LOCUS       gnlProkkaFMEFAMOC_63   12448 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FMEFAMOC_63.
ACCESSION   gnlProkkaFMEFAMOC_63
VERSION     gnlProkkaFMEFAMOC_63
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 04:39:08
            Original ID  :: gnl|Prokka|FMEFAMOC_63
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12448
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12448
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2100:2448]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2101..2448
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12448
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12448
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..377
                     /locus_tag="ctg63_1"
                     /transl_table=11
                     /translation="MMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRKTTDFLEK
                     ATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAPQTDATAP
                     AESAPATEASATETPAPAAE"
     CDS             668..2056
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg63_2"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             2101..2448
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_3"
                     /sec_met_domain="PF05402 (E-value: 1.7e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 6.4e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(2438..2725)
                     /locus_tag="ctg63_4"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(2747..3811)
                     /locus_tag="ctg63_5"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(3885..5396)
                     /locus_tag="ctg63_6"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             complement(5862..6695)
                     /locus_tag="ctg63_7"
                     /transl_table=11
                     /translation="MTTKKLTGILSLFLCIICLVSCNDNDDNFSPITLEYEDPQIKFDN
                     ESRSYTLTPFSKETTPLFIKGGDGTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKI
                     EDSSNNMYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFT
                     FMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNG
                     KVIDTFYITKNFLPLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             6968..7192
                     /locus_tag="ctg63_8"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             7385..8929
                     /locus_tag="ctg63_9"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHILHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             8971..9507
                     /locus_tag="ctg63_10"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             9541..10110
                     /locus_tag="ctg63_11"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             10123..11289
                     /locus_tag="ctg63_12"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             11313..12098
                     /locus_tag="ctg63_13"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQTPEELVIPVQTHEANCLLIGDAYLSASSQQRQEMLHGVDALITREL
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVIA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
