LOCUS       c00043_gnlPro..        14175 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CHADNLBK_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 14:50:24
            Original ID  :: gnl|Prokka|CHADNLBK_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7344
            Orig. end    :: 21519
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14175
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[17344:20131]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12787
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..14175
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14175
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             71..181
                     /locus_tag="ctg43_19"
                     /transl_table=11
                     /translation="VILSCKPRGYLMQVWAIQSVIIWLWELNMNMRTTQA"
     CDS             complement(612..734)
                     /locus_tag="ctg43_20"
                     /transl_table=11
                     /translation="LAWHGICNPSPITQDSPKCICTFRGVLLYPKVLTMKGYLQ"
     CDS             complement(712..1473)
                     /locus_tag="ctg43_21"
                     /transl_table=11
                     /translation="MRIKVYEEQLEDGEKKEVQIYEGVYLEKVDADKRTFLDALPFIPK
                     KRRYNAYEPHCSGLYIGYSRLANDFLSFGASDKMGLDLSKSWEFGFNILSVYHNFKKNP
                     HWGINLGVSWGYRSFNIDGNYALLKENGTSIFTAGNEDTSYNKSRLRHFFFRVPVLMEW
                     QQRVGRNKVFFNAGPEFEIRHSVKSFSHINGGKKKTVGKGMYVQPVGINLLAQAGYGNI
                     GIYLRYSTYGLFQKDKGPEVSPYSFGVAWYL"
     CDS             complement(1638..2108)
                     /locus_tag="ctg43_22"
                     /transl_table=11
                     /translation="MKTSILICIRSLCLFSLLICLPAFVHAQERLQIADLFSKYGEQKD
                     VTRVELNGSILKSYRMTTYKSLVFKNVSPYRREIQQAIVHDKQDNAKKAQEVMESGVLR
                     SAYYQLKEVERNGKKLNRYIIFKIGKDSMGTLIYIEGLLSEKEMMDMLYKSE"
     CDS             complement(2121..2579)
                     /locus_tag="ctg43_23"
                     /transl_table=11
                     /translation="MKIDELLDKYFEGETSCEEERELRRFFTEEEVPEHLQTYRPLFAY
                     LNREATSMAEPTEEKSVTTESAKEVPAQRKPFRLYRTFYAVSGIAAGLLLLLGVAKIIF
                     PLSGVPENYVVIDGQRYTDEKLVEAKALEALQNASFTDEDLSNLLFQH"
     CDS             complement(2576..3049)
                     /locus_tag="ctg43_24"
                     /transl_table=11
                     /translation="LNYARKLTDEPEDAEDAVQEVLLKLWNKRLELEQYRSIEAFAMTL
                     THNICIDMWRCKRNDNLSLDIVQAASPTGTPERLLEIKDEIRLMHEIIHSLPNLQRTIM
                     QMKDIEGYETDEIAEITGCGPEAIRSNLSRARKKVRDVYLRTIQERKERRNEP"
     CDS             complement(3225..3782)
                     /locus_tag="ctg43_25"
                     /transl_table=11
                     /translation="MKKFRCTVCGYVYEGDAAPEKCPLCKAPASKFVEVEEATADGPLV
                     FADEHVIGVAKGCDDEMIKDLNNHFMGECTEVGMYLAMSRQADREGYPEVAEAFKRYAW
                     EEAEHASKFAELLGDCVWDTKTNLEKRMNAESGACEDKKRIATRAKALNLDAIHDTVHE
                     MAKDEARHGKGFEGLYNRYFKK"
     CDS             complement(3809..4243)
                     /locus_tag="ctg43_26"
                     /transl_table=11
                     /translation="MDVVKRLQNHNIKPSVQRIAIMNYLIEHRTHPTVDEIYTALSPSI
                     PTLSKTTVYNTLKLLSEQGAAQTLTIDERNTCYDADTSPHGHFLCKRCGKIYDLMCNNN
                     IKKVVDMDMDGHDVQEIHYYYKGICKHCIEEERLRTTKNN"
     CDS             4573..6465
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_27"
                     /sec_met_domain="CN_hydrolase (E-value: 1.4e-19, bitscore:
