LOCUS       c00004_gnlPro..        12016 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BPMBGEMI_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:49:51
            Original ID  :: gnl|Prokka|BPMBGEMI_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12016
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12016
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2016]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..2016
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..12016
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12016
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..1274
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Gly_radical (E-value: 1.6e-46, bitscore:
                     149.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 2.6e-174, bitscore:
                     572.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TWVTESLGGRLNDGRTKVTKTSFRFLQTLYNLGPSPEPNLTVLWS
                     PELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQSDDYGIACCVSYQEIGKQIQFFGAR
                     CNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTLKFEEVMDNYKKVLTEIARVYNEAM
                     NIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGLSIALDSLSAIKYAKVTARRNDIGL
                     TEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEELKKLPVYKNARPTLSLLTITSNVMY
                     GKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIASLSSVAKLRYRDSQDGISNTFSIVP
                     KSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLNRDMLYDAMEHPENYPQLTIRVSGY
                     AVNFVKLSREHQLEVISRSFHERM"
     CDS             1288..2016
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="Radical_SAM (E-value: 1.2e-28, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(2009..2386)
                     /locus_tag="ctg4_3"
                     /transl_table=11
                     /translation="VDTAHRYRGFSCWGYHYYIRKSGEIEPMRDEDTVGAHARGYNAIS
                     LGVCYEGGLDENGKAADTRTPRQKEALHRLVHELLQRYPEAKVVGHRDLSPDTNYNGIV
                     DPWERIKECPCFEVIGEFSIN"
     CDS             complement(2445..2612)
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(2672..3175)
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             3369..3599
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             3686..5800
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(5870..6175)
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(6156..6329)
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLKTEITPKKEIDKAK
                     ILRKEYYGSKNK"
     CDS             6346..6762
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFYFSPHFQISPPIEADFRKYLLSL
                     MCKRSKESDMDNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(6878..7189)
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MSTKNNMLTDISAELDKEFGAPGTPEREKFDEEAYAFYTGQILLD
                     ARREAKVTQSELAKRINATKSYISRIESGAINPSVGTFYRIINALGLKIEIVKPIMGI"
     CDS             complement(7161..7502)
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MRRKVIAYGQYYKDFLATLTEKEIQKVKYVLSLLGTEDRLPIKFI
                     KVIRDGLYELRISYNGNIYRIFFIFDEGQIVVLFNGFHKKTQKTPSSEIDKALKIKEEY
                     YEYKKQHAD"
