LOCUS       c00136_gnlPro..        11221 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OEFMMPJE_136.
ACCESSION   c00136_gnlPro..
VERSION     c00136_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 14:59:16
            Original ID  :: gnl|Prokka|OEFMMPJE_136
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11221
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11221
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5856:10713]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5857..10713
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..11221
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11221
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(3..1784)
                     /locus_tag="ctg136_1"
                     /transl_table=11
                     /translation="MRISLALLFAVVLQLSAENGYAQRTHVAISMNNVSVEQVLNKIEE
                     ASDYVFLYNDKTIQKNRIVSVRNKSGKILDILDDIFKGTDITYTVVDKQIILSTNKMQL
                     VQQEGQIQIKGVVKDAGGDPLIGVNVKVKDSTVGTITDINGNFTLQTRKGDILEISYVG
                     YATKTVKVQNAQVLNIVLTEDTEVLNEVVVTALGIKKEAKSLSYNVQQVSNAEITRIAD
                     ANFVNNLNGKVAGVTINSSSAGVGGSSRVVMRGTKSLNGNNNALYVVDGIPMSDMSAAS
                     TQPTDSYEGAGQSGDPISGLNPEDIESISVLSGPSAAALYGSAAANGVVMITTKKGREG
                     RTSVSISNNTTFSAPLVLPEFQNTYGQTEVGSYYSWGSKLNTPSSYDPKDFFQTGVNVT
                     NAASLSTGTDKNQTYLSLGTTNAKGIIHNNDYERYNVTVRNVAKMLKDKLTLDLSFMLS
                     SVKEQNMTSQGLYYNPLVPLYLFPAGDDFSKVQAYQRYDSERNLLTQYWPYSTSLALQN
                     PYWITEHIKIRNHKNRYMATASAKYEFADWINVTARAKMDRNNERRERMYDAGTNTLFA
                     SKYGYYSKSNIENQQIYG"
     CDS             complement(2034..2957)
                     /locus_tag="ctg136_2"
                     /transl_table=11
                     /translation="MENMNPESLLRKAQALGEDIKEMESIDVMGAYQQAQTQIKTNRRR
                     SMYNQLMRYAAFLTIPLLLSSLILGYLYWGATDTEEKYAEVMAATGSVIRYELPDHSVV
                     WLNSGSTLRYPTVFKKDNRNVELKGEAYFEVEADRKRPFYVNTPAGLSVYVYGTKFNVN
                     AYEDDNSIETVLEKGKVNVISPDGKTTVQLAPGERLLYNKVDQKLLKGKVDVYEKVAWK
                     DGKLIFRNAELGEIFKRLARHFNVDIQFNNISGKEYKYRATFRNETLPQILDYLAKSAA
                     LKWRTEEAVQQADDTFTKKKIIVDLY"
     CDS             3182..3751
                     /locus_tag="ctg136_3"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             complement(3725..4831)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg136_4"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-17, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFL
                     NEWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYI
                     GAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQT
                     EILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVE
                     LFLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIER
                     LLQSSIPVPFVITSVPDRRLGQAVTLLIEGQMEISALGTKLESVLASYYRPKYIYTVNH
                     IPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(4828..5853)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg136_5"
