LOCUS       gnlProkkaCHADNLBK_6    16737 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CHADNLBK_6.
ACCESSION   gnlProkkaCHADNLBK_6
VERSION     gnlProkkaCHADNLBK_6
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 01:45:09
            Original ID  :: gnl|Prokka|CHADNLBK_6
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 28428
            Orig. end    :: 45165
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16737
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10267]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..16737
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16737
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3700..6054
                     /locus_tag="ctg6_25"
                     /transl_table=11
                     /translation="MKRLILYIAGLIFLAGCSTTKHLPEGEILYTGQKPMIVLNRSETS
                     VGEIAMEEVEAALATAPNNSLLGSSTIRYPFPFGLWIYNGFQKYEKGFGKWIFNKFAAT
                     PVLMSTVNPDIRQKAAVNLLRDYGYFNGSVSYKTFIDPKDSLKAKLQYTVNMRNPYFID
                     TVYYRGFSERTTRIMELGRRRSLISSGEQFNVADLDGERTRISTLLRNVGCYYFRPDYL
                     TYQADTMIVPNGHVQMRLIPVPGMPKVAEKQFRVGRKSVYLLGKQGQEPNDSMDYKGLT
                     IHYYNKPPVRPNMLYRWLNYQGYRRKRQIQDSAGIARQRSMQSLYSLYRQTRIQERLAS
                     VGIFRYAEMQYIPRDTAFVSDTLDVRVIAALDKPYDAELDFNVTMKSNNQTGPGAAFTV
                     TKNNVFGGGESWNVKLNGSYEWQTGKASSSLMNSYELGISTSLIFPRVVFPRMGDREYD
                     FPATTTFRLYADQMNRAKYYKLLAFGGNVTYDFQPKSTSRHSITPFRLTFNVLRNPTAA
                     FDTLRAENPALYVSLRDQFIPAMEYTYTYDNASVRGKRNPIWWQTTVASAGNLTSAVYR
                     IFGKPFSEEGKKLFGVPFAQFLKLNSEFRYHYRIDKNQMIASRIAGGVIWSYGNATTAP
                     YTEQFYIGGANSVRAFSARSIGPGGYPPETDRKYTYINHVGDIRIEANIEYRFRMIADL
                     HGAVFLDAGNVWLMRKDENRPNGEFTLKNFPKQIALGTGFGLRYDLDFLVFRLDLGIGL
                     HDPYDTGKSGYYNIPKFKDSMALHFAIGYPF"
     CDS             6213..7091
                     /locus_tag="ctg6_26"
                     /transl_table=11
                     /translation="MGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGFGKLVFVIRKDF
                     EQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAVMMGADVIKEPF
                     AVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGTVSRGLCGTDAN
                     NLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDYFAYSAEFFKSF
                     LSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPEDRQSVVDKIQAL
                     VDAGEYPAKLF"
     CDS             complement(7136..8806)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 277.6; E-value:
                     3.6e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg6_27"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFRYTPDDRPVFSRFSCRFPAGSCIAIVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETNHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASQEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(8829..9992)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_28"
                     /sec_met_domain="NTP_transf_5 (E-value: 6.2e-46, bitscore:
                     148.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRYFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             complement(10001..10267)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_29"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.8e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.3e-15, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             complement(10280..10720)