ORIGIN
        1 tcttaatggt gattgcagcc ttgctgatgt gcttcatcgt gctgattcag aattcaaaag
       61 gaggcggact tgcttctggt ttttcttcat caaacgctat catgggcgtg cgcaagacta
      121 cagattttct ggaaaaagca acttggggtc tggctatctt catggttgtg atgagcgttg
      181 ctactgctta cgttgttcct tcttcttctg cggctaaaga tgtattgttg gaacaagcac
      241 agaaagaaca acaaaccaac ccgtataata tgcctaccgg tactgctgct cctcagacag
      301 atgctactgc tcctgcagag tctgcaccag caacggaagc ttcggctact gaaactcctg
      361 ctcctgcagc agaataattc agtgacagga tattcggttt aaacttattg agtgaacggg
      421 ctttttgacc cgttctcttc attataggcg cgaattacgc gaattacaag agattctaat
      481 agaatcgtgt aatacgtgta gttcgcgcct gtctttatta ttgggcccgg tctgctcttc
      541 ttcatacagg aatatccggt cagatgtcct ttttcttata aaatgttctc cttttttagt
      601 aaaacaaatg ataattagtt aactttgttg cccgttacga gattattaac tccttttaaa
      661 tattacaatg acagaacaat tgaaacaaaa gctgaatgac tccgcagtgc tgcgttggag
      721 tgttctagca ttagtcgctt ttaccatgtt gtgcggctac ttcctcacag acgttatgtc
      781 tcctctgaaa cccatgcttg aaaaagaact tctctgggac agtttagatt acggtttttt
      841 caccagtgct tatggctggt ttaatgtatt cctgctgatg ctcatctttg gtggtatcat
      901 tctggataag atgggagtac gcttcaccgg aatgggtgcc tgtttattga tggtgttcgg
      961 ttgtggattg aaatattatg ctattactac tactttcccg gaaggtgcga tgcttttcgg
     1021 attcaagatg caagtcacat tggctgcatt gggttatgct attttcggtg taggagtcga
     1081 aattgcgggt atcaccgttt cgaagattat cgtgaagtgg tttaaaggca aagagatggc
     1141 tctcgctatg ggactggaaa tggcgaccgc gcgtattgga acgactttgg ccatggtgct
     1201 taccgttcct ttggcagact tcttcgggtc tacggatgag agcggcgtat tccataccaa
     1261 tattcccgct cctattctgt tctgtctcgt catgttgtgc gtaggtacca tcgcattctt
     1321 catctatact ttctacgata agaaactgga tgcttcactg gatgcggaag gactggaacc
     1381 ggaagaacct ttccgcatga aagacattgt ctatatcatt accaacaaag gattctggct
     1441 gatcgcatta ctgtgcgtat tgttctattc ggctgtattc cccttcatca agtatgcggc
     1501 cgatttgatg gtacagaagt acaatgttga tccgaaactt gcgggaacga ttcccggatt
     1561 gctgccgatt ggcgcgatca tcctgacacc gttgttcggt tcattatatg accgtatcgg
     1621 taagggagcc acgctgatgg tgatcgggtc ggtgatgctg attttcgtac acacgatgtt
     1681 cgctcttcct attctgaata tatggtggtt tgcaacggtg atcatgatta ttctgggatt
     1741 tgctttctca ttggttcctt cggcaatgtg gccttcggtt ccgaagatta ttccggagaa
     1801 acagttggga acggcttatg cgttgatctt ttgggtacag aactggggat tgatgggcgt
     1861 gcctttgctg atcggatggg tgttgaattc ttattgcaaa ggtccggttg tagatggtgc
     1921 acagacttat gattatactt tgccgatggc tatttttgct atgttcggtg tacttgccct
     1981 gattgttgcc ttgatgctga aagtggaaaa caagaagaaa ggctacggac tggaagaagc
     2041 aaatattcag aaataatcac agtatatatt ctatctgaaa agatataaaa gagaaaagat
     2101 atggctacga aagagaaaat aaacctcctg gaggtgatcc cttgtcgtaa cgaacatatt
     2161 aaagctgaac aggaagggga gactattgtg ctctccttcc ctcgttttaa acgttcgtgg
     2221 atgagtcgtt atttattgcc gaaaggaatg tccaaagata ttcatgtgcg tctggaagaa
     2281 cacggtacgg ctgtatggaa cctgatagac gggcagcgga cggttcgtga gattatagaa
     2341 aaactcgcag accactttca atatgaagca ggctacgagt ctcgtgtatc tacctatctt
     2401 tcccaattac agaaagacgg atttattaaa tggataatta tccattaaaa aagattgccc
