LOCUS       c00095_gnlPro..        16110 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CHDPEPAM_95.
ACCESSION   c00095_gnlPro..
VERSION     c00095_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:29:03
            Original ID  :: gnl|Prokka|CHDPEPAM_95
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2184
            Orig. end    :: 18294
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16110
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12184:18170]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15986
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..16110
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16110
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1815..2978)
                     /locus_tag="ctg95_5"
                     /transl_table=11
                     /translation="MNKISLLFILSVLITFSAYAQDDIKITHAPYLQNLGENEVTVVWT
                     ANKPSIGWVELAPDDGTHYYQTERPKFFNAKNGIKLTSTVHSVHLTGLKPGTRYRYRVY
                     SQEVLSHVGWRVIYGNVAATSVYGKQPLTFLTSDHGRQSVNFAMVNDIHGKSDVLEKLV
                     SHCDLKKTDMFLFNGDMVSIFNNEKEIFEGFMDKATELFASEIPMYYTRGNHETRGSFA
                     TAFQDYFSPKQEHIYYMFRQGSVCFVILDSGEDKPDSDLEYAGITVYDQYRTEQAEWLK
                     KVLESKEYKEAPFKVVVCHMPPFGGWHGEQEVAEKFIPLLNNAGVDLMLCGHLHRYMRN
                     EPKDGVRFPVIVNSNNTVLKAEAGVKELNIRILDMEGKEVDKLTITK"
     CDS             complement(3840..3944)
                     /locus_tag="ctg95_6"
                     /transl_table=11
                     /translation="MNIMSVNGLWRKQTYFLFVHSRKGKHTFINITDI"
     CDS             complement(4613..6202)
                     /locus_tag="ctg95_7"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQTYAIAKSKRGVILRTSSDDESHKGFSTVEEVYTQIVSDLTTAKTLLADYNPDDMW
                     LINSKICSGILARVYLVMQNWDGAYNEAKIVYDQHSQLMTREQYRSGFDDMISGNYAEV
                     VWAMKYTADNNLGGSTQFNFWYNQDASYGEGYADGPIYSFLDYFVDEQFVKLFEEKEDR
                     YQFWKRTNNANTEINTKWAFDKYKHYGEDGGSVIQSATRPEVCLMRGAEMLLIMAEAAA
                     QKGNSGEALNLLNRLQVARNATPTTNAGGEALLEDIYVERRKELICEGQAGFYDLVRLQ
                     KRLVRIGESTTNPAGHYVWGMQYLNGYNALDPQPIGTLESNDYRFFCQIPQMEILNNDA
                     ISESDQNPWSGQ"
     CDS             complement(6221..9499)
                     /locus_tag="ctg95_8"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYS
                     FRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSE
                     KTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNL
                     KFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLS
                     GEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSL
                     LSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWI
                     DNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDL
                     KWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDL
                     RNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSL
                     YEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITN
                     NFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDADVLIPR
                     WSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVYVTGNNLLTF
                     GPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             complement(10001..11047)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_9"
                     /sec_met_domain="IlvN (E-value: 1.6e-48, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.6e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             complement(11089..11820)
                     /locus_tag="ctg95_10"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(11857..12411)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_11"
                     /sec_met_domain="ALS_ss_C (E-value: 1.5e-18, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(12424..14124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_12"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.4e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(14151..15986)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_13"
                     /sec_met_domain="ILVD_EDD (E-value: 3.3e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
ORIGIN
        1 gtttttactc cgggaataat aatcaaccgg aaagtttctt tgttcacctg attgtcgagg
       61 tgcaacaatc cttttttcac acggcatttt gtagataaga cctccggatg cagataagtg
      121 aaatcacgcc cgagggtatc agtcaataaa gccgagacat gtgtataatc cgtattcggg
      181 atcattaccc cgccttcata aaatcccagt tccccatcca tcacatgttc tccctgaaga
      241 gattcgatcg gataaaggac tgctatatcg gcgacatgtc ttccttcctg ccgcaaaata
      301 tagttgagac gggacaggaa cttattaaat gccggaagtg aatcgcggta cagttcgttc
      361 cgccaggata actcaggcag gaaagtaaca ttccgatcat tataccagac agcatgtggg
      421 ataagcgtat tgaccccttt cgtatattgt tccatggcta tgtggtaaag ctcttttaca
      481 ctgatattcc ccatagcgcc gtatgtttcg gacattacct ggcgtttgtc ccagttatag
      541 gcagaagaag aaaccacttt ataaaacaat tcggtcggac ggcctccgcc aattttgtca
      601 ataccgggaa tccccatata tttcccgcac aacatcaagt caccagaagt tcccaccgga
      661 ttcgcaatct cttcctgatc ctgatgaccg gtagagtaaa tgccatgggc agaagcccat
      721 tcaccgatta ttttcataaa accttcggaa tacaaatggg cacgcaagcc aaacagacgg
      781 ttccgcgcag attgcgtttc ctccccgatg tcataccata atgccggata cagtaattcg
      841 ggagattccc cgtaacggga gataaatttc tcgttaaacg cgtctgtcca gatacgtccc
      901 ttagcccggt acagggtcgg ttcatcaaaa aaagtttcta tgatcgtatt cccgaaatag
      961 ggagagaaac ggtcataata tgcctgatga gtttctttta caaacagcct gacggcttca
     1021 gggtccagat aatccacatt cgggtcgcca tctttcacac agacgaaaaa catgatcttc
     1081 caggctcctt ccggaacttt ccagttgagt ttaccggaac gaatatattg ttccagcgaa
     1141 atccgatgct tcgtcagcgt gtccattgca acgaccgaca tcagttttcc ggcaggaacg
     1201 acctgttcga atgattcgcc gacagctact ttatactcca ttttgtccag ccgcttgatc
     1261 gtggcatccg gatatttgtt catgaagcga ggtaccccat ccgcgttgat ggctcccata
     1321 cttccactcg gaaaaccata ctcatcatac agggacatat gcacatccag tttcttggct
     1381 tcctctataa tcttgctata aagattgaaa taatcgtctg acagatattc cggcttgaag
     1441 tcttgcccga aaggaaggat tgcacaaccg ccatacccgt cttttcggat catctgacgg