     CDS             complement(7595..7849)
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYVSVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGKFE"
     CDS             complement(7867..8001)
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLGLIDQKKELSSN"
     CDS             complement(8119..9477)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 153.4; E-value: 2.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_15"
                     /sec_met_domain="MFS_1 (E-value: 2.7e-47, bitscore: 153.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDPERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     WGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPSNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(9493..10413)
                     /locus_tag="ctg4_16"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKKDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQAPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
ORIGIN
        1 cgacctgggt aaccgaatct ctgggcggac gtctcaacga cggacgtacc aaagtgacaa
       61 agacctcctt ccgtttcctg cagacattgt acaacctcgg cccttcaccg gaaccgaacc
      121 tgaccgtact ctggagcccg gaacttccgg aaggattcaa agaattctgt gcaaaggttt
      181 ctatcgacac ttcttctatc cagtacgaaa atgacgacct gatgcgcgaa gtacgtcagt
      241 ccgacgacta cggaatcgcc tgctgcgtat cataccagga aataggtaag cagattcagt
      301 tcttcggcgc ccgttgcaac ctggccaaag ccctgttgct tgccatcaac ggcggacgtt
      361 gcgagaatac cggtacagtc atggtgaaga acatccccgt gctgaccagc gacacgctga
      421 agttcgaaga agtaatggac aactacaaaa aagtgctgac cgaaatcgcc cgcgtatata
      481 acgaagcgat gaacatcatc cactatatgc acgacaagta ttactacgag aaggcccaga
      541 tggctcttgt agatacgaac ccgcgcataa accttgctta cggtgtagcc ggactttcca
      601 tcgccctcga ttcactgtct gccatcaaat atgcgaaagt aactgcccgc cgcaatgata
      661 tcggtctgac agaaggcttc gacatcgaag gagaattccc ttgcttcggt aacgacaacg
      721 acaaggtaga ccaccttggc gtagacctgg tatacttctt cagcgaagaa ttgaagaaat
      781 tgcctgttta caagaatgcc cgtcctaccc tctccttgct gactatcact tccaatgtga
      841 tgtacggcaa aaagaccggt gctactcccg acggacgtgc caaaggtgtt gccttcgctc
      901 cgggtgccaa cccgatgcac ggacgcgaca agaatggtgc gatcgcttct ctgagctctg
      961 tagcgaaact tcgttaccgt gactcacagg acggtatcag caacaccttc tctatcgttc
     1021 cgaaatcact gggtgctacg gacgaagacc gtatcgagaa cctcgtaacg atgatggacg
     1081 gttacttcac caaaggtgcc caccacctga acgtaaacgt actgaaccgt gatatgctgt
     1141 acgatgccat ggagcatccg gaaaactatc cgcagctgac tatccgcgtt tccggctatg
     1201 ccgtaaactt cgtgaagctg agccgcgaac accaactgga agttatcagc cgtagcttcc
     1261 acgaacgtat gtaatctatt actctatatg atgataaacg tacattcata cgaaagtatg
     1321 ggaacattcg acgggccggg cttacggctc gtcgtttttc ttcaaggatg caacttccgc
     1381 tgcctctatt gcgccaatcc ggatacgata gcaggaaagg gaggcacgcc taccccaccg
     1441 gaagaaatcg tccgcatggc aatgagccag cgccccttct tcgggaaacg aggaggaatc
     1501 actttctccg gaggcgaacc gacgtttcag gcaaaagcac tcgtcccgct ggtccgcgaa
     1561 ctgaaagaaa aaggcatcca tgtctgtctg gacagcaacg gaggactttg gaacgaagac
     1621 gtagaagaat tattcagact gaccgatctt gtgttattgg atataaagga attcaacccc
     1681 aaccgccatc agacgctcac cggaagaagc aacgagcaaa ccatccgcac ggccgcctgg
     1741 ctggaagaac aggagaaacc tttttggcta cgctacgtgc tagtgcccgg atacagcgat