                     /locus_tag="ctg6_30"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             complement(10747..11673)
                     /locus_tag="ctg6_31"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             complement(11920..15477)
                     /locus_tag="ctg6_32"
                     /transl_table=11
                     /translation="MQVACMATAALTAFSCSQEEFENSGWKGNITVNATFEGAGTDTRT
                     TVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSGETAVFSI
                     YPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMAAMIKLTV
                     NKIPAEATTFKIIASNNIAGTCTVDLTAADPILTVASNGSKEITASFTASNDIKSRNFY
                     IPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVDATTPSALST
                     ALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLTFNTAPTTST
                     AAPLTLTDKTNTSVSAPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTLAAVGNKA
                     TYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGDTTIYIIKGTEAS
                     LPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLDLNGYTLT
                     ADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDASMTMESGN
                     ISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIINITDGELI
                     STADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGSTGNWGDGT
                     GGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFSDPSALKY
                     MKANANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETNSCQLLEG
                     SNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINNTTINAGS
                     NANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTELMKLNITSGTFNGDLK
                     VDASVRTENAQSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTKLATGYILNA
                     ANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASATAKDDGYR
                     MVIEARGYGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYGTPNNDTD
                     GRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDGSVYTAAH
                     KVGDGRKEYIVGQTSQENR"
     CDS             complement(15512..15727)
                     /locus_tag="ctg6_33"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             complement(16093..16434)
                     /locus_tag="ctg6_34"
                     /transl_table=11
                     /translation="MESLIMKDCYGIDFRSWHKELRTREKTKQPPCKLPDRASRSLQGV
                     LFKVYQISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVR
                     SDNSPNSYK"
     CDS             complement(16642..16737)
                     /locus_tag="ctg6_35"
                     /transl_table=11
                     /translation="MQSFDDRKQSCSWPLGVINSLCHSRQTKGEE"
ORIGIN
        1 tccatgtatg agcgttccgg tttgagcgtc acctccctga ccggacggtt gtttgccgat
       61 tctaccgtta tccgtatccc ttctttgaag ttgctgacac ctcatagtga gatgaacctt
      121 acggcacaga cttactggga actgataaat atacctacca ccggccgtct gacagcccgt
      181 ttcaatgccc gtatcggcaa acaggatgta ctgctttttg ccggtggctt gccggaagct
      241 ttcaaggaag cctatccatt ccgtccgttg gtgattcatg ccggtacgga aggaaacctg
      301 aagcagatgc agatttcccg ttttacggct gagctgcccg gagccttttc gttgagtggg
      361 ggaggagaat tctggagctt gaccgacagt gtgaaacgca atggaagcat ggacttcgaa