     2461 acaggaggac agcacatcct atcagtacgc ccataatgat gagcgttccc catacgaaat
     2521 agctgttatc tttttctttt ttcttttccg aatccttgat gatgcgttcc atctcttccg
     2581 gagtcgtatc cggcagaaga taagggtcgt tgtttcttct aagtcgccct aacttgtcat
     2641 ttctccgttc acggcgtaag cgggaggctt ctttgccgtc tttcagccga cgtatcatgt
     2701 cgagcatatg tccttcgcca cccatcgttt tgttttttta gaggttttat ttgctttctt
     2761 ctctatctac tttcagtagt ccaccggtca ccggatcaaa gtaaactttg atggtcgagt
     2821 tcttgttgaa taataccgga gcaaggtatt ctatgatacc gaactgagta acaggtattt
     2881 ctccttcata caatttcttt ttgccgtccg tcagcgtcac cattgcctgt cccggtacgt
     2941 tataagcaat gccttccatc tctttcttct ttttcccgtc ctcttgcgga atcttcaccg
     3001 ttttcaggtc tttcagactg atgtagaatg gagtgcctgc caaatcgttg ttggcaacta
     3061 tacccagctt ctttgaaaag cggaaagcta cctcattgtc gaattcctta tccggagtga
     3121 ggcggacagt aaatgtcttt tcttctttat tgcggactcc cgaaaacatc tcggtcatgg
     3181 cttcttcctg aagattcagg ttgtcgagca tgattttgag ctgtgcgccg tccgaaggca
     3241 tattatctgc ttgtccgcgc aataatgcgt ttttactttc gcggatatta tagatttcct
     3301 ttgctaccag ttcggccatc ttggcggttg aacttgccat cagaatttct tctgtgagaa
     3361 agtcgcgggg attggctttt cgttggggag caacggcatt gtttgctgca ttctttgcat
     3421 tgttactgct gtaggggaca ttgattgatt tgataagacc ctcttcagtc agttccataa
     3481 gaggagctac ggttttgtct ttcagtttga cgaaataagt agcttcgctg tttggtacac
     3541 ctacaggttt cactttgaca ctgttcagtt cccagtattc ttcgggttcg gcagagacgt
     3601 tggtcagtct caggtagcgg tcggcgtatt tgctgaattc acccggctta tagttgactt
     3661 tgtttgcttt tatttctatt tctatctggg ttttggggag ggcgtacact actccgtagt
     3721 cttttcctcg cgtcactcct gtcagcactt cggtctgcgc ataggcggaa gttgccatta
     3781 gtagtcctgt tgctatgatt aactttttca tattcggttc tttttagctg attttgaaaa
     3841 acaaagttaa tgaagttatt gaataaaccg taagttctta acttttattc gcttacaagt
     3901 cgccatgccg tcggcagaca agtcacgata tcacttgcga ttaatccgat catgccctgt
     3961 tttttctggg cgatgtctcc ggccaatccg tgaatgtaag taccgatctt tgcggcgtct
     4021 tcggcgggat agccttgcgc aaggagtgca aggattactc ctgtcagtac atctccgctg
     4081 cctcctgttg ccataccggg attaccggtc tggttgaagt aacatttgcc ttcgggggtg
     4141 ataatggcgg aataagctcc cttcagaatg atatgtactt tggcagtgtg cgccagttcg
     4201 caggctttca tcagtcgttc gtatgagtcc tgacatttgc cgaccaggcg ttccagctct
     4261 ttcgggtgag gggtgaggat ggaacctttc ggcagatggg tgagcgtatg ccggtgattg
     4321 gccagaatat tgagtgcgtc ggcatccagt accgtcggag tctgacaatg ttccagttgt
     4381 tctatcaggg cggcttccgt ttcttcgttg cgaccgagtc ccggaccgat gccgacagct
     4441 tggtaatcgt ccgtatcggt aggtacggca aagcatgttt cgctgacatc tgtttctacc
     4501 atggcttcgg gggcggacgt ttgcagaata tcgttgttgc ataacggcgc gtgtaccgtc
     4561 agcagaccta ctcccgatcg caaacaggca cgggcggcca gtaccgatgc acctgccatt
     4621 ccttttgagc cggctatcag cagggcatgt ccgaagtttc ctttatgggc gaattgttgg
     4681 cgtggtttga tcagtgaacg gatttcttcg atttccagca tttcgtagtt tgtttcagtc
     4741 tcttcgattc cttcttcgct cagctggatg tccaataact cccattcgcc aacaaattct
     4801 gtattttcgg caaagaggaa ggccagttta ggaagttgca ggctgaaagt gacgtccgca
     4861 cggataatat tgctttttac attgaatgta ttttcttctc ccatcagccc ggaagggatg
     4921 tcgatggaga ctaccatggc gggagaggca ttgatatatt tcacaacggc agcgaatcct
