LOCUS       gnlProkkaAJINIBHF_19   10657 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJINIBHF_19.
ACCESSION   gnlProkkaAJINIBHF_19
VERSION     gnlProkkaAJINIBHF_19
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 07:58:32
            Original ID  :: gnl|Prokka|AJINIBHF_19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10657
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..117
                     /locus_tag="ctg19_1"
                     /transl_table=11
                     /translation="MVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     protocluster    1..10657
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1343:5657]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1344..5657
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10657
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10657
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             132..1280
                     /locus_tag="ctg19_2"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1344..2063
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-16, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2084..3385
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3402..4526
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.8e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4536..5657
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg19_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.2e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4626..5633
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg19_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg19_6_Aminotran_5.1"
                     /locus_tag="ctg19_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5654..5797
                     /locus_tag="ctg19_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6000..7484
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.3e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7438..8697
                     /locus_tag="ctg19_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             8706..9455
                     /locus_tag="ctg19_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             9455..10495
                     /locus_tag="ctg19_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 attgtgcctg gtaaggctaa gaagaaaggg aacatagcta atattttagg ttatgctact
       61 tccttcagtt ctttgggaat gatgattgct tctattgcta atcttataaa gaaataatag
      121 aatttacttt tatgtcagaa caacgacagg ataaaaactt gctctctgaa ccacacaaga
      181 cagaaagtga tgagatagaa attgatttgg tcgatatctt tcgcaagatt attgctattc
      241 gtaaaaaatt atacaaagcc gttggaattg gttttattat tggaataatt gtagcggtaa
      301 gtatccctaa acagtataca gtaaaggtta ccctttctcc tgaaatgggt aatgcgaagg
      361 ggagtaatgg tttagccgga cttgctgcct cgtttttagg agatggggct ctaatagggg
      421 aaagcacaga tgccttgaac gcttctcttt cagcagatat tgtttcttca actccttttt
      481 tattggaact tttagaaatg gaagtctccg tttctaaaaa ggatgataaa atgactttgg
      541 ggtcttatct cgatgaagag tcatctcctt ggtgggatta tcttataggt tttccgggca
      601 tagtaatagg aggagttaaa tcattattcg gagaagatac ggttcctgcc agtggagggc
