LOCUS       c00024_gnlPro..        13128 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CHADNLBK_24.
ACCESSION   c00024_gnlPro..
VERSION     c00024_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 14:50:24
            Original ID  :: gnl|Prokka|CHADNLBK_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13128
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13128
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[77:3128](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      78..3128
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13128
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13128
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             78..3128
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_1"
                     /sec_met_domain="PFOR_II (E-value: 3.1e-19, bitscore: 59.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.9e-18, bitscore: 57.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1e-31, bitscore: 100.8,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-12, bitscore:
                     37.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.3e-12, bitscore: 39.1,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 7.4e-08, bitscore: 22.6,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-05, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4.4e-26, bitscore: 81.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFFDGFRTSHEIQKIEMLENEDLAPLIDQEALAEFRARALNPMN
                     PVARGMAENPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAER
                     VIIAMGSVTEAAREAIDHLVANGEKVGLVAVHLYRPFSAKHFLAAVPKTAKKIAVLDRT
                     KEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILAVYKNLAMPMPKNH
                     FTIGIVDDVTFTSLPQEEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHC
                     QAYFSYDSKKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNG
                     SFLLNTIWEGEELAKNLPNKVKKYFAQNNITVYYINATQIAQEIGLGNRTNTILQSAFF
                     RITGVIPVDLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLTVDPAWANLADD
                     AKAENNDPAFINEVVRPINAQDGDLLPVSAFKGIEDGTWEQGTAKYEKRGVAAFVPEWN
                     AENCIQCNKCAYVCPHASIRPFVLDAEEQKGANFTQLKAVGKAFDGMTFRIQVDVLDCL
                     GCGNCADVCPGNPKKGGKALTMKHLESQLPEAANWTYCAENVKSKQHLVDIKANVKNSQ
                     FATPLFEFSGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTKNEKG
                     HGPAWANSLFEDFCEFGLGMELANEKMRARIVKAMEDAIAAEGTPAEYKEVFQAWIENM
                     YDADKSKELAEKIIPMVEAAKDKCDSCKTIASLSQYLVKRSQWIIGGDGASYDIGYGGL
                     DHVIASGKDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYG
                     YVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQAEEEKAVK
                     CGYWHLWRYNPALEAEGKNPFTLDSKEPDWSGFQDFLKGEVRYASVMKQYPQEADELFK
                     AAEENAKWRYNSYKRLSKENWGAEVTE"
     CDS             3220..3588
                     /locus_tag="ctg24_2"
                     /transl_table=11
                     /translation="MIGFIIWVIGVVLCVKAVLEIMKWPVDGVKKLLVAIILLLTSWIG