     1501 aattggtcca gcaattcgtt ttcattgacc gtcgcattat tccaaaacca caaaggaaca
     1561 ggcttatatt tattctccgg atttacaaaa gctgactcac tgacctgggc agatactcca
     1621 aacgagacaa aacacataca tatgacaaag aaaatacctt tcattaaaga ttctatttag
     1681 gttataccaa tgattaccgt ttttatgatt gtacaaatat agaacctctg cttcaacagg
     1741 ttattttcaa aactgattct attcttccta tttttgatag ttcagccgga ggatgtttct
     1801 cccatctata tgtcttattt ggttattgtc agcttatcca cctctttccc ctccatgtcc
     1861 agtatcctga tgtttaattc ttttacgcct gcttccgctt tcaataccgt attattggag
     1921 tttacaataa ccggaaaacg aacaccgtct ttcggttcat tccgcatata ccggtgaagg
     1981 tggccgcaaa gcatgagatc gacaccggca ttattgagta aggggataaa cttttcggca
     2041 acttcctgct caccatgcca accaccgaac ggaggcatat ggcaaactac gactttaaac
     2101 ggtgcttctt tatactcctt gctttcaagt accttcttca accattccgc ctgttccgta
     2161 cgatactggt catagactgt tatgccggca tattcaagat ccgaatccgg tttatcttcg
     2221 ccactgtcca ggataacaaa gcagacagat ccctggcgga acatataata gatgtgctcc
     2281 tgtttcggag agaaatagtc ctggaatgcg gtagcaaagg aaccgcgggt ttcatggttt
     2341 ccacgggtat agtacatcgg tatctcggag gcgaaaagct cggttgcctt atccataaag
     2401 ccttcgaata tttccttttc attgttgaaa atagagacca tatcgccatt gaacagaaac
     2461 atatcggtct ttttcagatc acaatgggaa accagttttt ccagcacatc actttttccg
     2521 tggatatcgt tgaccatggc aaagttcacg gattgcctgc catgatcgct ggtcaggaac
     2581 gtcagcggtt gcttgccgta aacagacgtt gccgccacat tcccgtaaat cacccgccag
     2641 ccgacatggc ttaacacttc ctgcgaatac acccggtagc gataacgtgt gccgggcttt
     2701 aaccctgtca gatgcacaga atggacggta gaggtcagct tgatgccatt cttcgcatta
     2761 aagaacttcg gacgctccgt ctgataataa tgagttccgt catcaggagc cagttccacc
     2821 cagccgatcg aaggcttgtt tgcagtccat acaacagtga cttcattttc tcccagattt
     2881 tgcagataag gggcatgcgt tatctttata tcatcctggg cataagcaga aaaagtgatt
     2941 aatacagaca aaataaacag caaactgatt ttattcatgg tatatctttt taagttgtta
     3001 acgatctcct acaaagatac attcttcatt tattccggca aaccctaccg ggattaaatc
     3061 ccgttatcta caggaaagaa gcacaccttc acagacacgc ctctcctttt atgactgatt
     3121 aaactatacc aaaagaattt gattcatttc ttatcagata tgaactatcc tgtccccgtg
     3181 cttgacacgg ggccgcagaa gaacaggcag tatcaaaaga tacatatagg atacggtttg
     3241 tgcttttgcg atcccgtgtc gagcacggga acgggatagt tcaaatattt ctatattgaa
     3301 acatcctttt gctgcggttg ccttgtttac tattgatgat ttactttttg ggatataaaa
     3361 gccaagtcct atccggagaa catactattg gatacaaagc gtcaggagag ttcctggaag
     3421 ttaaaggatt gtcaaaatga tattttatgt atgtgctgaa ggaattgtac gggcaaaggg
     3481 aaatgtcgat ctgtttttat agaaatctcg ccgacttacc tttgttcgct ttgacctgat
     3541 tgttgcaata ttcatatcac aaaaaatgta tattatctat gattgttacc catataccac
     3601 atctattcat aatttattaa catattgcta ttttacacac acatcaaaaa gcggttgctc
     3661 tggaaataaa aactgtctaa aaacatatga ttttcttttt taaaagcact aattgaggtg
     3721 tttttcttct ctaaacgaat aaaaactcca ctacaataga aatttatctc agtttaaacg
     3781 aaattgaaat ctgtttaaac taaaattttc ttcggtttaa acgagataaa aagtcgatat
     3841 cagatatctg ttatgttaat aaatgtatgc ttcccttttc tagaatgaac aaataaaaaa
     3901 taagtctgtt tcctccaaag gccatttaca ctcataatat tcatatatca ttcattttta