      421 atgcatacgc agaacttgaa cttcctgacc ggactagctg acattgctcc cgatggctcc
      481 atcattgtgc cggacagtat gcaccttgcg gcacgtctcg gtatggaggg ggcgcagtgc
      541 actgccgccc tgaaactgaa ggagaaggaa ggcgccttga atttggacgc cgcctataat
      601 cttgctacgg aagcctacca tgccgacctt gccatcaaca acttgcaggt gcatcacttc
      661 ctgcccaagg actctatcta tactcttacg gcaaagatgt ccgctaaggg gcaaggggtg
      721 gatgtggcat cacgaaaaac tgtggccgct ttgaatgcct ccttggaaaa actacagtat
      781 ggccattggg acatttccgg tgtagatgtg catgccggac tcaagtcatc cgttgctacc
      841 gtccgtcttg ccagcgataa tgtccttctc aagatgcagg gaaatgcgga tatgcgtctt
      901 gaccgcagct atctggatgg cgctttggat ttaaatgtgg aagaggtgaa tctgcataag
      961 ctgggtttgg tgccccgacc gttgaaacac ccgtttgcct ttacaatggg agcggaggca
     1021 cgtcatgatt ctctcaagtt gaggcttgat gccggtgact tgaatctgcg tttccgcgct
     1081 cacagcacgt tgaagaggtt gatggaacag tcggataaat ttgtctctat cctgacaaag
     1141 cagattgatg aacggcgttt ggaccatgcc gctttgcgcc aagtccttcc ttcagcgggc
     1201 atgcatctgg aagccggtaa ccagaatccc gtcagctatt tcctggctgc aaagggtatt
     1261 tcctataatg atttcaaact gagcttcgga tttactccgc aagtcggcat caatggacgt
     1321 acagctgttc acggattgcg catggactcc ttgcagctcg atacgatatt ttttacagtg
     1381 aagcaggata ctgcccgcat gaagttgcaa ggtggtgtca taaacggtcc caagaacccg
     1441 cagtttgtgt tccgtagcac actgacgggt gaagtccgta atgaagatgc ggaactgact
     1501 gtggattatg tgaatggaaa agggcagacc ggtgttctat tcggtattaa tgcccgtccg
     1561 ttgaccgaag gacacggtcg cggtaatggt gtgctgctga accttattcc tgccgagccg
     1621 attatcgctt tccgtaaatt ccactttgcg gacaatagta actggattta tctgcataag
     1681 aatatgcgcg tctatgccaa tattgatatg gacagcgacg atggtctgtg tttccgtatg
     1741 caatccgaca agaatgatac cctttccttg cagaatataa acgtagaact gagccgattg
     1801 cgcctggatg aacttacgga ggtacttcct tatatgcccc ggcttacggg attgttctcc
     1861 gccgaagcaa attatataca gactgccact tccctgcagg tgtccgccga agccaatgta
     1921 gagaaactga cctacgaacg ccaaccggtt ggagacatcg gcctgggggc tacctggttg
     1981 ccgggcgaca agaatacgca ctatctgaat acctatttta catatgataa tgaagaagtg
     2041 atgaccgccg acggtatctt gacgcagaag aacggaaagg ataccctgga agtgtccacc
     2101 cgtttcgagc attttccatt gaagatggcc aatgcattca tccctgacca aacggtggcc
     2161 tttaccggag atattgatgg agggctttat atttatggtt cgctggacaa gcctcagatg
     2221 catggtgata ttgttttgga cagtgtgtct gtctatgcac gccaggcggg agcacgttac
     2281 tggttcgaca accgtccggt acagataaag gacaatcagt tgatatttga taagtttgcc
     2341 atttatacca ccagcaagaa tccgtttacg attgacggta aggttgattt ccggaatatg
     2401 gagcgtccta ctgccaacct caatctgctg gcagagaact atacgttgct ggatgcaccg
     2461 cgtactcgcg aaagtctggt gtatggaaag gtgttcgtcg acttgcatgc cacggtgaag
     2521 gggccgcttg acgggctcac gatgcgtgga aacatgaatt tgctgggcaa taccaacgta
     2581 acctacgtgt tgaccgattc ccctttaacg gtggaagacc gtctcagcgg gctggttacc
     2641 tttacctcgt tcaccgatac gacgtcggta aaagcggatg aggttcctac catgtctttg
     2701 ggaggattgg aaatgtatat gtccgtccat attgacgatg ctgtccgtct tcgtgctgac
     2761 ttgagtcccg accgcagcaa atacatcgaa ctggaaggtg gcggtgattt gaatatgcag
     2821 tatactcccc aaggggatat gagccttacc ggacgctata ccctttcggg tggcgtcatg
     2881 aaatattcgc tgcctatcat cccgttgaag gagttccagt tcaatcccgg cagttatgtg
     2941 gattggcggg ggaatattat gaatcctacg ctgagcctaa aggctacgga acgtatgcgt
     3001 gcttctgtgg ccgatggtga cggggacggt tcgcgcatgg tgaacttcga tgtttccatt
     3061 tccatcaaga acaggcttga cgctcccgat ttgatattcg atatttcggc gcccgaagat
     3121 gccgcagtag agaatgagct gcaggcaatg ggtgcagaag agcgtagcaa gcaggccatt