                     61.8, seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_synthase (E-value: 1.4e-32, bitscore:
                     104.1, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VPRVKVADCKFNASEIEKEIIIADGKGVQIIAFPELCITGYTCGD
                     LFAQQLLLEEAEMGLIQILNNTRQMDIISILGMPVALNGVLLNAAVVIQKGRVLGVVPK
                     TYLPNYKEFYEKRWFTSACDVAENSVRLCGQIIPMGRDLLFETADTTFGVEICEDLWAP
                     IPPSSTLALQGAEILFNLSADNEGIGKHNYLRSLISQQSARCIAGYVFSSCGFGESTTD
                     VVFAGNGLIYENGTLLAANERFSFEGQVVISEIDVEHLRTERRVNTTFAACHANCVSAL
                     PVRISTEYVNSRDLNLTRTFEPHPFVPQGIALDERCEEVFSIQVSGLAQRLVHTKAKSA
                     VIGISGGLDSTLALLVCVKTFDKLGWSRQGIVGVTMPGFGTTDRTYTNAIDLMNSLGVT
                     VREVSIKEACIQHFKDIDHDVHVHDVVYENAQARERTQILMDIANQTWGMVIGTGDLSE
                     LALGWATYNGDHMSMYGVNASVPKTLVKHLVKWVAEHDMDDASRATLLDIVDTPISPEL
                     IPADENGNIQQITEDLVGPYELHDFFLYYFLRCGFRPSKIFFLAARTFKGMYDEETIKK
                     WLQTFCRRFFNQQFKRSCLPDGPKVGSISLSPRGDWRMPSDASSEMWLREVEGL"
     CDS             6438..6629
                     /locus_tag="ctg43_28"
                     /transl_table=11
                     /translation="VAKGGGRTLILYFGYAVISIWVFDDCILFAFLLHVFCSATANVLQ
                     YHCNGFAVALQNVCRILQ"
     CDS             complement(6694..7335)
                     /locus_tag="ctg43_29"
                     /transl_table=11
                     /translation="LSGFHYKLIEAFARDHGLQAAISPEMSFNKRLEGLADGQYDVIAY
                     GILATSELKDSLLLTTPIVLNKQVLVQRKLENISDSSLFIKSQLDLAGKTLHVVKGSPS
                     ILRIRNLGNEIGDTIYVEEIEKYGSEQLIALVAHGDIDYAVCDESIARTAADSIPQIDI
                     NTAISFTQFYSWGVSKQSPILLDSLNTWLDSFKKGKEYKKIYKRYYGKRN"
     CDS             7384..7539
                     /locus_tag="ctg43_30"
                     /transl_table=11
                     /translation="MYDAFGSYLGIIARMTFRFLFFLDEIVGNESRCNSQKCVFEQSAF
                     RHTVIC"
     CDS             complement(7536..9665)
                     /locus_tag="ctg43_31"
                     /transl_table=11
                     /translation="MNNRDRFGNQIDPNTQPDNLEDSTNTEIQSLPPKLYMWKLSETLG
                     NRTIIPADTASLNFQSTNLVEGMFGHYNYLGNLGSPRLSRLFFEREESEPTIFMAPFSS
                     FFTRPDQVLFTNSNVPYTNLTYYKAGNKVNGEERFKSYFSVNVNKQLAFGFNIDYLYGR
                     GYYQNQSTSHFNAGLFGSYIGEKYQVQAVYNNFFLKMNENGGIADDQYITRPENMSGGK
                     KEYESTTIPVKLEQSSNRNKDFYIYLTQRYRLGFTRRVRNTQEGKPTVSAPKASSSPSS
                     ESEISASNNDIALPNDSIASKSVSTLAAANDSLPSVSTADNDSLFEEEFVPVTSFIHTL
                     KVERSRHQFRSGSEPEGFFPEDYKLYKNYSNDSTTAFSVKNVFGIALLEGFNKYAKAGL
                     TAYISHKFSRYDLMNTDTLTDMRRIRYTEQEIFVGGELAKREGKLLHYNVNGEVGLVDK
                     AIGQFRVNANLDLNFRLWKDTVNFYARGYVSNTLPSFYMRHYHSNHYNWDNDNMDKEFR
                     TRVEGELNISHWGTNLRAGVENIKNYTYFNQSALPEQNGGNIQVLSATLKQDFRLGVFH
                     LDNEVTWQKTSNETVLPLPQLSLYHNFYILAKLAKKVLTVQLGADVRYFTKYNAPAYAP
                     GVQQFHLQPTDDLVEIGGYPIVNVYANLHLKRTRIFAMMYHVNAGMGSANSFLVPHYPI
                     NPRLFKIGVSWNFYD"
     CDS             complement(10001..10546)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_32"
                     /sec_met_domain="POR (E-value: 3.6e-36, bitscore: 116.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDEKISSPILSKYDAAIILNQPSLEKFESKVKPGGVLIYDGYGIINPPTR
                     KDIHVYRINAMDAANEMNNAKAFNMIVLGGLLKIKPMVTLDSVLRGLKKTLPERHHHLI
                     PMNEEAIKKGMELIQEMK"