     3961 tatcattttg attttgccgt ctgtttggtt acaggaagtg aagtttccat acgacactga
     4021 tttgcatcaa ccgtttcact gatatcatgt ccactattat cggttgaaag agaaactatt
     4081 tttcgcaatg acatacgttt actggtaatt ctggatcagg tgaaaatact ggattccacg
     4141 catcgccagc gcctgacctt tgatgtgttt tttctgtggt acaaatatta tcaggcaact
     4201 ctttccgata tttattatga gagataaacc ggatttattt tctactaacc ctttcgacat
     4261 acgaaaaaag aagtaatctg gagccggaag taatcgaaaa gattgccaaa gcattagata
     4321 tacccgaaga agcaattacg gaactaggcg aagccacttc cattaatatc ttttccggca
     4381 cctggcaaga taatgctaat tgccagaatt ataatcctac atttaacccc ttagaaaaag
     4441 tcgttgaatt atacgaacgt ttattgaaag cggagcagga gaaggtggcc atgttacagg
     4501 aagtgctaaa ggacaaaaag taaaacagtg aacatcaaat gttacaaata aaagagaggg
     4561 aggcatgtaa taaacacctc cctctctttt atttatttac aacagatgaa acttactgcc
     4621 cgctccacgg attctgatct gattcggaga tcgcatcatt attcaggatt tccatttgcg
     4681 ggatttggca gaagaaacgg taatcgttcg actccagcgt ccctatcggt tgcggatcga
     4741 gcgcattata tccgttcaga tactgcatgc cccatacgta atgtccggca ggattggtag
     4801 ttgattcacc gatacgaacc aatctctttt gcaggcgcac caggtcataa aaaccggctt
     4861 gtccttcaca gatcaactct ttacggcgtt ccacatagat gtcttccagc aaagcttcgc
     4921 ctccggcatt ggttgtcggg gtagcattac gcgccacctg caaacggttc agcagattca
     4981 gagcctcgcc ggagttaccc ttttgggcag cagcctccgc cataatcagc agcatttcgg
     5041 ctccgcgcat caggcagact tccggacggg tggcgctttg aataacgctt ccgccgtctt
     5101 caccataatg cttgtatttg tcgaaagccc attttgtatt gatttccgta ttcgcattgt
     5161 tcgtacgttt ccagaactgg taacggtctt ctttttcttc aaatagtttc acaaactgct
     5221 catccacgaa gtagtcaagg aacgagtaga taggaccatc ggcataaccc tcgccgtagc
     5281 tggcatcctg gttataccag aaattgaact gcgtactacc gcccaggtta ttatcggcgg
     5341 tatatttcat ggcccatacc acttccgcat aattgccgga gatcatatcg tcgaaaccgg
     5401 aacggtattg ttcgcgggtc atcaactggc tgtgctggtc gtagacgatc ttggcttcat
     5461 tgtaagcgcc gtcccagttc tgcatcacca gataaacacg ggccaggatt cccgaacata
     5521 ttttggagtt gatcagccac atatcgtccg gattataatc ggcaagcaat gttttagccg
     5581 tcgtcaggtc ggacacaatc tgggtataga cttcctctac agtagaaaaa cctttatggg
     5641 attcatcatc ggaagaggta cgcaggatca ccccacgctt gcttttagct atcgcatacg
     5701 tctgctggta attctggatc agatggaaat actggattcc acgcatcgcc aacgcctggc
     5761 ctttgatatg ttttttctgt gtttcatcac cggcggcggc atccacattg gtcaggatga
     5821 tattggcacg gttgatcaca ttatagcaca tcgaccagat ttttgaggca tttccgtcag
     5881 cctgtgtttt tgagttggaa tactggtatg ctgttacctg atcacctccc atattggtat
     5941 ggctgatcac gtcggcacca ctcgcatcga catacatctg gaatccggga agaccggcat
     6001 acacacggtc tcctttatca gtattaaaat acagctgctt ataggctgaa gtcaatactt
     6061 tttccaactg ggagacattc cccagtacat cttcatcgtt tactttcacg taggagctgg
     6121 ttgtcaggtc gtcgttacat ccggtcaggg ccataccagc aaaaaccagg gacaggaagg
     6181 atatatttat aaatcgtttc ataaatatca ttttttacgt ttacaatgtg atttgaatac
     6241 cgaccatata cagtcttctc gaaccctgaa taccgttatc ggtttcagca ttaccgttat
     6301 aactgttacc cattatacct gtttcggggt ctgtgtagcg ttttttggca ggaccgaaag