     1801 tttgaagaag acatacgcgc actgggagaa gcactcggaa aatacaagat gatccaacgg
     1861 gtggaaatac taccttacca tacactgggc gtacataagt acgaagcgat gggacaggaa
     1921 tacaagatga aaggggtaaa agaaaatacc cccgaacagc ttgaaaaagc tgcggaggta
     1981 ttcaaagagt atttcactac ggtggtagtt aattaatgga gaattctcca atgacctcaa
     2041 agcaagggca ttctttaatc cgttcccaag gatctacgat cccattatag ttggtgtcgg
     2101 gacttaaatc ccgatgccct actactttag cttccggata acgctgcaac aattcgtgta
     2161 ccaagcgatg tagcgcctcc ttctgacggg gtgtacgcgt atccgcagct tttccattct
     2221 catccagacc gccctcataa catacaccta agctgatcgc attatagcca cgtgcatgag
     2281 ctccgaccgt atcttcatcc cgcatcggct caatctcgcc cgacttgcgt atataataat
     2341 gataccccca gcacgaaaag ccacgataac ggtgagccgt atccacatcc tttgccgtaa
     2401 agtcgcaatc gacacgggtg gcggaacaat ggatcacaat cagactaatc tttctcatgt
     2461 tccttttccc tttccgtcgt tttcactttg cacacctcct tacaggtagt atgatagcgc
     2521 acttctctca ccaccctgtc ccgctttctc tttccgaaga aaggaatcag atacatgatc
     2581 acatctaaaa tccggtttac tatttctttc atcttatcaa aatattaatg gaagttattc
     2641 taattcgtta ttaccttgac ccgtctgcca attataccgt agggtcggga gcctcttcat
     2701 caccggagcc atcaccaccg gaatccggat tcttgtcagg gtcttctccc ccgccatcgc
     2761 ctgcacccgc ctgcgccacc gcacgagtct gcacttgctg ataactcaga atcttcatca
     2821 actccgccag cgtcttaccg gggcggaaaa taagatgcgc ccccttaatc attgaaccgg
     2881 aaaattcctt gaccgatgcc gcaccttcac tgttcagtcc tatctgcaaa ctgcccaaat
     2941 cgcccagtct cgcaattctt cctgccttca acgcacgttt cacttcgtaa agaatacccg
     3001 aaatagccgc acgtacatcc gtttccgtac aagtagaacg actggtgatc gcttcgcaca
     3061 actcttcaaa gtccagctca cccgacgcct gcgcctgtgc ataatacttt gccggttcgc
     3121 tcttttttgc aggattcttg cgcggcacca ctgaataaga tactgtcatt gccataataa
     3181 aataatttta aagtttataa tacataggat gcatcccctt cttgttaaca gcacaaagat
     3241 aaggatagcc ggacaagcca tattccccaa cgaagtttct tgattcccaa cgaataaaaa
     3301 cgaagtcaaa cctttgaata acaaggaatt ttatgtaact ttatagcata aaacaagaag
     3361 aaaacatcat gaattacaaa gaagattctt tccttatccg cacctatacc aaagcggaac
     3421 tggctcacct ttacaatccc catgtctgcc tcaaagttgc tttacaaata cttcgtcgtt
     3481 ggattattta caacctccct ctcctgcacg aactcgaaca ggaaggctac cgcgcacgca
     3541 accgtctcct ttcgccgaaa caagtggcaa ctatcataca ctttttgggc gaaccgtagt
     3601 aacttattgc cattttatac aaagttcctt tacacatttc cgcaaagaag ttcctttgca
     3661 tcgacaaaca ataatcaaaa taaaaatgaa acatttcacc atatttcaag gtttctacta
     3721 cgcaatagca gagatgaccg aagaagaaat agtgtccact atcggcagtt ttacctaccg
     3781 ggaaaaagtc gaagaaatac gccgcatctt tgcagagcaa ggagaaaagg ctgccaatga
     3841 gaagaaaaaa gaattgccgg caatcgcctt ctccgccagc taccgaggaa ggcgtaccaa
     3901 agtgaacctc gtcaaatatc tgggacacat cgtgatagac atcgaccacc tcagcaaaga
     3961 agaattggca cgcatcctcc ctatcatcaa gagatgcgat tacacccgca tcgcctttat
     4021 cagccccaaa gggatgggcg tgaaaatcat agtacgcgca tgccatccgg atgagacatt
     4081 gcccgaaacc cttcaggaaa tagaagactt ccatcatgca gcttacacca gactcgtttc
     4141 tttttacacc gaactctgtc agatagaaat cgacacctcc ggtcaggatg tggcacgcac
     4201 ttgtctgttc tcttacgatc cggagattta tttcaatccg aacgctgacg cttttcttgt
     4261 agatcaacct caggcatcct acaaggtttc aaatcgtaaa aatctctccg gcagtaaaca
     4321 acagactcct ccggacggcc ccccgacgaa tgaagacaca gcgctcaacg cccattccgc