                     /sec_met_domain="MR_MLE_C (E-value: 3.6e-30, bitscore:
                     94.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(5857..6681)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_6"
                     /sec_met_domain="ECH_1 (E-value: 1.7e-82, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(6685..8352)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-09, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPWLDY
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(8372..9484)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg136_8"
                     /sec_met_domain="Chorismate_bind (E-value: 2.6e-58,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(9481..10713)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_9"
                     /sec_met_domain="HBT (E-value: 1.8e-17, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(10798..11160)
                     /locus_tag="ctg136_10"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
ORIGIN
        1 tcaccgtata tctgttgatt ctcgatatta ctcttggagt aataaccgta tttagaagca
       61 aacaaagtat ttgttccggc atcatacatg cgctcacggc gttcgttgtt gcggtccatt
      121 ttggcacggg ctgttacatt aatccagtca gcaaattcat attttgccga tgcagttgcc
      181 atataacggt tcttatgatt acgtatttta atatgctcgg taatccagta tggattctgt
      241 aaagccagac ttgtgctgta aggccagtac tgagtcagta aatttcgttc cgaatcatac
      301 cgctgatatg cctgtacttt ggagaaatca tctcccgcag gaaatagata aagaggtact
      361 aacgggttat aataaagtcc ctgagaggtc atattttgtt cttttacaga gctaagcata
      421 aaactcaggt caagagtcag cttatctttc agcatcttgg caacattacg gacagtgaca
      481 ttgtaacgtt cgtagtcatt attatggata atacctttgg cattggtagt acctaaagat
      541 aagtaagtct gattcttgtc agtacctgta gaaagactgg cagcatttgt tacattcaca
      601 cctgtctgaa agaagtcttt aggatcatag ctgctcggcg tattcaattt actgccccag
      661 ctgtagtaac tacccacttc tgtctgccca taagtatttt gaaattcggg caagacaaga
      721 ggagcggaga aagtcgtatt attggatatg ctgactgaag tacgtccttc cctacctttt
      781 ttagtagtaa tcatcacaac accattggca gcggcactac cgtaaagagc tgcagctgac
      841 ggtccactca aaacagagat actctctata tcctcgggat tcagaccgga aataggatca
      901 ccggactgac cggcaccttc gtatgagtcc gtaggctgtg tagaagcggc actcatatca
      961 ctcatcggga taccatcaac cacataaaga gcattgttat taccattcaa tgatttggtt
     1021 ccacgcatca ctacacgtga agagccaccg acaccagctg aagatgagtt aattgtaaca
     1081 cccgcaactt taccgttcag attattgacg aagttggcat ctgcaatgcg tgtaatctcg
     1141 gcattgctta cttgctgtac attgtatgac aaagatttag cttccttctt gatacccaat
     1201 gcagtaacaa cgacttcatt cagtacttct gtatcttctg tcagcacaat attcagaact
     1261 tgggcattct gtacctttac tgttttcgtg gcatatccca cataagaaat ttccagaata
     1321 tctcctttcc tggtctgtag cgtaaagttt ccgtttatat cggtgatagt accgaccgta
     1381 gaatctttca ctttcacatt cacaccgatc aagggatctc cgccagcatc tttcacaact
     1441 ccttttattt ggatttgtcc ttcctgctga acaagttgca ttttattagt cgataaaata
     1501 atctgcttgt caactacggt atacgtaata tcggtcccct taaaaatatc atctagaata