                     ICVYYFWGXXXXXXXXXLNRSKNKHVYRVGIARQRFLPDLFSGVKRRIQSVSLASSFQE
                     PGRTLPKLFLIAFREIGR"
     CDS             complement(3511..5754)
                     /locus_tag="ctg24_3"
                     /transl_table=11
                     /translation="VKAISAYPGIRLLAVEDGAWLQLKAEEKMDILLDRFPHIDLVYAQ
                     NDRMAAGAYAAVASKGREKEMRFIGIDALPGKDYGVEKVLAGELDATFIYPTGGDRVMQ
                     IAMDILNKRDFPRETILGTSVVNRDNALIMKMQTAHIGTLDGKIETLNGKINQYLVRYA
                     TQQVVLYGSLSALLLLVGLLVAVYLSLRAKNRLNRELSMQKKKLEEQKTQLIQQKEQLE
                     VQKSQLEQLSHELEEATHAKLVFFTNISHDFRTPLTLIADPIEQLLANRTIDGQPRQLL
                     ELMKKNVHILLRLVNQILDFRKVENGRMELHLEPFDLLDSFRGWNDSFRMALLKKHIAF
                     SFEASPDADFRMMADAEKMERIYFNLFSNAVKYTPENGKIALRLLKAEQNYTLSVFNSG
                     SYISTTDVEAIFERFYQVNGHQAGTGIGLALVRAFVEMHGGNITARSDEKGTTFTVTFP
                     QQDVSQYRPTIVTLPVEGEEVSSTLIDMEVKAGEEVVEADCPTVLVIDDNSDIRSYVKS
                     LLSNEFRVLDAADGSEGIRLAMRYVPDVIVSDVMMPGMDGVECCRRLKGELQTCHIPVI
                     LLTACSLDEQRIQGYDGGADSYISKPFNSQLLLSRVRNLIANRRQLRQFFGDNQTIEKE
                     TISDLDKDFVSRFKSLVGERMKDAELNVEDLGRNMGMSRVQLYRKLKSLTNYSPNELLR
                     QMRLKKAASLLASSDMTVAEIAYEVGFSSPSYFTKCYKEQFGESPTGFLKRRG"
     CDS             5827..6246
                     /locus_tag="ctg24_4"
                     /transl_table=11
                     /translation="MQHIGHILSHSFPYLVVVCTDVGRVFVRKDFTVHYNHRNAPVVCL
                     LHNRSYRSGFIRGHNQQIHPFGYQLTNVFCLTVIIVDGSTDVHLHILVEMGFTEYLTVH
                     LAPPFILATLGNADTETCLAPGAGNRHSPKHEQKE"
     CDS             complement(6342..7229)
                     /locus_tag="ctg24_5"
                     /transl_table=11
                     /translation="MNKIIVGMGEALWDCLPEGKKIGGAPANFAYHASQFGFDSRVVSA
                     VGADADGDEILDVFARKGLRTQIERVPYPTGTVQVTLDAVGVPCYEIKEGVAWDNIPFT
                     DELKRLALNTRAVCFGSLAQRSETSRITINRFLDTMPDAEGQLKIFDINLRQGFYTKEI
                     LCESMRRCNILKINDEELVTISRIFGYPGIDLQDKCWILLAKYNLKMLILTCGTNGSYV
                     FTPGVVSFQETPKVPVADTVGAGDSFTAAFTAAILSGKQVPDAHKLAVEVSAYVCTQSG
                     AMPELPVALKERLA"
     CDS             complement(7467..8633)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 99.3; E-value: 7.1e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg24_6"
                     /sec_met_domain="MFS_1 (E-value: 2.4e-31, bitscore: 99.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTKNSSLAKLFPVMLCFFAMGFVDLVGIASNYVKADLNLTDSQ
                     ANIFPSLVFFWFLIFSVPTGMLMNRIGRKKTVLLSLVITFASLLLPVFGDGYVLMLLSF
                     SLLGIGNALMQTSLNPLLSNIVSGERLASSLTFGQFVKAIASFLAPYIAMWGATQAIPS
                     LGMGWRVLFPVYMVIAVIAILWLSGTSIREEKEEGRPSTFGECLALLGKPFIFLCFLGI
                     MCHVGIDVGTNTTAPKILMERLGMTLADAGFATSLYFIFRTAGCFLGAFILQKMAPRTF
                     FGISVLCMLAAMVGLFVFHEKTMIYICIALIGFGNSNIFPVIFSQALFAMPQKKNEVSG
                     LMIMGLFGGTVFPIAMGLASDAVGQSGAVAVMTVGVVYLFFYMLRMKR"
     CDS             complement(8652..10253)
                     /locus_tag="ctg24_7"