     4381 taacgcttct ctggtgctga ctttaaccta ctatcacaac aagtccgaaa aatacatagc
     4441 gggcaaccgg aacaattatc tgcaccatct ctcatgtacc ttcaatcgct acggcattcc
     4501 gcaggaggaa gcatccgcct ttatcaaaag ccagtttaca gactttccgg cggacgagac
     4561 agcctctttg atcaatagcg cctacgctca taccgacgaa tttaatacct gtaaactgaa
     4621 tggcacgcag aaacgaatat tacggataga gcaatatatc agcgagcact acgaaacacg
     4681 ctacaacgaa gtgctgcata tcatggaata tcgcagaagg catcccgaca ccgagaaacc
     4741 ggagcctttc cgcatcttgg atgagatgat ggaaaacagt atctggatag aaatcaacga
     4801 gctgggatat ccctgcactg tcaaaacaat cgaaaatctg atttactccg atttcagcca
     4861 gtcgtatcat cccattcgcg agtattttga attactgccc gaatgggacg gaaccgacta
     4921 tatccgtatc ctggcggata gtgtccagac gagtcatcag gagttttggg cggaatgcct
     4981 ggaacgttat ctggtggcga tgtgcgcagc ggctactcag gagaatattg tcaatcacac
     5041 ggtacttctg ctatgcagcg agatacagaa cataggaaag actaccttta tcaataatct
     5101 cctgcctccc gaactgcgtg cttatctctc taccggacta atcaattcga acaataaaga
     5161 tgatttagcc aaaataacgc aggctatgct gatcaatctc gacgagtttg aagggatgag
     5221 cggccgggaa ctgaatgcat tcaaagattt ggtaacgcgc aaagtgatca gtttccgtct
     5281 gccttacgca cgccgttcgc aaaacttccc tcatacggcc tcttttgcag gaacctgcaa
     5341 ttatcaggaa gtgcttcacg acacgacagg caaccggcgt ttcctttgtt ttcatcctta
     5401 ttccatccaa tttattacca tcaattatgc gcagctctat gctcagatca aatatctgct
     5461 gaataagccg ggatatcaat actggttcac gcaagcggac aatgaacggc ttgaagagaa
     5521 taacgaggct ttcatctttc attcaccgga agaagaaatg gttcttacgc atatccgcaa
     5581 accagaacgt ttcgagaagg tttattatct gactgtcagt gagattgcgg aactaatacg
     5641 tgagcgtacc ggttatcagt attccatcgg atcaaaaata cagttgggga aggtgatgac
     5701 taagcaccat tttgaatcta aaaaaggaaa taacgggcgc cgatatgccg tatttattat
     5761 agatatcgag caggtaaaat caaacaggct gtatgaatag aagcgggaaa gccttgtgaa
     5821 tatagcaaaa tgcagagtca tcttgacaga tactctgcat ttattgtttt tacaaaatca
     5881 ttgaaaattc gattttacag cctaacgcat tcattatacg atagaaagta gatactttag
     5941 gctctgtctg accactttct actcttgaaa tataagaacg gtcagaaccg atacgccggg
     6001 ctaattcagc ctgagtgatt ttagcctttt ttcttgcgtc ctcgataatc tgtcctgtat
     6061 aaaaggcgta ggccttttct tctgcctctg cacgagaagc tgttccttcc ttaccaaaac
     6121 gctcatctat taatgcactg acattaaaga attcctcatt tgtttttgct tccataatac
     6181 tcctttctta atatctttgc tttatcaatt tctttctttg gtgttatttc ggttttcagc
     6241 acatacaata tcttatcttg ggtgccagca tctaaatttt caaagaattc tttgaagtat
     6301 cctttatatg ctattatttc tcttttcata acgcaaatat aagaaatgtt gttcaactat
     6361 acaacacatt tcctcgtttt atattatttt tcatcatctt cacccccaaa agtgagagga
     6421 gtgagagagg aattgaaact ttttctattt tatttcttta tttctacttt ctatatttct
     6481 ctaaaaaaaa tacgaatgtt agaaatcctc tctcactcct ctcacttttt accttttctt
     6541 tctccaaaaa gacggcggga aatcggaaaa acacaaccgt cttttttcta tttctcaccg
     6601 cattttcaaa tcagcccacc aattgaagca gacttcagga aatatttgtt atctttgatg
     6661 tgcaaaagat caaaagaatc agatatggac aacttgatgc gtaaacttcc tattggaata
     6721 caaacctttg aagatatacg aaggaagaat atcttattgt aaagatcgga atggaattta
     6781 gtgcagaaag ccggaactta aatcgttggt taatcgaagt gataggaaag taaaatatga
     6841 aaaaccgaag gattaagata tccttcggtt ttttcgacta tatacccatg attggtttta
