca
    20521 cgatagaatc ataatagatg ctatcgcctt cctctaggat ataggtgttc tttccgtaat
    20581 tgatctctac gacgccattc aatacgtaga taaactcctc tccctcatgc gtggacagga
    20641 tgaaatcctc gccttcctcg gagggagcga tctcgatcaa gaagggttcc atatggcggc
    20701 cggacttatc ttgtgagagc gagtggtaat ccatatgctt gtgtccttgt gtcgcgttgt
    20761 tcgtgaaccc gataccatcg gcctcgctgt cctttttgcg gcatacgact gggcctagct
    20821 ccgcttgatc atccaagaat gtacccaaac gtacccctaa tacccgtgct attttgataa
    20881 gaggggccaa agatggaaaa tccaagttac cctcgatacg ttctatctgt tcgataccta
    20941 acccggagcg ttcggctacc tcctcgatag agagttgttt cgattcccgg atatttttaa
    21001 ttttcgcgcc tataattttg ttgtttccca tgtgtatgat ttgttattta tagtcctgta
    21061 atgtttgata atttgatact aaacggcgca aatttacatt aatattttat tatatctagg
    21121 attaagacaa ataaaaaggg caatacccat ttgggattgc cctttttaat attttcgagt
    21181 aagctttttc ttactttctg ataccaagtt ctttgatgat agcgcggtat ctctcgatgt
    21241 cagtcttgat cagatagtcc aataaacgac gacgtttacc taccaacatc ttcaatgatc
    21301 tttccgtagc gtaatctttg tgattcactt tcaagtgctc tgtcaagtga gagatacgga
    21361 atgtgaacaa tgcgatttgg ctctcagcag aacctgtgtt agttgctgat ttgccatact
    21421 tttcaaataa ttcttttttc ttcgctgaat ctaaatacat gattcttttt actttaataa
    21481 attaatacta tgttatctaa gcggtcgcaa aggtagacat tcctttttga tttgcaatag
    21541 attctactat ctttttt
//