                     /transl_table=11
                     /translation="MIADNDVVRSMNVRLAVNKVDYFVPVDLTGFDNKHLSFNFQLIPD
                     SALCWEEMKLSDEFDVSNREKYRPVYHFSPAYGWMNDPNGMFYKDGVYHLFYQHNPYGS
                     MWGNMHWGHATSTDLVTWEHHGDAISPDALGTIFSGSCVVDKDNTAGFGAGAVIAFYTS
                     ASDRQVQSMAYSLDNGKTFKKYARNPILTSTQRDFRDPKVIWHEDTKKWIMVLAVGQEM
                     EIYSSADLKNWTLESKFGEGQGAHGGVWECPDLLELPVEGTELKKWVLVCNLNPGGPFG
                     GSATQYFVGTFDGKRFVNESPAVTKWMDWGKDHYATVTWSNAPAGRAIALAWMSNWQYA
                     NDVPTRQYRSANSVPRDLSLYTSEGETYVKVTPSPELLKLRDKGSKKRAFKVDRTYNLD
                     KLLNDNSGTYEIEMTIKNKDADVIGFQLFNSKGEEVEMYYNLAEKTFTMDRTKSGEVTF
                     SKDFPAVTVAPVEGGNEMKLRLFVDKSSIEAFGNDGRFAMTNLVFPSEPYNRISFYAKG
                     GSCNVTSFTVYKLGLK"
     CDS             complement(10603..12087)
                     /locus_tag="ctg24_8"
                     /transl_table=11
                     /translation="MKIQKMKIPTILGALLVAGTLSAGAQMNSDSLYKEPYRPQYHFSP
                     EKGWIGDPSGFMYYQGKYHMYWWGKVESTDLVHYQQITPYAMTGADDNISYFTGSAVVD
                     KNNTAGFGKGAYVAAYTVFEKDSKKQAQGISFSHDGKTFHYYEGNPVLDLWSTEFRDPT
                     VFWHEPTQKWVMVVAKALEKKIKFYTSPDLKSWTWTSDFGPAGDSEKSWECPDLFQLPV
                     DGDSDKKRWVMVVSVNWAQEQYFIGDFDGTSFKLMENHPAEPLYVDKGLDFYASRTFQD
                     FDGTLDSKISMGWVATWDYAPVAPSKYGKGFWSIPRNLELKTYKEGVRLVQKPVEQLQT
                     LRYKPASVKRALSVGTQRLPGFVPDENVYELDASFSTDVSNTFGLNLCVGEGRKVVVSY
                     DTDSHNLVIDRTHCSDVQIPKFSRMAYTRVEPVDNKIHLHIFVDKSSIEIFANDGKDVF
                     TLLTYPGEAQTGIELFAQKKGTKMELDAWMLKSIWR"
     CDS             12330..12599
                     /locus_tag="ctg24_9"
                     /transl_table=11
                     /translation="VCTQGRMRLVHNKFLLLHIIINQAIFAIIRILTQCKSKPFCVTGI
                     KSRLDFKLMFPSAHNVRFRSSQCLSGINRRLFTQLFHHGMGCLA"
ORIGIN
        1 ccgaaggttc tgtacaagaa gttatggact tggcaggtgt tgcccaccta gccaccatca
       61 aggcccgtgt tccgtttatg aacttcttcg acggcttccg tacttctcac gaaatccaga
      121 agattgaaat gttggagaac gaagacctcg ctccgcttat cgaccaggaa gctttggctg
      181 aattccgcgc acgtgcattg aacccgatga acccggttgc ccgtggtatg gccgaaaatc
      241 ctgaccactt cttccaacac cgtgaatctt gcaacaacta ctatgaagca gttccggcta
      301 tcgttgagga atacatgaac gagatttcca aaatcacagg ccgcaagtat ggtttgttcg
      361 attactacgg tgcagaagat gcagaacgcg ttatcatcgc catgggttct gtaacggaag
      421 ctgcccgcga agctatcgac cacctcgttg ccaatggcga aaaggttggt ttggttgccg
      481 ttcacttgta tcgtccgttc tctgccaagc acttccttgc cgccgttccc aagactgcca
      541 agaagattgc cgtactggac cgtacgaaag aaccgggtgc taacggcgaa ccgttgtacc
      601 tcgacgtaaa agactgcttc tacggtgcag agaatgctcc ggttatcgta ggcggccgtt
      661 acggtttggg atccaaggac actactcccg cgcaaatcct cgccgtttac aagaacctgg
      721 ctatgccgat gccgaagaac cacttcacta tcggtatcgt agacgacgtt accttcactt
      781 ctctgcccca ggaagaagaa atcgcattgg gcggcgaagg catgttcgaa gccaaattct
      841 acggtttggg cgctgacggt acagtaggtg ccaacaagaa ctctgtgaag attatcggtg
      901 acaataccga caagcactgc caggcttatt tctcttacga ctccaagaaa tcaggcggtt