     3181 gccatgcttg ccacgggtat ttacttgaac agtggtgcca aaggaggagg tttgtcaatg
     3241 ggagctgcct tgaactcagt gcttcagagc cagataaact ccttggcggg aggtataaaa
     3301 ggcgccaata tcagtgtagg tgtggaagac cgtacctctg ctgaaacggg tgacacgcag
     3361 aaagacttca gttttcgtta ttcccagcgt ttcttcaacg accgcgtaca gatagtcatc
     3421 ggtggaaaag tgtccaccgg ggccaatgcc acgaacgatg cggaatcatt cattgacaat
     3481 atatcgctgg aataccgtct tgatgcgtcg ggtactcgat atgtccgtgt attccataat
     3541 aaaaactacg aaagcatact cgacggtgag ataaccgaaa cgggtgtcgg ccttgtgctg
     3601 cgccggaaga tggaccgatt gagtgaactc ttcatcttca ggaagaaaaa gataaaaccg
     3661 gaggctgaaa atagcgatat gaaaaagtag gaatgtgata tgaaacgact gatattatat
     3721 attgcaggat tgatatttct ggcaggttgc tccaccacga agcacttgcc cgagggggag
     3781 atactctata ccggccaaaa gccgatgatt gtattgaacc gcagtgaaac gtctgttggt
     3841 gagattgcta tggaagaggt ggaagccgcc cttgctacgg caccgaacaa ttcgttgctg
     3901 ggaagctcta ctatccgcta tccctttcct ttcggactgt ggatttacaa tggtttccag
     3961 aagtatgaga agggattcgg aaagtggata ttcaataaat ttgccgccac tccggtgctt
     4021 atgtctacgg tgaatcccga tatacgccag aaggcggcgg ttaacttgct gcgcgattat
     4081 ggctatttca acggaagcgt cagctacaag acatttatcg acccgaagga ctcgctgaag
     4141 gcaaagttgc aatatacggt gaacatgcgt aacccctact ttatagatac ggtatattat
     4201 cgtggtttca gcgagcgtac cactcgcatt atggagctgg gacgccgacg ttcccttatc
     4261 agttcgggag aacaattcaa tgtggctgat ttggatgggg agcgtacccg tatcagtacc
     4321 ctgctgcgta atgtgggctg ttattatttc cgtcccgact acctgaccta tcaggccgat
     4381 accatgatag ttcccaatgg gcatgtccag atgcgcttga ttcccgttcc cggtatgcca
     4441 aaggtagccg agaagcagtt ccgtgtgggg cgtaaatccg tctatcttct tggaaagcag
     4501 gggcaggaac ccaatgacag catggattac aaaggcttga ccatacatta ctacaacaaa
     4561 cctccggtac gtcccaacat gctttaccgt tggttgaact atcaaggtta tcggcggaaa
     4621 cgtcagatac aggacagcgc aggtattgcc cgccagcgtt ctatgcagag tttgtatagt
     4681 ttgtaccgtc agacccgtat tcaggagcgt ctggcaagcg tcggtatttt ccgttatgcg
     4741 gagatgcagt atataccgcg tgatacggcg tttgtgtctg atacattgga tgtgagggtc
     4801 attgccgcgc tcgataaacc ctacgatgcg gagttggatt ttaatgtcac catgaagagc
     4861 aataaccaga cgggaccggg tgccgctttt acggtgacga agaacaatgt cttcggtggc
     4921 ggtgaaagct ggaatgtgaa gttgaacggt tcgtacgaat ggcagacggg caaggcaagt
     4981 tcttccttga tgaacagtta tgaactgggt atctccactt cgcttatctt tccgcgcgtg
     5041 gtgtttccta ggatgggcga ccgtgagtat gacttcccgg ctacaacgac tttccgttta
     5101 tatgccgacc agatgaaccg tgccaagtat tataagctgt tggcttttgg cggtaatgtc
     5161 acttatgact tccagcccaa atcgacttcc aggcacagta taactccttt ccggttgaca
     5221 ttcaatgtac tgcgcaatcc tactgccgct ttcgatacgt tgcgtgccga gaatccggca
     5281 ctctacgtta gtttgcgcga ccagttcatt cctgccatgg agtacaccta tacttatgac
     5341 aacgcttccg tgcgcggcaa gcgtaacccc atctggtggc agaccaccgt tgcgtcggcc
     5401 ggtaacctga cttctgccgt ctaccgtatt ttcggcaagc cgttcagtga ggaaggaaag
     5461 aagcttttcg gggtaccttt tgcacagttc ctgaagctga actcggaatt caggtaccat
     5521 taccggatag acaagaatca gatgatagcc tcgcgtattg ccggaggggt gatatggtcg
     5581 tatggcaacg ctacgactgc accttatacg gaacagttct atatcggcgg tgccaacagt
     5641 gtgcgcgcct tttctgcacg cagtataggt ccgggcggct atcctcccga gacggatagg
     5701 aaatatacct atatcaacca cgtgggtgat attcgcatag aagccaatat cgagtatcgc
     5761 ttccgtatga ttgccgactt gcatggagcg gtgtttctgg atgccggcaa tgtatggctg
     5821 atgcgtaagg acgaaaatcg cccgaacggt gagttcacct tgaagaattt cccgaaacag