     4981 ccgctcaatg gtttgttgag tccggaaccg aataatccgt cgatcacgag atgttccggt
     5041 gtcagtgtgg gaggtacgaa ctgggtgctg atttcatgga aagttacttc ttccatcatc
     5101 tctaccagtt ctttgttggt ctggcagtcg ggcgaaagtt cgcctttcgt gttgaagaga
     5161 tatacttcga tcttgtatcc tttttccgcc atcatgcggg cgatggcgag ggcgtctccg
     5221 ccattattgc ccggtccggc aaagatggtg acaggtgttt ccggattcca tctgttggtg
     5281 atggctttag tcagtgcctg tgcggcacgt tccattaaat ctatggatgc aatcggttca
     5341 tgttcaatgg tataggcatc taacttctta atgctgctgc ttggaaatat tttcattgcg
     5401 atattctttt agttttcgac gcacaaactt acacaaaaac tctgaattaa tcctttattc
     5461 cggttggttt tcggcttttt gggaaggaac ttcaggtatt aatacttgag ttgtcaggta
     5521 ttaatagttg atgtgtcagt tattaatagt tgagaagtca gatattaatg attgttatct
     5581 catttacttt tactctctcc ggagaacatt catggctgtt tgttaacctt cccatgcgtg
     5641 tttctactac tgtatattcc tctggttcac ctctttcacc cgcaatcgcc ttattcatca
     5701 aaggttcagg aaaagggtgg aagaggtgat tgtgataaat atgctatggg catattcttg
     5761 attagctaat agcttattgt tttttgctaa atctaatggg gagtttgctc atataataaa
     5821 tactctattc actctgctaa agaagaaaat cagtgtagct ctcattctgc tatttgaatc
     5881 agatatgcat tttccagtgc aaggtaatct tgtttgtact gtgcggttaa atctctgaca
     5941 aaacagtact gaattaacgg atgagcattc attcttgtat tgaggagtgg tagaaagttc
     6001 ttggtaatat agaaagtatc aataactttg ccattatctt ctttgattgt tatacggtaa
     6061 tactcactca atttgtattc acctttgatg ggaatggcat tttcttcatc cagcactata
     6121 tgttcttttt caaagttgcc tgttttcatg ttattatctg aataatacaa atctactgtt
     6181 cctttgctgt cttccgcatt cataaaagta aatacatatt tattaatcgg atatgaattg
     6241 cccactttgt tcattaactc agtgtgttct tcagatgtaa gctcgtctcc cttcacaatg
     6301 acttttgctg taaacgcctt atgagtaaga gtacgatatt ttacaacgac agacagtata
     6361 tacatattat tcgaactgtc ttctatcttg atggatgcgc gtcctatttc ctttgccttc
     6421 aatgttaaac ttccgttgtg gtagtttact tgtaccactt tctcattctc attggtcact
     6481 ttgtaagttc cgtctccacc cttgatgaag agtggtgtcg tttctttgct gaacggagtc
     6541 agtgtgtaag aacggctctc gttgtcgaac ttaatttgag gatcttcata ttccagagtg
     6601 attggagaaa agttgtcatc attgtcatta cagctcacga ggcaaataat acaaaggaat
     6661 aacgaaagta ttcctgttag ttttttggta gtcatgctaa ttaaagtttt aaatgtgcga
     6721 tattagttta gttctcgtct gcaaacttat gaaaaagaat tgaactgttt ctttatttgt
     6781 gctatttttt agcagagatc ggcataaatg attagaatgt aactaataat agcagctaat
     6841 gctttgatta tttgcttttt tcgaaaaaaa tgatatcttt gtagtgcagt aatgtgcttt
     6901 acgttattct cctgtgctca caatgtttag attataaata taaattgttt aatcttctaa
     6961 agtttgcatg atggaaaaga aaagaattgg ctcaaatgcc gggaaagtat ggcgcatctt
     7021 aaatgaaaag ggcgaacagt ctatgttcac tttgtgccat gagttaggtt tgacgttcga
     7081 ggatgtagcg attgctatcg gttggctggc aagggaaaac aaaatcctgc ttagaaaaaa
     7141 agaaggaatg ctctatgcca gtattgagaa tgttgaattt acctttggat aaatggggac
     7201 tgacccacat ttaaggagaa tatccacttg attatttaca ctgttgaaaa cataataagg
     7261 tgggtaactg agacttcttg cacgccatcc tgtatttttc tattccataa gaatcttctt
     7321 ttttgaggca tttaatctac tttttagtac ctttgcgccc cataaactac taaacacata
     7381 attcatgagt tcattgaaag ggcacccgaa aggcctttac ctaattttcg caacgagcac