      661 ggcaaggaac tatcgaattg acgaaagaag taaatgagaa gattaatttt cttaaaaaga
      721 agattagtgc atccattgat aagaaaaccg ccataacgag cattacggtc accttacaaa
      781 atccgcagat cactgcggtt atagcagatt ctgtcgttca taaattacag gaatatatta
      841 ttgggtatcg aacttcaaaa gtaaaagaag actgtgcgta tttggaacgg ttgtttaaag
      901 aacgtcagca ggaatattat gctgctcaaa gaaaatatgc ggattatgta gacgcccatg
      961 ataatgtggt tcttcaaagt gtacgtgctg agcaggagcg tttacagaac gacatgagtt
     1021 tggcttatca gatatatagt caggttgcta atcagttgca ggtatccaga gccaaagtac
     1081 aggaggaaaa gccagtcttt gcagtagttg agcctgccgt tgtacctttg aaaccttcag
     1141 gtatgggact caaaatttat attttattat ttgtgttcct gtccgtatct ggtactctcg
     1201 tgtgggtgtt ttttggcaaa agtctgctgg ctagcttgag aaaagaactg aaaaataagg
     1261 agatagaaca ggataaatga tgctaaaacg tcgtttacaa cattcttaca tcaattaaat
     1321 tcacttacta tattattaaa cgaatgatac gtacagctat gataatggct gcgggcatgg
     1381 gaacccgttt tggccaatat acagaattga tacctaaagg gttcgtcaaa gtgggaggta
     1441 ttccaatgat agttcgttct attgatactt tgttatcatg tggcattgag cgaattgtaa
     1501 tcggtacagg atataaacaa gaagtttatg aagaattgaa gacagactat cctatgcttg
     1561 aaacctgttt tagtcctcgt tatgctgaaa caaatagtat gtatacttta tataatacgc
     1621 gggagattct gggcaatgat gattttttat tgttagagtc agatttgatt tttgagaaac
     1681 aagcaataat gagcttattg gagtgtcctg cggcagatgc aatgctaata gctccagtga
     1741 caaagtttca agatcagtat tatgtggaac atgatgataa ttttcgcctt tcttcatgtt
     1801 ctgtcaataa gaataaacta aacgctaaag gcgaattggt cggcatccat aaactatccg
     1861 gttcctttta caaaataatg tgtgctgatt atgcgagtat tgttgatgaa caacccaatt
     1921 tgggatatga gtatgaatta ctacgaatat cttgttctca atctcctgtt tatgtgcata
     1981 aagtagaagg gctgaaatgg tatgaaatcg atgacatatc agatttggaa tatgcagaga
     2041 aatatattgt tccgtattgt taattaaaat aatatatcaa attatgagta agacagttta
     2101 tattgggatg actgcggata ttatgcatcc aggacttatc cgcattatta atgaggctac
     2161 taaatacggt gatgttataa ttggtcttct tacagataaa gctattgcgg agcataaacg
     2221 ccttccttat ctgacctatg aacaacgaaa agaggtagtt cagaatatta aaggcgtatg
     2281 taaagttgtt cctcaagaag aatggagcta tgttgagaat ctcaaacgca ttaaacctga
     2341 ctatataatt catggtgacg actggaaaac cgggccttta cgtgaagaac gtgtgcgcgt
     2401 atttgaagtg atgaatgaac agggaggaaa ggttatcgaa attccatata ctttgggaat
     2461 taattcatct tctttggata aagatattaa ggctataggt acaacccctg atgtacgttt
     2521 aaaatcactt cgtcgtttga taaatgccaa acccgtagtt cgtattttgg aagctcatga
     2581 tggactatgt ggcttgataa ttgaaaatca ggaaatatta aaaggggata agagggaagt
     2641 atttgacgga atgtggtcta gtagccttac ggattcaacc agtaaaggta aacctgatat
     2701 tgaggcggtt gatttaacta cccgattgca agatttgaat aatattctgg agtgtactac
     2761 taaacctatt atttttgatg gagatacagg tggtaaaatt gaacatttcg tatttacagt
     2821 acgcacttta gaacgtcatg gaatttcagc tataataatt gaagataaag ttggattaaa
     2881 aaagaattca ttgtttggta cagatgttat tcaaactcaa gatacaatcg aaggtttctg
     2941 taataagatc aaagcaggaa aggcatctca gattactgat gattttatga ttatcgctcg
     3001 tattgagagc cttatagcgg gaaagccggt aagtgatgct ttagagagag cttttgcata
     3061 tgtccaagcg ggagcggacg gtattatgat acatagcaaa aataagtcgg gtgaagatat
     3121 aaaagaattt tgtttggcgt ttcgaaaaca gtatgctcat gtacctatcg tggttgtgcc