     6901 cgatttcaat cttcaatcct aatgcattaa taattcggta gaatgttcct acacttggat
     6961 ttatagctcc gctttcaata cgtgagatat acgatttagt tgcattgatt ctctttgcta
     7021 attcagactg agttactttt gcttcccgtc gtgcatccaa cagtatttga ccagtataaa
     7081 aagcgtatgc ctcttcatcg aacttttcac gttccggagt cccaggtgct ccgaactcct
     7141 tatcaagttc tgcgctgata tcagtcagca tgttgttttt tgtactcata atattcctcc
     7201 tttattttta atgccttatc tatttctgat gatggggttt tctgtgtttt cttatggaag
     7261 ccattaaata aaacaactat ttgcccttca tcaaaaatga aaaagatacg gtaaatgttt
     7321 ccgttatatg atatacgtag ttcatataga ccatcacgta taacctttat aaatttgata
     7381 ggcaaacggt cttctgttcc aagcaatgaa agcacatatt tcactttttg aatttccttt
     7441 tctgtcagag tggcaagaaa atccttgtaa tattgaccgt atgctattac ttttcttctc
     7501 attgtgcaaa tataataaaa gtttcaatat catacaactt ttaaagtcga atttatactg
     7561 ctaacgggct taaattccct ctcaggtact cattttattc gaatttccct tccgaataat
     7621 ctgaaaactc tccggcacgt tctttcttct catacgagac caacgtttcg atactgagcg
     7681 ctttcccgtt cttagggctt atgacatcta tcacacttga caaggaccgg aacgtctgtt
     7741 cgcaattcgc atctccatta tacgtcaacc tcccccggtc aatggcacct agaataacag
     7801 aaacataccg tttcggatct ccccgatatt cgataacagt gggcgtcatt tgttcttctt
     7861 cccgaatcag ttggacgaca attctttttt ttggtcaatc agccccaaca gttttttact
     7921 atgcacactg atttgtgcat ctacttcacg aagttcattc ttcaatgaac aaaacaattc
     7981 atcactcaat gaattttcca taaaaacgat ttttattaat tataaaaaag ccattccgga
     8041 aagcacagct attgcctgct tcccgaaatg gtgactaata ccttcaaaaa caatgactct
     8101 atttttactt taatgtactc aatttatttc acttcttttc tctcctgcat tccaaaccaa
     8161 caaagcaaac actactgaaa gcaaggctgc accaatccaa aaccaattga tatatgtaaa
     8221 atcgtaaact tctactccat tttgcaccgt cttctgacct tcgatcagaa tgccactcat
     8281 cacatcctgc aaaccggctc ctatataact cgctataccg acaactccca aagcggctcc
     8341 cgaagcattg ctgggagcaa tatcgacagc catcagtcct cctaaaaaac aaatcagcac
     8401 tccaatgccc aaaccgaaga gcaccatcgc caaagcatcc acccaaaaat gtacccccgg
     8461 aaccaataga aacaaacaaa gagcagacac attcattaat ccgaatatca aagccggaac
     8521 attacgactg ccagcaaaaa acttatctga aataatacct gagaaaaccg tacctacaat
     8581 tccgcataca gaactgatag atataataaa actagcatcc aaagtagaat aacctttttg
     8641 cgcttccaga tagaaaacac cccagctatt gactgcataa cggctgatat acataaaagc
     8701 actggataat gcaagaatcc aaatagcagg attcttcaaa actgctttct gagctttatt
     8761 gaattcctcg gtttgcttac cggaaacgga atgagcatct gacgtccccc accgatctag
     8821 caaaaagccc tgactttgag gcgtatcacg cataaaagca agcatcatca gaaaaccaag
     8881 caaaccaatc actcccgcac cgatcatccc ataacgccat cccatccaac tgaccagcaa
     8941 agcgatggat ataaaagtca gagcttcacc caaattgtgg ctggccgacc aaaagccata
     9001 aaaagtacct cgctctttac tactatacca acgagtcagc gacacaactc ctgatgctgc
     9061 ccccatcgac tgaaaccaac cattcaaccc ccaaaggaga acaaaagcaa agaaagaatt
     9121 cgtgaatccc agacataagt tgatcagagc agaacacaat aatccggtag acataaaacg
     9181 ctttacattg ctacggtcag caagaaagcc attggtcagc ttaccgacgg catatacgaa
     9241 aaaaaggcag gaaccgataa tccccagttg ggtttcggta aaaactccgt cttctacaat
     9301 cggtttacgg attacattca tactcaaacg acaaacataa taaatgccat atccggtagt
     9361 ggcagacaga aaggtagccc aacgaatacg cttgaaacgg acagagcgtt ccggatcagt
     9421 ctctcccccg gacaccggag gagagatttt ataaaaatcc aatagtttaa atcccataaa