     7441 ggcagaacgt ttcagttact acggtatgcg tgctatcttt atcctctttc tgacgcaggc
     7501 attgcttttt gataaagaag cggcggcctc tatctacggt agctacaccg gactggtcta
     7561 tctgactccg ttgatcggcg gatacattgc cgataaatat tggggtatcc gtcgttcggt
     7621 attttgggga gcggtgatga tggcagtcgg tcagttcctg atgtttatga gtgcctcttc
     7681 actgaacaat acagaccttg cccactggct gatgtatggc gggctcggat tcatgatttt
     7741 aggtaacggt tgctttaagc ctaccgtttc ttcgctcgtc gggcaattat atgaacccgg
     7801 ggacaaacgg ttggatgctg catacaccat tttctatatg ggtgttaatg taggttcttt
     7861 cgccgctcct ttgatttgcg gtttcttggg agacacaggg aatccgcagg actttaaatg
     7921 gggattcctc gcatccggaa tcatgacgct gttcactgtt gtcctctttg aaactcagaa
     7981 gaataaatac cttttctctc cttccggtga accgattggt atcgtccccg acgccagacg
     8041 tgaaaaaaag gaggataaag ccgaacatat tttacatccg aagatggaca aacgtaccaa
     8101 agtacgtaat atcatcatca ttactgccct tacggttgcc ttaatagcct tttttagcta
     8161 tgcctttagc gatgactgga ttagtgtggg tatctttacg gcttgtattg tctttccagt
     8221 gctcattctg ctggatggtt cattgaccaa agtagaacgt agccgtattt tcgtaatcta
     8281 tatcgtagct ttcttcgtca ttttcttctg ggcagcttac gagcaggcag gagcttctct
     8341 gacattattc gcttccgaac agactgaccg cagcattttc ggctgggaga tgccggcttc
     8401 gtggttccag tcattcaatc cgctttttgt agtgatcctt gcctatatta tgcccggtat
     8461 atggggcttt ctgaataagc gaaacatgga accggcttcc cctaccaaac aggcaatcgg
     8521 tctgttgctg ctttctcttg gttatctctt catctgtttt ggagtgaaag atgctattcc
     8581 aggagtaaag gtgagcatga tctggctgac agggctttac tttattcata caatgggaga
     8641 aatcgctctg tcacctatcg ggctttctat ggttaataag ttgagtccgt tacgtttcgc
     8701 ctccttgatg atggggatct ggtatctttc taccgccacc gcaaataaat ttgcaggtat
     8761 gctgagcggc ctctatcccg aagacggaaa agtgaaatca atccttggtt atcagatcgc
     8821 taccatgtac gacttcttca tgctgttcgt cattatgtcc ggtgttgcct cactgattct
     8881 gttccttctc tcgaagaaat tacagaagat gatgcacggg gtagaataaa aaattgtatt
     8941 tttgcgacaa cttttttaaa atgaccggtt atggatacca tacagataaa agacaagcaa
     9001 tttactgttt ccattaagga acaggatatt caaaaagaag tgattcgcgt agcgaacgaa
     9061 atcaatcgtg atttggcagg taagaatccg ctcttcctca gtgtgttgaa cggctcgttc
     9121 atgtttaccg ccgacttgct gaagcatatt acgattccgt gcgaaatttc attcgtgaag
     9181 ttggcatctt atcagggggt gacttccacc ggagtaatta aagaagtgat cgggctgaat
     9241 gaagacattg ccggacgtac ggtagtgatc gtagaagata ttgtagatac cggactgacg
     9301 atgcagcgtc tgctggatac actgggcaca cgcaaccccg aagcgattca tatcgcctct
     9361 ttgctggtga aaccggaaaa gctgaaggtc aatctgaaca tagaatacgt agcgatggaa
     9421 ataccgaatg attttatcgt tggctacgga ttggattatg atggtttcgg acgcaattat
     9481 cccgatattt atactgtagt agattaaatt caaatacaaa ttaattttta ggttaaaaag
     9541 atgttgaaca ttgtaatttt cggtgctccg ggttcaggaa aaggaacgca gagcgaacgt
     9601 attgtagaaa agtatggaat caaccacatc tcgacaggag atgtattgcg tgcagaaatc
     9661 aagaacggca cggaactggg caaaactgct aaaggttaca tcgaccaggg acagttgatt
     9721 ccggatgaat tgatgattga tattctggca agcgtattcg atagcttcaa agacagcaaa
     9781 ggtgtaattt tcgacggttt cccaagaaca attgcacagg cggaagcatt aaagaagatg
     9841 ttggcggaaa gaggacagga tgtttctgta atgttggatc tcgaagttcc ggaagatgaa
     9901 ctgatggtac gtctgatcaa acgtggcaaa gactccggtc gtgccgacga caacgaagaa