     6361 tcaacaggtt attaccggtt acataaacac gcaggttttc taccagggcc ttgcgggtaa
     6421 ggctcttagg cagcgtatag cctaatgtca ggtttctcag acgccagtag tggttgtcga
     6481 atacgaagtt atctgcatat tttaccgtcg cgccatactg gttgtacgac caacgtggga
     6541 taagcacatc cgcatcgccc ggctgacgcc atctgtcctc aaccaactcc tgtatcacac
     6601 cgacacccgg acggttcatg atacgttctt tatatgtata gtccgatatt ttggaaccat
     6661 aagaataata gaacatgaac gacaggtcga tccctttgaa ctggaagtta ttggtgatag
     6721 caccgaacac tttgggaatc gcggagccac agtacacaaa atcgtctgtc gttacttctt
     6781 cctgcttttc cgtacgtttc caaccgccgt taccatcgcg gatcaaccag ccgggtactc
     6841 cggtttccgg attaacaccg tcgtactggg gagcgataaa ttcatacaga gacttgcctt
     6901 cctccatctt gtaggtacag gcggtaccag aataagtgta aggacctgta ggcaaataag
     6961 tcacctcatt tttcagcgta ctcatgttgg catcgatatc ccatctgaaa tctttcgttg
     7021 taaggatatt cgcattcaat gtgatttcaa tcccgctatt acgcaggtca ccgatattca
     7081 tattataccc ggatgcacta ccaacctggg cagagagagg cagttcctta taatacaaca
     7141 agtcatggga agtacgggaa taatattcca ctgtaccgct aagtcggttg aatacggaaa
     7201 aatctaaacc gatattccat tgctgattac tttcccactt caagtccggt gtcggatagg
     7261 tagatggttt taaaccggat ttcagataca ggtcatcact ttcataagta ccctggtatc
     7321 cgtaaaggac ttcatcccct gccttaccat tcgattcacg cacgatcagc ttatcattac
     7381 cagtcgtacc gtaactacca cgcaacgaaa ggttatcaat ccatttcagg tcttccataa
     7441 aaccttcttt cgatattcgc catgaaccgc ctgtcgacca gaatgtaccc cagcgatgat
     7501 cggagctgaa acgggaagaa ccatcctcac gaagtgaagc ggacaagtaa tacttattca
     7561 agaagttata atcgacctta ccaaagaacg aaagcagaga gtatttatca cgtccgccgg
     7621 aaacaccgaa gttcttggtg gtattcgata attcatattt acccagttcc atgatacctt
     7681 caccccaacc ttgttcgtag tgggagtccc aggtatacca ctcatgtccg accagacctg
     7741 aaatcgtatg gtcaccaatc atccattcac cagacaatac attattccag gtggtggaac
     7801 gtttattgaa attataacgg ctggcataac caccgtctgc cagtatagaa ataccataag
     7861 gtgcagtctg tccgctgcca tgtacggcgg aagtatattg catggtacga taccagtaat
     7921 cgtcaatatt caaagccgaa cggaatttca ggttgaaagg aagagtaaac tctgtattta
     7981 cctgagcaga caggatatgc cccatattgt tatcgaaact gtcatcgttc ggattatccc
     8041 aataatcacc cgagttattc aggatatggg caccaaagaa gttattggta tatttaccgt
     8101 aactgtacat ccgttcccct gttttttcag aaacgaccca accggtatta tcttcattac
     8161 gtaaccaggg tgaagacaaa gtcgtcgtaa agttagccgc acggctggca ccaccggaaa
     8221 ggttctggcg atgacgcgaa taagaaaggc taccggccac tttccaccaa tcgaacaact
     8281 ctgtactcag gttggtacgg aaagaataac gtttataata ctgccggtta ccatatccct
     8341 ggtcgtccag ataaccgccg gagaagaaat aggctgtttt tccaccattg gcctgaccac
     8401 ttatatccac actataatcc tggcgcagtt tacgggagaa gatagctttg tagacatccc
     8461 aatcatcttc atcccagaca tattccagat taggattcat gtaaggattc ccattgccgt
     8521 catgcaatac gtaattttca ttgatatgtc tgaacggagt gacataaatc agattaccat
     8581 tcgaatcttt tgtagccttt acctgtttgg tcaatgcctg cgacgaagca taatcgcccg
     8641 cctgttgcat attcatgccg tcataaagaa gggcatcata atacaaggca taccaggtat
     8701 tttccagctg ctggtacgga tcggcttttt tcggattctt gacagcatta tccgaagtac
     8761 cccaacctcc gcggaagtta atacgcggtt tttctgattt accccgcttg gttgtaatca