     5881 attgctttgg gtacgggatt cggcttacgc tatgacctgg acttccttgt tttccgtctg
     5941 gatttgggta tcgggcttca cgacccgtat gataccggaa agtcgggata ttacaatatt
     6001 cctaagttca aggatagtat ggcactgcat tttgccatcg gttatccgtt ctaaatgtac
     6061 gtttttgaac ggatagtggt aaagaatgaa ctaaaactcc cttttgtcag acataaattt
     6121 ttgtacattt gcaaccgtta tcaactatga tacactaacc tttttaaata ataactaata
     6181 tgaaaccaac tttattctta ttggcagccg gtatgggcag ccgttatggt ggcttgaaac
     6241 aattggacgg attgggaccg aatggcgaaa ctatcatgga ttattctatt tacgatgcca
     6301 tcaatgccgg ttttggcaag ctcgttttcg taatccgtaa agattttgaa caggacttcc
     6361 gcgacaagat tatttccaaa tacgaaggcc atattccctg cgaactggta ttccagtcca
     6421 tagatgacct tcctgaaggc ttcacctgcc ccgaaggccg taccaaacct tggggaacca
     6481 accatgctgt aatgatgggt gccgatgtaa taaaggaacc gtttgctgtt atcaattgcg
     6541 acgatttcta cggtcgtgac tccttccagg taatgggcaa attccttgca gcccttcccg
     6601 aaggctccaa aaacgtatat tccatggtag gcttccgcat cggcaatacg ttgagcgaga
     6661 gcggtaccgt atcccgtgga ttgtgtggaa cggatgcgaa caacctgctg acttccgtag
     6721 tggaacgcac caagattcag cgtatggatg gcgaggtgaa gtacatcgac gataacggtg
     6781 aatggactgc cactcccgag acgactccgg tcagcatgaa cttctggggt ttcactcccg
     6841 attattttgc ttacagtgca gagtttttca agagtttctt gagcgacccg aagaatatgg
     6901 agaacctgaa aagcgaattc ttcatcccgc tgatggtaga taagttgatt aacgatggca
     6961 ctgctacctg cgaagtgctt gatacaacca gcaagtggtt cggtgtgact tatcccgaag
     7021 accgtcagag tgtagtcgac aagattcagg ctttggtgga tgcgggcgag tatcctgcga
     7081 agctgttctg agtttgttaa ccaaaggcag atacccgttg gggcttattc tctgattata
     7141 atcggacaat agattcgcat gcctccgcta ctgccggatg gtgggtgacg aagatacatg
     7201 ttttgcctgc gcagtctctg cgcaggtttt ttattaacag ccgttccgtg tcggggtcga
     7261 gggcagaagt ggcttcatct aaaagaagaa tgtttccggg gcgtagcaga gcgcgggcaa
     7321 tggcgatgcg ttgggcttgt ccttcactga gtccaccacc tcgttcgctg agtggggagt
     7381 ctacgccgtc gggaaggtgg aagacgaagt cggcggtggc ggtttgcagg gcttgatata
     7441 tggcttcttg agaagcttgt gggtttccca tcagcaggtt gtcacggata gttccgctga
     7501 aaagggtatt gccttgcggg acatatacga agttcttgcg ggtttgcgga gagacggtat
     7561 gattggtttc aagtggatgt ttggcgggta tcaagagtat ctgtccctct tgtggcgttg
     7621 ccagtgccaa caatagccgg atgagcgttg tctttccttt tcctgtttct ccgactatag
     7681 ctatgcagct accggcgggg aaacggcagg agaagcggct gaataccgga cggtcatcgg
     7741 gagtgtagcg aaaagtcacg tctttcagtt ccagttccgg ggtagaggcg aggaatatgc
     7801 tgtcaccatc cgcttctgcc ggcagtcttt ccaattccaa tagccggtct atggcggtaa
     7861 gggcattgac tacggaaggt atcaggcgtg agaggtcgaa cacgggacgc tggacttttc
     7921 ctaccaattg caaaaaggcg gtcatcgttc cgaaggtgat acagcctgcg ctgaggtgaa
     7981 cggctcccca aagaaaagcc gtgaggtatc cgccggaaaa ggcaagggcc actaacatgt
     8041 gggcagaaag cgagaaacgg gtacgtccca tgacttggct gtggagcatg tcttgcaagt
     8101 catcgagttt gtccagatgc cgttcgcctt gttccaatgt tttaatcact atgcgatgtt
     8161 gcaggctctc ttgtatgacg gactggatgc gaccgtcact gttccgaata tcatgtgtat
     8221 agcgtttcat tcgtcgcata tagaaacggc tgcctgatag aaagacgggc aggatggcaa
     8281 caatcagcca tggcagtgaa gggtctaaaa agtagaagaa tagaaaggct gccagcagtt
     8341 gtatactcgt gacgatgaat gccgggacag aagaggtgag caatgtgacg atggcggtgg
     8401 tgtcttgttc tacccggttc actacgtctc cggtatggaa acgctccaat tcgttccagc
     8461 ggctttgcag taagcgcgag aagaggcggt ggcgaagggc gttgcccgtc tctatctgca
     8521 tacgggtact tatccaagtg tcagcagctc cgcacagtaa ttgggcagtc agcaggacaa