      961 tcacctgctc gcacctgcgt ttcggtgata ctcctatccg ctctacatac ctggtaaaca
     1021 cgcctaactt cgtggcttgc cacgttcaag cttacctgca catgtacgac gtaacccgcg
     1081 gcttgcgtaa gaacggctct ttcttgctga acaccatctg ggaaggcgaa gagcttgcca
     1141 agaacctgcc caacaaggtg aagaagtact ttgcacagaa caatatcact gtttactata
     1201 tcaacgctac tcagattgca caagaaatcg gtttgggcaa ccgtaccaac accatcctgc
     1261 aatccgcatt cttccgtatc accggcgtta ttccggttga cctggctgta gaacagatga
     1321 agaaattcat cgttaagtct tacggcaaga agggtgaaga cgttgtcaac aagaactacg
     1381 cagcagttga ccgtggcggc gaatacaagc aactgaccgt tgacccggct tgggccaatc
     1441 tggcagacga cgccaaggct gaaaacaacg atcctgcatt catcaacgaa gtggttcgtc
     1501 ctatcaacgc acaagacggt gacttattgc cggtatccgc tttcaagggt attgaagacg
     1561 gtacttggga acaaggcact gccaaatatg agaaacgtgg tgtagccgca ttcgttcccg
     1621 aatggaacgc tgagaactgt atccagtgta acaagtgtgc ttacgtttgt cctcacgctt
     1681 ccatccgtcc gttcgtactc gatgctgaag agcagaaggg tgccaacttc actcaactga
     1741 aggctgtagg taaagcattc gacggcatga cattccgtat tcaggtagac gttctcgact
     1801 gtctgggttg cggcaactgt gccgatgtct gtccgggcaa cccgaagaag ggtggcaagg
     1861 ctctgactat gaagcacctc gaaagccaat tgccggaagc tgccaactgg acttactgtg
     1921 ctgaaaacgt gaagagcaaa caacacttgg ttgacatcaa ggccaacgtg aagaactctc
     1981 agttcgccac tccgttgttc gagttctcag gtgcttgctc cggttgtggt gaaactccgt
     2041 atgtgaagct gatttcccag ttgttcggtg accgcgaaat ggtagccaac gcaacaggat
     2101 gttcttccat ctactccggt tcagtacctt ctactcctta taccaagaac gaaaaaggtc
     2161 acggtcctgc ttgggcaaac tcattgttcg aggacttctg cgaattcggt ctgggtatgg
     2221 agcttgccaa cgaaaagatg cgcgcacgta tcgtgaaggc tatggaagat gccatcgcag
     2281 cagaaggaac tccggccgaa tacaaagaag tattccaggc ttggattgaa aacatgtacg
     2341 atgcagacaa gagcaaggaa ctggctgaaa agattattcc gatggtagaa gctgccaaag
     2401 acaagtgcga cagctgcaag actatcgcca gtctgtctca atacctggta aaacgcagcc
     2461 agtggattat cggtggcgac ggtgcctctt acgacatcgg ttacggtggt ctcgaccatg
     2521 taatcgcaag cggtaaggat gtcaacatcc tcgtactgga tactgaggtt tactccaaca
     2581 caggcggtca gtcttccaag gctaccccgg taggcgctat cgccaagttt gccgctgccg
     2641 gcaagcgcgt acgcaagaaa gacctcggtc tgatggctac tacttacggt tatgtatacg
     2701 ttgctcaaat cgccatgggt gccgaccagg ctcaaaccct gaaggctatc cgtgaggcag
     2761 aagcatatcc cggcccgtca ctcatcatcg cttacgctcc gtgtatcaac cacggtctga
     2821 aggcaggtat gggcaagagc caggcagagg aagaaaaggc tgtcaagtgt ggttactggc
     2881 acttgtggcg ctacaacccg gctttggaag ccgaaggcaa gaatccgttc acgctggata
     2941 gcaaggaacc ggattggagc ggattccaag acttcttgaa aggcgaagtt cgttacgcat
     3001 ccgtaatgaa acaatatccg caggaagccg acgagctgtt caaggcagct gaagaaaacg
     3061 ctaaatggcg ttacaacagc tacaagcgtc tttccaaaga gaattggggc gctgaagtta
     3121 cagagtaatt ccgattacta aataaagaat agaggctgct cctgaataag gcgcagtctc
     3181 tatttgtttt ttaatcaaca atactaaata tcacaggtta tgattggatt tatcatttgg
     3241 gttatcggcg tggttctgtg tgtcaaagcc gtacttgaaa tcatgaagtg gccggtagac
     3301 ggcgtgaaga aactattagt tgcgattatc ctcctgctta ccagctggat cggaatctgc