     CDS             complement(10569..10979)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_33"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.6e-14, bitscore:
                     43.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNRGENITIIFINNAIYGMTGGQMAPTTLVGMKTSTSPYGRDVHL
                     HGYPLKMADIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMAGKGSNLVEIVST
                     CNSGWKMSPAKSNEWMVENMFPFYPLGDLKDK"
     CDS             11028..11408
                     /locus_tag="ctg43_34"
                     /transl_table=11
                     /translation="LVSEHQAVWPKALDGSGKCGRTSMGGFLPVDVYIIIDEHGTSHRG
                     DAYCFVFQSHFFDNFGYEFMNYAVTASRAVVHGIVVHQSRFLGNQILGLYNIFFCHNHF
                     SYLLVNRMKNSINLTNIAAPQT"
     CDS             11409..11522
                     /locus_tag="ctg43_35"
                     /transl_table=11
                     /translation="MNSLKSSFAAKYIMIAAKASTMKRMFSTFLILSGFIS"
     CDS             complement(11512..12597)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_36"
                     /sec_met_domain="PFOR_II (E-value: 1.6e-28, bitscore: 90.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.8e-49, bitscore: 158.3,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKMVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVGLAFELAFK
                     YRNPAIILADGVIGQMMEKVVLPVQKPRRTDAEVIEQCPWATTGRTNGRKPNVITSLEL
                     KPEEMEKNNIRFQAKYKQIEENEVRFEEIHCDDADYLIVAFGSMARIGQKAMELAREEG
                     IKVGMLRPITLWPFPTKAIAAYADKVKGMLVTELNAGQMVEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVDALKEKLIKK"
     CDS             complement(12617..12787)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_37"
                     /sec_met_domain="Fer4_7 (E-value: 5.3e-11, bitscore: 34.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.2e-08, bitscore: 25.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.5e-05, bitscore: 15.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LCVVACPLNVIALTKEVNVKGYNYAHQILEDTCNGCASCATVCPD
                     GCISVYKIKVE"
     CDS             12798..13142
                     /locus_tag="ctg43_38"
                     /transl_table=11
                     /translation="LQRSVSTTIAPLIFAIIYVLYLLIVHILVVEVQDVHSHLIGMLCR
                     AFGVQVDGILIVVQCLLPVALFPIGISPQVVSFVFAGKVCLQYFVKLLDGLLYISLVDK
                     LFYGIQSFHI"
     CDS             13191..13292
                     /locus_tag="ctg43_39"
                     /transl_table=11
                     /translation="MSIFTVKNKKKGQIKSPKFLTILSECQSFGRIS"
     CDS             13265..13513
                     /locus_tag="ctg43_40"
                     /transl_table=11
                     /translation="MSELRADIIKKVILLLYKCTGILSTLRWWRPPSNGVLKNSLIIMS
                     ASSVLMNRPGMTSTLASLCWRAKWAISAVQQRAARIP"
     CDS             13513..13641
                     /locus_tag="ctg43_41"
                     /transl_table=11
                     /translation="MLVQRYADTFTASADGNSRIALSGFNGQCQRMCKVGIVATLG"
     CDS             13973..14161
                     /locus_tag="ctg43_42"
                     /transl_table=11
                     /translation="LQCDGQTGCQAEYLGTTRDNAFLISRSLATEQTFGRNGHDTHLDA
                     ILAQQFSTGYQCGNFRA"
ORIGIN
        1 gctggggatg aaactcctac tcgtaccact gtggatactt attctgcatt aggcggtaga
       61 gatatggacc gtgattttaa gctgcaaacc ccgtgggtat ttaatgcaag tttgggctat
      121 acagtcggta ataatctggc tttgggagct gaatatgaat atgaggacta ctcaagcatg
      181 aagttcaaat atcctgaagg tgatgagatg gcatgggaaa cgggtgaggc tgacctctgt