     3181 tactacatat gatcatattt atgagtctga attgtgtgat tggggtgtga atataattat
     3241 ttatgctaat catatgcttc gtgccgctta tcctgctatg atgaatgtcg caaagataat
     3301 attagagaat gaacgtgctt tagaggtgcg cgaactgtgt atgcccataa aagaaatatt
     3361 ggaactgatt ccaggtacta aataaaaaga ggaatatcat tatgttaagc gtagaaaaag
     3421 tttatgaaac gtttctgagt catgacgttg atttttttac aggagttcca gactcattac
     3481 taaaaaatat ttgtgcctat atcacagacc atacttcacg tgagaaacat atcatagctg
     3541 ctaatgaagg tgcggctgta ggaattgctt caggttatta tatggcatca ggtaaggttc
     3601 ctgtggttta tatgcaaaat tccggcttgg gtaatactgt taatcctctg ctgtctcttg
     3661 cagatgaaca agtatacagt tttccaatgc ttttgatgat tggctggcgt ggtgaaccgg
     3721 gaacaaaaga tgaacctcag cataaaaaac agggtgaggt aactttagat ttgttgaaag
     3781 caatgcggat tccttatata attcttgatt caaatgagaa tgatgcattt attcagctcc
     3841 atgatatcat acaatcagca aaaactaaga atattcctca tgcaataatt attcggaaag
     3901 atgtttttgg caaatataaa cttcaaaaag agttcggatg taattatcct ttatctcgtg
     3961 aggatgcttt gcaaatagtt gtggattatc tgcctgaaaa ttcagtggtc gtttctacta
     4021 ctggcaagct ttctcgtgag ttatttgaat atcgagaaat gaaagagcaa ggtcatgaac
     4081 atgattttct cacggtaggc tctatgggac atagttcatc aatctctttg ggtattgcta
     4141 tagcaaagca agatagacct gtttattgct tggatggtga tggagcattt attatgcatt
     4201 taggggcaat tagtaacatt ggcgatttat ctcctaaaaa ctattatcat attttgttta
     4261 acaatggtgc tcacgagtct gtaggaggac agcctacttt aggatttagt ttagatattc
     4321 cggctattgt ccgggggagc ggatataagc atacttatac tgtttgtaca aaagttgaaa
     4381 ttgaagaagc aatgaagcag cttccaaagt tatgtggtcc tgttttgttg gaaataaagg
     4441 ttaaaataga ttctcgggag aatttgggac gtcccacgac tactcctata gagaataagg
     4501 agcattttat ggatttttta aaataaatat attcgatgaa aatagaaaga aaaatattat
     4561 taaatcctgg gcctgccact actactgaca gtgtaaaaat ggcacaagtt gttccggata
     4621 tttgtcctcg cgagaaagaa ttcgcaggta tgatgaaaca acttcgggac gatttggtca
     4681 gagttgctca tgggaatttg gaaaaacata ccgctgtatt attttgtggc tcaggaacca
     4741 tcaatattga tatatgtcta aattctcttc ttcctgaaga caaaagggtg cttatagtga
     4801 ataatggggc atatagtacc cgtgctgtag aagtgtgtca atattatggt ttgcctcata
     4861 ttaatttgga attttccgtt tacgaacgtc ctgatttatc ggtggtggaa aatgtgttgc
     4921 aagaaaatcc tgatatagct atggtttata ctactcatca cgagacgggt acaggaattc
     4981 tgaaccctat tcgcgagatg ggcgctatag ctcataaata tcaggctaaa tttgtcgtcg
     5041 atactacttc ttctttgggc atgattcctt ttgatataga gaaagataat gtggattttt
     5101 gtatggcatc tgctcaaaaa ggacttcaag cgatgacagg tctttctttt attataggca
     5161 atgaggaaca gattaagttt tcaaaaaaat atcccaagcg ttcttactat tgtaatcttt
     5221 atttgcagta tgagaatttt gagagaacag gtgaaatgca ttttactcca ccggtacaaa
     5281 ctatttacgc cactcgtcag gcattaaatg aatattttga agtgggtgaa gaagctaagt
     5341 ttgcccgtca caaaagagtt tttgaggcta ttcattcagg tataaatgaa attggtctta
     5401 aaagtgtaat aaagcgtgaa tggcagtcag gactggttgt ctcagttcaa tacccagaag
     5461 atcccaactg ggattttgag aaaatacatg attattgtta tgagcgtgga tttacgattt
     5521 atccaggtaa gatatcaact gaggatactt ttagaatctg tgctttagga gagatagaag
     5581 tagatgatat tgagaacttc tttaaagtac taaaagctgc attaaatcat tataacgtca
     5641 cattaccgat gtcatgattg cagaaatatt attgaagatt cgtcattttt atttttccct