     3361 gtctactact tctggggaag nnnnnnnnnn nnnnnnnnnn nnnntctgaa cagaagtaaa
     3421 aacaaacatg tgtatcgggt gggaatcgca cgacagcgtt tcctgcccga tttattttcg
     3481 ggagtcaaac ggagaataca atccgtttca ttagcctctt cttttcagga acccggtagg
     3541 actctcccca aactgttcct tatagcattt cgtgaaatag gaaggtgacg aaaagcccac
     3601 ttcataagca atctccgcta ccgtcatgtc agaggaagca agcagtgagg cagccttttt
     3661 caacctcatc tggcgcagca gctcattcgg cgaatagttg gtcagcgatt tcagcttacg
     3721 gtaaagctgc acacggctca tacccatatt ccgtcccaag tcctccacat tgagttccgc
     3781 atctttcatc ctctccccga caagcgattt gaagcgggag acgaagtcct tatccaagtc
     3841 actgatggtt tccttctcaa tagtctggtt atctccgaaa aactgcctca actgacgacg
     3901 gtttgcaatg agattgcgga cacgcgacaa gagcaactgc gaattgaacg gcttggaaat
     3961 ataagaatcg gcaccgccat catagccttg gatacgctgc tcgtccagcg agcaggccgt
     4021 cagcagaatc accgggatat ggcatgtctg caactctccc ttcaagcggc ggcaacattc
     4081 cacaccatcc ataccaggca tcattacatc cgagacaatc acatccggca catacctcat
     4141 ggccagccgg ataccctctg acccgtccgc tgcatccagt acgcggaatt cgttcgacaa
     4201 cagcgacttc acatagctgc gtatatccga attatcgtca attaccagca cagtaggaca
     4261 atcggcctca accacctctt cgcctgcctt cacttccata tctatcaggg tagacgacac
     4321 ttcctcccct tcgacaggca acgtcactat agtggggcga tactgcgaaa catcctgctg
     4381 tggaaaagta acggtaaagg tagtaccttt ctcatcgctg cgtgccgtga tgttgccgcc
     4441 atgcatctcc acaaaggcac gtaccagcgc cagtccgata ccggtaccgg cctgatgccc
     4501 gtttacttga tagaaacgct cgaagatggc ttccacatcg gttgtagaaa tgtaactgcc
     4561 ggaattgaag acggacagag tatagttctg ttccgccttt aacaagcgta gggcgatttt
     4621 cccgttctcc ggcgtatact tcacggcatt ggagaagaga ttgaagtaaa tgcgctccat
     4681 cttctccgca tccgccatca tccggaagtc cgcatcggga gatgcctcaa agctgaaagc
     4741 aatatgtttc ttcagcaacg ccatgcggaa agaatcgttc cagccccgga agctgtcgag
     4801 taaatcaaaa ggttcgagat gaagctccat gcgcccgttc tccaccttcc ggaaatcaag
     4861 tatctggtta accaggcgaa gcaggatatg cacattcttt ttcatcagtt cgaggagctg
     4921 gcgcggctgt ccgtcgatag tgcggtttgc aagaagctgc tctataggat cggctatcag
     4981 cgtcagcgga gtacggaaat cgtgcgaaat attcgtgaag aacaccaact tggcatgcgt
     5041 agcctcctcc aattcatgag aaagctgttc caactgcgac ttctgcactt ccagctgttc
     5101 cttctgctgt atcaactgtg ttttctgttc ctccagtttc tttttctgca tggacagctc
     5161 acggttcaac cgattcttgg cacgcaagga gaggtagaca gccaccaaca agccgaccag
     5221 caacaacaag gcggacagac tgccgtacaa gacaacctgc tgtgtggcat agcggaccaa
     5281 atactggttt atctttccgt tcagggtttc tatctttcca tccagggtgc cgatatgagc
     5341 ggtctgcatc ttcatgatga gagcattgtc gcgattgacg acggaagtac ccaggatagt
     5401 ttcacgggga aaatcacgct tgttcaggat atccatggca atctgcatca cacggtcgcc
     5461 accggtagga tatataaacg tggcatccag ttcgccggca agcactttct ccactccgta
     5521 gtctttgccg ggcagggcgt ctatgccgat gaaccgcatt tctttctccc gtcccttgct
     5581 agcaacggca gcataggccc ctgccgccat gcggtcattc tgtgcataca ccaggtcgat
     5641 atgagggaaa cggtctagca ggatatccat tttttcttcg gccttaagtt gcagccaggc
     5701 accgtcttca acggccagca accggatacc gggataagcg gatatagcct tcacaaatcc
     5761 ttgatgacgg tctacggcag gtgtggagcc caccaaacct gagatttcca ccacatctcc