      241 atgaaggggg taagtacgct tcgtttagga gcagaataca agccgatacc tgctttctct
      301 ctgcgtgccg gttacaatta cagtactgca gcctataaaa aggatgctat taaggcattg
      361 ccttccaatt ctataaatac agatacggat tttgccaata gcaaatcgat gaatactttc
      421 actttaggta tcggttatcg cttttcttcg ttttatgcgg atttggctta taaattcgat
      481 acttataaat ctgatttcta tccgttttat aatgatataa atggcttggt aacaccgcca
      541 acaacggaag ttaccaacac tcgcagtaaa gtgctattta cattgggcat gcgtttttag
      601 aagaacaatt tttattgcag ataacctttc attgtcaata ccttagggta taaaagaact
      661 ccccggaatg tacaaataca tttcggggag tcttgtgtta taggggaggg attacagata
      721 ccatgccacg ccaaatgaat agggagatac ttccggtccc ttgtctttct ggaataatcc
      781 gtatgtggag tagcgcaggt aaatgccgat attaccataa ccggcttgtg ccagcaggtt
      841 tatgccgacg ggctgcacat acataccttt gcctacggtt ttcttcttgc ctccgttgat
      901 gtgtgagaat gacttcacgc tgtgacgtat ctcaaattcg ggaccggcat tgaagaacac
      961 tttgtttctt cccactcttt gctgccattc catcaatacg ggtacacgga agaagaaatg
     1021 gcgcagacgg cttttattgt aactggtgtc ttcgttgcct gcggtgaaga tgctggttcc
     1081 gttttccttc agcaaggcat agttaccgtc gatattgaaa gaacggtatc cccagctgac
     1141 tcccaggttg attccccaat gcgggttctt cttgaagttg tgatatacgg agaggatgtt
     1201 gaagccgaat tcccatgact tggataagtc gagtcccatc ttgtcgcttg ctccgaagga
     1261 aaggaagtcg ttagccagcc ggctgtagcc aatatacaga ccggaacagt gcggttcgta
     1321 agcattgtat cttctctttt tggggatgaa tggcagtgcg tcgaggaaag tgcgcttgtc
     1381 tgcatccact ttctcgagat agactccttc ataaatttgt acttctttct tttctccgtc
     1441 ttccaactgc tcttcgtaca ccttgatgcg catgtctcct tttcctttcc ggatgatgat
     1501 ggagtcgcct tgtgtctgta ctgtagcttt ctgttcaggg tcagtctgtt gttgtgctgc
     1561 catgcggccg gccggcacag caagcaggca ggccaaaatc ataattctgg ttttcatatc
     1621 gtatattgtt tttagtgtta ttccgatttg taaagcatat ccatcatttc cttttcactg
     1681 agcagaccct ctatgtaaat caaagtgccc atggagtctt ttcctatctt gaaaatgatg
     1741 tagcggttca gcttctttcc attgcgttcc acctctttca gttggtaata agcgctacgc
     1801 agcacaccgc tttccattac ctcctgcgcc ttctttgcgt tatcttgctt gtcgtgtaca
     1861 atggcctgct gaatttcccg gcgatagggg gatacattct tgaacacaag gctcttgtag
     1921 gtagtcatgc ggtaagattt caggatactg ccgttcagtt ctaccctggt cacgtccttt
     1981 tgctcgccat acttgctgaa taggtcggct atttgcagtc tctcttgtgc atgtacaaag
     2041 gctggcaggc aaatcagcag ggaaaagagg cacagactac gtatgcaaat cagtatagat
     2101 gttttcataa ccttgttata ttagtgttga aacagtaagt tgcttaaatc ttcatccgtg
     2161 aagctggcgt tctgcagggc ttctagtgct ttggcttcca ccagtttctc gtctgtatac
     2221 cgctggccgt cgatgacgac ataattttcg ggaacaccgg aaagcggaaa tataatctta
     2281 gctaccccga gaagcaggag caatccggcg gcaatgccgc tgacagcata gaatgtgcga
     2341 tagagacgga aaggcttccg ctgtgcgggt acttcctttg ccgattctgt tgttacggat
     2401 ttttcctctg tcggttctgc cattgaagtt gcttcccggt tcagataagc gaataggggg
     2461 cggtacgttt gcaggtgctc cggcacttcc tcttcggtaa agaaacggcg cagttcacgc
     2521 tcttcttcgc aggaagtttc cccttcgaaa tatttatcca gcagttcatc tatcttcatg
     2581 gctcatttct cctttctttt ctttcttgta tggttcgcag gtaaacgtct ctcactttct
     2641 tccgggctct tgacagattg ctgcggatgg cttccggtcc gcatcccgtg atttcggcga
     2701 tttcgtccgt ttcgtatcct tcgatgtctt tcatctgcat gatggtgcgt tgaagattgg
     2761 gcagcgagtg gatgatttcg tgcatcaagc ggatttcatc tttgatttcc aacagccgtt
     2821 ccggtgttcc ggtgggggat gccgcctgca caatgtcaag agataggttg tcgttgcgtt
     2881 tgcagcgcca catatctata cagatgttgt gcgtcaacgt catggcaaat gcttcgatgc
     2941 tccggtattg ctccagttca agccttttgt tccatagctt gagcagtacc tcctggacgg