     5701 tcgtggtata cacttccatc cggaaagtgt tatttctgga gtgcctattc gtagctttcg
     5761 cttagtaggc aaatatggca atattaattt gaggtgatgc attaggagtt ctttattctt
     5821 ataaaaaggc atcggtagtt ataggagata atgtttgtgt agggtaattt gcttttagtg
     5881 ggagagacca tattagaatt gcggtaaggg gcgaagaaga taataaccaa ttagtgagaa
     5941 tattggaaaa atataattga tatcggtaaa tgtagttgtt tttatactgt atttaagtaa
     6001 tggaaaatct aaagcagaaa actgtatcag gaataatgtg gagcgctata gaacgtttct
     6061 ctttacaagg agtacagttt ataattcaaa taatattagc tcgtttgtta ctaccatcgg
     6121 attatggtat gatcgggatg ttagctattt ttcttcaagt cgctcaagta tttatagata
     6181 gcggttttac aaatgcttta atccagaaaa aagatagaac tgaagaggat tttgccactg
     6241 tcttttattt taatattctt gtcgcagtat tattctatgg tatattgttt ttttcggctt
     6301 ctttgattgc agacttttat aatatgccga ctttagttct tgtaattcgt tttatagcat
     6361 tgtcgttgat aataaatgct ttatcggcta ttcacagaac gaaattaatt atttctgtaa
     6421 actttaaaac tcaatctaaa atttcattag gtgcagcttt tatatcaggc gtgattggaa
     6481 tatggatggc ttatgtcggt tgcggggttt gggctttagt ttggcaaact ctcttaaata
     6541 gtataatttt gacaattttg ttttactgtt tagttcattg gaaaccttta catactttct
     6601 ccaaaagttc ttttgaaaga ttattcaatt tcggatctaa attattgatc tcaagtctta
     6661 tcaatacagt atatcgtaat ctgtatacca ttgtaatagg aaaaaagttt tctgttgtag
     6721 agcttggtta ctatacaaga gcagaacaat ttgctatttt tccttccaat aatttaaatg
     6781 ctttagtttc tagagtagcg tatcctattt taagttccat tcaagatgat gataaatgtt
     6841 taacaaacgc atatcgaaat tatatcagat tatcctcata tataattttt cctttaatgg
     6901 taggtttact tgttttggct aatcctatta ttagtctatt gttaacagat aaatggtctg
     6961 gggttgttat tcttttacag atattatgtt tggattggat gtttgatcat ttgagccaaa
     7021 ttaatttgaa tttattatgg gttaaaggaa gatctgatct gtcgttacgt cttgaaataa
     7081 taaaaaagac gattgctata ttcattcttt ttgtgtcaat tccatttggg cttgaggtga
     7141 tgtgttgggg tagagttatt tactctctga tagcgacata tttgaataca tattatacta
     7201 attctcttat tgatttgacc ttaaagttgc aagttaaaga tgtatttcca agtttaatac
     7261 tctctttcat aatggggggg atcgttttta tatgtatttc tttctttgaa actgatatag
     7321 taaaaattgt gattggatgt attactggga tgtccttcta tattttactt tcttttcttt
     7381 ttaagctaga ttcttttttt tgtattttaa cattgatcat taaaactaaa aacatagatg
     7441 aaaatattaa aaaagatttt tcaagtaata gtaaagataa ttaaccattg tgtgccagtt
     7501 gatagtagat cattgtattt tattcctcat cctaattgta gaacagataa atatgatatt
     7561 ataaattatt cgtcagataa tgttctcgtt ctgttaaatt atttgctaaa aaaagatagt
     7621 gctgaatatt ataaaatata tgttgaaatt tatgattctt ctcgtatttc agaatatcaa
     7681 gaatatattt atggcataaa tcctaatatt aggtgtactt ttttatgtgc atgtgttgga
     7741 cgttttttct ttaataaagt atcttttaag gatatgttgt atgccttttt ttgtttttgt
     7801 agagcaagta aatgttttac agctactttt tattatgatt tttcatttaa aaaacgctct
     7861 caacagatta tttgtttggg gtattatact ccattcaaag atgattatca tatgggagat
     7921 cattcttatg ataaatttcg taatacaaca tgtaactcat ttgattactc tattgctact
     7981 tcttgtttaa gtgctagaat aatttcaata gattgtggaa tctcatatga taaattcaaa
     8041 gtcttaggat ttcccagaaa tgatttgttg atatcgaaaa ataattgcaa tgttattaaa
     8101 agagaaattt cgaaatttgc gggatatgat gtaactaaat atatagttta tactccaact