     8821 ttacgacgcc gtttgctgca cgcgaaccgt agagcgaagt ggccgccgca tccttcagca
     8881 ccgtcatcga ttctatgtcc gtaggattga tctgattcag ttttccatcg taaggcatcc
     8941 cgtccacaat atataacgga tcggcctttc cggacatgga agcaatacca cggatctcca
     9001 cacgggcatc agctccgggg ttaccctgta cattcacaac attcacaccg gcactcatcc
     9061 cctgcaatgc ttccgcaaag ccggagccca tgatcttttc gagtttttca gcttttacaa
     9121 cggaggccga tccggtgaag gttgatttct tagccgttcc ataggctacg acaacgactt
     9181 catccaggtc ctgtgtcgca tcacttaatt ttacatttaa aatagattgt ccgttccaag
     9241 tgatctcctg agtggccagg ccgacaaagg aaataacaat aaccgctccc cgccgaacat
     9301 tatccagcgt aaactttcca tcgatatcgg ttatcgtacc gatagtggtt cctttcacta
     9361 caacagaagc tccggcgaca ggtcccatct ggtcctctac caggccggtt accttattac
     9421 cctgttgtac taccatcgtt tccggacctg taggattggc agcaatcgca cctgccgcac
     9481 ctaataatac agaaatcatt agtgatctaa ttagttttga gttggtccac atagctaaat
     9541 tcaagtcttt aattaaataa aattaatcac aatagcgttc atttcattag aggttacact
     9601 tttctaagat aaaagtgact ggcatacatt tcaataaaat aaagttaact aaaacaaaga
     9661 tatactgatc attacacaca acatccttct atatttccac tctacaaact acagtatctc
     9721 catcagcaaa tataacttat cattatttaa tacaagcata attatgtata tttattgctc
     9781 taataaatat attttaacca ccatttaatt gattttttta tctaaaatcc acattcaaac
     9841 aatgacatac atattgggat gaaaaatcaa taacagttgc aatcaaaaac attttttaac
     9901 cattaacgca ttacataaac cataaaaaaa cggcaacccg aaaagccgga ttgccgtttt
     9961 tatatcacaa aatgtttaac tattaatgta tcaccattta ttagttgttt tcaggacgaa
    10021 gtttacgaac aacagcacct gcacgccaca tttcactttc gcgaagagca gccagttctt
    10081 tttccagacc ttcacgatag tcaggcttgc tgtttgtgtc gatagaacgc tgtgcttcgt
    10141 taccgcaggc aacttcgcta tacaacttct ggaacaccgg ttttgtagca tcgtggaacg
    10201 ggcccatcca gtccaaagca ccacgctgtg cagttgttga acagtttgca tacatccagt
    10261 ccataccgtt ttctgcgaac aacggcatca atgactgagt cagttcttct actgtttcat
    10321 tgaatgcttc agaaggttcg tgaccgtttt cacgcaaagt ttcgtactga gccaacagta
    10381 atccctggat agctcccatc aaagtaccac gttcgccggt caggtcagaa taaacttctt
    10441 tcttgaatgt tgtttcaaac aagtaaccag aaccaacacc gatacccagt gcaatcacgc
    10501 gatcccatgc tttgcctgtt gcatcctgga agattgcgta gcttgagttc agaccacgac
    10561 cctgcaagaa catacggcgc agtgaagtac ctgaaccttt cggagcaacc aggattacgt
    10621 ctacatcagc aggagggatg atgtttgtac gttctttgta agtgataccg aatccgtgag
    10681 agaaatacaa agccttaccc ggagtcaggt attttttgat gcgcggccaa acttcaatct
    10741 gagcagcatc tgaaagcaga tactggatga tagttgcttt ttcgcatgct tcttcgatat
    10801 cgaacagtgt ttcgcccggt acccaaccgt cagcaacggc cttttcccag gtcttaccac
    10861 ctttacgttg tcctacaatt acgttaaaac cgttgtcgcg caggttcagg ctctggccag
    10921 gaccttgtac gccgtaacct attacagcga ttgtttcgtc tttcaatact tctcttgcct
    10981 tttccaacgg aaattcttcg cgggttacta cgttttcgtc aacgccgcca aaattcatta
    11041 ctgccatttt ctttttacta ttaaaatgta tataaaataa tttgtttttc agatccaggt
    11101 aacggcagcg cggctgatgg ctttgccgtc gttacagatt gccatattat atttatcgag
    11161 ggatacttcc tggttatgga gagtcagctc catcccatac tttccttcgg actgataagc