     8581 cggtgagaac ggcgatatgc gtcaggttgt cgtctgttat tccggtagcg gtgtctatca
     8641 cccgtttggt tgcatagata aaggctaggg caaaggccac gcccagaatg ccggtgaggc
     8701 aacttagcag gatacgtccg cgttgttcgg cagatacctc tcgaatatac ctaagttttt
     8761 cacgtctgtc ctttttcact tttttgtcct tctgttgctt tttcattcct tttattttcc
     8821 gggttctttt atttctttgt ccttgctttc ttgtctttta ctccttttga tcggtttatt
     8881 tgtatagcta tcgttccccc tatcagagtc acgggatacc agagtgcttc gtacggtgca
     8941 aattgacgca gttcgttgca gcgtcgggtg gcgcggcaga aggtgtacca ctttcctgcc
     9001 caatatcctt tggggcgtgg cttgatgcgg ttatcatgtt gcccgaagtt accggtagac
     9061 aggatgtctt ccaataattg ttctcctatc tgcttggtgc cttccaaggg gaaaggaagc
     9121 cggttggcgg gcaatcccag tcgggtgacg gcaatgtagc cgaatgcttg tgcggcatgc
     9181 aatagtccga ggtcctgcaa ctggcgaagc agggtggtgg catctatttc tttgtggcga
     9241 ttggcaagca gacaagtcca gtcgcatagc tggcgcaggc cgattccgct gttcaggaaa
     9301 tgtacaaagg catgcaggaa gatataaagt gcattgaagg tggccggagg tatggcgata
     9361 ctgacggcct tcgagtcctc tttcccggtt tcggagaata gggcatagtc tgtttcctgc
     9421 gggtaccatt ttctgataat ctgctgaaag taccggttgg caagcggact gttcagccgg
     9481 aggatgatgc ggtggttctc gatgtgtact cctttcaaac tgtagctagc atgcttgtcg
     9541 gacgcttctc cctcgactat ggcgccttgt tgcagcagga ggcggttggc tatgggttgc
     9601 ccttgttttc ctaaatagat gtcgatgtct ccgcattgcc ggtgcaaggg agtgcggtag
     9661 ttggtgccga tgccttgccc tttcagcagt acgggatgca gcccggcttc ccggtaaagg
     9721 gtattgagtt cgggcagaag ctggttgagg cgtttgttgg cttgttctat ctgtgcagtc
     9781 cgggcagccc atttcagata gaggacgcgt ggagggcgca gttcggccgg cagactgctt
     9841 atgccgtcaa aagtcagtgc aagcagggct tgtgagtttg ccatgcggta cacggtttcc
     9901 cagtcgtccg gcgagaccga ccggaagagt tgtcggtctg ccggagtgcc ccacaggccg
     9961 gagcgtacca atgaaaagaa agcgtgttgc atatccgtcc ttattctatg attccttcgc
    10021 ggtcaaggga gtcgataaac ttctgcgcat cgcgacgggc cgattcgtta tctacatcat
    10081 agcggctggt cagggcttct gtcacgctgt ctgtatcgaa ctctttgttt tctatctctt
    10141 gccaaagcat ggcggaagtt tggttcaggc tgatgacttt gctgaagtcc acgttcgacg
    10201 agccgtcttg catgatgatg tagtcatcgc ctatccggtg caggataaat ccttgtttga
    10261 ttttcatggt tattttgttt tatattcttc tgaacagggc gagcagccag cggcgagcgg
    10321 ggtttagctt catccaccag taggagtaga gcttccagac tttgccgtcg gcggtgtacc
    10381 gtttgtcttt tcgcatggct tcggtcatga cgcccattac ccgtccgatg tcggtttctt
    10441 cggtctgggc gaggttgccg tcgccttgca ggatgagtat gtctccgttc cgacggatga
    10501 tgcggtgaaa gacgatgcgt tccgtcaggt cgcgtgccag tacggtgacg cccggttgca
    10561 gctgttctgt ggtgaaatcg cccagtgtca cccggtcacg gcggtccact aagaaaggat
    10621 tcatgctgtt gccccgcacg gtgatggtta ctgtatgtcc ctctttgatg agacgcgcca
    10681 cttcgggaag caatatctcg ttgggaatgc ttttcttcat cggctgttca gttcatcatt
    10741 cataacttat ccttctaccg tctttctgca aagttccgtc gcttcacggt cgggtaggca
    10801 tttcagatga tagacgggtg ccagcgtggc aagttccgtc acagtggcga caatggcgtt
    10861 atagatttcc ttgttctgct ttaggcaaga gcaggagggg aggagggtgg cgaaagcatg
    10921 tgctgctctc tcttgctcta tttcattctg cggtgcttgt tccaagcgga cgaaggcgcc
    10981 tacggtcatg gattctttcc gatagcaagg tgtctttccg ctccacggag aaccgaaaac
    11041 agtggcttgc ttgccgaggc tgtccacatg tactatcgga ttgtcatcgt tcagtagatg
    11101 gcagtccgag aactgttgca gccagagccc ggtgtgcgta cttttgcccg tgccgctttt
    11161 ccctaagaag aggtagcctt tgcctgtttc agtagcgaca accgaggcat gcatcagcag
    11221 tgtatggtgg cgggcggcat tgaaggcata gagcatcatc aagaagttgt tcagtacgaa