     3001 catcttctgc atcctccggt tcgtcggtca acttccgtgc atagttcaac agcttggcac
     3061 ggagtggaag aacggttatt ttgaattctt tgagttccat ttacacagat aagacgaatg
     3121 ggaaatacaa acgtgacatt gtaaagtgaa aaaagttgga ataaaaaaag ggacttacta
     3181 acattagcag tcccttttct tcacattact ataaaagtat aggattattt cttgaaatag
     3241 cggttgtaca gaccttcgaa acctttaccg tgacgggctt cgtccttagc catttcgtga
     3301 acggtgtcat ggatagcgtc gaggttcaat gctttggcac gggtagcgat acgcttcttg
     3361 tcttcgcatg cacctgattc tgcgttcatt ctcttttcga ggtttgtctt ggtgtcccat
     3421 acgcagtcgc ccagcagttc ggcaaacttg gaagcgtgtt ctgcttcttc ccaagcgtaa
     3481 cgcttgaaag cttctgcaac ttcgggataa ccttcacggt ctgcctggcg gctcattgcc
     3541 aagtacatac caacttctgt acattcgccc atgaagtggt tgtttaggtc cttaatcatt
     3601 tcgtcgtcgc aacctttggc tacgccgatt acgtgttcgt cggcaaatac cagcgggccg
     3661 tcagctgttg cttcttcaac ttctacgaac ttgcttgcgg gagctttaca caatgggcac
     3721 ttttcgggag ctgcatctcc ttcgtatacg taaccgcata cagtacatct aaattttttc
     3781 attttctctc agattttaat tagttgaatt agttattctt tgttgttctt aaacgttctt
     3841 cttctatgca atgtttacag attcctttat aatagtagtg gatttcctgc acatcgtgcc
     3901 cgtccatatc catgtcgacc actttcttga tgttgttatt gcacatcaag tcataaatct
     3961 ttccgcaacg cttgcacaag aaatgaccgt gcgggctggt atcggcatca taacatgtgt
     4021 tacgctcgtc gatagtcagg gtttgtgcgg caccttgctc gctcagtagt ttcaaggtat
     4081 tgtataccgt tgttttagac agtgtcggta tggagggaga cagtgccgta tagatttcat
     4141 ccaccgtggg atgcgtacga tgctctatca agtaattcat gatggctatg cgctgtactg
     4201 aaggcttgat attatgattc tgcaatcgtt ttactacatc catataatct aaagtttcaa
     4261 acttgtaatt attacatttt taattcactt gcaaagatag gaagttccta taattctcca
     4321 aaagattttt ggaaaatttt tagttgcggt cattaaaatt gtttatatat gttcctcttc
     4381 ttgtaggtag gttgccgtat ttttgtcata aaagcgaagg caggatgcac ccggttttag
     4441 tcagtttctc gtgccgatat agataaaacg tttttccctt atctctctta atcagaattt
     4501 tgccgtatct ttgcaccgaa taaataatat agcatcctta tgaattacgg atatgtaaaa
     4561 gtagcggcgg ctgtgccccg tgtcaaggtg gctgactgta agttcaatgc ctcagagatt
     4621 gaaaaagaga ttattatagc cgatgggaaa ggtgtgcaaa tcattgcttt tccggagttg
     4681 tgcattaccg gatatacttg tggcgacctc tttgcccagc aacttctgct cgaagaggcg
     4741 gaaatggggc tgatacagat tctgaacaat acgcgccaga tggatatcat ttcgatattg
     4801 ggcatgcccg ttgcactgaa cggtgtgttg ctgaatgcgg cggttgtcat tcagaagggg
     4861 agagtgctgg gcgttgtccc gaagacttat cttcccaatt ataaggagtt ttatgagaag
     4921 cgctggttta cttccgcatg tgatgtggca gaaaacagtg tgcgcctttg cgggcagatt
     4981 attccgatgg ggagagacct gctgttcgaa acggcagata ccactttcgg agtggagata
     5041 tgcgaagatt tgtgggcacc cataccgccc agttccacgc tggcactgca aggtgcggaa
     5101 atcttgttca atctttcggc cgacaatgaa ggtatcggca agcacaatta tctgcgctcg
     5161 cttatcagcc agcagtcggc acggtgcatt gccggttatg tattcagctc atgcggtttc
     5221 ggagaatcca ctacggatgt ggtgtttgcc ggcaacggac tgatttatga gaacgggact
     5281 ctgctggcgg caaacgaacg cttctctttc gaagggcagg tggtcatcag tgaaattgat
     5341 gtggaacact tgcgtacgga gcgccgggtg aatacgacct tcgcggcttg ccatgcaaat
     5401 tgtgtttcgg cccttccggt acgaatctct acggagtatg tcaacagcag ggatttgaac
     5461 ctgacacgta cttttgaacc gcatccattt gttccgcagg ggatagcgtt ggacgaacgc
     5521 tgtgaggagg tattctccat ccaggtgtcc ggactggcgc aacgtctggt gcatactaaa
     5581 gcgaagagtg ccgttatcgg catttcgggt ggactggatt ctacgctggc gctgctggtt
     5641 tgcgtaaaga ctttcgataa gttgggatgg tcccgccagg gtattgtcgg tgtcaccatg
     5701 ccgggattcg gaacgaccga ccgtacttac acgaatgcca tcgacctgat gaactccctc
     5761 ggtgtgactg tccgcgaagt cagtatcaag gaggcctgca tacagcattt caaagacata