     5821 ctgcccatgc agcacattgg ccacatactc tcccacagct ttccctatct cgtagttgtc
     5881 tgcaccgacg taggccgtgt atttgtccga aaggatttta cggtccacta caatcaccgg
     5941 aatgccccgg ttgtatgcct cctccacaac cggagttatc ggagtggctt cattaggggc
     6001 cacaatcagc agatccaccc cttcggctat cagctcacga atgtcttttg cctgacggtc
     6061 attatcgtcg acggcagtac ggatgtccac ctccacatcc tcgtagaaat gggcttcacg
     6121 gagtatctca ctgttcatct ggcgccgcca ttcatcctcg ctacattggg aaacgccgat
     6181 acggaaacgt gcctcgcgcc gggagcaggc aaccgccact ccccaaagca cgagcaaaaa
     6241 gaataaaatc cgaaggttat gctgtctcat cttcactttc ctctgattta agattgcaga
     6301 tgagcaaaga taacgaaaaa tgtgaaaaga ataagaaaaa tctatgccag cctttctttc
     6361 aaggccaccg gcaattccgg catggcaccg ctctgggtac atacataggc agagacttcc
     6421 accgccagtt tatgggcatc gggcacctgc ttcccgctga gaatggcagc ggtgaaggct
     6481 gccgtgaacg agtcaccggc tccaacggtg tccgccaccg gtaccttggg cgtctcctgg
     6541 aaggaaacca ctcccggagt gaacacatag ctgccgttcg ttccacaagt caagataagc
     6601 atcttcaggt tatacttggc cagcagaatc cagcatttgt cctgcaagtc gatgcccggg
     6661 tagccgaaaa tacgactgat ggtcaccagc tcctcatcgt ttatcttgag gatgttgcag
     6721 cggcgcatgg attcgcagag tatctctttg gtatagaacc cttggcggag attgatgtcg
     6781 aatatcttca gttgcccctc cgcatcgggc atcgtgtcga gaaaacggtt gatggtgatg
     6841 cggcttgttt cactgcgttg cgccaaagag ccgaaacata cggcacgcgt gttcagtgcc
     6901 agacgcttca gttcgtcggt aaagggaatg ttgtcccagg ccacgccttc ttttatctca
     6961 tagcacggca cgcccacggc atcgagcgtc acctgcaccg ttcccgtggg gtaaggcacg
     7021 cgctcaatct gcgtgcgcag ccccttccgg gcgaacacat ccagaatctc gtccccatcc
     7081 gcatcggcac ctacggcact gaccacacgg ctgtcgaaac caaactgcga tgcatggtaa
     7141 gcaaagtttg ccggagcacc gcctatcttc tttccttcgg ggaggcagtc ccacagagcc
     7201 tcgcccatac ctactattat cttattcata atattatatt gtttaannnn nnnnnnnnnn
     7261 nnnnnnnnnn nncaaactca atgtcctacc cgctgcaaac ctaataaaaa agttcctaac
     7321 tatagaatga aaagttgcca attatctatt aaaaagtctc taagaactaa ggattatctc
     7381 tatcccaagg cttgggatag acatccgcaa ccttgggaca gatatccgca gccttgggat
     7441 atgtgtccgc agcctgcgaa caaagattac cgcttcatac gcagcatata gaagaacaag
     7501 tacactaccc ctaccgtcat cacagccacg gcaccgcttt gtcctacagc atcacttgcc
     7561 aagcccattg ctatcggaaa taccgtaccg ccgaagagcc ccataatcat caaaccggaa
     7621 acctcgttct tcttttgtgg catagcaaac aacgcctgag agaagataac cggaaagatg
     7681 ttcgaattgc cgaaaccgat aagggcaatg caaatgtata tcattgtctt ttcatggaaa
     7741 acgaacaacc ctaccatcgc agccaacata cataacacgc tgatgccgaa gaaggttcgg
     7801 ggagccatct tctgaagaat gaaggcgccg agaaagcaac ccgccgtgcg gaaaatgaag
     7861 taaaggctgg tggcaaagcc ggcatcggcc agcgtcatgc ccagacgctc catcaggatt
     7921 ttgggcgctg tggtattcgt acctacatca atgcccacat ggcacatgat gcccaggaag
     7981 cagagaaaga taaacggctt gcccagcagg gcgaggcact ccccgaaggt ggaagggcgt
     8041 ccctcttcct tttcctcgcg gatggaagta ccgctcagcc agagaatggc aatcaccgca
     8101 atgaccatat agaccgggaa cagcaccctc cagcccatgc ccagagacgg aatggcctgc
     8161 gtagctcccc acatggcgat gtatggagcc agaaacgaag caatggcttt tacaaactgt
     8221 ccgaaggtga gcgaacttgc cagccgctcg ccgcttacga tattggaaag cagcgggttg