     1561 tccagaatct tacctgattt atttctcaca gaaacaatac gattcttctg aatcgttttg
     1621 tcattgtaaa ggaaaacata atcggaagct tcttctattt tattcagtac ctgttctaca
     1681 gatacattgt tcatagaaat ggcaacatgc gtccgttgag catagccatt ctctgcagat
     1741 agttgtaaaa cgactgcaaa aagtagtgcc agactaatcc tcataactaa aggtagtttt
     1801 agatttaaag catatttagg atataatgca ataaatgaat gatttttttt catacatttg
     1861 cggttaacta aagtttatta ctataatgaa ctgtggtttg attccggtta gcgtttgcaa
     1921 gactccttac cgcgaatctg aaaaattggg ggaagacagc tgttggtagc agctttcttc
     1981 ctttttttac gatctttgtg ttatctcata ggctattctc atttttatgg ttactaatat
     2041 aaatctacta ttatcttttt ctttgtgaat gtatcatctg cctgttgtac cgcctcctca
     2101 gttctccact tcaaggcagc agacttagcc agataatcca atatctgtgg cagtgtttca
     2161 ttacggaagg tcgcacgata tttatattct tttcccgata tattattaaa ctgaatatct
     2221 acattaaaat gccgtgccag ccgtttgaat atttcaccca actcggcatt gcggaatatc
     2281 aacttaccgt ctttccatgc caccttttca taaacatcca cttttccctt caacaatttc
     2341 tgatctacct tattataaag caatcgttct cctggagcta actgaactgt tgtttttccg
     2401 tccggtgaaa taacgtttac tttacccttt tctaataccg tttctatact attatcatct
     2461 tcgtaagcat tcacattaaa tttggttccg tacacataga cacttaaccc ggcaggagta
     2521 ttgacgtaaa aaggccgttt cctgtccgct tctacttcaa aataggcttc accttttaat
     2581 tcaacattac gattatcttt cttaaaaacg gtaggataac gtaaagtact accggagttt
     2641 aaccagacaa ccgaatggtc aggaagttcg taacgaatga ctgaacctgt agccgccatg
     2701 acttctgcat acttctcttc agtatccgtt gctccccaat ataaatatcc caaaatcaaa
     2761 gaagaaagta ataaaggtat agtcaagaat gcagcataac gcatcaactg attatacata
     2821 ctccttcttc tgtttgtctt tatttgggtc tgtgcttgtt gataggcacc cattacatca
     2881 atagactcca tttccttaat atcctctcct aatgcctgcg cttttcggag caatgattcc
     2941 ggattcatat tttccatatt ctctttcaaa atcttatctt ttaattgcaa ttacactaat
     3001 agtacaactg aggtaatcga aaagggacag gtataacata ctttttttta ttttattttt
     3061 taagctatct tattttccac agcttcatac caaaaacgaa aaaagaaaga aaattttagg
     3121 aaatgctgat tttcttatta tatatttgaa gtaaaatgaa aaactacaga atctcaaaat
     3181 aatgaaaata tctttttcca gacagactaa agaaagagct ttcaaacaac tttacgagga
     3241 ttattatgcc cctttctgcc tgtatgcaaa aagatttgta gatgataaag aagtccgcga
     3301 ggacattgtt tcggatgtat tcacctccct atgggacaag ttggataccg actctttcga
     3361 tttgcaatca gagacagcat tgggatatat aaaaatgtgt gtaaaaaaca gctgtttgaa
     3421 ctttctgaaa catcaggagt atgaatggag ttatgccgaa aatatccaaa agaaagctcc
     3481 tctatatgaa acagaaacag atagtgtata tacacttgat gagttatacc gaatgctata
     3541 cgaaacatta aataagcttc cggaaaacta tcgcaccgta tttatgaaaa gtttctttga
     3601 aggcaaaaca catgcggaaa ttgccgaaga aatgaatctc agcgtaaaat ccattaatcg
     3661 gtataaacaa aaaacaatgg aactcctgcg gaacgagttg aaagattacc tcccgctgtt
     3721 tttattattc ctgtctcccg agcaactgta agctctctgc taaaacacgg cactctttac
     3781 gattaatctt cccatttccc gtttgaggaa tatgatttac cgtataaata tatttaggac
     3841 gataataaga tgctaagact gattccaatt tagtccctag cgcacttatc tccatctgcc
     3901 cttctatcaa taaagtaaca gcctgcccca aacgccgatc cggaacggaa gtgatcacaa
     3961 acggtacagg gatagacgac tgaagtaacc tttcgatctc ttctgcctgc actttaattc