     5821 gaccatgatg tccatgtgca cgacgtggtt tacgagaatg cgcaggcacg ggagcgtacc
     5881 caaatcttga tggatattgc caaccagacc tggggaatgg ttatcggtac gggcgacctt
     5941 tcggaacttg ctttaggatg ggccacttac aacggcgatc acatgtcgat gtacggtgtg
     6001 aatgccagcg tccccaagac tctggtgaag cacttggtga aatgggtggc agagcatgat
     6061 atggacgatg cttcacgtgc taccttgctc gatattgtgg atactcccat cagcccggaa
     6121 ctgattccgg cagatgagaa cggtaatatc cagcagatta ccgaggattt ggtggggccg
     6181 tatgagcttc acgacttctt cctttattac ttcctgcgct gcggtttccg tccttccaag
     6241 atatttttcc tggcagcacg gacattcaag gggatgtatg atgaagaaac catcaaaaaa
     6301 tggttgcaga ctttctgccg tcgtttcttc aaccagcagt tcaagcgttc ctgtttgccg
     6361 gatggtccga aggtgggcag tatctctctg agtccgcgcg gtgattggag aatgccgagc
     6421 gatgcttcgt cggagatgtg gctaagggag gtggaaggac tctaattctt tacttcgggt
     6481 atgccgtaat atcgatatgg gtatttgatg actgcatctt gtttgcattc ttgctgcatg
     6541 tattttgcag tgcgactgca aacgtgttgc agtatcactg caacggcttt gcagtggcac
     6601 tgcaaaatgt atgcaggatt ttgcagtaat aagctgctga ttgataacta gttgtaaaag
     6661 tagggatatg ctgcgtgtat ggaaaagtgc agcttagttt cgtttcccgt agtatcgttt
     6721 gtagattttc ttgtattctt ttcccttttt gaaactatcc agccatgtgt tgaggctgtc
     6781 cagcaggata ggggactgtt tgcttacccc ccaggaatag aattgcgtga agctgatggc
     6841 ggtattgatg tctatttgag gaatgctgtc ggctgcggta cgggcaatgc tttcgtcgca
     6901 tacggcatag tcgatgtctc catgggctac caaggcaatc agttgttcgg aaccgtactt
     6961 ctctatttcc tcaacgtaga tggtgtcgcc tatctcattt cccaggttgc ggatgcgtag
     7021 tatggaaggg gagcctttca ctacgtgcag tgtctttcca gccaggtcca gttggctttt
     7081 gatgaataat gacgagtcgg aaatattctc aagcttgcgt tgcaccagca cttgcttgtt
     7141 cagcacaata ggggtggtaa gcagcaagga gtctttcagc tcactggtgg cgaggatgcc
     7201 gtaggcaatc acgtcatatt gcccgtcggc caggccttcc agccgcttgt tgaagctcat
     7261 ttccggtgat atggccgctt gcagcccgtg gtcgcgtgca aaagcttcta tcagcttgta
     7321 gtggaaaccg gacaaggtgt catcatccac atagaaactg atggagttgt attccgtcga
     7381 agcatgtatg atgccttcgg cagttatctc ggcataatcg cgcggatgac ctttcggttt
     7441 ctcttctttc ttgatgagat agtgggcaat gagagccgct gcaattccca gaagtgcgta
     7501 tttgagcagt ctgcttttcg tcatacagtc atctgttagt catagaaatt ccatgagacg
     7561 ccaattttga acaagcgcgg attgatgggg tagtgcggca ccaggaagga attggcgctt
     7621 cccatacccg cgttgacgtg atacatcatg gcaaagatac gcgtccgctt caagtgcagg
     7681 ttagcatata cgtttacgat ggggtaaccg cctatttcca ccaaatcgtc cgtaggttgc
     7741 agatggaatt gctggacgcc gggtgcatag gcgggtgcgt tgtacttggt gaagtaacgg
     7801 acatcggcac ccaactgaac ggtcagcacc ttcttggcga gtttagccaa tatgtagaag
     7861 ttatggtaga gcgagagttg gggcagtgga agtactgttt cattgctcgt cttctgccag
     7921 gtcacctcgt tgtccaggtg gaagacaccg aggcggaagt cttgtttcag cgtggcagac
     7981 agcacttgta tgttgcctcc gttctgttcg ggcagggcgc tttggttgaa gtaagtgtag
     8041 ttctttatat tctctacacc ggcacggaga ttggttcccc aatgggaaat gttcagctcg
     8101 ccttccacac gcgtacggaa ttctttgtcc atgttgtcat tgtcccagtt gtagtggttg
     8161 gagtgataat gacgcatata gaaggaagga agcgtgttgc tcacataacc gcgggcgtag
     8221 aagttcaccg tatctttcca tagacggaag ttcaggtcca gattggcgtt gacgcggaac
     8281 tgcccgatgg ctttgtctac caaccccact tcaccgttta cgttgtagtg caacagtttg
     8341 ccttcgcgct tggcgagctc gccgcccacg aagatttcct gttcggtgta gcggatgcgg
     8401 cgcatgtcgg taagcgtgtc cgtgttcatc aggtcgtacc ggctgaactt gtgggagata
     8461 taagccgtaa gtccggcttt ggcatatttg ttgaaacctt ccagcaaggc tattccgaac
     8521 acgttcttta cactgaatgc cgtggtggag tcgttgctgt aattcttgta aagcttgtag