     8281 agcgacgttt gcatcagcgc attgccgatg cccagcaatg agaacgagag cagcatcagc
     8341 acgtaaccgt ctccgaaaac cgggagaagc aaagaggcaa acgtgatgac aaggctgaga
     8401 agcaccgtct tcttgcgtcc gatgcggttc atcagcatac ccgtaggtac ggagaagatg
     8461 aggaaccaga agaacaccag agacgggaat atgttggctt gcgagtcggt caggttcaag
     8521 tcggccttca cgtagttgga ggcgatgccc accaaatcca caaagcccat ggcgaagaaa
     8581 caaagcatga ccggaaagag ctttgccaag gaagaattct tagtattttc catgctgaag
     8641 attattatct gttattttaa tccgagtttg tacacagtaa acgaggtgac attgcagctt
     8701 ccacctttag catagaaact gatgcggttg taaggttccg acgggaatac aagatttgtc
     8761 atggcaaaac gtccgtcgtt gccaaacgct tcaatgctcg acttgtctac gaacaagcgg
     8821 agtttcattt cattgccacc ctcgacagga gccacggtca ctgcagggaa gtccttgctg
     8881 aacgtcacct cgccactctt ggtacggtcc atggtgaacg tcttttccgc caggttatag
     8941 tacatctcca cctcctcgcc tttcgagtta aagagctgga atcctatcac atccgcatcc
     9001 ttgttcttga tggtcatttc gatttcatac gttccggaat tgtcattcag cagtttgtcc
     9061 agattatacg tgcggtctac cttgaaagca cgcttcttgc tgcctttatc cctcagtttc
     9121 agcaattcgg gagacggggt tacctttaca taggtttcac cctccgaggt atagagcgaa
     9181 aggtcgcgcg gcacggagtt ggcactacgg tattggcggg tgggcacatc gttggcatat
     9241 tgccagttgc tcatccatgc caatgcaatg gcacgtcctg caggagcatt gctccaagtg
     9301 acagttgcat aatggtcttt tccccagtcc atccatttcg tcactgcggg agactcgttc
     9361 acgaatctct ttccgtcaaa tgtccccacg aaatattgtg tggcagagcc accgaacggt
     9421 ccgcccggat tgaggttaca gacgagtacc cacttcttca gttccgtacc ttcaaccggc
     9481 agttcaagca ggtcgggaca ctcccagact ccgccgtgag caccttgtcc ttcaccgaat
     9541 ttgctctcca gcgtccagtt cttcaggtcg gcagaagagt atatctccat ttcctgccct
     9601 acggcaagaa ccataatcca tttcttggta tcttcgtgcc agatgacttt agggtcacgg
     9661 aagtcgcgct gcgtggaagt caggatggga tttcgcgcat acttcttgaa ggtttttccg
     9721 ttgtcaagac tataggccat gctctgcact tgacggtcgc ttgccgatgt atagaaggca
     9781 atgacggcac cggcaccgaa cccggccgta ttatccttgt cgacaacaca agagccactg
     9841 aaaattgttc ccagcgcatc gggcgaaatg gcatctccgt gatgctccca agtgacgagg
     9901 tccgtactgg tggcatgtcc ccaatgcatg ttcccccaca tggagccgta gggattatgc
     9961 tggtagaaca aatggtagac cccgtctttg tagaacattc cgttaggatc attcatccaa
    10021 ccgtaagccg ggctgaaatg atacaccgga cggtacttct cccggttcga aacatcgaat
    10081 tcatccgaca gtttcatttc ttcccagcat aaggccgaat ccggaataag ctggaagttg
    10141 aaagagagat gtttattatc gaagccggtc aaatcgaccg gaacaaaata gtcgacctta
    10201 ttgactgcca atcgcacgtt catactgcgt acaacatcat tgtccgctat catatacaat
    10261 tttgcctccg gagaagcctc ttccaccggc agtagcaaaa acttcttctg ctcgtcaatt
    10321 tggacgatac tctgtccgtc acccagatgt ttaatcacga aaggaggatt tatggcctgg
    10381 catgtgaaga cagccacggt agttcctaat ataaatacgg taagcatcct tctgattgtc
    10441 cgccaaaagt cttttaaatg aatcatgttt ctgttggtat taaattaatt atgtttttct
    10501 accatgcaaa gatacgccac caagcagcag gaggctatct tttttgtttc aaagcatact
    10561 acaaatgtta cattcagtct aaaataatac aaattaaatt cctcatctcc atattgattt
    10621 aagcatccag gcatccaact ccatcttcgt ccccttcttc tgcgcaaaaa gttcgatacc