    11281 gttcgtttcg ttttccggag ccggtgtttc tgtcctgcag gccggtaggt ggatgaagca
    11341 ttgcctgaag ttatcgttgc actccatcca atagtttttc ccgcttttcc gtggggtgat
    11401 ggatacaagg tgtgagctgt ggggcaaagg gcgaatgatg caatcggcat cttcccagtt
    11461 gaaacatata tcatcgggag ttttcgctat ggttcgtttt gtcgttgttt cgtcatcgtc
    11521 tatctctgtt tcaaagatta ctttttgcgt cgtgtctatt gtcgtgatga acggaatcag
    11581 tgaaggcagc gccttgaata tattgaagtc ggaaggtttc accatgcgaa aggtgtgcgg
    11641 tcctacttga taatccaata tctgtattct catatgtttt gattgttagt tgttattcat
    11701 gatactttgg gctactcaga aaaataatga atgtttgtgt gaatgaggaa gatttgagag
    11761 atttttcaac tgtcttgttg tcattcttta gacgcggagg acgcagatct ataaaagaaa
    11821 atccgctgtc cgccgcatct aaaagatagt aataaggcga ttccgatatc tcttcgtttg
    11881 gtttgcgagg atatattgct tcctttctta gaatttggct tatcggttct cctgacttgt
    11941 ttggccaaca atatattctt tcctcccatc accgactttg tgggctgctg tatatacact
    12001 gccgtcacgg gtaacctcgt agcctgttac caaataggac tcattgtcgt ccatattcgg
    12061 atttgccggg ttgaaattga tgaacgttcc accggacacc tggatgctgg cagtgttctt
    12121 gtctgtattc tttaagttca gtacccagta tctgccatcc gtgtcgttgt tgggtgtacc
    12181 atatttgccg gattcaaatg ttcctccata gatattgatt ttcccattct ctcttgcata
    12241 aatcaggtct atctgggtgt tcagtttctg ggtgttatag taagaaccac catgaatatt
    12301 tactgtcccg tatcctcggg cttcaattac catgcgataa ccatcgtctt tcgctgtagc
    12361 agatgcatcg cacttcacat tgccgttgcc tgaaatgttt agtgttccgt tctgtacagt
    12421 aaagatttgt gtgaaaggag tggcatcagc tgtttctgag gaattgatga tgtcgtggcc
    12481 attcaggttt aagtttgccg ttgcgtttgc agcattcaat atgtagcctg tggcaagctt
    12541 cgtcttggcg atgttgatat ttgagagaag ttttatatcc acagttgcgt tggttgccat
    12601 gtacttcagt acgcttgggt cggagaatgt acctccggaa acagagatga tactttgggc
    12661 attttcggtt ctcacggatg catctacctt taagtcaccg ttgaaagtac cgcttgtgat
    12721 attcagcttc ataagttcgg tatttcctgc actcttggaa atttccactt ttccattgat
    12781 gacgctcgta ccgcttaccg taaccgtgac tccagcagtg tactttgcat agccgcatac
    12841 gtcgaatgca aattgattcg cattgcttcc tgcgttgata gtggtattgt tgatgcttat
    12901 gttgccacaa ttgttgctta ctacgtattg ggcatttgtg tcttctactg tcatattatc
    12961 taatgtcagg ttgcagtagt tctgaatcat gattttgttg ttgtcactct tcagcgttcc
    13021 gttcttgaaa gtaacgtttg aaccttcgag taattgacag ctgttcgttt cggtgccggt
    13081 ggaacctacg gtcgggtcag caagtgtaag aatcttgccg cctaagtcca tcgtcaaggt
    13141 ttgtccgctt gtggtcttga atcccgggca ggtcttgtcg gcggtcaact ttatgttcac
    13201 atttgcattt gccttcatgt acttcagcgc gcttgggtcg gagaatgtac cgccggtaac
    13261 gttgatgacc ggtgtataag tggtgccttc tgtgatgagt gactttgctt cggcaatcag
    13321 tgtaccgcct ttgatgttta ctgtggcaat gccatatgct ccacttacgt tgatggcggc
    13381 gcagtccagt cctccggtac cgtcgcccca gttgccggtg ctacctgtgc ctttactggt
    13441 aatcaaggct gtaccttcca cattcagagt gcctcgttgg atgcatacac ctcctgcggc
    13501 accataaacc ttgccgccac tgatggtcgt tgtgccggat tggggcagat agactgcata
    13561 gtcagcagta gaaatgagtt ctccgtctgt gatgttgatg atggagttct gcgtcttgta
    13621 attgccgttg cctgccactg caaaccatcc ggcttctatc ttgccgcctg tcatggtgaa
    13681 gtctccaccg tccgtcactc cgacgccata ttggccgtta ctgtccggag tctctctgac
    13741 tgcactgatg ttgccgcttt ccatggtcat ggaggcatct tcaccggcta tttcaatcag
    13801 actgccatta taagaagccg ctgtataatc ctggctggca actatcttgc ctttcttctc
    13861 ggtagagctg tccttcagtg tcatcttgcc caagacgatg attttgcctg ttgcgctgtt
    13921 gtcggcagtc agtgtatatc cgttcaagtc aagaaccacg gactttccgg cgggtacact
    13981 gacgctttgc cctgtgatgt cggcatcggc ggacaattta aaatcttcgc cgttggcgaa