     8581 tcttccggga agaatccttc gggctcgctt cccgaacgga attggtgccg cgaccgctct
     8641 actttcaagg tatggataaa gctggtgacg gggacgaact cttcttcgaa aagtgagtcg
     8701 ttgtctgcgg tagaaacaga cggcaggctg tcattggcag ctgcaagtgt gctgaccgat
     8761 tttgatgcta tgctgtcgtt tggcaatgct atgtcgttgt tcgaagcgga tatttcggat
     8821 tcagaggacg gggaggatga ggctttgggt gcggataccg tcggtttgcc ttcttgtgtg
     8881 ttccgtactc tccgcgtaaa accaagacga tagcgctgtg tcagatagat ataaaaatcc
     8941 ttgttacggt tggaactctg ttccaatttg accggaatag tggtggactc gtactctttc
     9001 tttcctccgg acatgttttc gggacgggtg atgtattggt cgtctgcaat accgccgttc
     9061 tcgttcatct tcaggaaaaa gttgttgtag actgcttgta cctggtattt ctcgccgata
     9121 tagctaccga acagtcctgc attgaagtgc gaggtggact ggttctggta ataaccgcgc
     9181 ccgtacagat agtcgatgtt gaagccaaat gccaactgct tgttgacgtt gacggagaaa
     9241 taggacttga agcgttcttc accgttcact ttgttgccgg ccttgtagta ggtaagattg
     9301 gtgtaaggca cgttgctgtt ggtgaaaagc acctggtcgg gacgtgtgaa aaaactggag
     9361 aagggagcca tgaagatggt aggttcgctt tcctcccgtt cgaagaacag acgtgagaga
     9421 cgtggagaac ctaaatttcc caagtagttg tagtggccga acattccttc caccagattg
     9481 gtgctctgga agttgaggct ggctgtgtcg gcaggtatga tggtacggtt gcccagtgtc
     9541 tcacttagtt tccacatgta aagcttgggt ggaagacttt gaatctcagt attggtactg
     9601 tcttccagat tgtccggctg ggtattcggg tcaatctggt taccgaaccg gtcgcgattg
     9661 ttcatcgggt ttaaggtgtt ttgcgccata gccccccata tccctataac ggacagaaat
     9721 atatatgtca gtacaattcg tctcataatt aggcgcaaag atacaataaa aaattatttg
     9781 cttactgaat tcagcctttt ttgcttcttt taaactgtct tgttttctgt tttgttctat
     9841 actgcttccg gttctctgcc cttgaatcca tactttttcc ggcttgaaat gaaataagcc
     9901 cttgcaataa atcaatatca caagggctta tccgttttcc tttatctctt attctggcgt
     9961 aaagttcctc ctcttatggg gagtggcttt acatagcctt tcatttcatt tcctgaataa
    10021 gttccattcc tttcttgata gcttcttcgt tcatcggtat caagtggtgg tggcgttcgg
    10081 gcagtgtctt cttcaatcct ctgagtacac tgtccagtgt aaccatcggc ttgattttca
    10141 ataatccacc caatacaatc atgttgaatg ccttggcgtt gttcatttca ttggcggcat
    10201 ccatggcgtt gatgcggtaa acgtggatgt ccttacgcgt cggcgggttg atgatgccgt
    10261 aaccgtcgta gataagtacg cctccgggtt ttaccttgct ttcgaatttc tccagtgacg
    10321 gctggttcag gatgatggcg gcatcgtact tgcttaagat gggtgaggat attttctcgt
    10381 cacttacgat gactgttacg ttggctgtac caccacgttg ttccggtccg taagccggca
    10441 tccaagtcac ctctttgcct tccatcaatc cggaatatgc caaaatcttt cccatggaca
    10501 atacaccttg tccaccgaag cctgctataa tgatttcttc tttcattgtt cttctgtctt
    10561 tagcatgatt atttatcttt caggtcgccc agcggataga aggggaacat gttctctacc
    10621 atccattcat tggatttcgc aggagacatc ttccagccgg agttacaggt ggaaacgatt
    10681 tccacaaggt tggaaccttt gcctgccata gagttctcga atgctttgcg gatagccttt
    10741 ttcgctttgc ggatggcggg aacggactgt acgctttggc gtgtcacgta agcggttcct
    10801 tccaattgtg cagcaatatc ggccatcttc agcggatagc cgtgcagatg cacgtcacgt
    10861 ccgtaagggc tggtcgatgt cttcatgcct acaagggtag tgggagccat ttgtcccccg
    10921 gtcataccat agatggcatt gttgatgaag atgatggtga tgttttcgcc gcggttcaag
    10981 gcgtggatgg tttcggcagt accgatacaa gccaggtcgc cgtctccttg gtaagtgaac
    11041 accaggcggt ctggccaaag gcgcttgatg gcagtggcaa gtgcgggcgc acgtccatgg
    11101 gcggcttcct gccagtcgat gtctatataa ttatagatga acacggcaca tcccacaggg
    11161 gagatgccta ttgctttgtc ttccagtccc atttcttcga taacttcggc tacgagttta
    11221 tgaactacgc cgtgactgca tcccgggcag tagtgcatgg gattgtcgtt catcagagtc
    11281 ggtttcttgg caaccagatt ctcgggcttt ataatatctt cttttgtcat aatcacttct
    11341 cctatctgtt ggtgaaccgt atgaaaaact ccatcaactt gacgaatatc gccgcgccgc