    10681 ggtttgagcc tcgcccggat aggttaataa tgtgaataca tccttcccgt cattggcaaa
    10741 gatttcaata ctcgatttgt ctacaaatat atgcaaatgt atcttattat ctaccggttc
    10801 caccctggta tatgccatac ggctgaattt aggaatctgc acatcggagc aatgggtacg
    10861 gtcaatcacc agattatgtg aatccgtatc atagctgacc accactttgc gcccttcacc
    10921 cacacacaaa ttcaagccaa aggtgttgga tacgtcagta gaaaacgaag catcgagttc
    10981 gtagacattc tcatcgggaa caaagccggg taacctctgt gtccccaccg ataaagcacg
    11041 tttcaccgat gcaggcttat agcgaagtgt ttgcaactgt tccaccggct tctgtaccag
    11101 cctcacgcct tccttgtatg tcttcagttc caggttgcgg ggaatggacc aaaagccctt
    11161 cccatacttc gatggagcta ccggtgcata gtcccaggtt gcaacccagc ccatcgaaat
    11221 tttggaatcc aacgttccgt caaaatcctg aaatgtgcgg gatgcataaa agtccagccc
    11281 tttgtccaca tatagaggct ctgcaggatg gttctccatc agcttaaaag aagtgccgtc
    11341 gaagtctcct ataaagtatt gttcttgcgc ccagtttaca gatacgacca tcacccacct
    11401 tttcttgtca gaatccccgt caaccggcaa ctggaataaa tccgggcact cccaagactt
    11461 ttcactgtca ccggcagggc cgaaatcact ggtccaagtc cagctcttca aatcaggaga
    11521 ggtataaaac tttattttct tctccagggc cttggctaca accatcaccc atttttgggt
    11581 cggctcgtgc cagaagacgg tagggtccct gaattccgta ctccaaaggt ccaaaaccgg
    11641 gttaccttcg taataatgaa atgtctttcc gtcatgactg aaagagatgc cctgcgcttg
    11701 tttcttggag tccttctcaa aaacggtgta agccgccaca taagcaccct tgccgaaacc
    11761 ggccgtgttg ttcttgtcta cgactgcaga accggtgaag taactgatat tgtcatccgc
    11821 tccggtcatg gcataagggg ttatctgttg gtaatgtacc aaatctgtag attcgacttt
    11881 gccccaccag tacatatgat atttaccctg atagtacatg aatcccgagg ggtcaccaat
    11941 ccatcccttc tccggactga aatgatactg aggacgataa ggctctttgt ataaactgtc
    12001 tgaattcatt tgtgcaccgg cagacaatgt tcctgccact aaaagtgcac ccaatatagt
    12061 aggtatcttc attttctgta ttttcattaa aagttcatct ttacccttgc atctttcagt
    12121 ctccaaactt cggcagcaac ttccgttgta tttccatcag agaatagttc caatagcgta
    12181 ctgttttctt tcagaggaaa gattcttgta gtgaatgcat cctcatcatt aataaatcct
    12241 tccaccacag aaccgtcaat aaacaaacga atctccaccg gtttagcagt atccaaccga
    12301 taatgatcct tacgaatctt caaaggaatg tgtgcacgca aggaagaatg cgtctggtcc
    12361 acaataagtt cctccttctc cacatcataa taaatcaggc tatattcgct attatccgga
    12421 ttcttacaca atgtaaatcc aaaccgtttt gcgtcaccgg gataaaaagt cgccttgact
    12481 tcaagctgat gttcccttct gctcacaatg tgcggtttcg cagcagtcaa tgcctttctg
    12541 gaataaaccg tcggttgttc acgcaattgt ttcatcacgg gatggggtgt ttggcatagt
    12601 ttcccatctt tcagctgcca tcttctgggc atactgtaga gatgtgccca tccttgttca
    12661 taagtggcct cccctcctat ttcatcgggt ataatggcaa tggcagcaac atccccttcc
    12721 ggagtctcca caacagaggg ggacagcaag cggttgatga cctccagatt ttgagggact
    12781 gggttgtccg gtataaactt ttcattcttg aaatctccta tccaatactg gcaacgcgca
    12841 ggtatgcctt tatgaggaac cctattcacc aaaagaacat acttgccgcc catcttctta
    12901 aagaccggca tttcccagaa aataccggag tcatccactt ccggattgcc ctcaaacagc
    12961 aaatgtacaa aatcccatct cttcaagtcc gccgatttat aaagcagcaa agccccgtgg
    13021 ggtgtatcgg tctgctcaat gccgaaaccg ataatcatat accagacatc accctctttc
    13081 cagacatact ggtcacgcat gtccgtacgg gtatatccgg caggcttc
//