     4021 ctccgctatt gattacatta tcctttcttc ccagaatcgt aaaactaccg tccggataaa
     4081 tgcgggcaat atcatttgtc tgcagagtat catcgcaaac aagcggagca ttaatcatca
     4141 aagtattttc tgaagacaaa aacaactcta cggatgaaaa aggataataa cgatcggatg
     4201 ctgctgcgcc attcagacgg cgaagagcga tgtgagaaag ggtttccgtc atcccgtaag
     4261 ttgaataaac agcattggac agatttctga ttttttcctc taaagccttg tcaactgctc
     4321 cgcctcctat aattaaaatc tccgtttgct ttaatttctc tttctcttcg ggtatctgaa
     4381 atgtattata cacctgcaaa ggcaccatag ccgcaaacct taaaggagtg tccacatctg
     4441 ccaatggatg accggaagcc cgacgtacta taagattcaa cccggcaatc aaagaacgga
     4501 cgactaccat catcgccccg atatagcgaa ggttcataca caataatgcc gtttcaccct
     4561 gctttaaatc cagaaactca caagtcaggc gtgcactctg tatcatctga tctttgcgaa
     4621 caagcaattc tttaggtgcc cccgtagaac cggaagtatg tacagtgatc acaggatcat
     4681 cattaaacca ttcgtttaga aaaagataca agtcccatat agcagaaggg tggtttccct
     4741 caccttctgc tacaaggcta tgtatatcgc ccggagtata ttcctttccc tccagcaaca
     4801 aacgctgttt ttgtcggtcg aatatcatca tttacaaaac cacaaacaat cttttctgat
     4861 ttcaagaggc atctctacat tatctgtaaa gagtaacccg gtgcctaacc cttgcggcaa
     4921 tggattctga aaagtagcac accattgagc gatagcattc agaccgatat tagactccag
     4981 agcagaagtt atccaccaac cgatattcag tttctccgct tctgcaatcc actcctcgcc
     5041 accggctaat ccgccatgaa gagaaggttt gataataata tattgcggac ggatagccga
     5101 aagtaatctt tgcttttctt cccaggtatt atagcctatc agttcctcat ccaaagctat
     5161 cggcaaagga gattcggaag taagacgtgc catttcttcc cattgtccgg cacgaatggg
     5221 ctgttctatc gaatgtaagt ccagttcgga caagcgtttc aatttctcca tcgcatctgt
     5281 tggtgagaat gctccgttgg catctacacg caattctatt tctttagaag aatagtgaga
     5341 gcggatatgt tggagtaaag ccagttcttc ttcaaagttg atggcaccga tcttcaactt
     5401 tatacagcgg aatcccgcct ccatcttctt ctctatctga gcaagcattc tattgaagtc
     5461 acccatccag ataagcccgt ttatcggaat acctgcttcc ccacgtgaga agggtgtatc
     5521 ccacaaagcc cagcttcctt caaaaaagtg acgaatggct gtctccaagc caaaaaggat
     5581 ggaagggtac ttgcatagag cttccatgtc cagcttacct ccctgattct ctacctgccg
     5641 gcagatttta gccagcactt cctcgtaatc gggaagatca tcacagctaa gatttggcag
     5701 aggagcgcac tccccgatcc ctacccaatt gggaaattcg ggagcagtaa aatgaagata
     5761 ccagactttt cgcgttgtgt atgtgcctcg tgaagttccg gccggctgct tgaaatgaag
     5821 cacccgcgga ataatgtcta ttttgcaatc cattgtttaa gggaacttcg gatatttctt
     5881 aaagttaggt ttacgtttct ccagaaatgc attctttcct tcctgagcct catccgtcag
     5941 atagtaaagc aaggtcgcat cccctgccag ctcctgaata cctgcctggc cgtccagttc
     6001 ggcattcaat ccggctttaa tcatccgcaa ggccaacgga ctgagcagca tcatttcttc
     6061 cgcccattgc acatactcat cctccagttg ctccaatgga actactttat tcaccaatcc
     6121 catatccaac gcttcctgcg cattgtattt ccggcaaagg aaccatatct cacgtgcctt
     6181 cttctgaccg acgacacgag ccagataaga ggctccgaaa cctgcatcaa agctacctac
     6241 gcgaggaccg gtctgtccga agatcgcatt ctccgaagca atcgataaat cgcaaactac
     6301 atgaagcacg tgtccgccac caatggcaaa tccatttacg gcagcaatta ccggtttcgg
     6361 aatgctgcgg atttgtttct gtacatccag aacactcaga cggggaacac cgtccttgcc