     9481 gaagtctata ttttaatgat acgcatcttg gccgttttca ctacgcttct tacgcgattg
     9541 caaatattcc agcagatagg cagtacggtc tgtctgaatg atggccgctc cgagtgtatc
     9601 gatcagataa ccatatcctt cgtccggatt ctccaacgat ttatcatcat catgtccgcc
     9661 agccatcgta tcccacaacg tattatacca gattttactt tttcctttca acttcgtttt
     9721 tacttgcttg ggggcctggc aggtatccga tacaaataga agttcaaaag ctacgggatg
     9781 cagctccgtc ataaaatcat ccagttgctt cattgctccc ggcttatcca aatgaatgat
     9841 aggcatataa atgatacggt ccagatattt acctaagtct ttctttacgt ctgccacagg
     9901 cttggaacct ttcatgataa tctgatccac tgttcccgtc ttttcgagga tgggaaaaat
     9961 ctcgtcaaat atcggatatg ctttatccag attgaccatc acacgacctt tggcaaccca
    10021 taaagcctct tccaaagtag gtacacgatg cttggttttg agtgccgctc catttttcag
    10081 atagagtgtc cggatagaat ccaatgtcca ttcggctacc tttccttttc cggtagtcgt
    10141 tcggtccagc gttttgtcat gcatcaggat caattgaccg tctttggttt tctgaacatc
    10201 cagctccact acgtcagctc ccagacgaat ggaactttca atagcggcaa gtgaattttc
    10261 gggtgcgtaa cgccagtctg cccgatgagc tacaaccgtg atttctttat tgtcagggtt
    10321 cgttatcttc gcataaatgg ctttcaccgg ttcgtctgcc gacaggcaga aaggaaatgc
    10381 gaataagatt cctatcatta tatatttctt catatctata tgtactatta tctgtatcct
    10441 ttagacttta aatatttggc agctacttca gcatagtctg tttgcacaat gttgatgcgt
    10501 ttgttaatca ttcccaccaa accggagtag ttttccgaca acatattggt atcattcgct
    10561 ccgacaatgt tggagaaaag aagccagcct ttatctttaa tctcattaac catcgttcca
    10621 cccatagcat ctgacgtaga cagctgcatc atttgtacat tatcagtgta ggatgaggag
    10681 aagtatgtga tgtcatcggt agctttcgcc atcgggtgca acagcaaact actgttggct
    10741 gccttcaaat caaatgcata attgcgattg ttggatacat acagcaaagt ggaaccttcc
    10801 atatccaatt ttttaagcaa tgcgacgatc gtatttaccg caacattctt gttgacaata
    10861 tccagattat aataaacttt tccttttcct ttcttcatcg cttcctccaa agtcgggatt
    10921 cgttcgccag ttatattgcc ggatgcatct ttcagataaa attgttgtaa ttgctgataa
    10981 gtaaagtctc ccaccgcacc gctaccgttt gttgtccggt cgatggtgtt gtcgtgcatc
    11041 aataccaaca caccgtcaga ggtcggccgt gcatccagct cgatcatctc aactcctgct
    11101 ttgaccgagt gttctatcgc aggtaacgag ttttcgggaa tcccctcttt catccctttt
    11161 tgggtatttc cacgatgcgc gcagagccac actttataag aggtgctttc aaacagactc
    11221 tttaaatctg ctttcaaatt ccccgtcaca ggcaactgtc ctccttcttc tccaccggga
    11281 ttctctccat tccctcccga ttgggctccg gagtgacgtc tgtccttccc tttcatcggc
    11341 caggcagagg ttgcggcccc ggtaattccc tcatcttcca aagctaccaa cacgctcttt
    11401 gtagggtcca ccgtattggt gactccgata taaatcgctc catccggtcc gatggtaggc
    11461 gaactccaga ttttaccgat tcccgcttcc caatctcctt ttaaaggaga gtcactttca
    11521 ctaatcaacg cagcaaggtc ttttttcaga atcaattgtt catccgattc ttccggttta
    11581 atgatataat aattgccgga ctgggtgccg aaatgtatgt ttcctgcttg atcaattgcc
    11641 gcacaaccgc ttacatcttc cgcaatgccg taatgccatt ggatagctcc tcccggagac
    11701 aaagagatga ttcctccggt tgcttccccc ggagcacgtt tcactgtaac gataatgctt
    11761 ccgtcgagtc ctatcacaac accgccttga tccagcgtgc cgacattgcc caaaggagta
    11821 cgccacttct ccactccatc acttcctata gcaaatgcgc tacttcccat tcctgcaaac
    11881 gtagctgttc cgtaaatagt accagcctca tctactgccg gagaaccgtt catattttct
    11941 gacggcttat catcgccgga gctaaatacc tgccaagccc acattacatt tccaccggca
    12001 ttcaacgcag aagcag
//