     9961 acaatcaaaa aacgtctgca tgtatatcat tcacagacat ctccgctgat cgactggtac
    10021 aagaacgaaa agaaatacca gcatatcaac ggtctgggta ctatggatgg tatcttcgct
    10081 gatatctgcg aagcagtaga caaattgtaa taaataaaaa atatggctga atcgaatttt
    10141 gttgattacg taaagatata ctgtcgctca ggcaagggcg gaagaggctc tacgcacatg
    10201 aggcgcgaga aatattgtcc taacggaggt cccgatgggg gcgatggtgg aagaggaggc
    10261 catattatct tgcgcggtaa ccgtaattac tggacattgc ttcacttgaa gtatgaccgt
    10321 catgcgatgg caggtcatgg cgaatcgggc agcaagaacc gtagtttcgg aaaagacggt
    10381 gcggataaag tgatcgaagt accctgcgga acggtagtgt ataacgccga aaccggagaa
    10441 tacctttgcg atgtgacgga cgacggacag gaagtgatct tgctgaaagg cggtcgtggc
    10501 ggtcagggca acagtcattt caagacggct acccgtcagg ctccgcgctt tgcgcagccg
    10561 ggcgaaccga tgcaggaaat gacggtgatc atggagctga aactgttggc agatgtagga
    10621 ctggtaggtt tcccgaatgc gggaaagtct acgttgcttt ctgccatttc ggctgcgaaa
    10681 ccgaagattg ccgattaccc gtttacgaca ctcgaaccga atctgggaat tgtttcctat
    10741 cgcgatggaa agtcattcgt gatggcggac ataccgggca tcatcgaggg agccagtcag
    10801 ggaaaaggat tgggactgcg gtttctgcgt catatcgagc gtaactcgtt gctgttgttc
    10861 atggttccgg cagatagcga tgatatccgc aaggagtatg aagtattgct gaatgagctg
    10921 cgtacgttca atcccgaaat gctggacaaa caacgtgtgc tggctatcac gaagagcgat
    10981 atgctcgatc aggagctgat ggacgagatt gaaccgacat tgcccgaggg tgttccgcat
    11041 atattcattt cttctgtttc cggtttggga atctcagtgt tgaaagacat tctgtgggag
    11101 gaactgaaca aggaaagtaa taagatagaa gacattgttc accgtccgaa agacgtgacc
    11161 cgtctgcaac aggaactcaa ggacatgggc gaggatgaag aactcgacta tgaatatgag
    11221 gaagacgctg acgacgacga tgatgatctc gactacgaat acgaagaaga ggattgggaa
    11281 gaaaaatgat ttcaatcaca agagataaaa gaatgttggg gtatgagtcg ttaagctcat
    11341 actccaacat ttctcatttt gtaactaccc ggcagggagg gtgcagcgaa ggaaattatg
    11401 cgtcattcaa ctgtacgccc tacagtggag acgaggcgga aaaggtccgg cggaatcaaa
    11461 cgcttctgat ggaaggaatg tcgcagacac ccgaagaact ggtgattcct gtgcagactc
    11521 atgaggcgaa ttgcctgctg atcggggatg cttatttatc ggcttcgtct caacaacgac
    11581 aggagatgct gcacggagtg gatgctttga ttacccgcga gttgggatat tgcctttgca
    11641 tttctactgc agattgtgtt cctgtgttga tatatgataa gaaacatagt gccatagctg
    11701 ccattcatgc cggatggaga gggacggtag catacatcgt gcgtgatact ttgttgcgga
    11761 tggagaagga gtttggcaca agtggagaag atgtgatagc ctgtatcggt ccgagtatct
    11821 cattggcttc ttttgaagtg ggtgaggaag tgtacgaagc atttcagaag aatggttttg
    11881 atatgcctcg tatttctatc aggaaagagg aaaccggaaa acatcatatc gacttgtggg
    11941 aagcgaaccg gatgcaaatc cttgctttcg gtgtgccgtc cggacaagtg gagcttgccc
    12001 ggatatgtac gtatattcat cacgacgagt ttttctcggc aaggcgtttg ggcattaagt
    12061 ccggacggat tctgtcgggg atcatgattc ataaataata gacttgaacg taagttgata
    12121 taaacttgaa taaaagtatg tttgaaataa aagtatctca ggaaataaag aacgcctgcc
    12181 ctgtttttgc cggagcagcc gtatatgcag cagtgaagaa tactgcttat tgcgatggac
    12241 tttggaaaga aataaatatt ttcacagaag acttgactac caccacccaa atggcagaca
    12301 ttaagttgca acctgtgatt gctgctaccc gtgaggctta taagcgttgc ggaaaagatc
    12361 cggggcgtta tcgtccgtcg gcagaagcgc tgcgccgtcg cctgatgcgt ggcatccctt
    12421 tgtatcagat tgatactttg gttgacct
//