    11221 tatttcgaaa cggcttatct ctttttctcg gaacagactg atatcgaaca agtcgagcag
    11281 gtgttccatg tatttgatac tgttcaggtg gccgtttacg tccaggtcac tatacttcac
    11341 acggtaaggt tcgccggaag tgttgttttc caccggagca attttacccg gtttttcaat
    11401 cggacaggga cggtcggtga tataagcact caggccctcc acatcgagca aggtcgggcg
    11461 gcgggtttcc atatcgatag ccgcccagat agagcgggca aagccaaagg tcttgccttc
    11521 gccgttcacc agttcaaagc aacggctggt aaacaactta ccgacctcat ccacccaggt
    11581 atataaagtt acggattcag acatggcagg ataagaagtc atctcgatag ccagacggga
    11641 aagaacccag gcggtatgcc tttcggtcat atcgttatat ccgaatccac ggtcggcggc
    11701 atggcaagaa gcagcatgca acaaataagt tccgatcata gggattgtaa tacgtccccg
    11761 gaagtccgtc agataagact ctgttacgaa atgaaattct cctactttgt tcttctccat
    11821 aatttacttt atttacaaaa tgtttcctta ttattctcag acatgttttt cctgcaactt
    11881 cttttccatt gcagataaca tgtcgctcag acgttctacc ttactcttcg ttatagcaac
    11941 gcgtccggaa cggataaatt gcaggacacc gatcgtctca ctcaattctt taaacaaagc
    12001 ctgtgtctca tcataatgac cactcttttc caacaccaca caatcctcat tcatttcaag
    12061 gatacgggca ttgtacttac ggatcagatc ctcaaccgtc cccatcttga taaagagttc
    12121 ggtactcagt ttataaagag cgatttcctg gtaaaccagg tcttcatccg tattataata
    12181 ggctttcagg atatccacac gcttgtcgat ctgttttacg accttgtcga tcgtatcctc
    12241 gtcggcaaag gtagtaattg taaacttatg tattcccttt atagcagagg gagaaacaga
    12301 aagcgtctca atgttcagtt gccggcgcgt aaagataaca gttatctgat tcagaagacc
    12361 aacagtgttt tccgaaaaga taataacggt atataattgt tttgtattca tagtttctcc
    12421 tccttactta tcacccaaaa tcatgtttgt cacgcttcct ccggccggaa ccatcggata
    12481 taccatacca caagtttcca cattggcaac caacatatag gcaccatcgt gattcaacat
    12541 ttcagcaatc gcctcatcca agtcttcccg tttatctacc gcacgggaag caataccaaa
    12601 agccttggct atcgctacaa aatccggatt cttcatgatg gtattcgaat accgttcgtt
    12661 gaagaacagc tcctgccact ggcgtaccat tcccaggaaa ttgttgttaa gaacgatgat
    12721 ctttacattc agattttcct gcatgatagt tcccaactcc tggatagtca tctggatacc
    12781 accgtcgccg gtaaagaaac agaccgtacg gtcaggcgct cccagcttcg ctccaatggc
    12841 ggcgggaagg ccaaagccca tcgttcccaa acctcctgaa gtaactacgc tgcgtgtttg
    12901 tttatatttg aaatagcgaa cacccatcat ctggttctga cctacatccg taaccagaat
    12961 cgcatcatta tcggttgctt cggaaacctt acggactact tcgcccattt tcagttggcc
    13021 ttcggtagga tagagttctt tttctattac cttattatat tcctcttttt catccggttc
    13081 gaattcagca ttccattccg gacgcttccg ttcttccagt aaagccgtaa tcatcggaat
    13141 cgtatgcttg gcatttccca gcactttcac gtcgaccggc acattctttc cgatctccga
    13201 attgtcgata tccaggtgga taatctttgc ctgcttggca taagtcttca ggtcgccggt
    13261 tacgcgatca tcgaaacgca taccgatagc aatcagcacg tcacattcgt ttgtcttgcg
    13321 gttcggtccg acatttccat gcatccccaa cataccttta tttaatggga agtccgaagg
    13381 taatgcagac aagcccaata cggtagaacc ggctggtata tcgtttttca acaagaattc
    13441 tttcagttct tcttcagctc ctcccaggat aaccccctgc cctaccagac agaatggctt
    13501 tttggcatta tttatcaatg aagcagccgc ctcgatacgt tcctccctga tatccggttc
    13561 aggttggtaa ctacgaacat aatccacttt ctgatactca taatctacca aacccacctg
    13621 tgcatctttc gccaaatcca gtaccacagg tcccgggcga ccggtcgatg cgatatagaa