     6421 gatatagccg ccacgccctt tcacattctg gtcaccgccc gaacagaaag ccttgtcacc
     6481 agctcccgta atcacgatca catcaatatc cgcttcttcc cggcaaatgc gcaatgcgtc
     6541 actcatttca gccgttgtag tcggagtaaa tgcatttcga tagcgttcac ggttaatggt
     6601 gatgcgggca atcccattat agtaatcaaa gaggatatct tcgtattctc tgatggttgt
     6661 ccattctctt tgtgttgaca taatctattt ttgttttagt tgatgataat aatctttcag
     6721 tatacgtgca tctttatttt tattgctgaa tacttccatc agaaccggtt gttccatggc
     6781 ttccggttgt gtgaaggttt tcatcgcttc ggcaagctgt tcttcattct ctacccgttg
     6841 ataaaggaat ccgcgttctt ccgcccatcc tttggcagat gtcttgtgaa cggctgtaat
     6901 atacttgtgc gatgtacccg acatatccag tccgggtaat gtatggaaaa tctcccctcc
     6961 tccgttattc agcaaaagaa tgcgtagatt gggacggaca ttgatgttcc acaaagcatt
     7021 catatcataa aagaaactaa ggtcacctat aactataaaa tttagtttat ccgaaccggc
     7081 ggcatatccc actgccgtgg acaacgagcc ttcgatgccg cttgtacccc gattacagca
     7141 tacctcaatc gtagaaggaa cctggtataa ctgagcatag cggataacag aactatttgc
     7201 cagatgcaat gcacatgatt ccggcaatgc ttttatcaaa gcaccgatag ccgacatttc
     7261 cgaatatccg aactccggtt cgggaatggt cttgcaataa ttctcccata cacggggata
     7321 ctccggcacg cggtaatcca gccatggagc tattttctcg agaaactcaa acgggtccat
     7381 ttcgatgacg gtagtcagag aaccgtaaag gtcaaccact tctccatcag cagacacatg
     7441 ccaatgttct ttaggcggat gctgccgaag atattttttc aaccgcttgg aaaccacatg
     7501 tccgccataa gtaatcaata actcgggagt catctggccg gttttctctt cgggcatcgc
     7561 ataaagcgcc gcatcaaaat tcttcactgg aataccgggt actgtctgat taccgatatg
     7621 ctcggtcagc cacacgaaat gtttatataa caatttggta tgccgtttct caaacaagta
     7681 aatcaagttc atctgtccga caataatcat ccgcttctga tatctgttca agcgttcgat
     7741 caggtcattg taatcccggt cgtatacatt cagcccctga tagcgcgtaa tgacacgtac
     7801 ttcgggaagc gactccaccg taaactggaa caaaggttcg gatataggaa tattaatatg
     7861 taccggacct tttccatgat ggttggtttc cagcaaggct tcattcacca agcggttaca
     7921 gtaccattca tcctcttctg tctgaatctc cggaaggttt accgacttct tcaccaatgt
     7981 ctgaaaaaca ccgggctgcg gcaatgtctg tcccgccatc tgtccaatcc aggcagcagg
     8041 ccgatcggca gagataacaa ctaaaggtat attctgataa tacgcttctg ccacagcagg
     8101 atgaagattg agcaacgctg taccggaagt acagcaaacg gcagcaggat gcccgccatt
     8161 cagcgcaaga ccaatcgcaa aataaccggc actccgttca tccgtcatag cataacaagt
     8221 aaaacccgga tgagtagaca gcgtatgcac aataggtgca ttacggctac cgggacataa
     8281 cactactttc gtaattccat gcgcctcaag cagcgcgacc aactggagta tatttttctt
     8341 gtccgaatac atattgatag tgattagctt gttagtgatt catcattatt ggagcagaca
     8401 caagaatacg cctcatggtc tgcaatttct tttccgtttc ctgccattca tcattcaact
     8461 ctgaagaggc taacaatccg ccaccggcat acagtgtcaa ttgctcgtct tcaatgtgca
     8521 tgcaacgcag attcacatac aaatctgtgc gtccctccgg atcgagccaa ccgataaaac
     8581 cggaataata cttacgatcg tacccttcat tttccaaaat gaaccggtag gcttcttctt
     8641 taggcagtcc gcacacggca ggagtcggat gcaggacttt cagaaggtct cccagatttt
     8701 tattatcttt caaagagaaa tggaaatcag ttttcagatg tgacaaggca ccggcataag
     8761 ccggataagg tccgctctct gtggagcgaa tgcccagcga aagaagctgc cgacggatat