    11401 agacgtagat gaacagcttg aagtcatctt ttgcagcaaa atatataatg atagctgcca
    11461 aggcaagtac catgaagaga atgttcagta cgtttcttat tttatcagga ttcatttctt
    11521 aatcagtttt tctttcaatg catctactat ctcatccgga tcgggaacaa tgccgccgag
    11581 gcgtccgaaa tgttccactt tcactttacc gttcacggca aggcggacat cttccaccat
    11641 ctgtccggca ttcaattctg taacgagcat acctttcacc ttgtcggcat acgcggcaat
    11701 ggctttggtc gggaacggcc acaacgtgat ggggcggagc atacctacct tgattccttc
    11761 ttcgcgtgcc agctccattg ctttctgtcc gatgcgtgcc atagagccga aggctacaat
    11821 caggtagtcg gcatcatcgc aatgaatttc ctcgaagcga acctcattct cttctatctg
    11881 cttgtatttg gcctggaaac ggatgttgtt cttttccatt tcttccggtt tcagttccaa
    11941 tgaggtgatg acgttgggtt tgcggccatt ggttctgccg gtagtggccc atgggcattg
    12001 ttcgatgact tccgcatcgg tgcggcgtgg cttttgtacc gggagcacca ctttttccat
    12061 catctggccg atgacaccgt cggcaaggat gattgccgga ttacggtatt tgaaggcaag
    12121 ttcgaatgcc agtcctacga aatctgccat ttcttgtacg gaagccggag caagggcaat
    12181 cagacgatag tcaccgtggc cgcctccttt tactgtctgg aaatagtcgg cctggctcgg
    12241 ttggatggtt cccagaccgg gaccgccgcg cataacgttt acaatcaagc aaggcagctc
    12301 ggcacctgcc agataagaga taccttcctg ctttaggctg acaccggggc tggaggagga
    12361 ggtcatgacc attttaccac ttccggcacc gccgtacacc atattgatag ctgccacttc
    12421 actttctgcc tgaagaacca ccatgccggt cgtctcccag ggtttcagtt cggcaagagt
    12481 ttccaatacc tccgattgcg gagtaatggg atatccgaag taaccgtctg caccgcaacg
    12541 gatggctgcg tgggcgatgg cttcgtttcc tttcattaat acaacttctt ctgccatatt
    12601 ctactgattt acagatttat tctactttta ttttatatac tgagatacat ccgtccggac
    12661 atactgtggc gcacgaggcg cagccgttac aagtatcttc caatatctgg tgggcatagt
    12721 tatacccttt cacattcacc tccttggtga gggctattac gttgagcgga cacgctacca
    12781 cacacaagtt gcagcctttg caacgttcgg tgtctactac gattgctcct ttgatttttg
    12841 ccataattta cgttctttat ttattgattg tacatatcct tgttgtagaa gttcaggatg
    12901 tccatagcca tttgataggc atgttgtgcc gggctttcgg ggttcaggtc gatggcatac
    12961 tgatagttgt tcagtgcttg ttgccagttg ccttgtttcc gataggcatt tccccgcagg
    13021 tagtaagctt cgtctttgcc gggaaagtct gtttgcagta tttcgtcaag ctgctggatg
    13081 gcttgctcta catttccctg gttgataagc tcttttatgg tattcagtcg ttccatatct
    13141 aaaaaatatc cgggttatcg aaccacaaag atagttttta tttgaagaca atgagcatct
    13201 tcactgtgaa aaataagaaa aaggggcaaa taaaaagccc gaagtttctc acgattctat
    13261 cagaatgtca gagcttcggg cggatatcat aaagaaggtg attctattgc tttacaagtg
    13321 taccggtatc ttgtccactc ttcgttggtg gcgtccgcct tcgaatggtg tactgaagaa
    13381 ttccctcata atcatgtcgg cttcttcggt actgatgaat cgccctggca tgacaagcac
    13441 attggcatca ttgtgctggc gtgccaaatg ggctatttct gccgtccagc agagggctgc
    13501 gcggataccc tgatgcttgt tcagcgttat gctgatacct tcaccgcttc cgcagatggc
    13561 aattcccgga tagcactctc cggcttcaac ggccagtgcc aaaggatgtg caaagtcggg
    13621 atagtcgcaa ctctcggttg agtaggtccc gaagtccttg taagcccagc ctttggcttc
    13681 caaccagccg cgaacatatt ccttcaattc gaagcctgca tggtcggaac agattcctat
    13741 tgttttcatg atggtcagtt aatataccaa tgtgccaatg tgctgatgcc tgcagcttgt
    13801 agggcgcggg caatcagcac atcagcacat tggataatga ttataacatt gcttttactt
    13861 gtttgtaaac gttctctgcg gtgaaaccga gcttttcgtc cagcacttta taaggtgccg
    13921 agaatccgaa tgattccaat ccccatactt taccgcgggg acctaccagc ccttgcagtg
    13981 tgacgggcag accggctgtc aggccgaata ccttggcacc acacgggata atgccttctt
    14041 gatatcccgg agcttggcta cggaacagac cttcggaagg aacggacacg atacgcacct
    14101 tgatgccatc cttgcgcagc aattcagtac cggctaccaa tgtggcaact tccgagcctg
    14161 aagcaacgag gatta
//