    13681 agcacgggaa acggcccaag caatttcttc cgggcggcgt atctggtaag cccatttggt
    13741 aatcggttgt gtgataccga tcacatcaac ttcctggaaa gcatctgttc caagcagcgg
    13801 agacggaacc tggccggcaa tcaccaccat cggtgtactg tccatcagcg catcggcaat
    13861 accagtgatg gtattggttg ccccgggacc cgaagtaacc accgttactc ccacttttcc
    13921 ggaaacacgg gcatatccct gtgcagcatg tgttgcacct tgttcgtggc gcaccagaat
    13981 atgttttaac tgatctctgt aatcgtataa actatcgtaa attggtatcg cctgcccacc
    14041 cggataaccg aagatagtat ctactccttc agcgatcagc gctttcagca aagcttccga
    14101 accggttatc ttttgtttgt ccatctctaa aatatagtat ttggtgttta ttaatcttct
    14161 actattcgta caccgccctt atcggccgaa gcaaccatct ttgcatatgc tttcagtgct
    14221 ttcgataccg tacgttggcg gaaaggaggt gtaaaggctt ttgttccgcg ggcttcttcc
    14281 gcttcacggc gtttggccag ttcttcgtct gtcaccttta catgtatggt tctttcggga
    14341 atattaattt cgataatatc gccgtctttc actaagccaa tcgctccgcc tgcagccgct
    14401 tcgggagaaa tatgtccgat tgacaaaccc gatgttccac cgctgaagcg tccgtctgtg
    14461 attaacgcac attctttacc cagatgttta ctctttatat aagaggtagg atacaacatt
    14521 tcctgcatac ccggaccacc cttaggacct tcataggtga taacgacgac atcgccggag
    14581 acgacttgat ctttcaggat accttcgcaa gcggcatcct gcgaatcgaa tactttggca
    14641 gggccggcaa aacggaagat actttcatct accccggctg ttttaaccac acaaccgtcc
    14701 tgtgcaatat ttccatacag aacagccaga ccgccgtctt tcacataagc atgttccaca
    14761 tcgcggatac atccggttgc acggtcggta tccagttctt tataataact ttcctgcgat
    14821 ccgagcacca gattgaaacg gtgggccgga gcacttttat aaatattgat tgcttcttcc
    14881 gttacattta cagaggtaat gcagtattgg tcgatagcct cattcaaagt cagaccatcc
    14941 gcacgtttca cggaaccgtc caccagaccg gcttttacca gctcattcat aataccgata
    15001 atacctccgg cacggttcac atcttccaca tgataagaac aactcggagc cactttacag
    15061 ataaccggtg ttttgcgtga aagcatatcg atgtctttca ttgtaaaatc gacttccgct
    15121 tcatgagcca cggccaacag gtgaaggact gtattcgtcg atccccccat ggcaatatcc
    15181 agcgacatag cattcagaaa ggcctgacgg gtggcaatac tgcgaggcaa tacggaatca
    15241 tcgccgtcac gataatattt aaaggcatta tcaacaatca tcttcgcggc ttttttgaac
    15301 aggcgggtac ggttggcatg tgttgcaaca actgttccgt tgccgggaag agccaatcca
    15361 atcgcttcgt tcagacagtt catagagtta gccgtgaaca taccagaaca gcaaccgcag
    15421 gtcgggcaag cggaacgttc caccttttct acttgttcat cgctgataga atcgtcagcc
    15481 gcttcaatca tggcgtcgat caaatcgagt gcacgtccgt ccagattacc ggcttccatc
    15541 ggaccgccgg atacaaagat tgtcggaata ttcagacgca tactggccat cagcataccc
    15601 ggagtaatct tgtcgcagtt actgatacaa accattgcat cagccttatg cgcattcacc
    15661 atatattcca cactgtcagc aatgatgtcg cgggaaggca gagaataaag cattccgtcg
    15721 tgtcccatag caataccgtc atcaatagcg atcgtattaa attctgcggc aaagcaaccg
    15781 agcttttcga tttccgcttt tacctgctgt ccgatctcgt gtagatgcac atggcccggt
    15841 acaaactggg taaatgaatt cacaatggca atgatcggtt taccgaactg ttcttctttc
    15901 atgccgttgg cacgccataa tgcacgggct ccggccatac gtctgccttc tgtgctatag
    15961 gagcttctta acggattctt catcatatct gtttttatct tttagtcaat aaaaaagccc
    16021 ttctctatat ggagaaaggc ttaagaaata tcttttacga cttcacaact tcttacacac
    16081 ctttctcctt acctactaat gactagaagg
//