     8161 tttcgtgatt atgagactgt tactgaaggt aatttgcgtt caatactcgg atatgttgat
     8221 tgtgatttgt tgaagttatc gaaaatacta ttgaagttta atgcggcttt aattcttaaa
     8281 ttacatcctt tgcagaataa aacagtctta aaaaaagatt tacccaaagg tatacttgtt
     8341 tttgaacaaa catataaata tggattgtat gatcttttgt cattttcaga tggaatgatt
     8401 actgattata cttctaccta ttttgatttt ttattggtaa ataagccagt catatttaat
     8461 ttctacgata ttgaagaata tcgtagagta agaggtttct catttgagcc aatagaattt
     8521 ttttgtgcag gtgatattgt ttacaattat aatgaattga tagatgctgt gatgggactt
     8581 ctggctggga aagatattca tgctgaacat cgacgtcata tttctttatt gatgaatcaa
     8641 tttcaagatg ataattcaac aaagagaata tgtgacatat ttttaaatga aatataataa
     8701 ataaaatgaa ttatgcattt gtggtgcagg cacgtttagg ttctacacgt ttgcctggaa
     8761 aaatattgaa acctttctat ggtaatcaat cgattcttga cttaatggtt cataagcttt
     8821 ctgctatatc gaatattcca gtaattattg ctacaacaaa ttctgttatc aatgaaccta
     8881 ttgaaaagaa ggcacttgca ttaggggtaa agtgcttcag aggtgaggag aatgatgttt
     8941 taaaacgatt cattgatgtt gctgaatatt ttgatataca gggtatattc cgaatatgtt
     9001 ctgataatcc atttttagat gtacatgcgg caaggcaatt ggtcgaaata gcaatgaaat
     9061 cttgtaacga ttatataagt tttgatattg atggtactcc atcaattaaa actcatttcg
     9121 gtttttgggg agaatttgta acgcttgatg cgctgaagcg agttatagga tttactgatg
     9181 atttattgta tcgtgaacat gttactaatt atatatatag tcatcctgaa ctttttaata
     9241 ttcaatggat ttcaggatct ccagtcgtgt caaaacatca taatattcga ctcacgattg
     9301 atacgttaga agatttttct gtagcacaga gaatatatag ggatttacaa gaaaaaagag
     9361 tggaaatatc gatagaagtg attgtagact atgttcgaag acatgcagaa tacattcaac
     9421 tgatgaaaca acaaataaaa aaaaattcta aataatgaag aatacttata ttattggtga
     9481 aatagggcag aatcataatg gttctgttga cttggctaag ttgattattg aattaatctc
     9541 acgacctgta catgaggatg tttttggtat ggatttcatg ccaatgaatg ctgttaaaat
     9601 gactaaaaga gatttatcag aagaattggc tgtttctcaa atgaatcaaa tatatgacaa
     9661 tcctaattct tttgggcgta cttatggtga acatcgtgct tttcttgagc ttgatgatca
     9721 agcgcatttt gagatttata aatatgctaa gtcattagga ttagatttta tcgagacgtt
     9781 atgtgccaaa ggatgtctgt ctttgcttaa actgttcaca ccggataggc taaaagttgc
     9841 tagtcgtgat ttgactaact taccattgct tgaagcatta gcagaaactc atattcctat
     9901 tatattatcg acaggaatgg ctggtcaaag agaacttgac aatgcattag atgtgataac
     9961 gagatatcat agtaatatag ctattctaca ttgtgtatct cagtatccaa ctcatccaaa
    10021 taatttgaat ctacgtacaa taacatattt gaagaagcat tacaataagt ttgagatagg
    10081 tttttctgat catacaatag gtatttctgc tgctacagct gctgtagcga tgggagcgga
    10141 aattatagaa aagcatgtaa caattgatcg gcatatgaaa ggaacagacc agcttggctc
    10201 tttaggtcca gatggggtta atcgtatgat tcgagatatt cgcatagcag agtgttggct
    10261 tggtactgaa gatctttata tagaaaaagg ggtggagaag tctaagataa aacttgaacg
    10321 ttctattgcc actcgaaaat atattccagc aggtagtatt attcaagagt cggacattca
    10381 tttactgagt cctggtgatg gttataaatg gatagataaa aaaaatgtaa ttggtcattt
    10441 tgctaaacaa gatatatcag cgaatgaaat aatatatcct gattttattg aatagatata
    10501 ttcctactgc aacttgtatt acggtataga gtactgcctg ctataagcta agtagtgatt
    10561 aataaataag ggtaaaatac taaaaaaatg aaagagataa agcttatact tacagatatt
    10621 gatggcgttt ggactgatgg cggaatgttt tatgatc
//