     8821 aggacgccac ataatcctgc tcctgacggt ttttgtcatc ccatacttgc ggaagtttac
     8881 cattctgcaa aggttgagtt cctgccaggg caactgtgtt ccattcattt ttttcgcccg
     8941 acaatataat ttcgggggta cttcccagcc acacgcccgt ctgaggagta taacacagat
     9001 agatatagga atgaatataa cgttgacaag ctgcacgaaa aacagctgaa ggggaaaact
     9061 ccggattctt tccaatagtg agactacggg aaagcaccag tttatcaaag gtagcatcac
     9121 gcaaggcttc aataaatgta tgaaaacagg tcgcatactt cccagtacaa agggtatgaa
     9181 aagattcctc cggataactt tgcaagtcct gctcttcctc tgccacgatt tccataggca
     9241 acggttgtcc agtcctgtcg gactgtatca acacaatcgg acatgactta tctatacgga
     9301 acggagcaat cacaaatcct ctttgtccat tcagttcttt caaatcgaaa atcaagcgga
     9361 cagctccgac atcttctgtc aacagacgag gatacttctc cccgggaaca cgataaacag
     9421 caaagggctg tttccgctga ataagtgcat caatagttgt caagttactt ttttcgtcaa
     9481 tcatcttttt ttcatcacac tgttgaccac ccgtatagag gacaccagtt tattggttga
     9541 agtaaaaacg tccacattcc atacatggga ggaacgtcct ttgtgtacaa tcgtcgctac
     9601 tgcacgtact gtatcacctt cgtgcgcaga agatatatga tttccgctga cctgcattcc
     9661 taccacaatt tcatccggct gacagagaat catcgagccg agtccggcaa ctgtttctcc
     9721 caatgcaagc gtagctccac cgtgcaaaat accgaacggc tgacgggtac ggtgatctac
     9781 cggcatcgtc gcctctacac ggtcttcgtc ggcatatgta tattggatac ccagattacc
     9841 catcaatgcg tgacgcgcct gtgcattcaa ctggtccaaa ggaatctctg cagcgcgaac
     9901 ttccgctatt atcgcctttt cgacagccag agccactccg tcttcctcat tggaagctgt
     9961 cacataatcc gcacagacct ttaccgaatc ctgcgaatgc cccatcgcca ctcccagtcc
    10021 tgccagctga atcatcgtta catcgcacac accgtctcct atagcgatga cttcttcacg
    10081 cttcacatcc agttcttcca ataaagctcc caatgtgttg gctttatcaa tcgcacacgg
    10141 cactacttcc agaaaataag gttcggaacg gaaaacatcc aaagctccgt tcaaccgtct
    10201 cttccagtgt ccttccagac taaccaacgc ttcctcgtca tcgctgacaa gcatacactt
    10261 acacggagca aagtcaattg ctacagaaaa ttcctcttcc ttgatcactt tcaaattatt
    10321 caagcgagct tcattctgga tatgttcatt ctccggagtg tcagtaatga tcgtatcatc
    10381 atggtaagtg aacagtgcga aattattttt tcttgccttc ttttccagat aaggcaacat
    10441 ttccggatta atcctccgct caaacagtat ttctccgttt tgagcattaa ttatctggca
    10501 accattataa gaaaggatat aacctccata atttccgagt tctagggatt tggctaaagg
    10561 catcagaccg taagtcggtc ggccggatgc caacacgata cgtactccca tctgctgaac
    10621 tttcagcaaa gcagccaatg tacgtttact aatttctttt gcatcattga gaagcgttcc
    10681 gtctacatca agaactaata atttatactt catggacaca cgattttgat ttagattaca
    10741 aaggtaggaa attgagtgaa cgactgaaag cggaaagaga taaaaattac tttaatttca
    10801 ctctttcaga tgcatttcca aataatcacg aaggattcgg gcatgattat aaaccggttc
    10861 tttggatgca taaagcaaag tgatcaccgg atgaggtttg ataagagtca gaaaatcggc
    10921 aacagcttga gaagcttcca gttccttctg atacattacg acaaaatcat tccagtgacc
    10981 cggaatatct tcatgaaacc atctgcgcag tgctgcggaa ggcgttatat cttttgccca
    11041 gtaatcatat ttcaaccatt cttttttgat tccacgtggc cagagtttat ctaccagcac
    11101 ccgatatccg tcggtctctg aaaagtcttc gtacactcgc tttatcctaa cttgcaccat
    11161 ttccgtttat atttagttat cataagaata aaccgataaa acggaaaatt gtttatcgaa
    11221 a
//