    14041 agcggtcttt aggactgcca cgtcggattg aactacaaat ttgctgtcga ttgttgccgg
    14101 aagtgatgct tcagttcctt ttattatata gattgtggta tcgccggcat cgtgtaccaa
    14161 ttgttctacc tttccatata tcttcaagtt accgcctttt acagtcagct tctttacggt
    14221 gacgcctgca ttgataatca atgtctgctg ggcggtagtg gcagtcactt cattgtaagt
    14281 ggctttattg cctactgctg ccaatgtaac ggtggtgctt ggcatggtga tggctacaga
    14341 aggagcttct tgctctgctg tggtttccgg tacagccaag gatacactgt tggtggcagt
    14401 ggcggcggga gcacttacgc tggtattggt cttgtcggtc agcgtcaacg gagcggcagt
    14461 actggtcgtt ggggctgtat tgaacgtcag gttgatgtcc gagttctgta aaaccgggat
    14521 ggcgatgccg tcgttgctgc cagaagtggt attgaagctg ccgctgactg caatgtcggt
    14581 tacggttgct gctgtcggtg cttcttgtgg gagatttttt gaatcagcta aagctgtact
    14641 aagcgcactg ggggttgtag catctacaac aacgcaatcc aaaggaggta ctaccaatat
    14701 gtctcttctc cctaagattt tgtcattaag cgtcttggta aaatatacct tgtcgcttcc
    14761 attcgtcagt tgggcagtga tggaactata agtacctgtg ggcaaaggaa tgtagaagtt
    14821 gcgcgatttt atatcgtttg aagcagtgaa ggaggcagtg atttccttgc ttccattgct
    14881 tgctaccgtc agtatcgggt ctgctgcggt taagtctacc gtacaagtac ctgcaatgtt
    14941 attggaggca ataatcttga aagtagtggc ctctgccgga atcttgttga cggtcagttt
    15001 tatcatggct gccatgtgct tgaaggacag agcgctcaga ttgtcgggat ttgtcacctt
    15061 ggcatacatc gggccattgc tgctgccgtt ataatttgta agcgtggcag gtagagtcat
    15121 ggtcaatgta ttgccgctta cgctcatgtt ttgttggtaa ggatagatgg agaatacagc
    15181 cgtttctccg cttggcttgc tgccgttgaa agtggcggaa gtttgaccag caccgcttgc
    15241 atattctaat tttgtattgc tataattact ttctgcatta ctacagaaca accctagggc
    15301 atcggtatct tgccatagaa tcttgtattc atcgtttacg gtagtacggg tgtcggtacc
    15361 tgcgccttca aacgttgcgt taacggtgat gtttcctttc cacccgctgt tttcaaattc
    15421 ctcttggctg caactgaatg cggtcaaggc agcagttgcc atgcaggcaa cttgcataag
    15481 gtttcttaat ttcatcataa tgaagtcccc cttagttttc tacggttaag atgtcattga
    15541 ttaggtcttc caagtcgctg ctggatgccg aattgtagct atgggtagag gtgctgcccg
    15601 aataggagcg cgtaatggga tggtaaggtt cgccgcttgt tgcaatgact ccttcattct
    15661 ccattttgat aacttcgata gacggagtga tgtatgcttc tctaccgtct ggtgtgttct
    15721 gtttcatata cacaaattat ttaaaggtta aacaataaaa aaaacgtgag taactatgtt
    15781 tgtatatcct ttattcaggc cttcgcattg ccctttccct ggatatacaa cagtcactca
    15841 cgtcgtttgt gtatatacta tcccccctga tgggagaaaa ccatataaac atagacgtga
    15901 gcatccttgt tgttatcttc agggaaattt tcaaagttgc gaagtttgaa taaagaagat
    15961 aatttcaata atgctcttac taatatgtaa ataaacccac tacgctatag cggatttgtg
    16021 acaaagataa ttgttttttg tttaagtgta tctatgtttc tctatttttt ttgggaaagg
    16081 ctcacgtctc tttcatttat aggagttagg agagttatca cttctaactc ccgataactc
    16141 cttcaaatat ttagtaactg tctgcattgt ctttgaggat gtttttctga ggagcatagc
    16201 ggctatgtgg cgaataaaga ggggaagaca gaccgaaaag aagctgaata aaatcttttt
    16261 aagcaaaatt aaaacagaga tttgatatac tttaaacaga acaccctgca aactccggct
    16321 tgctctgtcc ggcagtttgc agggtggctg cttggttttc tcgcgtgtac gtagctcctt
    16381 atgccacgaa cggaagtcga tgccatagca atctttcata ataagacttt ccatattttt
    16441 gcaaatgtcc gtactgcctt tggctgnnnn nnnnnnttct acattccaat atcttaccct
    16501 tataaatgca ttattgaagt ttcgtaaata tacctactga taaatgggaa tttatcgcac
    16561 agagcgcgaa gcctgctctc ataacctatg gagagcacga gtgaaagctt gtggattttt
    16621 atctaaaaca taggtattcc tttactcttc tccctttgtt tgtctgctgt ggcataggga
    16681 atttatgacg cctaacggcc atgaacaact ctgcttacgg tcgtcaaacg attgctt
//
